Search of human proteins with 45505151

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
         (499 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]              1023   0.0  
gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]               844   0.0  
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]              577   e-165
gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]              575   e-164
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]              575   e-164
gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]               538   e-153
gi|93004092 nuclear factor I/B [Homo sapiens]                         502   e-142
gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact...   460   e-129
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             65   1e-10
gi|116284392 mucin 2 precursor [Homo sapiens]                          51   3e-06
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                50   6e-06
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                50   6e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          48   2e-05
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          48   2e-05
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          48   2e-05
gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]      47   4e-05
gi|239747686 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]      47   4e-05
gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain contai...    47   4e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   5e-05
gi|222418647 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|222418649 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|222418645 mucin 7, secreted precursor [Homo sapiens]                44   3e-04
gi|163965366 nascent polypeptide-associated complex alpha subuni...    44   3e-04
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  44   4e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   44   4e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   44   4e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   44   4e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    44   4e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    43   6e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    43   6e-04

>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
          Length = 499

 Score = 1023 bits (2644), Expect = 0.0
 Identities = 499/499 (100%), Positives = 499/499 (100%)

Query: 1   MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK 60
           MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK
Sbjct: 1   MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK 60

Query: 61  QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR 120
           QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR
Sbjct: 61  QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR 120

Query: 121 LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDA 180
           LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDA
Sbjct: 121 LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDA 180

Query: 181 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSL 240
           EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSL
Sbjct: 181 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSL 240

Query: 241 GELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSS 300
           GELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSS
Sbjct: 241 GELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSS 300

Query: 301 SRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHP 360
           SRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHP
Sbjct: 301 SRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHP 360

Query: 361 SSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420
           SSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ
Sbjct: 361 SSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420

Query: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480
           LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV
Sbjct: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480

Query: 481 GLGPRDPAGIYQAQSWYLG 499
           GLGPRDPAGIYQAQSWYLG
Sbjct: 481 GLGPRDPAGIYQAQSWYLG 499


>gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
          Length = 428

 Score =  844 bits (2180), Expect = 0.0
 Identities = 413/413 (100%), Positives = 413/413 (100%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ
Sbjct: 11  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 70

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 71  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 130

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE
Sbjct: 131 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 190

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG
Sbjct: 191 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 250

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 301
           ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS
Sbjct: 251 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 310

Query: 302 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS 361
           RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS
Sbjct: 311 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS 370

Query: 362 SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 414
           SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP
Sbjct: 371 SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 423


>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
          Length = 501

 Score =  577 bits (1488), Expect = e-165
 Identities = 325/519 (62%), Positives = 379/519 (73%), Gaps = 38/519 (7%)

Query: 1   MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVK 60
           MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVK
Sbjct: 1   MDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVK 60

Query: 61  QKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWR 120
           QKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWR
Sbjct: 61  QKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWR 120

Query: 121 LDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDA 180
           LDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+
Sbjct: 121 LDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADS 180

Query: 181 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSL 240
            QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL
Sbjct: 181 SQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSL 238

Query: 241 GELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSS 296
            +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S
Sbjct: 239 SDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGS 295

Query: 297 PTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIA 355
            + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G  
Sbjct: 296 GSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPR 350

Query: 356 RSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 414
            SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G 
Sbjct: 351 ASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQ 405

Query: 415 L-----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPT 463
           +     NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPT
Sbjct: 406 VGFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPT 463

Query: 464 SPSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499
           SP+YS P TSPANR FV +GPRDP+ +    Q QSWYLG
Sbjct: 464 SPTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 501


>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
          Length = 554

 Score =  575 bits (1483), Expect = e-164
 Identities = 324/518 (62%), Positives = 378/518 (72%), Gaps = 38/518 (7%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 55  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 114

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 115 KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 174

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 175 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 234

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 235 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 292

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 293 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 349

Query: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 350 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 404

Query: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G +
Sbjct: 405 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 459

Query: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464
                NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPTS
Sbjct: 460 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 517

Query: 465 PSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499
           P+YS P TSPANR FV +GPRDP+ +    Q QSWYLG
Sbjct: 518 PTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 554


>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
          Length = 509

 Score =  575 bits (1483), Expect = e-164
 Identities = 324/518 (62%), Positives = 378/518 (72%), Gaps = 38/518 (7%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 10  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 70  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 190 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 248 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 304

Query: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 305 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 359

Query: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G +
Sbjct: 360 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 414

Query: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464
                NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPTS
Sbjct: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 472

Query: 465 PSYSPPDTSPANRSFVGLGPRDPAGI---YQAQSWYLG 499
           P+YS P TSPANR FV +GPRDP+ +    Q QSWYLG
Sbjct: 473 PTYSTPSTSPANR-FVSVGPRDPSFVNIPQQTQSWYLG 509


>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
          Length = 498

 Score =  538 bits (1385), Expect = e-153
 Identities = 306/500 (61%), Positives = 357/500 (71%), Gaps = 44/500 (8%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 10  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 69

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 70  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 129

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 130 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 189

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 190 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 247

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 297
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 248 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 304

Query: 298 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 356
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 305 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 359

Query: 357 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G +
Sbjct: 360 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 414

Query: 416 -----NGSGQLKMPSHCLSAQMLAPPPPGLPRLALP-----PATKPATTS-EGGATSPTS 464
                NGS Q K+ +  L   ML PPPP  P +A P     P TKP TTS EGGA SPTS
Sbjct: 415 GFLNPNGSSQGKVHNPFLPTPMLPPPPP--PPMARPVPLPVPDTKPPTTSTEGGAASPTS 472

Query: 465 P----------SYSPPDTSP 474
           P          S+ PPD  P
Sbjct: 473 PILVPGIKVAASHHPPDRPP 492


>gi|93004092 nuclear factor I/B [Homo sapiens]
          Length = 420

 Score =  502 bits (1293), Expect = e-142
 Identities = 268/414 (64%), Positives = 316/414 (76%), Gaps = 16/414 (3%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELL EKPE+KQ
Sbjct: 11  DEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLSEKPEIKQ 70

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIR E REDFVL++TGKK P CVLSNPDQKGK+RRIDCLRQADKVWRL
Sbjct: 71  KWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDCLRQADKVWRL 130

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERL+K+  C +P LCVQPHHI V+VKELDL+LAY+V+E+D+ 
Sbjct: 131 DLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFLAYYVQEQDSG 190

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QSGSP     +D   + P  L     ++SFV SGVF+V+EL++VSRTP+  GTG NF +G
Sbjct: 191 QSGSP---SHNDPAKNPPGYL-----EDSFVKSGVFNVSELVRVSRTPITQGTGVNFPIG 242

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 301
           E+     Y    +   L+R+L S  S  SKR K+ S++E+++ SP GD+Y SPSSP + S
Sbjct: 243 EIPSQPYYHDMNSGVNLQRSLSSPPS--SKRPKTISIDENMEPSPTGDFYPSPSSPAAGS 300

Query: 302 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQD-SPRLSSFTQHHRPVI--AVHSGIA-RS 357
           R W E  +  +SSP    + +K  F+S SPQD SPRLS+F QHH P I    HS I+ R+
Sbjct: 301 RTWHE-RDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRT 359

Query: 358 PHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQ 411
           P P S L FPT +ILP   S+YF H  IRYPPHLNPQD LK+ V  + DP+S Q
Sbjct: 360 PPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVP-SYDPSSPQ 412


>gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor)
           [Homo sapiens]
          Length = 441

 Score =  460 bits (1184), Expect = e-129
 Identities = 261/441 (59%), Positives = 305/441 (69%), Gaps = 26/441 (5%)

Query: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61
           DEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPE+KQ
Sbjct: 10  DEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEIKQ 69

Query: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121
           KWASRLLAKLRKDIRPE REDFVL+ITGKK P CVLSNPDQKGK+RRIDCLRQADKVWRL
Sbjct: 70  KWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQADKVWRL 129

Query: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181
           DLVMVILFKGIPLESTDGERL K+ QC +P LCVQPHHIGV +KELDLYLAYFV   ++ 
Sbjct: 130 DLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYFVHTPESG 189

Query: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241
           QS S          D KP+      FQ+ FVTSGV++VTEL++VS+TPV T +GPNFSL 
Sbjct: 190 QSDSSNQ---QGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATASGPNFSLA 246

Query: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS---GSMEEDVDTSPGGDYYTSPSSPT 298
           +L+    Y++N  + G R      S+S +KR KS     ME  VD         SP++ +
Sbjct: 247 DLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTGRSPAAGS 306

Query: 299 SSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIA-VHSGIARS 357
           S S  W  D++ G +S  K  ++D     S S   SPR+ +FT H  PV+A V  G  R+
Sbjct: 307 SQSSGWPNDVDAGPASLKKSGKLDFCSALS-SQGSSPRM-AFTHHPLPVLAGVRPGSPRA 364

Query: 358 PHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNG 417
              +SALHFP+TSI+ Q +S YF H  IRY  H + QD LK+ V   C   S Q      
Sbjct: 365 --TASALHFPSTSII-QQSSPYFTHPTIRYHHH-HGQDSLKEFVQFVCSDGSGQ-----A 415

Query: 418 SGQLKMPSHCLSAQMLAPPPP 438
           +GQ         +Q  APP P
Sbjct: 416 TGQ--------HSQRQAPPLP 428


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 61/207 (29%), Positives = 82/207 (39%), Gaps = 6/207 (2%)

Query: 285  SPGGDYYTSPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQH 343
            SPGG    SPS SPTS S + T       S     T    SP +      SP  S  +  
Sbjct: 1604 SPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1663

Query: 344  HRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYP--PHLNPQDPLKDLV 401
            + P    +S  + S  P+S  + PT+     T+ +Y P +    P  P  +P  P     
Sbjct: 1664 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1723

Query: 402  SLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGL-PRLALPPATKPATTSEGGAT 460
            S +  P S    P + S     P++  ++    P  P   P       T P  T      
Sbjct: 1724 SPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNY 1783

Query: 461  SPTSPSYSP--PDTSPANRSFVGLGPR 485
            SPTSPSYSP  P  SP + S+    PR
Sbjct: 1784 SPTSPSYSPTSPSYSPTSPSYSPSSPR 1810



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 64/239 (26%), Positives = 93/239 (38%), Gaps = 9/239 (3%)

Query: 252  NPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPS-SPTSSSRNWTEDMEG 310
            +P S     T PS S +    + S +      TSP     TSPS SPTS S + T     
Sbjct: 1616 SPTSPSYSPTSPSYSPTSP--NYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYS 1672

Query: 311  GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 370
              S     T    SP +      SP  S  +  + P    +S  + S  P+S  + PT+ 
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1732

Query: 371  ILPQTASTYFPHTAIRYP--PHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCL 428
                T+ +Y P +    P  P+  P  P     S +  P S    P + +     PS+  
Sbjct: 1733 SYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSP 1792

Query: 429  SAQMLAPPPPGL-PRLALPPATKPATTSEGGATSPTSPSYSP--PDTSPANRSFVGLGP 484
            ++   +P  P   P         P  T    + SP+SPSYSP  P  +P + S+    P
Sbjct: 1793 TSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSP 1851



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 69/270 (25%), Positives = 106/270 (39%), Gaps = 20/270 (7%)

Query: 213  TSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKR 272
            TS  +S T       +P  + T P++S        +   +P S     T PS S +    
Sbjct: 1695 TSPSYSPTSPSYSPTSPSYSPTSPSYS------PTSPSYSPTSPSYSPTSPSYSPTSP-- 1746

Query: 273  HKSGSMEEDVDTSPGGDYYTSPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSP 331
            + S +      TSP     TSPS SPTS +   T       S     T    SP +    
Sbjct: 1747 NYSPTSPNYTPTSPSYSP-TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYS 1805

Query: 332  QDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRY---P 388
              SPR +  +  + P    +S  + S  P+S  + PT+     ++  Y P T+ +Y    
Sbjct: 1806 PSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTP-TSPKYSPTS 1864

Query: 389  PHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGL----PRLA 444
            P  +P  P     S    P + +  P + +     P +  ++   +P  P      P+ +
Sbjct: 1865 PKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYS 1924

Query: 445  LPPATKPATTSEGGATSPTSPSYSPPDTSP 474
                T   T+ +G   SPTSP YSP  TSP
Sbjct: 1925 PTSPTYSPTSPKGSTYSPTSPGYSP--TSP 1952



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 69/272 (25%), Positives = 101/272 (37%), Gaps = 32/272 (11%)

Query: 213  TSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKR 272
            TS  +S T       +P  + T PN+S             P S     T PS S +    
Sbjct: 1723 TSPSYSPTSPSYSPTSPSYSPTSPNYS-------------PTSPNYTPTSPSYSPTSPSY 1769

Query: 273  HKSGSMEEDVDTSPGGDYYTSPS-SPTSSSRNWTEDMEGGIS---SPVKKTEMDKSPFNS 328
              S +      TSP     TSPS SPTS S + T       S   +P   T    SP  S
Sbjct: 1770 --SPTSPNYTPTSPNYSP-TSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYS 1826

Query: 329  PSPQD----SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTA 384
            PS       SP+ +  +  + P    ++  +    P+S  + PT+     T+ TY P T 
Sbjct: 1827 PSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTT- 1885

Query: 385  IRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLA 444
                P  +P  P     S    P S +  P + +     P +  ++   +P  P   + +
Sbjct: 1886 ----PKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSP---KGS 1938

Query: 445  LPPATKPATTSEGGATSPTSPSYSPPDTSPAN 476
                T P  +      S TSP+ SP D+   N
Sbjct: 1939 TYSPTSPGYSPTSPTYSLTSPAISPDDSDEEN 1970



 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 43/158 (27%), Positives = 61/158 (38%), Gaps = 3/158 (1%)

Query: 330  SPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPP 389
            SP  +   S F+  + P  +   G   SP PSS         +  + S   P    R P 
Sbjct: 1547 SPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPG 1606

Query: 390  HLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGL-PRLALPPA 448
               PQ P     S +  P S    P + +     PS+  ++   +P  P   P       
Sbjct: 1607 GYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666

Query: 449  TKPATTSEGGATSPTSPSYSP--PDTSPANRSFVGLGP 484
            T P+ +    + SPTSPSYSP  P  SP + S+    P
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1704



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 42/163 (25%), Positives = 58/163 (35%), Gaps = 31/163 (19%)

Query: 327  NSPSPQD--SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTA 384
            ++PSP    SP ++ + Q   P        A SP   S +        P  AS      A
Sbjct: 1505 SAPSPMGGISPAMTPWNQGATPAYG-----AWSPSVGSGMTPGAAGFSPSAASD-----A 1554

Query: 385  IRYPPHLNPQDPLKDLVSLACDPASQQPG-PLNGSGQLKMPSHCLSAQMLAPPPPGLPRL 443
              + P  +P          A  P    PG P   S  +  P   +S       P      
Sbjct: 1555 SGFSPGYSP----------AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSP------ 1598

Query: 444  ALPPATKPATTSEGGATSPTSPSYSP--PDTSPANRSFVGLGP 484
            A  P +    T +  + SPTSPSYSP  P  SP + ++    P
Sbjct: 1599 AYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSP 1641



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 27/60 (45%), Positives = 28/60 (46%), Gaps = 14/60 (23%)

Query: 436  PPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPAGIYQAQS 495
            P PG P    P  + P   S GGA SP   SYSP  TSPA        PR P G Y  QS
Sbjct: 1567 PTPGSP--GSPGPSSPYIPSPGGAMSP---SYSP--TSPAYE------PRSPGG-YTPQS 1612


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 54/229 (23%), Positives = 81/229 (35%), Gaps = 14/229 (6%)

Query: 252  NPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
            +P +T      P+T+ S      +        + P     T P + T S    T      
Sbjct: 1423 SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTT 1482

Query: 312  ISSPVKKTEMDKSPFNSPSPQDS----PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFP 367
              SP   T     P  +PSP  +    P  S+ T       +  +    +P P++    P
Sbjct: 1483 TPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP 1542

Query: 368  TTS-ILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSH 426
            TT+ I P T++T  P T    PP      P     +    P +  P P   +     P+ 
Sbjct: 1543 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP--TTTPSPPTTTTPSPPTITTTTPPPT- 1599

Query: 427  CLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
                    P PP       PP T P+  +    T PTS +  PP T+P+
Sbjct: 1600 ------TTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 52/203 (25%), Positives = 70/203 (34%), Gaps = 18/203 (8%)

Query: 284  TSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQH 343
            T+P     T+PS PT ++   T        SP   T     P  +PSP   P  +  T  
Sbjct: 1576 TTPSPPTTTTPSPPTITT---TTPPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPITPP 1629

Query: 344  HRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPH--TAIRYPPHLNPQDPLKDLV 401
                    +     P  ++    PTT+  P T +T  P   T    PP   P  P+    
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689

Query: 402  SLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPP-----PGLPRLALPPATK-----P 451
            S      +        S  +   +   S    +PPP     P       PP T      P
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP 1749

Query: 452  ATTSEGGATSPTSPSYSPPDTSP 474
             TTS    T+P  PS +PP  SP
Sbjct: 1750 TTTSSPLTTTPLPPSITPPTFSP 1772



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 44/185 (23%), Positives = 66/185 (35%), Gaps = 19/185 (10%)

Query: 292  TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVH 351
            T+PS PT++             SP   +     P  +PSP   P  ++ T       +  
Sbjct: 1397 TTPSPPTTTP------------SPPPTSTTTLPPTTTPSP---PTTTTTTPPPTTTPSPP 1441

Query: 352  SGIARSPHPSSALHFP-TTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQ 410
                 +P P++    P +T+  P   +T  P T    PP   P  P     +    P + 
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPT---TTTTTPPPTT 1498

Query: 411  QPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPP 470
             P P   +      S         P PP       PP T P+  +    T PTS +  PP
Sbjct: 1499 TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1558

Query: 471  DTSPA 475
             T+P+
Sbjct: 1559 TTTPS 1563



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 56/248 (22%), Positives = 86/248 (34%), Gaps = 25/248 (10%)

Query: 253  PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 312
            PAST    TLP T++       + +       SP     T+P +P +S+           
Sbjct: 1511 PAST---TTLPPTTTPSPPTTTTTTPPPTTTPSPPT---TTPITPPTSTTTLPPTTT--- 1561

Query: 313  SSPVKKTEMDKSPFNSPSPQDS-----PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFP 367
             SP   T     P  +PSP  +     P +++ T       +  +    +P P++    P
Sbjct: 1562 PSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621

Query: 368  TTS-ILPQTASTYFPHTAIRYPPHLN---------PQDPLKDLVSLACDPASQQPGPLNG 417
            TT+ I P T++T  P T    PP            P  P     S      +  P     
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTP 1681

Query: 418  SGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDT-SPAN 476
            S  +       +  M  P P   P   +   T P++T+       T  + SP  T SP  
Sbjct: 1682 SSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPT 1741

Query: 477  RSFVGLGP 484
             +   L P
Sbjct: 1742 TTMTTLPP 1749



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 15/121 (12%)

Query: 357  SPHPSSALHFP-TTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPL 415
            SP P+S    P TT+  P T +T  P      PP   P  P+    +    P +  P P 
Sbjct: 1407 SPPPTSTTTLPPTTTPSPPTTTTTTP------PPTTTPSPPI---TTTTTPPPTTTPSPP 1457

Query: 416  NGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
              +     P+   S     P PP        P+    TT+    T+  SP  + P T PA
Sbjct: 1458 ISTTTTPPPTTTPSPPTTTPSPP-----TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 476  N 476
            +
Sbjct: 1513 S 1513



 Score = 33.5 bits (75), Expect = 0.46
 Identities = 68/307 (22%), Positives = 103/307 (33%), Gaps = 29/307 (9%)

Query: 188  TGMGSDQEDSKPITLDTT----DFQESFVTSGVFSVTELIQVSRTPVVTGTG-PNFSLGE 242
            T  G+    + PIT  TT           T     +T    V+ TP  TGT  P  +   
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041

Query: 243  LQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSR 302
                +     P  T    T P T+++      + +  +   T+P     T   +PT +  
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101

Query: 303  NWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPV-----------IAVH 351
                      ++ V  T    +P  + +P  +P  ++ T    P            I   
Sbjct: 4102 QTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4158

Query: 352  SGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRY--PPHLNPQDPLKDLVSLACDPAS 409
            + +  +P P+      TT I   T  T  P        PP      P+ +L +    P S
Sbjct: 4159 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPES 4218

Query: 410  QQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPA---TKPATTSEGGATS-PTSP 465
              P     +      S  L    L+  PP +   +  P    T P TTS G   S P S 
Sbjct: 4219 STPQTSRSTSSPLTESTTL----LSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPST 4274

Query: 466  SYSPPDT 472
            + SPP T
Sbjct: 4275 TTSPPGT 4281



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 66/294 (22%), Positives = 102/294 (34%), Gaps = 24/294 (8%)

Query: 188  TGMGSDQEDSKPITLDTT----DFQESFVTSGVFSVTELIQVSRTPVVTGTG-PNFSLGE 242
            T  G+    + PIT  TT           T     +T    V+ TP  TGT  P  +   
Sbjct: 4028 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4087

Query: 243  LQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSR 302
                +     P  T    T P T+++      + +  +   T+P     T   +PT +  
Sbjct: 4088 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4147

Query: 303  NWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSP--HP 360
                      ++ V  T    +P  + +P  +P  ++ T    P     +G    P  H 
Sbjct: 4148 QTPTTTPITTTTTVTPTP---TPTGTQTPTTTPITTTTTVTPTPT---PTGTQTGPPTHT 4201

Query: 361  SSA-LHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSG 419
            S+A +   TTS  P  +ST  P T+      L     L   +  A +  S  P     + 
Sbjct: 4202 STAPIAELTTSNPPPESST--PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAP 4259

Query: 420  QLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTS 473
                  H LS      PPP       PP T    T+ G +++PT  +     TS
Sbjct: 4260 TTTSGGHTLS------PPPSTT--TSPPGTPTRGTTTGSSSAPTPSTVQTTTTS 4305


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 20/176 (11%)

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
           + + + +++   SP N+ +P+ S       +  +P  A            S L       
Sbjct: 360 VQANLDQSQRGSSPQNTTTPKPS------VEGQQPAAAAACEPVDHAQSESILKVSQPRA 413

Query: 372 LPQTASTYFPHT-------AIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMP 424
           L Q AST  P         +   PP   P  PL  + + A  P +  P PL G G +  P
Sbjct: 414 LEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKAL-PTAPPPPPLPGLGAMAPP 472

Query: 425 SHCL------SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSP 474
           +  L      S + L PPPP LP L  PP   P     G    P  P   P   SP
Sbjct: 473 APPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 20/176 (11%)

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
           + + + +++   SP N+ +P+ S       +  +P  A            S L       
Sbjct: 360 VQANLDQSQRGSSPQNTTTPKPS------VEGQQPAAAAACEPVDHAQSESILKVSQPRA 413

Query: 372 LPQTASTYFPHT-------AIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMP 424
           L Q AST  P         +   PP   P  PL  + + A  P +  P PL G G +  P
Sbjct: 414 LEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKAL-PTAPPPPPLPGLGAMAPP 472

Query: 425 SHCL------SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSP 474
           +  L      S + L PPPP LP L  PP   P     G    P  P   P   SP
Sbjct: 473 APPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLPGMGWGPPPPPPPLLPCTCSP 528


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 72/269 (26%), Positives = 103/269 (38%), Gaps = 66/269 (24%)

Query: 267 SSGSKRHKSGSMEEDVDTSPGGDYYTS----PSSPTS----SSRNWTEDMEGGISSPVKK 318
           S+  +R K  S  E+ D +      T     P+SP+     SS + + + EG  SS  K 
Sbjct: 92  SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEG--SSDPKD 149

Query: 319 TEMDK--------SPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPH--PSSALHFPT 368
            + D         SP ++ S  DS       Q   P +   +G+  +P   P      PT
Sbjct: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 209

Query: 369 -------TSILPQTASTY-------------FPHTAIRY--------------PPHLNPQ 394
                  T++ PQ + T               PHT I+               PPH +P 
Sbjct: 210 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 269

Query: 395 DPLKDLVSLACDPA--SQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPA 452
            PL+ L   A  P+  S    PL+G G    P    +  +L  P P  P   LPP     
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQP-FGLPP----- 322

Query: 453 TTSEGGATSPTSPSYSPPDTS---PANRS 478
             S+G A   TSP+ + P TS   PA++S
Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQLPASQS 351



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 29/146 (19%)

Query: 358 PHPSSALHFPTTSILPQTASTYFPHT-AIRYPPHLNPQDP------------LKDLVSLA 404
           P P + L  P     P T     P   A ++PPHL+   P            LK L SL+
Sbjct: 363 PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 422

Query: 405 CD-PASQQPGPLNGSGQLK-------MPSHCLSAQMLAPPPP-----GLPRLALPPATKP 451
              P S  P PL    Q +        P     +Q L PPP      GL ++A  P    
Sbjct: 423 THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 482

Query: 452 ATTSEGG---ATSPTSPSYSPPDTSP 474
                GG    T PT PS S P   P
Sbjct: 483 HPFVPGGPPPITPPTCPSTSTPPAGP 508



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 35/156 (22%), Positives = 53/156 (33%), Gaps = 30/156 (19%)

Query: 313 SSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSIL 372
           SSP +   + +S    P P   P         +P  A H  +   P P +    P+TS  
Sbjct: 445 SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 504

Query: 373 PQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQM 432
           P       P T+ + P                C  A+   G + G     +P+  +  + 
Sbjct: 505 PAG-----PGTSAQPP----------------CSGAAASGGSIAGGSSCPLPTVQIKEEA 543

Query: 433 L-------APPPPGLPRLALPPATKPATTSEGGATS 461
           L       +PPPP  PR   P  T   T S    ++
Sbjct: 544 LDDAEEPESPPPP--PRSPSPEPTVVDTPSHASQSA 577


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 72/269 (26%), Positives = 103/269 (38%), Gaps = 66/269 (24%)

Query: 267 SSGSKRHKSGSMEEDVDTSPGGDYYTS----PSSPTS----SSRNWTEDMEGGISSPVKK 318
           S+  +R K  S  E+ D +      T     P+SP+     SS + + + EG  SS  K 
Sbjct: 646 SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEG--SSDPKD 703

Query: 319 TEMDK--------SPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPH--PSSALHFPT 368
            + D         SP ++ S  DS       Q   P +   +G+  +P   P      PT
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 763

Query: 369 -------TSILPQTASTY-------------FPHTAIRY--------------PPHLNPQ 394
                  T++ PQ + T               PHT I+               PPH +P 
Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823

Query: 395 DPLKDLVSLACDPA--SQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPA 452
            PL+ L   A  P+  S    PL+G G    P    +  +L  P P  P   LPP     
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQP-FGLPP----- 876

Query: 453 TTSEGGATSPTSPSYSPPDTS---PANRS 478
             S+G A   TSP+ + P TS   PA++S
Sbjct: 877 QASQGQAPLGTSPAAAYPHTSLQLPASQS 905



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 29/146 (19%)

Query: 358  PHPSSALHFPTTSILPQTASTYFPHT-AIRYPPHLNPQDP------------LKDLVSLA 404
            P P + L  P     P T     P   A ++PPHL+   P            LK L SL+
Sbjct: 917  PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 405  CD-PASQQPGPLNGSGQLK-------MPSHCLSAQMLAPPPP-----GLPRLALPPATKP 451
               P S  P PL    Q +        P     +Q L PPP      GL ++A  P    
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 452  ATTSEGG---ATSPTSPSYSPPDTSP 474
                 GG    T PT PS S P   P
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 35/156 (22%), Positives = 53/156 (33%), Gaps = 30/156 (19%)

Query: 313  SSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSIL 372
            SSP +   + +S    P P   P         +P  A H  +   P P +    P+TS  
Sbjct: 999  SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 373  PQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQM 432
            P       P T+ + P                C  A+   G + G     +P+  +  + 
Sbjct: 1059 PAG-----PGTSAQPP----------------CSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 433  L-------APPPPGLPRLALPPATKPATTSEGGATS 461
            L       +PPPP  PR   P  T   T S    ++
Sbjct: 1098 LDDAEEPESPPPP--PRSPSPEPTVVDTPSHASQSA 1131


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 72/269 (26%), Positives = 103/269 (38%), Gaps = 66/269 (24%)

Query: 267 SSGSKRHKSGSMEEDVDTSPGGDYYTS----PSSPTS----SSRNWTEDMEGGISSPVKK 318
           S+  +R K  S  E+ D +      T     P+SP+     SS + + + EG  SS  K 
Sbjct: 646 SNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEG--SSDPKD 703

Query: 319 TEMDK--------SPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPH--PSSALHFPT 368
            + D         SP ++ S  DS       Q   P +   +G+  +P   P      PT
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPT 763

Query: 369 -------TSILPQTASTY-------------FPHTAIRY--------------PPHLNPQ 394
                  T++ PQ + T               PHT I+               PPH +P 
Sbjct: 764 PGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPH 823

Query: 395 DPLKDLVSLACDPA--SQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPA 452
            PL+ L   A  P+  S    PL+G G    P    +  +L  P P  P   LPP     
Sbjct: 824 PPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQP-FGLPP----- 876

Query: 453 TTSEGGATSPTSPSYSPPDTS---PANRS 478
             S+G A   TSP+ + P TS   PA++S
Sbjct: 877 QASQGQAPLGTSPAAAYPHTSLQLPASQS 905



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 44/146 (30%), Positives = 53/146 (36%), Gaps = 29/146 (19%)

Query: 358  PHPSSALHFPTTSILPQTASTYFPHT-AIRYPPHLNPQDP------------LKDLVSLA 404
            P P + L  P     P T     P   A ++PPHL+   P            LK L SL+
Sbjct: 917  PLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLS 976

Query: 405  CD-PASQQPGPLNGSGQLK-------MPSHCLSAQMLAPPPP-----GLPRLALPPATKP 451
               P S  P PL    Q +        P     +Q L PPP      GL ++A  P    
Sbjct: 977  THHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQ 1036

Query: 452  ATTSEGG---ATSPTSPSYSPPDTSP 474
                 GG    T PT PS S P   P
Sbjct: 1037 HPFVPGGPPPITPPTCPSTSTPPAGP 1062



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 35/156 (22%), Positives = 53/156 (33%), Gaps = 30/156 (19%)

Query: 313  SSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSIL 372
            SSP +   + +S    P P   P         +P  A H  +   P P +    P+TS  
Sbjct: 999  SSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 373  PQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQM 432
            P       P T+ + P                C  A+   G + G     +P+  +  + 
Sbjct: 1059 PAG-----PGTSAQPP----------------CSGAAASGGSIAGGSSCPLPTVQIKEEA 1097

Query: 433  L-------APPPPGLPRLALPPATKPATTSEGGATS 461
            L       +PPPP  PR   P  T   T S    ++
Sbjct: 1098 LDDAEEPESPPPP--PRSPSPEPTVVDTPSHASQSA 1131


>gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
          Length = 875

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 41/260 (15%)

Query: 233 GTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDT----SPGG 288
           G G   SL    G L   + P+      T P+  ++GS    +  +          +PG 
Sbjct: 40  GGGTASSLSVRPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVASSASAVTTKAPGI 99

Query: 289 DYYTSPSSPTSSSRNWTEDMEGGISSPVKKT---EMDKSPFN----SPSPQDSPRLSSFT 341
               S S   ++S  W +       +P+ ++   + D+ P      S +P   P +++  
Sbjct: 100 SKGDSQSQGLATSIRWGQ-------TPINQSTPWDTDEPPSKQMRESDNPGTGPWVTTVA 152

Query: 342 QHHRPVIAVHS-GIARSPHPSSALHF--PTTSILPQTASTYFPHTAIRYPPHLNPQDPLK 398
             ++P +  HS G+A+ P  S A++   P   + P       P   +    +  PQ P +
Sbjct: 153 AGNQPTLIAHSYGVAQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLMPGHYSLPQPPSQ 212

Query: 399 DLVSLACDP------ASQQP---GPLNGSGQLKMPSHC------LSAQMLAPPPPGLPRL 443
            L S+  +       AS QP     L G GQ+  P         ++  +L PPPP  P  
Sbjct: 213 PLSSVVVNMPAQALYASPQPLAVSTLPGVGQVARPGPTAVGNGHMAGPLLPPPPPAQPSA 272

Query: 444 ALP---PATK--PATTSEGG 458
            LP   PAT   P T S  G
Sbjct: 273 TLPSGAPATNGPPTTDSAHG 292


>gi|239747686 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
          Length = 702

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 41/260 (15%)

Query: 233 GTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDT----SPGG 288
           G G   SL    G L   + P+      T P+  ++GS    +  +          +PG 
Sbjct: 40  GGGTASSLSVRPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVASSASAVTTKAPGI 99

Query: 289 DYYTSPSSPTSSSRNWTEDMEGGISSPVKKT---EMDKSPFN----SPSPQDSPRLSSFT 341
               S S   ++S  W +       +P+ ++   + D+ P      S +P   P +++  
Sbjct: 100 SKGDSQSQGLATSIRWGQ-------TPINQSTPWDTDEPPSKQMRESDNPGTGPWVTTVA 152

Query: 342 QHHRPVIAVHS-GIARSPHPSSALHF--PTTSILPQTASTYFPHTAIRYPPHLNPQDPLK 398
             ++P +  HS G+A+ P  S A++   P   + P       P   +    +  PQ P +
Sbjct: 153 AGNQPTLIAHSYGVAQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLMPGHYSLPQPPSQ 212

Query: 399 DLVSLACDP------ASQQP---GPLNGSGQLKMPSHC------LSAQMLAPPPPGLPRL 443
            L S+  +       AS QP     L G GQ+  P         ++  +L PPPP  P  
Sbjct: 213 PLSSVVVNMPAQALYASPQPLAVSTLPGVGQVARPGPTAVGNGHMAGPLLPPPPPAQPSA 272

Query: 444 ALP---PATK--PATTSEGG 458
            LP   PAT   P T S  G
Sbjct: 273 TLPSGAPATNGPPTTDSAHG 292


>gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain
           containing 9 [Homo sapiens]
          Length = 875

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 63/260 (24%), Positives = 101/260 (38%), Gaps = 41/260 (15%)

Query: 233 GTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDT----SPGG 288
           G G   SL    G L   + P+      T P+  ++GS    +  +          +PG 
Sbjct: 40  GGGTASSLSVRPGLLPLPVVPSRLPTPATAPAPCTTGSSEAITSLVASSASAVTTKAPGI 99

Query: 289 DYYTSPSSPTSSSRNWTEDMEGGISSPVKKT---EMDKSPFN----SPSPQDSPRLSSFT 341
               S S   ++S  W +       +P+ ++   + D+ P      S +P   P +++  
Sbjct: 100 SKGDSQSQGLATSIRWGQ-------TPINQSTPWDTDEPPSKQMRESDNPGTGPWVTTVA 152

Query: 342 QHHRPVIAVHS-GIARSPHPSSALHF--PTTSILPQTASTYFPHTAIRYPPHLNPQDPLK 398
             ++P +  HS G+A+ P  S A++   P   + P       P   +    +  PQ P +
Sbjct: 153 AGNQPTLIAHSYGVAQPPTFSPAVNVQAPVIGVTPSLPPHVGPQLPLMPGHYSLPQPPSQ 212

Query: 399 DLVSLACDP------ASQQP---GPLNGSGQLKMPSHC------LSAQMLAPPPPGLPRL 443
            L S+  +       AS QP     L G GQ+  P         ++  +L PPPP  P  
Sbjct: 213 PLSSVVVNMPAQALYASPQPLAVSTLPGVGQVARPGPTAVGNGHMAGPLLPPPPPAQPSA 272

Query: 444 ALP---PATK--PATTSEGG 458
            LP   PAT   P T S  G
Sbjct: 273 TLPSGAPATNGPPTTDSAHG 292


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 57/191 (29%), Positives = 79/191 (41%), Gaps = 22/191 (11%)

Query: 292 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVH 351
           TSPS P S+  + +  ++  +S P            S SP  SP  S  T H  P+ A+ 
Sbjct: 442 TSPSRPASTPPD-SPPLQAPLSLPASPPLQ-----TSLSPAVSPLSSPLTIH--PLQALS 493

Query: 352 SGIARSPH-PSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQ 410
           S  + SP  P S+L  P      +T S+  P  +++ PP      PL++L SLA  P   
Sbjct: 494 SLASHSPQAPLSSLIMPPL----ETQSSLAP-PSLQTPPASLTTPPLENLPSLAPPPLQT 548

Query: 411 QPGPLNGSGQLKMPSHCLSAQMLAPP------PPGLPR-LALPPATKPATTSEGGATSPT 463
              PL  +  L+ P       + APP      PP  P  +A PP   P   +        
Sbjct: 549 ASAPLT-TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607

Query: 464 SPSYSPPDTSP 474
           SP  SP  T P
Sbjct: 608 SPPLSPLATPP 618



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 56/213 (26%), Positives = 76/213 (35%), Gaps = 60/213 (28%)

Query: 293 SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHS 352
           SP +P SS      + +  ++ P  +T         P+   +P L +      P +   S
Sbjct: 499 SPQAPLSSLIMPPLETQSSLAPPSLQTP--------PASLTTPPLENLPSLAPPPLQTAS 550

Query: 353 GIARSPH----------PSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVS 402
               +PH          P  A   P T+  P+T S+      I  PP   PQ P      
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS------IATPP---PQAP------ 595

Query: 403 LACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSP 462
               PA   P PL G     +PS  LS  +  PPP   P LALPP   P +       SP
Sbjct: 596 ----PALASP-PLQG-----LPSPPLSP-LATPPPQAPPXLALPPLQAPPSPPASPPLSP 644

Query: 463 -TSPS---------------YSPPDTSPANRSF 479
             +PS               +SPP + P    F
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 54/177 (30%), Positives = 69/177 (38%), Gaps = 25/177 (14%)

Query: 324 SPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHT 383
           SP  +P PQ  P L++      P + V      SP P S    P   + P  A+   P  
Sbjct: 717 SPSATPPPQAPPPLAA------PPLQVPPSPPASP-PMSPSATPPPRVPPLLAAP--PLQ 767

Query: 384 AIRYPPHLNPQDPL-----KDLVSLACDPASQQPGP-LNGSGQLKM-PSHCLSAQMLAPP 436
               PP   P  PL     +   +LA  P    P P  +  GQ    PS  L    LA P
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 437 PPGLPR-LALP----PATKPATTSEGGATSPTSPSYSPPDTSPAN-RSFVGLGPRDP 487
           PP  P  LA P    P + PA+ +      P +P    PDTS +  R  + L P  P
Sbjct: 828 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG---PDTSVSGPRLTLALAPGPP 881



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 50/180 (27%), Positives = 61/180 (33%), Gaps = 29/180 (16%)

Query: 329 PSPQDSPRLSSF---TQHHRPVIAVHSGIAR-SPHPSSALHFP-----TTSILPQ-TAST 378
           PSP  SP LS     +      +AVH   A  SP PS  +  P     +  + P  T  +
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693

Query: 379 YFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQM---LAP 435
             P +    P  + P  P    +S +  P  Q P PL        PS   S  M     P
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 436 PPPGLPRLALPP----------------ATKPATTSEGGATSPTSPSYSPPDTSPANRSF 479
           PP   P LA PP                A  P       AT P     SPP + P    F
Sbjct: 754 PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 813



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 64/269 (23%), Positives = 88/269 (32%), Gaps = 51/269 (18%)

Query: 257 GLRRTLPSTSS---SGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG-- 311
           GL R  PS      +   R    S  E   T P       PS+     R  +  +     
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247

Query: 312 -ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAV---HSGIARSPHPSSALHFP 367
            +SSP +     +    +P+    P+         P +      +  A  P  SS L  P
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307

Query: 368 TTSIL-------PQTASTYFPHTAIRYPP-----HLNPQDP-----LKDLVSLACDPASQ 410
           + S         P  A+T  P T    PP      L P  P     L+ L S    P SQ
Sbjct: 308 SPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 367

Query: 411 QPGPLNGSGQLKMPS----------HCLSAQMLAPPPPGLPRLALPPATK------PATT 454
            P  +        PS          H L++  L  PP  L   +L   T        AT 
Sbjct: 368 APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATH 427

Query: 455 S---------EGGATSPTSPSYSPPDTSP 474
           S         +   TSP+ P+ +PPD+ P
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPP 456



 Score = 35.8 bits (81), Expect = 0.093
 Identities = 55/228 (24%), Positives = 79/228 (34%), Gaps = 40/228 (17%)

Query: 255 STGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISS 314
           + G    LP  + S   R  +    + V  S   ++ T+  SP +  R       GG+  
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSV--SSASEHSTTEPSPAARRR---PSAGGGLQR 236

Query: 315 PVKK------TEMDKSPFNSPSPQDSPRLSSFTQHHRP--VIAVHSGIARSPHPSSALHF 366
           P  +      T +     + PS + +PR  +     +P  + A+       P   +A   
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296

Query: 367 PTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSH 426
              S  P    +     A   PP  N   PL         PA+  P P      L  P  
Sbjct: 297 GPLSSSPLATPSPSGTKARPVPPPDNAATPL---------PATLPPSP-----PLATPLP 342

Query: 427 CLSAQMLAPP----PPGLPRLALPPATKPATTSEGGATSPTSPSYSPP 470
                 LAPP    PP L  L  PPAT P   S+   +  T P  +PP
Sbjct: 343 ------LAPPSPSAPPSLQTLPSPPATPP---SQAPPSMTTPPMQAPP 381



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 45/178 (25%), Positives = 60/178 (33%), Gaps = 32/178 (17%)

Query: 313 SSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSS-ALHFPTTSI 371
           S+P+    ++  P  +P P  +P     T    P     S IA  P  +  AL  P    
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTT----PPPETPSSIATPPPQAPPALASPPLQG 605

Query: 372 LPQTASTYFPHTAIRYPPHLN-------PQDPLKDLVSLACDPASQQPGPLNGSGQLKMP 424
           LP    +       + PP L        P  P    +S    P+ Q P  L         
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL--------A 657

Query: 425 SHCLSAQMLAPP---------PPGLPRL---ALPPATKPATTSEGGATSPTSPSYSPP 470
            H L A    PP         PP  P +   A PP+  P + +      P SP  SPP
Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715


>gi|222418647 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 56/254 (22%), Positives = 94/254 (37%), Gaps = 37/254 (14%)

Query: 222 LIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEED 281
           L+  ++ P VT    +  +  L        N  +   R  + ++SS  +    +    +D
Sbjct: 105 LVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQD 164

Query: 282 VDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFT 341
              +P     T+P+ P+SS+   T       ++P   +   ++P +S +P ++       
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPET------TAAPPTPSATTQAPPSSSAPPET------- 211

Query: 342 QHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFP-HTAIRYPPHLNPQDPLKDL 400
                  A  +  A +P P S+   P T+  P T S   P   +   PP      P    
Sbjct: 212 -----TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSA 266

Query: 401 VSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGAT 460
            +L  DP+S    P                   APP P     A P +  P  T+    T
Sbjct: 267 TTL--DPSSASAPP---------------ETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 461 SP-TSPSYSPPDTS 473
           +P +SP+   PDTS
Sbjct: 310 TPNSSPTTLAPDTS 323



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/166 (25%), Positives = 62/166 (37%), Gaps = 20/166 (12%)

Query: 324 SPFNSPSPQDS----PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTY 379
           +P NSP+PQD+    P  S+ T       A     A  P PS+    P +S  P   +T 
Sbjct: 155 APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTA 213

Query: 380 FPHTAIRYPPHLNPQDPLK----DLVSLACDPASQQPGPLNGSGQLKMPS-------HCL 428
            P T    PP   P  P      +  +    P++  P PL+ S   +  +         L
Sbjct: 214 APPT----PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTL 269

Query: 429 SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSP 474
                + PP        P AT PA  S       T+   + P++SP
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSP 315



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/172 (22%), Positives = 61/172 (35%), Gaps = 25/172 (14%)

Query: 329 PSPQDSPRLSSFTQHHR----------PVIAVHSGIARSPHPSSALHF---PTTSILPQT 375
           PSP + P+  +  Q  +          P +   + I     PS++      P  + LPQ 
Sbjct: 76  PSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQN 135

Query: 376 ASTYFPHTAIRYPPHLNPQDPL-----KDLVSLACDPASQQPGPLNGSG--QLKMPSHCL 428
           A+T      +     +    P+     +D  +    P++  P P + S   +        
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTP 195

Query: 429 SAQMLAPPPPGLPRLAL-----PPATKPATTSEGGATSPTSPSYSPPDTSPA 475
           SA   APP    P         PPAT PA  S       T+   +P  T+PA
Sbjct: 196 SATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPA 247


>gi|222418649 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 56/254 (22%), Positives = 94/254 (37%), Gaps = 37/254 (14%)

Query: 222 LIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEED 281
           L+  ++ P VT    +  +  L        N  +   R  + ++SS  +    +    +D
Sbjct: 105 LVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQD 164

Query: 282 VDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFT 341
              +P     T+P+ P+SS+   T       ++P   +   ++P +S +P ++       
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPET------TAAPPTPSATTQAPPSSSAPPET------- 211

Query: 342 QHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFP-HTAIRYPPHLNPQDPLKDL 400
                  A  +  A +P P S+   P T+  P T S   P   +   PP      P    
Sbjct: 212 -----TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSA 266

Query: 401 VSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGAT 460
            +L  DP+S    P                   APP P     A P +  P  T+    T
Sbjct: 267 TTL--DPSSASAPP---------------ETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 461 SP-TSPSYSPPDTS 473
           +P +SP+   PDTS
Sbjct: 310 TPNSSPTTLAPDTS 323



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/166 (25%), Positives = 62/166 (37%), Gaps = 20/166 (12%)

Query: 324 SPFNSPSPQDS----PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTY 379
           +P NSP+PQD+    P  S+ T       A     A  P PS+    P +S  P   +T 
Sbjct: 155 APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTA 213

Query: 380 FPHTAIRYPPHLNPQDPLK----DLVSLACDPASQQPGPLNGSGQLKMPS-------HCL 428
            P T    PP   P  P      +  +    P++  P PL+ S   +  +         L
Sbjct: 214 APPT----PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTL 269

Query: 429 SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSP 474
                + PP        P AT PA  S       T+   + P++SP
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSP 315



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/172 (22%), Positives = 61/172 (35%), Gaps = 25/172 (14%)

Query: 329 PSPQDSPRLSSFTQHHR----------PVIAVHSGIARSPHPSSALHF---PTTSILPQT 375
           PSP + P+  +  Q  +          P +   + I     PS++      P  + LPQ 
Sbjct: 76  PSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQN 135

Query: 376 ASTYFPHTAIRYPPHLNPQDPL-----KDLVSLACDPASQQPGPLNGSG--QLKMPSHCL 428
           A+T      +     +    P+     +D  +    P++  P P + S   +        
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTP 195

Query: 429 SAQMLAPPPPGLPRLAL-----PPATKPATTSEGGATSPTSPSYSPPDTSPA 475
           SA   APP    P         PPAT PA  S       T+   +P  T+PA
Sbjct: 196 SATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPA 247


>gi|222418645 mucin 7, secreted precursor [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 56/254 (22%), Positives = 94/254 (37%), Gaps = 37/254 (14%)

Query: 222 LIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEED 281
           L+  ++ P VT    +  +  L        N  +   R  + ++SS  +    +    +D
Sbjct: 105 LVATTQIPSVTFPSASTKITTLPNVTFLPQNATTISSRENVNTSSSVATLAPVNSPAPQD 164

Query: 282 VDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFT 341
              +P     T+P+ P+SS+   T       ++P   +   ++P +S +P ++       
Sbjct: 165 TTAAPPTPSATTPAPPSSSAPPET------TAAPPTPSATTQAPPSSSAPPET------- 211

Query: 342 QHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFP-HTAIRYPPHLNPQDPLKDL 400
                  A  +  A +P P S+   P T+  P T S   P   +   PP      P    
Sbjct: 212 -----TAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSA 266

Query: 401 VSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGAT 460
            +L  DP+S    P                   APP P     A P +  P  T+    T
Sbjct: 267 TTL--DPSSASAPP---------------ETTAAPPTPSATTPAPPSSPAPQETTAAPIT 309

Query: 461 SP-TSPSYSPPDTS 473
           +P +SP+   PDTS
Sbjct: 310 TPNSSPTTLAPDTS 323



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/166 (25%), Positives = 62/166 (37%), Gaps = 20/166 (12%)

Query: 324 SPFNSPSPQDS----PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTY 379
           +P NSP+PQD+    P  S+ T       A     A  P PS+    P +S  P   +T 
Sbjct: 155 APVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTPSATTQAPPSSSAPPE-TTA 213

Query: 380 FPHTAIRYPPHLNPQDPLK----DLVSLACDPASQQPGPLNGSGQLKMPS-------HCL 428
            P T    PP   P  P      +  +    P++  P PL+ S   +  +         L
Sbjct: 214 APPT----PPATTPAPPSSSAPPETTAAPPTPSATTPAPLSSSAPPETTAVPPTPSATTL 269

Query: 429 SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSP 474
                + PP        P AT PA  S       T+   + P++SP
Sbjct: 270 DPSSASAPPETTAAPPTPSATTPAPPSSPAPQETTAAPITTPNSSP 315



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/172 (22%), Positives = 61/172 (35%), Gaps = 25/172 (14%)

Query: 329 PSPQDSPRLSSFTQHHR----------PVIAVHSGIARSPHPSSALHF---PTTSILPQT 375
           PSP + P+  +  Q  +          P +   + I     PS++      P  + LPQ 
Sbjct: 76  PSPNNPPKFPNPHQPPKHPDKNSSVVNPTLVATTQIPSVTFPSASTKITTLPNVTFLPQN 135

Query: 376 ASTYFPHTAIRYPPHLNPQDPL-----KDLVSLACDPASQQPGPLNGSG--QLKMPSHCL 428
           A+T      +     +    P+     +D  +    P++  P P + S   +        
Sbjct: 136 ATTISSRENVNTSSSVATLAPVNSPAPQDTTAAPPTPSATTPAPPSSSAPPETTAAPPTP 195

Query: 429 SAQMLAPPPPGLPRLAL-----PPATKPATTSEGGATSPTSPSYSPPDTSPA 475
           SA   APP    P         PPAT PA  S       T+   +P  T+PA
Sbjct: 196 SATTQAPPSSSAPPETTAAPPTPPATTPAPPSSSAPPETTAAPPTPSATTPA 247


>gi|163965366 nascent polypeptide-associated complex alpha subunit
           isoform a [Homo sapiens]
          Length = 2078

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 66/254 (25%), Positives = 88/254 (34%), Gaps = 39/254 (15%)

Query: 251 LNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSS---PTSSSRNWTED 307
           L P ++  +      S + +     G++    D+        SP +   PT       + 
Sbjct: 760 LAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDT 819

Query: 308 MEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFP 367
             G +SSPV   E    P NS S Q S + S  T H             SP P S    P
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGS-KDSPATTH-------------SPTPPSPKGAP 865

Query: 368 TTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHC 427
           T S     A T      +  PP   P   + +L      PA+  P     +  L M S  
Sbjct: 866 TPS-----AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAP---KQAPALSMTSSS 917

Query: 428 LSAQMLAPPPPGLPR------LALPPATKPATTSEGGAT-----SPTSPSYSPPDT--SP 474
                  P P G+P          PPA  P +   G AT     +PT P+ +PP     P
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 475 ANRSFVGLGPRDPA 488
           A  S  G  P  PA
Sbjct: 978 ATPSPKG-APTPPA 990



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 50/189 (26%), Positives = 66/189 (34%), Gaps = 34/189 (17%)

Query: 287  GGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 346
            GG    SP    +         +GG ++P  K          PSP+ SP  + F     P
Sbjct: 975  GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPF-----P 1029

Query: 347  VIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACD 406
              A     A  P P  +   P  + LP+ A T     A    P   P  P   L      
Sbjct: 1030 KGASTPPAATPPSPKGS---PAATPLPKGAPT--TPAATLPSPKGGPATP--SLKGAPTP 1082

Query: 407  PASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGAT-----S 461
            PA+  P P  G                 P P G P   +PPA  P +   G AT     +
Sbjct: 1083 PAATPPSPKGGPA--------------TPSPKGAP---MPPAATPPSPKGGLATPPHKGA 1125

Query: 462  PTSPSYSPP 470
            PT+P+ +PP
Sbjct: 1126 PTTPAATPP 1134



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 57/215 (26%), Positives = 79/215 (36%), Gaps = 45/215 (20%)

Query: 285  SPGGDYYTSP--SSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQ 342
            SP G   T P   +PT  +      ++GG+++P  K   + +    PSP+  P  S    
Sbjct: 1250 SPKGGPATPPPKGAPTPPAAT-PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSP--- 1305

Query: 343  HHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVS 402
               P  A     A  P P  +   P     P+ A T         PP + P  P K   +
Sbjct: 1306 ---PKGAPTPPAATPPSPKGSPGTPP----PKGAPT---------PPAVTPPSP-KGTPT 1348

Query: 403  LACDPASQQPGPLNGSGQ------LKMPSHCLSAQMLAPPP---PGLPR----------L 443
            L     S + GP   S +         PSH     M  P P   P +P           +
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVI 1408

Query: 444  ALPPATKPAT--TSEGGATSPTSPSYSPPDTSPAN 476
             L P   PAT  T EG AT P+    +PP  +P +
Sbjct: 1409 PLSPKKAPATPVTREGAAT-PSKGDLTPPAVTPVS 1442



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 58/203 (28%), Positives = 79/203 (38%), Gaps = 23/203 (11%)

Query: 293  SPSSP--TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAV 350
            +P SP  T +    T   +GG ++P  K E    P  +PS +  P ++  +    P I  
Sbjct: 1339 TPPSPKGTPTLPATTPSSKGGPTTPSSK-EGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397

Query: 351  HSGIARSPH--PSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 408
              G   SP   P S    P T +  + A+T  P      PP + P       VSL   PA
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAAT--PSKGDLTPPAVTP-------VSLKKAPA 1448

Query: 409  SQQP--GPLNGS--GQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTS 464
            +  P  GP   S  G   +P+         PP P     +  P   PAT +  GA  PT 
Sbjct: 1449 TSAPKGGPATPSSKGDPTLPA-VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGA--PTL 1505

Query: 465  PSYSPPDTSPANRSFVGLGPRDP 487
            P+  P  +SP          RDP
Sbjct: 1506 PAVIP--SSPKEVPATPSSRRDP 1526



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/192 (24%), Positives = 64/192 (33%), Gaps = 39/192 (20%)

Query: 313  SSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSIL 372
            ++P+ K          PSP+  P   S      P  A       SP    A   P  + +
Sbjct: 1049 ATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP----SPKGGPATPSPKGAPM 1104

Query: 373  PQTASTYFPHTAIRYPPH--------LNPQDPLKDLVS-----LACDPASQQPGPLNGSG 419
            P  A+   P   +  PPH          P  P   L +         PA+  P P  G  
Sbjct: 1105 PPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG-- 1162

Query: 420  QLKMPSHCLSAQMLAPPPPGLPRL--ALPPATKPATTSEGGATSPTSPSYSPPDTSPANR 477
                        +  PPP G P    A PP+ K    +     +PT+P+ +PP  SP   
Sbjct: 1163 ------------LATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKG- 1207

Query: 478  SFVGLGPRDPAG 489
               GL    P G
Sbjct: 1208 ---GLATPSPKG 1216



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 58/254 (22%), Positives = 82/254 (32%), Gaps = 55/254 (21%)

Query: 254  ASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSP---GGDYYTSPSSPTSSSRNWTEDMEG 310
            A T    T PS     +     G+      T P   GG    SP    ++        +G
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 311  GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIA----VHSGIARSPHPSSALHF 366
            G+++P  K          PSP+  P          P  A    +  G+A  PH  +    
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA---- 1286

Query: 367  PTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSH 426
                          P+ A+  PP                 PA+  P P    G       
Sbjct: 1287 --------------PNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG------- 1325

Query: 427  CLSAQMLAPPPPGLPRLALPPATK----------PATT--SEGGATSPTS-PSYSPPDTS 473
                    PPP G P    PPA            PATT  S+GG T+P+S    +PP  +
Sbjct: 1326 -------TPPPKGAPT---PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT 1375

Query: 474  PANRSFVGLGPRDP 487
            P+++    + P  P
Sbjct: 1376 PSHKGGPAMTPPSP 1389



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 57/232 (24%), Positives = 79/232 (34%), Gaps = 25/232 (10%)

Query: 264  STSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDK 323
            S +SS  K+ ++    + +  SP      +P + T  S       +GG ++P  K     
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP------KGGPATPSPKWAPTP 965

Query: 324  SPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTT-SILPQT-----AS 377
                 PSP+  P   S      P  A        P   S    PT  ++ P +     A+
Sbjct: 966  PAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025

Query: 378  TYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPP 437
            T FP  A   PP   P  P            S    PL   G    P+  L +    P  
Sbjct: 1026 TPFPKGAST-PPAATPPSP----------KGSPAATPLP-KGAPTTPAATLPSPKGGPAT 1073

Query: 438  PGLPRLALPPATKPATTSEGGAT-SPTSPSYSPPDTSPANRSFVGLGPRDPA 488
            P L     PPA  P +   G AT SP      P  T P+ +  +   P   A
Sbjct: 1074 PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 58/242 (23%), Positives = 85/242 (35%), Gaps = 52/242 (21%)

Query: 252  NPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
            +PA+T L +  P+T ++     K G     +  +P     T PS             +GG
Sbjct: 1046 SPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP------------KGG 1093

Query: 312  ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
             ++P  K     +P    +   SP+    T  H+   A  +  A  P P   L  P    
Sbjct: 1094 PATPSPKG----APMPPAATPPSPKGGLATPPHKG--APTTPAATPPSPKGGLATPPPKG 1147

Query: 372  LPQT--ASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLS 429
             P T  A+   P   +  PP   P+            PA+  P P  G            
Sbjct: 1148 APTTPAATPPSPKGGLATPP---PK-------GAPTTPAATPPSPKGG------------ 1185

Query: 430  AQMLAPPPPGLPRL--ALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDP 487
              +  P P G P    A PP+ K    +     +PT+P+ +PP  SP      GL    P
Sbjct: 1186 --LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP--SPKG----GLATPSP 1237

Query: 488  AG 489
             G
Sbjct: 1238 KG 1239



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 44/179 (24%), Positives = 59/179 (32%), Gaps = 23/179 (12%)

Query: 329  PSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT-TSILPQTASTYFPHTAIRY 387
            P+P+++P   S  +   P     S    +P P   L  P  TS  P+ A T  P      
Sbjct: 1565 PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPT--PPAVTPP 1622

Query: 388  PPHLNPQDP---------------LKDL----VSLACDPASQQPGPLNGSGQLKMPSHCL 428
             P   P  P               LKD      S+ C   +  P    G    K P+  L
Sbjct: 1623 SPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT-AL 1681

Query: 429  SAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDP 487
               ++AP P   P +  P    P T      + P  P  S  + S    S V   P  P
Sbjct: 1682 KEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLP 1740



 Score = 29.6 bits (65), Expect = 6.7
 Identities = 43/202 (21%), Positives = 74/202 (36%), Gaps = 25/202 (12%)

Query: 280  EDVDTSPGGDYYTSPSSPTSSSRN-WTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLS 338
            E   T   GD      +P S  +   T   +GG ++P  K +        PSP++ P   
Sbjct: 1423 EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK 1482

Query: 339  SFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLK 398
                     +A  S   ++P   + +  PT   +  ++    P T        + +DP+ 
Sbjct: 1483 Q--------VATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS------SRRDPIA 1528

Query: 399  DLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGG 458
               +L    + + P  L     L  P+      M  P P   P +  P    PAT S   
Sbjct: 1529 PTATLL---SKKTPATLAPKEALIPPA------MTVPSPKKTPAIPTPKEA-PATPSSKE 1578

Query: 459  ATSPTSPSYSPPDTSPANRSFV 480
            A+SP + + S    +P+ +  +
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELL 1600


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 64/247 (25%), Positives = 86/247 (34%), Gaps = 29/247 (11%)

Query: 261 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSP----- 315
           T   +S  G  RH S S E   D  PG      PSSP S S+ +  D      +P     
Sbjct: 690 TRQDSSLGGRARHMSSSQELLGDGPPG------PSSPMSRSQEYLLDEGPAPGTPPREAR 743

Query: 316 -------VKKTEMDKSPFNSPSPQDSPRLSSFTQHH-----RPVIAVHSGIARSPHPSSA 363
                  +K+  +   P   P     P  S FT        RP      G    P P++A
Sbjct: 744 PGRHGHSIKRASVPPVP-GKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATA 802

Query: 364 LHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKM 423
              PT  +LP T     P +  + P H      L   V     PA+  PGP        +
Sbjct: 803 KVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAA--PGPAPPPVPTAV 860

Query: 424 PSHCLSAQMLAPPPPGLPRLALPPATK-PATTSEGGATSPTSPSYSPPDTSPANRSFVGL 482
           P+ CL  +  A   PG P+       +  A+ SE        P+ + P  +   R     
Sbjct: 861 PTLCLPPE--ADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSH 918

Query: 483 GPRDPAG 489
             R PAG
Sbjct: 919 SVRAPAG 925



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 27/102 (26%), Positives = 37/102 (36%), Gaps = 8/102 (7%)

Query: 381  PHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNG----SGQLKMPSH--CLSAQMLA 434
            P  + + PP      P+K +  L    A   P P       +   K P     L A    
Sbjct: 1268 PPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAK 1327

Query: 435  PPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPAN 476
            PP PG P L +P   KP   +   A +  +P   P   SP +
Sbjct: 1328 PPSPGAPALHVP--AKPPRAAAAAAAAAAAPPAPPEGASPGD 1367



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 62/253 (24%), Positives = 82/253 (32%), Gaps = 29/253 (11%)

Query: 259  RRTL--PSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSP- 315
            RRTL  P T    + R   G   E  D  P  +  T    P   S+      E G+  P 
Sbjct: 1063 RRTLSGPVTGLLATARRGPG---ESADPGPFVEDGTGRQRPRGPSKG-----EAGVEGPP 1114

Query: 316  VKKTEMD-------KSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368
            + K E         ++  N           S T   RP           P P S  H  T
Sbjct: 1115 LAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGT 1174

Query: 369  TSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA----SQQPG--PLNGSGQLK 422
             ++  + AS       +  PP    + P  DL  L   P     +++P   P++    L 
Sbjct: 1175 GTVRRRPASEQAGPPELPPPPP-PAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLT 1233

Query: 423  MPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGL 482
             P   L       P P   ++ LP    P      G   P SP   PP T+P     V  
Sbjct: 1234 QPVPKLQGS----PTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAG 1289

Query: 483  GPRDPAGIYQAQS 495
             P   AG   A S
Sbjct: 1290 LPSGSAGPSPAPS 1302


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 62/299 (20%), Positives = 104/299 (34%), Gaps = 53/299 (17%)

Query: 202 LDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRT 261
           LD  DF+   VT+   S T+  +VS +P +T   P              +NP     R +
Sbjct: 92  LDNGDFK---VTTPDTSTTQHNKVSTSPKITTAKP--------------INP-----RPS 129

Query: 262 LPSTSSSGSKRHKSGSMEEDVDT-----------SPGGDYYTSPSSPTSSSRNWTEDMEG 310
           LP  S +  +   + + E  V+T           + G +  TS     S  +   +D+  
Sbjct: 130 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 189

Query: 311 GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 370
                 K T   ++    P+   +P+  + T    P     S   + P P++    PTT 
Sbjct: 190 TSKVLAKPTPKAETTTKGPA-LTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTP 244

Query: 371 ILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA 430
             P   +T    T  + P     ++P            +++P P                
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS----------- 293

Query: 431 QMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSFVGLGPRDPA 488
              AP  P  P    P    P T  E   T+P  P+  +P + +P  +      P++PA
Sbjct: 294 ---APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 349



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/234 (19%), Positives = 79/234 (33%), Gaps = 12/234 (5%)

Query: 261 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTE 320
           T P   +  + +  + + +E   T+P     T+P  P  ++            +P    E
Sbjct: 320 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 379

Query: 321 MDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIA-RSPHPSSALH-FPTTSILPQTAST 378
              +    P+P  +    + T+   P     +    + P P++     PTT   P   + 
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439

Query: 379 YFPH-TAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA---QMLA 434
             P  T  + P    P++P             ++P P             L+    + LA
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499

Query: 435 PPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPA 488
           P  P  P    P    P T  E   T+P  P+ + P  +  N       P++PA
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPA 547



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/230 (19%), Positives = 79/230 (34%), Gaps = 23/230 (10%)

Query: 253 PASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
           PA T  ++  P   + + +K   S + ++   T+P G   T+P  P  ++          
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-------- 637

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
              P   T    +P     P  +       +   P          S  P+      T   
Sbjct: 638 --EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 695

Query: 372 LPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQ 431
            P+  +   P    + P    P+ P      ++    +++P  ++ S     P   LSA+
Sbjct: 696 TPKEPAPTTP----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE--LSAE 749

Query: 432 ML------APPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
                   +P  PG+P    P ATKP  T+     +      + P+T+ A
Sbjct: 750 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 799



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 46/249 (18%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP----TSSSRNWTEDM 308
           PA T  ++  P+T     K     + +E   T+      T+P  P    T S+   T++ 
Sbjct: 348 PAPTAPKKPAPTTP----KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 403

Query: 309 EGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALH-F 366
               +     T  + SP  +  P  + P+  + T   +P         + P P++     
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPA 459

Query: 367 PTTSILP------QTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420
           PTT+  P      + A T    TA   P  L P  P K   +    PA   P        
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------- 511

Query: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSF 479
                     + LAP  P  P    P    P T       +P  P+  +P + +P     
Sbjct: 512 ----------EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT--- 558

Query: 480 VGLGPRDPA 488
               P++PA
Sbjct: 559 ----PKEPA 563



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 48/233 (20%), Positives = 78/233 (33%), Gaps = 36/233 (15%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 312
           P  T      P+T  + +      + +E   T+P     T+P  P  ++   T       
Sbjct: 522 PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 577

Query: 313 SSPVKKTEMDKSPFNSPSPQD----SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368
           ++P    E   +    P+P++    + +  + T   +P      G A +     A   PT
Sbjct: 578 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PT 634

Query: 369 TSILPQ-TASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHC 427
           T   P  T       T ++ P    P+ P           A ++  P    G     S  
Sbjct: 635 TPKEPAPTTPKGTAPTTLKEPAPTTPKKP-----------APKELAPTTTKGPTSTTSD- 682

Query: 428 LSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480
                   P P  P+      T P T  E   T+P  P+ + P+T P   S V
Sbjct: 683 -------KPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 723


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 62/299 (20%), Positives = 104/299 (34%), Gaps = 53/299 (17%)

Query: 202 LDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRT 261
           LD  DF+   VT+   S T+  +VS +P +T   P              +NP     R +
Sbjct: 133 LDNGDFK---VTTPDTSTTQHNKVSTSPKITTAKP--------------INP-----RPS 170

Query: 262 LPSTSSSGSKRHKSGSMEEDVDT-----------SPGGDYYTSPSSPTSSSRNWTEDMEG 310
           LP  S +  +   + + E  V+T           + G +  TS     S  +   +D+  
Sbjct: 171 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 230

Query: 311 GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 370
                 K T   ++    P+   +P+  + T    P     S   + P P++    PTT 
Sbjct: 231 TSKVLAKPTPKAETTTKGPA-LTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTP 285

Query: 371 ILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA 430
             P   +T    T  + P     ++P            +++P P                
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS----------- 334

Query: 431 QMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSFVGLGPRDPA 488
              AP  P  P    P    P T  E   T+P  P+  +P + +P  +      P++PA
Sbjct: 335 ---APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 390



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/234 (19%), Positives = 79/234 (33%), Gaps = 12/234 (5%)

Query: 261 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTE 320
           T P   +  + +  + + +E   T+P     T+P  P  ++            +P    E
Sbjct: 361 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 420

Query: 321 MDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIA-RSPHPSSALH-FPTTSILPQTAST 378
              +    P+P  +    + T+   P     +    + P P++     PTT   P   + 
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480

Query: 379 YFPH-TAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA---QMLA 434
             P  T  + P    P++P             ++P P             L+    + LA
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540

Query: 435 PPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPA 488
           P  P  P    P    P T  E   T+P  P+ + P  +  N       P++PA
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPA 588



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/230 (19%), Positives = 79/230 (34%), Gaps = 23/230 (10%)

Query: 253 PASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
           PA T  ++  P   + + +K   S + ++   T+P G   T+P  P  ++          
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-------- 678

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
              P   T    +P     P  +       +   P          S  P+      T   
Sbjct: 679 --EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 736

Query: 372 LPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQ 431
            P+  +   P    + P    P+ P      ++    +++P  ++ S     P   LSA+
Sbjct: 737 TPKEPAPTTP----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE--LSAE 790

Query: 432 ML------APPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
                   +P  PG+P    P ATKP  T+     +      + P+T+ A
Sbjct: 791 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 840



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 46/249 (18%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP----TSSSRNWTEDM 308
           PA T  ++  P+T     K     + +E   T+      T+P  P    T S+   T++ 
Sbjct: 389 PAPTAPKKPAPTTP----KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 444

Query: 309 EGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALH-F 366
               +     T  + SP  +  P  + P+  + T   +P         + P P++     
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPA 500

Query: 367 PTTSILP------QTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420
           PTT+  P      + A T    TA   P  L P  P K   +    PA   P        
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------- 552

Query: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSF 479
                     + LAP  P  P    P    P T       +P  P+  +P + +P     
Sbjct: 553 ----------EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT--- 599

Query: 480 VGLGPRDPA 488
               P++PA
Sbjct: 600 ----PKEPA 604



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 48/233 (20%), Positives = 78/233 (33%), Gaps = 36/233 (15%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 312
           P  T      P+T  + +      + +E   T+P     T+P  P  ++   T       
Sbjct: 563 PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 618

Query: 313 SSPVKKTEMDKSPFNSPSPQD----SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368
           ++P    E   +    P+P++    + +  + T   +P      G A +     A   PT
Sbjct: 619 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PT 675

Query: 369 TSILPQ-TASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHC 427
           T   P  T       T ++ P    P+ P           A ++  P    G     S  
Sbjct: 676 TPKEPAPTTPKGTAPTTLKEPAPTTPKKP-----------APKELAPTTTKGPTSTTSD- 723

Query: 428 LSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480
                   P P  P+      T P T  E   T+P  P+ + P+T P   S V
Sbjct: 724 -------KPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 764


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 62/299 (20%), Positives = 104/299 (34%), Gaps = 53/299 (17%)

Query: 202 LDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRT 261
           LD  DF+   VT+   S T+  +VS +P +T   P              +NP     R +
Sbjct: 185 LDNGDFK---VTTPDTSTTQHNKVSTSPKITTAKP--------------INP-----RPS 222

Query: 262 LPSTSSSGSKRHKSGSMEEDVDT-----------SPGGDYYTSPSSPTSSSRNWTEDMEG 310
           LP  S +  +   + + E  V+T           + G +  TS     S  +   +D+  
Sbjct: 223 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 282

Query: 311 GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 370
                 K T   ++    P+   +P+  + T    P     S   + P P++    PTT 
Sbjct: 283 TSKVLAKPTPKAETTTKGPA-LTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTP 337

Query: 371 ILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA 430
             P   +T    T  + P     ++P            +++P P                
Sbjct: 338 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS----------- 386

Query: 431 QMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSFVGLGPRDPA 488
              AP  P  P    P    P T  E   T+P  P+  +P + +P  +      P++PA
Sbjct: 387 ---APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 442



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/234 (19%), Positives = 79/234 (33%), Gaps = 12/234 (5%)

Query: 261 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTE 320
           T P   +  + +  + + +E   T+P     T+P  P  ++            +P    E
Sbjct: 413 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472

Query: 321 MDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIA-RSPHPSSALH-FPTTSILPQTAST 378
              +    P+P  +    + T+   P     +    + P P++     PTT   P   + 
Sbjct: 473 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 532

Query: 379 YFPH-TAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA---QMLA 434
             P  T  + P    P++P             ++P P             L+    + LA
Sbjct: 533 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592

Query: 435 PPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPA 488
           P  P  P    P    P T  E   T+P  P+ + P  +  N       P++PA
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPA 640



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/230 (19%), Positives = 79/230 (34%), Gaps = 23/230 (10%)

Query: 253 PASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
           PA T  ++  P   + + +K   S + ++   T+P G   T+P  P  ++          
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-------- 730

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
              P   T    +P     P  +       +   P          S  P+      T   
Sbjct: 731 --EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 788

Query: 372 LPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQ 431
            P+  +   P    + P    P+ P      ++    +++P  ++ S     P   LSA+
Sbjct: 789 TPKEPAPTTP----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE--LSAE 842

Query: 432 ML------APPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
                   +P  PG+P    P ATKP  T+     +      + P+T+ A
Sbjct: 843 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 892



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 46/249 (18%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP----TSSSRNWTEDM 308
           PA T  ++  P+T     K     + +E   T+      T+P  P    T S+   T++ 
Sbjct: 441 PAPTAPKKPAPTTP----KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 496

Query: 309 EGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALH-F 366
               +     T  + SP  +  P  + P+  + T   +P         + P P++     
Sbjct: 497 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPA 552

Query: 367 PTTSILP------QTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420
           PTT+  P      + A T    TA   P  L P  P K   +    PA   P        
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------- 604

Query: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSF 479
                     + LAP  P  P    P    P T       +P  P+  +P + +P     
Sbjct: 605 ----------EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT--- 651

Query: 480 VGLGPRDPA 488
               P++PA
Sbjct: 652 ----PKEPA 656



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 48/233 (20%), Positives = 78/233 (33%), Gaps = 36/233 (15%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 312
           P  T      P+T  + +      + +E   T+P     T+P  P  ++   T       
Sbjct: 615 PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 670

Query: 313 SSPVKKTEMDKSPFNSPSPQD----SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368
           ++P    E   +    P+P++    + +  + T   +P      G A +     A   PT
Sbjct: 671 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PT 727

Query: 369 TSILPQ-TASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHC 427
           T   P  T       T ++ P    P+ P           A ++  P    G     S  
Sbjct: 728 TPKEPAPTTPKGTAPTTLKEPAPTTPKKP-----------APKELAPTTTKGPTSTTSD- 775

Query: 428 LSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480
                   P P  P+      T P T  E   T+P  P+ + P+T P   S V
Sbjct: 776 -------KPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 816


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 62/299 (20%), Positives = 104/299 (34%), Gaps = 53/299 (17%)

Query: 202 LDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRT 261
           LD  DF+   VT+   S T+  +VS +P +T   P              +NP     R +
Sbjct: 226 LDNGDFK---VTTPDTSTTQHNKVSTSPKITTAKP--------------INP-----RPS 263

Query: 262 LPSTSSSGSKRHKSGSMEEDVDT-----------SPGGDYYTSPSSPTSSSRNWTEDMEG 310
           LP  S +  +   + + E  V+T           + G +  TS     S  +   +D+  
Sbjct: 264 LPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP 323

Query: 311 GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 370
                 K T   ++    P+   +P+  + T    P     S   + P P++    PTT 
Sbjct: 324 TSKVLAKPTPKAETTTKGPA-LTTPKEPTPTTPKEPA----STTPKEPTPTTIKSAPTTP 378

Query: 371 ILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA 430
             P   +T    T  + P     ++P            +++P P                
Sbjct: 379 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS----------- 427

Query: 431 QMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSFVGLGPRDPA 488
              AP  P  P    P    P T  E   T+P  P+  +P + +P  +      P++PA
Sbjct: 428 ---APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA 483



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/234 (19%), Positives = 79/234 (33%), Gaps = 12/234 (5%)

Query: 261 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTE 320
           T P   +  + +  + + +E   T+P     T+P  P  ++            +P    E
Sbjct: 454 TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513

Query: 321 MDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIA-RSPHPSSALH-FPTTSILPQTAST 378
              +    P+P  +    + T+   P     +    + P P++     PTT   P   + 
Sbjct: 514 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 573

Query: 379 YFPH-TAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSA---QMLA 434
             P  T  + P    P++P             ++P P             L+    + LA
Sbjct: 574 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633

Query: 435 PPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFVGLGPRDPA 488
           P  P  P    P    P T  E   T+P  P+ + P  +  N       P++PA
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPA 681



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 44/230 (19%), Positives = 79/230 (34%), Gaps = 23/230 (10%)

Query: 253 PASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGG 311
           PA T  ++  P   + + +K   S + ++   T+P G   T+P  P  ++          
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPK-------- 771

Query: 312 ISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
              P   T    +P     P  +       +   P          S  P+      T   
Sbjct: 772 --EPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPT 829

Query: 372 LPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHCLSAQ 431
            P+  +   P    + P    P+ P      ++    +++P  ++ S     P   LSA+
Sbjct: 830 TPKEPAPTTP----KKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE--LSAE 883

Query: 432 ML------APPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPA 475
                   +P  PG+P    P ATKP  T+     +      + P+T+ A
Sbjct: 884 PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA 933



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 54/249 (21%), Positives = 85/249 (34%), Gaps = 46/249 (18%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP----TSSSRNWTEDM 308
           PA T  ++  P+T     K     + +E   T+      T+P  P    T S+   T++ 
Sbjct: 482 PAPTAPKKPAPTTP----KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP 537

Query: 309 EGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALH-F 366
               +     T  + SP  +  P  + P+  + T   +P         + P P++     
Sbjct: 538 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT----PKEPAPTTPKEPA 593

Query: 367 PTTSILP------QTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQ 420
           PTT+  P      + A T    TA   P  L P  P K   +    PA   P        
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTP-------- 645

Query: 421 LKMPSHCLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPS-YSPPDTSPANRSF 479
                     + LAP  P  P    P    P T       +P  P+  +P + +P     
Sbjct: 646 ----------EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT--- 692

Query: 480 VGLGPRDPA 488
               P++PA
Sbjct: 693 ----PKEPA 697



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 48/233 (20%), Positives = 78/233 (33%), Gaps = 36/233 (15%)

Query: 253 PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 312
           P  T      P+T  + +      + +E   T+P     T+P  P  ++   T       
Sbjct: 656 PTPTTPEEPAPTTPKAAAPN----TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG 711

Query: 313 SSPVKKTEMDKSPFNSPSPQD----SPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPT 368
           ++P    E   +    P+P++    + +  + T   +P      G A +     A   PT
Sbjct: 712 TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA---PT 768

Query: 369 TSILPQ-TASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSHC 427
           T   P  T       T ++ P    P+ P           A ++  P    G     S  
Sbjct: 769 TPKEPAPTTPKGTAPTTLKEPAPTTPKKP-----------APKELAPTTTKGPTSTTSD- 816

Query: 428 LSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPANRSFV 480
                   P P  P+      T P T  E   T+P  P+ + P+T P   S V
Sbjct: 817 -------KPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV 857


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 53/230 (23%), Positives = 82/230 (35%), Gaps = 27/230 (11%)

Query: 262 LPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVK---- 317
           +P   S+ ++ + SG     +    G      P SP S    +     G  S P +    
Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167

Query: 318 -----KTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
                + ++   P + P P  S PR    + H+R    V  G  R P P      PT   
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG-PRQPSPG-----PTPPP 221

Query: 372 LPQTASTYFPHTAIRYPP-----HLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSH 426
            P    T     +IR  P       + + PL    S A D     P P  G+     PS 
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGN----RPS- 276

Query: 427 CLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPAN 476
            +  + + PPPP   +  +P   +P+ +S+     P      PP   P++
Sbjct: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 53/230 (23%), Positives = 82/230 (35%), Gaps = 27/230 (11%)

Query: 262 LPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVK---- 317
           +P   S+ ++ + SG     +    G      P SP S    +     G  S P +    
Sbjct: 108 MPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRN 167

Query: 318 -----KTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 371
                + ++   P + P P  S PR    + H+R    V  G  R P P      PT   
Sbjct: 168 RMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGG-PRQPSPG-----PTPPP 221

Query: 372 LPQTASTYFPHTAIRYPP-----HLNPQDPLKDLVSLACDPASQQPGPLNGSGQLKMPSH 426
            P    T     +IR  P       + + PL    S A D     P P  G+     PS 
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGN----RPS- 276

Query: 427 CLSAQMLAPPPPGLPRLALPPATKPATTSEGGATSPTSPSYSPPDTSPAN 476
            +  + + PPPP   +  +P   +P+ +S+     P      PP   P++
Sbjct: 277 -IHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,173,167
Number of Sequences: 37866
Number of extensions: 1423546
Number of successful extensions: 9263
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 6890
Number of HSP's gapped (non-prelim): 2073
length of query: 499
length of database: 18,247,518
effective HSP length: 106
effective length of query: 393
effective length of database: 14,233,722
effective search space: 5593852746
effective search space used: 5593852746
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.