Guide to the Human Genome
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Search of human proteins with 45505149

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
         (428 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]               877   0.0  
gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]               844   0.0  
gi|93004092 nuclear factor I/B [Homo sapiens]                         528   e-150
gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]              512   e-145
gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]               512   e-145
gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]              512   e-145
gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]              497   e-141
gi|56549649 nuclear factor I/X (CCAAT-binding transcription fact...   473   e-133
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             42   8e-04
gi|4503493 early growth response 1 [Homo sapiens]                      40   0.003
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  39   0.009
gi|217416343 fibrosin-like 1 [Homo sapiens]                            38   0.015
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    38   0.020
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    38   0.020
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]             37   0.034
gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]             37   0.034
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        37   0.045
gi|148236531 hypothetical protein LOC339779 [Homo sapiens]             37   0.045
gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]    36   0.059
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    35   0.100
gi|167736355 mucin 4 isoform a [Homo sapiens]                          35   0.13 
gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]       35   0.17 
gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]       35   0.17 
gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]       35   0.17 
gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]        35   0.17 
gi|26667257 eyes absent 4 isoform d [Homo sapiens]                     35   0.17 
gi|98991760 eyes absent 4 isoform a [Homo sapiens]                     35   0.17 
gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]              35   0.17 
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ...    35   0.17 
gi|215422375 neural precursor cell expressed, developmentally do...    34   0.22 

>gi|45505149 nuclear factor I/C isoform 1 [Homo sapiens]
          Length = 428

 Score =  877 bits (2266), Expect = 0.0
 Identities = 428/428 (100%), Positives = 428/428 (100%)

Query: 1   MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60
           MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE
Sbjct: 1   MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60

Query: 61  LLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDC 120
           LLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDC
Sbjct: 61  LLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDC 120

Query: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYL 180
           LRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYL
Sbjct: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYL 180

Query: 181 AYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVV 240
           AYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVV
Sbjct: 181 AYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVV 240

Query: 241 TGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYY 300
           TGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYY
Sbjct: 241 TGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYY 300

Query: 301 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVH 360
           TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVH
Sbjct: 301 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVH 360

Query: 361 SGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQ 420
           SGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQ
Sbjct: 361 SGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQ 420

Query: 421 PGPSWYLG 428
           PGPSWYLG
Sbjct: 421 PGPSWYLG 428


>gi|45505151 nuclear factor I/C isoform 2 [Homo sapiens]
          Length = 499

 Score =  844 bits (2180), Expect = 0.0
 Identities = 413/413 (100%), Positives = 413/413 (100%)

Query: 11  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 70
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 61

Query: 71  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 130
           KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 131 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 190
           DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 181

Query: 191 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 250
           QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG
Sbjct: 182 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 241

Query: 251 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 310
           ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS
Sbjct: 242 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSS 301

Query: 311 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS 370
           RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS
Sbjct: 302 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPS 361

Query: 371 SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 423
           SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP
Sbjct: 362 SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 414


>gi|93004092 nuclear factor I/B [Homo sapiens]
          Length = 420

 Score =  528 bits (1361), Expect = e-150
 Identities = 280/432 (64%), Positives = 329/432 (76%), Gaps = 16/432 (3%)

Query: 1   MYSSPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60
           M  SP+CLTQDEFHPFIEALLPHVRA AYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE
Sbjct: 1   MMYSPICLTQDEFHPFIEALLPHVRAIAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDE 60

Query: 61  LLGEKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDC 120
           LL EKPE+KQKWASRLLAKLRKDIR E REDFVL++TGKK P CVLSNPDQKGK+RRIDC
Sbjct: 61  LLSEKPEIKQKWASRLLAKLRKDIRQEYREDFVLTVTGKKHPCCVLSNPDQKGKIRRIDC 120

Query: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYL 180
           LRQADKVWRLDLVMVILFKGIPLESTDGERL+K+  C +P LCVQPHHI V+VKELDL+L
Sbjct: 121 LRQADKVWRLDLVMVILFKGIPLESTDGERLMKSPHCTNPALCVQPHHITVSVKELDLFL 180

Query: 181 AYFVRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVV 240
           AY+V+E+D+ QSGSP     +D   + P  L     ++SFV SGVF+V+EL++VSRTP+ 
Sbjct: 181 AYYVQEQDSGQSGSP---SHNDPAKNPPGYL-----EDSFVKSGVFNVSELVRVSRTPIT 232

Query: 241 TGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYY 300
            GTG NF +GE+     Y    +   L+R+L S  S  SKR K+ S++E+++ SP GD+Y
Sbjct: 233 QGTGVNFPIGEIPSQPYYHDMNSGVNLQRSLSSPPS--SKRPKTISIDENMEPSPTGDFY 290

Query: 301 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQD-SPRLSSFTQHHRPVI-- 357
            SPSSP + SR W E  +  +SSP    + +K  F+S SPQD SPRLS+F QHH P I  
Sbjct: 291 PSPSSPAAGSRTWHE-RDQDMSSPTTMKKPEKPLFSSASPQDSSPRLSTFPQHHHPGIPG 349

Query: 358 AVHSGIA-RSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDP 416
             HS I+ R+P P S L FPT +ILP   S+YF H  IRYPPHLNPQD LK+ V  + DP
Sbjct: 350 VAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVP-SYDP 408

Query: 417 ASQQPGPSWYLG 428
           +S Q   SWYLG
Sbjct: 409 SSPQTSQSWYLG 420


>gi|224465184 nuclear factor I/A isoform 4 [Homo sapiens]
          Length = 554

 Score =  512 bits (1318), Expect = e-145
 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%)

Query: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63
           SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL 
Sbjct: 48  SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 107

Query: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123
           EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ
Sbjct: 108 EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 167

Query: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183
           ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF
Sbjct: 168 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 227

Query: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243
           V   D+ QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GT
Sbjct: 228 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 285

Query: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301
           GPNFSL +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT  
Sbjct: 286 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 342

Query: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358
             SP S + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI 
Sbjct: 343 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 399

Query: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417
             +G   SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A
Sbjct: 400 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 452

Query: 418 SQQPGPSWYL 427
            QQ G   +L
Sbjct: 453 GQQAGQVGFL 462


>gi|30840980 nuclear factor I/A isoform 2 [Homo sapiens]
          Length = 498

 Score =  512 bits (1318), Expect = e-145
 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%)

Query: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63
           SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL 
Sbjct: 3   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 62

Query: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123
           EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ
Sbjct: 63  EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 122

Query: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183
           ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF
Sbjct: 123 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 182

Query: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243
           V   D+ QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GT
Sbjct: 183 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301
           GPNFSL +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT  
Sbjct: 241 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 297

Query: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358
             SP S + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI 
Sbjct: 298 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 354

Query: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417
             +G   SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A
Sbjct: 355 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 407

Query: 418 SQQPGPSWYL 427
            QQ G   +L
Sbjct: 408 GQQAGQVGFL 417


>gi|197927284 nuclear factor I/A isoform 1 [Homo sapiens]
          Length = 509

 Score =  512 bits (1318), Expect = e-145
 Identities = 278/430 (64%), Positives = 325/430 (75%), Gaps = 21/430 (4%)

Query: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63
           SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL 
Sbjct: 3   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLS 62

Query: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123
           EKPEVKQKWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQ
Sbjct: 63  EKPEVKQKWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQ 122

Query: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183
           ADKVWRLDLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYF
Sbjct: 123 ADKVWRLDLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYF 182

Query: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243
           V   D+ QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GT
Sbjct: 183 VHAADSSQSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGT 240

Query: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT-- 301
           GPNFSL +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT  
Sbjct: 241 GPNFSLSDLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQ 297

Query: 302 --SPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIA 358
             SP S + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI 
Sbjct: 298 GRSPGSGSQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI- 354

Query: 359 VHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPA 417
             +G   SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A
Sbjct: 355 --TGPRASPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDA 407

Query: 418 SQQPGPSWYL 427
            QQ G   +L
Sbjct: 408 GQQAGQVGFL 417


>gi|224465182 nuclear factor I/A isoform 3 [Homo sapiens]
          Length = 501

 Score =  497 bits (1280), Expect = e-141
 Identities = 271/423 (64%), Positives = 318/423 (75%), Gaps = 21/423 (4%)

Query: 11  DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLGEKPEVKQ 70
           DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSK+EERAVKDELL EKPEVKQ
Sbjct: 2   DEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKEEERAVKDELLSEKPEVKQ 61

Query: 71  KWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQADKVWRL 130
           KWASRLLAKLRKDIRPE REDFVL++TGKK P CVLSNPDQKGKMRRIDCLRQADKVWRL
Sbjct: 62  KWASRLLAKLRKDIRPEYREDFVLTVTGKKPPCCVLSNPDQKGKMRRIDCLRQADKVWRL 121

Query: 131 DLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYFVRERDAE 190
           DLVMVILFKGIPLESTDGERLVK+ QC +P LCVQPHHIGV+VKELDLYLAYFV   D+ 
Sbjct: 122 DLVMVILFKGIPLESTDGERLVKSPQCSNPGLCVQPHHIGVSVKELDLYLAYFVHAADSS 181

Query: 191 QSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLG 250
           QS SP     +D +D          FQ+SFVTSGVFSVTEL++VS+TP+  GTGPNFSL 
Sbjct: 182 QSESPSQPSDADIKDQP--ENGHLGFQDSFVTSGVFSVTELVRVSQTPIAAGTGPNFSLS 239

Query: 251 ELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYT----SPSSP 306
           +L+    Y ++P +  +RR+LPSTSS+ S + +  S+E+++D+     +YT    SP S 
Sbjct: 240 DLESSSYYSMSPGA--MRRSLPSTSSTSSTK-RLKSVEDEMDSPGEEPFYTGQGRSPGSG 296

Query: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL-SSFTQHHRPVIAVHSGIAR 365
           + SS  W E +E G+ SP    + +KS F+SPSP  +  L ++FTQHHRPVI   +G   
Sbjct: 297 SQSS-GWHE-VEPGMPSPTTLKKSEKSGFSSPSPSQTSSLGTAFTQHHRPVI---TGPRA 351

Query: 366 SPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGPS 424
           SPH + S LHFPT+ I+ Q    YF H AIRY    +PQ+ LK+ V L C  A QQ G  
Sbjct: 352 SPHATPSTLHFPTSPII-QQPGPYFSHPAIRY----HPQETLKEFVQLVCPDAGQQAGQV 406

Query: 425 WYL 427
            +L
Sbjct: 407 GFL 409


>gi|56549649 nuclear factor I/X (CCAAT-binding transcription factor)
           [Homo sapiens]
          Length = 441

 Score =  473 bits (1216), Expect = e-133
 Identities = 260/421 (61%), Positives = 302/421 (71%), Gaps = 13/421 (3%)

Query: 4   SPLCLTQDEFHPFIEALLPHVRAFAYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 63
           SP CLTQDEFHPFIEALLPHVRAF+YTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG
Sbjct: 3   SPYCLTQDEFHPFIEALLPHVRAFSYTWFNLQARKRKYFKKHEKRMSKDEERAVKDELLG 62

Query: 64  EKPEVKQKWASRLLAKLRKDIRPECREDFVLSITGKKAPGCVLSNPDQKGKMRRIDCLRQ 123
           EKPE+KQKWASRLLAKLRKDIRPE REDFVL+ITGKK P CVLSNPDQKGK+RRIDCLRQ
Sbjct: 63  EKPEIKQKWASRLLAKLRKDIRPEFREDFVLTITGKKPPCCVLSNPDQKGKIRRIDCLRQ 122

Query: 124 ADKVWRLDLVMVILFKGIPLESTDGERLVKAAQCGHPVLCVQPHHIGVAVKELDLYLAYF 183
           ADKVWRLDLVMVILFKGIPLESTDGERL K+ QC +P LCVQPHHIGV +KELDLYLAYF
Sbjct: 123 ADKVWRLDLVMVILFKGIPLESTDGERLYKSPQCSNPGLCVQPHHIGVTIKELDLYLAYF 182

Query: 184 VRERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT 243
           V   ++ QS S          D KP+      FQ+ FVTSGV++VTEL++VS+TPV T +
Sbjct: 183 VHTPESGQSDSSNQ---QGDADIKPLPNGHLSFQDCFVTSGVWNVTELVRVSQTPVATAS 239

Query: 244 GPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS---GSMEEDVDTSPGGDYY 300
           GPNFSL +L+    Y++N  + G R      S+S +KR KS     ME  VD        
Sbjct: 240 GPNFSLADLESPSYYNINQVTLGRRSITSPPSTSTTKRPKSIDDSEMESPVDDVFYPGTG 299

Query: 301 TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIA-V 359
            SP++ +S S  W  D++ G +S  K  ++D     S S   SPR+ +FT H  PV+A V
Sbjct: 300 RSPAAGSSQSSGWPNDVDAGPASLKKSGKLDFCSALS-SQGSSPRM-AFTHHPLPVLAGV 357

Query: 360 HSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQ 419
             G  R+   +SALHFP+TSI+ Q +S YF H  IRY  H + QD LK+ V   C   S 
Sbjct: 358 RPGSPRA--TASALHFPSTSII-QQSSPYFTHPTIRYHHH-HGQDSLKEFVQFVCSDGSG 413

Query: 420 Q 420
           Q
Sbjct: 414 Q 414


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 58/211 (27%), Positives = 80/211 (37%), Gaps = 15/211 (7%)

Query: 222  TSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPS---TSSSG 278
            TS  +S T       +P  + T P++S        +   +P S     T PS   TS S 
Sbjct: 1625 TSPSYSPTSPNYSPTSPSYSPTSPSYS------PTSPSYSPTSPSYSPTSPSYSPTSPSY 1678

Query: 279  SKRHKSGSMEEDVDTSPGGDYY--TSPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPF 335
            S    S S       SP    Y  TSPS SPTS S + T       S     T    SP 
Sbjct: 1679 SPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1737

Query: 336  NSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIR 395
            +      SP  S  + ++ P    +S  + S  P+S  + PT+     T+ +Y P +   
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSY 1797

Query: 396  YP--PHLNPQDPLKDLVSLACDPASQQPGPS 424
             P  P  +P  P     S    P+S    PS
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPS 1828



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/134 (28%), Positives = 53/134 (39%), Gaps = 3/134 (2%)

Query: 294  SPGGDYYTSPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQH 352
            SPGG    SPS SPTS S + T       S     T    SP +      SP  S  +  
Sbjct: 1604 SPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1663

Query: 353  HRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYP--PHLNPQDPLKDLV 410
            + P    +S  + S  P+S  + PT+     T+ +Y P +    P  P  +P  P     
Sbjct: 1664 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1723

Query: 411  SLACDPASQQPGPS 424
            S +  P S    P+
Sbjct: 1724 SPSYSPTSPSYSPT 1737



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 47/180 (26%), Positives = 70/180 (38%), Gaps = 15/180 (8%)

Query: 222  TSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKR 281
            TS  +S T       +P  T T PN+S        +   +P S     T PS S S  + 
Sbjct: 1758 TSPSYSPTSPSYSPTSPNYTPTSPNYS------PTSPSYSPTSPSYSPTSPSYSPSSPRY 1811

Query: 282  HKSGSMEEDVDTSPGGDYYT--SPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSP 338
                   +    +P    Y+  SPS SPTS     T       S     T    SP +  
Sbjct: 1812 -----TPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPK 1866

Query: 339  SPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPP 398
                SP+ S  +  + P    +S  + +  P+S ++ PT+     T+ TY P T+ +Y P
Sbjct: 1867 YSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSP-TSPKYSP 1925



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 56/209 (26%), Positives = 78/209 (37%), Gaps = 18/209 (8%)

Query: 222  TSGVFSVTELIQVSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPS---TSSSG 278
            TS  +S T       +P  + T P++S        +   +P S     T PS   TS S 
Sbjct: 1681 TSPSYSPTSPSYSPTSPSYSPTSPSYS------PTSPSYSPTSPSYSPTSPSYSPTSPSY 1734

Query: 279  SKRHKSGSMEEDVDTSPGGDYYT--SPS-SPTSSSRNWTEDMEGGISSPVKKTEMDKSPF 335
            S    S S     + SP    YT  SPS SPTS S + T       S     T    SP 
Sbjct: 1735 SPTSPSYSPTSP-NYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT 1793

Query: 336  NSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIR 395
            +      SP  S  +  + P    ++  + S  PSS  + PT+     T+ +Y P +   
Sbjct: 1794 SPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSS--- 1850

Query: 396  YPPHLNPQDPLKDLVSLACDPASQQPGPS 424
              P   P  P     S    P S +  P+
Sbjct: 1851 --PEYTPTSPKYSPTSPKYSPTSPKYSPT 1877



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 45/167 (26%), Positives = 64/167 (38%), Gaps = 6/167 (3%)

Query: 261  NPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPS-SPTSSSRNWTEDMEG 319
            +P S     T PS S +    + S +      TSP     TSPS SPTS S + T     
Sbjct: 1616 SPTSPSYSPTSPSYSPTSP--NYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYS 1672

Query: 320  GISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTS 379
              S     T    SP +      SP  S  +  + P    +S  + S  P+S  + PT+ 
Sbjct: 1673 PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1732

Query: 380  ILPQTASTYFPHTAIRYP--PHLNPQDPLKDLVSLACDPASQQPGPS 424
                T+ +Y P +    P  P+  P  P     S +  P S    P+
Sbjct: 1733 SYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPT 1779


>gi|4503493 early growth response 1 [Homo sapiens]
          Length = 543

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 8/103 (7%)

Query: 305 SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIA 364
           +P S +  W E +   +S  V  T    S  ++PSP  S   S+      P+        
Sbjct: 142 APNSGNTLWPEPLFSLVSGLVSMTNPPASSSSAPSPAAS---SASASQSPPLSCAVPSND 198

Query: 365 RSPHPSSALHFPT--TSILPQTASTYFP---HTAIRYPPHLNP 402
            SP  S+A  FPT  T I P+  S  FP    TA++YPP   P
Sbjct: 199 SSPIYSAAPTFPTPNTDIFPEPQSQAFPGSAGTALQYPPPAYP 241


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 46/171 (26%), Positives = 59/171 (34%), Gaps = 24/171 (14%)

Query: 270 TLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSP----- 324
           T   +S  G  RH S S E   D  PG      PSSP S S+ +  D      +P     
Sbjct: 690 TRQDSSLGGRARHMSSSQELLGDGPPG------PSSPMSRSQEYLLDEGPAPGTPPREAR 743

Query: 325 -------VKKTEMDKSPFNSPSPQDSPRLSSFTQHH-----RPVIAVHSGIARSPHPSSA 372
                  +K+  +   P   P     P  S FT        RP      G    P P++A
Sbjct: 744 PGRHGHSIKRASVPPVP-GKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGPAPATA 802

Query: 373 LHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACDPASQQPGP 423
              PT  +LP T     P +  + P H      L   V     PA+  P P
Sbjct: 803 KVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPAP 853


>gi|217416343 fibrosin-like 1 [Homo sapiens]
          Length = 1045

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 41/157 (26%), Positives = 56/157 (35%), Gaps = 9/157 (5%)

Query: 254 GHLAYDLNPASTGLRRT-LPSTSSSGSKRHKSGSMEEDVDT----SPGGDYYTSPSSPTS 308
           G    DL PA  G R+  L  +        K G  + D D+    +   D  +  S+   
Sbjct: 140 GSPGQDLEPACDGARKVPLQPSKQMKVTVSKGGDRDSDDDSVLEATSSRDPLSDSSAHAV 199

Query: 309 SSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPH 368
           S R ++ D E G   P  K  +      +P     P L        PV  V SG+ RS  
Sbjct: 200 SGRGYSCDSESG---PDDKASVGSEKLFAPGTDKGPALEKSEAKAGPVPKV-SGLERSRE 255

Query: 369 PSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDP 405
            S+    PT S  P  A    P    R  P +  + P
Sbjct: 256 LSAESFLPTASPAPHAAPCPGPPPGSRANPLVKKEPP 292


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 16/183 (8%)

Query: 194 SPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQ 253
           +P     SD E  +    D +D  E     GV +VT          VT T  +     ++
Sbjct: 94  APPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVT---------AVTATAAS---DRME 141

Query: 254 GHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEED---VDTSPGGDYYTSPSSPTSSS 310
                D +  ++GL+R  P+   S SKR +  S + D   V  S   +  +S  S  +S 
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201

Query: 311 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHP 369
           +++T + +  + +P +     +    +PS  DS  +  S      PV    S  + S   
Sbjct: 202 QDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSS 261

Query: 370 SSA 372
           SS+
Sbjct: 262 SSS 264


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 16/183 (8%)

Query: 194 SPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFSLGELQ 253
           +P     SD E  +    D +D  E     GV +VT          VT T  +     ++
Sbjct: 94  APPPVSSSDSEAPEANPADGSDADEDDEDRGVMAVT---------AVTATAAS---DRME 141

Query: 254 GHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEED---VDTSPGGDYYTSPSSPTSSS 310
                D +  ++GL+R  P+   S SKR +  S + D   V  S   +  +S  S  +S 
Sbjct: 142 SDSDSDKSSDNSGLKRKTPALKMSVSKRARKASSDLDQASVSPSEEENSESSSESEKTSD 201

Query: 311 RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDS-PRLSSFTQHHRPVIAVHSGIARSPHP 369
           +++T + +  + +P +     +    +PS  DS  +  S      PV    S  + S   
Sbjct: 202 QDFTPEKKAAVRAPRRGPLGGRKKKKAPSASDSDSKADSDGAKPEPVAMARSASSSSSSS 261

Query: 370 SSA 372
           SS+
Sbjct: 262 SSS 264


>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
          Length = 587

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 48/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)

Query: 190 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVF--SVTELIQVSRTPVVTGTGPNF 247
           + + +P     S    S P + DTT    S  TSG    S T       T      G   
Sbjct: 170 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT 229

Query: 248 SLGELQGHLAYDLNPASTGLRRTLPSTSSSG-----SKRHKSG-----SMEEDVDTSPGG 297
           +L   Q    +  +P ST       ST+SSG     ++ H S      ++     TSPG 
Sbjct: 230 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 289

Query: 298 DYYTSPSSPTSSSRNWTEDMEGGISSPVKK-TEMDKSPFNSPSPQDSPRLSSFTQHHRPV 356
              ++      +S + T       ++PV++ T   +SP ++P+    P  S+ + H    
Sbjct: 290 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH-FPASSTTSGHSEKS 348

Query: 357 IAVHSGIARSPHPSSALHFPTTSILPQTASTY 388
              HS    S    S+ H  T+ +  ++++++
Sbjct: 349 TIFHSSPDASGTTPSSAHSTTSGVSEESSTSH 380



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 45/162 (27%), Positives = 65/162 (40%), Gaps = 18/162 (11%)

Query: 201 SDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSR-----TPVVTGTGPNFSLGELQGH 255
           S    S+P +  TT F +S  TSG+         S+     T   T + P  +   ++  
Sbjct: 376 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVS 435

Query: 256 LAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEE-DVDTSPGGDYYTS-PSSPTSSSRNW 313
             Y   P+ST      P+T  S S      S E   V +SPG    T+ P S T++    
Sbjct: 436 TTYHSRPSST------PTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTA--GL 487

Query: 314 TEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 355
           +E      SSP +  +   SP ++ S   S    S T H RP
Sbjct: 488 SEKSTTFYSSP-RSPDTTLSPASTTSSGVSE--ESTTSHSRP 526


>gi|239752490 PREDICTED: similar to Mucin-12 [Homo sapiens]
          Length = 456

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 48/212 (22%), Positives = 83/212 (39%), Gaps = 14/212 (6%)

Query: 190 EQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVF--SVTELIQVSRTPVVTGTGPNF 247
           + + +P     S    S P + DTT    S  TSG    S T       T      G   
Sbjct: 64  DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT 123

Query: 248 SLGELQGHLAYDLNPASTGLRRTLPSTSSSG-----SKRHKSG-----SMEEDVDTSPGG 297
           +L   Q    +  +P ST       ST+SSG     ++ H S      ++     TSPG 
Sbjct: 124 ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL 183

Query: 298 DYYTSPSSPTSSSRNWTEDMEGGISSPVKK-TEMDKSPFNSPSPQDSPRLSSFTQHHRPV 356
              ++      +S + T       ++PV++ T   +SP ++P+    P  S+ + H    
Sbjct: 184 QGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTH-FPASSTTSGHSEKS 242

Query: 357 IAVHSGIARSPHPSSALHFPTTSILPQTASTY 388
              HS    S    S+ H  T+ +  ++++++
Sbjct: 243 TIFHSSPDASGTTPSSAHSTTSGVSEESSTSH 274



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 52/197 (26%), Positives = 75/197 (38%), Gaps = 23/197 (11%)

Query: 201 SDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSR-----TPVVTGTGPNFSLGELQGH 255
           S    S+P +  TT F +S  TSG+         S+     T   T + P  +   ++  
Sbjct: 270 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDTTPSPPGTTAAPVEVS 329

Query: 256 LAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEE-DVDTSPGGDYYTS-PSSPTSSSRNW 313
             Y   P+ST      P+T  S S      S E   V +SPG    T+ P S T++    
Sbjct: 330 TTYHSRPSST------PTTHFSASSTTLGRSEESTTVHSSPGSTETTALPGSTTTA--GL 381

Query: 314 TEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSAL 373
           +E      SSP +  +   SP ++ S   S    S T H RP          +  P S  
Sbjct: 382 SEKSTTFYSSP-RSPDTTLSPASTTSSGVSE--ESTTSHSRP-----GSTHTTAFPGSTT 433

Query: 374 HFPTTSILPQTASTYFP 390
                SI+P +   Y P
Sbjct: 434 MPGYHSIIPWSRIYYLP 450


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 53/205 (25%), Positives = 72/205 (35%), Gaps = 18/205 (8%)

Query: 234  VSRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDT 293
            V   P  TG     +L  LQ       + +S+    +  S+SSS S    SGS   D   
Sbjct: 2506 VGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD--- 2562

Query: 294  SPGGDYYTSPS-------SPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL 346
            S G      P        SPT + +    +      +P K+     S  +S S   S   
Sbjct: 2563 SEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSS 2622

Query: 347  SSFTQHHRPVIAVHSGIARSPHPSSALH--FPTTSILPQTASTYFPHTAIRYP-PHLNPQ 403
            SS +       +  S  + S   SS+     P    LP+ AS   P    R       P 
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPI 2682

Query: 404  DPLKDLVSLACDPA-----SQQPGP 423
            D L+D  SL+  P      S QP P
Sbjct: 2683 DSLRDSRSLSYSPVERRRPSPQPSP 2707



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 41/148 (27%), Positives = 61/148 (41%), Gaps = 21/148 (14%)

Query: 262  PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 321
            PA +G   T P    S  +R    +    +D +      T PS+P S SR  +E      
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSR---TPPSAP-SQSRMTSE------ 2422

Query: 322  SSPVKKTEMDKSPFNS--PSPQDSPRL---SSFTQHHRPVIAVHSGIARSPHPSSALHFP 376
             +P   + M ++P  S  P  QD PR    S+F+   R +IA  + +A S   SS     
Sbjct: 2423 RAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482

Query: 377  TTSI------LPQTASTYFPHTAIRYPP 398
            TTS       +    +   PH+ +  PP
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPP 2510



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 28/118 (23%), Positives = 45/118 (38%), Gaps = 9/118 (7%)

Query: 235 SRTPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTS 294
           + T  + G  P+ + G      A    P +T  +R  PS+  + +K+  S   ++D D  
Sbjct: 286 THTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR--PSSPETATKQPSSPYEDKDKDKK 343

Query: 295 PGGDYYTSPSSPTSSS-------RNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPR 345
                  SPS   SS+            +  GG   P+  T + + P N PS     R
Sbjct: 344 EKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTR 401



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 32/131 (24%), Positives = 47/131 (35%), Gaps = 25/131 (19%)

Query: 262  PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 321
            PA    R +  S+SSS S    S S      +S      +S SS +SSS +  +     +
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQAL 2659

Query: 322  SSPV---------KKTEMDKSPFNS----------------PSPQDSPRLSSFTQHHRPV 356
              P          +++   + P +S                PSPQ SPR    +   R  
Sbjct: 2660 PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGS 2719

Query: 357  IAVHSGIARSP 367
                 G +RSP
Sbjct: 2720 RRGQRGDSRSP 2730


>gi|148236531 hypothetical protein LOC339779 [Homo sapiens]
          Length = 412

 Score = 36.6 bits (83), Expect = 0.045
 Identities = 43/157 (27%), Positives = 61/157 (38%), Gaps = 19/157 (12%)

Query: 236 RTPVVTGTGPNFSLGELQGHLAYDLNPAST--GLRRTLPSTSSSGSKRHKS--------- 284
           +T V+ G  P +   +L     ++L P S   GL  + P  SS+ S+R  S         
Sbjct: 12  QTSVLPGR-PTWGFSQLVDSSPHNLQPLSPHQGLPPSQPPFSSTQSRRPSSPPPASPSPG 70

Query: 285 ---GSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSP----FNS 337
              GS + + D +P     + PSSPT   +N+        SSP         P    F+ 
Sbjct: 71  FQFGSCDSNSDFAPHPYSPSLPSSPTFFHQNYLSLPRPRASSPSNHWLYPSPPLTPSFSP 130

Query: 338 PSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALH 374
             PQ+S    S  Q       +HS    SP PS   H
Sbjct: 131 SQPQNSSLPHSPCQSPSHPEELHSSTLTSPGPSPPSH 167


>gi|50959191 rho guanine nucleotide exchange factor 5 [Homo sapiens]
          Length = 1597

 Score = 36.2 bits (82), Expect = 0.059
 Identities = 30/122 (24%), Positives = 48/122 (39%), Gaps = 6/122 (4%)

Query: 262  PASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGI 321
            PAS G     P+T+ S      +   + +V         T+   P+S +  WT +++G  
Sbjct: 890  PASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPT 949

Query: 322  S-SPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 380
            S      +E  ++P   P  + +P+  +      PV     G AR P   S LH    S 
Sbjct: 950  SKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPV-----GQARQPEKPSHLHLEKASS 1004

Query: 381  LP 382
             P
Sbjct: 1005 WP 1006


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 35.4 bits (80), Expect = 0.100
 Identities = 48/211 (22%), Positives = 85/211 (40%), Gaps = 15/211 (7%)

Query: 185  RERDAEQSGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTE--LIQVSRTPVVTG 242
            +ER  EQ   P+       E  + ITL TT         G+ S ++     +  TPVV+ 
Sbjct: 1621 QERHLEQRDEPQEPSNKVPEQQRQITLKTTPASGE---RGIASTSDPPTANIKPTPVVS- 1676

Query: 243  TGPNFSLGELQGHLA---YDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDY 299
            T    +   + G+ +     + P  T    T P+T+ + +    +    ++   S G   
Sbjct: 1677 TPSKVTAAAMAGNKSTPRASIRPMVTPATVTNPTTTPTATVMPTTQVESQEAMQSEGPVE 1736

Query: 300  YTSPSSPTSSS-RNWTEDMEGGISSPV--KKTEMDKSPFNSPSPQDSPRLSSFTQH--HR 354
            +      TS S R+ + +++  IS P+   + +   + F  P+ Q  P++    Q     
Sbjct: 1737 HVPVFGSTSGSVRSTSPNVQPSISQPILTVQQQTQATAFVQPTQQSHPQIEPANQELSSN 1796

Query: 355  PVIAVHSGIARSPHPSSALHFPTTSILPQTA 385
             V  V S     P  S+A+ F T S  P ++
Sbjct: 1797 IVEVVQSSPVERPSTSTAV-FGTVSATPSSS 1826


>gi|167736355 mucin 4 isoform a [Homo sapiens]
          Length = 5284

 Score = 35.0 bits (79), Expect = 0.13
 Identities = 57/229 (24%), Positives = 90/229 (39%), Gaps = 33/229 (14%)

Query: 190 EQSGSPRTGMGSDQEDSKP------ITL-DTTDFQESFVTSG--VFSVTELIQVSR---T 237
           +  G+  TG   ++    P       TL +TT +  SF + G   +S TEL   S    T
Sbjct: 455 QSEGAETTGRPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQTELPSTSTGAAT 514

Query: 238 PVVTG---TGPNFSLGELQGHLAYDLNPAS----TGLRRTLPSTSSSGSKRH---KSGSM 287
            +VTG   TG   ++  +   ++    P      +    TLP T+ +G++     ++G+ 
Sbjct: 515 RLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGAQTQWTQETGTT 574

Query: 288 EEDVDTSPGGDYY------TSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQ 341
            E + +SP           TSPSS     R+ ++ +     +    T        S SPQ
Sbjct: 575 GEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQI-----TTAPSTNHSTIHSTSTSPQ 629

Query: 342 DSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFP 390
           +SP +S       P     S   RS  P +     TT     TAS + P
Sbjct: 630 ESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGHSP 678



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 41/152 (26%), Positives = 65/152 (42%), Gaps = 12/152 (7%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSP 295
            TP+   +  + S G+       D + ASTG   +LP T +SS S  H +   + D  ++ 
Sbjct: 2799 TPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSAS 2858

Query: 296  GGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 355
             G     P + TSS+      +    S PV  T    +   +P    SP  S+ T H  P
Sbjct: 2859 TGHATLLPVTDTSSA-----SIGHATSLPVTDTSSISTGHATPLHVTSPS-SASTGHATP 2912

Query: 356  VIAVHSGIARSPHPSSALHFPTTSILPQTAST 387
            +    +  A + H ++ LH  +    P +AST
Sbjct: 2913 LPVTDTSSASTGH-ANPLHVTS----PSSAST 2939



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 45/180 (25%), Positives = 67/180 (37%), Gaps = 31/180 (17%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTS--------- 275
            VT L  VS    TP+   +  + S G     L  D + ASTG    LP TS         
Sbjct: 3043 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDT 3102

Query: 276  --------SSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKK 327
                    SS S  H +     D  ++  GD  + P + TSS+         G ++ +  
Sbjct: 3103 TPLPVTSPSSASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYT-------GDTTSLPV 3155

Query: 328  TEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTAST 387
            T+   S     +P      SS +  H   + V    + S   ++ LH  +    P +AST
Sbjct: 3156 TDTSSSSTGDTTPLLVTETSSVSTGHATPLLVTDASSASTGHATPLHVTS----PSSAST 3211



 Score = 32.7 bits (73), Expect = 0.65
 Identities = 42/161 (26%), Positives = 65/161 (40%), Gaps = 14/161 (8%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSP 295
            TP+      + S G        D + ASTG   +LP T +SS S  H +     D  ++ 
Sbjct: 2143 TPLPVTDTSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSAS 2202

Query: 296  GGDYYTSP-SSPTSSSRNW--------TEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL 346
             G     P +SP+S+S           T     G ++P+  T +  +     +P      
Sbjct: 2203 TGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGDTTPLPVTDA 2262

Query: 347  SSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTAST 387
            SS +  H   + V S  + S   ++ L  P TS  P +AST
Sbjct: 2263 SSVSTGHATSLPVTSLSSVSTGDTTPL--PVTS--PSSAST 2299



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 43/173 (24%), Positives = 66/173 (38%), Gaps = 17/173 (9%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS 284
            VT L  VS    TP+   +  + S G     L  D + ASTG    LP T +S      +
Sbjct: 1171 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHA 1230

Query: 285  GSMEEDVDTSPGGDYYTS-PSSPTSSSRNW---------TEDMEGGISSPVKKTEMDKSP 334
             S+   + ++    + T  P + TSS+            T  +  G ++P+  T    + 
Sbjct: 1231 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1290

Query: 335  FNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTAST 387
                +P      SS +  H   + V S    S      +  P TS  P +AST
Sbjct: 1291 TGHVTPLHVTSPSSASTGHATPLPVTS--LSSASTGDTMPLPVTS--PSSAST 1339



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 43/173 (24%), Positives = 66/173 (38%), Gaps = 17/173 (9%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS 284
            VT L  VS    TP+   +  + S G     L  D + ASTG    LP T +S      +
Sbjct: 1379 VTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTGHATPLPVTDASSVSTDHA 1438

Query: 285  GSMEEDVDTSPGGDYYTS-PSSPTSSSRNW---------TEDMEGGISSPVKKTEMDKSP 334
             S+   + ++    + T  P + TSS+            T  +  G ++P+  T    + 
Sbjct: 1439 TSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSSVSTGDTTPLPVTSTSSAS 1498

Query: 335  FNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTAST 387
                +P      SS +  H   + V S    S      +  P TS  P +AST
Sbjct: 1499 TGHVTPLHVTSPSSASTGHATPLPVTS--LSSASTGDTMPLPVTS--PSSAST 1547



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 43/171 (25%), Positives = 66/171 (38%), Gaps = 11/171 (6%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPST-SSSGSKRHK 283
            VT L  VS    TP+      + S G        D + ASTG    LP T +SS S  H 
Sbjct: 2803 VTSLSSVSTGDTTPLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPDTDTSSASTGHA 2862

Query: 284  SGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDS 343
            +     D  ++  G   + P + TSS       +  G ++P+  T    +     +P   
Sbjct: 2863 TLLPVTDTSSASIGHATSLPVTDTSS-------ISTGHATPLHVTSPSSASTGHATPLPV 2915

Query: 344  PRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAI 394
               SS +  H   + V S  + S   ++ L    TS      +T  P T++
Sbjct: 2916 TDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSSASTGHATPLPVTSL 2966



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 46/186 (24%), Positives = 73/186 (39%), Gaps = 23/186 (12%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPST-SSSGSKRHKSGSMEEDVDTSP 295
            TP+   +  + S G+       D + ASTG   +LP T +SS S  H +     D  ++ 
Sbjct: 1071 TPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSAS 1130

Query: 296  GGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 355
             G   + P + TSS       +  G ++P+  T+   +     +P     LSS +     
Sbjct: 1131 TGHATSLPVTDTSS-------VSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTT 1183

Query: 356  VIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSLACD 415
             + V S       PSSA     T +L          T+     H  P  P+ D  S++ D
Sbjct: 1184 PLPVTS-------PSSASTGHATPLL-------VTDTSSASTGHATPL-PVTDASSVSTD 1228

Query: 416  PASQQP 421
             A+  P
Sbjct: 1229 HATSLP 1234



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 46/190 (24%), Positives = 66/190 (34%), Gaps = 26/190 (13%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS 284
            VT L  VS    TP+      + S G        D +  STG    LP TS+S +     
Sbjct: 4003 VTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSAST--- 4059

Query: 285  GSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSP 344
                        GD    P + TSS+         G ++P+  T+   +     +P    
Sbjct: 4060 ------------GDTTPLPVTDTSSAST-------GHATPLPVTDTSSASTGHATPLPVT 4100

Query: 345  RLSSFTQHHRPVIAVHSGIARSPHPS-SALHFPTTSILPQTASTYFPHTAIRYPPHLNPQ 403
             LSS +  H   +AV S  + S   S S L   T  +   +  T         PP    Q
Sbjct: 4101 SLSSVSTGHATPLAVSSATSASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPPPTTSQ 4160

Query: 404  DPLKDLVSLA 413
              +  + S A
Sbjct: 4161 TIISTIPSTA 4170



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 47/178 (26%), Positives = 67/178 (37%), Gaps = 34/178 (19%)

Query: 208  PITLDTTDFQESFVTSGVFSVTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPAS 264
            P+T DT+       T     VT L  VS    TP+   +  + S G        D + AS
Sbjct: 2946 PVT-DTSSASTGHATP--LPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSAS 3002

Query: 265  TGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSP 324
            TG    LP TS+S +                 GD    P + TSS+         G ++P
Sbjct: 3003 TGQATALPVTSTSSAST---------------GDTTPLPVTDTSSAST-------GQATP 3040

Query: 325  VKKTEMD--KSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSI 380
            +  T +    +   +P P  SP  S+ T H  P++      A S     A   P TS+
Sbjct: 3041 LPVTSLSSVSTGDTTPLPVTSPS-SASTGHATPLLVTD---ASSASTGQATPLPVTSL 3094



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 47/176 (26%), Positives = 65/176 (36%), Gaps = 23/176 (13%)

Query: 195  PRTGMGSDQEDSKPITLDTTDFQESFVTSGV-FSVTELIQVSR---TPVVTGTGPNFSLG 250
            P TG+ S   D     L  TD   +         VT L  VS    TP+   +  + S G
Sbjct: 1682 PVTGLSSATTDDTT-RLPVTDVSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTG 1740

Query: 251  ELQGHLAYDLNPASTGLRRTLPST-SSSGSKRH---------KSGSMEE-------DVDT 293
                 L  D + ASTG    LP T +SS S  H          S S ++       DV +
Sbjct: 1741 HASPLLVTDASSASTGQATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSS 1800

Query: 294  SPGGDYYTSP-SSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSS 348
            +  G     P +SP+S+S   T  +    +S     +    P   PS   S   +S
Sbjct: 1801 ASTGQAIPLPVTSPSSASTGDTTPLPVTDASSASTGDTTSLPVTIPSSASSGHTTS 1856



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 38/159 (23%), Positives = 58/159 (36%), Gaps = 8/159 (5%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTS-SSGSKRHKSGSMEEDVDTSP 295
            TP+      + S G         L+ ASTG    LP TS SS S  H +     D  + P
Sbjct: 1903 TPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVP 1962

Query: 296  GGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 355
             G   + P +  SS       +  G ++P+  T+         +P      SS +     
Sbjct: 1963 TGHATSLPVTDASS-------VSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQAT 2015

Query: 356  VIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAI 394
             + V S  + S   ++ L    TS       T  P T++
Sbjct: 2016 PLPVTSLSSASTGDTTPLPVTDTSSASTGQDTPLPVTSL 2054



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 47/190 (24%), Positives = 70/190 (36%), Gaps = 28/190 (14%)

Query: 208  PITLDTTDFQESFVTSGVFSVTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPAS 264
            P+T D +       TS    VT L  VS    TP+   +  + S G        D + AS
Sbjct: 2258 PVT-DASSVSTGHATS--LPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSAS 2314

Query: 265  TGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSP 324
            TG    LP TS S +            DT+P     TSPSS ++           G ++P
Sbjct: 2315 TGHATPLPVTSLSSASTG---------DTTPLP--VTSPSSAST-----------GHATP 2352

Query: 325  VKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQT 384
            +  T+         +P      SS +  H   + V    + S   ++ L    TS     
Sbjct: 2353 LHVTDASSVSTGDTTPLPVTSSSSASSGHTTPLPVTDASSASTGDTTPLPVTDTSSASTG 2412

Query: 385  ASTYFPHTAI 394
             +T+ P T +
Sbjct: 2413 HATHLPVTGL 2422



 Score = 29.6 bits (65), Expect = 5.5
 Identities = 35/147 (23%), Positives = 57/147 (38%), Gaps = 11/147 (7%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPG 296
            TP+   +  + S G+    L  D +  STG    LP T +S +    +  +    DTS  
Sbjct: 3503 TPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPV-TDTSSA 3561

Query: 297  GDYYTSP---SSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHH 353
                 +P   + P+SSS   T  +    +S V    +      SPS       S+ T H 
Sbjct: 3562 STGQATPLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPS-------SASTGHV 3614

Query: 354  RPVIAVHSGIARSPHPSSALHFPTTSI 380
             P+    +  A + H +  L    +S+
Sbjct: 3615 TPLPVTSTSSASTGHATPLLVTDASSV 3641



 Score = 29.3 bits (64), Expect = 7.2
 Identities = 36/145 (24%), Positives = 54/145 (37%), Gaps = 10/145 (6%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPG 296
            TPV   +  + S G        D + ASTG    LP TS S +    +  +   + +S  
Sbjct: 3311 TPVPVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTGHTTPLHVTIPSSAS 3370

Query: 297  -GDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRP 355
             GD  T P +  SS+         G ++P+  T+         +P     LSS +     
Sbjct: 3371 TGDTSTLPVTGASSAST-------GHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTT 3423

Query: 356  VIAVHSGIARSPHPSSALHFPTTSI 380
             + V    A S     A   P TS+
Sbjct: 3424 PLPVTD--ASSASTGQATPLPVTSL 3446



 Score = 29.3 bits (64), Expect = 7.2
 Identities = 39/168 (23%), Positives = 59/168 (35%), Gaps = 10/168 (5%)

Query: 237  TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTS-SSGSKRHKSGSMEEDVDTSP 295
            TP+   +  + S G+       D +  STG   +LP TS SS S  H +     D  +  
Sbjct: 3807 TPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVS 3866

Query: 296  GGDYYTSPSSPTSSSRNW---------TEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRL 346
             G     P + TSS                   G ++PV  T    +     +P      
Sbjct: 3867 TGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLPVTNA 3926

Query: 347  SSFTQHHRPVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAI 394
            SS +  H   + V S  + S   +S L     S      +T  P T++
Sbjct: 3927 SSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSL 3974



 Score = 28.9 bits (63), Expect = 9.4
 Identities = 34/145 (23%), Positives = 56/145 (38%), Gaps = 10/145 (6%)

Query: 228  VTELIQVSR---TPVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKS 284
            VT L  VS    TP++     + S G        D + ASTG    LP T +S +   ++
Sbjct: 3507 VTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLPVTDTSSASTGQA 3566

Query: 285  GSMEEDVDTSPGGDYYTSPSSPTSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSP 344
              +   + +S     +T+P   TS     T  +  G  +P+  T    +     +P    
Sbjct: 3567 TPLPVTIPSSSSSG-HTTPLPVTS-----TSSVSTGHVTPLHVTSPSSASTGHVTPLPVT 3620

Query: 345  RLSS-FTQHHRPVIAVHSGIARSPH 368
              SS  T H  P++   +    + H
Sbjct: 3621 STSSASTGHATPLLVTDASSVSTGH 3645


>gi|195546902 suppressor of Ty 5 homolog isoform b [Homo sapiens]
          Length = 1083

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 61/226 (26%), Positives = 83/226 (36%), Gaps = 42/226 (18%)

Query: 192 SGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT----GPNF 247
           S +P  G GS      P+    T  Q+   T    S T L   SRTP  +G      PN 
Sbjct: 769 SQTPMYGSGS----RTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNT 824

Query: 248 -SLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP 306
            S  E +   A+D  P         PS  + G   +           +PG   Y  PSSP
Sbjct: 825 PSRAEEEYEYAFDDEPT--------PSPQAYGGTPNPQ---------TPG---YPDPSSP 864

Query: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARS 366
             + + +     G   +P        SP+ +PSPQ S + S   Q +  V    +G   +
Sbjct: 865 QVNPQ-YNPQTPG---TPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNT 920

Query: 367 PHPSSALHFPTTSILPQTAST------YFPHT-AIRYPPHLNPQDP 405
             P+S  + PT S +   AS       Y P T     P   NP  P
Sbjct: 921 HSPAS--YHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTP 964


>gi|195546900 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 61/226 (26%), Positives = 83/226 (36%), Gaps = 42/226 (18%)

Query: 192 SGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT----GPNF 247
           S +P  G GS      P+    T  Q+   T    S T L   SRTP  +G      PN 
Sbjct: 773 SQTPMYGSGS----RTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNT 828

Query: 248 -SLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP 306
            S  E +   A+D  P         PS  + G   +           +PG   Y  PSSP
Sbjct: 829 PSRAEEEYEYAFDDEPT--------PSPQAYGGTPNPQ---------TPG---YPDPSSP 868

Query: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARS 366
             + + +     G   +P        SP+ +PSPQ S + S   Q +  V    +G   +
Sbjct: 869 QVNPQ-YNPQTPG---TPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNT 924

Query: 367 PHPSSALHFPTTSILPQTAST------YFPHT-AIRYPPHLNPQDP 405
             P+S  + PT S +   AS       Y P T     P   NP  P
Sbjct: 925 HSPAS--YHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTP 968


>gi|161169023 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 61/226 (26%), Positives = 83/226 (36%), Gaps = 42/226 (18%)

Query: 192 SGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT----GPNF 247
           S +P  G GS      P+    T  Q+   T    S T L   SRTP  +G      PN 
Sbjct: 773 SQTPMYGSGS----RTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNT 828

Query: 248 -SLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP 306
            S  E +   A+D  P         PS  + G   +           +PG   Y  PSSP
Sbjct: 829 PSRAEEEYEYAFDDEPT--------PSPQAYGGTPNPQ---------TPG---YPDPSSP 868

Query: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARS 366
             + + +     G   +P        SP+ +PSPQ S + S   Q +  V    +G   +
Sbjct: 869 QVNPQ-YNPQTPG---TPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNT 924

Query: 367 PHPSSALHFPTTSILPQTAST------YFPHT-AIRYPPHLNPQDP 405
             P+S  + PT S +   AS       Y P T     P   NP  P
Sbjct: 925 HSPAS--YHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTP 968


>gi|20149524 suppressor of Ty 5 homolog isoform a [Homo sapiens]
          Length = 1087

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 61/226 (26%), Positives = 83/226 (36%), Gaps = 42/226 (18%)

Query: 192 SGSPRTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGT----GPNF 247
           S +P  G GS      P+    T  Q+   T    S T L   SRTP  +G      PN 
Sbjct: 773 SQTPMYGSGS----RTPMYGSQTPLQDGSRTPHYGSQTPLHDGSRTPAQSGAWDPNNPNT 828

Query: 248 -SLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGGDYYTSPSSP 306
            S  E +   A+D  P         PS  + G   +           +PG   Y  PSSP
Sbjct: 829 PSRAEEEYEYAFDDEPT--------PSPQAYGGTPNPQ---------TPG---YPDPSSP 868

Query: 307 TSSSRNWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARS 366
             + + +     G   +P        SP+ +PSPQ S + S   Q +  V    +G   +
Sbjct: 869 QVNPQ-YNPQTPG---TPAMYNTDQFSPYAAPSPQGSYQPSPSPQSYHQVAPSPAGYQNT 924

Query: 367 PHPSSALHFPTTSILPQTAST------YFPHT-AIRYPPHLNPQDP 405
             P+S  + PT S +   AS       Y P T     P   NP  P
Sbjct: 925 HSPAS--YHPTPSPMAYQASPSPSPVGYSPMTPGAPSPGGYNPHTP 968


>gi|26667257 eyes absent 4 isoform d [Homo sapiens]
          Length = 639

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 52/178 (29%), Positives = 73/178 (41%), Gaps = 20/178 (11%)

Query: 259 DLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSP-----GGDYYTSPSSPTS--SSR 311
           DLN  S  +++T   T S  S+   S SME     SP     GGD   S     S  SS 
Sbjct: 6   DLNEQS--VKKTC--TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSST 61

Query: 312 NWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSS 371
           + T +  GG +  V  T       N+PS      L+  T+       ++S    +     
Sbjct: 62  SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTE------PLNSSETTATTGDG 115

Query: 372 ALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSL-ACDPASQQPGPSWYLG 428
           AL   T S++  T+S Y P +A +Y P L P  P   ++S  A    S   G + Y G
Sbjct: 116 ALDTFTGSVI--TSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSG 171


>gi|98991760 eyes absent 4 isoform a [Homo sapiens]
          Length = 639

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 52/178 (29%), Positives = 73/178 (41%), Gaps = 20/178 (11%)

Query: 259 DLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSP-----GGDYYTSPSSPTS--SSR 311
           DLN  S  +++T   T S  S+   S SME     SP     GGD   S     S  SS 
Sbjct: 6   DLNEQS--VKKTC--TESDVSQSQNSRSMEMQDLASPHTLVGGGDTPGSSKLEKSNLSST 61

Query: 312 NWTEDMEGGISSPVKKTEMDKSPFNSPSPQDSPRLSSFTQHHRPVIAVHSGIARSPHPSS 371
           + T +  GG +  V  T       N+PS      L+  T+       ++S    +     
Sbjct: 62  SVTTNGTGGENMTVLNTADWLLSCNTPSSATMSLLAVKTE------PLNSSETTATTGDG 115

Query: 372 ALHFPTTSILPQTASTYFPHTAIRYPPHLNPQDPLKDLVSL-ACDPASQQPGPSWYLG 428
           AL   T S++  T+S Y P +A +Y P L P  P   ++S  A    S   G + Y G
Sbjct: 116 ALDTFTGSVI--TSSGYSPRSAHQYSPQLYPSKPYPHILSTPAAQTMSAYAGQTQYSG 171


>gi|110556636 tankyrase 1-binding protein 1 [Homo sapiens]
          Length = 1729

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 38/132 (28%), Positives = 53/132 (40%), Gaps = 16/132 (12%)

Query: 301 TSPSSPTSSS--RNWTEDMEGGISSPVK-KTEMDKSPFNSPSPQD---SPRLSSFTQHHR 354
           T+P     S+  R W++  EG + SP + + E  K+P     P D   +  L+       
Sbjct: 206 TAPRDEDGSTLFRGWSQ--EGPVKSPAECREEHSKTPEERSLPSDLAFNGDLAKAASSEL 263

Query: 355 PVIAVHSGIARSPHPSSALHFPTTSILPQTASTYFPHTAIRYPPHLNPQD---PLKDLVS 411
           P       I  SP PSS    P +  LP  AS   P +     PHL+P D   P    + 
Sbjct: 264 PADISKPWIPSSPAPSSENGGPASPGLPAEASGSGPGS-----PHLHPPDKSSPCHSQLL 318

Query: 412 LACDPASQQPGP 423
            A  P + Q  P
Sbjct: 319 EAQTPEASQASP 330


>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
           [Homo sapiens]
          Length = 1008

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 33/114 (28%), Positives = 44/114 (38%), Gaps = 4/114 (3%)

Query: 238 PVVTGTGPNFSLGELQGHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDVDTSPGG 297
           PV +GTG   SLG L        +PAS G   T+P+T        K             G
Sbjct: 331 PVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSG 390

Query: 298 DYYTSPSSPTS-SSRNWTEDMEGGISSPVKKTEMDKSPFNSP---SPQDSPRLS 347
              T+ S+ T  +S    + M  G   PV   +MD      P   SP  + R+S
Sbjct: 391 HTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSPGQAERVS 444


>gi|215422375 neural precursor cell expressed, developmentally
           down-regulated 9 isoform 3 [Homo sapiens]
          Length = 834

 Score = 34.3 bits (77), Expect = 0.22
 Identities = 43/164 (26%), Positives = 63/164 (38%), Gaps = 35/164 (21%)

Query: 196 RTGMGSDQEDSKPITLDTTDFQESFVTSGVFSVTELIQVSRTPVVTGTGPNFS--LGELQ 253
           RTG G   E       D  D   S  T GV+ +         P  +  GP FS  +GE++
Sbjct: 159 RTGHGYVYEYPSRYQKDVYDIPPSHTTQGVYDI---------PPSSAKGPVFSVPVGEIK 209

Query: 254 GHLAYDLNPASTGLRRTLPSTSSSGSKRHKSGSMEEDV------------DTSPGGDYYT 301
               YD+ P + G+    PS       R ++G  E+D             D  P G Y  
Sbjct: 210 PQGVYDI-PPTKGVYAIPPSAC-----RDEAGLREKDYDFPPPMRQAGRPDLRPEGVYDI 263

Query: 302 SPSSPTSSSRN----WTEDMEGGISSPVKKTEMDKSPFNSPSPQ 341
            P+    + ++    +  D+ G  + PV +     SP N P PQ
Sbjct: 264 PPTCTKPAGKDLHVKYNCDIPGA-AEPVARRHQSLSP-NHPPPQ 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,525,398
Number of Sequences: 37866
Number of extensions: 1023035
Number of successful extensions: 4625
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 141
Number of HSP's that attempted gapping in prelim test: 4251
Number of HSP's gapped (non-prelim): 385
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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