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Search of human proteins with 45504371
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45504371 family with sequence similarity 9, member B [Homo
sapiens]
(186 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45504371 family with sequence similarity 9, member B [Homo sa... 380 e-106
gi|28274705 family with sequence similarity 9, member A [Homo sa... 197 6e-51
gi|28274703 family with sequence similarity 9, member C [Homo sa... 173 7e-44
gi|24233580 synaptonemal complex protein 3 [Homo sapiens] 77 7e-15
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 50 1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 49 3e-06
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 47 1e-05
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 45 4e-05
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 45 4e-05
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 45 4e-05
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 45 4e-05
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 45 4e-05
gi|148746195 trichohyalin [Homo sapiens] 45 5e-05
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 44 6e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 8e-05
gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo sap... 44 8e-05
gi|34878777 ring finger protein 20 [Homo sapiens] 44 1e-04
gi|71061468 centromere protein E [Homo sapiens] 44 1e-04
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 43 2e-04
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 43 2e-04
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 43 2e-04
gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 42 2e-04
gi|168229156 NFKB activating protein [Homo sapiens] 42 2e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 42 2e-04
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 42 2e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 42 2e-04
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 42 2e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 2e-04
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 42 2e-04
gi|55770834 centromere protein F [Homo sapiens] 42 3e-04
>gi|45504371 family with sequence similarity 9, member B [Homo
sapiens]
Length = 186
Score = 380 bits (975), Expect = e-106
Identities = 186/186 (100%), Positives = 186/186 (100%)
Query: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA
Sbjct: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
Query: 61 EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE 120
EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE
Sbjct: 61 EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE 120
Query: 121 EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE
Sbjct: 121 EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
Query: 181 DSELDN 186
DSELDN
Sbjct: 181 DSELDN 186
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 197 bits (500), Expect = 6e-51
Identities = 125/267 (46%), Positives = 145/267 (54%), Gaps = 82/267 (30%)
Query: 2 AAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAE 61
AA KKH GKDPVRDECEERN FTETREEDVTDEHGEREPFAE DEHTG +T K E A
Sbjct: 66 AAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAA 125
Query: 62 D----LTAKRKRMKMDKTC-SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD- 115
D L AKR+ +K+DK KTKN + AL+KKQLKRQKRDY H+ KLLNVL+EYI +
Sbjct: 126 DIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEK 185
Query: 116 ---------------------------------------------EQKEEEEEEG----- 125
E+KEEEEEEG
Sbjct: 186 QKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG 245
Query: 126 --------------------------EEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLR 159
EEEE I+ FQE+QK+WQQ VR RL+EMK L
Sbjct: 246 GEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLL 305
Query: 160 DQFVKALEDFEDLCDRVFSDEDSELDN 186
+Q +KA +D +D + S E+SELDN
Sbjct: 306 EQLLKAAKDTKDNYCIISSSEESELDN 332
>gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
Length = 166
Score = 173 bits (439), Expect = 7e-44
Identities = 97/148 (65%), Positives = 112/148 (75%), Gaps = 6/148 (4%)
Query: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
MAA + AGKDPV E EER TET+E DVTDEHGER FAETDEHTG +TK+ ED A
Sbjct: 12 MAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTGVDTKELEDIA 71
Query: 61 ED----LTAKRKRM-KMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD 115
D L AKRKR+ K+ K CS+ KN+ K+ LR QLKRQKRDY SLKL NVLEE+ITD
Sbjct: 72 ADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKLPNVLEEFITD 131
Query: 116 EQKEEEEEEGEEEELIRIFQEQQKKWQQ 143
EQK +EE +GE+EE I+IFQEQQK+WQQ
Sbjct: 132 EQK-DEEGDGEKEEQIKIFQEQQKRWQQ 158
>gi|24233580 synaptonemal complex protein 3 [Homo sapiens]
Length = 236
Score = 77.4 bits (189), Expect = 7e-15
Identities = 62/207 (29%), Positives = 101/207 (48%), Gaps = 28/207 (13%)
Query: 1 MAAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA 60
M + GKK++ K ++ R + ED D G E E +K +A
Sbjct: 1 MVSSGKKYSRKSGKPSVEDQFTRAYDFETEDKKDLSGSEEDVIEGKTAVIEKRRKKRSSA 60
Query: 61 ---ED-------------------LTAKRKRMKM-DKTCSKTKN-KSKHALRKKQLKRQK 96
ED L AKRKR++M K KT N K +H + +Q +RQK
Sbjct: 61 GVVEDMGGEVQNMLEGVGVDINKALLAKRKRLEMYTKASLKTSNQKIEHVWKTQQDQRQK 120
Query: 97 RDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
+ +S + L + +++ D QK EE+EE +++ +F++QQK QQ R V+ +RLK +K
Sbjct: 121 LNQEYSQQFLTLFQQWDLDMQKAEEQEE----KILNMFRQQQKILQQSRIVQSQRLKTIK 176
Query: 157 LLRDQFVKALEDFEDLCDRVFSDEDSE 183
L +QF+K++E+ E D + + +E
Sbjct: 177 QLYEQFIKSMEELEKNHDNLLTGAQNE 203
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 50.1 bits (118), Expect = 1e-06
Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 16/167 (9%)
Query: 7 KHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDL--- 63
+H+ +D RD R R + E TD GER+ E D T++ D +
Sbjct: 42 RHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRH 101
Query: 64 ------TAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQ---KRDYIHSLKLLNVLEEYIT 114
K+K +M++ + + K K R++Q R+ +R+ + E
Sbjct: 102 TETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTE 161
Query: 115 DEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
D +E E E E E R + K+ +++ + RER +E RD+
Sbjct: 162 DRHRERERERKRERERKR----ETKERERHTDMERERQRETDRKRDR 204
Score = 33.5 bits (75), Expect = 0.11
Identities = 31/98 (31%), Positives = 47/98 (47%), Gaps = 10/98 (10%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHG--EREPFAETDEHTGANTKKPEDTAEDL 63
+K + VRD ER + E E TD ERE AE + TG +K ED +
Sbjct: 111 QKEREMERVRDR--EREKQKEMGRERQTDRETDRERERQAERERETG-RERKTEDRHRER 167
Query: 64 TAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQ---KRD 98
+RKR + K +TK + +H +++ +R+ KRD
Sbjct: 168 ERERKRERERK--RETKERERHTDMERERQRETDRKRD 203
Score = 27.7 bits (60), Expect = 5.9
Identities = 31/143 (21%), Positives = 54/143 (37%), Gaps = 28/143 (19%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGAN------TKKPEDTAEDLTAKRK 68
RD+ E +R TET E + E E + + T + D + A+R+
Sbjct: 92 RDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERE 151
Query: 69 RMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEE 128
R + ++ +++ + RK++ +R++ E KE E E
Sbjct: 152 RETGRERKTEDRHRERERERKRERERKR-------------------ETKERERHTDMER 192
Query: 129 ELIRIFQEQQKKWQQYRSVRRER 151
E R E +K + R RER
Sbjct: 193 ERQR---ETDRKRDRQRESERER 212
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 48.5 bits (114), Expect = 3e-06
Identities = 41/164 (25%), Positives = 73/164 (44%), Gaps = 13/164 (7%)
Query: 5 GKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAET--DEHTGANTKKPEDTAED 62
GKK + ++ E R E RE++ E G++E E +E ++ ++ E
Sbjct: 51 GKKERESERKKERREREKRKRE-REKERKRERGKKEKKGERKKEERERKKRRREKENKEG 109
Query: 63 LTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
++++ K K +T + K RK++ KR++R K E + +K E +
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERK 169
Query: 123 EEGEEEE----------LIRIFQEQQKKWQQYRSVRRERLKEMK 156
+ GE+EE R +++K ++ R RRER KE K
Sbjct: 170 QVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Score = 43.5 bits (101), Expect = 1e-04
Identities = 38/160 (23%), Positives = 68/160 (42%), Gaps = 18/160 (11%)
Query: 15 RDECEERNRFTETREEDVTDEHGER------------EPFAETDEHTGANTKKPEDTAED 62
+ E ER R ETR+E + ER E E G KK E E+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 63 LTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
K++R + + + K K K +K++ + K K EE E+K+EE
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 123 E------EGEEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
E E ++ E ++ ++++++ ++ R R++R + K
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRK 194
Score = 38.5 bits (88), Expect = 0.003
Identities = 35/168 (20%), Positives = 67/168 (39%), Gaps = 17/168 (10%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
K+ GK + E ++ R + R + ++ GE + + E E +
Sbjct: 78 KRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKE 137
Query: 66 KRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHS--------LKLLNVLEEYITDEQ 117
+RKR + + K + + K RK++ KR+++ K E + +
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERK 197
Query: 118 KEEEEEEGEEEELIRIFQEQQKK---------WQQYRSVRRERLKEMK 156
KE E +E E + R +E++KK W++ +RER + K
Sbjct: 198 KERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 46.6 bits (109), Expect = 1e-05
Identities = 35/138 (25%), Positives = 64/138 (46%), Gaps = 25/138 (18%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
+++ ET E + T+E E+E K+ E E K K+ K +T +
Sbjct: 5 KKKKETEETEETEETEEEEEKE------------GKRKEKRKEKRKEKEKKKKTKETEKR 52
Query: 79 TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQ 138
+ + + RK++ K++K EE +E++EEEEEE EEEE + ++
Sbjct: 53 KEKEEEEKKRKRKRKKKK-------------EEEEREEEEEEEEEEKEEEEKEEGRRRKK 99
Query: 139 KKWQQYRSVRRERLKEMK 156
KK ++ + E+ K+ +
Sbjct: 100 KKKRRRKEEEEEKKKKRR 117
Score = 46.6 bits (109), Expect = 1e-05
Identities = 35/130 (26%), Positives = 62/130 (47%), Gaps = 17/130 (13%)
Query: 35 EHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKR 94
E E E ET+E K+ E E K K+ K +T K K K + ++K+ ++
Sbjct: 9 ETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET-EKRKEKEEEEKKRKRKRK 67
Query: 95 QKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKE 154
+K++ +E++EEEEEE EEE+ +E +++ ++ + R+E +E
Sbjct: 68 KKKE----------------EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEE 111
Query: 155 MKLLRDQFVK 164
K R + K
Sbjct: 112 KKKKRRRKTK 121
Score = 43.5 bits (101), Expect = 1e-04
Identities = 27/129 (20%), Positives = 65/129 (50%), Gaps = 12/129 (9%)
Query: 28 REEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHAL 87
+++ T+E E E E +E G +K ++ ++ K+K + +K K + + K
Sbjct: 5 KKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKR 64
Query: 88 RKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSV 147
++K+ K ++ E +E++EE+EEE +EE R ++++++ ++
Sbjct: 65 KRKKKKEEEE------------REEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEK 112
Query: 148 RRERLKEMK 156
+++R ++ K
Sbjct: 113 KKKRRRKTK 121
Score = 35.0 bits (79), Expect = 0.037
Identities = 29/108 (26%), Positives = 52/108 (48%), Gaps = 8/108 (7%)
Query: 54 KKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYI 113
K+ E+T E + + K K K K K K +KK+ K ++ K E+
Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKR-----KEKEEEEKKR 62
Query: 114 TDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
++K+++EEE EEE +E+++K ++ + R R K+ K R +
Sbjct: 63 KRKRKKKKEEEEREEE---EEEEEEEKEEEEKEEGRRRKKKKKRRRKE 107
Score = 28.5 bits (62), Expect = 3.5
Identities = 23/98 (23%), Positives = 52/98 (53%), Gaps = 13/98 (13%)
Query: 88 RKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSV 147
+KK+ K+++ + E T+E +EEEE+EG+ +E + +++++K ++ +
Sbjct: 1 KKKKKKKKETE-----------ETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKET 49
Query: 148 --RRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSE 183
R+E+ +E K + + K E+ E + +E+ E
Sbjct: 50 EKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKE 87
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 14/155 (9%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA--EDLTAKRKRMKMDKTC 76
E+ R E R + +E +E E ++ E E+ A+RK+ +
Sbjct: 732 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQ----EEA 787
Query: 77 SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQE 136
+ + + + ALR+++ + +++ +L+ L +E++ EEEE ++EEL+R +E
Sbjct: 788 LRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEELLRKQEE 839
Query: 137 QQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+ KW + + RL+E +L ++ L E+
Sbjct: 840 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 874
Score = 35.4 bits (80), Expect = 0.029
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 24/114 (21%)
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQ--LKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
AK +++ ++ ++ + K + RK+Q L+RQ +E I Q+EEE
Sbjct: 726 AKAAKLEQERREAEMRAKREEEERKRQEELRRQ--------------QEEILRRQQEEER 771
Query: 123 EEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRV 176
+ EEEEL R QE+ ++RR+R +E+ L R + + + E+ R+
Sbjct: 772 KRREEEELARRKQEE--------ALRRQREQEIALRRQREEEERQQQEEALRRL 817
Score = 33.1 bits (74), Expect = 0.14
Identities = 34/156 (21%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R + EER R EE++ E + ++ ++ E+ + +R++ +
Sbjct: 765 RQQEEERKR---REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 821
Query: 75 TCSKTKNKSKHALRKKQLKRQK--RDYIHSLKLLNV----LEEYITDEQKEEEEEEGEEE 128
+ + K + LRK++ + K R+ + + L +EE + EEEE + +E
Sbjct: 822 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 881
Query: 129 ELIRIFQEQQKKWQQYRSVRR-------ERLKEMKL 157
E+ R + +++ QQ ++RR ++L +MKL
Sbjct: 882 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 917
Score = 32.7 bits (73), Expect = 0.18
Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 38/162 (23%)
Query: 19 EERNRFTETR---EEDVTDEHGEREPFAETDEHTGA----NTKKPEDTA-----EDLTAK 66
EER R E R EE + + E +A +E N + E+ A E+ K
Sbjct: 818 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 877
Query: 67 RKRMKMD--KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKL------------------- 105
RK +++ K + + + + ALR+ Q ++Q++ + +KL
Sbjct: 878 RKELEVQRQKELMRQRQQQQEALRRLQ-QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 936
Query: 106 -LNVLEEYITDEQKEE---EEEEGEEEELIRIFQEQQKKWQQ 143
L++ E +E++E EE+ ++ EL++ Q+QQ++ QQ
Sbjct: 937 TLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 978
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 14/155 (9%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA--EDLTAKRKRMKMDKTC 76
E+ R E R + +E +E E ++ E E+ A+RK+ +
Sbjct: 759 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQ----EEA 814
Query: 77 SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQE 136
+ + + + ALR+++ + +++ +L+ L +E++ EEEE ++EEL+R +E
Sbjct: 815 LRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEELLRKQEE 866
Query: 137 QQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+ KW + + RL+E +L ++ L E+
Sbjct: 867 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 901
Score = 35.4 bits (80), Expect = 0.029
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 24/114 (21%)
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQ--LKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
AK +++ ++ ++ + K + RK+Q L+RQ +E I Q+EEE
Sbjct: 753 AKAAKLEQERREAEMRAKREEEERKRQEELRRQ--------------QEEILRRQQEEER 798
Query: 123 EEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRV 176
+ EEEEL R QE+ ++RR+R +E+ L R + + + E+ R+
Sbjct: 799 KRREEEELARRKQEE--------ALRRQREQEIALRRQREEEERQQQEEALRRL 844
Score = 33.1 bits (74), Expect = 0.14
Identities = 34/156 (21%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R + EER R EE++ E + ++ ++ E+ + +R++ +
Sbjct: 792 RQQEEERKR---REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 848
Query: 75 TCSKTKNKSKHALRKKQLKRQK--RDYIHSLKLLNV----LEEYITDEQKEEEEEEGEEE 128
+ + K + LRK++ + K R+ + + L +EE + EEEE + +E
Sbjct: 849 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 908
Query: 129 ELIRIFQEQQKKWQQYRSVRR-------ERLKEMKL 157
E+ R + +++ QQ ++RR ++L +MKL
Sbjct: 909 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 944
Score = 32.7 bits (73), Expect = 0.18
Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 38/162 (23%)
Query: 19 EERNRFTETR---EEDVTDEHGEREPFAETDEHTGA----NTKKPEDTA-----EDLTAK 66
EER R E R EE + + E +A +E N + E+ A E+ K
Sbjct: 845 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 904
Query: 67 RKRMKMD--KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKL------------------- 105
RK +++ K + + + + ALR+ Q ++Q++ + +KL
Sbjct: 905 RKELEVQRQKELMRQRQQQQEALRRLQ-QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 963
Query: 106 -LNVLEEYITDEQKEE---EEEEGEEEELIRIFQEQQKKWQQ 143
L++ E +E++E EE+ ++ EL++ Q+QQ++ QQ
Sbjct: 964 TLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 1005
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 14/155 (9%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA--EDLTAKRKRMKMDKTC 76
E+ R E R + +E +E E ++ E E+ A+RK+ +
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQ----EEA 793
Query: 77 SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQE 136
+ + + + ALR+++ + +++ +L+ L +E++ EEEE ++EEL+R +E
Sbjct: 794 LRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEELLRKQEE 845
Query: 137 QQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+ KW + + RL+E +L ++ L E+
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Score = 35.4 bits (80), Expect = 0.029
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 24/114 (21%)
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQ--LKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
AK +++ ++ ++ + K + RK+Q L+RQ +E I Q+EEE
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQ--------------QEEILRRQQEEER 777
Query: 123 EEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRV 176
+ EEEEL R QE+ ++RR+R +E+ L R + + + E+ R+
Sbjct: 778 KRREEEELARRKQEE--------ALRRQREQEIALRRQREEEERQQQEEALRRL 823
Score = 33.1 bits (74), Expect = 0.14
Identities = 34/156 (21%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R + EER R EE++ E + ++ ++ E+ + +R++ +
Sbjct: 771 RQQEEERKR---REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827
Query: 75 TCSKTKNKSKHALRKKQLKRQK--RDYIHSLKLLNV----LEEYITDEQKEEEEEEGEEE 128
+ + K + LRK++ + K R+ + + L +EE + EEEE + +E
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 129 ELIRIFQEQQKKWQQYRSVRR-------ERLKEMKL 157
E+ R + +++ QQ ++RR ++L +MKL
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Score = 32.7 bits (73), Expect = 0.18
Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 38/162 (23%)
Query: 19 EERNRFTETR---EEDVTDEHGEREPFAETDEHTGA----NTKKPEDTA-----EDLTAK 66
EER R E R EE + + E +A +E N + E+ A E+ K
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883
Query: 67 RKRMKMD--KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKL------------------- 105
RK +++ K + + + + ALR+ Q ++Q++ + +KL
Sbjct: 884 RKELEVQRQKELMRQRQQQQEALRRLQ-QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Query: 106 -LNVLEEYITDEQKEE---EEEEGEEEELIRIFQEQQKKWQQ 143
L++ E +E++E EE+ ++ EL++ Q+QQ++ QQ
Sbjct: 943 TLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/155 (22%), Positives = 73/155 (47%), Gaps = 14/155 (9%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTA--EDLTAKRKRMKMDKTC 76
E+ R E R + +E +E E ++ E E+ A+RK+ +
Sbjct: 738 EQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQ----EEA 793
Query: 77 SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQE 136
+ + + + ALR+++ + +++ +L+ L +E++ EEEE ++EEL+R +E
Sbjct: 794 LRRQREQEIALRRQREEEERQQQEEALRRL--------EERRREEEERRKQEELLRKQEE 845
Query: 137 QQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+ KW + + RL+E +L ++ L E+
Sbjct: 846 EAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEE 880
Score = 35.4 bits (80), Expect = 0.029
Identities = 31/114 (27%), Positives = 56/114 (49%), Gaps = 24/114 (21%)
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQ--LKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
AK +++ ++ ++ + K + RK+Q L+RQ +E I Q+EEE
Sbjct: 732 AKAAKLEQERREAEMRAKREEEERKRQEELRRQ--------------QEEILRRQQEEER 777
Query: 123 EEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRV 176
+ EEEEL R QE+ ++RR+R +E+ L R + + + E+ R+
Sbjct: 778 KRREEEELARRKQEE--------ALRRQREQEIALRRQREEEERQQQEEALRRL 823
Score = 33.1 bits (74), Expect = 0.14
Identities = 34/156 (21%), Positives = 71/156 (45%), Gaps = 16/156 (10%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R + EER R EE++ E + ++ ++ E+ + +R++ +
Sbjct: 771 RQQEEERKR---REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERR 827
Query: 75 TCSKTKNKSKHALRKKQLKRQK--RDYIHSLKLLNV----LEEYITDEQKEEEEEEGEEE 128
+ + K + LRK++ + K R+ + + L +EE + EEEE + +E
Sbjct: 828 REEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKEL 887
Query: 129 ELIRIFQEQQKKWQQYRSVRR-------ERLKEMKL 157
E+ R + +++ QQ ++RR ++L +MKL
Sbjct: 888 EVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKL 923
Score = 32.7 bits (73), Expect = 0.18
Identities = 39/162 (24%), Positives = 73/162 (45%), Gaps = 38/162 (23%)
Query: 19 EERNRFTETR---EEDVTDEHGEREPFAETDEHTGA----NTKKPEDTA-----EDLTAK 66
EER R E R EE + + E +A +E N + E+ A E+ K
Sbjct: 824 EERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERK 883
Query: 67 RKRMKMD--KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKL------------------- 105
RK +++ K + + + + ALR+ Q ++Q++ + +KL
Sbjct: 884 RKELEVQRQKELMRQRQQQQEALRRLQ-QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQA 942
Query: 106 -LNVLEEYITDEQKEE---EEEEGEEEELIRIFQEQQKKWQQ 143
L++ E +E++E EE+ ++ EL++ Q+QQ++ QQ
Sbjct: 943 TLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQ 984
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 45.1 bits (105), Expect = 4e-05
Identities = 35/156 (22%), Positives = 70/156 (44%), Gaps = 2/156 (1%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
+K ++ R E ER R E +E D H ER E + T T++ T +
Sbjct: 176 QKEREREKNRQERRERERQRE-KENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 66 KRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEG 125
+RK + + ++ + S+ + + + ++RD E TD +++ E
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 126 EEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
E E R Q ++++ ++ R+ +RER +E + R++
Sbjct: 295 RETERKRERQRERER-ERERNRKRERERERERERER 329
Score = 43.1 bits (100), Expect = 1e-04
Identities = 40/182 (21%), Positives = 77/182 (42%), Gaps = 15/182 (8%)
Query: 12 DPVRDECEERNRFTETREEDVTDEHGEREPFAETD-EHTGANTKKPEDTAEDLTAKRKRM 70
D RD E+ R + E T+ GER +TD + + E E T + ++
Sbjct: 110 DRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR 169
Query: 71 KMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEEL 130
+ ++ K + + K+ +++ +RQ+ N E+ ++ +E E E E E
Sbjct: 170 QTERNRQKEREREKNRQERRERERQREKE-------NKTEDRHSERGRERERERETETET 222
Query: 131 IRIFQEQQKKWQQYRSVR-------RERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSE 183
R Q +++ +Q ++ R RER E + RD+ + D + DR + + +
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQ 282
Query: 184 LD 185
D
Sbjct: 283 TD 284
Score = 37.4 bits (85), Expect = 0.008
Identities = 31/147 (21%), Positives = 58/147 (39%), Gaps = 19/147 (12%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R ER+R +T E ER ET+ ++ D D K + + D+
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIF 134
+ + + RK++ +R++ E +K E E E E E
Sbjct: 286 KRQRRTERDRETERKRERQRER-------------ERERERNRKRERERERERE------ 326
Query: 135 QEQQKKWQQYRSVRRERLKEMKLLRDQ 161
+E+Q++ ++ R RER ++ + D+
Sbjct: 327 RERQRETERDREKERERKRKRQTEMDR 353
Score = 35.8 bits (81), Expect = 0.022
Identities = 38/184 (20%), Positives = 82/184 (44%), Gaps = 13/184 (7%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETD----EHTGANTKKPEDTAE 61
+K ++ R+ R+R T+ + E E+E +TD T N +K + +
Sbjct: 124 QKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREK 183
Query: 62 DLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE 121
+ +R+R + + +KT++ +H+ R ++ +R++ + + E D Q++ E
Sbjct: 184 NRQERRERERQREKENKTED--RHSERGRERERERETETETERKRQTDRE--RDRQRKTE 239
Query: 122 EEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDED 181
E ++ E +E+ + + R RER ++ RD+ K E D + ++ D
Sbjct: 240 REREKQAE-----RERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 182 SELD 185
E +
Sbjct: 295 RETE 298
Score = 35.8 bits (81), Expect = 0.022
Identities = 34/154 (22%), Positives = 70/154 (45%), Gaps = 7/154 (4%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRM-KMD 73
RD ER R + E + + +RE E + + D ++ KRKR +MD
Sbjct: 293 RDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMD 352
Query: 74 KTCSK-TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKE-----EEEEEGEE 127
+ ++ T + + +++ + ++RD + + + D QKE E++ +G+
Sbjct: 353 RERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQR 412
Query: 128 EELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
E + +E+ ++ ++ R RER K+ RD+
Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDR 446
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 44.7 bits (104), Expect = 5e-05
Identities = 34/149 (22%), Positives = 74/149 (49%), Gaps = 13/149 (8%)
Query: 13 PVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKM 72
P +E E+R R RE+++ F E +E + + A+ L + ++
Sbjct: 812 PEEEEKEQRRRQRREREKELQ--------FLEEEEQL-----QRRERAQQLQEEEDGLQE 858
Query: 73 DKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIR 132
D+ +++ + + + QL+ +++ H+L L+E + EQ+ +EEE E + R
Sbjct: 859 DQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREER 918
Query: 133 IFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
+ +Q++ +QYR + + +E +LLR++
Sbjct: 919 EKRRRQEQERQYREEEQLQQEEEQLLREE 947
Score = 42.7 bits (99), Expect = 2e-04
Identities = 33/148 (22%), Positives = 75/148 (50%), Gaps = 10/148 (6%)
Query: 16 DECEERNRFTETR--EEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMD 73
+E E R R T R EE + +E +R+ + +E ++ E +R+R + +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQE-------LRRERQEEE 294
Query: 74 KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRI 133
+ + + + + ++++ +R++++ + +E ++Q E+EE E++L R
Sbjct: 295 QQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRRE 354
Query: 134 FQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
QE++++ QQ R + E +E +L R+Q
Sbjct: 355 -QEEERREQQLRREQEEERREQQLRREQ 381
Score = 42.7 bits (99), Expect = 2e-04
Identities = 41/181 (22%), Positives = 85/181 (46%), Gaps = 19/181 (10%)
Query: 10 GKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKR 69
G+ RD +ER R+ + +E ERE E + ++ + E+ KR+R
Sbjct: 1272 GEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 70 MKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEG--EE 127
+ D+ + + + ++ L+RQ+RD ++ +E + +E+ EE
Sbjct: 1332 QETDRK-FREEEQLLQEREEQPLRRQERD-----------RKFREEELRHQEQGRKFLEE 1379
Query: 128 EELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLC----DRVFSDEDSE 183
E+ +R QE+++K+ + R + +E +L +D+ K E+ + L DR F +E+ +
Sbjct: 1380 EQRLR-RQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQ 1438
Query: 184 L 184
+
Sbjct: 1439 V 1439
Score = 40.4 bits (93), Expect = 9e-04
Identities = 43/166 (25%), Positives = 81/166 (48%), Gaps = 15/166 (9%)
Query: 14 VRDECEERN--RFTETREEDVTDEH--GEREPFAETDEHTGANTKKPEDTAEDLTAKRKR 69
+R E EER R EE+ + E++ E +E K+ E+ + + +R
Sbjct: 507 LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 70 MKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEE-----EE 124
+K ++ + + + R++Q R KR+ L+ EE EQ+E E EE
Sbjct: 567 LKREQEERRDQLLKREEERRQQ--RLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 125 GEEE---ELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALE 167
EEE +L++ ++++++ QQ R ++ER +E +L R++ + LE
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQER-REQRLKREEEEERLE 669
Score = 40.0 bits (92), Expect = 0.001
Identities = 35/173 (20%), Positives = 86/173 (49%), Gaps = 9/173 (5%)
Query: 15 RDECEERNRFTETREEDVTDEHG---EREPFAETDEHTGANTKKPEDTAEDLTAKRKR-M 70
R++ EER RE+ + E E++ E ++ + + +R++ +
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425
Query: 71 KMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE---EEEEGEE 127
+ ++ + + K + R+++LKR++ + LK E + + +K++ ++EE
Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERR 485
Query: 128 EELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
E +++ +E++++ Q+ R + R +E + R+Q +K E+ E L R+ S++
Sbjct: 486 ERWLKLEEEERREQQERREQQLRREQEER--REQRLKRQEEEERLQQRLRSEQ 536
Score = 39.3 bits (90), Expect = 0.002
Identities = 37/161 (22%), Positives = 71/161 (44%), Gaps = 17/161 (10%)
Query: 17 ECEERNRFTETREEDVTDEHGEREPFA----ETDEHTGANTK-------KPEDTAEDLTA 65
E EER E RE+ + E ER E +E + + E+ E L
Sbjct: 492 EEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLK 551
Query: 66 KRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE---- 121
+ + ++++ + + K + R+ QL +++ + +L EE + K EE
Sbjct: 552 REEEKRLEQERREQRLKREQEERRDQLLKREEER-RQQRLKREQEERLEQRLKREEVERL 610
Query: 122 -EEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
+EE E+ L R E++++ Q +S +E ++ +L R+Q
Sbjct: 611 EQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQ 651
Score = 38.1 bits (87), Expect = 0.004
Identities = 32/166 (19%), Positives = 78/166 (46%), Gaps = 18/166 (10%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
EE R E R+ + +E G+R ++ + + ++ +R R + D+ +
Sbjct: 116 EEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWR 175
Query: 79 TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKE------------EEEEEGE 126
+ + ++++ +R + + + S K + EE+ +EQ EE+++
Sbjct: 176 QRQE----WQEREERRAEEEQLQSCKG-HETEEFPDEEQLRRRELLELRRKGREEKQQQR 230
Query: 127 EEELIRIFQEQQKK-WQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
E R+FQE+++K W++ +V R+ ++++ Q + L++ E+
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Score = 38.1 bits (87), Expect = 0.004
Identities = 35/168 (20%), Positives = 82/168 (48%), Gaps = 6/168 (3%)
Query: 17 ECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRK-RMKMDKT 75
E E+ R + + D +E ER E +E ++ + + +R+ R+K +
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 76 CSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQ 135
+ + + + + ++ + ++R+ + + LE+ +++ + E+EE ++ L R
Sbjct: 525 EERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR--- 581
Query: 136 EQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSE 183
E++++ Q+ + + ERL E +L R++ V+ LE E R+ +E E
Sbjct: 582 EEERRQQRLKREQEERL-EQRLKREE-VERLEQEERREQRLKREEPEE 627
Score = 38.1 bits (87), Expect = 0.004
Identities = 28/137 (20%), Positives = 67/137 (48%), Gaps = 3/137 (2%)
Query: 28 REEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHAL 87
+E+ + E E E ++ ++ E L + +++ ++ + + + +
Sbjct: 901 KEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQY 960
Query: 88 RKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKK--WQ-QY 144
RK + +QK + + + + + +EEEE + EEE+L+R +E++++ W+ QY
Sbjct: 961 RKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQY 1020
Query: 145 RSVRRERLKEMKLLRDQ 161
R + +E +LLR++
Sbjct: 1021 RKKDELQQEEEQLLREE 1037
Score = 38.1 bits (87), Expect = 0.004
Identities = 44/202 (21%), Positives = 88/202 (43%), Gaps = 44/202 (21%)
Query: 4 WGKKHAGKDPVRDECEE-----------RNRFTETREEDVTDEHGEREPFAETDEHTGAN 52
W +++ KD ++ E E+ + R + REE+ + E+ E +
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 53 TKKPEDTAEDLTA-----------KRKRMKMDKTC---SKTKNKSKHALRKKQLKRQK-- 96
++ E+L KR+R + ++ C + + + + LR+++ KR++
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 97 --RDYIHSLKLLNVLEEYITDEQ------------KEEEEEEGEEEELIRIFQE--QQKK 140
R Y ++ E+ + +E +EEEE + EEE+L+R QE +Q++
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQER 1195
Query: 141 WQQYRSVRR-ERLKEMKLLRDQ 161
+QYR +R K + RD+
Sbjct: 1196 ERQYREEEELQRQKRKQRYRDE 1217
Score = 38.1 bits (87), Expect = 0.004
Identities = 34/157 (21%), Positives = 73/157 (46%), Gaps = 21/157 (13%)
Query: 20 ERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAK---RKRMKMDKTC 76
E + + REE F E ++ + + ++L ++ RK ++ ++
Sbjct: 1465 EEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Query: 77 SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQE 136
+ + + K ++QL+RQ+R +++++ + + EEE +R +E
Sbjct: 1525 HRQQRQRKFLQEEQQLRRQERG----------------QQRRQDRDRKFREEEQLRQERE 1568
Query: 137 QQKKWQQYRSVRRERLKEMKLLR-DQFVKALEDFEDL 172
+Q+ +Q R R+ RL+E K+ R +Q K +ED + L
Sbjct: 1569 EQQLSRQERD-RKFRLEEQKVRRQEQERKFMEDEQQL 1604
Score = 37.7 bits (86), Expect = 0.006
Identities = 43/183 (23%), Positives = 83/183 (45%), Gaps = 36/183 (19%)
Query: 15 RDECEERNRFTETR-----------EEDVTDEHGEREPFAETDEHTGANTK---KPEDTA 60
R+E E+R R + R EE + E E+ E + + K K E
Sbjct: 915 REEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL 974
Query: 61 EDLTAKRKRMKMDKTC---SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVL---EEYIT 114
+ KR+R + +K + + + + LR+++ KR+++++ + + L EE +
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 115 DEQ-------------KEEEEEEGEEEELI---RIFQEQQKKWQQYRSVRRERLKEMKLL 158
E+ +EEEE + EEE+L+ R + +Q+ +QYR + +E +LL
Sbjct: 1035 REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094
Query: 159 RDQ 161
R++
Sbjct: 1095 REE 1097
Score = 36.6 bits (83), Expect = 0.013
Identities = 31/154 (20%), Positives = 72/154 (46%), Gaps = 7/154 (4%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R E +ER E+ + + E E F + ++ + + +++R + D+
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 75 TCSKTKNKS----KHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKE---EEEEEGEE 127
+ + K + LRK++ K Q+ + +L E+ E++E E +EE ++
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 128 EELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
++ +R Q+ ++K ++ R ++E +E + R+Q
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQ 330
Score = 36.6 bits (83), Expect = 0.013
Identities = 46/180 (25%), Positives = 78/180 (43%), Gaps = 30/180 (16%)
Query: 28 REEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTC---SKTKNKSK 84
REE ERE +E ++ E + KR+R ++++ + + + +
Sbjct: 1095 REEPEKRRRQERERQCREEEEL---QQEEEQLLREEREKRRRQELERQYREEEEVQQEEE 1151
Query: 85 HALRKKQLKRQK----RDYIHSLKLLNVLEEYITDEQK----EEEEEEGEEEELIRIFQE 136
LR++ KR++ R Y +L E+ + +EQ+ E E + EEEEL +
Sbjct: 1152 QLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL-----Q 1206
Query: 137 QQKKWQQYRSV-RRERLK------EMKLLRDQFV----KALEDFEDLCDRVFSDEDSELD 185
+QK+ Q+YR +R LK + +RD V + E F L D D S+ D
Sbjct: 1207 RQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQD 1266
Score = 36.6 bits (83), Expect = 0.013
Identities = 38/172 (22%), Positives = 79/172 (45%), Gaps = 15/172 (8%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
+ER+R E+ V + ER+ F E ++ + E L +R+ ++ +
Sbjct: 1426 QERDRKFREEEQQVRRQERERK-FLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ--- 1481
Query: 79 TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQK--EEEEEEGEEEELIRIFQE 136
+ K ++QL+RQ+RD + L E E+K EEE++ ++ + QE
Sbjct: 1482 -ERDRKFLEEEQQLRRQERDRKFREQELRSQEP----ERKFLEEEQQLHRQQRQRKFLQE 1536
Query: 137 QQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLC----DRVFSDEDSEL 184
+Q+ +Q R +R + ++ K ++ ++ + + L DR F E+ ++
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV 1588
Score = 36.2 bits (82), Expect = 0.017
Identities = 37/163 (22%), Positives = 76/163 (46%), Gaps = 10/163 (6%)
Query: 14 VRDECEERNRFTETREEDVTDEHG-EREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKM 72
+R E + R RE+ + E RE ++ + +K E + KR++ +
Sbjct: 395 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 73 DKTCSKTKNKSKHAL--RKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE-----EEEG 125
+ + +H RK+QLKR + + + L + EE ++Q+ E E+E
Sbjct: 455 RDWLKREEETERHEQERRKQQLKRDQEEERRE-RWLKLEEEERREQQERREQQLRREQEE 513
Query: 126 EEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALED 168
E+ ++ +E+++ Q+ RS ++ R +E + R+Q +K E+
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLR-REQEERREQLLKREEE 555
Score = 35.0 bits (79), Expect = 0.037
Identities = 32/155 (20%), Positives = 78/155 (50%), Gaps = 8/155 (5%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
+ER+R + RE+++ + ER+ F E ++ ++ + E+ +R+ + +
Sbjct: 1497 QERDR--KFREQELRSQEPERK-FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553
Query: 79 TKN-KSKHALRKK----QLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRI 133
+ + + LR++ QL RQ+RD L+ V + + E+E++ +E ++
Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQL 1613
Query: 134 FQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALED 168
QE+ +K+++ + +ER ++ +++ K LE+
Sbjct: 1614 RQERDRKFREDEQLLQEREEQQLHRQERDRKFLEE 1648
Score = 34.7 bits (78), Expect = 0.049
Identities = 34/166 (20%), Positives = 74/166 (44%), Gaps = 22/166 (13%)
Query: 16 DECEERNRFTETREEDVTDEHGEREPFAETDEHTGANT--KKPEDTAEDLTAKRK----- 68
+E E+ E RE+ + E ER + + +E T + ++ + D +R+
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK 490
Query: 69 -----RMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKE---- 119
R + + + + + R+++LKRQ+ + +L + E+ + EQ+E
Sbjct: 491 LEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS--EQQLRREQEERREQ 548
Query: 120 ----EEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
EEE+ E+E + + +Q++ + R E ++ +L R+Q
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ 594
Score = 34.7 bits (78), Expect = 0.049
Identities = 32/177 (18%), Positives = 81/177 (45%), Gaps = 6/177 (3%)
Query: 14 VRDECEERNRFTETREED--VTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMK 71
+R E EER REE+ + E E+ E +E K+ E+ + + + +
Sbjct: 538 LRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEER 597
Query: 72 MDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE---EEEGEEE 128
+++ K + + +++ +R KR+ + +L+ +E+++++ E++ E
Sbjct: 598 LEQRL-KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656
Query: 129 ELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSELD 185
+ ++ +E+++ Q+ + E +E +L ++ +A E + + +SE D
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEAD 713
Score = 34.7 bits (78), Expect = 0.049
Identities = 31/154 (20%), Positives = 72/154 (46%), Gaps = 9/154 (5%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHG---EREPFAETDEHTGANTKKPEDTAED 62
+K ++ +R E EE+ + R+ +E ERE + + ++ E ++
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 63 LTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEE 122
++ R + + + + ++Q RQ+RD + + E++ T E+ EE
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAE-----EQFATQEKSRREE 1861
Query: 123 EEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
+E +EE + QE+++K ++ +RR++ +E +
Sbjct: 1862 QELWQEEEQKRRQERERKLRE-EHIRRQQKEEQR 1894
Score = 33.9 bits (76), Expect = 0.083
Identities = 31/155 (20%), Positives = 73/155 (47%), Gaps = 10/155 (6%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R++ EER RE++ E R E ++ E+ E + ++++ ++
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 75 TCSKTKN-KSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE-EEEGEE---EE 129
+ + + + LR++Q R+++ +L E+ + EQ+EE E++ E+ E+
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLRR--EQQLRREQEEERHEQKHEQERREQ 445
Query: 130 LIRIFQEQQKKW---QQYRSVRRERLKEMKLLRDQ 161
++ QE+++ W ++ + ++ +L RDQ
Sbjct: 446 RLKREQEERRDWLKREEETERHEQERRKQQLKRDQ 480
Score = 33.5 bits (75), Expect = 0.11
Identities = 51/217 (23%), Positives = 91/217 (41%), Gaps = 43/217 (19%)
Query: 6 KKHAGKDPVRDECEERNRFTET----REEDVTDEHGEREPFAETD------------EHT 49
K K +R+E EE+ R ET REE+ + E +P + +
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 50 GANTKKPEDTAEDLTAKRKRMKMDKT--CSKTKNKSKHALRKK------QLKRQKRDYIH 101
G + E +RK +K ++ C + + + + +K QL RQ+RD
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD--- 1429
Query: 102 SLKLLNVLEEYITDEQKEE---EEEEGEEEELIRIFQE-----QQKKWQQYRSVRRER-- 151
+ E+ + +++E EEE+ +E R F+E Q+++ QQ R+R
Sbjct: 1430 --RKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKF 1487
Query: 152 LKEMKLLR----DQFVKALEDFEDLCDRVFSDEDSEL 184
L+E + LR D+ + E +R F +E+ +L
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQL 1524
Score = 33.1 bits (74), Expect = 0.14
Identities = 33/172 (19%), Positives = 79/172 (45%), Gaps = 25/172 (14%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRM---- 70
R+ +++ + +EE + E E+ E ++ + ++ + L +R++
Sbjct: 956 RERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE 1015
Query: 71 ------KMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE---- 120
K D+ + + + K++L+ ++R Y +L E+ + +E++
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 121 ------EEEE--GEEEELIRIFQEQQKKWQQYRSVRRE---RLKEMKLLRDQ 161
+EEE EEE+L+R E++++ ++ R R E + +E +LLR++
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREE 1127
Score = 32.7 bits (73), Expect = 0.18
Identities = 34/165 (20%), Positives = 74/165 (44%), Gaps = 14/165 (8%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
+ER+R E+ + + ER+ E + ++ E L + ++ ++ +
Sbjct: 1687 QERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERY 1746
Query: 79 TKNKSKHALR----KKQLKRQKRD-------YIHSLKLLNVLEEYITDEQKEEEEE---E 124
K + LR ++QL+RQ+RD + + L +D + EEE+ E
Sbjct: 1747 RKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQE 1806
Query: 125 GEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDF 169
EE++L ++ + +W++ + E+ + ++ RD+ +A E F
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF 1851
Score = 32.3 bits (72), Expect = 0.24
Identities = 41/168 (24%), Positives = 72/168 (42%), Gaps = 13/168 (7%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
+K ++ +R E E+ + R + +E R E +K + E L
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE-EQLRQ 1781
Query: 66 KRKRMKMDKTCSKTKNKSKHALRKK----QLKRQKRD--YIHSLKLLNVLEE-----YIT 114
+R+ ++ S K + + LR++ QL+ Q+RD Y + L + E+
Sbjct: 1782 EREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQER 1841
Query: 115 DEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRER-LKEMKLLRDQ 161
D Q EE+ +E+ R QE ++ +Q R RER L+E + R Q
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQ 1889
Score = 32.0 bits (71), Expect = 0.32
Identities = 33/166 (19%), Positives = 72/166 (43%), Gaps = 26/166 (15%)
Query: 14 VRDECEERNRFTET--REEDVTDEHGEREPFAETDEHTGANTK-KPEDTAEDLTAKRKRM 70
+R+E E+R + E REE+ ++ + + D+ + + +PE K +
Sbjct: 1184 LREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPE--------KENAV 1235
Query: 71 KMDKT-CSKTKNKSKHALRKKQLK--------------RQKRDYIHSLKLLNVLEEYITD 115
+ +K C +N+ L QL+ +Q+RD + + + +
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295
Query: 116 EQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
E++ E EE+ E + R QE+++ ++ R +R R + + R++
Sbjct: 1296 EEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Score = 31.6 bits (70), Expect = 0.41
Identities = 30/165 (18%), Positives = 75/165 (45%), Gaps = 17/165 (10%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
EE+ + R++ V E E+E +K E+ ++ +R+R ++
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEW-----RKRETVLRKEEEKLQEEEPQRQRELQEEEEQL 278
Query: 79 TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQ 138
K + + R++Q + Q++ + E+ + +Q+EE E+ EE ++Q+
Sbjct: 279 RKLERQELRRERQEEEQQQQRLRR-------EQQLRRKQEEERREQQEERR-----EQQE 326
Query: 139 KKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSE 183
++ QQ ++ +E + R+Q ++ ++ E ++ +++ E
Sbjct: 327 RREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEE 371
Score = 31.6 bits (70), Expect = 0.41
Identities = 33/165 (20%), Positives = 70/165 (42%), Gaps = 23/165 (13%)
Query: 20 ERNRFTETREEDVTDEHGE--REPFA--------ETDEHTGANTKKPEDTAEDLTAKRKR 69
+R E RE+++ +E E RE + + A K +R+R
Sbjct: 673 KREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732
Query: 70 MKMDKTCSKTKNK-----SKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD--------E 116
+ ++ + +++ + A R++Q + Q+RD+ + E E
Sbjct: 733 QEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLRE 792
Query: 117 QKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
Q+E + E ++ + F ++++ +Q R RRER KE++ L ++
Sbjct: 793 QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEE 837
Score = 31.6 bits (70), Expect = 0.41
Identities = 34/157 (21%), Positives = 74/157 (47%), Gaps = 20/157 (12%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
E+ +F E E+ + + G+++ E D K ED E L +R+ ++ +
Sbjct: 1592 EQERKFMED-EQQLRRQEGQQQLRQERDR------KFRED--EQLLQEREEQQLHRQ--- 1639
Query: 79 TKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQK---EEEEEEGEEEELIRIFQ 135
+ K + QL+RQ+R+ +L + + +E++ E EE++ +E R F+
Sbjct: 1640 -ERDRKFLEEEPQLRRQEREQ----QLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFR 1694
Query: 136 EQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDL 172
E++++ ++ R+ +E +L R + + + E L
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQL 1731
Score = 31.2 bits (69), Expect = 0.54
Identities = 41/185 (22%), Positives = 85/185 (45%), Gaps = 18/185 (9%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAED----LTAK---R 67
R E EE+ R E+ + +E R+ E + E+ +E L+A+ R
Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLR 791
Query: 68 KRMKMDKTCSKTKNKSKHAL----RKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEE 123
++ + + + + + L K+Q +RQ+R+ K L LEE +++E ++
Sbjct: 792 EQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRE---REKELQFLEEEEQLQRRERAQQ 848
Query: 124 EGEEEELIRIFQEQQKKWQQYRSVR-RERLKEMKLLRDQFVKALEDFEDLC---DRVFSD 179
EEE+ ++ QE+++ +Q R + R +L+E + R + A ++ ++ +
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQE 908
Query: 180 EDSEL 184
E+ EL
Sbjct: 909 EEEEL 913
Score = 29.6 bits (65), Expect = 1.6
Identities = 21/83 (25%), Positives = 45/83 (54%), Gaps = 14/83 (16%)
Query: 89 KKQLKRQKRDYIHSLKLLNVLEEYITDEQ---KEEEEEEGEEEELIRIFQEQQKKWQQYR 145
++QL+RQ+RD ++ +EQ ++E E + +EE QE ++K+++
Sbjct: 1681 EQQLRRQERD-----------RKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEE 1729
Query: 146 SVRRERLKEMKLLRDQFVKALED 168
+R+E +E ++++ K LE+
Sbjct: 1730 QLRQETEQEQLRRQERYRKILEE 1752
Score = 28.1 bits (61), Expect = 4.6
Identities = 37/173 (21%), Positives = 77/173 (44%), Gaps = 34/173 (19%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R++ +R + REE+ + GE + + +K + + L + + K
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD-----RKFREEEQQLRRQERERKF-- 1709
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIF 134
+ + LR+++L+R+ R+ EE + Q+ E+E+ +E +I
Sbjct: 1710 ------LQEEQQLRRQELERKFRE-----------EEQL--RQETEQEQLRRQERYRKIL 1750
Query: 135 QEQQ----KKWQQYRSVRRER--LKEMKLLRDQFVKALEDFEDLCDRVFSDED 181
+E+Q ++ QQ R R+R +E +L +++ + L E DR F +E+
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQES--DRKFREEE 1801
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 44.3 bits (103), Expect = 6e-05
Identities = 36/165 (21%), Positives = 67/165 (40%), Gaps = 15/165 (9%)
Query: 7 KHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAK 66
+H +D D +ER R E + + ERE + + K+ D D
Sbjct: 42 RHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRD 101
Query: 67 RKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGE 126
R+R K + ++ +N+ R KQ +R++ + + Q++ E E
Sbjct: 102 RER-KRETDRNRERNRKGGRERDKQTERER--------------DRERERQRQRERERQR 146
Query: 127 EEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+ E R ++++W + ++ER KE K R + K + ED
Sbjct: 147 QRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRRED 191
Score = 41.2 bits (95), Expect = 5e-04
Identities = 30/144 (20%), Positives = 64/144 (44%), Gaps = 8/144 (5%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
+K + RD +R R TE E + +RE +TD + + D
Sbjct: 53 EKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNR 112
Query: 66 KRKR---MKMDKTCSKTKNKSKHALRKKQLKRQ-----KRDYIHSLKLLNVLEEYITDEQ 117
+R R + DK + +++ + R+++ +RQ KR+ + EE + +
Sbjct: 113 ERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172
Query: 118 KEEEEEEGEEEELIRIFQEQQKKW 141
KE ++E E+++ + +++++KW
Sbjct: 173 KERKKERKEKKKEEKRREDKKRKW 196
Score = 32.7 bits (73), Expect = 0.18
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 21/117 (17%)
Query: 38 EREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKR 97
+RE ETD G T++ D + + +R + + + + + R+K+ +RQK
Sbjct: 4 QRERKRETDR--GKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 98 DYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKE 154
D Q++ E E E E R E+Q++ ++ R RER K+
Sbjct: 62 ----------------RDRQRQRERETERETERQR---ERQRQRERKRQTDRERDKD 99
Score = 28.5 bits (62), Expect = 3.5
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 17/109 (15%)
Query: 54 KKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYI 113
++ +T +R+R + + ++T+ +++H R + +R ++
Sbjct: 6 ERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQ---------------- 49
Query: 114 TDEQKEEEEEEGEEEELIRIFQ-EQQKKWQQYRSVRRERLKEMKLLRDQ 161
TD +KE E ++ + + R + E++ + Q+ R +RER ++ RD+
Sbjct: 50 TDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQTDRERDK 98
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 43.9 bits (102), Expect = 8e-05
Identities = 41/149 (27%), Positives = 73/149 (48%), Gaps = 17/149 (11%)
Query: 16 DECEERNRFT-ETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
DE E++ + E EE +E E E E +E +K E+ E+ +++ + K
Sbjct: 2235 DELEKQESLSSEEEEEREEEEEREEEEVREEEEE-----RKEEEEGEEKQVEKEEEEKKK 2289
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEE----EEEGEEEEL 130
K K K K +++K+ ++++ I S E ++DE++EEE EEE + E+
Sbjct: 2290 ---KKKEKKKEEVQEKEEVFEEKEEIMS----EEETESLSDEEEEEESCSLEEEVDREKE 2342
Query: 131 IRIFQEQQKKWQQYRSVRRERLKEMKLLR 159
I ++Q K +Q R R R + + +LR
Sbjct: 2343 ILKKEKQFKLQEQRRKSLRGRERVLSILR 2371
Score = 40.4 bits (93), Expect = 9e-04
Identities = 32/147 (21%), Positives = 69/147 (46%), Gaps = 9/147 (6%)
Query: 16 DECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKT 75
DE E F+E E + + + +E +E ++ E+ + +RK + +
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGE- 2276
Query: 76 CSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQ------KEEEEEEGEEEE 129
K K + +KK+ +++K + ++ EE +++E+ +EEEEE EE
Sbjct: 2277 -EKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEE 2335
Query: 130 LIRIFQEQQKKWQQYRSVRRERLKEMK 156
+ +E KK +Q++ ++ +R K ++
Sbjct: 2336 EVDREKEILKKEKQFK-LQEQRRKSLR 2361
Score = 39.3 bits (90), Expect = 0.002
Identities = 38/165 (23%), Positives = 74/165 (44%), Gaps = 10/165 (6%)
Query: 28 REEDVTDEHGE-----REPFAETDEHTGANTKKPEDTAEDLTAKRKRMKM-DKTCSKTKN 81
+EE +T+E + E + +E G ++ + KRK K DK K +
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSS 2215
Query: 82 KSKHALRKKQLKRQKRDYIHSLKLLNVL---EEYITDEQKEEEEEEGEEEELIRIFQEQQ 138
+ ++ + + L+ L EE +E++E EEEE EEE R +E++
Sbjct: 2216 QVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEER-KEEEE 2274
Query: 139 KKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSE 183
+ +Q E+ K+ K + + V+ E+ + + + S+E++E
Sbjct: 2275 GEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETE 2319
Score = 36.6 bits (83), Expect = 0.013
Identities = 20/76 (26%), Positives = 40/76 (52%)
Query: 110 EEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDF 169
EE + +E++E +EEE EE+ + +E++KK ++ + + KE + + + E+
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318
Query: 170 EDLCDRVFSDEDSELD 185
E L D +E L+
Sbjct: 2319 ESLSDEEEEEESCSLE 2334
Score = 31.6 bits (70), Expect = 0.41
Identities = 31/147 (21%), Positives = 65/147 (44%), Gaps = 17/147 (11%)
Query: 42 FAETDEHTGANTKKPEDTAEDLTAKRKRM--KMDKTCSKTKNKSKHALRKKQLKRQKRDY 99
FA+ +E +K AE L KRK++ K +K + + +K + ++K
Sbjct: 1637 FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVK------ 1690
Query: 100 IHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLR 159
N+L + + + + E+ + +E+EL + +E + ++ E +E L
Sbjct: 1691 -------NILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLV 1743
Query: 160 DQFVKALEDFEDLC--DRVFSDEDSEL 184
++ K E+ E L S+E+++L
Sbjct: 1744 EEKKKLAEEEEALAWQREKLSEEETKL 1770
Score = 29.6 bits (65), Expect = 1.6
Identities = 32/153 (20%), Positives = 69/153 (45%), Gaps = 22/153 (14%)
Query: 35 EHGEREPFAETDE-HTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLK 93
E E+ E ++ H PE E++ + K++K ++ +N +++Q K
Sbjct: 1483 EEWEKRLLQEEEKLHQAGEKLSPE---EEMLQEDKKLKWEEWKQVWENMLSSKSKEQQYK 1539
Query: 94 RQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLK 153
++ LEE ++ E +E+E++ EE+ I +++ KW + + R+R +
Sbjct: 1540 DEEEV---------TLEEEVSREGEEKEQQVTEEQRHI----QEEHKWAR---IHRKRAR 1583
Query: 154 EMKLLRDQFVKALEDFEDLC--DRVFSDEDSEL 184
K + K ++ E L +R + E+ +L
Sbjct: 1584 AEKKRAQEERKLAQEEEKLAQEERQLAQEERKL 1616
Score = 28.9 bits (63), Expect = 2.7
Identities = 34/161 (21%), Positives = 70/161 (43%), Gaps = 29/161 (18%)
Query: 19 EERNRFTETREEDVTDEHG---EREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKT 75
+E+ + + +E+ +E +RE E ++ ++ E+LT + + K
Sbjct: 1779 QEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKN 1838
Query: 76 CSKTKN-----KSKHALRKKQLKRQKRDYIHSLK--------------LLNVLEEYITDE 116
++ K K K A RK+ L K HS K +L +EE +T E
Sbjct: 1839 LAQEKKNLAQEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQE 1898
Query: 117 Q----KEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLK 153
+ K++E+ E++L+++ KK ++ + +E++K
Sbjct: 1899 KETVIKKKEKLAETEKKLVQVEDSLAKKQEK---LAQEKMK 1936
Score = 28.1 bits (61), Expect = 4.6
Identities = 32/140 (22%), Positives = 62/140 (44%), Gaps = 22/140 (15%)
Query: 63 LTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQK--EE 120
L K +R+ ++++ K R + K +K+ KL N + I E+K EE
Sbjct: 2104 LFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEE 2163
Query: 121 E--------------EEEG--EEEELIRIFQEQQKKWQQYRSVRR-ERLKEMKLLRDQFV 163
E EEEG EEEE+I +++W++ + +R ++ KE + V
Sbjct: 2164 ESKLARKHSEVILDDEEEGGIEEEEVIPFL---KRRWRKRKEAKRGDKPKEKFSSQVDEV 2220
Query: 164 KALEDFEDLCDRVFSDEDSE 183
++ E F + + + + + +
Sbjct: 2221 ESEEHFSEEMESLLDELEKQ 2240
>gi|169208122 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 479
Score = 43.9 bits (102), Expect = 8e-05
Identities = 39/159 (24%), Positives = 76/159 (47%), Gaps = 24/159 (15%)
Query: 19 EERNRFTETREEDVTDE-HGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRM--KMDKT 75
EER R E R + + H + E E +E ++ + E L + +R+ + ++
Sbjct: 198 EERLREQEERLHEQEERLHEQEERLCEQEERLCEQEERLREQEERLREQEERLHEQEERL 257
Query: 76 CSKTKN---KSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEE-------- 124
C + + + + +++L Q+R LL +E+ + E+++EE+E
Sbjct: 258 CEQEERLCEQEERLCEQEKLPGQER-------LLEEVEKLLEQERRQEEQERLLERERLL 310
Query: 125 GEEEELI---RIFQEQQKKWQQYRSVRRERLKEMKLLRD 160
E EEL+ R+ Q+ ++ WQQ ERL+E++ LR+
Sbjct: 311 DEVEELLEQERLRQQDERLWQQETLRELERLRELERLRE 349
Score = 34.3 bits (77), Expect = 0.064
Identities = 25/92 (27%), Positives = 51/92 (55%), Gaps = 3/92 (3%)
Query: 87 LRKK--QLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQY 144
LRK+ + RQ + + + ++L++L + +E+EE E+EE + +E+ + ++
Sbjct: 169 LRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEERLCEQEER 228
Query: 145 RSVRRERLKEM-KLLRDQFVKALEDFEDLCDR 175
+ ERL+E + LR+Q + E E LC++
Sbjct: 229 LCEQEERLREQEERLREQEERLHEQEERLCEQ 260
Score = 30.4 bits (67), Expect = 0.92
Identities = 29/142 (20%), Positives = 64/142 (45%), Gaps = 3/142 (2%)
Query: 44 ETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSL 103
+ + T K+ E L A+ + +M ++ + + ++ ++++R +
Sbjct: 161 QLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLHEQEERLHEQEE 220
Query: 104 KLLNVLEEYITDEQKEEEEEE--GEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
+L E E++ E+EE E+EE + +E+ + ++ + ERL E + L Q
Sbjct: 221 RLCEQEERLCEQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQ 280
Query: 162 FVKALEDFEDLCDRVFSDEDSE 183
+ LE+ E L ++ E+ E
Sbjct: 281 -ERLLEEVEKLLEQERRQEEQE 301
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 43.5 bits (101), Expect = 1e-04
Identities = 35/162 (21%), Positives = 80/162 (49%), Gaps = 11/162 (6%)
Query: 25 TETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTC-SKTKNKS 83
+++ ED DE E +P +E + +K ++ A ++ +KR + ++ K + +
Sbjct: 522 SQSSTEDPKDEPAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKERERE 581
Query: 84 KHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQ 143
+ ++K+ +R+K+ S K + ++ E+ + ++ +E E+I+ + + KK Q
Sbjct: 582 REREKEKEREREKQKLKESEKERDSAKD---KEKGKHDDGRKKEAEIIKQLKIELKKAQ- 637
Query: 144 YRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDSELD 185
E KEMKLL D + A ++ D + +++ S+ +
Sbjct: 638 ------ESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAE 673
Score = 33.5 bits (75), Expect = 0.11
Identities = 34/131 (25%), Positives = 61/131 (46%), Gaps = 8/131 (6%)
Query: 51 ANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIH-SLKLLNVL 109
A KK + EDL + K ++ + K + ALRK + ++ +Y+ L +
Sbjct: 665 AAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAKQE 724
Query: 110 EEYITDEQKEEEEE-EGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKAL-E 167
EE + E + E +E+ IR+ Q+ ++K + ER+K +Q K L E
Sbjct: 725 EEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKS-----NQIHKLLKE 779
Query: 168 DFEDLCDRVFS 178
+ E+L D+V +
Sbjct: 780 EKEELADQVLT 790
Score = 32.7 bits (73), Expect = 0.18
Identities = 39/171 (22%), Positives = 69/171 (40%), Gaps = 32/171 (18%)
Query: 19 EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSK 78
E+ N R+E+ ERE E ++ E E K K + ++ +K
Sbjct: 555 EDANEIKSKRDEE------ERERERREKEREREREREKEKEREREKQKLKESEKERDSAK 608
Query: 79 TKNKSKH-------ALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELI 131
K K KH A KQLK + + S K + +L + KE+ ++ +
Sbjct: 609 DKEKGKHDDGRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDK-------V 661
Query: 132 RIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDEDS 182
++ ++K + + R+RLK+ LED E ++ +DED+
Sbjct: 662 QLMAAEKKSKAELEDL-RQRLKD-----------LEDKEKKENKKMADEDA 700
Score = 29.6 bits (65), Expect = 1.6
Identities = 26/112 (23%), Positives = 48/112 (42%), Gaps = 17/112 (15%)
Query: 61 EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQ------------LKRQKRDYIHSLKLLNV 108
E L KRK + +KT+ +S AL + Q LK D
Sbjct: 493 EVLRYKRKLREAQSDLNKTRLRSGSALLQSQSSTEDPKDEPAELKPDSEDLSSQSSASKA 552
Query: 109 LEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRD 160
+E + + + +EEE E E +E++++ ++ R +ER +E + L++
Sbjct: 553 SQEDANEIKSKRDEEERERER-----REKEREREREREKEKEREREKQKLKE 599
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 43.5 bits (101), Expect = 1e-04
Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 3/125 (2%)
Query: 61 EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE 120
E L +++ M++ K K AL +K K Q+ IH + L L ++ ++
Sbjct: 515 EQLRTEKEEMEL-KLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDL 573
Query: 121 EEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
E E + EL+R ++Q KK Q+Y + ++L+ +K+ ++++ED + + +F E
Sbjct: 574 ENELSSKVELLREKEDQIKKLQEY--IDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAE 631
Query: 181 DSELD 185
LD
Sbjct: 632 TVALD 636
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 42.7 bits (99), Expect = 2e-04
Identities = 36/172 (20%), Positives = 79/172 (45%), Gaps = 10/172 (5%)
Query: 7 KHAGKDPVRDEC-EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDL-T 64
+HA K + D C E+ + E +E +E ++ + E + + ++ + T
Sbjct: 364 EHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRT 423
Query: 65 AKRKRMKMDKTCSKTKNK-SKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEE 123
+ K ++ TCS+ +++ + KQL+ +KR Y +K L E ++ Q+E+E
Sbjct: 424 LQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQELSEKLSKLQQEKEAL 483
Query: 124 EGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKL-------LRDQFVKALED 168
E L+++ + + + ++ +L+++K LRD+ + ED
Sbjct: 484 REEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFED 535
Score = 33.5 bits (75), Expect = 0.11
Identities = 36/151 (23%), Positives = 67/151 (44%), Gaps = 32/151 (21%)
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRK-KQLKRQKRDYIHSLKLLNVLEEYITDEQKE---- 119
A++K + K CS + KH +K K+L+ + + S+K N L+E + E+ +
Sbjct: 293 AQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADA 352
Query: 120 EE-----------------------EEEGEEEELIRIFQEQQKKWQQYRSVRRER---LK 153
EE E++ EE++ Q + K QQY+ +++R +
Sbjct: 353 EEKILDLQRKLEHAHKVCLTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQ 412
Query: 154 EMKLLRDQFVKALEDFEDLCDRVFSDEDSEL 184
+ L Q V+ L+D E+L + S + S +
Sbjct: 413 NVDELHRQ-VRTLQDKENLLEMTCSQQQSRI 442
>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
b [Homo sapiens]
Length = 1524
Score = 42.7 bits (99), Expect = 2e-04
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 24/136 (17%)
Query: 42 FAETDEHTGANTKKPEDTAEDLTAKRKRM---------KMDKTCSKTKNKSKHALRKKQL 92
F+ + G K+ + ED A ++ + + DK + + KS A K +L
Sbjct: 269 FSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSL-AFEKAKL 327
Query: 93 KRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQ-KKWQQYRSVRRER 151
KR+K D + + K KE+E++E + EEL +I +E++ KK ++ ++ ER
Sbjct: 328 KREKADALEAKK-------------KEKEDKEKKREELKKIVEEERLKKKEEKERLKVER 374
Query: 152 LKEMKLLRDQFVKALE 167
KE + LR++ K +E
Sbjct: 375 EKEREKLREEKRKYVE 390
>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
a [Homo sapiens]
Length = 1556
Score = 42.7 bits (99), Expect = 2e-04
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 24/136 (17%)
Query: 42 FAETDEHTGANTKKPEDTAEDLTAKRKRM---------KMDKTCSKTKNKSKHALRKKQL 92
F+ + G K+ + ED A ++ + + DK + + KS A K +L
Sbjct: 269 FSPANRRRGRPPKRIHISQEDNVANKQTLASYRSKATKERDKLLKQEEMKSL-AFEKAKL 327
Query: 93 KRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQ-KKWQQYRSVRRER 151
KR+K D + + K KE+E++E + EEL +I +E++ KK ++ ++ ER
Sbjct: 328 KREKADALEAKK-------------KEKEDKEKKREELKKIVEEERLKKKEEKERLKVER 374
Query: 152 LKEMKLLRDQFVKALE 167
KE + LR++ K +E
Sbjct: 375 EKEREKLREEKRKYVE 390
>gi|31317305 M-phase phosphoprotein 10 [Homo sapiens]
Length = 681
Score = 42.4 bits (98), Expect = 2e-04
Identities = 43/169 (25%), Positives = 76/169 (44%), Gaps = 17/169 (10%)
Query: 17 ECEERNRFTETREEDVTDEHGEREPFAETDEHTGANT--KKPEDTAEDLTAKRKRMKMDK 74
E +++ + EE+V+D + E E++ + K P + ED K+++
Sbjct: 123 EADDKEDLEDLEEEEVSDMGNDDPEMGERAENSSKSDLRKSPVFSDEDSDLDFDISKLEQ 182
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEE--GEEEELIR 132
SK +NK + R+K + K L+ +E Y+ + +KEEE ++ EEEE I
Sbjct: 183 Q-SKVQNKGQGKPREKSIVDDK------FFKLSEMEAYLENIEKEEERKDDNDEEEEDID 235
Query: 133 IFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDED 181
F++ + ++LK K R+ ++D D V SDED
Sbjct: 236 FFEDIDSDEDEGGLFGSKKLKSGKSSRNL------KYKDFFDPVESDED 278
Score = 27.3 bits (59), Expect = 7.8
Identities = 33/171 (19%), Positives = 68/171 (39%), Gaps = 26/171 (15%)
Query: 12 DPVRDECEERNRFTETREEDVTDEHGEREPF--------------AETDEHTGANTKKPE 57
D + +E E +ET E+D E+ + + AET++ N KK
Sbjct: 294 DEIAEEEAEELSISETDEDDDLQENEDNKQHKESLKRVTFALPDDAETEDTGVLNVKKNS 353
Query: 58 DTAEDLTAKRKRMKMDKTCSKTKN--KSKHALRKKQLKRQKR----------DYIHSLKL 105
D + KR+ +K S K + K + ++ QKR + H++++
Sbjct: 354 DEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQKRPENSLLEETLHFDHAVRM 413
Query: 106 LNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
V+ E T + ++ ++ ++ + ++++ K Y +R L K
Sbjct: 414 APVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEYKKRLTLDHEK 464
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 42.4 bits (98), Expect = 2e-04
Identities = 32/146 (21%), Positives = 70/146 (47%), Gaps = 6/146 (4%)
Query: 39 REPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRD 98
+ P ++DEHT ++P+ + + + K K S++K +SK +KK KR+ +
Sbjct: 151 KNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKK--KKSSRSKERSKKRRKKKSSKRKHKK 208
Query: 99 YIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLL 158
Y + E +DE + ++ +++E + + + KK+++ RS + +
Sbjct: 209 YSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKK--KHRSKKYKKKRSKKSRKESSDSSS 266
Query: 159 RDQFVKALEDFEDLCDRVFSDEDSEL 184
++ + LE+ DR ++E S+L
Sbjct: 267 KESQEEFLEN--PWKDRTKAEEPSDL 290
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 42.4 bits (98), Expect = 2e-04
Identities = 36/157 (22%), Positives = 70/157 (44%), Gaps = 10/157 (6%)
Query: 5 GKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLT 64
GKK K R+ +ER R + RE+ +R+ E + KK + +
Sbjct: 59 GKKEKKKRKKRERGKERERKRKEREK-------QRKERREKERRKRKKEKKKRERKQRGR 111
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEE 124
+RK+ K K + + + RKK+ K+++R K E +KEE E++
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171
Query: 125 GEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
E R +++++ ++ R ++ER KE + +++
Sbjct: 172 RERNRKER---KKERERKERRERKKERKKERRKKKER 205
Score = 37.4 bits (85), Expect = 0.008
Identities = 33/151 (21%), Positives = 64/151 (42%), Gaps = 8/151 (5%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
K+ GK+ R E + E RE++ E++ KK E +
Sbjct: 68 KRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKEREREN 127
Query: 66 KRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEG 125
K++R + K K + K RK++ + ++R + EE ++ +E +
Sbjct: 128 KQRRER------KRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181
Query: 126 EEEELIRIFQEQQKKWQQYRSVRRERLKEMK 156
E E R +E++K+ ++ R ++ER K+ K
Sbjct: 182 ERERKER--RERKKERKKERRKKKERKKDRK 210
Score = 36.2 bits (82), Expect = 0.017
Identities = 30/140 (21%), Positives = 61/140 (43%), Gaps = 24/140 (17%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
+ E ER + RE++ E G++E +K + ++ KRK + +
Sbjct: 37 KKERREREKRKREREKERKRERGKKEK----------KKRKKRERGKERERKRKEREKQR 86
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIF 134
+ K + K KK+ +R++R + +K++E +E E E R
Sbjct: 87 KERREKERRKRKKEKKKRERKQRGR--------------RERKKKKERKERERENKQRRE 132
Query: 135 QEQQKKWQQYRSVRRERLKE 154
++++K+ ++ R R+R KE
Sbjct: 133 RKRKKRRKKKRRKERKREKE 152
Score = 35.4 bits (80), Expect = 0.029
Identities = 23/111 (20%), Positives = 56/111 (50%)
Query: 51 ANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLE 110
++ KP E K +R + + + K + + +K++ KR+KR+ +
Sbjct: 23 SHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER 82
Query: 111 EYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQ 161
E E++E+E + ++E+ R +++ ++ ++ + R+ER +E K R++
Sbjct: 83 EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRER 133
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 42.4 bits (98), Expect = 2e-04
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 5 GKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLT 64
G++ K E + RNR V+ E E F E+ E+ +E
Sbjct: 1315 GEEKKTKPKEHKEVKGRNR------RKVSSEDSEDSDFQESGVS--------EEVSESED 1360
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEE 124
+R R + K +N+ + +KK+ + + ++ S N EE E++EEEEEE
Sbjct: 1361 EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1420
Query: 125 GEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
EEEE + K + R R+ LK+ K LR + AL++ E+ R+ E
Sbjct: 1421 EEEEE--EDENDDSKSPGKGRKKIRKILKDDK-LRTETQNALKEEEERRKRIAERE 1473
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 42.4 bits (98), Expect = 2e-04
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 17/176 (9%)
Query: 5 GKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLT 64
G++ K E + RNR V+ E E F E+ E+ +E
Sbjct: 1353 GEEKKTKPKEHKEVKGRNR------RKVSSEDSEDSDFQESGVS--------EEVSESED 1398
Query: 65 AKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEE 124
+R R + K +N+ + +KK+ + + ++ S N EE E++EEEEEE
Sbjct: 1399 EQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEE 1458
Query: 125 GEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCDRVFSDE 180
EEEE + K + R R+ LK+ K LR + AL++ E+ R+ E
Sbjct: 1459 EEEEE--EDENDDSKSPGKGRKKIRKILKDDK-LRTETQNALKEEEERRKRIAERE 1511
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 42.4 bits (98), Expect = 2e-04
Identities = 49/193 (25%), Positives = 86/193 (44%), Gaps = 26/193 (13%)
Query: 7 KHAGKDPVRDEC---EERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDL 63
KH K+ + +C +E + T E + + + ++ E D T E+ + L
Sbjct: 635 KHKHKNKEKGQCSISQELKLKSFTYEYEDSKQKSDKAILLENDLST-------ENKLKVL 687
Query: 64 TAKRKRMKMDKTCSKTKNKSKHALRK-----KQLKRQKRDYIHSLKLLNVLEEYITDEQK 118
R K ++ SK K + K L K K++K +D S + EE +
Sbjct: 688 KHDRDHFKKEEKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFR-----EEKDRSNKA 742
Query: 119 EEE---EEEGEEEELIRIFQEQQKKWQQYRSVRRER---LKEMKLLRDQFVKALEDFEDL 172
E+E +E+ +EE +R+++E++KK + R + E+ LKE K+ +++ ED E L
Sbjct: 743 EKERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKL 802
Query: 173 CDRVFSDEDSELD 185
EDS D
Sbjct: 803 KKEKVYREDSAFD 815
Score = 33.1 bits (74), Expect = 0.14
Identities = 43/172 (25%), Positives = 81/172 (47%), Gaps = 30/172 (17%)
Query: 28 REEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA-----KRKRMKMDKTCS---KT 79
+EE ++ E + + DE + K+ +DT +D++ K + K +K S K+
Sbjct: 696 KEEKLSKMKLEEKEWLFKDEKS---LKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKS 752
Query: 80 KNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQK 139
+ K L K++ K++ +D L+ N L+E ++KE +IF+E ++
Sbjct: 753 PKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKE------------KIFKEDKE 800
Query: 140 KWQQYRSVRRERLKEMKLLRDQFVKALED-----FEDLCDRVFSD-EDSELD 185
K ++ + R + + ++QF++ ED +D DR FSD DS D
Sbjct: 801 KLKKEKVYREDSAFDEYCNKNQFLEN-EDTKFSLSDDQRDRWFSDLSDSSFD 851
Score = 33.1 bits (74), Expect = 0.14
Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 13/132 (9%)
Query: 6 KKHAGKDPVRDECEERNRFTETRE--EDVTDEHGEREPFAETDEHTGANTKKPEDTAEDL 63
++ K+P RD ++R R+ E V ++H E++ T+++ + D+ +D
Sbjct: 1174 ERQKDKEP-RDRRKDRGAADAGRDKKEKVFEKHKEKKDKESTEKYKDRKDRASVDSTQDK 1232
Query: 64 T--------AKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD 115
A++K DK +K+K+K K + ++ R LL LEE
Sbjct: 1233 KNKQKLPEKAEKKHAAEDK--AKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALH 1290
Query: 116 EQKEEEEEEGEE 127
E +E+ ++ E
Sbjct: 1291 EYREDSNDKISE 1302
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.4 bits (98), Expect = 2e-04
Identities = 45/176 (25%), Positives = 76/176 (43%), Gaps = 29/176 (16%)
Query: 11 KDPVRDECEERNRFTETREEDVTDEHG--------EREPFAETDEHTGANTKKPEDTAED 62
KD + + +R ET + VT + G P A D++ G KK +
Sbjct: 264 KDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKK---- 319
Query: 63 LTAKRKRMKMDKTCSKTKNKSKHALR---------KKQLKRQKRDYIHSLKLLNVL---- 109
K+K K +K K K SK ++ K++ +RQKR+ +K L L
Sbjct: 320 ---KKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKR 376
Query: 110 -EEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVK 164
EE +++K E +++ E+E R+ +E + + R R +KLL+ Q V+
Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVE 432
Score = 41.2 bits (95), Expect = 5e-04
Identities = 42/164 (25%), Positives = 81/164 (49%), Gaps = 18/164 (10%)
Query: 15 RDECEERNRFTETREEDVT---DEHGEREPFAETDEHTGANT--------KKPEDTAEDL 63
RDE + + R + +EE T D+ ++E + +E T + E+ AE
Sbjct: 243 RDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETP 302
Query: 64 TAKRKRMKMDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEE 123
TA + DK K K+K K K++ +++K+ S + ++E + ++EEE +
Sbjct: 303 TAAEDDNEGDK---KKKDKKKKKGEKEEKEKEKKKG-PSKATVKAMQEALAKLKEEEERQ 358
Query: 124 EGEEEELIRIFQE---QQKKWQQYRSVRRERLKEMKLLRDQFVK 164
+ EEEE I+ +E ++K+ ++ +RER K+ + R + +K
Sbjct: 359 KREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLK 402
Score = 28.1 bits (61), Expect = 4.6
Identities = 27/103 (26%), Positives = 42/103 (40%), Gaps = 18/103 (17%)
Query: 26 ETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKSKH 85
E E+ V ++ E P E +E EDT + + M D+ K + H
Sbjct: 474 EVMEQGVPEKE-ETPPPVEPEEE--------EDTEDAGLDDWEAMASDEETEKVEGNKVH 524
Query: 86 ALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEE 128
K+ + ++ + EE +E +EEEEEEGE E
Sbjct: 525 IEVKENPEEEEEEEE---------EEEEDEESEEEEEEEGESE 558
Score = 28.1 bits (61), Expect = 4.6
Identities = 12/20 (60%), Positives = 16/20 (80%)
Query: 110 EEYITDEQKEEEEEEGEEEE 129
EE +E++EEE+EE EEEE
Sbjct: 532 EEEEEEEEEEEEDEESEEEE 551
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 42.4 bits (98), Expect = 2e-04
Identities = 38/166 (22%), Positives = 74/166 (44%), Gaps = 20/166 (12%)
Query: 7 KHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAK 66
+H G++ DE E R E R + V D ER + + ++ + D
Sbjct: 646 RHQGRN---DELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERD---- 698
Query: 67 RKRMKMDKTCSKTKNKSKHALRKKQLKRQK-RDYIHSLKLLNVLEEYITDEQKEEEEEEG 125
R+R K ++ + + + + R+K+ R++ RD H + ++E E +
Sbjct: 699 REREK-ERELERERAREREREREKERDRERDRDRDHD-----------RERERERERDRE 746
Query: 126 EEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFED 171
+E E R +E++++ ++ R RER +E RD+ + D+ED
Sbjct: 747 KEREREREERERERERERERERERERERERARERDKERERQRDWED 792
Score = 32.7 bits (73), Expect = 0.18
Identities = 30/145 (20%), Positives = 59/145 (40%), Gaps = 16/145 (11%)
Query: 15 RDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDK 74
R+ ER R E E + ERE E + ++ + D R R D
Sbjct: 677 RERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDR---DH 733
Query: 75 TCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIF 134
+ + + + ++++ +R++R+ E E++ E E E E
Sbjct: 734 DRERERERERDREKEREREREERER----------ERERERERERERERERERARERDKE 783
Query: 135 QEQQKKWQ---QYRSVRRERLKEMK 156
+E+Q+ W+ + R RRE+ +E++
Sbjct: 784 RERQRDWEDKDKGRDDRREKREEIR 808
Score = 30.4 bits (67), Expect = 0.92
Identities = 31/139 (22%), Positives = 59/139 (42%), Gaps = 14/139 (10%)
Query: 34 DEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMDKTCSKTKNKS-----KHALR 88
D R + E D + + + D A D + +R+ + D+ ++ +++ +H R
Sbjct: 594 DSWETRSSYPERDRYPERDNR---DQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGR 650
Query: 89 KKQLKRQKR------DYIHSLKLLNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQ 142
+L+R +R D + + E E+ E E E E E +E++ + +
Sbjct: 651 NDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERE 710
Query: 143 QYRSVRRERLKEMKLLRDQ 161
+ R RER KE RD+
Sbjct: 711 RAREREREREKERDRERDR 729
Score = 27.7 bits (60), Expect = 5.9
Identities = 32/153 (20%), Positives = 63/153 (41%), Gaps = 20/153 (13%)
Query: 48 HTGANTKKPEDTAEDLTAKRKRMKMDK-------TCSKTKNKSKHALRKKQLKRQKRDYI 100
H+G+ ++ + E ++ R+ K T S ++ H+ R+ + ++ +
Sbjct: 1229 HSGSRDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHS 1288
Query: 101 HSLKL-----LNVLEEYITDEQKEEEEEEGEEEELIRIFQEQQKKWQQYRSVRRERLKEM 155
S L + Y D ++E E + + E R + K W + R R+RL+E
Sbjct: 1289 RSGSFDSRDRLQERDRYEHDRERERERRDTRQREWDR---DADKDWPRNRD--RDRLRER 1343
Query: 156 KLLRDQFVKALEDFED---LCDRVFSDEDSELD 185
+ R++ + D E + D V D D + D
Sbjct: 1344 ERERERDKRRDLDRERERLISDSVERDRDRDRD 1376
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 42.0 bits (97), Expect = 3e-04
Identities = 36/168 (21%), Positives = 81/168 (48%), Gaps = 13/168 (7%)
Query: 16 DECEERNRFTETREEDVTDEHGEREPFAETDEH--TGANTKKPEDTAEDLTAKRKR--MK 71
+E + +N ET D+ ++ ++E ++ A+ +K D ++DL KR+ +
Sbjct: 524 EEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHIEQ 583
Query: 72 MDKTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLL-----NVLEEYITDEQKEEEEEEGE 126
++ SKT+ +SK L +LK+++ + + K L + E+ +T + E+E + +
Sbjct: 584 LNDKLSKTEKESKALLSALELKKKEYEELKEEKTLFSCWKSENEKLLTQMESEKENLQSK 643
Query: 127 EEELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALEDFEDLCD 174
L + QQ K +Y ER++ +++ R+ + + ++ D
Sbjct: 644 INHLETCLKTQQIKSHEY----NERVRTLEMDRENLSVEIRNLHNVLD 687
Score = 30.8 bits (68), Expect = 0.70
Identities = 34/176 (19%), Positives = 75/176 (42%), Gaps = 17/176 (9%)
Query: 6 KKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTA 65
K A + ++ E E + T +E+++ GE+ A + K +D ++LT
Sbjct: 2613 KMTAKETELQREMHEMAQKTAELQEELS---GEKNRLAGELQLLLEEIKSSKDQLKELTL 2669
Query: 66 KRKRMKMDKTCS-----KTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKEE 120
+ +K C + + K + + + QL+ + + H LL+ ++Y + Q
Sbjct: 2670 ENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYEVEIQTYR 2729
Query: 121 EEEEGEEE---------ELIRIFQEQQKKWQQYRSVRRERLKEMKLLRDQFVKALE 167
E+ +EE +L++ +E+ + + E LK+ K+ ++V L+
Sbjct: 2730 EKLTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLK 2785
Score = 28.5 bits (62), Expect = 3.5
Identities = 37/167 (22%), Positives = 69/167 (41%), Gaps = 25/167 (14%)
Query: 14 VRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAEDLTAKRKRMKMD 73
++ E EE E + E +R ++ E T A+ +T L K K +++
Sbjct: 859 IKGEIEENLMKAEQMHQSFVAETSQR--ISKLQEDTSAHQNVVAETLSALENKEKELQLL 916
Query: 74 KTCSKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITDEQKE------------EE 121
+T+ ++LK+ SLK L +L E ++ E+KE EE
Sbjct: 917 NDKVETEQAEI-----QELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEE 971
Query: 122 --EEEGEEEELIRIFQEQQ----KKWQQYRSVRRERLKEMKLLRDQF 162
+E G +E+ +++ +K + + + ER K + L DQ+
Sbjct: 972 LTQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQY 1018
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.128 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,615,562
Number of Sequences: 37866
Number of extensions: 392437
Number of successful extensions: 11982
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 393
Number of HSP's successfully gapped in prelim test: 610
Number of HSP's that attempted gapping in prelim test: 5321
Number of HSP's gapped (non-prelim): 3933
length of query: 186
length of database: 18,247,518
effective HSP length: 96
effective length of query: 90
effective length of database: 14,612,382
effective search space: 1315114380
effective search space used: 1315114380
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.