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Search of human proteins with 45446749
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45446749 kinesin family member 5A [Homo sapiens]
(1032 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45446749 kinesin family member 5A [Homo sapiens] 2021 0.0
gi|4758650 kinesin family member 5C [Homo sapiens] 1418 0.0
gi|4758648 kinesin family member 5B [Homo sapiens] 1332 0.0
gi|46852174 kinesin family member 3A [Homo sapiens] 301 2e-81
gi|4758646 kinesin family member 3B [Homo sapiens] 296 5e-80
gi|30794488 kinesin family member 27 [Homo sapiens] 282 1e-75
gi|71061468 centromere protein E [Homo sapiens] 281 3e-75
gi|116686122 kinesin family member 4 [Homo sapiens] 280 7e-75
gi|150010604 kinesin family member 4B [Homo sapiens] 277 4e-74
gi|83716024 kinesin family member 21B [Homo sapiens] 270 5e-72
gi|13699824 kinesin family member 11 [Homo sapiens] 270 7e-72
gi|9910266 kinesin family member 15 [Homo sapiens] 268 2e-71
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 265 2e-70
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 265 2e-70
gi|38569484 kinesin family member 21A [Homo sapiens] 259 7e-69
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 257 3e-68
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 246 6e-65
gi|41352705 kinesin family member 3C [Homo sapiens] 244 4e-64
gi|203096856 kinesin family member 7 [Homo sapiens] 239 7e-63
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 238 3e-62
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 237 4e-62
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 237 4e-62
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 237 4e-62
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 237 4e-62
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 234 2e-61
gi|157502184 kinesin family member 6 [Homo sapiens] 224 4e-58
gi|40254834 kinesin family member 1C [Homo sapiens] 223 6e-58
gi|46852172 kinesin family member 13B [Homo sapiens] 221 3e-57
gi|148612831 kinesin family member 18A [Homo sapiens] 218 2e-56
gi|156616271 kinesin family member 19 [Homo sapiens] 218 3e-56
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 2021 bits (5235), Expect = 0.0
Identities = 1032/1032 (100%), Positives = 1032/1032 (100%)
Query: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQE 60
MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQE
Sbjct: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQE 60
Query: 61 QVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHI 120
QVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHI
Sbjct: 61 QVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHI 120
Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEI 180
YSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEI
Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEI 180
Query: 181 LDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVS 240
LDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVS
Sbjct: 181 LDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVS 240
Query: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTM 300
KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTM
Sbjct: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTM 300
Query: 301 FICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETI 360
FICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETI
Sbjct: 301 FICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETI 360
Query: 361 AKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEE 420
AKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEE
Sbjct: 361 AKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEE 420
Query: 421 IRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAA 480
IRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAA
Sbjct: 421 IRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAA 480
Query: 481 KDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVS 540
KDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVS
Sbjct: 481 KDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVS 540
Query: 541 GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKS 600
GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKS
Sbjct: 541 GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKS 600
Query: 601 VVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEES 660
VVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEES
Sbjct: 601 VVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEES 660
Query: 661 YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDE 720
YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDE
Sbjct: 661 YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDE 720
Query: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL
Sbjct: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
Query: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL
Sbjct: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
Query: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI
Sbjct: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
Query: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPECISYTNSLFQNYQNLYLQ 960
KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPECISYTNSLFQNYQNLYLQ
Sbjct: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPECISYTNSLFQNYQNLYLQ 960
Query: 961 ATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQA 1020
ATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQA
Sbjct: 961 ATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQA 1020
Query: 1021 KLFPLHQETAAS 1032
KLFPLHQETAAS
Sbjct: 1021 KLFPLHQETAAS 1032
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 1418 bits (3670), Expect = 0.0
Identities = 716/939 (76%), Positives = 826/939 (87%), Gaps = 7/939 (0%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYHA 65
ECSIKV+CRFRPLN+AEILRGDKFIP F+GD++VVIG GKPYVFDRV PPNTTQEQVY+A
Sbjct: 6 ECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQEQVYNA 65
Query: 66 CAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDE 125
CA QIVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA DIF+HIYSMDE
Sbjct: 66 CAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHIYSMDE 125
Query: 126 NLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVID 185
NLEFHIKVSYFEIYLDKIRDLLDV+KTNL+VHEDKNRVP+VKGCTERFVSSPEE++DVID
Sbjct: 126 NLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEVMDVID 185
Query: 186 EGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAE 245
EGK+NRHVAVTNMNEHSSRSHSIFLINIKQEN+ETE+KLSGKLYLVDLAGSEKVSKTGAE
Sbjct: 186 EGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVSKTGAE 245
Query: 246 GAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCS 305
GAVLDEAKNINKSLSALGNVISALAEGTK++VPYRDSKMTRILQDSLGGNCRTT+ ICCS
Sbjct: 246 GAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCS 305
Query: 306 PSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEA 365
PS +N+AETKSTLMFGQRAKTIKNT SVNLELTAE+WKKKYEKEKEK K K I LE
Sbjct: 306 PSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVIQHLEM 365
Query: 366 ELSRWRNGENVPETERLAGEEAALGAELCEETPVNDN-SSIVVRIAPEERQKYEEEIRRL 424
EL+RWRNGE VPE E+++ ++ E C+ TP+ DN + +V I+ EE++KY+EEI L
Sbjct: 366 ELNRWRNGEAVPEDEQISAKDQK-NLEPCDNTPIIDNIAPVVAGISTEEKEKYDEEISSL 424
Query: 425 YKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEV 484
Y+QLDDKDDEINQQSQL EKLKQQMLDQ+ELL STR D EK+Q EL+ LQ EN+AAKDEV
Sbjct: 425 YRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEV 484
Query: 485 KEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQR 544
KEVLQALEELAVNYDQKSQEVE+K++ N+ L DEL+QK T+ + + EL +LQE+S HQ+
Sbjct: 485 KEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQRELSQLQELSNHQK 544
Query: 545 KRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKR 604
KR E+LN L+KDL E I+G ++K +++G IEEEFT+ARLYISK+KSEVKS+V R
Sbjct: 545 KRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISKMKSEVKSLVNR 604
Query: 605 CRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSL 664
+QLE+ Q++ +RKM + REL++CQLLISQHEAKI+SLT+YMQ++E K+R LEES DSL
Sbjct: 605 SKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQKRRQLEESQDSL 664
Query: 665 SDELAKLQAQETVHEVALKDKEPD----TQDADEVKKALELQMESHREAHHRQLARLRDE 720
S+ELAKL+AQE +HEV+ +DKE + QDA+E+KKALE QMESHREAH +QL+RLRDE
Sbjct: 665 SEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREAHQKQLSRLRDE 724
Query: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
I EKQK IDE++DLNQKLQLE EKL +DY KLK E+ E+ KL++L L ++ EQ+++DL
Sbjct: 725 IEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDL 784
Query: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
KGLEETV+RELQTLHNLRKLFVQD+TTRVKKS E++ +D GG +QKQKISFLENNLEQL
Sbjct: 785 KGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQL 844
Query: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE ALKEAKE AM+D++RYQQEVDRI
Sbjct: 845 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRI 904
Query: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTR 939
KEAVR K+ +R HSAQIAKP+RPGHYPASSPT + R
Sbjct: 905 KEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIR 943
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 1332 bits (3446), Expect = 0.0
Identities = 677/939 (72%), Positives = 806/939 (85%), Gaps = 9/939 (0%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQEQVYHAC 66
EC+IKV+CRFRPLN++E+ RGDK+I FQG+D+VVI KPY FDRVF +T+QEQVY+ C
Sbjct: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDC 65
Query: 67 AMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDEN 126
A +IVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI +DIFN+IYSMDEN
Sbjct: 66 AKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDEN 125
Query: 127 LEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDE 186
LEFHIKVSYFEIYLDKIRDLLDV+KTNLSVHEDKNRVP+VKGCTERFV SP+E++D IDE
Sbjct: 126 LEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDE 185
Query: 187 GKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEG 246
GKSNRHVAVTNMNEHSSRSHSIFLIN+KQEN +TEQKLSGKLYLVDLAGSEKVSKTGAEG
Sbjct: 186 GKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEG 245
Query: 247 AVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSP 306
AVLDEAKNINKSLSALGNVISALAEG+ +YVPYRDSKMTRILQDSLGGNCRTT+ ICCSP
Sbjct: 246 AVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSP 304
Query: 307 SSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAE 366
SSYN++ETKSTL+FGQRAKTIKNT VN+ELTAEQWKKKYEKEKEK K + TI LE E
Sbjct: 305 SSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENE 364
Query: 367 LSRWRNGENVPETERLAGEEAALGAELCEE--TPVNDNSS----IVVRIAPEERQKYEEE 420
L+RWRNGE VP E+ E+A L A ++ T ND + ++ ER+K EEE
Sbjct: 365 LNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEE 424
Query: 421 IRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAA 480
I +LYKQLDDKD+EINQQSQL+EKLK QMLDQEELL STR D + +Q EL+ LQ+ENDA+
Sbjct: 425 IAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDAS 484
Query: 481 KDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVS 540
K+EVKEVLQALEELAVNYDQKSQEVE+K+++ +LL DEL+QK AT+ S+++ELQ+L+E++
Sbjct: 485 KEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMT 544
Query: 541 GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKS 600
HQ+KR AE++ L+KDL+E + VGN ++K P E +G I+EEFTVARLYISK+KSEVK+
Sbjct: 545 NHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQP-EGTGMIDEEFTVARLYISKMKSEVKT 603
Query: 601 VVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEES 660
+VKRC+QLE+ Q E ++KME +EL++CQL ISQHEAKI+SLTEY+Q+VE KKR LEES
Sbjct: 604 MVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEES 663
Query: 661 YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDE 720
D+LS+EL +L+AQE VHE+ K+ Q A+EVK+A+E Q++SHRE H +Q++ LRDE
Sbjct: 664 VDALSEELVQLRAQEKVHEME-KEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDE 722
Query: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
+ K K I +L+D NQK+ LE E+L+ ++EKLK+ + EKS KL ELT + +R EQ++QDL
Sbjct: 723 VEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDL 782
Query: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
KGLEETVA+ELQTLHNLRKLFVQD+ TRVKKSAE++ +D+GG +QKQKISFLENNLEQL
Sbjct: 783 KGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQL 842
Query: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE ALKEAKE A +D++RYQQEVDRI
Sbjct: 843 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRI 902
Query: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTR 939
KEAVR K+ +RGHSAQIAKP+RPG +PA+SPT+P R
Sbjct: 903 KEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIR 941
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 301 bits (772), Expect = 2e-81
Identities = 205/570 (35%), Positives = 311/570 (54%), Gaps = 38/570 (6%)
Query: 9 SIKVLCRFRPLNQAEI------------LRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPN 56
++KV+ R RPLN+ E +RG I + + D S K + FD VF P
Sbjct: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGT--ITVHKTDSSNE-PPKTFTFDTVFGPE 70
Query: 57 TTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDI 116
+ Q VY+ A I+ VL GYNGTIFAYGQT +GKT TMEG P+L GIIP I
Sbjct: 71 SKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHI 130
Query: 117 FNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTN-LSVHEDKNRVPFVKGCTERFVS 175
F HI + + F ++VSY EIY +++RDLL +T L V E + ++K + V+
Sbjct: 131 FGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVN 190
Query: 176 SPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLS---GKLYLVD 232
+ +++ ++ G NR V TNMNEHSSRSH+IF I I+ + + GKL+LVD
Sbjct: 191 NADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVD 250
Query: 233 LAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSL 292
LAGSE+ +KTGA G L EA IN SLS LGNVISAL +G ++VPYR+SK+TR+LQDSL
Sbjct: 251 LAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSL 310
Query: 293 GGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEK 352
GGN +T M P+ YN ET STL + RAK IKN A +N E + ++++KE E+
Sbjct: 311 GGNSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARIN-EDPKDALLRQFQKEIEE 369
Query: 353 TKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPE 412
K + E ++ +G ++ +E EE +G + + + E
Sbjct: 370 LKKKLEEGEEI--------SGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSPDKMIE 421
Query: 413 ERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSH 472
+ K +EE + L +LD +++E N+ +EK ++ +L ++ +++ + +LS
Sbjct: 422 MQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQ-------EHQSLLEKLSA 474
Query: 473 LQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESE 532
L+ + ++L EE ++ + E+EE+ ++ + L EL +K L +E +
Sbjct: 475 LEKKVIVGG---VDLLAKAEEQEKLLEESNMELEERRKRAEQLRRELEEKEQERLDIEEK 531
Query: 533 LQRLQEVSGHQRKRIAEVLNGLMKDLSEFS 562
LQE + + K++ +V LM SE +
Sbjct: 532 YTSLQEEAQGKTKKLKKVWTMLMAAKSEMA 561
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/332 (21%), Positives = 138/332 (41%), Gaps = 39/332 (11%)
Query: 550 VLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLE 609
+L K++ E + GE +ISG+ E++ + K + + K+
Sbjct: 359 LLRQFQKEIEELKKKLEEGEEISGSDISGSEEDDDEEGEVGEDGEKRKKRRGKKKVSP-- 416
Query: 610 NLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELA 669
+ +E K++ + L + + + K R+ E + LK ++ + SL ++L+
Sbjct: 417 DKMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKA---QQEHQSLLEKLS 473
Query: 670 KLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTID 729
L+ + V V L K A+E +K LE + E ++ +LR E+ EK++
Sbjct: 474 ALEKKVIVGGVDLLAK------AEEQEKLLE-ESNMELEERRKRAEQLRRELEEKEQ--- 523
Query: 730 ELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAR 789
E D+ +K E+ Q +KLK E+ L + H+ ++++GL E + R
Sbjct: 524 ERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKSEMADLQQEHQ---REIEGLLENI-R 579
Query: 790 ELQTLHNLRKLFVQDVTTR----VKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKV-- 843
+L L+ L + + R + ++ ED G Q + +++ NN+ + T V
Sbjct: 580 QLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIG--EWQLKCVAYTGNNMRKQTPVPD 637
Query: 844 ------------HKQLVRDNADLRCELPKLEK 863
H L LR L KLE+
Sbjct: 638 KKEKDPFEVDLSHVYLAYTEESLRQSLMKLER 669
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 296 bits (759), Expect = 5e-80
Identities = 212/598 (35%), Positives = 319/598 (53%), Gaps = 40/598 (6%)
Query: 1 MAETNNECSIKVLCRFRPLNQAEILRG-DKFIPIFQGDDSVVIGG---------KPYVFD 50
M++ + S++V+ R RP+N E DK + + V + K + FD
Sbjct: 1 MSKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFD 60
Query: 51 RVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIP 110
V+ N Q ++Y +V VL G+NGTIFAYGQT +GKT+TMEG DP+ G+IP
Sbjct: 61 AVYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIP 120
Query: 111 RIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTN-LSVHEDKNRVPFVKGC 169
IF HI S +N ++ ++ SY EIY ++IRDLL +T L + E + +VK
Sbjct: 121 NSFDHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDL 179
Query: 170 TERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIK--QENMETEQKLS-G 226
+ S +EI V++ G NR V TNMNEHSSRSH+IF+I I+ + ++ E + G
Sbjct: 180 SSFVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVG 239
Query: 227 KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTR 286
KL LVDLAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G +++PYRDSK+TR
Sbjct: 240 KLNLVDLAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTR 299
Query: 287 ILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKY 346
+LQDSLGGN +T M P+SYN ET +TL + RAK IKN VN E + +++
Sbjct: 300 LLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREF 358
Query: 347 EKEKEKTKAQ--KETIAKLEAELSRWRNGEN--VPETERLAGEEAALGAELCEE--TPVN 400
++E + KAQ K +I + + R G + E E GEE + ++
Sbjct: 359 QEEIARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418
Query: 401 DNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQE-ELLVST 459
+ I R E+ EE RL K+ + K +++ ++ E L ++ E +LLV
Sbjct: 419 EKLEIEKRAIVEDHSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGG 478
Query: 460 RG---DNEKVQRELSHLQSENDAAKDEVKEVLQALE-------ELAVNYDQKSQEVEEKS 509
+ + Q+ L + E K +E+ Q +E EL Y QEV+ K+
Sbjct: 479 KNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKT 538
Query: 510 QQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGN 567
++ + L +L ++++E+ LQE +R+ + + N L ++L +I+ N
Sbjct: 539 KKLKKLFSKLQ-------AVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHLIIEN 589
Score = 53.9 bits (128), Expect = 8e-07
Identities = 76/340 (22%), Positives = 138/340 (40%), Gaps = 68/340 (20%)
Query: 645 EYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALEL--- 701
E + +E++KR + E + +++E +L LK+KE +D K A E+
Sbjct: 416 EQQEKLEIEKRAIVEDHSLVAEEKMRL----------LKEKEKKMEDLRREKDAAEMLGA 465
Query: 702 ---QMES-----------HREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQA 747
MES H + L + R EI E+++ E++ + E +L+
Sbjct: 466 KIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKE 525
Query: 748 DYEKLKSEEHEKSTKLQ-----------ELTFLYERHEQSKQDLKGLEETVARELQTLHN 796
Y L+ E K+ KL+ E+ L E H + +Q+L+ + + REL+ H
Sbjct: 526 TYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
Query: 797 LRKLFVQ-DVTTRVKKSAEMEPEDSGGIHSQKQKISFLENN---------------LEQL 840
+ + F+ + +++ A + E+ H + I+ LEN L Q
Sbjct: 586 IIENFIPLEEKSKIMNRAFFDEEED---HWKLHPITRLENQQMMKRPVSAVGYKRPLSQH 642
Query: 841 TKVHKQLVRDNADLRCE---LPKLEKRLRATAE-RVKALEGALKEAKEGAMKDKRRYQQE 896
++ ++R A R E L +L+ R T + A+ ++ A + A++D+ Q +
Sbjct: 643 ARM-SMMIRPEARYRAENIVLLELDMPSRTTRDYEGPAIAPKVQAALDAALQDEDEIQVD 701
Query: 897 VDRI------KEAVRYKSSGKRGHSAQIAKPVRPGHYPAS 930
K R KS K G S+ + YP S
Sbjct: 702 ASSFESTANKKSKARPKSGRKSGSSSSSSGTPASQLYPQS 741
Score = 33.5 bits (75), Expect = 1.1
Identities = 31/192 (16%), Positives = 90/192 (46%), Gaps = 6/192 (3%)
Query: 719 DEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQ 778
+E E ++ +E D + + + EKL+ + ++ E+H S +E L + E+ +
Sbjct: 395 EEEEEGEEGEEEGDDKDDYWREQQEKLEIE-KRAIVEDH--SLVAEEKMRLLKEKEKKME 451
Query: 779 DL---KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLEN 835
DL K E + +++ + + + +++ + ++ + I QK++ ++
Sbjct: 452 DLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQ 511
Query: 836 NLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQ 895
+E + +L + L+ E+ K+L+ +++A++ + + +E +K+++ +Q
Sbjct: 512 QMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQ 571
Query: 896 EVDRIKEAVRYK 907
+ + ++ K
Sbjct: 572 TQNELTRELKLK 583
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 282 bits (722), Expect = 1e-75
Identities = 254/939 (27%), Positives = 454/939 (48%), Gaps = 100/939 (10%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKF-IPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
E +KV R RPL E L + + + V+IG + + FD VF N+TQ++VY+
Sbjct: 3 EIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEVYN 62
Query: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM----GIIPRIARDIFNHI 120
C +V ++ GYN T+FAYGQT SGKT+T+ G H ++ GIIPR ++IF I
Sbjct: 63 TCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGG-HIASVVEGQKGIIPRAIQEIFQSI 121
Query: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVTKT--NLSVHEDKNRVPFVKGCTERFVSSPE 178
S +++F++KVSY E+Y + +RDLL++ + +L + ED+ + G E V S
Sbjct: 122 -SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESAG 180
Query: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQ--ENMETEQKLS--------GKL 228
E++ +++ G + RH T MNEHSSRSH+IF I+I Q +NME + S K
Sbjct: 181 EVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSKF 240
Query: 229 YLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--SYVPYRDSKMTR 286
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + + S++PYRD+K+TR
Sbjct: 241 HFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKITR 300
Query: 287 ILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKY 346
+L+DSLGG+ +T M C SPSS N E+ ++L + RA+ I+N +VN ++ +
Sbjct: 301 LLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESD----RI 356
Query: 347 EKEKEKTKAQKETIAKLEAELSRWR--NGENVPETERLAGEEAALGAELCEETPVNDNSS 404
++ + + K +E + +A +S+ N E P+T R+ E E+
Sbjct: 357 DEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRIHSLE--------EQVAQLQGEC 408
Query: 405 IVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNE 464
+ + EE + +++ + + + ++ + +I+++++ +L + T E
Sbjct: 409 LGYQCCVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRKAVLTSFRGIGGTASLEE 468
Query: 465 KVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVA 524
Q ++ LQ K E+K+ L V ++QK EV+E Q Q++V E
Sbjct: 469 GPQ-HVTVLQ-----LKRELKKCQCVLAADEVVFNQKELEVKELKNQVQMMVQENKGHAV 522
Query: 525 TMLSLESELQRLQEVSGHQRKRIAE---VLNGLMKDLSEFSVIVGNGEIKLPVEISGAIE 581
+ L+ Q+V+ Q ++I E +++ L ++L++ ++ V + + +
Sbjct: 523 S-------LKEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSVTSSAKE---NCGDGPD 572
Query: 582 EEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSS----CQLLISQHE 637
R Y + + + + ++ +V M R + Q+L+ E
Sbjct: 573 ARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRSQMLLGHIE 632
Query: 638 AKIRSL-TEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHE-VALKDKEPDTQDADEV 695
+ + L ++ + + ++ +E + + +Q ++V V L D + +TQ +D
Sbjct: 633 EQDKVLHCQFSDNSDDEESEGQEKSGTRCRSRSWIQKPDSVCSLVELSDTQDETQKSDLE 692
Query: 696 KKALELQMESHREAHHRQLARLR------------------------DEINEKQKTIDEL 731
+ +L+++ +E+ L +L+ D I E KT ++
Sbjct: 693 NE--DLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDLIKELIKTGNDA 750
Query: 732 KDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAREL 791
K ++++ L++ KL+ D E+ K E E +LQEL E + S +K + R+
Sbjct: 751 KSVSKQYSLKVTKLEHDAEQAKVELIETQKQLQEL----ENKDLSDVAMKVKLQKEFRKK 806
Query: 792 QTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDN 851
LR +Q KK A + ++ + +Q + ++ QL ++ +R+
Sbjct: 807 MDAAKLRVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQL----QRKLREE 862
Query: 852 ADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDK 890
+ R +L + KR ++ K E LK +E +K K
Sbjct: 863 NEKRKQLDAVIKR-----DQQKIKEIQLKTGQEEGLKPK 896
Score = 61.6 bits (148), Expect = 4e-09
Identities = 109/551 (19%), Positives = 225/551 (40%), Gaps = 75/551 (13%)
Query: 408 RIAPEERQKY----------EEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLV 457
RI E +QK E+ I+ L K +D Q S + KL+ + L+
Sbjct: 717 RILTEAKQKMRELTINIKMKEDLIKELIKTGNDAKSVSKQYSLKVTKLEHDAEQAKVELI 776
Query: 458 STRGDNEKVQ-RELSH------LQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQ 510
T+ ++++ ++LS LQ E D K +Q L++ Q S+++ S
Sbjct: 777 ETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKK----QQDSKKLASLSI 832
Query: 511 QNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEI 570
QN+ +EL Q V M + +LQR +RK++ V+ + + E + G E
Sbjct: 833 QNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEG 892
Query: 571 KLP----------VEISGAIEEEFTVARLYISK--IKSEVKSVVKRCRQLENLQVECHRK 618
P G+ + +L K + EV+ V+ + ++LE L+ + ++
Sbjct: 893 LKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKR 952
Query: 619 MEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLE----ESYDSLSDELAKLQAQ 674
+ ++S+ EA ++ +K HLE S +L+ + K+ +
Sbjct: 953 -----------EAIVSKKEALLQ-----------EKSHLENKKLRSSQALNTDSLKISTR 990
Query: 675 ETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDL 734
+ E L +K Q + +K + + QL + R ++EK K L
Sbjct: 991 LNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPE 1050
Query: 735 NQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTL 794
+ + +LE+ E L++ ++ +Q R + + L A L+ L
Sbjct: 1051 EEHVLFQLEE---GIEALEAAIEYRNESIQ------NRQKSLRASFHNLSRGEANVLEKL 1101
Query: 795 HNLRKLFVQDVTTRV--KKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNA 852
L + ++ + R K E E +++++ K+ LE + + ++ L D+
Sbjct: 1102 ACLSPVEIRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERD-NMVRELESAL--DHL 1158
Query: 853 DLRCELPKLEKRLRATAERVKALEGALKEAK-EGAMKDKRRYQQEVDRIKEAVRYKSSGK 911
L+C+ +L + + ++++ L KE EG M+ + Y+ ++ ++++ + +
Sbjct: 1159 KLQCD-RRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKDLYFYKKTS 1217
Query: 912 RGHSAQIAKPV 922
R H ++ + V
Sbjct: 1218 RDHKKKLKELV 1228
Score = 58.9 bits (141), Expect = 2e-08
Identities = 111/491 (22%), Positives = 213/491 (43%), Gaps = 72/491 (14%)
Query: 418 EEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSEN 477
EE+ + L+ Q D D+ + Q EK + + + + D+ ELS Q E
Sbjct: 632 EEQDKVLHCQFSDNSDDEESEGQ--EKSGTRCRSRSWI---QKPDSVCSLVELSDTQDET 686
Query: 478 DAAKDEVKEVLQALEELAVNYDQKSQEVE-EKSQQNQLLVDELSQKVATM---LSLESEL 533
K +++ E+L ++ Q+SQE+ +K + ++ ++ E QK+ + + ++ +L
Sbjct: 687 Q--KSDLEN-----EDLKIDCLQESQELNLQKLKNSERILTEAKQKMRELTINIKMKEDL 739
Query: 534 QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISK 593
+ +G+ K +++ ++S+ V E IE + + L +K
Sbjct: 740 IKELIKTGNDAKSVSK----------QYSLKVTKLEHDAEQAKVELIETQKQLQELE-NK 788
Query: 594 IKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELK 653
S+V VK LQ E +KM+ + Q Q K+ SL S++ +
Sbjct: 789 DLSDVAMKVK-------LQKEFRKKMDAAKLRVQVLQKK-QQDSKKLASL-----SIQNE 835
Query: 654 KR--HLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHH 711
KR LE+S D + + K+Q Q + E K K+ D + +K E+Q+++ +E
Sbjct: 836 KRANELEQSVDHMKYQ--KIQLQRKLREENEKRKQLDAVIKRDQQKIKEIQLKTGQEEGL 893
Query: 712 RQLARLRDEINEKQK-----TIDELKDLNQKLQL-------------ELEKLQADYEKLK 753
+ A D N K++ +ID L+ L+++ + ELE+L+AD +K +
Sbjct: 894 KPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKRE 953
Query: 754 SEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSA 813
+ +K LQE + L + +S Q L T + ++ T NL + + + +++ S
Sbjct: 954 AIVSKKEALLQEKSHLENKKLRSSQAL----NTDSLKISTRLNLLEQELSEKNVQLQTST 1009
Query: 814 EMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVK 873
E +++ L+ +QL K + + R P+ E L E ++
Sbjct: 1010 AEEKT------KISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEGIE 1063
Query: 874 ALEGALKEAKE 884
ALE A++ E
Sbjct: 1064 ALEAAIEYRNE 1074
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 281 bits (718), Expect = 3e-75
Identities = 273/968 (28%), Positives = 457/968 (47%), Gaps = 107/968 (11%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVI---GGKPYVFDRVFPPNTTQEQVY 63
E ++ V R RPLN E G+ ++ D++V+ G K + FDRVF N T + VY
Sbjct: 4 EGAVAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVY 63
Query: 64 HACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSM 123
A I+ + GYNGTIFAYGQT+SGKT+TM G +G+IPR DIF I
Sbjct: 64 EEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMG---SEDHLGVIPRAIHDIFQKIKKF 120
Query: 124 DENLEFHIKVSYFEIYLDKIRDLLDVTK--TNLSVHEDKNRVPFVKGCTERFVSSPEEIL 181
+ EF ++VSY EIY + I DLL T+ L + ED NR +V TE V + E L
Sbjct: 121 PDR-EFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMAL 179
Query: 182 DVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQ------ENMETEQKLSGKLYLVDLAG 235
I +G+ +RH T MN+ SSRSH+IF + ++ N E K+S L LVDLAG
Sbjct: 180 KWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVS-HLNLVDLAG 238
Query: 236 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-TKSYVPYRDSKMTRILQDSLGG 294
SE+ ++TGA G L E NIN+SL LG VI L++G ++ YRDSK+TRILQ+SLGG
Sbjct: 239 SERAAQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGG 298
Query: 295 NCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKE----- 349
N +T + +P S++ ET + L F AK +KNT VN T E K+Y KE
Sbjct: 299 NAKTRIICTITPVSFD--ETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLK 356
Query: 350 ------KEKTKAQ---KETIAKL--EAELSRWRNGENVPETERLAGEEAALGAE------ 392
+T+AQ K+ +A+L E +L + E + R+ ++L +
Sbjct: 357 KQLEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAK 416
Query: 393 -------------LCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQS 439
+ + D +I I + + +R + + + + D +
Sbjct: 417 RKRRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTL 476
Query: 440 QLIEKLK----QQMLDQEEL---LVSTRGDNEKVQRELSHLQSENDAAKDEVKE-----V 487
+ +++ ++L+QE + L S R D + + + L++E + + ++KE
Sbjct: 477 DTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDE 536
Query: 488 LQALEELAVNYDQKSQEVEEKSQ----------QNQLLVDELSQKVATMLSLESELQRLQ 537
+ALE DQ+ Q + E S NQ L +ELS KV + E ++++LQ
Sbjct: 537 FEALER-KTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQ 595
Query: 538 EVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSE 597
E Q+ L + DLS +S+ I+ P ++ + + TVA + ++
Sbjct: 596 EYIDSQK------LENIKMDLS-YSL----ESIEDPKQMKQTLFDAETVA------LDAK 638
Query: 598 VKSVVKRCRQLENLQVECHRKMEVTGREL-SSCQLLISQHEAKIRSLTEYMQSVELKKRH 656
+S R LE E +++ T +++ + QL SQ EAK + + + ++
Sbjct: 639 RESAFLRSENLE--LKEKMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNE 696
Query: 657 LEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKAL--ELQMESHREAHHRQL 714
+ + + ++ K E + D + + E +AL E+ + S ++ ++
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV 756
Query: 715 ARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHE 774
RLR EI +K + + + KL E+ ++ + L E + L Y+ +
Sbjct: 757 ERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTD 816
Query: 775 QSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLE 834
Q Q+ K L ++ + + + Q++ V S E + DS + + K ++S+
Sbjct: 817 QEFQNFKTLHMDFEQKYKMVLEENERMNQEI---VNLSKEAQKFDS-SLGALKTELSYKT 872
Query: 835 NNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQ 894
L++ T+ ++ + + L+ +L + L+ T ER K L + E + +++ +
Sbjct: 873 QELQEKTREVQERLNEMEQLKEQLENRDSTLQ-TVEREKTL---ITEKLQQTLEEVKTLT 928
Query: 895 QEVDRIKE 902
QE D +K+
Sbjct: 929 QEKDDLKQ 936
Score = 94.4 bits (233), Expect = 5e-19
Identities = 143/743 (19%), Positives = 325/743 (43%), Gaps = 89/743 (11%)
Query: 210 LINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVIS-- 267
L+N+++E E ++K++ L + +++++ E L+ A+ +N++ + ++
Sbjct: 1143 LLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKER 1202
Query: 268 -ALAEGTKSYVPYRDSKMTRILQ-DSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAK 325
L E KS+ RD I + ++ G + + I + + E + T+ +R+
Sbjct: 1203 KVLKELQKSFETERDHLRGYIREIEATGLQTKEELKI----AHIHLKEHQETIDELRRSV 1258
Query: 326 TIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGE 385
+ K +N + + EK TK Q+E I L E N + V ET+ E
Sbjct: 1259 SEKTAQIINTQ----------DLEKSHTKLQEE-IPVLHEEQELLPNVKEVSETQETMNE 1307
Query: 386 EAALGAELCEETPVNDNSSIVVRIAPEER------QKYEEEIRRLYKQLDD--------- 430
EL E +S+ + RI E Q+ +EEI+ L K+ D+
Sbjct: 1308 -----LELLTEQSTTKDSTTLARIEMERLRLNEKFQESQEEIKSLTKERDNLKTIKEALE 1362
Query: 431 -KDDEINQQ-SQLIEKLKQQMLDQEELLVSTRGDNE--KVQRELSHLQSENDAAKDEVKE 486
K D++ + + + K+++ QE+ L DNE K+ E+ + ++ A E
Sbjct: 1363 VKHDQLKEHIRETLAKIQESQSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIE 1422
Query: 487 VLQALEELAVNYDQKSQEVEEKSQQNQLLV------DELSQKVATMLSLESELQRLQEVS 540
+L + L ++D+ +EK +L D+L + + +++ E + +V+
Sbjct: 1423 MLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQSESDQLKENIKEIVAKHLETEEELKVA 1482
Query: 541 GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPV---EISGAIEEEFTVARLYISKIKSE 597
K E +N L +LSE + + +L ++ I+E + + K SE
Sbjct: 1483 HCCLKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISE 1542
Query: 598 VKSVVKRCRQLEN--------LQVECHRKMEVTGRELSS---CQLLISQHEAKIRSLTEY 646
V+ V +Q + LQ + +E+T R S Q++I + E +
Sbjct: 1543 VQEKVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKE----EMKRV 1598
Query: 647 MQSVELKKRHLEESYDSLSDELAKLQAQET--VHEVALKDKEPDTQDADEVKKALELQME 704
+++++++ L+E+ + ++ + Q +E + A+ + + + + +K+ E Q
Sbjct: 1599 QEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKL 1658
Query: 705 S--HREAHHRQLARLRDEINEKQKTI----DELKDLNQKLQLELEKLQADYEKLKSEEHE 758
+ + E + +L ++ E E+ +++ D+L+ + + L++E ++L+ + + + + E
Sbjct: 1659 NLENIETENIRLTQILHENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLE 1718
Query: 759 KSTKLQELTFLYERHEQSKQDLKGLEETVARELQTL-----HNLRKLFVQDVTTR----- 808
K +L+ + + H+++ L+G+ E+ + H+ L QD+ +
Sbjct: 1719 KQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRI 1778
Query: 809 ----VKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKR 864
+K+ E + G + + K+S ++ +LE ++ +++ +L L+K
Sbjct: 1779 AHMHLKEQQETIDKLRGIVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKD 1838
Query: 865 LRATAERVKALEGALKEAKEGAM 887
+ T ++V +E K+ K+ ++
Sbjct: 1839 VNETQKKVSEMEQLKKQIKDQSL 1861
Score = 80.9 bits (198), Expect = 6e-15
Identities = 159/817 (19%), Positives = 319/817 (39%), Gaps = 139/817 (17%)
Query: 185 DEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGA 244
D+ K N V M E + + + E T++K+ +L + ++K++
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNE---TQEKMCEIEHLKEQFETQKLNLENI 1663
Query: 245 EGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMT-RILQDSLGGNCRTTM--- 300
E + + ++++L + +V TK R + T ++ +D L N R T+
Sbjct: 1664 ETENIRLTQILHENLEEMRSV-------TKERDDLRSVEETLKVERDQLKENLRETITRD 1716
Query: 301 --------FICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEK 352
+ + + K + ++ I N +LE + + K + K +E+
Sbjct: 1717 LEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQK-DLEHSNDALKAQDLKIQEE 1775
Query: 353 T-------KAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSI 405
K Q+ETI KL +S + + ++ A E +E N++ I
Sbjct: 1776 LRIAHMHLKEQQETIDKLRGIVSE--KTDKLSNMQKDLENSNAKLQEKIQELKANEHQLI 1833
Query: 406 VVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEK 465
++ E QK E+ +L KQ+ D QS + KL+ + L+ + L + +
Sbjct: 1834 TLKKDVNETQKKVSEMEQLKKQIKD-------QSLTLSKLEIENLNLAQKLHENLEEMKS 1886
Query: 466 VQRELSHLQSENDAAK---DEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQK 522
V +E +L+ + K D++KE LQ + + Q+ + S++++ VD+L +K
Sbjct: 1887 VMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1946
Query: 523 VATMLSLESELQR-LQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIE 581
++ S++Q+ L + +K+I E+ K+L V + ++
Sbjct: 1947 ISEKTIQISDIQKDLDKSKDELQKKIQELQK---KELQLLRVKEDVNMSHKKINEMEQLK 2003
Query: 582 EEFTVARLYISKIKSEVKSVVKRCRQ-LENLQVECHRKMEVTGRELSSCQLLISQHEAKI 640
++F L + ++ + + K+ + LE +++ + E+ R S ++ Q A +
Sbjct: 2004 KQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELR-RIKESLKMERDQFIATL 2062
Query: 641 RSLT---EYMQSVELKKRHLEESYDSLSD----------ELAKLQAQETVHEVALKDKEP 687
R + V+ +KR L + L++ EL K ++ H L
Sbjct: 2063 REMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNRLSL 2122
Query: 688 DTQDADEVKKALELQ--------------------------MESHR-------------- 707
D + E +K L ++ ME HR
Sbjct: 2123 DLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLSYVTK 2182
Query: 708 --EAHHRQLARLR----DEINEKQKTI---------------DELKDL--NQKLQLELEK 744
E H + + DE+ EKQK + EL+DL NQ + L +E+
Sbjct: 2183 IKEEQHESINKFEMDFIDEV-EKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEE 2241
Query: 745 LQADYEK-----LKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRK 799
+ D+ + +K+E + + +E+T E ++ D++ L+ + +E + +
Sbjct: 2242 ILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNN 2301
Query: 800 LFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELP 859
F + + +S E E + +Q + L+ E+L K ++ L A P
Sbjct: 2302 FFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSLASGAQVNP 2361
Query: 860 KLE---------KRLRATAERVKALEGALKEAKEGAM 887
+ + + T E+++ LE +L EAKE AM
Sbjct: 2362 TTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESAM 2398
Score = 78.2 bits (191), Expect = 4e-14
Identities = 173/825 (20%), Positives = 346/825 (41%), Gaps = 115/825 (13%)
Query: 152 TNLSVHEDKNRVPFVKGCTERFVSSPE---EILDVIDEGKSNRHVAVTNMNEHSSRSHSI 208
TN++ K + ++ E S + LD + E + N + N S +S+
Sbjct: 444 TNITTKTHKLSINLLREIDESVCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNSL 503
Query: 209 ------FLINIKQ---ENMETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSL 259
+++ +Q E E E KL K L + E+ +K E ++ E N+ +
Sbjct: 504 RADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNLKNLV 563
Query: 260 SALGNVISALAEGTKSYVPYRDSKMTRI--LQDSLGGNC--RTTMFICCSPSSYNDAETK 315
L S V K +I LQ+ + M + S S D +
Sbjct: 564 KHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQM 623
Query: 316 STLMFGQRAKTIKNTA--------SVNLEL---------TAEQWKKKYEKEKEKTKAQKE 358
+F A+T+ A S NLEL T +Q + + + + +A+K+
Sbjct: 624 KQTLFD--AETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEAKKK 681
Query: 359 TIAKLEAELSRWRN---------GENVPE----TERLAGEEAALGAELCEETPVNDNSSI 405
LE EL N VP+ L G+ L EL +E N+
Sbjct: 682 MQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEALRE 741
Query: 406 VVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEK 465
V I E + E+ RL K++ DK +E++ + +KL +++ +E + + K
Sbjct: 742 EV-ILLSELKSLPSEVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGK 800
Query: 466 VQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEV-EEKSQQNQLLVD---ELSQ 521
+ +L+ QS + E Q + L ++++QK + V EE + NQ +V+ E +
Sbjct: 801 TKDDLATTQSNYKSTDQE----FQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQK 856
Query: 522 KVATMLSLESEL----QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEIS 577
+++ +L++EL Q LQE + ++R+ E M+ L E +++
Sbjct: 857 FDSSLGALKTELSYKTQELQEKTREVQERLNE-----MEQLKE--------QLENRDSTL 903
Query: 578 GAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHE 637
+E E T+ + + EVK++ + L+ LQ +++ +L S +
Sbjct: 904 QTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQ----ESLQIERDQLKSD--IHDTVN 957
Query: 638 AKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKK 697
I + + ++E K+H +E+ ++L ++ ++E + +++ +T+D + +K
Sbjct: 958 MNIDTQEQLRNALESLKQH-QETINTLKSKI----SEEVSRNLHMEENTGETKDEFQ-QK 1011
Query: 698 ALELQMESHREAHHRQ--LARLRD-EINEKQKTIDELKDLNQKLQLELEKLQADYEKLKS 754
+ + + EA + Q A ++D EI E+Q+ I L +LQ LE + A+ E+LK+
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1071
Query: 755 EEHEKSTKLQELTFLYERHEQSK---QDLKGLEETVARELQTLHNLRKL--------FVQ 803
+ E + E E+ + +LK +E VA+E H ++K +
Sbjct: 1072 DLKE------NIEMTIENQEELRLLGDELKKQQEIVAQEKN--HAIKKEGELSRTCDRLA 1123
Query: 804 DVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADL---RCELPK 860
+V ++K+ ++ E + + ++++S ++ + ++ + +L L E +
Sbjct: 1124 EVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLE 1183
Query: 861 LEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVR 905
L ++L E VK++ K KE ++ ++ E D ++ +R
Sbjct: 1184 LAQKLNENYEEVKSITKERKVLKE----LQKSFETERDHLRGYIR 1224
Score = 71.6 bits (174), Expect = 4e-12
Identities = 141/692 (20%), Positives = 281/692 (40%), Gaps = 101/692 (14%)
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAEL--SRWRNGENVPETERLAGEEAALGA 391
NL E K + ++ KE + K +++ EL +R + E+ ++L + +
Sbjct: 1893 NLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTI 1952
Query: 392 ELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLD 451
++ + D S ++ +E QK E ++ R+ + ++ +IN+ QL ++ + Q L
Sbjct: 1953 QISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNMSHKKINEMEQLKKQFEAQNLS 2012
Query: 452 QEELLVSTRGDNEK----------VQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQK 501
+ + + +K V +E L+ ++ K E + + L E+ Q
Sbjct: 2013 MQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQN 2072
Query: 502 SQEVEEK---SQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDL 558
Q EK S Q L + L +K + + L L+R E+ H E LN L DL
Sbjct: 2073 HQVKPEKRLLSDGQQHLTESLREKCSRIKEL---LKRYSEMDDHY-----ECLNRLSLDL 2124
Query: 559 SEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRK 618
+ EI+ E+S ++ ++ L + K + K + +E HR
Sbjct: 2125 EK--------EIEFQKELSMRVKANLSLPYL-------QTKHIEKLFTANQRCSMEFHRI 2169
Query: 619 MEVTGRELSSC-QLLISQHEAKIRSLTEYMQSVELKK------RHLEESYDSLSDELAKL 671
M+ LS ++ QHE+ + +++ VE +K +HL++ D S EL L
Sbjct: 2170 MKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDL 2229
Query: 672 QAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDEL 731
+ + + ++ +++ D +++ E Q ++ +++ + +E + I++L
Sbjct: 2230 KLNQNM-DLHIEEILKDFSESEFPSIKTEFQQVL---SNRKEMTQFLEEWLNTRFDIEKL 2285
Query: 732 KDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERH-EQSKQDLKGLEETVARE 790
K+ QK + ++ + +ST+ +E + + EQ + LK E + +
Sbjct: 2286 KNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKN 2345
Query: 791 LQTLHNLRKLFVQ-DVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQ---------- 839
QTL Q + TT+ K+ + S +KI LEN+L +
Sbjct: 2346 YQTLKTSLASGAQVNPTTQDNKNPHVT---SRATQLTTEKIRELENSLHEAKESAMHKES 2402
Query: 840 -LTKVHKQLVRDN---ADLRCELPKLEKRLRATAERVKALEGAL-------KEAKEGA-- 886
+ K+ K+L N A L+ ++ + K L T E ++ L+ + KE E
Sbjct: 2403 KIIKMQKELEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKM 2462
Query: 887 ---------MKDKRRYQQEVDRIKEAVRY--------KSSGKRGHSAQIAKPVRPGHYPA 929
MK+ + +++E+ K V Y + + +R AQ +
Sbjct: 2463 KLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVI------- 2515
Query: 930 SSPTNPYGTRSPECISYTNSLFQNYQNLYLQA 961
S T+P + P + + QN + L L++
Sbjct: 2516 SEHTDPQPSNKPLTCGGGSGIVQNTKALILKS 2547
Score = 50.8 bits (120), Expect = 6e-06
Identities = 143/706 (20%), Positives = 277/706 (39%), Gaps = 126/706 (17%)
Query: 178 EEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYL------- 230
EE+ V+ E + R V T E S L K ++E +Q+L L
Sbjct: 1882 EEMKSVMKERDNLRRVEETLKLERDQLKES--LQETKARDLEIQQELKTARMLSKEHKET 1939
Query: 231 VDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQD 290
VD EK+S+ + + D K+++KS L I L + ++ ++ R+ +D
Sbjct: 1940 VDKL-REKISEKTIQ--ISDIQKDLDKSKDELQKKIQELQK--------KELQLLRVKED 1988
Query: 291 SLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYE--- 347
+ S N+ E F + ++++ N +LT + + E
Sbjct: 1989 -----------VNMSHKKINEMEQLKK-QFEAQNLSMQSVRMDNFQLTKKLHESLEEIRI 2036
Query: 348 --KEKEKTKAQKET--------IAKLEAELSRWRNGENVPETERLAGEEAALGAELCEET 397
KE+++ + KE+ IA L ++R R V +RL
Sbjct: 2037 VAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRL--------------- 2081
Query: 398 PVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLV 457
++D + E+ + +E ++R Y ++DD + +N+ S +EK ++ Q+EL +
Sbjct: 2082 -LSDGQQHLTESLREKCSRIKELLKR-YSEMDDHYECLNRLSLDLEK---EIEFQKELSM 2136
Query: 458 STRGDNEKVQRELSHLQ---SENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQL 514
+ + + H++ + N E +++ L+ + ++Y K +E E+ N+
Sbjct: 2137 RVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYV-LSYVTKIKE-EQHESINKF 2194
Query: 515 LVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLP- 573
+D + + V L ++Q LQ+ + + ++ DL ++ E + P
Sbjct: 2195 EMDFIDE-VEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLHIEEILKDFSESEFPS 2253
Query: 574 --VEISGAIE---------EEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVT 622
E + EE+ R I K+K+ ++ R Q+ N +
Sbjct: 2254 IKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRICQVNNFFNNRIIAIMNE 2313
Query: 623 GRELSSCQLLISQH-EAKIRSLTEYMQSVELKKRHLEESYDSLSDELAK-LQAQETVHEV 680
E IS+ E ++SL E K L ++Y +L LA Q T
Sbjct: 2314 STEFEERSATISKEWEQDLKSLKE-------KNEKLFKNYQTLKTSLASGAQVNPTTQ-- 2364
Query: 681 ALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQL 740
D ++ +A +L E RE L + ++E +++ + K+Q
Sbjct: 2365 -------DNKNPHVTSRATQLTTEKIRE--------LENSLHEAKESAMHKESKIIKMQK 2409
Query: 741 ELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVAREL----QTLHN 796
ELE KL+++ HE + L E++K+ ++ L++ VA + + +
Sbjct: 2410 ELEVTNDIIAKLQAKVHESNKCL----------EKTKETIQVLQDKVALGAKPYKEEIED 2459
Query: 797 LRKLFVQDVTTRVKKSAEMEPEDS---GGIHSQKQKISFLENNLEQ 839
L+ V+ ++K + E E E S + QK+ I L NL +
Sbjct: 2460 LKMKLVKIDLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRR 2505
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 280 bits (715), Expect = 7e-75
Identities = 263/936 (28%), Positives = 439/936 (46%), Gaps = 123/936 (13%)
Query: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIF-QGDDSVVIG-GKPYVFDRVFPPNTT 58
M E ++V R RPL EI G + F G+ VV+G K + +D VF P+T
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTE 60
Query: 59 QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAR 114
QE+V++ ++K V GYN T+ AYGQT SGKT++M G Q +G+IPR+ +
Sbjct: 61 QEEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQ 120
Query: 115 DIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVT--KTNLSVHEDKNRVPFVKGCTER 172
+F I + EF +KVSY EIY ++I DLL + K +++ ED + G TE+
Sbjct: 121 LLFKEI-DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEK 179
Query: 173 FVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQ-ENMETEQKLSGKLYLV 231
V + + +++G ++R VA T MN SSRSH+IF I+++Q + + KL+LV
Sbjct: 180 TVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLV 239
Query: 232 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-YVPYRDSKMTRILQD 290
DLAGSE+ KT AEG L E NIN+ L LGNVISAL + K +VPYRDSK+TR+LQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQD 299
Query: 291 SLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEK 350
SLGGN T M C SP+ N ET +TL + RA+ IKN VN++ + E
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLNTLRYADRARKIKNKPIVNID------PQTAELNH 353
Query: 351 EKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIA 410
K + Q+ + L+A V +E L ++ + N S+V
Sbjct: 354 LKQQVQQLQVLLLQAHGGTLPGSITVEPSENL-------------QSLMEKNQSLV---- 396
Query: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
EE +K + + Q +Q++E+ ++ T NEK+ +L
Sbjct: 397 -EENEKLSRGL----------SEAAGQTAQMLER-----------IILTEQANEKMNAKL 434
Query: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQK-------- 522
L+ ++ A K +++++++ LE DQ+ +E E Q L+ +LS +
Sbjct: 435 EELR-QHAACKLDLQKLVETLE------DQELKENVEIICNLQQLITQLSDETVACMAAA 487
Query: 523 VATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEE 582
+ T + E++++ E S R A ++ +V E+ + + A+
Sbjct: 488 IDTAVEQEAQVETSPETS---RSSDAFTTQHALRQAQMSKELV---ELNKALALKEALAR 541
Query: 583 EFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRS 642
+ T + I+ + + +K +LE + ++ E EL + + ++AK+
Sbjct: 542 KMTQNDSQLQPIQYQYQDNIK---ELELEVINLQKEKEELVLELQTAKK--DANQAKLS- 595
Query: 643 LTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQ 702
E +++ L+E ++D KL Q + LK KE + ++ + + +
Sbjct: 596 --------ERRRKRLQELEGQIADLKKKLNEQSKL----LKLKESTERTVSKLNQEIRM- 642
Query: 703 MESHREAHHRQL----ARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEK------L 752
M++ R RQ+ + R +K K + +LK+ ++K Q EL KL+ +++K
Sbjct: 643 MKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRR 702
Query: 753 KSEEHEKSTKLQELTFLYERHEQSKQ---DLKGLEETVARELQTLHNLRKLFVQDVTTRV 809
K+EE + K + +R K+ +G+E T AR L N ++ V T
Sbjct: 703 KTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVS--TEEA 760
Query: 810 KKSAEMEPED----SGGIHSQKQKISFLEN-------NLEQLTKVHKQLVRDNADLRCEL 858
K+ ED + + K+K EN LT+V Q+ + ++
Sbjct: 761 KRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSESEDSITKQI 820
Query: 859 PKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQ 894
LE + + ++ L+ L +A E + K+R++
Sbjct: 821 ESLETEMEFRSAQIADLQQKLLDA-ESEDRPKQRWE 855
Score = 50.8 bits (120), Expect = 6e-06
Identities = 95/463 (20%), Positives = 193/463 (41%), Gaps = 82/463 (17%)
Query: 341 QWKKKYEKE----KEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEE 396
QWK+K +KE KE+ + ++ + KLE RN + R EEAA + ++
Sbjct: 663 QWKQKKDKEVIQLKERDRKRQYELLKLE------RNFQKQSNVLRRKTEEAAAANKRLKD 716
Query: 397 TPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIE----KLKQQMLDQ 452
L KQ + D QS+ +E ++K + ++
Sbjct: 717 A--------------------------LQKQREVADKRKETQSRGMEGTAARVKNWLGNE 750
Query: 453 EELLVSTRGDNEKVQRELSHLQSENDAAKDEV---KEVLQALEELAVNYDQKSQEVEEKS 509
E++VST E+ +R L+ L + +V KE ++ E +++ + E
Sbjct: 751 IEVMVST----EEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVR 806
Query: 510 QQNQLLVDELSQKVATMLSLESELQ-RLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNG 568
Q D +++++ SLE+E++ R +++ Q+K + K E +
Sbjct: 807 GQVSESEDSITKQIE---SLETEMEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEA 863
Query: 569 EIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSS 628
+ L I E +++ +SK++S +K C ++ + E EL +
Sbjct: 864 KCALKYLIG-----ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQA 918
Query: 629 CQLLISQ-HEAKIRSLTEYMQSVELKKRHLEESYDSLSDE-LAKLQAQ----ETVHEVAL 682
+ + Q H+ K+ L +Q ++ ++ LEES + L+ L+ Q E + EV
Sbjct: 919 ELVRMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCE 978
Query: 683 KDKEPDTQDADEVKKALELQMESHREAH------------------HRQLARLRDEINEK 724
++++ ++ + +K+ L L + R+ H + +R++++ E+
Sbjct: 979 QNQQL-LRENEIIKQKLTLLQVASRQKHLPKDTLLSPDSSFEYVPPKPKPSRVKEKFLEQ 1037
Query: 725 QKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELT 767
I++LK ++ E E D ++ EE K TKL +++
Sbjct: 1038 SMDIEDLKYCSEHSVNEHEDGDGDDDEGDDEEW-KPTKLVKVS 1079
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 277 bits (708), Expect = 4e-74
Identities = 267/952 (28%), Positives = 448/952 (47%), Gaps = 77/952 (8%)
Query: 1 MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIF-QGDDSVVIG-GKPYVFDRVFPPNTT 58
M E ++V R RPL EI G + F G+ VV+G K + +D VF P T
Sbjct: 1 MKEEVKGIPVRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTE 60
Query: 59 QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ----LMGIIPRIAR 114
QE+V++ ++K + GYN T+ AYGQT SGKT++M G Q +GIIPR+ +
Sbjct: 61 QEEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQ 120
Query: 115 DIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVT--KTNLSVHEDKNRVPFVKGCTER 172
+F I + EF +KVSY EIY ++I DLL + K +++ ED + G TE+
Sbjct: 121 LLFKEI-DKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEK 179
Query: 173 FVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ-KLSGKLYLV 231
V + + +++G ++R VA T MN SSRSH+IF I+I+Q + KL+LV
Sbjct: 180 TVLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLV 239
Query: 232 DLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK-SYVPYRDSKMTRILQD 290
DLAGSE+ KT AEG L E NIN+ L LGNVISAL + K S+VPYRDSK+TR+LQD
Sbjct: 240 DLAGSERQKKTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQD 299
Query: 291 SLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLE-LTAEQWKKKYEKE 349
SLGGN T M C SP+ N ET STL + RA+ IKN VN++ TAE K + +
Sbjct: 300 SLGGNSHTLMIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQ 359
Query: 350 KEKT---KAQKETI-AKLEAELSR------WRNGENVPETERLA---GEEAALGAELCEE 396
+ + +A T+ + AE S +N V E E+L+ + A A++ E
Sbjct: 360 QLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLER 419
Query: 397 TPVNDNSSIVVRIAPEERQKY---EEEIRRLYKQLDDKDDEINQQ-----SQLIEKLKQQ 448
+ + + + EE +++ + ++++L + L+D++ + N + QLI +L +
Sbjct: 420 IILTEQVNEKLNAKLEELRQHVACKLDLQKLVETLEDQELKENVEIICNLQQLITQLSDE 479
Query: 449 MLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDE--------VKEVLQALEELAVNYDQ 500
+ + T + E +DA + KEV++ LA+
Sbjct: 480 TVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALAL---- 535
Query: 501 KSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSE 560
K V + +Q + L Q + +LE E+ LQ+ +++ + L K++++
Sbjct: 536 KEALVRKMTQNDNQLQPIQFQYQDNIKNLELEVINLQK----EKEELVRELQTAKKNVNQ 591
Query: 561 FSVIVGNGEIKLPVEISGAIEE--EFTVARLYISKIKSEVKSVVKRCRQ----LENLQVE 614
+ KL E+ G I + + + + K+K + V + Q ++N +V+
Sbjct: 592 AK--LSEHRHKLLQELEGQIADLKKKLNEQSKLLKLKESTERTVSKLNQEIWMMKNQRVQ 649
Query: 615 CHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQ 674
R+M+ + + + + ++ L E + + + LE ++ S L + +
Sbjct: 650 LMRQMKEDAEKFRQWK---QKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEE 706
Query: 675 ETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDL 734
LKD ++ + +K E Q R L +EI T + + L
Sbjct: 707 AAAANKRLKDALQKQREVTDKRK--ETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHL 764
Query: 735 NQKLQLELEKLQADYEKLKSEEHEKST---KLQELTF-LYERHEQSKQDLKGLEETVARE 790
N L+ + + L D +LK ++ + KL++ TF L E H Q + E+ + ++
Sbjct: 765 NDLLE-DRKILAQDVVQLKEKKESRENPPPKLRKCTFSLSEVHGQVLES----EDCITKQ 819
Query: 791 LQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRD 850
+++L +L + +K + E ED KQ + LE + K L+ +
Sbjct: 820 IESLETEMELRSAQIADLQQKLLDAESED-----RPKQCWENIATILEAKCAL-KYLIGE 873
Query: 851 NADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKE 902
+ + KLE LR + ++ L E + + + Q E+ R+++
Sbjct: 874 LVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQ 925
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 270 bits (690), Expect = 5e-72
Identities = 245/925 (26%), Positives = 421/925 (45%), Gaps = 143/925 (15%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKFIP-IFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
+C +KV R RP E + G + G+ V++G K + +D VF +T QEQ+Y
Sbjct: 6 DCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQEQIYS 65
Query: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLH---DPQLMGIIPRIARDIFNHIY 121
C ++++ GYN T+ AYGQT +GKT+TM + GIIPR +F I
Sbjct: 66 TCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHLFGGIA 125
Query: 122 SMDENL--------EFHIKVSYFEIYLDKIRDLLDVTK--------TNLSVHEDKNRVPF 165
EF + + E+Y ++I DL D T+ +N+ +HED N +
Sbjct: 126 ERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDANGGIY 185
Query: 166 VKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE---- 221
G T R + S EE++ + +G +R A T MN SSRSH+IF I++ Q M T+
Sbjct: 186 TTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCTQPDLV 245
Query: 222 -----------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGN 264
+ L+ K + VDLAGSE++ +TGA G E +IN L ALGN
Sbjct: 246 NEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGN 305
Query: 265 VISALAEGTKS--YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQ 322
VISAL + +K +VPYRDSK+TR+LQDSLGGN +T M C SPS + ET +TL +
Sbjct: 306 VISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYAN 365
Query: 323 RAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERL 382
RA+ IKN VN + T++Q A + IA+L+ EL ++ G +R+
Sbjct: 366 RARNIKNKVVVNQDKTSQQ-----------ISALRAEIARLQMELMEYKAG------KRV 408
Query: 383 AGEEAALG-AELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKD--------- 432
GE+ A G ++L E + + +R+ + Q+ + I QL ++
Sbjct: 409 IGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAKAG 468
Query: 433 DEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQ------------------ 474
D LI+ +++ + L+ + NE ++R LS
Sbjct: 469 DGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAFGG 528
Query: 475 ---SENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLES 531
S + A + ++ Q LE L K +EV ++ + + + K+ S E+
Sbjct: 529 SPASSMEDASEVIRRAKQDLERL------KKKEVRQRRKSPEKEAFKKRAKLQQENSEET 582
Query: 532 ELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYI 591
+ +E + + E G +D E S G + V+ EE+ + +
Sbjct: 583 DENEAEEEEEERDESGCEEEEG-REDEDEDS-----GSEESLVDSDSDPEEKEVNFQADL 636
Query: 592 SKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVE 651
+ + E++ K +LEN Q R++ Q L Q+E K+ L ++ +
Sbjct: 637 ADLTCEIEIKQKLIDELENSQ----RRL----------QTLKHQYEEKLILLQNKIRDTQ 682
Query: 652 LKKRHLEESYDSL----SDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHR 707
L++ + ++ ++ ++ K++A +E L++ D Q +K ++ ++
Sbjct: 683 LERDRVLQNLSTMECYTEEKANKIKAD---YEKRLREMNRDLQKLQAAQKE-HARLLKNQ 738
Query: 708 EAHHRQLARLRDEINEKQKT----IDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKL 763
+ R+L +L+ E+ E +K + ++++ Q+ +L K + +LK E+ + ++
Sbjct: 739 SRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQI 798
Query: 764 QELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPE--DSG 821
+ L Q +Q E + R+ Q + LR+L + ++ RV A ++P DSG
Sbjct: 799 RAL------ESQKRQQ----EMVLRRKTQEVSALRRL-AKPMSERVAGRAGLKPPMLDSG 847
Query: 822 GIHSQKQKISFLENNLEQLTKVHKQ 846
S S E+ ++ + +Q
Sbjct: 848 AEVSASTTSSEAESGARSVSSIVRQ 872
Score = 53.5 bits (127), Expect = 1e-06
Identities = 114/542 (21%), Positives = 234/542 (43%), Gaps = 47/542 (8%)
Query: 252 AKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQ-DSLGGNCRTTMFICCSPSSYN 310
++ N L+ G+ A+ ++Y+ + T++L+ +++ + R ++ + S Y+
Sbjct: 457 SQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYS 516
Query: 311 DAETKSTLMFG-QRAKTIKNTASV--NLELTAEQWKKKYEKEKEKTKAQKETI---AKLE 364
+ + FG A ++++ + V + E+ KKK +++ K+ +KE AKL+
Sbjct: 517 LGASPAAPAFGGSPASSMEDASEVIRRAKQDLERLKKKEVRQRRKSP-EKEAFKKRAKLQ 575
Query: 365 AELSRWRNGENVPETERLAGEEAAL----GAELCEETPVNDNSSIVVRIAPEERQ-KYEE 419
E S EN E E +E+ G E +E ++ S + PEE++ ++
Sbjct: 576 QENSE-ETDENEAEEEEEERDESGCEEEEGREDEDEDSGSEESLVDSDSDPEEKEVNFQA 634
Query: 420 EIRRLYKQLDDKD---DEINQQSQLIEKLKQQMLDQEELLVS----TRGDNEKVQRELSH 472
++ L +++ K DE+ + ++ LK Q ++ LL + T+ + ++V + LS
Sbjct: 635 DLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLERDRVLQNLST 694
Query: 473 LQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESE 532
++ + +++K +Y+++ +E+ Q+ Q E ++ + E E
Sbjct: 695 MECYTEEKANKIK----------ADYEKRLREMNRDLQKLQAAQKEHARLLKNQSRYERE 744
Query: 533 LQRLQ-EVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEE----EFTVA 587
L++LQ EV+ ++ ++A LMK + E E K EI+ +E EF +
Sbjct: 745 LKKLQAEVAEMKKAKVA-----LMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIR 799
Query: 588 RLYISKIKSEVKSVVKRCRQLENLQVECHRKME--VTGRELSSCQLLISQHEAKIRSLTE 645
L K + E+ V++R Q + + M V GR +L S E + +
Sbjct: 800 ALESQKRQQEM--VLRRKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSGAEVSASTTSS 857
Query: 646 YMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADE-VKKALELQME 704
+S + ++ + TV+ K+ + A + KA L+ +
Sbjct: 858 EAESGARSVSSIVRQWNRKINHFLGDHPAPTVNGTRPARKKFQKKGASQSFSKAARLKWQ 917
Query: 705 SHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQ 764
S E + R I + ++ L ++L L E L+ E+L++E E+ LQ
Sbjct: 918 S-LERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQEALRRKRERLQAESPEEEKGLQ 976
Query: 765 EL 766
EL
Sbjct: 977 EL 978
Score = 50.1 bits (118), Expect = 1e-05
Identities = 111/530 (20%), Positives = 213/530 (40%), Gaps = 91/530 (17%)
Query: 400 NDNSSIVVRIAPEERQ--------KYEEEIRRLYKQLDDKDDEINQQ-SQLIEKLKQQML 450
N + ++ ++P +R KY R + ++ D+ +QQ S L ++ + +
Sbjct: 338 NSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIARLQM 397
Query: 451 DQEELLVSTRGDNEK-------VQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQ 503
+ E R E + RE + LQ EN A + VK + +A++ + Q
Sbjct: 398 ELMEYKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMS 457
Query: 504 EVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLN-GLMKDLSEFS 562
+ + N LL A +++ ++ ++E+ + +E +N L + LS S
Sbjct: 458 Q-----EANLLLAKAGDGNEAIGALIQNYIREIEEL--RTKLLESEAMNESLRRSLSRAS 510
Query: 563 VIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVT 622
+ P + GA S ++ + V++R +Q +E +K EV
Sbjct: 511 A-------RSPYSL-GASPAAPAFGGSPASSME-DASEVIRRAKQ----DLERLKKKEVR 557
Query: 623 GRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVAL 682
R S + EA + + +L++ + EE+ ++ ++E + + + E
Sbjct: 558 QRRKSP------EKEA-------FKKRAKLQQENSEETDENEAEEEEEERDESGCEEEEG 604
Query: 683 KDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLEL 742
++ E + ++E + E LA L EI KQK IDEL++ ++LQ
Sbjct: 605 REDEDEDSGSEESLVDSDSDPEEKEVNFQADLADLTCEIEIKQKLIDELENSQRRLQT-- 662
Query: 743 EKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFV 802
LK + EK LQ R Q ++D R LQ L + + +
Sbjct: 663 ---------LKHQYEEKLILLQNKI----RDTQLERD---------RVLQNLSTM-ECYT 699
Query: 803 QDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLE 862
++ ++K E + ++ QK L+ K H +L+++ + EL KL+
Sbjct: 700 EEKANKIKADYEKRLRE---MNRDLQK-------LQAAQKEHARLLKNQSRYERELKKLQ 749
Query: 863 KRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKR 912
+ AE KA +K+ +E + +RR E R +E + K +R
Sbjct: 750 AEV---AEMKKAKVALMKQMRE---EQQRRRLVETKRNREIAQLKKEQRR 793
Score = 33.5 bits (75), Expect = 1.1
Identities = 68/297 (22%), Positives = 114/297 (38%), Gaps = 44/297 (14%)
Query: 323 RAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRW--RNGENVPETE 380
R K K AS + A + E+ Q+ TI LEA++ R + E E
Sbjct: 896 RKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKREELFLLQE 955
Query: 381 RLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQ 440
L + L AE EE + Q+ EEI L +D +D I
Sbjct: 956 ALRRKRERLQAESPEEE--------------KGLQELAEEIEVLAANIDYINDGITDCQA 1001
Query: 441 LIEKLKQ--QMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNY 498
I +L++ + LD + V + R L L + A+ D+ +V Q ++ +
Sbjct: 1002 TIVQLEETKEELDSTDTSVVISSCSLAEARLL--LDNFLKASIDKGLQVAQKEAQIRLLE 1059
Query: 499 DQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDL 558
+ Q S QN LL+D L +K L++ + +Q+ +G+ +++
Sbjct: 1060 GRLRQTDMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYA---------STDEEI 1110
Query: 559 SEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVEC 615
SEFS G+ + FT+ + S + KS K Q++ + EC
Sbjct: 1111 SEFS--------------EGSFSQSFTM-KGSTSHDDFKFKSEPKLSAQMKAVSAEC 1152
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 270 bits (689), Expect = 7e-72
Identities = 269/908 (29%), Positives = 431/908 (47%), Gaps = 89/908 (9%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFI----PIFQGDDSVVIGG-------KPYVFDRVFPPNT 57
+I+V+ R RP N AE I P+ + + SV GG K Y FD VF +T
Sbjct: 18 NIQVVVRCRPFNLAERKASAHSIVECDPV-RKEVSVRTGGLADKSSRKTYTFDMVFGAST 76
Query: 58 TQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKL---------HDPQLMGI 108
Q VY + I+ +V+ GYN TIFAYGQT +GKT TMEG+ DP L GI
Sbjct: 77 KQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP-LAGI 135
Query: 109 IPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVTKTNLSVHEDKN-RV 163
IPR IF + D EF +KVS EIY +++ DLL DV++ + +N R
Sbjct: 136 IPRTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRG 193
Query: 164 PFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINI--KQENMETE 221
+KG E V + +E+ ++++G + R A T MN +SSRSHS+F + I K+ ++ E
Sbjct: 194 VIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGE 253
Query: 222 QKLS-GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYR 280
+ + GKL LVDLAGSE + ++GA EA NIN+SL LG VI+AL E T +VPYR
Sbjct: 254 ELVKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTP-HVPYR 312
Query: 281 DSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAE 340
+SK+TRILQDSLGG RT++ SP+S N ET STL + RAK I N VN +LT +
Sbjct: 313 ESKLTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKK 372
Query: 341 QWKKKYEKEKEKTK-----AQKETIAKLEAELSRWRNGENVPETERLAGEEAALGA---E 392
K+Y +E E+ K A+++ + E R +G+ + E++ +GA E
Sbjct: 373 ALIKEYTEEIERLKRDLAAAREKNGVYISEENFRVMSGKLTVQEEQIVELIEKIGAVEEE 432
Query: 393 LCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQL---IEKLKQQM 449
L T + ++ + + Q +E+ K L + ++ ++ + +E ++++
Sbjct: 433 LNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVKEEYITSALESTEEKL 492
Query: 450 LDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEE-- 507
D L++T E+ +++S L S+ D K + +A + N + +EE
Sbjct: 493 HDAASKLLNT---VEETTKDVSGLHSKLDRKKAVDQHNAEAQDIFGKNLNSLFNNMEELI 549
Query: 508 ---KSQQNQLLV-------DELSQKVATMLSLES-ELQRLQEVSGHQRKRIAEVLNGLMK 556
S+Q +L + LS V+ + ++ + L L + + ++++ N ++K
Sbjct: 550 KDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLTSIPENVSTHVSQIFNMILK 609
Query: 557 DLS---EFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQV 613
+ S E ++ L ++ ++E + + I KI S++K + K + + ++
Sbjct: 610 EQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKINSQLKHIFKTSLTVAD-KI 668
Query: 614 ECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQA 673
E +K E+ G C L E I SL E + L+ + S EL KL
Sbjct: 669 E-DQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTEDLKTIKQTHSQELCKLMN 727
Query: 674 QETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKD 733
T AL++K + Q + E + ++ ++ + + EL++
Sbjct: 728 LWTERFCALEEKCENIQ--KPLSSVQENIQQKSKDIVNKMTFHSQKFCADSDGFSQELRN 785
Query: 734 LNQ---KLQLE----LEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEET 786
NQ KL E +KL + EK+ E ++ L T + S+Q + L E
Sbjct: 786 FNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYF-----SEQWVSSLNE- 839
Query: 787 VARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQ 846
RE Q LHNL ++ Q S E D +KQ F L+Q+T +
Sbjct: 840 --RE-QELHNLLEVVSQ--CCEASSSDITEKSDGRKAAHEKQHNIF----LDQMTIDEDK 890
Query: 847 LVRDNADL 854
L+ N +L
Sbjct: 891 LIAQNLEL 898
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 268 bits (685), Expect = 2e-71
Identities = 259/927 (27%), Positives = 425/927 (45%), Gaps = 121/927 (13%)
Query: 45 KPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104
K + FD V +TTQE V+ A IV+ ++GYNGTIFAYGQT SGKT TM G
Sbjct: 68 KTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDN 127
Query: 105 ----LMGIIPRIARDIFNHIYSMDENL----EFHIKVSYFEIYLDKIRDLLDVTKTNLSV 156
L G+IPR +F+ I E F K S+ EIY ++I DLLD L +
Sbjct: 128 FSHNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYL 187
Query: 157 HEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQE 216
E + FV G E+ V+S E V+ G NR VA T+MN SSRSH++F I I E
Sbjct: 188 REHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITI--E 245
Query: 217 NMETEQKL----SGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE- 271
+ME ++ + L LVDLAGSE+ T AEG L EA NIN+SLS LG VI+AL +
Sbjct: 246 SMEKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDV 305
Query: 272 --GTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKN 329
G + +V YRDSK+T +L+DSLGGN +T + P S ET STL F QRAK IKN
Sbjct: 306 GNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKN 365
Query: 330 TASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAAL 389
A VN E + + + +L+ +L+ +G+ PE+ ++
Sbjct: 366 KAVVN------------EDTQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTN 413
Query: 390 GAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQ-Q 448
E +E + + + + +E++ E++ +L + L K ++ Q +++I K ++ Q
Sbjct: 414 YMEYFQE------AMLFFKKSEQEKKSLIEKVTQL-EDLTLKKEKFIQSNKMIVKFREDQ 466
Query: 449 MLDQEELLVSTRGD--NEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYD------- 499
++ E+L +RG E+ R LS L++E +++++ + + N+
Sbjct: 467 IIRLEKLHKESRGGFLPEEQDRLLSELRNEIQTLREQIEHHPRVAKYAMENHSLREENRR 526
Query: 500 -------QKSQEVE-----------------EKSQQNQLLVDELSQKVATMLSLESELQR 535
+++QE++ EKS +NQ +QK + + +L+
Sbjct: 527 LRLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKA 586
Query: 536 LQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARL------ 589
Q +I LN ++ EF + +++L E+ + + L
Sbjct: 587 -------QLLQIQTELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKA 639
Query: 590 -------YISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRS 642
++KI +E ++ + L R + E+ S L +Q+ +
Sbjct: 640 CKRQEVSQLNKIHAETLKIITTPTKAYQLH---SRPVPKLSPEMGSFGSLYTQNSS---I 693
Query: 643 LTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQ 702
L + + + E++++++S+EL +Q Q + + L ++E K L+LQ
Sbjct: 694 LDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEE---------HKNLKLQ 744
Query: 703 MESHREAHH-RQLARL-RDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKS 760
+ HH Q+ L E + K +EL L+ +L++ Q + LKSE H+
Sbjct: 745 QHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLR 804
Query: 761 TKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEP--E 818
L + K +E +L H +L + ++ +K E + +
Sbjct: 805 VVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKACLQ 864
Query: 819 DSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGA 878
DS + Q+I E ++QL++ + ++N L+ +L L + L A ER L
Sbjct: 865 DS---YDNLQEIMKFE--IDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQ 919
Query: 879 LKEAKEGAMKDKRRYQQEVDRIKEAVR 905
+E KE + K E+ ++ EAVR
Sbjct: 920 FEEDKENSSK-------EILKVLEAVR 939
Score = 75.1 bits (183), Expect = 3e-13
Identities = 123/639 (19%), Positives = 255/639 (39%), Gaps = 90/639 (14%)
Query: 331 ASVNLELTAEQWKK-KYEKEKEKTKAQKETIAKLEAELSRWR-NGENVPETERLAGEEAA 388
A++NLE E K K ++ + K ET+ + ++ + VP +L+ E +
Sbjct: 626 ANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVP---KLSPEMGS 682
Query: 389 LGAELCEETPVNDNSSIVVRIAPE-----------ERQKYEEEIRRLYKQLDDKDDEINQ 437
G+ + + + DN + + PE E + +E++ L +LD+++ + +
Sbjct: 683 FGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLK 742
Query: 438 QSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL-----------SHLQSENDAAKDEVKE 486
Q ++KL+ +EL S R D K Q EL Q++ND K EV +
Sbjct: 743 LQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHD 802
Query: 487 VLQAL----EELA----------VNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESE 532
+ L +EL+ N +++ ++ E+ QL +D L + +L ++
Sbjct: 803 LRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKAC 862
Query: 533 LQ----RLQEVSGHQRKRIA----------EVLNGLMKDLSEFSVIVGNGEIKLPVEISG 578
LQ LQE+ + +++ E L + +L E KL ++
Sbjct: 863 LQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFEE 922
Query: 579 AIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEA 638
E + ++ E + +C Q + + T + +SS + +
Sbjct: 923 DKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKK 982
Query: 639 KIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQ-------ETVHEVALKDKEPDTQD 691
+ L +Q + E+ D+L EL + + V +K +E D D
Sbjct: 983 VVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVDILD 1042
Query: 692 ADEVKKALELQMESHREAHHRQLARLRDEIN--------------EKQKTIDELKDLNQK 737
E + L + R+ LA +++N Q+ + + + L Q+
Sbjct: 1043 LKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQE 1102
Query: 738 LQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLH-- 795
LQ +L + + + E+ K+E + K +L+ + QS + + +A+ L+T
Sbjct: 1103 LQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQE 1162
Query: 796 ----NLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDN 851
K ++ + T++ + E++ + I K+++ +EN L +QL+ N
Sbjct: 1163 IEDGRASKTSLEHLVTKLNEDREVK---NAEILRMKEQLREMEN----LRLESQQLIEKN 1215
Query: 852 ADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDK 890
L+ +L + KR + +++ LK +E ++K++
Sbjct: 1216 WLLQGQLDDI-KRQKENSDQNHPDNQQLKNEQEESIKER 1253
Score = 49.7 bits (117), Expect = 1e-05
Identities = 88/448 (19%), Positives = 190/448 (42%), Gaps = 63/448 (14%)
Query: 328 KNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETER------ 381
K +S + E +++ +KE K + Q + KLE L + E R
Sbjct: 924 KENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKV 983
Query: 382 ---LAGEEAALGAELCEETPVND-------------NSSIVVRIAPEERQKYEEEIRRLY 425
L + L +CE+T D NS++V R EE R L
Sbjct: 984 VADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDR----------EESRVLI 1033
Query: 426 KQLDDKDDEINQQSQL---IEKLKQQMLDQEELLVSTRGDNEKVQRELSH---LQSENDA 479
K+ + ++ + +L E +++ ML E+L +T N + H LQS
Sbjct: 1034 KKQEVDILDLKETLRLRILSEDIERDMLC-EDLAHATEQLNMLTEASKKHSGLLQS---- 1088
Query: 480 AKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEV 539
A++E+ + ++EL +QK +EVE+K + + +L ++ +E + +
Sbjct: 1089 AQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEH----VMDSAAEDPQSPKT 1144
Query: 540 SGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVK 599
H + +A++L +++ + G + + E+ V I ++K ++
Sbjct: 1145 PPHFQTHLAKLLETQEQEIED-----GRASKTSLEHLVTKLNEDREVKNAEILRMKEQL- 1198
Query: 600 SVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEE 659
R++ENL++E + +E + Q E ++ + Q ++ ++E
Sbjct: 1199 ------REMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKE 1252
Query: 660 --SYDSLSDELAKLQAQETVHEVALKDKEPD-TQDADEVKKALELQMESHREAHHRQLAR 716
+ + +E+ K++A + AL +KE + + DEV++ L+ ++ +E + ++
Sbjct: 1253 RLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLR-SK 1311
Query: 717 LRDEINEKQKTIDELKDLNQKLQLELEK 744
L + E+++T E++ L ++++ E+
Sbjct: 1312 LEEMYEERERTSQEMEMLRKQVECLAEE 1339
Score = 44.7 bits (104), Expect = 5e-04
Identities = 94/499 (18%), Positives = 215/499 (43%), Gaps = 66/499 (13%)
Query: 311 DAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEK-----EKEKTKAQKETIAKLEA 365
D +++ F + +T+K+ + +EL E K++ K E++K + KE + LEA
Sbjct: 879 DQLSRNLQNFKKENETLKSDLNNLMELL-EAEKERNNKLSLQFEEDKENSSKEILKVLEA 937
Query: 366 ELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLY 425
E ET + E+ + EE+ + V+ + R ++ + L
Sbjct: 938 VRQ-----EKQKETAKC--EQQMAKVQKLEESLLATEK--VISSLEKSRDSDKKVVADLM 988
Query: 426 KQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSH-LQSENDAAKDEV 484
Q+ + + ++++ I+ LKQ++ D ++ + ++ V RE S L + + ++
Sbjct: 989 NQIQELRTSVCEKTETIDTLKQELKD-----INCKYNSALVDREESRVLIKKQEVDILDL 1043
Query: 485 KEVLQA------------LEELAVNYDQKSQEVEEKSQQNQLLV---DELSQKVATMLSL 529
KE L+ E+LA +Q + E + + LL +EL++K A + L
Sbjct: 1044 KETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQEL 1103
Query: 530 ESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARL 589
+ +L + +E ++ N M+ L V + + P + +A+L
Sbjct: 1104 QHKLNQKKEEVEQKKNEY----NFKMRQLEH----VMDSAAEDPQSPKTPPHFQTHLAKL 1155
Query: 590 YISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQS 649
++ + E++ LE+L + + EV E+ +++ M++
Sbjct: 1156 LETQ-EQEIEDGRASKTSLEHLVTKLNEDREVKNAEI-----------LRMKEQLREMEN 1203
Query: 650 VELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDA-DEVKKALELQMESHRE 708
+ L+ + L E L +L ++ Q+ + PD Q +E +++++ ++ +
Sbjct: 1204 LRLESQQLIEKNWLLQGQLDDIKRQKENSD----QNHPDNQQLKNEQEESIKERLAKSKI 1259
Query: 709 AHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTF 768
++ +++ ++ E Q + + ++ E+E+ Q K E+ + +KL+E
Sbjct: 1260 VE--EMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEE--- 1314
Query: 769 LYERHEQSKQDLKGLEETV 787
+YE E++ Q+++ L + V
Sbjct: 1315 MYEERERTSQEMEMLRKQV 1333
Score = 39.3 bits (90), Expect = 0.019
Identities = 46/209 (22%), Positives = 94/209 (44%), Gaps = 17/209 (8%)
Query: 347 EKEKEKTKAQKETIAKLEAELSRWR---NGENVPETERLAGEEAAL--GAELCEETPVND 401
E+E E +A K ++ L +L+ R N E + E+L E +L E+ +
Sbjct: 1160 EQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKNWLLQ 1219
Query: 402 NSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEEL---LVS 458
++ E + + ++L + ++ E +S+++E++ + D EE+ L +
Sbjct: 1220 GQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLEEVQSALYN 1279
Query: 459 TRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDE 518
+ ++ E+ Q+ A E +++ LEE+ ++ SQE+E +Q + L +E
Sbjct: 1280 KEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEE 1339
Query: 519 ---------LSQKVATMLSLESELQRLQE 538
L QK+ ++ L+ E RL E
Sbjct: 1340 NGKLVGHQNLHQKIQYVVRLKKENVRLAE 1368
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 265 bits (677), Expect = 2e-70
Identities = 184/478 (38%), Positives = 261/478 (54%), Gaps = 38/478 (7%)
Query: 9 SIKVLCRFRPLNQAEI-LRGDKFIPI--------FQGDDSVVIGGKPYVFDRVFPPNTTQ 59
++KV+ R RP+NQ E LR + + Q + K + FD + +
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVT 64
Query: 60 EQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNH 119
EQ+Y+ A +V+ V GYNGTIFAYGQT SGK+ TM+G P GIIPR +F
Sbjct: 65 EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFES 124
Query: 120 IYSMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTERFVSSPE 178
+ EN +F ++ SY EIY + +RDLL TK L + E + +VKG + V S
Sbjct: 125 VQCA-ENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVA 183
Query: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQK---LSGKLYLVDLAG 235
+ +++ G NR V T MN+ SSRSHSIF I+I+ ++ K +GKL LVDLAG
Sbjct: 184 QCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAG 243
Query: 236 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGN 295
SE+ SKTGA G L EA IN SLSALGNVISAL +G +VPYRDSK+TR+LQDSLGGN
Sbjct: 244 SERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGN 303
Query: 296 CRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKA 355
+T M C SP+ N ET STL + RAK I+N +N E + ++Y++E +K KA
Sbjct: 304 TKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKLKA 362
Query: 356 ---QKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPE 412
Q+ + + L A LSR + V E+L + + V ++
Sbjct: 363 ILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVI-------QHDVEAEKQLI------ 409
Query: 413 ERQKYEEEIRRLYKQLDDKDDEINQQSQL-IEKLKQQMLDQEELLVSTRGDNEKVQRE 469
R++YEE + RL D + Q+S+ +E+ M + ++ +ST +N + + E
Sbjct: 410 -REEYEERLARL-----KADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETE 461
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 265 bits (677), Expect = 2e-70
Identities = 184/478 (38%), Positives = 261/478 (54%), Gaps = 38/478 (7%)
Query: 9 SIKVLCRFRPLNQAEI-LRGDKFIPI--------FQGDDSVVIGGKPYVFDRVFPPNTTQ 59
++KV+ R RP+NQ E LR + + Q + K + FD + +
Sbjct: 5 AVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVT 64
Query: 60 EQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNH 119
EQ+Y+ A +V+ V GYNGTIFAYGQT SGK+ TM+G P GIIPR +F
Sbjct: 65 EQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFES 124
Query: 120 IYSMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTERFVSSPE 178
+ EN +F ++ SY EIY + +RDLL TK L + E + +VKG + V S
Sbjct: 125 VQCA-ENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVA 183
Query: 179 EILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQK---LSGKLYLVDLAG 235
+ +++ G NR V T MN+ SSRSHSIF I+I+ ++ K +GKL LVDLAG
Sbjct: 184 QCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAG 243
Query: 236 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGN 295
SE+ SKTGA G L EA IN SLSALGNVISAL +G +VPYRDSK+TR+LQDSLGGN
Sbjct: 244 SERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGN 303
Query: 296 CRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKA 355
+T M C SP+ N ET STL + RAK I+N +N E + ++Y++E +K KA
Sbjct: 304 TKTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKLKA 362
Query: 356 ---QKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPE 412
Q+ + + L A LSR + V E+L + + V ++
Sbjct: 363 ILTQQMSPSSLSALLSRQVPPDPVQVEEKLLPQPVI-------QHDVEAEKQLI------ 409
Query: 413 ERQKYEEEIRRLYKQLDDKDDEINQQSQL-IEKLKQQMLDQEELLVSTRGDNEKVQRE 469
R++YEE + RL D + Q+S+ +E+ M + ++ +ST +N + + E
Sbjct: 410 -REEYEERLARL-----KADYKAEQESRARLEEDITAMRNSYDVRLSTLEENLRKETE 461
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 259 bits (663), Expect = 7e-69
Identities = 239/895 (26%), Positives = 412/895 (46%), Gaps = 129/895 (14%)
Query: 6 NECSIKVLCRFRPLNQAEILRGDKFIP-IFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVY 63
+E S++V R RP E + G + G+ V +G K + FD VF ++ QEQ+Y
Sbjct: 6 DESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIY 65
Query: 64 HACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL----MGIIPRIARDIFNH 119
C ++++ GYN T+FAYGQT +GKT+TM G D + +GII R + +F
Sbjct: 66 IQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFKS 124
Query: 120 I-----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVT--------KTNLSVHEDKNRV 163
I ++ L +F + + E+Y +++ DL D T K+N+ +HED
Sbjct: 125 IEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGG 184
Query: 164 PFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQEN------ 217
+ G T R V++ E++ + G +R A T MN SSRSH+IF I++ Q
Sbjct: 185 IYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQID 244
Query: 218 ---------------METEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSAL 262
M + L+ K + VDLAGSE++ +TGA G E +IN L AL
Sbjct: 245 ADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLAL 304
Query: 263 GNVISALAEGTK--SYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMF 320
GNVISAL + +K ++VPYRDSK+TR+LQDSLGGN +T M C SPS + ET +TL +
Sbjct: 305 GNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKY 364
Query: 321 GQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETE 380
RA+ IKN VN + ++Q A + I +L+ EL ++ G+ + + E
Sbjct: 365 ANRARNIKNKVMVNQDRASQQ-----------INALRSEITRLQMELMEYKTGKRIIDEE 413
Query: 381 RLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIR-RLYKQLDDKDDEI---- 435
+ +T +N+++ VRI + Q+ + +R R+ + + D+ + +
Sbjct: 414 GVESINDMFHENAMLQT---ENNNLRVRI--KAMQETVDALRSRITQLVSDQANHVLARA 468
Query: 436 ----NQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSEND------------- 478
+ S +I +++ D L+ + NE +++ L+ +
Sbjct: 469 GEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTIL 528
Query: 479 AAKDEVKEVL----QALEELAVNYDQKSQEVEEKSQQNQLLVDELSQK-VATMLSLESEL 533
++ E E++ + LE+L +K + V K ++ +K V+ + E E+
Sbjct: 529 SSDKETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEV 588
Query: 534 QRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISK 593
+ QEVS H+ + E E + GE + S + +E + ++
Sbjct: 589 EESQEVSDHEDEEEEE---------EEEEDDIDGGESS---DESDSESDEKANYQADLAN 636
Query: 594 IKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELK 653
I E+ K +LEN Q Q L Q+E K+ L ++ +L+
Sbjct: 637 ITCEIAIKQKLIDELENSQ--------------KRLQTLKKQYEEKLMMLQHKIRDTQLE 682
Query: 654 KRHLEE---SYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAH 710
+ + + S +S S+E AK E ++ +KE A + + A L+ +S E
Sbjct: 683 RDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYE-- 740
Query: 711 HRQLARLRDEINEKQKT----IDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQEL 766
+QL +L+ ++ E +KT + ++K+ +K +L + + +LK ++ ++ +L+ L
Sbjct: 741 -KQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLL 799
Query: 767 TFLYERHEQSKQDLKGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSG 821
++ Q + EE A Q K V TR S++ +D+G
Sbjct: 800 E--AQKRNQEVVLRRKTEEVTALRRQVRPMSDK--VAGKVTRKLSSSDAPAQDTG 850
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 257 bits (657), Expect = 3e-68
Identities = 292/1121 (26%), Positives = 479/1121 (42%), Gaps = 216/1121 (19%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVI------GG---------KPYVFDRVF 53
S+KV R RP+N+ E KFI + + + GG K + +D F
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 54 -------PPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
P +QE V+ +VK GYN +FAYGQT SGK++TM G D
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 107 GIIPRIARDIFNHIYSMD--ENLEFHIKVSYFEIYLDKIRDLL--DVTKT-NLSVHEDKN 161
G+IPRI +F+ I + F +VSY EIY +++RDLL +KT NL V E
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 162 RVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE 221
P+V+ ++ V + ++ +++D G NR A T MN+ SSRSH+IF I Q ++E
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
Query: 222 QKLS--GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS---- 275
K++LVDLAGSE+ TGA G L E NINKSL LGNVISALA+ ++
Sbjct: 240 MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
Query: 276 -------YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIK 328
+VPYRDS +T +L+DSLGGN +T M SP+ N ET STL + RAK I
Sbjct: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
Query: 329 NTASVN--------LELTAEQWKKK----------------YEKEKEKTKAQKETIAKLE 364
N ++N EL AE + K +EK + + + +L
Sbjct: 360 NKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELT 419
Query: 365 AE-LSRWRNGENVPETERLAGEEAALGAELCEETP----VNDN--SSIVVRIAPEERQKY 417
E ++W +N+ + + LA + +G L E P ++D+ S+ ++ +E Q Y
Sbjct: 420 KEWTNKWNETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTY 479
Query: 418 --------EEEIRRLYKQLDDKD---DEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKV 466
E++I L+ + + I LI Q +V N+
Sbjct: 480 VGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGA 539
Query: 467 -----QRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVE--------------E 507
+ + +AAK K L +++ S+ E E
Sbjct: 540 VILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNPGLEFE 599
Query: 508 KSQQNQL--------LVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLS 559
+ Q+ +L L++E+ +K S ++EL+R+Q+ QRK V + K
Sbjct: 600 RQQREELEKLESKRKLIEEMEEK---QKSDKAELERMQQEVETQRKETEIVQLQIRK--Q 654
Query: 560 EFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQV--ECHR 617
E S+ + I+ ++ A +E+F RL + + E++ KR + L+V E R
Sbjct: 655 EESLKRRSFHIENKLKDLLAEKEKFEEERL---REQQEIELQKKRQEEETFLRVQEELQR 711
Query: 618 KMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQ--- 674
E+ E + + + + + E +EL+K+ LEE +A L+ Q
Sbjct: 712 LKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLRE 771
Query: 675 -----------------------ETVHEVALKDKEP---DTQDADEVKKALELQMESHRE 708
E + E L+ KE +D +E++KA E R
Sbjct: 772 KQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKR- 830
Query: 709 AHHRQLAR--------------LRDEINEKQKTIDELKDLNQKLQLELEK---------- 744
RQL + L+ E+ E+Q+ ++ LK + K LEK
Sbjct: 831 ---RQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTE 887
Query: 745 LQADYEKLKSEEHEKSTKLQELTFLYERH--------------------------EQSKQ 778
+ D+EK+K E+ K ++L +L + H Q ++
Sbjct: 888 VPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEK 947
Query: 779 DLKGLEETVARELQTLHNLRKL-----FVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFL 833
+++ EE +A+ + L+KL F ++ + +K + E E +KQ+ L
Sbjct: 948 EMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILES--REKQQREAL 1005
Query: 834 ENNLEQLTKVHKQLVRDNADLRCELPKLEKR---LRATAERVKALEGALKEAKEGAMKDK 890
E L +L + H L R ++ L E+ + ++ L + + L+ +L+ +E KD+
Sbjct: 1006 ERALARLERRHSALQR-HSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQ 1064
Query: 891 RRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASS 931
R + E+ ++K+ + ++ H + V P S+
Sbjct: 1065 ERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 246 bits (629), Expect = 6e-65
Identities = 259/963 (26%), Positives = 448/963 (46%), Gaps = 112/963 (11%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGK-------PYVFDRVFPPNTT--- 58
S+KV R RP N E + K I QG+ + +I K + FD + +T+
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64
Query: 59 -----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
Q +VY+ +++ GYN IFAYGQT +GK++TM GK + Q GIIP++
Sbjct: 65 PCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIPQLC 123
Query: 114 RDIFNHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTE 171
++F I + +E + + ++VSY EIY +++RDLL+ K NL V E P+V+ ++
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSK 183
Query: 172 RFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLS----GK 227
V+S +I D++D G R VA TNMNE SSRSH++F I Q+ + E LS K
Sbjct: 184 LAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSK 243
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-----YVPYRDS 282
+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +K ++PYRDS
Sbjct: 244 ISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDS 303
Query: 283 KMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQW 342
+T +L+++LGGN RT M SP+ N ET STL + RAK IK A +N + A
Sbjct: 304 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA--- 360
Query: 343 KKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDN 402
+ + KE + +L+ +L R + ++ +T + + L + +
Sbjct: 361 --------KLVRELKEEVTRLK-DLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSV 411
Query: 403 SSIVVRI----APEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVS 458
+SI RI EE + +E ++ +L++ +E ++++ I ++ +L + + +
Sbjct: 412 TSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIR 471
Query: 459 TRGDNEKV--QRELSHLQSEND----------AAKDEVKEVLQALEELAVNYDQKSQEVE 506
G V ++ HL + N+ KD + V QA E + ++
Sbjct: 472 EDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIK 531
Query: 507 EKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVG 566
E ++ + E S +++LE + V+G + + ++ +G +I+G
Sbjct: 532 E---EHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSG-------NRIIMG 581
Query: 567 NGEI-KLPVEISGAIEEEFTVARLYISKIKSE-VKSVVKRCRQLENLQVECHRKMEVTGR 624
+ + E E T + ++ SE V + LE ++ ++ME +
Sbjct: 582 KNHVFRFNHPEQARAEREKTPS----AETPSEPVDWTFAQRELLEKQGIDMKQEME---K 634
Query: 625 ELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEV-ALK 683
L ++L + + + L L+++ L+ DS D+ K +E+ + +L+
Sbjct: 635 RLQEMEILYKKEKEEADLL--------LEQQRLDADSDS-GDDSDKRSCEESWKLITSLR 685
Query: 684 DKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQK--TIDELKDLNQKLQLE 741
+K P ++ VKK RE R +++ K TI +LK + ++
Sbjct: 686 EKLPPSKLQTIVKKCGLPSSGKKREPIKMYQIPQRRRLSKDSKWVTISDLK-IQAVKEIC 744
Query: 742 LEKLQADYEKLKSE-EHEKSTKLQELTFLYERHEQSKQDLKGLEETVARELQTLHNLRKL 800
E D+ + E E K++EL +Y + + +++D VAR++ +
Sbjct: 745 YEVALNDFRHSRQEIEALAIVKMKELCAMYGKKDPNERD---SWRAVARDVWDTVGVGDE 801
Query: 801 FVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 860
++DV K S +++ K I LE+ L+++ K + + LR ++ K
Sbjct: 802 KIEDVMATGKGSTDVD--------DLKVHIDKLEDILQEVKKQNNMKDEEIKVLRNKMLK 853
Query: 861 LEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAK 920
+EK V L G+ ++ G+ K K V E ++ +G + ++AK
Sbjct: 854 MEK--------VLPLIGSQEQKSPGSHKAKEPVGAGVSSTSE-----NNVSKGDNGELAK 900
Query: 921 PVR 923
R
Sbjct: 901 EER 903
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 244 bits (622), Expect = 4e-64
Identities = 188/614 (30%), Positives = 306/614 (49%), Gaps = 67/614 (10%)
Query: 2 AETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKP----------YVFDR 51
++T ++KV+ R RPL++ E G + I V P + FD
Sbjct: 3 SKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDA 62
Query: 52 VFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPR 111
V+ ++ Q +Y ++ VL G+NGT+FAYGQT +GKT+TM+G +P+L G+IP
Sbjct: 63 VYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPN 122
Query: 112 IARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTK-TNLSVHEDKNRVPFVKGCT 170
IF HI S +N ++ ++ SY EIY ++IRDLL L + E+ ++K +
Sbjct: 123 AFEHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLS 181
Query: 171 ERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQK---LSGK 227
+ +EI V++ G R V T+MNE SSRSH+IF+I ++ ++ + GK
Sbjct: 182 SFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGK 241
Query: 228 LYLVDLAGSEKVSKTG------------------------AEGAVLDEAKNINKSLSALG 263
L LVDLAGSE+ +K G A G EA IN SLSALG
Sbjct: 242 LNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALG 301
Query: 264 NVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQR 323
NVI+ALA +++PYRDSK+TR+LQDSLGGN +T M P+S++ E+ STL F R
Sbjct: 302 NVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANR 361
Query: 324 AKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKL----EAELSRWRNGENVPET 379
AK IKN VN E + +++++E + KAQ E L + SR + + P
Sbjct: 362 AKNIKNKPRVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
Query: 380 ERLAGEEAALGAELCEETPVNDNSSIVVRIAPEE--RQKYEEEIRRLYKQLDDKDDEINQ 437
E + A + EE N+N+ + E + E ++ ++L+++ I
Sbjct: 421 ---YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQD 477
Query: 438 QSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEV----KEVLQALEE 493
L+ + KQ++L+++E ++ D + Q+ L ++ A + ++ + ++ E
Sbjct: 478 DRSLVSEEKQKLLEEKEKMLE---DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNE 534
Query: 494 LAVNYDQKSQEV------EEKSQQNQLLVDELSQKV-ATMLSLESELQRLQEVSGHQRKR 546
+ K QE+ E + QQ +L DE + ++ T SL+ E+ EV + K+
Sbjct: 535 QQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEV----EVKTKKLKK 590
Query: 547 IAEVLNGLMKDLSE 560
+ L + ++ +
Sbjct: 591 LYAKLQAVKAEIQD 604
Score = 38.9 bits (89), Expect = 0.025
Identities = 39/190 (20%), Positives = 88/190 (46%), Gaps = 34/190 (17%)
Query: 641 RSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALE 700
+++ Y+Q +K LEE ++ D+ + + ++ + L++KE +D ++A E
Sbjct: 455 KNMENYLQE---QKERLEEEKAAIQDDRSLVSEEK---QKLLEEKEKMLEDLRREQQATE 508
Query: 701 LQMESHREAHHRQLA---RLRDEINEKQKTID-----------ELKDLNQKLQL---ELE 743
L ++ + L + D NE+QK ++ +++ Q++ L E
Sbjct: 509 LLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETM 568
Query: 744 KLQADYEKLKSEEHEKSTKLQEL--------TFLYERHEQ---SKQDLKGLEETVARELQ 792
+L+ Y L+ E K+ KL++L + ++H++ +QDL+ + REL+
Sbjct: 569 ELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELK 628
Query: 793 TLHNLRKLFV 802
+ + + F+
Sbjct: 629 LKYLIIENFI 638
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 239 bits (611), Expect = 7e-63
Identities = 179/533 (33%), Positives = 270/533 (50%), Gaps = 43/533 (8%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKF-IPIFQGDDSVVIG-GKPYVFDRVFPPNTTQEQVYH 64
E ++V R RPL E+L G + + + G V +G + + F V + QE VY
Sbjct: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
Query: 65 ACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTM-----EGKLHDPQLMGIIPRIARDIFNH 119
AC +++ G+N T+FAYGQT SGKT+TM L D Q GI+PR + F
Sbjct: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQ--GIVPRAMAEAFKL 130
Query: 120 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNRVPFVKGCTERFVS 175
I DEN L+ + VSY E+Y ++ RDLL+V ++ + ED+ + G E V
Sbjct: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
Query: 176 SPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETE--------QKLSGK 227
+E+L +++ G + RH T++N SSRSH++F + ++Q Q L K
Sbjct: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTK--SYVPYRDSKMT 285
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + + S++PYRDSK+T
Sbjct: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
Query: 286 RILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKK 345
RIL+DSLGGN +T M C SPSS + ET +TL + RA+ I+N A+VN W+ +
Sbjct: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
Query: 346 YEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEA-ALGAELCEETPVNDNSS 404
E+ E+T + + +E G P + A LGAE D +
Sbjct: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACTDAAY 420
Query: 405 IVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQL------IEKLKQQMLDQEELLVS 458
++R E R++ L + E + S IE + DQ
Sbjct: 421 SLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSASGPDSGIESASVE--DQAAQGAG 478
Query: 459 TRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQ 511
R ++E Q+ L+ LQ++ ++E ++ L ALE+ Y +S + E+ ++
Sbjct: 479 GRKEDEGAQQLLT-LQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEE 530
Score = 47.4 bits (111), Expect = 7e-05
Identities = 101/507 (19%), Positives = 207/507 (40%), Gaps = 65/507 (12%)
Query: 319 MFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQ----KETIAKLEA-ELSRWRNG 373
+ G+ +T K ++N + + Q ++ E+E E+ +A+ + + +LE EL
Sbjct: 723 LIGELVRTGKAAQALNRQHS--QRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGER 780
Query: 374 ENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDD 433
+ E R + L E+ + + + + Q+ E ++ + +Q
Sbjct: 781 SRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQR 840
Query: 434 EINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVK-------- 485
+ ++++ +L+ +M ++ + +E+ Q+ L +++E AA +
Sbjct: 841 RLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILK-IKTEEIAAFQRKRRSGSNGSV 899
Query: 486 ---EVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLS----------LESE 532
E Q +EE DQ+ ++V ++ + + L +EL ++ A + LES+
Sbjct: 900 VSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESK 959
Query: 533 LQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIE------EEFTV 586
R + R++ L L K+LSE S + G + +I G I+ +
Sbjct: 960 RLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLRQEKDSLLK 1019
Query: 587 ARLYI-SKIK-------SEVKSVVKRCRQLENLQVECHRKME-VTGRE--LSSCQLLISQ 635
RL I K++ E +++ + +E L K E +T R+ L + L+SQ
Sbjct: 1020 QRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQ 1079
Query: 636 HEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEV 695
E + + Y+ S E R L Y D++ L+ ++ ++A + E ++ +
Sbjct: 1080 CEMNLMAKLSYLSSSE--TRALLCKY---FDKVVTLREEQHQQQIAFSELEMQLEEQQRL 1134
Query: 696 KKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADY-EKLKS 754
LE+ +E R RQL + K+ Q +QL L++ + E L
Sbjct: 1135 VYWLEVALERQRLEMDRQLTL-------------QQKEHEQNMQLLLQQSRDHLGEGLAD 1181
Query: 755 EEHEKSTKLQELTFLYERHEQSKQDLK 781
+ ++Q L R+ Q+LK
Sbjct: 1182 SRRQYEARIQALEKELGRYMWINQELK 1208
Score = 32.7 bits (73), Expect = 1.8
Identities = 46/217 (21%), Positives = 95/217 (43%), Gaps = 38/217 (17%)
Query: 712 RQLA---RLRDE-INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELT 767
R+LA R+++E I E +T + LN++ + +L+ + E++++E E +L+EL
Sbjct: 711 RELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLREL- 769
Query: 768 FLYERHEQSKQDLKGLEETVARELQTLHNLRK-LFVQDVTTRVKKSAEMEPEDSGGIHSQ 826
+G E A E L R+ + +V K + E + +Q
Sbjct: 770 -------------EGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQ 816
Query: 827 KQK-ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGAL--KEAK 883
+K + LE N++ + + QL ++RLR E+ + LE + ++ +
Sbjct: 817 SEKRLQELERNVQLMRQQQGQL--------------QRRLREETEQKRRLEAEMSKRQHR 862
Query: 884 EGAMKDKRRYQQEVDRIK--EAVRYKSSGKRGHSAQI 918
++ K QQ++ +IK E ++ + G + +
Sbjct: 863 VKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSV 899
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 238 bits (606), Expect = 3e-62
Identities = 169/484 (34%), Positives = 261/484 (53%), Gaps = 45/484 (9%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGK-------PYVFDRVFPPNTT--- 58
S+KV R RP N E + K I QG+ + +I K + FD + +T+
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPED 64
Query: 59 -----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
Q +VY+ +++ GYN IFAYGQT +GK++TM GK + Q GIIP++
Sbjct: 65 PCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIPQLC 123
Query: 114 RDIFNHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTE 171
++F I + +E + + ++VSY EIY +++RDLL+ K NL V E P+V+ ++
Sbjct: 124 EELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSK 183
Query: 172 RFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLS----GK 227
V+S +I D++D G R VA TNMNE SSRSH++F I Q+ + E LS K
Sbjct: 184 LAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSK 243
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-----YVPYRDS 282
+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +K ++PYRDS
Sbjct: 244 ISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDS 303
Query: 283 KMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQW 342
+T +L+++LGGN RT M SP+ N ET STL + RAK IK A +N + A
Sbjct: 304 VLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNA--- 360
Query: 343 KKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDN 402
+ + KE + +L+ +L R + ++ +T + + L + +
Sbjct: 361 --------KLVRELKEEVTRLK-DLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTSV 411
Query: 403 SSIVVRI----APEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVS 458
+SI RI EE + +E ++ +L++ +E ++++ I ++ +L E+ V+
Sbjct: 412 TSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALL--AEMGVA 469
Query: 459 TRGD 462
R D
Sbjct: 470 IRED 473
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 237 bits (605), Expect = 4e-62
Identities = 167/424 (39%), Positives = 237/424 (55%), Gaps = 40/424 (9%)
Query: 6 NECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGG------------KPYVFDRVF 53
++ +KV R RP+N+ E+ K + +G+ +V+ K + FD F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 54 ----PPNTT----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
NTT QE V+ I++ GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIARDIFNHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD ++ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ 222
P+V G ++ V+S E+I ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASV 333
+VPYRDS +T +L+D+LGGN +T+M SP++ N ET STL + RAK I N A V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAEL 393
N + A K + +E+ + +E +++ EA + E + E+E+L E E
Sbjct: 359 NEDPNA----KVIRELREEVEKLREQLSQAEA-MKAPELKEKLEESEKLIKELTVTWEEK 413
Query: 394 CEET 397
+T
Sbjct: 414 LRKT 417
Score = 37.4 bits (85), Expect = 0.074
Identities = 46/217 (21%), Positives = 100/217 (46%), Gaps = 28/217 (12%)
Query: 366 ELSRWRNGENVPETER--LAGEE-----AALGAELCEETPVNDN--------SSIVVRIA 410
+L +GE V + LAG E A G L E + +N + SS+ + A
Sbjct: 235 DLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAA 294
Query: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
+ + K+ + L + N Q+ +I + + EE L ST ++ +R +
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETL-STLRYADRAKRIV 353
Query: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQ----KSQEVEEKSQQNQLLVDELSQKVATM 526
+H D ++E+ + +E+L Q K+ E++EK ++++ L+ EL+
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELT------ 407
Query: 527 LSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSV 563
++ E +L++ +E++ +++++ + G+ ++S V
Sbjct: 408 VTWEEKLRKTEEIAQERQRQLESM--GISLEMSGIKV 442
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 237 bits (605), Expect = 4e-62
Identities = 167/424 (39%), Positives = 237/424 (55%), Gaps = 40/424 (9%)
Query: 6 NECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGG------------KPYVFDRVF 53
++ +KV R RP+N+ E+ K + +G+ +V+ K + FD F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 54 ----PPNTT----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
NTT QE V+ I++ GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIARDIFNHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD ++ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ 222
P+V G ++ V+S E+I ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASV 333
+VPYRDS +T +L+D+LGGN +T+M SP++ N ET STL + RAK I N A V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAEL 393
N + A K + +E+ + +E +++ EA + E + E+E+L E E
Sbjct: 359 NEDPNA----KVIRELREEVEKLREQLSQAEA-MKAPELKEKLEESEKLIKELTVTWEEK 413
Query: 394 CEET 397
+T
Sbjct: 414 LRKT 417
Score = 37.4 bits (85), Expect = 0.074
Identities = 46/217 (21%), Positives = 100/217 (46%), Gaps = 28/217 (12%)
Query: 366 ELSRWRNGENVPETER--LAGEE-----AALGAELCEETPVNDN--------SSIVVRIA 410
+L +GE V + LAG E A G L E + +N + SS+ + A
Sbjct: 235 DLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAA 294
Query: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
+ + K+ + L + N Q+ +I + + EE L ST ++ +R +
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETL-STLRYADRAKRIV 353
Query: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQ----KSQEVEEKSQQNQLLVDELSQKVATM 526
+H D ++E+ + +E+L Q K+ E++EK ++++ L+ EL+
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELT------ 407
Query: 527 LSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSV 563
++ E +L++ +E++ +++++ + G+ ++S V
Sbjct: 408 VTWEEKLRKTEEIAQERQRQLESM--GISLEMSGIKV 442
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 237 bits (605), Expect = 4e-62
Identities = 167/424 (39%), Positives = 237/424 (55%), Gaps = 40/424 (9%)
Query: 6 NECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGG------------KPYVFDRVF 53
++ +KV R RP+N+ E+ K + +G+ +V+ K + FD F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 54 ----PPNTT----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
NTT QE V+ I++ GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIARDIFNHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD ++ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ 222
P+V G ++ V+S E+I ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASV 333
+VPYRDS +T +L+D+LGGN +T+M SP++ N ET STL + RAK I N A V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAEL 393
N + A K + +E+ + +E +++ EA + E + E+E+L E E
Sbjct: 359 NEDPNA----KVIRELREEVEKLREQLSQAEA-MKAPELKEKLEESEKLIKELTVTWEEK 413
Query: 394 CEET 397
+T
Sbjct: 414 LRKT 417
Score = 37.4 bits (85), Expect = 0.074
Identities = 46/217 (21%), Positives = 100/217 (46%), Gaps = 28/217 (12%)
Query: 366 ELSRWRNGENVPETER--LAGEE-----AALGAELCEETPVNDN--------SSIVVRIA 410
+L +GE V + LAG E A G L E + +N + SS+ + A
Sbjct: 235 DLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAA 294
Query: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
+ + K+ + L + N Q+ +I + + EE L ST ++ +R +
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETL-STLRYADRAKRIV 353
Query: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQ----KSQEVEEKSQQNQLLVDELSQKVATM 526
+H D ++E+ + +E+L Q K+ E++EK ++++ L+ EL+
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELT------ 407
Query: 527 LSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSV 563
++ E +L++ +E++ +++++ + G+ ++S V
Sbjct: 408 VTWEEKLRKTEEIAQERQRQLESM--GISLEMSGIKV 442
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 237 bits (605), Expect = 4e-62
Identities = 167/424 (39%), Positives = 237/424 (55%), Gaps = 40/424 (9%)
Query: 6 NECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGG------------KPYVFDRVF 53
++ +KV R RP+N+ E+ K + +G+ +V+ K + FD F
Sbjct: 2 SDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYCF 61
Query: 54 ----PPNTT----QEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
NTT QE V+ I++ GYN IFAYGQT SGK+ +M G H QL
Sbjct: 62 WSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG--HAEQL 119
Query: 106 MGIIPRIARDIFNHI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNR 162
G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD ++ +L V E K
Sbjct: 120 -GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVL 178
Query: 163 VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ 222
P+V G ++ V+S E+I ++ EG +R VA TNMNE SSRSH++F I I Q + +
Sbjct: 179 GPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQS 238
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GT 273
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+ G
Sbjct: 239 GNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKGK 298
Query: 274 KSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASV 333
+VPYRDS +T +L+D+LGGN +T+M SP++ N ET STL + RAK I N A V
Sbjct: 299 SKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAVV 358
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAEL 393
N + A K + +E+ + +E +++ EA + E + E+E+L E E
Sbjct: 359 NEDPNA----KVIRELREEVEKLREQLSQAEA-MKAPELKEKLEESEKLIKELTVTWEEK 413
Query: 394 CEET 397
+T
Sbjct: 414 LRKT 417
Score = 37.4 bits (85), Expect = 0.074
Identities = 46/217 (21%), Positives = 100/217 (46%), Gaps = 28/217 (12%)
Query: 366 ELSRWRNGENVPETER--LAGEE-----AALGAELCEETPVNDN--------SSIVVRIA 410
+L +GE V + LAG E A G L E + +N + SS+ + A
Sbjct: 235 DLQSGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAA 294
Query: 411 PEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQREL 470
+ + K+ + L + N Q+ +I + + EE L ST ++ +R +
Sbjct: 295 GKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETL-STLRYADRAKRIV 353
Query: 471 SHLQSENDAAKDEVKEVLQALEELAVNYDQ----KSQEVEEKSQQNQLLVDELSQKVATM 526
+H D ++E+ + +E+L Q K+ E++EK ++++ L+ EL+
Sbjct: 354 NHAVVNEDPNAKVIRELREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKELT------ 407
Query: 527 LSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSV 563
++ E +L++ +E++ +++++ + G+ ++S V
Sbjct: 408 VTWEEKLRKTEEIAQERQRQLESM--GISLEMSGIKV 442
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 234 bits (598), Expect = 2e-61
Identities = 165/489 (33%), Positives = 255/489 (52%), Gaps = 49/489 (10%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKP-------YVFDRVFPPNTTQEQ 61
S+KV R RP N E+ R K I G + ++ K + FD + +T+ E
Sbjct: 5 SVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHTSPED 64
Query: 62 VYHACAMQIVKDV--------LAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
+ +A Q+ +D+ GYN IFAYGQT +GK++TM GK Q GIIP++
Sbjct: 65 INYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQ-QGIIPQLC 123
Query: 114 RDIFNHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTE 171
D+F+ I + ++N+ + ++VSY EIY +++RDLL+ K NL V E P+V+ ++
Sbjct: 124 EDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSK 183
Query: 172 RFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLS----GK 227
V+S +I D++D G R VA TNMNE SSRSH++F I Q+ + E ++ K
Sbjct: 184 LAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSK 243
Query: 228 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-----------Y 276
+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +
Sbjct: 244 ISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTDF 303
Query: 277 VPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLE 336
+PYRDS +T +L+++LGGN RT M SP+ N ET STL + RAK I+ A +N
Sbjct: 304 IPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVIN-- 361
Query: 337 LTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAG--EEAALGAELC 394
+ + + K+ + +L L G+ T L G ++L A
Sbjct: 362 ---------EDPNNKLIRELKDEVTRLRDLLYAQGLGDITDMTNALVGMSPSSSLSALSS 412
Query: 395 EETPVND-NSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQE 453
V+ + I+ EE + +E ++ +L++ +E ++++ I ++ +L
Sbjct: 413 RAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALL--A 470
Query: 454 ELLVSTRGD 462
E+ V+ R D
Sbjct: 471 EMGVAMRED 479
>gi|157502184 kinesin family member 6 [Homo sapiens]
Length = 814
Score = 224 bits (570), Expect = 4e-58
Identities = 198/690 (28%), Positives = 329/690 (47%), Gaps = 86/690 (12%)
Query: 47 YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLM 106
+ F R+F + QE V+ A + VLAGYNGTIFAYGQT SGKT T+ G
Sbjct: 58 FKFQRIFDQDANQETVFENIAKPVAGSVLAGYNGTIFAYGQTGSGKTFTITGGAERYSDR 117
Query: 107 GIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKT--------NLSVHE 158
GIIPR IF + D + + +SY EIY + DLLD +++ E
Sbjct: 118 GIIPRTLSYIFEQLQK-DSSKIYTTHISYLEIYNECGYDLLDPRHEASSLEDLPKVTILE 176
Query: 159 DKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENM 218
D ++ +K T ++ EE L+++ G +NR +A T MN+ S+RSH IF I++ +
Sbjct: 177 DPDQNIHLKNLTLHQATTEEEALNLLFLGDTNRMIAETPMNQASTRSHCIFTIHLSSKEP 236
Query: 219 ETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVP 278
+ KL+LVDLAGSE+V+KTG G +L EAK IN SL L VI AL+E +S++P
Sbjct: 237 GSATVRHAKLHLVDLAGSERVAKTGVGGHLLTEAKYINLSLHYLEQVIIALSEKHRSHIP 296
Query: 279 YRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELT 338
YR+S MT +L+DSLGGNC TTM S N E+ ST F QR IKN A +N E+
Sbjct: 297 YRNSMMTSVLRDSLGGNCMTTMIATLSLEKRNLDESISTCRFAQRVALIKNEAVLNEEIN 356
Query: 339 AEQWKKKYEKEKEKTK-------AQKETIAKLEAELSRWRNGENVPETERLAGEEAALGA 391
K+ +KE ++ K ++ T A EAEL + ++ + +GA
Sbjct: 357 PRLVIKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGA 416
Query: 392 E-------------LCEETPVNDNSSIVVRIAPEERQK--YEEEIRRLYKQLDDKDDEIN 436
+ L + + +N+++ ++ Q+ EEE R+L L +D+EIN
Sbjct: 417 DMRKVHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQRDNEIN 476
Query: 437 QQSQLIEKLKQQM--------LDQEELLVSTR-----GDNEKVQRELSHLQSENDAAKD- 482
+++K K++ +D+ E S G+ E+ QR L S A+D
Sbjct: 477 ILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQR--MRLSSAPSQAQDF 534
Query: 483 --------EVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDE----LSQKVATMLSLE 530
+ + + EE+++ Q++ E+ ++ + + +D+ L Q+ + +L
Sbjct: 535 SILGKRSSLLHKKIGMREEMSLGC-QEAFEIFKRDHADSVTIDDNKQILKQRFSEAKALG 593
Query: 531 SELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLY 590
+ + GH ++ I + + + + V +G E + V + +EE
Sbjct: 594 ESINEARSKIGHLKEEITQ------RHIQQ--VALGISE-NMAVPLMPDQQEE------- 637
Query: 591 ISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSV 650
K++S+++ +R + + +++ E+ QLL+ + + K++ E +
Sbjct: 638 --KLRSQLEEEKRRYKTM-------FTRLKALKVEIEHLQLLMDKAKVKLQKEFEVWWAE 688
Query: 651 ELKKRHLEE-SYDSLSDELAKLQAQETVHE 679
E + + +SL LQ ++ HE
Sbjct: 689 EATNLQVNSPAVNSLDHTKPFLQTSDSQHE 718
Score = 40.4 bits (93), Expect = 0.009
Identities = 74/356 (20%), Positives = 147/356 (41%), Gaps = 64/356 (17%)
Query: 421 IRRLYKQLDDKDDEINQQS--QLIEKLKQ-QMLDQEELLVSTRGDNEKVQR-ELSHLQSE 476
I+RL K++ + DE+ + Q E L + ++L E+L+ S D + R E+ +
Sbjct: 361 IKRLQKEIQELKDELAMVTGEQRTEALTEAELLQLEKLITSFLEDQDSDSRLEVGADMRK 420
Query: 477 NDAAKDEVKEVL---QALEELAVNYDQKSQEVEE--KSQQNQLLVDELSQKVATMLSLES 531
+K++L + LE V+ + K Q+ +E K ++ + L D L Q+ ++
Sbjct: 421 VHHCFHHLKKLLNDKKILENNTVSSESKDQDCQEPLKEEEYRKLRDILKQR-------DN 473
Query: 532 ELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVI------VGNGEIKLPVEISGAIEE--E 583
E+ L + ++K+ E L+ D EF +GN E + +S A + +
Sbjct: 474 EINILVNMLKKEKKKAQEALHLAGMDRREFRQSQSPPFRLGNPEEGQRMRLSSAPSQAQD 533
Query: 584 FTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRE------LSSCQLLISQHE 637
F++ S + K+ E + + C E+ R+ + + ++ Q
Sbjct: 534 FSILGKRSSLLH-------KKIGMREEMSLGCQEAFEIFKRDHADSVTIDDNKQILKQRF 586
Query: 638 AKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKK 697
++ ++L E + K HL+E Q + +VAL E
Sbjct: 587 SEAKALGESINEARSKIGHLKEEI-----------TQRHIQQVALGISE---------NM 626
Query: 698 ALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLK 753
A+ L + E +LR ++ E+++ + + L++E+E LQ +K K
Sbjct: 627 AVPLMPDQQEE-------KLRSQLEEEKRRYKTMFTRLKALKVEIEHLQLLMDKAK 675
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 223 bits (569), Expect = 6e-58
Identities = 169/524 (32%), Positives = 265/524 (50%), Gaps = 76/524 (14%)
Query: 9 SIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKP-------YVFDRVF-------- 53
S+KV R RP N E + K + QG+ + +I K + FD +
Sbjct: 5 SVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHTSTED 64
Query: 54 PPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
P +Q+QVY +++ GYN IFAYGQT +GK++TM G+ +P GI+P++
Sbjct: 65 PQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGR-QEPGQQGIVPQLC 123
Query: 114 RDIFNHIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-TKTNLSVHEDKNRVPFVKGCTE 171
D+F+ + + L + ++VSY EIY +++RDLL+ ++ +L V E P+V+ ++
Sbjct: 124 EDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQDLSK 183
Query: 172 RFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMET-----EQKLSG 226
V+S +I D++D G R VA TNMNE SSRSH++F I Q + +K+S
Sbjct: 184 LAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSEKVS- 242
Query: 227 KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-----GTKSYVPYRD 281
K+ LVDLAGSE+ +GA G L E NINKSL+ LG VISALA+ ++PYRD
Sbjct: 243 KISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIPYRD 302
Query: 282 SKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQ 341
S +T +L+++LGGN RT M SP+ N ET STL + R K I+ A +N + A
Sbjct: 303 SVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPNA-- 360
Query: 342 WKKKYEKEKEKTKAQKETIAKLEAELSRWR-----NGENVPETERLAGEE----AALGAE 392
I +L+ E++R R G + E L EE AL A
Sbjct: 361 ----------------RLIRELQEEVARLRELLMAQGLSASALEGLKTEEGSVRGALPAV 404
Query: 393 LCEETPVNDNS--------------SIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQ 438
PV+ +S + +I PEE + +E ++ +L++ +E ++
Sbjct: 405 SSPPAPVSPSSPTTHNGELEPSFSPNTESQIGPEEAMERLQETEKIIAELNETWEEKLRK 464
Query: 439 SQLIEKLKQQMLDQEELLVSTRGDNEKV----QRELSHLQSEND 478
++ + ++ +L E+ V+ R D V ++ HL + N+
Sbjct: 465 TEALRMEREALL--AEMGVAVREDGGTVGVFSPKKTPHLVNLNE 506
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 221 bits (563), Expect = 3e-57
Identities = 156/424 (36%), Positives = 222/424 (52%), Gaps = 41/424 (9%)
Query: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVV-----------IGGKPYVF------ 49
+ +KV R RP+N+ E K + + ++ G+P VF
Sbjct: 3 DSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCF 62
Query: 50 ----DRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQL 105
+ V Q+ V+ I+++ GYN IFAYGQT SGK++TM G P
Sbjct: 63 WSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP-- 120
Query: 106 MGIIPRIARDIFNHIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDV--TKTNLSVHEDKNR 162
G+IPR+ +F + E F ++VSY EIY +K+RDLLD ++ L V E
Sbjct: 121 -GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVL 179
Query: 163 VPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQ 222
P+V G ++ V+S ++I ++ EG +R VA TNMNE SSRSH++F I + + +
Sbjct: 180 GPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKS 239
Query: 223 KLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGT----- 273
SG KL LVDLAGSE+ +KTGA G L E NINKSL+ LG VISALA+ +
Sbjct: 240 GTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGKNK 299
Query: 274 KSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASV 333
+VPYRDS +T +L+DSLGGN +T M SP++ N ET STL + RAK I N A V
Sbjct: 300 NKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHAVV 359
Query: 334 NLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAEL 393
N + A + +E+ + +E + K EA S + + E+E+L E E
Sbjct: 360 NEDPNA----RIIRDLREEVEKLREQLTKAEAMKSP-ELKDRLEESEKLIQEMTVTWEEK 414
Query: 394 CEET 397
+T
Sbjct: 415 LRKT 418
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 218 bits (556), Expect = 2e-56
Identities = 185/577 (32%), Positives = 281/577 (48%), Gaps = 85/577 (14%)
Query: 10 IKVLCRFRPLNQAEILRG--------DKFIPIF---QGDDSVVIGGKP------------ 46
+KV+ R RP N E G DK I +F Q + S G K
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 47 --YVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQ 104
+VFD VF +TQ +V+ I++ L GYN T+ AYG T +GKTHTM G +P
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEPG 131
Query: 105 LMGIIPRIARDIFNHIYS-MDENLEFHI---KVSYFEIYLDKIRDLLDVTKTNLSVHEDK 160
+M + H+Y MDE E I VSY E+Y ++IRDLL V L+V ED
Sbjct: 132 VMYLT-------MLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLL-VNSGPLAVREDT 183
Query: 161 NRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMET 220
+ V G T S EEIL ++D G NR T+MN SSRSH++F I ++Q++
Sbjct: 184 QKGVVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTA 243
Query: 221 EQKLS---GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKS-- 275
+ K+ L+DLAGSE+ S +GA+G E NIN+SL ALGNVI+ALA+ +
Sbjct: 244 SINQNVRIAKMSLIDLAGSERASTSGAKGTRFVEGTNINRSLLALGNVINALADSKRKNQ 303
Query: 276 YVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNL 335
++PYR+SK+TR+L+DSLGGNC+T M SPSS +T +TL + RAK IK++ N+
Sbjct: 304 HIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDTYNTLKYANRAKDIKSSLKSNV 363
Query: 336 ELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCE 395
L +Y K + KA+ I L+ +L + E+ A
Sbjct: 364 -LNVNNHITQYVKICNEQKAE---ILLLKEKLKAYE-------------EQKAF------ 400
Query: 396 ETPVNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEEL 455
T ND + +++ ++K E + + L +EI Q E LK +ML +E
Sbjct: 401 -TNENDQAKLMI---SNPQEKEIERFQEILNCLFQNREEIRQ-----EYLKLEMLLKENE 451
Query: 456 LVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLL 515
L S ++ H Q E ++D+V++ + + +E++ ++
Sbjct: 452 LKS-------FYQQQCHKQIEMMCSEDKVEKATGKRDHRLAMLKTRRSYLEKRREEE--- 501
Query: 516 VDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLN 552
+ + + + +E E+ L + +GH K + + L+
Sbjct: 502 LKQFDENTNWLHRVEKEMGLLSQ-NGHIPKELKKDLH 537
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 218 bits (554), Expect = 3e-56
Identities = 168/537 (31%), Positives = 265/537 (49%), Gaps = 57/537 (10%)
Query: 10 IKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGG----------------KPYVFDRVF 53
+ V R RP++ AE+ G I + VV+ K Y+FD F
Sbjct: 12 LMVALRVRPISVAELEEGATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFDVAF 71
Query: 54 PPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIA 113
TQE VY A +++ V++GYN T+FAYG T GKT+TM G +P GI +
Sbjct: 72 DFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP---GIYVQTL 128
Query: 114 RDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERF 173
D+F I ++E+ + +SY EIY + IRDLL+ + L + ED V V G TE
Sbjct: 129 NDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLGYLELREDSKGVIQVAGITEVS 188
Query: 174 VSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENME---TEQKLSGKLYL 230
+ +EI+ ++ +G R T N+ SSRSH++ + ++Q + ++ G+L++
Sbjct: 189 TINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQGRLFM 248
Query: 231 VDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE-GTKSYVPYRDSKMTRILQ 289
+DLAGSE+ S+T G + E +IN+SL ALGN I+AL++ G+ Y+ YRDSK+TR+L+
Sbjct: 249 IDLAGSERASQTQNRGQRMKEGAHINRSLLALGNCINALSDKGSNKYINYRDSKLTRLLK 308
Query: 290 DSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNL--------ELTAEQ 341
DSLGGN RT M SP+S E+++TL + RAK IK NL + T+
Sbjct: 309 DSLGGNSRTVMIAHISPASSAFEESRNTLTYAGRAKNIKTRVKQNLLNVSYHIAQYTSII 368
Query: 342 WKKKYEKEKEKTKAQKET---IAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETP 398
+ E ++ K K ++T A+ + R+ + + GE+A +G +L E+
Sbjct: 369 ADLRGEIQRLKRKIDEQTGRGQARGRQDRGDIRHIQAEVQLHSGQGEKAGMG-QLREQLA 427
Query: 399 VNDNSSIVVRIAPEERQKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVS 458
+ VR R+ E E R + Q+D + EK ++ + +EE
Sbjct: 428 SAFQEQMDVR-----RRLLELENRAMEVQIDTSRHLLTIAGWKHEKSRRALKWREEQRKE 482
Query: 459 --TRGDNEKVQRELSHLQSENDAAKD-----EVKEVLQALEELAVNYDQKSQEVEEK 508
+ D+EK ++D D E EV A E +A D++ Q ++K
Sbjct: 483 CYAKDDSEK----------DSDTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQK 529
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,909,404
Number of Sequences: 37866
Number of extensions: 1630172
Number of successful extensions: 20580
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 460
Number of HSP's successfully gapped in prelim test: 1141
Number of HSP's that attempted gapping in prelim test: 8055
Number of HSP's gapped (non-prelim): 6149
length of query: 1032
length of database: 18,247,518
effective HSP length: 112
effective length of query: 920
effective length of database: 14,006,526
effective search space: 12886003920
effective search space used: 12886003920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.