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Search of human proteins with 45269141
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45269141 multimerin 1 [Homo sapiens]
(1228 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45269141 multimerin 1 [Homo sapiens] 2429 0.0
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 93 1e-18
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 92 2e-18
gi|221316695 multimerin 2 precursor [Homo sapiens] 86 3e-16
gi|60498978 elastin microfibril interfacer 2 [Homo sapiens] 84 1e-15
gi|5901944 elastin microfibril interfacer 1 [Homo sapiens] 82 3e-15
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 77 1e-13
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 77 1e-13
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 76 2e-13
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 72 3e-12
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 72 3e-12
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens] 72 3e-12
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 72 3e-12
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 72 3e-12
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 72 3e-12
gi|71061468 centromere protein E [Homo sapiens] 71 6e-12
gi|50511941 EMI domain containing 1 [Homo sapiens] 67 8e-11
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 65 4e-10
gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens] 64 1e-09
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 62 3e-09
gi|55770834 centromere protein F [Homo sapiens] 60 1e-08
gi|157785668 coiled-coil domain containing 39 [Homo sapiens] 60 1e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 60 2e-08
gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens] 60 2e-08
gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens] 60 2e-08
gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens] 60 2e-08
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 59 2e-08
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 59 3e-08
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 59 3e-08
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 59 3e-08
>gi|45269141 multimerin 1 [Homo sapiens]
Length = 1228
Score = 2429 bits (6295), Expect = 0.0
Identities = 1228/1228 (100%), Positives = 1228/1228 (100%)
Query: 1 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV 60
MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV
Sbjct: 1 MKGARLFVLLSSLWSGGIGLNNSKHSWTIPEDGNSQKTMPSASVPPNKIQSLQILPTTRV 60
Query: 61 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN 120
MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN
Sbjct: 61 MSAEIATTPEARTSEDSLLKSTLPPSETSAPAEGVRNQTLTSTEKAEGVVKLQNLTLPTN 120
Query: 121 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR 180
ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR
Sbjct: 121 ASIKFNPGAESVVLSNSTLKFLQSFARKSNEQATSLNTVGGTGGIGGVGGTGGVGNRAPR 180
Query: 181 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW 240
ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW
Sbjct: 181 ETYLSRGDSSSSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGW 240
Query: 241 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT 300
TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT
Sbjct: 241 TGGSCPQRSQKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHT 300
Query: 301 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE 360
AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE
Sbjct: 301 AVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLE 360
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 420
GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL
Sbjct: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 420
Query: 421 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE 480
ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE
Sbjct: 421 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKE 480
Query: 481 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN 540
LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN
Sbjct: 481 LEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSN 540
Query: 541 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR 600
NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR
Sbjct: 541 NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR 600
Query: 601 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 660
NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR
Sbjct: 601 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 660
Query: 661 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 720
QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY
Sbjct: 661 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 720
Query: 721 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH 780
ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH
Sbjct: 721 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFH 780
Query: 781 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN 840
RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN
Sbjct: 781 RLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQN 840
Query: 841 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN 900
MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN
Sbjct: 841 MSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLN 900
Query: 901 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ 960
SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ
Sbjct: 901 SRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQ 960
Query: 961 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN 1020
KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN
Sbjct: 961 KGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVN 1020
Query: 1021 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL 1080
LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL
Sbjct: 1021 LTTVLIGRTQRNTDNIIYPEEYSSCSRHPCQNGGTCINGRTSFTCACRHPFTGDNCTIKL 1080
Query: 1081 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP 1140
VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP
Sbjct: 1081 VEENALAPDFSKGSYRYAPMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIP 1140
Query: 1141 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE 1200
YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE
Sbjct: 1141 YLGVYVFKYTIESFSAHISGFLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQE 1200
Query: 1201 VWLRLAKGTIPAKFPPVTTFSGYLLYRT 1228
VWLRLAKGTIPAKFPPVTTFSGYLLYRT
Sbjct: 1201 VWLRLAKGTIPAKFPPVTTFSGYLLYRT 1228
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 93.2 bits (230), Expect = 1e-18
Identities = 159/701 (22%), Positives = 296/701 (42%), Gaps = 101/701 (14%)
Query: 319 EVMQKMTDQVNYQAMKLT---LLQKKIDNISLT--VNDVRNTYSSLEGKVSE--DKSREF 371
E+ + + ++ +LT LL+ +++N SLT V ++R T S+EG S+ +E
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Query: 372 QSLLKGLKSKSINVLIRDIVREQFKI-----FQNDMQETVAQLFKTVSSLSEDLESTRQI 426
Q L SK + +L +IV+E+ + D+ + AQL KT+ +L E+ E +I
Sbjct: 501 QRL-----SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKI 555
Query: 427 IQKVNE------------SVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTC 474
+++ NE S +S A+ K + +EN+ I E + + + E
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDI-EKENKILHESIKETSSKLSKIEFEK---- 610
Query: 475 EKPIKELEVKQTHLEGALEQEHSRSILYYES--LNKTLSKLKEVHEQLLSTEQVS----- 527
+ KELE + E A E E+ L E+ L K ++ LK E++ + EQ +
Sbjct: 611 RQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER 670
Query: 528 -DQKNAPAAESVSNNVTEYMSTLHEN--IKKQSLMMLQMFEDLHIQESKINNLTV---SL 581
++K +S N + S EN + +++L + + E L K+ L + L
Sbjct: 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL 730
Query: 582 EMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLND 641
E EKE L+ E L K +L+ + + L + NQ L + L + K+ ++ +L D
Sbjct: 731 ESEKEQLKKGLE--LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Query: 642 LTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNL 701
L + + LQ LE+ K + K+ ++L + L K+L K +
Sbjct: 789 LEMENQTLQKNLEE--------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Query: 702 LRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEI 761
LR + + +D LE N + + NKT ++ I +++ + L K+N E+
Sbjct: 841 LRQQAEIKDTTLEE--NNVKIGNLEKENKT---LSKEIGIYKESCVRLKELE--KENKEL 893
Query: 762 HHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQ-VAKTLAGIPRDEKLNQSNF 820
+ T D++T++T Q + ND ++ L+ + + DE+ +
Sbjct: 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSR 953
Query: 821 QKMYQMFNETT--SQVRKYQQNMSHLEEKLLLTTK-----------ISKNFET--RLQDI 865
K+ + E+T + ++ ++ LE +L +T + KN+E + QD
Sbjct: 954 YKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDE 1013
Query: 866 ESKV----------------TQTLIPYYISVKKGSVVTNERDQALQL--QVLNSRFKALE 907
E V +Q + VK + + LQ Q L ++ K LE
Sbjct: 1014 ERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLE 1073
Query: 908 AKSIHLSINFFSLNK---TLHEVLTMCHNASTSVSELNATI 945
++ +L +L + +L E T + + N+T+
Sbjct: 1074 TQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Score = 56.2 bits (134), Expect = 2e-07
Identities = 106/528 (20%), Positives = 215/528 (40%), Gaps = 74/528 (14%)
Query: 401 DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELR 460
++ + A++ + L E E Q++ + + + Q QEN L+D R
Sbjct: 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQ-----QENMNLLSDARSAR 306
Query: 461 NHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQL 520
+ R E+ EK ++ V + E + +E I +Y++ + +LKE ++ L
Sbjct: 307 MY----RDELDALREKAVR---VDKLESEVSRYKERLHDIEFYKA---RVEELKEDNQVL 356
Query: 521 LSTE-QVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTV 579
L T+ + DQ A S LHE ++K++L + D+
Sbjct: 357 LETKTMLEDQLEGTRARS---------DKLHE-LEKENLQLKAKLHDM------------ 394
Query: 580 SLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHV---LNQTLAEVLFPMDNKMDKMS 636
EME++ R + E+++ + Q + +E+LH+ L Q ++ + +
Sbjct: 395 --EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQ-ISRTSELSEAPQKSLG 451
Query: 637 EQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELT 696
++N+LT L L + SL T T E+ + + +E S + + + L+
Sbjct: 452 HEVNELTSSR--LLKLEMENQSL--TKTVEELRTTV---DSVEGNASKILKMEKENQRLS 504
Query: 697 KRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIK 756
K+ +L NE+ +L+ N L+K D +++ L++T+ T++
Sbjct: 505 KKVEILENEIVQEKQSLQNCQN---------LSK---------DLMKEKAQLEKTIETLR 546
Query: 757 DNSEIHHKCTSDMETIL--TFIPQFHRLNDSIQTLVNDNQRYNFVL--QVAKTLAGIPRD 812
+NSE K L T R S + V D ++ N +L + +T + + +
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 813 EKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQT 872
E + +K + + E + + + + HLE++ L K N + + IE+ +
Sbjct: 607 E-FEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
Query: 873 LIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSL 920
+ K + + ++ QL+ L L+ +++ L N SL
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Score = 45.4 bits (106), Expect = 3e-04
Identities = 110/535 (20%), Positives = 201/535 (37%), Gaps = 119/535 (22%)
Query: 325 TDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSRE--FQSLLKGLKSKS 382
T Q+N KLT +++ I L N L + S D SR +S L+ KS
Sbjct: 918 TQQMNNDLEKLT---HELEKIGL------NKERLLHDEQSTDDSRYKLLESKLESTLKKS 968
Query: 383 INVLIRDIVREQFKIFQN-DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQ 441
+ + I + ++ ++ + + + Q KTV E L+ + + V S
Sbjct: 969 LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDN 1028
Query: 442 KFVLVQENRPTLTDIVELRNHIVNV-RQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSI 500
K+ +E++ T +++++++ ++ V R TL EK + ++KQ +
Sbjct: 1029 KWE--RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN---------- 1076
Query: 501 LYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMM 560
N +++ + Q +S ++ + A+ N T + QS +
Sbjct: 1077 ------NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST---------LNSQSTSL 1121
Query: 561 LQMFEDLHIQESKINNLTVSLEMEKESLR---------------------GECEDMLSKC 599
+ L IQ+S + N S+ E+E L+ E E ++SK
Sbjct: 1122 MNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK- 1180
Query: 600 RNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASL 659
LK +NL V ++ L + N++ K QL DL +++ EQ L
Sbjct: 1181 ----HGTLKSAHKNLEVEHRDLED----RYNQLLKQKGQLEDLEKMLKV-----EQEKML 1227
Query: 660 RQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALER-RIN 718
+ +E + + + L + LN +L K +L+ + + L ++
Sbjct: 1228 LENKNHE------TVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLE 1281
Query: 719 EYALEME--------DGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDME 770
+ LE E L+ T T +NN E LS +K N E ++
Sbjct: 1282 QTRLEAEFSKLKEQYQQLDITSTKLNNQC----------ELLSQLKGNLEEENR------ 1325
Query: 771 TILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRD---EKLNQSNFQK 822
L D IQTL+ N+ +K L + + +KLN+ QK
Sbjct: 1326 ----------HLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQK 1370
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 92.4 bits (228), Expect = 2e-18
Identities = 157/700 (22%), Positives = 294/700 (42%), Gaps = 100/700 (14%)
Query: 319 EVMQKMTDQVNYQAMKLT---LLQKKIDNISLT--VNDVRNTYSSLEGKVSE--DKSREF 371
E+ + + ++ +LT LL+ +++N SLT V ++R T S+EG S+ +E
Sbjct: 441 ELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKEN 500
Query: 372 QSLLKGLKSKSINVLIRDIVREQFKI-----FQNDMQETVAQLFKTVSSLSEDLESTRQI 426
Q L SK + +L +IV+E+ + D+ + AQL KT+ +L E+ E +I
Sbjct: 501 QRL-----SKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKI 555
Query: 427 IQKVNE------------SVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTC 474
+++ NE S +S A+ K + +EN+ I E + + + E
Sbjct: 556 LEQENEHLNQTVSSLRQRSQISAEARVKDI-EKENKILHESIKETSSKLSKIEFEK---- 610
Query: 475 EKPIKELEVKQTHLEGALEQEHSRSILYYES--LNKTLSKLKEVHEQLLSTEQVS----- 527
+ KELE + E A E E+ L E+ L K ++ LK E++ + EQ +
Sbjct: 611 RQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELER 670
Query: 528 -DQKNAPAAESVSNNVTEYMSTLHEN--IKKQSLMMLQMFEDLHIQESKINNLTV---SL 581
++K +S N + S EN + +++L + + E L K+ L + L
Sbjct: 671 ENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKEL 730
Query: 582 EMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLND 641
E EKE L+ E L K +L+ + + L + NQ L + L + K+ ++ +L D
Sbjct: 731 ESEKEQLKKGLE--LLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQD 788
Query: 642 LTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNL 701
L + + LQ LE+ K + K+ ++L + L K+L K +
Sbjct: 789 LEMENQTLQKNLEE--------LKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKR 840
Query: 702 LRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEI 761
LR + + +D LE N + + NKT ++ I +++ + L K+N E+
Sbjct: 841 LRQQAEIKDTTLEE--NNVKIGNLEKENKT---LSKEIGIYKESCVRLKELE--KENKEL 893
Query: 762 HHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQ-VAKTLAGIPRDEKLNQSNF 820
+ T D++T++T Q + ND ++ L+ + + DE+ +
Sbjct: 894 VKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRY 953
Query: 821 QKMYQMFNETTSQ-VRKYQQNMSHLEEKLLLTTK-----------ISKNFET--RLQDIE 866
+ + T + + ++ ++ LE +L +T + KN+E + QD E
Sbjct: 954 KLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEE 1013
Query: 867 SKV----------------TQTLIPYYISVKKGSVVTNERDQALQL--QVLNSRFKALEA 908
V +Q + VK + + LQ Q L ++ K LE
Sbjct: 1014 RMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLET 1073
Query: 909 KSIHLSINFFSLNK---TLHEVLTMCHNASTSVSELNATI 945
++ +L +L + +L E T + + N+T+
Sbjct: 1074 QNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1113
Score = 56.2 bits (134), Expect = 2e-07
Identities = 106/528 (20%), Positives = 215/528 (40%), Gaps = 74/528 (14%)
Query: 401 DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELR 460
++ + A++ + L E E Q++ + + + Q QEN L+D R
Sbjct: 252 ELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQ-----QENMNLLSDARSAR 306
Query: 461 NHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQL 520
+ R E+ EK ++ V + E + +E I +Y++ + +LKE ++ L
Sbjct: 307 MY----RDELDALREKAVR---VDKLESEVSRYKERLHDIEFYKA---RVEELKEDNQVL 356
Query: 521 LSTE-QVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTV 579
L T+ + DQ A S LHE ++K++L + D+
Sbjct: 357 LETKTMLEDQLEGTRARS---------DKLHE-LEKENLQLKAKLHDM------------ 394
Query: 580 SLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHV---LNQTLAEVLFPMDNKMDKMS 636
EME++ R + E+++ + Q + +E+LH+ L Q ++ + +
Sbjct: 395 --EMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQ-ISRTSELSEAPQKSLG 451
Query: 637 EQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELT 696
++N+LT L L + SL T T E+ + + +E S + + + L+
Sbjct: 452 HEVNELTSSR--LLKLEMENQSL--TKTVEELRTTV---DSVEGNASKILKMEKENQRLS 504
Query: 697 KRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIK 756
K+ +L NE+ +L+ N L+K D +++ L++T+ T++
Sbjct: 505 KKVEILENEIVQEKQSLQNCQN---------LSK---------DLMKEKAQLEKTIETLR 546
Query: 757 DNSEIHHKCTSDMETIL--TFIPQFHRLNDSIQTLVNDNQRYNFVL--QVAKTLAGIPRD 812
+NSE K L T R S + V D ++ N +L + +T + + +
Sbjct: 547 ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKI 606
Query: 813 EKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQT 872
E + +K + + E + + + + HLE++ L K N + + IE+ +
Sbjct: 607 E-FEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQEN 665
Query: 873 LIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSL 920
+ K + + ++ QL+ L L+ +++ L N SL
Sbjct: 666 SELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESL 713
Score = 47.4 bits (111), Expect = 9e-05
Identities = 129/664 (19%), Positives = 249/664 (37%), Gaps = 134/664 (20%)
Query: 325 TDQVNYQAMKLTLLQKKID-NISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSI 383
T Q+N KLT +KI N ++D ++T +D+ + +S L+ KS+
Sbjct: 918 TQQMNNDLEKLTHELEKIGLNKERLLHDEQST---------DDRYKLLESKLESTLKKSL 968
Query: 384 NVLIRDIVREQFKIFQN-DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQK 442
+ I + ++ ++ + + + Q KTV E L+ + + V S K
Sbjct: 969 EIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNK 1028
Query: 443 FVLVQENRPTLTDIVELRNHIVNV-RQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSIL 501
+ +E++ T +++++++ ++ V R TL EK + ++KQ +
Sbjct: 1029 WE--RESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQN----------- 1075
Query: 502 YYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMML 561
N +++ + Q +S ++ + A+ N T + QS ++
Sbjct: 1076 -----NNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENST---------LNSQSTSLM 1121
Query: 562 QMFEDLHIQESKINNLTVSLEMEKESLR---------------------GECEDMLSKCR 600
L IQ+S + N S+ E+E L+ E E ++SK
Sbjct: 1122 NQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISK-- 1179
Query: 601 NDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLR 660
LK +NL V ++ L + N++ K QL DL +++ EQ L
Sbjct: 1180 ---HGTLKSAHKNLEVEHRDLED----RYNQLLKQKGQLEDLEKMLKV-----EQEKMLL 1227
Query: 661 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALER-RINE 719
+ +E + + + L + LN +L K +L+ + + L ++ +
Sbjct: 1228 ENKNHE------TVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQ 1281
Query: 720 YALEME--------DGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSD-ME 770
LE E L+ T T +NN E LS +K N E ++ D ++
Sbjct: 1282 TRLEAEFSKLKEQYQQLDITSTKLNNQC----------ELLSQLKGNLEEENRHLLDQIQ 1331
Query: 771 TILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMF--- 827
T++ N + L + QR Q L + R ++ + Y+ +
Sbjct: 1332 TLMLQNRTLLEQNMESKDLFHVEQR-----QYIDKLNELRRQKEKLEEKIMDQYKFYDPS 1386
Query: 828 ------NETTSQVRKYQQNMSHL----EEKLLLTTKISKNFETRLQDIESKVTQTLIPYY 877
N T ++RK ++ + ++ L LT S + E LQ +P+
Sbjct: 1387 PPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTRSDSSEGFLQ----------LPHQ 1436
Query: 878 ISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTS 937
S SV +N + L S AL+ + F + + C+ S S
Sbjct: 1437 DSQDSSSVGSNSLEDGQTLGTKKSSMVALK------RLPFLRNRPKDKDKMKACYRRSMS 1490
Query: 938 VSEL 941
+++L
Sbjct: 1491 MNDL 1494
>gi|221316695 multimerin 2 precursor [Homo sapiens]
Length = 949
Score = 85.5 bits (210), Expect = 3e-16
Identities = 122/519 (23%), Positives = 207/519 (39%), Gaps = 81/519 (15%)
Query: 165 IGGVGGTGGVGNRAPRETYLSRGDSSSSQRTDYQKSNFETTR----GKNWCAYVHTRLSP 220
+GG G G +G A + S D SS+ K+ E T G+NWC Y ++L
Sbjct: 9 LGGPLGWGLLGAWAQASS-TSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVT 67
Query: 221 TVILDNQVTYVPGGKGPCGWTGGSCPQRS---QKISNPVYRMQHKIVTSLDWRCCPGYSG 277
+ L ++ + PC C + + PVY+++ K++TSL WRCCPGY+G
Sbjct: 68 LLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTG 127
Query: 278 PKCQLR--------------AQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQK 323
P C+ QE Q + + AV V QQ+QQ ++
Sbjct: 128 PNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQ----EHLLGD 183
Query: 324 MTDQVNYQAMKLTLLQKKI-DNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKS 382
+ + V+ A L L K + N++ V + T G D+S E Q LL + +
Sbjct: 184 LQNDVHRVADSLPGLWKALPGNLTAAVMEANQT-----GHEFPDRSLE-QVLLPHVDT-- 235
Query: 383 INVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQK 442
++ F +++ L + + +LS D+E+ RQ I +V +S V+ A Q+
Sbjct: 236 -------FLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQE 288
Query: 443 F-----VLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHS 497
VQEN + +LR + + T + I EL Q ++ L++ H
Sbjct: 289 LGAKFEAKVQENTQR---VGQLRQDVEDRLHAQHFTLHRSISEL---QADVDTKLKRLHK 342
Query: 498 RSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQS 557
N +L +L+T + + ++ + +S LH ++
Sbjct: 343 AQ--EAPGTNGSL---------VLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARRE 391
Query: 558 LMMLQMFEDL------HIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTE 611
+ ED+ H+ E K E+ ES E D +SK + +L+
Sbjct: 392 EELQYTLEDMRATLTRHVDEIK--------ELYSES--DETFDQISKVERQVE-ELQVNH 440
Query: 612 ENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQ 650
L L L E M+ +++ QL +L ++ LQ
Sbjct: 441 TALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQ 479
Score = 67.0 bits (162), Expect = 1e-10
Identities = 42/128 (32%), Positives = 62/128 (48%), Gaps = 4/128 (3%)
Query: 1101 VAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTIESFSAHISG 1160
VAF+AS + G + FN +N G+SY P G FR P GVY+F ++E +G
Sbjct: 826 VAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTG 885
Query: 1161 FLVVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQEVWLRLAKGTIPAKFPPVTTF 1220
LV G + + S T A+ EL G+ VW L +G+I + T F
Sbjct: 886 QLVFGGHHRTPVCTTGQGS----GSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAF 941
Query: 1221 SGYLLYRT 1228
G+L+++T
Sbjct: 942 GGFLMFKT 949
>gi|60498978 elastin microfibril interfacer 2 [Homo sapiens]
Length = 1053
Score = 83.6 bits (205), Expect = 1e-15
Identities = 198/1004 (19%), Positives = 370/1004 (36%), Gaps = 142/1004 (14%)
Query: 204 TTRGKNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGWTGGSCPQRSQKISN--PVYRMQH 261
+ R KNWCAY+ + +L+ +++ C W CP N P Y ++
Sbjct: 41 SARNKNWCAYIVNKNVSCSVLEGSESFIQAQYN-CAWNQMPCPSALVYRVNFRPRYVTRY 99
Query: 262 KIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQ--------- 312
K VT L+WRCCPG+ G CQ ++ + A ++ + + Q
Sbjct: 100 KTVTQLEWRCCPGFRGGDCQEGPKDPVKTLRPTPARPRNSLKKATDNEPSQFSEPRKTLS 159
Query: 313 -QGCGDPE--VMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYS----SLEGKVSE 365
G P V K Q Q K+ +L++K+ ++ TV D++++ + +L+ +
Sbjct: 160 PTGTAQPSWGVDPKEGPQ-ELQEKKIQVLEEKVLRLTRTVLDLQSSLAGVSENLKHATQD 218
Query: 366 DKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQ 425
D SR L K + D Q N + + + ++ + + L++
Sbjct: 219 DASRTRAPGLSSQHPKPDTTVSGDTETGQSPGVFNTKESGMKDIKSELAEVKDTLKNKSD 278
Query: 426 IIQKVNESVVSIAAQQKFVLVQENRPTLTDIVE------LRNHIVNVRQEMTLTCEKPIK 479
+++++ V Q + + PT+T + + I +R+E+ ++ +
Sbjct: 279 KLEELDGKVKGYEGQLRQLQEAAQGPTVTMTTNELYQAYVDSKIDALREELMEGMDRKLA 338
Query: 480 EL----EVKQTHLEGALEQEHSRSILYYESL-NKTLSKLKEVHEQLLSTEQVSDQKNAPA 534
+L E K T L+ + S + E + K S KE++ ++ S Q N
Sbjct: 339 DLKNSCEYKLTGLQQQCDDYGSSYLGVIELIGEKETSLRKEINNLRARLQEPSAQANCCD 398
Query: 535 AESVSNNVTEYMSTLHENIKK--QSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGEC 592
+E + ++ + + TL + I++ ++ ML D + V + + L
Sbjct: 399 SEK-NGDIGQQIKTLDQKIERVAEATRMLNGRLDNEFDRLIVPEPDVDFDAKWNELDARI 457
Query: 593 EDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPL 652
++ K + F +++T +N + ++ +D K+ + ++L + +LQ
Sbjct: 458 -NVTEKNAEEHCFYIEETLRG--AINGEVGDLKQLVDQKIQSLEDRLGSV-----LLQMT 509
Query: 653 LEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDA 712
GA L P A + + LN + ++ ++ +QG+
Sbjct: 510 NNTGAEL------SPPGAAALPGVSGSGDERVMMELNHLKDKVQVVEDICLLNIQGKPHG 563
Query: 713 LERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKD-NSEIHHKCTSDMET 771
+E + +++ A++++L +K N +H K +T
Sbjct: 564 MEGALPN-----------------------REDRAVRDSLHLLKSLNDTMHRKFQETEQT 600
Query: 772 ILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETT 831
I F L + ND V + K ++ E F K+ + T
Sbjct: 601 IQKLQQDFSFLYSQLNHTEND------VTHLQKEMSNCRAGENAGMGRFTKVGEQ-ERTV 653
Query: 832 SQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERD 891
+ Q ++H +L E R Q ++S+V L E
Sbjct: 654 DTLPSPQHPVAHCCSQL----------EERWQRLQSQVISEL-----------DACKECT 692
Query: 892 QALQLQV--LNSRFKALE---AKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIP 946
Q +Q +V + R +E +K +S N + + L++ ++ N V ++N T+
Sbjct: 693 QGVQREVSMVEGRVSHMEKTCSKLDSISGNLQRIKEGLNKHVSSLWNC---VRQMNGTLR 749
Query: 947 KWIKHSLPDIQLLQKGLTEFVEPIIQIKTQAA-LSNLTCCIDRSLPGSLANVVKSQKQVK 1005
HS DI L+ + +F + QI T L P A K Q +
Sbjct: 750 ---SHS-RDISGLKNSVQQFYSHVFQISTDLQDLVKFQPSAKAPSPPPPAEAPKEPLQPE 805
Query: 1006 SLPKKINALKKPTVNLTTVLIGR----TQRNTDNIIYPEEYSSCSRHPCQNG------GT 1055
P +P+ T GR QR + P + + + G G
Sbjct: 806 PAP------PRPSGPATAEDPGRRPVLPQRPPEE--RPPQPPGSTGVIAETGQAGPPAGA 857
Query: 1056 CINGRTSFTCACRHPFTGDNCTIKLVEENALAPDFSKGSYRYAP--MVAFFASHTYGMTI 1113
++GR +G T+ E A AP + K +P V S + G+T
Sbjct: 858 GVSGRGLPRGVDGQTGSG---TVPGAEGFAGAPGYPKSPPVASPGAPVPSLVSFSAGLTQ 914
Query: 1114 P------GPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTI 1151
G +LFN + VN G Y P TG F PY G Y+ T+
Sbjct: 915 KPFPSDGGVVLFNKVLVNDGDVYNPSTGVFTAPYDGRYLITATL 958
>gi|5901944 elastin microfibril interfacer 1 [Homo sapiens]
Length = 1016
Score = 82.0 bits (201), Expect = 3e-15
Identities = 60/235 (25%), Positives = 100/235 (42%), Gaps = 13/235 (5%)
Query: 173 GVGNRAPRETYLSRGDSS--SSQRTDYQKSNFETTRGKNWCAYVHTRLSPTVILDNQVTY 230
G + PR L G S S Q + +R +NWCAYV TR V+ D TY
Sbjct: 20 GAASYPPRGFSLYTGSSGALSPGGPQAQIAPRPASRHRNWCAYVVTRTVSCVLEDGVETY 79
Query: 231 VPGGKGPCGWTGGSCPQRS--QKISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQ 288
V PC W CPQ ++ P YR+ +K VT ++WRCC GY G C E
Sbjct: 80 VK--YQPCAWGQPQCPQSIMYRRFLRPRYRVAYKTVTDMEWRCCQGYGGDDC----AESP 133
Query: 289 SLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLT 348
+ + + + R G P + + + ++ K+ L++++ +++
Sbjct: 134 APALGPASSTPRPLARPARPNLSGSSAGSP--LSGLGGEGPGESEKVQQLEEQVQSLTKE 191
Query: 349 VNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQ 403
+ +R L G+++ED R ++ G + + + R V E Q+ +Q
Sbjct: 192 LQGLRGVLQGLSGRLAEDVQRAVETAFNG-RQQPADAAARPGVHETLNEIQHQLQ 245
Score = 46.2 bits (108), Expect = 2e-04
Identities = 41/140 (29%), Positives = 60/140 (42%), Gaps = 12/140 (8%)
Query: 1099 PMVAFFASHTYGMTIPGPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTI-----ES 1153
P VAF A+ + + PG + F+ + +N G Y P TG F P G Y+ + E
Sbjct: 869 PQVAFSAALSLPRSEPGTVPFDRVLLNDGGYYDPETGVFTAPLAGRYLLSAVLTGHRHEK 928
Query: 1154 FSAHIS-GFLVVDGIDKLAFESENI-NSEIHCDRVLTG-----DALLELNYGQEVWLRLA 1206
A +S V +D +E E + N + + G +L L G V + L
Sbjct: 929 VEAVLSRSNQGVARVDSGGYEPEGLENKPVAESQPSPGTLGVFSLILPLQAGDTVCVDLV 988
Query: 1207 KGTIPAKFPPVTTFSGYLLY 1226
G + P+T FSG LLY
Sbjct: 989 MGQLAHSEEPLTIFSGALLY 1008
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 77.0 bits (188), Expect = 1e-13
Identities = 162/773 (20%), Positives = 324/773 (41%), Gaps = 100/773 (12%)
Query: 251 KISNPVYRMQHKIVTSLDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQ 310
K+S +++ K+ S + + + K + + QEQQ+L + A+ A + EQ
Sbjct: 461 KLSRLEEQLKEKVTNSTELQ----HQLDKTKQQHQEQQALQQSTTAKLREA--QNDLEQV 514
Query: 311 QQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSL---EGKVS--- 364
+Q GD + QK+ N +A LLQK +NISL + + Y+ + EG+ +
Sbjct: 515 LRQ-IGDKD--QKIQ---NLEA----LLQKSKENISLLEKEREDLYAKIQAGEGETAVLN 564
Query: 365 --EDKSREFQSLLKGLKSKSINVL---------IRDIVREQFKIFQNDMQETVAQLFKTV 413
++K+ Q + L K N + D V+EQ K Q+ V L +V
Sbjct: 565 QLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQ-KAHLRAAQDRVLSLETSV 623
Query: 414 SSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT 473
+ L+ L ++ +KV++ + I A+ + +L E T +L+NH+ T
Sbjct: 624 NELNSQLNESK---EKVSQLDIQIKAKTELLLSAEAAKT-AQRADLQNHLD--------T 671
Query: 474 CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAP 533
+ +++ + + + L+Q ++ E ++ S LKE E+ LS EQ +++
Sbjct: 672 AQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQ 731
Query: 534 AAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQ-ESKINNLTVSLEMEKESLRGEC 592
+ ++++ S K+Q+L LQ L+ E + L+ LEMEKE +
Sbjct: 732 IKKLEADSLEVKAS------KEQALQDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTR 785
Query: 593 EDMLSKCR--NDFKFQLKDTEENLHVLNQ---TLAEVL----FPMDNKMDKMSEQLNDLT 643
D+ K K +L EE +L Q TL++ ++N++ +L +
Sbjct: 786 LDLQKKSEALESIKQKLTKQEEEKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVK 845
Query: 644 YDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLR 703
+ E L L ++ K+ + +A+ L KEL +H L
Sbjct: 846 MEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKGKAAILDLEKTCKEL--KHQL-- 901
Query: 704 NEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHH 763
+VQ + E++ + +LE E + + + N++ L + +T+K N +
Sbjct: 902 -QVQMENTLKEQKELKKSLEKEKEASHQLKLELNSM-----QEQLIQAQNTLKQNEKEEQ 955
Query: 764 KCTSDMETILTFIPQFHRLNDSIQTLVN---------DNQRYNFVLQVAKTLAGIPRDEK 814
+ ++ + Q + +++Q + +N+ + Q A+ LA
Sbjct: 956 QLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAAEKEKIS 1015
Query: 815 LNQSNFQKMYQMFNE-------TTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIES 867
+ Q+N++K + F + S++ +Q++ +EEKL L + + ++ + ++
Sbjct: 1016 VLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGN-QN 1074
Query: 868 KVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSL---NKTL 924
K+ Q L K + T E+D A + Q L R KAL+ S+ L L
Sbjct: 1075 KLIQEL--------KTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKL 1126
Query: 925 HEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQA 977
E+ + +++LN + S+ +I L+ ++ ++++ +A
Sbjct: 1127 AEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKA 1179
Score = 70.9 bits (172), Expect = 7e-12
Identities = 162/797 (20%), Positives = 324/797 (40%), Gaps = 105/797 (13%)
Query: 287 QQSLIHTNQAESHTAVGR--GVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDN 344
+ ++++ Q ++HT + + E+ + Q + + + DQV Q L Q ++ +
Sbjct: 559 ETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLS 618
Query: 345 ISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQE 404
+ +VN++ + + + KVS+ + L +++ R ++ QN +Q+
Sbjct: 619 LETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQD 678
Query: 405 TVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTL-TDIVELRNHI 463
+L K + L Q+ K+ + QE+ L + + E +
Sbjct: 679 KQQELNKITTQLD-------QVTAKLQDK-------------QEHCSQLESHLKEYKEKY 718
Query: 464 VNVRQEMTLTCEKPIKELEVKQTHLEGALEQ-----EHSRSILYYESLNKT-LSKLKEVH 517
+++ Q+ T E IK+LE ++ + EQ + R + L T LSK E+
Sbjct: 719 LSLEQK-TEELEGQIKKLEADSLEVKASKEQALQDLQQQRQLNTDLELRATELSKQLEME 777
Query: 518 EQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINN- 576
++++S+ ++ QK + A ES+ +T+ + I KQ L ++ IQ ++NN
Sbjct: 778 KEIVSSTRLDLQKKSEALESIKQKLTKQEE--EKQILKQDFETLS--QETKIQHEELNNR 833
Query: 577 --LTVS----LEMEKESLRGE---CEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFP 627
TV+ ++MEKE+L E +D LSK + LK+++ NQ +
Sbjct: 834 IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSD----SLKNSKSEFEKENQKGKAAILD 889
Query: 628 MDNKMDKMSEQL-----NDLTYDMEILQPL-LEQGASLRQTMTYEQPKEAIV-------- 673
++ ++ QL N L E+ + L E+ AS + + +E ++
Sbjct: 890 LEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQ 949
Query: 674 IRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQ-------GRDDALERRINEYALEMED 726
K+ + L +N L ++ K+ L+ E++ ++ L++++ + A E+
Sbjct: 950 NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQAAQELAA 1009
Query: 727 GLNKTMTIINN------AIDFIQDNYALKET--LSTIKDNSEIHHKCTSDMETILTFIPQ 778
K + NN +Q ++ +E+ L+T +D + K + E +++ Q
Sbjct: 1010 EKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDLISNRNQ 1069
Query: 779 FHRLNDSIQ-------TLVNDNQRYNFVLQV-AKTLAGIPRDEKLNQSNFQKMYQMFNET 830
N IQ TL D+ + LQ K L I +++ L + E
Sbjct: 1070 IGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEKSKLAEI 1129
Query: 831 TSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYY--ISVKKGSVVTN 888
+ ++ ++ L E+L S T L+D + + Q + K +V
Sbjct: 1130 EEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLKAAVEQE 1189
Query: 889 ERDQAL-------QLQVLNSRFKALEAKSIHLSINFFSLNKTLHE----VLTMCHNASTS 937
+R+Q + + + L F EAK +H I + HE LTM T+
Sbjct: 1190 KRNQQILKDQVKKEEEELKKEFIEKEAK-LHSEIKEKEVGMKKHEENEAKLTM---QITA 1245
Query: 938 VSELNATIPKWIKHSLPDIQLLQKGLTEFVEPI--IQIKTQAALSNLTCCIDRSLPGSLA 995
++E T+ K + S + L+K + I ++ Q ++R L G
Sbjct: 1246 LNENLGTVKKEWQSSQRRVSELEKQTDDLRGEIAVLEATVQNNQDERRALLERCLKGE-G 1304
Query: 996 NVVKSQKQVKSLPKKIN 1012
+ K Q +V L +K++
Sbjct: 1305 EIEKLQTKVLELQRKLD 1321
Score = 62.8 bits (151), Expect = 2e-09
Identities = 163/829 (19%), Positives = 324/829 (39%), Gaps = 128/829 (15%)
Query: 275 YSGPKCQLRAQEQQSLIHTNQAESHTAVGRGV-AEQQQQQGCGDPEVMQKMTDQVNYQAM 333
Y + A EQ+ T + V + + E Q+ G D V++K QV
Sbjct: 179 YDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMD 238
Query: 334 KLTL-LQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVR 392
+TL +++ + + +++ Y+S E +S+ +S L KG + + V ++++ +
Sbjct: 239 NMTLERERESEKLKDECKKLQSQYASSEATISQLRSE----LAKG--PQEVAVYVQELQK 292
Query: 393 EQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQ----IIQKVNESVVS-----IAAQQKF 443
++ +V +L + +L+E+L Q + +K NE VS QK
Sbjct: 293 ---------LKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKD 343
Query: 444 VLVQE--NRPTLTDIVELRNHI-VNVRQEMTLTCEKPIKELEVKQTHLEGAL-------E 493
+ Q+ +R + ++ R H+ ++ + E T ++ + E+E K HL+ E
Sbjct: 344 LDCQQLQSRLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQRE 403
Query: 494 QEHSRSILYYESLNKTLSKLKEV-------HEQLLSTEQVSDQKNAPAAESVSN------ 540
++ + +N+ SKL E H +L Q+S +K + V++
Sbjct: 404 EKEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLS 463
Query: 541 -----------NVTEYM----STLHENIKKQSLM-------------MLQMFEDLHIQES 572
N TE T ++ ++Q+L + Q+ + ++
Sbjct: 464 RLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKDQ 523
Query: 573 KINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKM 632
KI NL L+ KE++ +L K R D +++ E VLNQ + K
Sbjct: 524 KIQNLEALLQKSKENI-----SLLEKEREDLYAKIQAGEGETAVLNQ--------LQEKN 570
Query: 633 DKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFII 692
+ EQ+ LT ++ +Q EQ + ++ +L ++VN LN +
Sbjct: 571 HTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQL 630
Query: 693 KELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQD----NYAL 748
E ++ + L +++ + + L + D N T N D Q+ L
Sbjct: 631 NESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQL 690
Query: 749 KETLSTIKDNSEIHHKCTSDM----ETILTFIPQFHRLNDSIQTLVNDNQRYNF----VL 800
+ + ++D E + S + E L+ + L I+ L D+ L
Sbjct: 691 DQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQKTEELEGQIKKLEADSLEVKASKEQAL 750
Query: 801 QVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVR----KYQQNMSHLEEKLLLTTKISK 856
Q + + D +L + K +M E S R K + + +++KL TK +
Sbjct: 751 QDLQQQRQLNTDLELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKL---TKQEE 807
Query: 857 NFETRLQDIESKVTQTLIPY-YISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSI 915
+ QD E+ +T I + ++ + + VT + ++ + L + ++ K LS
Sbjct: 808 EKQILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDK---LSK 864
Query: 916 NFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKH--------SLPDIQLLQKGLTEFV 967
SL + E ++ +L T K +KH +L + + L+K L +
Sbjct: 865 VSDSLKNSKSEFEKENQKGKAAILDLEKTC-KELKHQLQVQMENTLKEQKELKKSLEKEK 923
Query: 968 EPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKK 1016
E Q+K + + L + + +++K+ + L IN LK+
Sbjct: 924 EASHQLKLELN------SMQEQLIQAQNTLKQNEKEEQQLQGNINELKQ 966
Score = 50.4 bits (119), Expect = 1e-05
Identities = 97/540 (17%), Positives = 214/540 (39%), Gaps = 52/540 (9%)
Query: 510 LSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHI 569
++ +K +++ S + ++QK E ++ T E +++ + + + + +
Sbjct: 172 IADIKSKYDEERSLREAAEQKVTRLTEELNKEATVIQDLKTELLQRPGIEDVAVLKKELV 231
Query: 570 Q-ESKINNLTVSLEMEKESLRGEC----------EDMLSKCRNDFK-------------F 605
Q ++ ++N+T+ E E E L+ EC E +S+ R++
Sbjct: 232 QVQTLMDNMTLERERESEKLKDECKKLQSQYASSEATISQLRSELAKGPQEVAVYVQELQ 291
Query: 606 QLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQ-GASLRQTMT 664
+LK + L NQTL E L + K+ E+ N+ + + +Q L Q +Q +
Sbjct: 292 KLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQQLQS 351
Query: 665 YEQPKEAIVIRKKIE--NLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEYAL 722
E + R +E A L + E+ ++ L+ E + E + ++ L
Sbjct: 352 RLSASETSLHRIHVELSEKGEATQKLKEELSEVETKYQHLKAEFKQLQQQREEK-EQHGL 410
Query: 723 EMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIP-QFHR 781
+++ +N+ + ++ L E +K+ ++ + D E + + + R
Sbjct: 411 QLQSEINQLHS------KLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLSR 464
Query: 782 LNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKY---Q 838
L + ++ V ++ Q+ KT + L QS K+ + N+ +R+
Sbjct: 465 LEEQLKEKVTNSTELQH--QLDKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGDKD 522
Query: 839 QNMSHLEEKLLLTTKISKNFETRLQDIESKVT----QTLIPYYISVKKGSVVTNERDQAL 894
Q + +LE L + + E +D+ +K+ +T + + K ++ ++Q
Sbjct: 523 QKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQEKNHTL----QEQVT 578
Query: 895 QL-QVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSL 953
QL + L ++ ++ + +L L + TSV+ELN+ + + K +
Sbjct: 579 QLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNE-SKEKV 637
Query: 954 PDIQLLQKGLTEFVEPIIQIKT--QAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKI 1011
+ + K TE + KT +A L N +L + K Q+ + K+
Sbjct: 638 SQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQNALQDKQQELNKITTQLDQVTAKL 697
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 76.6 bits (187), Expect = 1e-13
Identities = 115/599 (19%), Positives = 261/599 (43%), Gaps = 55/599 (9%)
Query: 338 LQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI 397
LQ K+D + ++ S L G++SE ++ + + ++ + + + + Q K
Sbjct: 1390 LQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKE 1449
Query: 398 FQN---DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSI--AAQQKFVLVQENRPT 452
+Q + ++ + + E+ + +QI +K+ +++S A ++ L +E
Sbjct: 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1509
Query: 453 LTDIVELRNHIVNVRQEMTLTCEKP---IKELEVKQTHLEGALEQEHSRSILYYESLNKT 509
I L + +V +++ ++ + L + Q + L E RS+L +SL+ +
Sbjct: 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERD-KLITEMDRSLLENQSLSSS 1568
Query: 510 LSKLKEVHEQLLS-----TEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMF 564
LK E L +++ K++ AES TE+ H+ ++K+ ++LQ +
Sbjct: 1569 CESLKLALEGLTEDKEKLVKEIESLKSSKIAES-----TEWQEK-HKELQKEYEILLQSY 1622
Query: 565 EDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEV 624
E++ + +I ++ ++ EK+ L G+ + + + + QL++ E+ + + + + +
Sbjct: 1623 ENVSNEAERIQHVVEAVRQEKQELYGKLRSTEAN-KKETEKQLQEAEQEMEEMKEKMRKF 1681
Query: 625 LFPMDNKMDKMSEQLNDLTYDM--------EILQPLLEQGASLRQTMTYEQPK-EAIVIR 675
K+ ++ E+ + L ++ E ++ LL AS+++ + E+ K E +
Sbjct: 1682 AKSKQQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEEL--ERVKMEYETLS 1739
Query: 676 KKIENLTSAVNSLNFIIKELTKRHNLLRN-EVQGRDDALERRINEYALEMEDGLNKTMTI 734
KK ++L S +SL+ +++L +H + N Q +A E+ N+ + E T +I
Sbjct: 1740 KKFQSLMSEKDSLSEEVQDL--KHQIEGNVSKQANLEATEKHDNQTNVTEEG----TQSI 1793
Query: 735 INNAIDFIQDNYAL------KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQT 788
+ QD+ ++ E++ + K + K S + I ++ Q +L + I
Sbjct: 1794 PGETEE--QDSLSMSTRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAG 1851
Query: 789 LVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKL 848
L + Q+ Q + + + KM Q +V K ++E+L
Sbjct: 1852 LEEEKQKNKEFSQTLENEKNTLLSQISTKDGELKMLQ------EEVTKMNLLNQQIQEEL 1905
Query: 849 LLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALE 907
TK+ + E D+E ++ L S+ G+ + D ++ ++L S K L+
Sbjct: 1906 SRVTKLKETAEEEKDDLEERLMNQLAELNGSI--GNYCQDVTDAQIKNELLESEMKNLK 1962
Score = 55.5 bits (132), Expect = 3e-07
Identities = 147/796 (18%), Positives = 309/796 (38%), Gaps = 87/796 (10%)
Query: 281 QLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQK 340
+LRAQ +Q ++ +AE + E Q E + ++ + + +K+ +LQ
Sbjct: 761 ELRAQVKQLEMNLAEAERQRRLDY---ESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN 817
Query: 341 KIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSL--LKGLKSKSINVLIRDIVREQFKIF 398
++D++ L ++ SL+ ++ +S + ++ + SK + L + + +++ +I
Sbjct: 818 ELDDVQLQFSEQSTLIRSLQSQLQNKESEVLEGAERVRHISSK-VEELSQALSQKELEIT 876
Query: 399 QNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVE 458
+ D + + D+E+ +Q I++ ++ V I+ +VQ N + VE
Sbjct: 877 KMD---------QLLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVE 927
Query: 459 LRNHIVNVRQEMTL--TCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEV 516
++ +++++ L E+ KE + + L+Q + S +SK +
Sbjct: 928 IK----TLKEQLNLLSRAEEAKKEQVEEDNEVSSGLKQNYDEM-----SPAGQISKEELQ 978
Query: 517 HE-QLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHE---NIKKQSLMMLQMF-------- 564
HE LL E ++ AA + + +S L E N+K +S + +
Sbjct: 979 HEFDLLKKENEQRKRKLQAALINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVE 1038
Query: 565 ---EDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTL 621
E+ E + + +E+ + E E L R D + +L EE L + +
Sbjct: 1039 EDKENKEYSEKCVTSKCQEIEIYLKQTISEKEVELQHIRKDLEEKLA-AEEQFQALVKQM 1097
Query: 622 AEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVI------- 674
+ L N++D + ++++ + I+Q L+ + KE +VI
Sbjct: 1098 NQTLQDKTNQIDLLQAEISE---NQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGS 1154
Query: 675 --------RKKI-----------ENLTSAVNSLNFIIKELTKRHNLLRNEV-QGRDD--A 712
+KI + L A+ S I+K+ ++ LR E+ Q +DD
Sbjct: 1155 SEHWKPELEEKILALEKEKEQLQKKLQEALTSRKAILKKAQEKERHLREELKQQKDDYNR 1214
Query: 713 LERRINEYALEME---DGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDM 769
L+ + +E + E E D L + + +ID + +E+ S+ E K T
Sbjct: 1215 LQEQFDEQSKENENIGDQLRQLQIQVRESIDGKLPSTDQQESCSSTPGLEEPLFKATEQH 1274
Query: 770 ETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNE 829
T L ++ + LQ ++A I K ++ ++ +
Sbjct: 1275 HTQPV-------LESNLCPDWPSHSEDASALQGGTSVAQIKAQLKEIEAEKVELELKVSS 1327
Query: 830 TTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNE 889
TTS++ K + + L+E++ ++ +T + E S + + + +
Sbjct: 1328 TTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQKLESSQLQIAGLEHL 1387
Query: 890 RDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWI 949
R+ +L L E +LS L ++ T + L+ +
Sbjct: 1388 RELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQA 1447
Query: 950 KHSLPDIQLLQKGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPK 1009
K I+ LQ L E + +I ++ I R L +L + ++ K+ KSL +
Sbjct: 1448 KEHDERIKQLQVELCEMKQKPEEIGEESRAKQQ---IQRKLQAALISRKEALKENKSLQE 1504
Query: 1010 KINALKKPTVNLTTVL 1025
+++ + LT L
Sbjct: 1505 ELSLARGTIERLTKSL 1520
Score = 52.8 bits (125), Expect = 2e-06
Identities = 121/616 (19%), Positives = 253/616 (41%), Gaps = 76/616 (12%)
Query: 276 SGPKCQLRAQEQQSLIHTNQA-------ESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQV 328
S K Q++ + Q +LI +A + ++ RG E+ + + +
Sbjct: 1475 SRAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEK 1534
Query: 329 NYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIR 388
+ +L LLQ++ D + ++ S LE + + L+GL ++ L++
Sbjct: 1535 DTVLGRLALLQEERDKLITEMDR-----SLLENQSLSSSCESLKLALEGL-TEDKEKLVK 1588
Query: 389 DIVR-EQFKIFQN-DMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLV 446
+I + KI ++ + QE +L K L + E+ +++ + VV Q+K L
Sbjct: 1589 EIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEAERI-QHVVEAVRQEKQELY 1647
Query: 447 QENRPTLTDIVELRNHIVNVRQEMTLTCEK----------PIKELEVKQTHLEGALEQEH 496
+ R T + E + QEM EK I ELE + L +
Sbjct: 1648 GKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRAEVHPAG 1707
Query: 497 SRSILYYESLNKTLSKLKEVHEQL-LSTEQVSDQKNAPAAE--SVSNNVTEYMSTLHENI 553
+ E+L + + +KE E++ + E +S + + +E S+S V + + N+
Sbjct: 1708 DTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKHQIEGNV 1767
Query: 554 KKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEEN 613
KQ+ +L E N V+ E +S+ GE E+ S + + ++ +
Sbjct: 1768 SKQA--------NLEATEKHDNQTNVT-EEGTQSIPGETEEQDSLSMST-RPTCSESVPS 1817
Query: 614 LHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIV 673
N +++ F ++++ +Q++ L + L+ ++ QT+ E+
Sbjct: 1818 AKSANPAVSKD-FSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEK------ 1870
Query: 674 IRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQ---GRDDALERRINEYALEMEDGLNK 730
+ +++ L + +E+TK NLL ++Q R L+ E ++E+ L
Sbjct: 1871 -NTLLSQISTKDGELKMLQEEVTKM-NLLNQQIQEELSRVTKLKETAEEEKDDLEERLMN 1928
Query: 731 TMTIINNAIDFIQDNYALKETLSTIKDN---SEIHH--KCTSDMETILTFIPQFHRLNDS 785
+ +N +I NY T + IK+ SE+ + KC S++E +
Sbjct: 1929 QLAELNGSIG----NYCQDVTDAQIKNELLESEMKNLKKCVSELE-------------EE 1971
Query: 786 IQTLVNDNQRYNFVL--QVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSH 843
Q LV + + + + + + G + E N+S+ +++ ++ E +V++ Q++
Sbjct: 1972 KQQLVKEKTKVESEIRKEYLEKIQGAQK-EPGNKSHAKELQELLKEKQQEVKQLQKDCIR 2030
Query: 844 LEEKLLLTTKISKNFE 859
+EK+ + K E
Sbjct: 2031 YQEKISALERTVKALE 2046
Score = 47.8 bits (112), Expect = 7e-05
Identities = 135/714 (18%), Positives = 268/714 (37%), Gaps = 109/714 (15%)
Query: 309 QQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKK-------IDNISLTVNDVRNTYSSLEG 361
Q++++ E +K D+ N L ++K+ +D+ +++ ++N + G
Sbjct: 2419 QEEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKSMSSLQNDRDRIVG 2478
Query: 362 KVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQ---------NDMQETVAQLFKT 412
+ + R +L+ + LI++ E K+ + +D+ A+L
Sbjct: 2479 DYQQLEERHLSIILEK------DQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAE 2532
Query: 413 VSSLSEDLESTRQIIQKVNESVVSIAAQQ------KFVLVQENRPTLTDIVELRNHIVNV 466
+ EDL I + ++ + QQ K+ ++E + E N
Sbjct: 2533 LIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNA 2592
Query: 467 RQEMTLTCEKPIKELEVKQTHLEGALE--QEHSRSILYYESLNKTLSKLKEVHEQLLSTE 524
QE K I+ L+V + L + QE LY+ L K+KE LS
Sbjct: 2593 LQEEKQDLSKEIESLKVSISQLTRQVTALQEEGTLGLYHAQL-----KVKEEEVHRLSAL 2647
Query: 525 QVSDQKNAPAAES----VSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVS 580
S QK E V + + + + +KK+ + LH + N T +
Sbjct: 2648 FSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKE-------LKHLHHDAGIMRNETET 2700
Query: 581 LEMEKESLRGECEDMLSKCRNDFKFQLKDTEEN--LHVLNQTLAEVLFPMDNKMDKMSEQ 638
E L + +M K L T+EN L Q+ + + N D +E+
Sbjct: 2701 AEERVAELARDLVEMEQKL-------LMVTKENKGLTAQIQSFGRSMSSLQNSRDHANEE 2753
Query: 639 LNDLT--YDMEI--LQPLLEQGASLRQ----------TMTYEQPKEAIVIRKKIENLTSA 684
L++L YD + L L EQG R+ +M + + K + L S
Sbjct: 2754 LDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLEKLNQQLLSK 2813
Query: 685 VNSLNFIIKELTKRHNLLRN------EVQGRDDALERRINEYALEMEDGLNKTMTIINNA 738
L + +L +N +++ +Q D L + ++ + E+G ++ + +
Sbjct: 2814 DEQLLHLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFR-KSEEGKQRSAAQPSTS 2872
Query: 739 IDFIQDNYALKETLSTIKDNSEIHHKCTSDMET----ILTFIPQFHRLNDSIQTLVNDNQ 794
+Q +LK+ +S+++++ + K +++ I I + H L +Q + +
Sbjct: 2873 PAEVQ---SLKKAMSSLQNDRDRLLKELKNLQQQYLQINQEITELHPLKAQLQEYQDKTK 2929
Query: 795 RYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQ------VRKYQQNMSHLEE-- 846
+ ++Q + +L+Q +K +E + + Q +SHL+
Sbjct: 2930 AFQ-IMQEELRQENLSWQHELHQLRMEKSSWEIHERRMKEQYLMAISDKDQQLSHLQNLI 2988
Query: 847 -KLLLTTKISKNFETRLQDIESKVT-------QTLI--PYYISVKKGSVVTNERDQALQL 896
+L ++ ++ + + Q S T Q L+ + + + + L++
Sbjct: 2989 RELRSSSSQTQPLKVQYQRQASPETSASPDGSQNLVYETELLRTQLNDSLKEIHQKELRI 3048
Query: 897 QVLNSRFKALEAKSIHLSINFFSLNKTLHE-------VLTMCHNASTSVSELNA 943
Q LNS F L + LSI +++L E +L C V EL A
Sbjct: 3049 QQLNSNFSQLLEEKNTLSIQLCDTSQSLRENQQHYGDLLNHCAVLEKQVQELQA 3102
Score = 44.7 bits (104), Expect = 6e-04
Identities = 120/623 (19%), Positives = 225/623 (36%), Gaps = 92/623 (14%)
Query: 366 DKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQ 425
+K E Q + K L+ K EQF+ M +T+ + L ++ +
Sbjct: 1068 EKEVELQHIRKDLEEKLA-------AEEQFQALVKQMNQTLQDKTNQIDLLQAEISENQA 1120
Query: 426 IIQKVNESVVSIAAQQKFVLVQEN--------------RPTLTD---IVELRNHIVNVRQ 468
IIQK+ S + LV+E +P L + +E + +
Sbjct: 1121 IIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQLQKKL 1180
Query: 469 EMTLTCEKPI-KELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLL------ 521
+ LT K I K+ + K+ HL L+Q+ E ++ + + + +QL
Sbjct: 1181 QEALTSRKAILKKAQEKERHLREELKQQKDDYNRLQEQFDEQSKENENIGDQLRQLQIQV 1240
Query: 522 ---------STEQVSDQKNAPAAESVSNNVTEYMST---LHENI------KKQSLMMLQ- 562
ST+Q + P E TE T L N+ + LQ
Sbjct: 1241 RESIDGKLPSTDQQESCSSTPGLEEPLFKATEQHHTQPVLESNLCPDWPSHSEDASALQG 1300
Query: 563 --MFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHV--LN 618
+ Q +I V LE++ S E + K F+ Q + ++ L + L
Sbjct: 1301 GTSVAQIKAQLKEIEAEKVELELKVSSTTSE---LTKKSEEVFQLQEQINKQGLEIESLK 1357
Query: 619 QTLAEVLFPMDNKMDKMS---------EQLNDLTYDMEILQPLL---EQGASLRQTMTYE 666
E ++ K+ E L +L ++ LQ L+ E+ S E
Sbjct: 1358 TVSHEAEVHAESLQQKLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSE 1417
Query: 667 QPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERR---INEYALE 723
+ I+ +I + +L+ ++ K H+ ++Q ++++ I E +
Sbjct: 1418 KEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDERIKQLQVELCEMKQKPEEIGEESRA 1477
Query: 724 MEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDME-----------TI 772
+ K + + + +++N +L+E LS + E K +D+E T+
Sbjct: 1478 KQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQVSAQNKEKDTV 1537
Query: 773 LTFIPQFHRLNDSIQTLVN----DNQRYNFVLQVAK-TLAGIPRD-EKLNQSNFQKMYQM 826
L + D + T ++ +NQ + + K L G+ D EKL +
Sbjct: 1538 LGRLALLQEERDKLITEMDRSLLENQSLSSSCESLKLALEGLTEDKEKLVKEIESLKSSK 1597
Query: 827 FNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVV 886
E+T K+++ E L +S E R+Q + V Q Y ++ S
Sbjct: 1598 IAESTEWQEKHKELQKEYEILLQSYENVSNEAE-RIQHVVEAVRQEKQELYGKLR--STE 1654
Query: 887 TNERDQALQLQVLNSRFKALEAK 909
N+++ QLQ + ++ K
Sbjct: 1655 ANKKETEKQLQEAEQEMEEMKEK 1677
Score = 43.9 bits (102), Expect = 0.001
Identities = 121/652 (18%), Positives = 257/652 (39%), Gaps = 103/652 (15%)
Query: 319 EVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGL 378
E ++++ + + K L + D++S V D+++ +EG VS+ + E
Sbjct: 1726 EELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKH---QIEGNVSKQANLE-------A 1775
Query: 379 KSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIA 438
K N ++ E + + +E + T + SE + S + + A
Sbjct: 1776 TEKHDNQT--NVTEEGTQSIPGETEEQDSLSMSTRPTCSESVPSAKS---------ANPA 1824
Query: 439 AQQKFVLVQENRPTLTDIVELRNHIVNVRQE--------MTLTCEKP--IKELEVKQTHL 488
+ F E L I +L+ I + +E TL EK + ++ K L
Sbjct: 1825 VSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLENEKNTLLSQISTKDGEL 1884
Query: 489 EGALEQEHSRSILYYESLNKTLS---KLKE--------VHEQLLST------------EQ 525
+ L++E ++ L + + + LS KLKE + E+L++ +
Sbjct: 1885 K-MLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLMNQLAELNGSIGNYCQD 1943
Query: 526 VSD-QKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLT-VSLEM 583
V+D Q ES N+ + +S L E +KQ L+ + + I++ + + E
Sbjct: 1944 VTDAQIKNELLESEMKNLKKCVSELEE--EKQQLVKEKTKVESEIRKEYLEKIQGAQKEP 2001
Query: 584 EKESLRGECEDMLSKCRNDFKFQLKDT---EENLHVLNQTLAEVLFPMDNKMDKMSEQLN 640
+S E +++L + + + K KD +E + L +T+ + F +
Sbjct: 2002 GNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKISALERTVKALEFVQTESQKDLEITKE 2061
Query: 641 DLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHN 700
+L +E + + AS + + Q + A V+ ++ + KEL
Sbjct: 2062 NLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLK-----------LKKELQSNKE 2110
Query: 701 LLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTI----- 755
++++++ +D+ LERR+ E A E K M +A+ ++ L+ET+ I
Sbjct: 2111 SVKSQMKQKDEDLERRL-EQAEEKHLKEKKNMQEKLDALR--REKVHLEETIGEIQVTLN 2167
Query: 756 ---KDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRD 812
K+ ++ S + + F L D ++++ +++ + + + +
Sbjct: 2168 KKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWE--RKFSDAIQSKEEE 2225
Query: 813 EKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-----------KLLLTTKISKNFETR 861
+L + N + + + + + + N+S LE ++ L K+ +
Sbjct: 2226 IRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGE 2285
Query: 862 LQDIESKVTQTLIPYYIS----VKKGSVVTNERDQALQLQVLNSRFKALEAK 909
+++ S++ +T Y+ S K S + + +DQ L NS K E K
Sbjct: 2286 NKELLSQLEETRHLYHSSQNELAKLESELKSLKDQLTDLS--NSLEKCKEQK 2335
Score = 43.5 bits (101), Expect = 0.001
Identities = 124/674 (18%), Positives = 261/674 (38%), Gaps = 104/674 (15%)
Query: 279 KCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLL 338
K + + QE++ LI T QA+ + + Q +Q Q T+ + MK L
Sbjct: 148 KIKHKLQEKEELISTLQAQ--------LTQAQAEQPA------QSSTEMEEFVMMKQQLQ 193
Query: 339 QKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIF 398
+K+ +L + +V +K F++ ++ + + + ++ + V
Sbjct: 194 EKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADV------- 246
Query: 399 QNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVE 458
+ +MQ+ + L + + E L Q++ + + + + A Q+ +L Q+ + +
Sbjct: 247 ETEMQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTA-AEQRNQILSQQLQQMEAEHNT 305
Query: 459 LRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSIL--------YYESLNKTL 510
LRN + R+E + EK ELEV + L QE +L L
Sbjct: 306 LRNTVETEREESKILLEK--MELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAELESRY 363
Query: 511 SKLKEVHEQLL---STEQVSDQKNAPAAESVSNNVTEYMSTLHENIKK---QSLMMLQMF 564
S L++ H+ + ++ +S QK +S + + + S L ++ + QS +Q
Sbjct: 364 SALEQKHKAEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNEQAVQSAQTIQQL 423
Query: 565 EDLHIQESK-----INNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQ 619
ED Q+SK +N L L+ + + + D+ ++ TEEN+ L +
Sbjct: 424 EDQLQQKSKEISQFLNRL--PLQQHETASQTSFPDVYNEGTQAV------TEENIASLQK 475
Query: 620 TLAEV-------------LFPMDNKMDKMSEQLNDL-------TYDMEILQPLLEQGASL 659
+ E+ L + + +K+S Q+ L D E+ + + A+
Sbjct: 476 RVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEISIVDIANK 535
Query: 660 RQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGR--DDALERRI 717
R + E ++ V+ ++ L +KE + L+ ++QG+ ++A +
Sbjct: 536 RSSSAEESGQD--VLENTFSQKHKELSVLLLEMKEAQEEIAFLKLQLQGKRAEEADHEVL 593
Query: 718 NEYALEMEDG-----LNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETI 772
++ ++ +G + + + + DF + K+ + H+ + E
Sbjct: 594 DQKEMKQMEGEGIAPIKMKVFLEDTGQDFPLMPNEESSLPAVEKEQASTEHQSRTSEEI- 652
Query: 773 LTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLN--------QSNFQKMY 824
LND+ L + Q + L + +DE + NF K
Sbjct: 653 --------SLNDAGVELKSTKQDGDKSLSAVPDIGQCHQDELERLKSQILELELNFHKAQ 704
Query: 825 QMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGS 884
+++ + + K N++ L E+ + + T L + ++ VK+ S
Sbjct: 705 EIYEKNLDEKAKEISNLNQLIEEFKKNADNNSSAFTALSEERDQLLS-------QVKELS 757
Query: 885 VVTNERDQALQLQV 898
+VT R Q QL++
Sbjct: 758 MVTELRAQVKQLEM 771
Score = 40.0 bits (92), Expect = 0.014
Identities = 100/522 (19%), Positives = 212/522 (40%), Gaps = 63/522 (12%)
Query: 440 QQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRS 499
Q++ ++ L DI+ ++ + + E L E+ + ++K+ L H+++
Sbjct: 51 QERLAYAEQLVVELKDIIRQKDVQLQQKDE-ALQEERKAADNKIKKLKL-------HAKA 102
Query: 500 ILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLM 559
L SLNK + ++K +L TE S+++ + +S + E H+ +K+ L+
Sbjct: 103 KL--TSLNKYIEEMKAQGGTVLPTEPQSEEQLSKHDKSSTEEEMEIEKIKHKLQEKEELI 160
Query: 560 MLQMFEDLHIQESKINNLTVSLE---MEKESLRGECEDMLSKCRNDFKFQLKDTEENLHV 616
+ Q + + +E M K+ L+ E E+ +S + QL T+
Sbjct: 161 STLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQ-EKEEFIST----LQAQLSQTQAE-QA 214
Query: 617 LNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRK 676
Q + E + ++ ++L L ++ + ++ L++ + E+ +E++V R
Sbjct: 215 AQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRVLQRKL--EEHEESLVGRA 272
Query: 677 KIENLT----SAVNSLNFII----KELTKRHNLLRNEVQGRDDALERRINEYALEMEDGL 728
++ +L +A N I+ +++ HN LRN V+ ER ++ LE +
Sbjct: 273 QVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVE-----TEREESKILLEKME-- 325
Query: 729 NKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQT 788
+ + + F + L+E + + + E + +++E+ + + Q H+
Sbjct: 326 ---LEVAERKLSF----HNLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHK------- 371
Query: 789 LVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKL 848
++ + +L + KT + + K+ Q NE Q + Q + LE++L
Sbjct: 372 -AEMEEKTSHILSLQKTGQELQSACDALKDQNSKLLQDKNE---QAVQSAQTIQQLEDQL 427
Query: 849 LLTTKISKNFETRLQ-DIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSR----- 902
+K F RL +QT P + + VT E +LQ +V+
Sbjct: 428 QQKSKEISQFLNRLPLQQHETASQTSFPDVYN-EGTQAVTEENIASLQKRVVELENEKGA 486
Query: 903 --FKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELN 942
++E + + S TL E A VSE++
Sbjct: 487 LLLSSIELEELKAENEKLSSQITLLEAQNRTGEADREVSEIS 528
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 75.9 bits (185), Expect = 2e-13
Identities = 129/703 (18%), Positives = 293/703 (41%), Gaps = 82/703 (11%)
Query: 334 KLTLLQKKIDNISLTVNDVRNTYSSLEGKV---SEDKSREFQSLLKGLKSKSI-----NV 385
K + L++ ID++ LT+ V + E KV SE+ + +++ K K K
Sbjct: 950 KCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALEENISKLTKEKKSLQEAHQQ 1009
Query: 386 LIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQI--------------IQKVN 431
+ D+ E+ K+ N + + A+L + L LE +++ ++
Sbjct: 1010 TLDDLQVEEDKV--NGLIKINAKLEQQTDDLEGSLEQEKKLRADLERAKRKLEGDLKMSQ 1067
Query: 432 ESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGA 491
ES++ + K + ++ + ++ +L+ I + Q +L +K IKEL+ + LE
Sbjct: 1068 ESIMDLE-NDKQQIEEKLKKKEFELSQLQAKIDD-EQVHSLQFQKKIKELQARIEELEEE 1125
Query: 492 LEQEHSRSILYYESLNKTLSKLKEVHEQL-----LSTEQVSDQKNAPAAESVSNNVTEYM 546
+E EH+ + + +L+E+ E+L ++ Q+ K A E
Sbjct: 1126 IEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQIEMNKKREAEFQKMRRDLEEA 1185
Query: 547 STLHENI-----KKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDM------ 595
+ HE KKQ+ + ++ E Q + + LE EK L+ E +DM
Sbjct: 1186 TLQHEATAATLRKKQADSVAELGE----QIDNLQRVKQKLEKEKSELKMEIDDMASNIEA 1241
Query: 596 LSKCRNDFKFQLKDTEE---NLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPL 652
LSK +++ + + E+ + ++ +++ ++ + ++ Q +L++ +E + L
Sbjct: 1242 LSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESL 1301
Query: 653 LEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDA 712
+ Q +Q +T + + +++++E T A N++ ++ +LLR + + +A
Sbjct: 1302 ISQLTKSKQALTQQLEE----LKRQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEA 1357
Query: 713 ---LERRINEYALEMEDGLNKTMT-IINNAIDFIQDNYALKETLSTIKDNSE-IHHKCTS 767
L+R +++ E+ K T I + + L + L ++N+E + KC S
Sbjct: 1358 KAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCAS 1417
Query: 768 DMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVA--------KTLAGIPRDEKLNQSN 819
+T RL ++ L+ D +R + K LA + +Q+
Sbjct: 1418 LEKT-------KQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAE 1470
Query: 820 FQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYIS 879
+ + ++++ K + + ++L + +KN + + D+ ++ +T +
Sbjct: 1471 LEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEA 1530
Query: 880 VKKGSVVTNER-DQALQLQVLNSRFKALEAKSIHLSINFFSLNKTL--------HEVLTM 930
K +V E+ D + L+ + + E+K + + + + L E+ +
Sbjct: 1531 EKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQL 1590
Query: 931 CHNASTSVSELNATIPKWIKHSLPDIQLLQKGLTEFVEPIIQI 973
N+ + L + + I+ ++L +K + E IQ+
Sbjct: 1591 KRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQL 1633
Score = 41.2 bits (95), Expect = 0.006
Identities = 103/513 (20%), Positives = 216/513 (42%), Gaps = 95/513 (18%)
Query: 407 AQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNV 466
A+ K ++++ ED E T+ E + A++K EL +V++
Sbjct: 847 AEAEKEMATMKEDFERTK-------EELARSEARRK---------------ELEEKMVSL 884
Query: 467 RQEMTLTCEKPIKELEVKQTHLEGALE-QEHSRSILYYESLNKTLSKLKEVHEQLLSTEQ 525
QE K +L+V Q+ E ++ +E ++ + L + +K+KE+ E+L E+
Sbjct: 885 LQE------KNDLQLQV-QSETENLMDAEERCEGLIKSKILLE--AKVKELTERLEEEEE 935
Query: 526 VSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEK 585
++ + A N+ + S+L +I L + ++ ++ H E+K+ NL+ + +
Sbjct: 936 MNSELVAK-----KRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSEEMTALE 990
Query: 586 ESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMS-------EQ 638
E++ L+K + + + T ++L V + L ++ K+++ + EQ
Sbjct: 991 ENI-----SKLTKEKKSLQEAHQQTLDDLQV-EEDKVNGLIKINAKLEQQTDDLEGSLEQ 1044
Query: 639 LNDLTYDMEILQPLLEQGASLRQ--TMTYEQPKEAI--VIRKKIENLT--------SAVN 686
L D+E + LE + Q M E K+ I ++KK L+ V+
Sbjct: 1045 EKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQLQAKIDDEQVH 1104
Query: 687 SLNF--IIKELTKRHNLLRNEVQGRDD---ALERRINEYALEME---DGLNKTMTIINNA 738
SL F IKEL R L E++ +E++ ++ A E+E + L + +
Sbjct: 1105 SLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASGATSAQ 1164
Query: 739 IDFIQDNYALKETLSTIKDNSEIHHKCTS------DMETILTFIPQFHRLNDSIQTLVND 792
I+ + A + + + + + H+ T+ +++ Q L Q L +
Sbjct: 1165 IEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKE 1224
Query: 793 NQRYNFVLQ--------VAKTLAGIPRDEKLNQSNF-------QKMYQMFNETTSQVRKY 837
+ ++K+ + I R + + F ++ Q+ ++ Q +
Sbjct: 1225 KSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARL 1284
Query: 838 Q-QN--MSH-LEEKLLLTTKISKNFETRLQDIE 866
Q QN +SH +EEK L ++++K+ + Q +E
Sbjct: 1285 QTQNGELSHRVEEKESLISQLTKSKQALTQQLE 1317
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 424 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 483
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 484 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 543
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 544 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 602
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 603 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 652
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 653 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 707
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 708 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 764
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 765 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 810
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 811 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 857
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 858 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 901
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 902 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 956
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 957 VQGQMDEDVQKVLKQILTMCKNQS 980
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 413 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 472
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 473 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 532
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 533 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 591
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 592 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 641
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 642 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 696
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 697 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 753
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 754 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 799
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 800 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 846
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 847 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 890
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 891 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 945
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 946 VQGQMDEDVQKVLKQILTMCKNQS 969
>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
Length = 951
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 392 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 451
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 452 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 511
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 512 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 570
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 571 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 620
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 621 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 675
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 676 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 732
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 733 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 778
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 779 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 825
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 826 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 869
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 870 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 924
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 925 VQGQMDEDVQKVLKQILTMCKNQS 948
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 421 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 480
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 481 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 540
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 541 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 599
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 600 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 649
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 650 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 704
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 705 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 761
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 762 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 807
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 808 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 854
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 855 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 898
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 899 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 953
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 954 VQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 421 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 480
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 481 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 540
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 541 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 599
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 600 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 649
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 650 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 704
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 705 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 761
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 762 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 807
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 808 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 854
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 855 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 898
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 899 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 953
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 954 VQGQMDEDVQKVLKQILTMCKNQS 977
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 72.0 bits (175), Expect = 3e-12
Identities = 135/624 (21%), Positives = 262/624 (41%), Gaps = 116/624 (18%)
Query: 361 GKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI-FQNDMQETVA----QLFKTVSS 415
GK + D Q L + L+ + + R+Q ++ Q+ E V ++ + S
Sbjct: 421 GKSTTDNDVRIQQLQEILQDLQKRLESSEAERKQLQVELQSRRAELVCLNNTEISENSSD 480
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQ-----------ENRPTLTDIVELRNHIV 464
LS+ L+ T+ ++ + V+S+ Q K LV E R T +I L+ +
Sbjct: 481 LSQKLKETQSKYEEAMKEVLSVQKQMKLGLVSPESMDNYSHFHELRVTEEEINVLKQDLQ 540
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGAL---------EQEHSRSILYYESLNKTLSKLKE 515
N +E EK ++ELE K E E+ S E++NK + L E
Sbjct: 541 NALEESERNKEK-VRELEEKLVEREKGTVIKPPVEEYEEMKSSYCSVIENMNKEKAFLFE 599
Query: 516 VHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKIN 575
+++ + E++ K +++ + +T+ S E++K+ M +M ++L+ Q S+++
Sbjct: 600 KYQE--AQEEIMKLK-----DTLKSQMTQEASDEAEDMKEA---MNRMIDELNKQVSELS 649
Query: 576 NL--TVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
L E+E R ED+ ++ + E+ + + N + A+ +
Sbjct: 650 QLYKEAQAELEDYRKRKSLEDVTAEY-----IHKAEHEKLMQLTNVSRAKAEDALSEMKS 704
Query: 634 KMSEQLNDLTYDMEILQPLLEQGASLRQ-----TMTYEQPKEAIVIRKKIENLTSAVNSL 688
+ S+ LN+LT +++ E S+ + T KE + +KI NL + S
Sbjct: 705 QYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKE---MEEKISNLKEHLASK 761
Query: 689 NFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYAL 748
+ +L K+ LL + D + R E +++ L ++++ + L
Sbjct: 762 EVEVAKLEKQ--LLEEKAAMTDAMVPRSSYE---KLQSSLESEVSVLASK---------L 807
Query: 749 KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDN-QRYNFVLQVAKTLA 807
KE+ +K+ ++H S++ I + + Q R ++IQTL+ Q N +LQ
Sbjct: 808 KES---VKEKEKVH----SEVVQIRSEVSQVKREKENIQTLLKSKEQEVNELLQ------ 854
Query: 808 GIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEE-KLLLTTKISKNFETRLQDIE 866
+Q E +++++Y ++ S LEE K ++SK T+L++
Sbjct: 855 ---------------KFQQAQEELAEMKRYAESSSKLEEDKDKKINEMSKEV-TKLKEAL 898
Query: 867 SKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFF-------- 918
+ ++Q + Y S K +++ +ALQ QV + + E K H +
Sbjct: 899 NSLSQ--LSYSTSSSKRQ---SQQLEALQQQVKQLQNQLAECKKQHQEVISVYRMHLLYA 953
Query: 919 -------SLNKTLHEVLTMCHNAS 935
+ K L ++LTMC N S
Sbjct: 954 VQGQMDEDVQKVLKQILTMCKNQS 977
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 71.2 bits (173), Expect = 6e-12
Identities = 135/700 (19%), Positives = 311/700 (44%), Gaps = 104/700 (14%)
Query: 282 LRAQEQQSLIHTNQAESHTAVG--RGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQ 339
L QE+ ++H + E + RG+ ++ + + ++ D + Q +K+ Q
Sbjct: 1717 LEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKI---Q 1773
Query: 340 KKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVRE------ 393
+++ + + + + T L G VSE K+ + ++ K L++ N +++ ++E
Sbjct: 1774 EELRIAHMHLKEQQETIDKLRGIVSE-KTDKLSNMQKDLENS--NAKLQEKIQELKANEH 1830
Query: 394 QFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTL 453
Q + D+ ET ++ + + L + ++ + K+ +++A + + EN +
Sbjct: 1831 QLITLKKDVNETQKKVSE-MEQLKKQIKDQSLTLSKLEIENLNLAQK-----LHENLEEM 1884
Query: 454 TDIVELRNHIVNVRQEMTLTCEKPIKEL-EVKQTHLEGALEQEHSRSILYYESLNKTLSK 512
+++ R+++ V + + L ++ + L E K LE ++QE + + + +T+ K
Sbjct: 1885 KSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE--IQQELKTARMLSKEHKETVDK 1942
Query: 513 LKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQES 572
L+E + T Q+SD + + + + E + E ++K+ L +L++ ED+++
Sbjct: 1943 LREKISE--KTIQISDIQ-----KDLDKSKDELQKKIQE-LQKKELQLLRVKEDVNMSHK 1994
Query: 573 KINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKM 632
KIN EME+ + E +++ + FQL L+++L E+
Sbjct: 1995 KIN------EMEQLKKQFEAQNLSMQSVRMDNFQLTKK------LHESLEEIRI------ 2036
Query: 633 DKMSEQLNDLTYDMEILQPLLEQG-ASLRQTMTYEQPKEAIVIRKKI-----ENLTSAVN 686
++++ ++L E L+ +Q A+LR+ + ++ + K++ ++LT ++
Sbjct: 2037 --VAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLR 2094
Query: 687 SLNFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNY 746
IKEL KR++ + DD E +N +L++E I+F
Sbjct: 2095 EKCSRIKELLKRYSEM-------DDHYE-CLNRLSLDLE-----------KEIEF----- 2130
Query: 747 ALKETLSTIKDNSEIHHKCTSDMETILT----FIPQFHRLNDSIQTLVNDNQRYNFVLQV 802
KE +K N + + T +E + T +FHR+ ++ ++ ++V ++
Sbjct: 2131 -QKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVL------SYVTKI 2183
Query: 803 AKTLAGIPRDEKLN--QSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFET 860
+ + E +N + +F + E +++ QQ+ + + L K+++N +
Sbjct: 2184 KE-----EQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCD-VPSRELRDLKLNQNMDL 2237
Query: 861 RLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQV-LNSRFKALEAKSIHLSIN--F 917
+++I +++ P I + V++N ++ L+ LN+RF + K+ N
Sbjct: 2238 HIEEILKDFSESEFP-SIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNGIQKENDRI 2296
Query: 918 FSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQ 957
+N + + N ST E +ATI K + L ++
Sbjct: 2297 CQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLK 2336
Score = 65.5 bits (158), Expect = 3e-10
Identities = 149/757 (19%), Positives = 305/757 (40%), Gaps = 86/757 (11%)
Query: 321 MQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKS 380
+++++ + QAM+ L + ++ L +L + S Q LK +
Sbjct: 359 LEEVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRK 418
Query: 381 K-------SINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNES 433
+ IN + +QF I N +T + + E + S + ++
Sbjct: 419 RRVTWCLGKINKMKNSNYADQFNIPTNITTKTHKLSINLLREIDESVCSESDVFSNTLDT 478
Query: 434 VVSIAAQQKFVLV-QENRPTLTDIVELRNHIVN-VRQEMTLTCEKPIKELEVKQTH---- 487
+ I L+ QEN + ++ LR N V L EK EL++K+ +
Sbjct: 479 LSEIEWNPATKLLNQENIES--ELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDE 536
Query: 488 ---LEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTE 544
LE +++ +++ S K L K EV+ Q L E S + E + E
Sbjct: 537 FEALERKTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQE 596
Query: 545 YM-STLHENIKKQSLMMLQMFED-LHIQESKINNLTVSLEMEKES--LRGECEDMLSKCR 600
Y+ S ENIK L+ ED ++++ + TV+L+ ++ES LR E ++ K +
Sbjct: 597 YIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMK 656
Query: 601 ----------ND---FKFQLK-------DTEENLHVLNQTLAEVLFPMDNKMDKMSEQLN 640
ND ++ QL+ D E+ L + ++ +D K+ K
Sbjct: 657 ELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPK------ 710
Query: 641 DLTYDMEILQPLLEQGASL-RQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRH 699
DL ++E+ + + L ++ E +E +++ ++++L S V L I++ ++
Sbjct: 711 DLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEEL 770
Query: 700 NLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNS 759
+++ +E +D +++ + GL + + + + Q NY K T ++
Sbjct: 771 HIITSE---KDKLFSEVVHKES--RVQGLLEEIGKTKDDLATTQSNY--KSTDQEFQNFK 823
Query: 760 EIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSN 819
+H + +L + R+N I L + Q+++ L KT
Sbjct: 824 TLHMDFEQKYKMVL---EENERMNQEIVNLSKEAQKFDSSLGALKT-------------E 867
Query: 820 FQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYIS 879
Q E T +V++ M L+E+L +N ++ LQ +E + T +
Sbjct: 868 LSYKTQELQEKTREVQERLNEMEQLKEQL-------ENRDSTLQTVEREKTLITEKLQQT 920
Query: 880 VKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINF-FSLNKTLHEVLTMCHNASTSV 938
+++ +T E+D QLQ + IH ++N + L L ++
Sbjct: 921 LEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETI 980
Query: 939 SELNATIPKWIKHSLPDIQLLQKGLTEFVEPIIQI-KTQAALSNLTCCIDRSLPGSLANV 997
+ L + I + + +L + + EF + ++ I K Q + T + + + +
Sbjct: 981 NTLKSKISEEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDN--EI 1038
Query: 998 VKSQKQVKSLPKKINALKKPTVNLTTVLIGRTQRNTD 1034
++ Q+++ SL ++ N L++ L +V+ + Q TD
Sbjct: 1039 IEQQRKIFSLIQEKNELQQ---MLESVIAEKEQLKTD 1072
Score = 64.3 bits (155), Expect = 7e-10
Identities = 128/691 (18%), Positives = 277/691 (40%), Gaps = 125/691 (18%)
Query: 339 QKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIF 398
Q+KI ++ N+++ S+ + + K+ +++ ++++ L+ D +++Q +I
Sbjct: 1042 QRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIV 1101
Query: 399 QNDMQETV---AQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQEN----RP 451
+ + +L +T L+E E ++ Q++ E QQ+ + VQE +
Sbjct: 1102 AQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEK------QQQLLNVQEEMSEMQK 1155
Query: 452 TLTDIVELRNHIVNVRQEMTL------------------------TCEKPI-----KELE 482
+ +I L+N + N +E+TL T E+ + K E
Sbjct: 1156 KINEIENLKNELKN--KELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFE 1213
Query: 483 VKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLS------TEQVSDQKNAPAAE 536
++ HL G + + + + E L LKE H++ + +E+ + N E
Sbjct: 1214 TERDHLRGYIREIEATGLQTKEELKIAHIHLKE-HQETIDELRRSVSEKTAQIINTQDLE 1272
Query: 537 SVSNNVTEYMSTLHE------NIKKQSLMMLQMFE-DLHIQESKINNLTVSLEMEKESLR 589
+ E + LHE N+K+ S M E +L ++S + T +E E LR
Sbjct: 1273 KSHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLR 1332
Query: 590 GECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEIL 649
+ + + + K K+ +NL + + L + K D++ E + + ++
Sbjct: 1333 --LNEKFQESQEEIKSLTKE-RDNLKTIKEAL-------EVKHDQLKEHIRETLAKIQES 1382
Query: 650 QPLLEQGASLRQ----------TMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRH 699
Q EQ ++++ M +PK++ ++R +IE L + K L + H
Sbjct: 1383 QSKQEQSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLG--------LSKRLQESH 1434
Query: 700 NLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNS 759
+ +++ + +DD +R+ E D L + + I ++ LK +K+
Sbjct: 1435 DEMKSVAKEKDDL--QRLQEVLQSESDQLKENIKEI--VAKHLETEEELKVAHCCLKEQE 1490
Query: 760 EIHHKC---TSDMET-ILTFIPQFHRLNDSIQTLVND----NQRYNF-----VLQVAKTL 806
E ++ S+ ET I T Q +ND +Q + + +++N V + L
Sbjct: 1491 ETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNEL 1550
Query: 807 AGIPRDEKLNQSNFQKMYQMFNETTSQVR----------KYQQNMSHLEEKLLL----TT 852
K S Q + E T++++ K ++ M ++E L +
Sbjct: 1551 KQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLK 1610
Query: 853 KISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIH 912
+ +K ++++ + K Q L K + V +++ +++ L +F+ + +
Sbjct: 1611 ENTKEIVAKMKESQEKEYQFL--------KMTAVNETQEKMCEIEHLKEQFETQKLNLEN 1662
Query: 913 LSINFFSLNKTLHEVLTMCHNASTSVSELNA 943
+ L + LHE L + + +L +
Sbjct: 1663 IETENIRLTQILHENLEEMRSVTKERDDLRS 1693
Score = 52.8 bits (125), Expect = 2e-06
Identities = 116/607 (19%), Positives = 250/607 (41%), Gaps = 97/607 (15%)
Query: 365 EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSE------ 418
++K +E + K +++ ++ + E K Q D+++ + F ++ L+
Sbjct: 652 KEKMKELATTYKQMEN---DIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKV 708
Query: 419 --------DLESTRQIIQK-VNESVV-SIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQ 468
+LE +QK +N+ V + A +++ +L+ E + +++ LR I + +
Sbjct: 709 PKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSE 768
Query: 469 EM---TLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQ 525
E+ T +K E+ K++ ++G LE+ + KT L ST+Q
Sbjct: 769 ELHIITSEKDKLFSEVVHKESRVQGLLEE-----------IGKTKDDLATTQSNYKSTDQ 817
Query: 526 VSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEK 585
+ +Y L EN ++ + ++ + ++ +S + L L +
Sbjct: 818 EFQNFKTLHMDFEQ----KYKMVLEEN-ERMNQEIVNLSKEAQKFDSSLGALKTELSYKT 872
Query: 586 ESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYD 645
+ L+ + ++ + N+ + QLK+ EN QT+ + K+ + E++ LT +
Sbjct: 873 QELQEKTREVQERL-NEME-QLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQE 930
Query: 646 MEILQPLLEQGASLRQTM-------------TYEQPKEAIVIRKKIENLTSAVNSLNFII 692
+ L+ L E R + T EQ + A+ K+ + + + S I
Sbjct: 931 KDDLKQLQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSK--IS 988
Query: 693 KELTKRHNLLRNEVQGRDDALERRI---NEYALEMEDGLNKTMTIINNAI--------DF 741
+E+++ ++ N + +D+ ++ + + LE ++ T + +N I
Sbjct: 989 EEVSRNLHMEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSL 1048
Query: 742 IQDNYALKETL-STIKDNSEIHHKCTSDMETILTFIPQFHRLNDSI---QTLVNDNQRYN 797
IQ+ L++ L S I + ++ ++E + + L D + Q +V + +
Sbjct: 1049 IQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHA 1108
Query: 798 F-----VLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTT 852
+ + LA + +EKL + + Q E Q+ Q+ MS +++K+
Sbjct: 1109 IKKEGELSRTCDRLAEV--EEKLKEKS-----QQLQEKQQQLLNVQEEMSEMQKKINEIE 1161
Query: 853 KIS---KNFETRLQDIES---KVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKAL 906
+ KN E L+ +E+ ++ Q L Y VK +T ER +LQ K+
Sbjct: 1162 NLKNELKNKELTLEHMETERLELAQKLNENYEEVKS---ITKERKVLKELQ------KSF 1212
Query: 907 EAKSIHL 913
E + HL
Sbjct: 1213 ETERDHL 1219
>gi|50511941 EMI domain containing 1 [Homo sapiens]
Length = 443
Score = 67.4 bits (163), Expect = 8e-11
Identities = 41/132 (31%), Positives = 66/132 (50%), Gaps = 7/132 (5%)
Query: 208 KNWCAYVHTRLSPTVILDNQVTYVPGGKGPCGWTGGSCPQRSQK-ISNPVYRMQHKIVTS 266
+NWC+YV TR + + TY+ C W SCP S + + P Y++ +KIVT+
Sbjct: 34 RNWCSYVVTRTISCHVQNG--TYLQRVLQNCPWPM-SCPGSSYRTVVRPTYKVMYKIVTA 90
Query: 267 LDWRCCPGYSGPKCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTD 326
+WRCCPG+SG C+ A SL S + + R GC + + ++T+
Sbjct: 91 REWRCCPGHSGVSCEEVAASSASL---EPMWSGSTMRRMALRPTAFSGCLNCSKVSELTE 147
Query: 327 QVNYQAMKLTLL 338
++ K+T+L
Sbjct: 148 RLKVLEAKMTML 159
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 65.1 bits (157), Expect = 4e-10
Identities = 148/709 (20%), Positives = 294/709 (41%), Gaps = 98/709 (13%)
Query: 365 EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLS------- 417
+DK FQ+ ++ + K++ L D+ + + + +++ E + K LS
Sbjct: 658 KDKEIIFQAHIEEMNEKTLEKL--DVKQTELESLSSELSEVLKARHKLEEELSVLKDQTD 715
Query: 418 ---EDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTC 474
++LE+ + ++ V ++ V +Q L D + ++ R +
Sbjct: 716 KMKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEH 775
Query: 475 EKPIKELEVKQTHLEGALEQ--------------EHSRSILYYESLNKTLSKLKEVH-EQ 519
+ ++ LE EG L+Q H ++ Y E L + KL ++ E+
Sbjct: 776 QAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETER 835
Query: 520 LLSTEQVSD---QKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDL-HIQESKIN 575
+L T+QV++ QK E ++ + + L + ++KQ+ M Q + L + ESK+
Sbjct: 836 ILLTKQVAEVEAQKKDVCTELDAHKI--QVQDLMQQLEKQNSEMEQKVKSLTQVYESKLE 893
Query: 576 NLTVSLEMEKESLRGECEDMLSKCRNDFKFQ-------LKDTEENLHVLNQTLAEVLFPM 628
+ E K+ L E E+M+ + R K + L E+++H+LN+
Sbjct: 894 DGNKEQEQTKQIL-VEKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQ 952
Query: 629 DNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQ----TMTYEQPKEAIVIRKKIE----- 679
+ KM+K+ ++ ++ ++ + LL+Q A L++ T KE K +E
Sbjct: 953 EKKMEKVKQKAKEMQETLK--KKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQAN 1010
Query: 680 --NLTSAVNSLNFIIKE----LTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMT 733
++ AV+ L KE LT+ H R E+ E+++N+ A E+++ +
Sbjct: 1011 SAGISDAVSRLETNQKEQIESLTEVH---RRELNDVISIWEKKLNQQAEELQEIHEIQLQ 1067
Query: 734 IINNAIDFIQDNYAL----KETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTL 789
+ ++ L KE ++ K+ + + + T+ Q + + + +L
Sbjct: 1068 EKEQEVAELKQKILLFGCEKEEMN--KEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSL 1125
Query: 790 VNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLL 849
D + L+ + + ++ L ++ F + + E + ++ +S L KL
Sbjct: 1126 AQDETKLKAHLEKLE----VDLNKSLKENTF--LQEQLVELKMLAEEDKRKVSELTSKLK 1179
Query: 850 LTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKA-LEA 908
T + F++ L+ K ++L + KK S + A+QL + + +A LEA
Sbjct: 1180 TT---DEEFQS-LKSSHEKSNKSLEDKSLEFKKLS-----EELAIQLDICCKKTEALLEA 1230
Query: 909 KSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQKGLTEFVE 968
K+ L S + ++ C + +T V E A + K S + QL Q LTE +
Sbjct: 1231 KTNELINISSSKTNAILSRISHCQHRTTKVKE--ALLIKTCTVSELEAQLRQ--LTE-EQ 1285
Query: 969 PIIQIKTQAALSNLTCCIDRSLPGSLANVVKSQK-QVKSLPKKINALKK 1016
+ I Q A L N +KS K ++SL + AL+K
Sbjct: 1286 NTLNISFQQATHQLE---------EKENQIKSMKADIESLVTEKEALQK 1325
Score = 60.8 bits (146), Expect = 7e-09
Identities = 114/606 (18%), Positives = 234/606 (38%), Gaps = 86/606 (14%)
Query: 321 MQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKS 380
++K+ +N + T LQ+++ + + + + S L K+ + EFQSL K
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL-KTTDEEFQSL-KSSHE 1193
Query: 381 KSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQ 440
KS N E + FK LSE+L I K E+++
Sbjct: 1194 KS-----------------NKSLEDKSLEFK---KLSEELAIQLDICCKKTEALLEAKTN 1233
Query: 441 QKF-VLVQENRPTLTDIVELRNHIVNVRQEMTL-TCEKPIKELEVKQTHLEGALEQEHSR 498
+ + + L+ I ++ V++ + + TC + ELE + L E++++
Sbjct: 1234 ELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCT--VSELEAQLRQLT---EEQNTL 1288
Query: 499 SILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNA---------PAAESVSNNVTEYMSTL 549
+I + ++ ++ K ++ E + +K A AA + +T+ L
Sbjct: 1289 NISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKEL 1348
Query: 550 HENIKKQSLMMLQMFEDLHIQESKINNLT-VSLEMEKESLRGECEDMLSKCRNDFKFQLK 608
ENI +LM ++ E S LT ++++++ E E +S R +
Sbjct: 1349 SENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYD---- 1404
Query: 609 DTEENLHVLNQTLAEVLFPMDN-KMDKMS--EQLNDLTYDMEILQPLLEQGASLRQTMTY 665
EE +L+Q + ++ F +D +K+S EQ++D + + + + Q
Sbjct: 1405 --EEKCELLDQ-VQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVK 1461
Query: 666 EQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEYALEME 725
E + + K+ +N L + + KR + L+ E++ +E++ + E++
Sbjct: 1462 ELQIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 726 DGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHK-------------------CT 766
+ M + ++ + +L E L +I HK
Sbjct: 1522 SQTARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVK 1581
Query: 767 SDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVL----------------QVAKTLAGIP 810
E ILT Q + + ++T + + N + + A LA +
Sbjct: 1582 EAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELK 1641
Query: 811 R--DEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESK 868
R ++K+ Q + QM + + + ++S L KL + E +L+ +ES
Sbjct: 1642 RKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQEREREVHILEEKLKSVESS 1701
Query: 869 VTQTLI 874
++TLI
Sbjct: 1702 QSETLI 1707
Score = 44.7 bits (104), Expect = 6e-04
Identities = 82/406 (20%), Positives = 168/406 (41%), Gaps = 45/406 (11%)
Query: 282 LRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKK 341
+ + + ++LI A++ A E+ QGC +K++ K LLQ+
Sbjct: 1698 VESSQSETLIVPRSAKNVAAYTE--QEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRV 1755
Query: 342 IDNISLTVN---DVRNTYSSLEGKV--SEDKSREFQSLLKGL------KSKSINVLIRDI 390
TV+ ++R Y K+ +E K E QS++ L K+K ++++
Sbjct: 1756 GQEKEETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQH 1815
Query: 391 VREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENR 450
V ++ ++ + +F V ++ E T QI+++ + + S +QK V E
Sbjct: 1816 VEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIKELDSCLVRQKEVHRVEME 1875
Query: 451 PTLTDIVEL--------RNHIVNVRQEMT-------LTCEKPIKELEVKQTHLEGAL--- 492
+ +L RN + +E T L K + +E + LE L
Sbjct: 1876 ELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKLLSNMEAQHNDLEFKLAGA 1935
Query: 493 EQEHSRSILYYESLNKTLSKLKEVHEQLLS--TEQVSDQKNAPAAESVSNNVTEYMSTLH 550
E+E + L K L L++ H+Q L ++ ++ + + ++ STL
Sbjct: 1936 EREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQEREEKIKQEQEDLELKHNSTLK 1995
Query: 551 ENIKKQSLMMLQMFEDLHIQESKINNLTVSLEME-KESLRGECEDMLSKCRNDFKFQLKD 609
+ +++ + + Q ++L + + N +E E ES + E +L K + +
Sbjct: 1996 QLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEETNQLLKK--------IAE 2047
Query: 610 TEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQ 655
+++L + E+L D + ++M+ ++ DL +E LQ +Q
Sbjct: 2048 KDDDLKRTAKRYEEIL---DAREEEMTAKVRDLQTQLEELQKKYQQ 2090
Score = 42.0 bits (97), Expect = 0.004
Identities = 119/648 (18%), Positives = 256/648 (39%), Gaps = 73/648 (11%)
Query: 411 KTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEM 470
KT+ +L + ++ ++++ E++ S +Q +L E + E + ++
Sbjct: 279 KTLETLQQRVKRQENLLKRCKETIQS-HKEQCTLLTSEKEALQEQLDERLQELEKIKDLH 337
Query: 471 TLTCEKPIKELEVKQTHLEGALEQEHSRSILYYE-SLNKTLSKLKEVHEQLLST------ 523
K I +L + +E LEQ+ I + +++TL +E QL S
Sbjct: 338 MAEKTKLITQLRDAKNLIE-QLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTT 396
Query: 524 --EQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSL 581
E++ +QK + + + + +ST + + + + +M E + E +SL
Sbjct: 397 QGEELREQKEK-SERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISL 455
Query: 582 EMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLND 641
+ E ++ E D++ K + +L+ E L + E+ + + + EQ+
Sbjct: 456 QQELSRVKQEVVDVMKKSSEEQIAKLQKLHEK--ELARKEQELTKKLQTREREFQEQMKV 513
Query: 642 LTYDMEILQPLLEQGASLRQTMTYEQ---PKEAIVI--RKKIENLTSAVNSLNFIIKEL- 695
+ + Q ++++ E+ K+AI+ K+ +L + I EL
Sbjct: 514 ALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELE 573
Query: 696 -TKRHNLLRNEVQGRDDA--LERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETL 752
+ +L N+ Q +D A LE N++ E+ + K T + + Q + E L
Sbjct: 574 SSLEKSLQENKNQSKDLAVHLEAEKNKHNKEITVMVEKHKTELESLKH--QQDALWTEKL 631
Query: 753 STIK-----DNSEIHHKCTSDMETIL-----TFIPQFHRLNDSIQTLVNDNQRYNFVLQV 802
+K + ++ KC + ET+L F +N+
Sbjct: 632 QVLKQQYQTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNE------------------ 673
Query: 803 AKTLAGIPRDEKLN--QSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFET 860
KTL EKL+ Q+ + + +E K ++ +S L+++ T K+ + E
Sbjct: 674 -KTL------EKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQ---TDKMKQELEA 723
Query: 861 RLQD----IESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSIN 916
++ + + +V + + +S+++ ++ L+L +L R K L+ H+
Sbjct: 724 KMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLEL-LLKERDKHLKEHQAHVENL 782
Query: 917 FFSLNKTLHEVLTMCHNASTSVSELNATIPKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQ 976
+ ++ E+ S +AT + + QL QK L E I+ K
Sbjct: 783 EADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQV 842
Query: 977 AALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVNLTTV 1024
A + + L A+ ++ Q ++ L K+ + +++ +LT V
Sbjct: 843 AEVEAQKKDVCTELD---AHKIQVQDLMQQLEKQNSEMEQKVKSLTQV 887
>gi|62243484 sarcoma antigen NY-SAR-41 [Homo sapiens]
Length = 1417
Score = 63.5 bits (153), Expect = 1e-09
Identities = 117/615 (19%), Positives = 247/615 (40%), Gaps = 80/615 (13%)
Query: 285 QEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDN 344
Q QSLI N ++ + + E + G +V + + DQ + K +K+
Sbjct: 584 QLSQSLITCNDSQESSKLSSLETEPVK---LGGHQVAESVKDQNQHTMNKQ--YEKERQR 638
Query: 345 ISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQE 404
+ + ++R +E + S+ K +N+ R QF++ Q ++ E
Sbjct: 639 LVTGIEELRTKLIQIEAENSDLK---------------VNMAHRT---SQFQLIQEELLE 680
Query: 405 TVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIA--AQQKFVLVQENRPTLTDIVELRNH 462
+ K S +++ + +++ E +V+ + A + L QE I L +
Sbjct: 681 KASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETN 740
Query: 463 IVNVRQEMTLTCEKPIK-------ELEVKQTHLEGALEQEHSRSILYYESLNKTLSKL-- 513
I +++ L EK K E+E + LE LE++ + ++ KT+S L
Sbjct: 741 INTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQ----FKEQEKTMSMLQQ 796
Query: 514 ----KEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHI 569
K+ H + L +++ K E++ + E + L + ++++ + Q+ L I
Sbjct: 797 DIICKQHHLESLD-RLLTESKGEMKKENMKKD--EALKALQNQVSEETIKVRQLDSALEI 853
Query: 570 QESKI----NNLTVSLEMEKESLRGECEDM--LSKCRNDFKFQLKDTEENLHVLNQTLAE 623
+ ++ N L + E ++ L+ + E++ L K L++T E +L TL +
Sbjct: 854 CKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQ 913
Query: 624 VLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGAS-LRQTMTYEQPKEAIVIRKKIENLT 682
+M +Q ++E Q LE+ S L Q + ++ A +RK E
Sbjct: 914 --------QQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCE 965
Query: 683 SAVNSLNFI---IKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAI 739
SA + + + ELT ++ E+ + L + E DG NK M + +
Sbjct: 966 SAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDM 1025
Query: 740 DFIQDNYALKETLSTIKDNSEIHHKCTSDMETIL----TFIPQFHRLNDSIQTLVNDNQR 795
Q L++ + +K+ ++ H +++ L + + +++ + Q
Sbjct: 1026 ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQE 1085
Query: 796 YNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKIS 855
VLQ A Q + ++ Y + T+++R+ + + +++LL +
Sbjct: 1086 LRDVLQKA-------------QLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQAL 1132
Query: 856 KNFETRLQDIESKVT 870
K L+ ++VT
Sbjct: 1133 KERNWELKQRAAQVT 1147
Score = 48.1 bits (113), Expect = 5e-05
Identities = 93/504 (18%), Positives = 211/504 (41%), Gaps = 83/504 (16%)
Query: 281 QLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQ---QGCGDPEVMQKMTDQVNYQAMKLTL 337
Q + +Q+++ + ++ T + + V++ +Q+ Q E ++KM ++ A + L
Sbjct: 914 QQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADL 973
Query: 338 LQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI 397
++K+ ++ T V+ + ++S+ +E L + ++K++++ D++ +Q K
Sbjct: 974 KRQKVIELTGTARQVKIEMDQYKEELSK-MEKEIMHLKRDGENKAMHLSQLDMILDQTKT 1032
Query: 398 FQNDMQETVAQLFK----TVSSLSE-----------------DLESTRQIIQKVNESV-- 434
V +L K T + L+E +L+ST + +Q++ + +
Sbjct: 1033 ELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQK 1092
Query: 435 VSIAAQQKFVLVQ----ENRPTLTDIVELRNHIVNVRQ-----------------EMTLT 473
++ ++K+ ++ E R +I + + ++ + Q + +T
Sbjct: 1093 AQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMT 1152
Query: 474 CEKPIKELEVKQTHLEGALEQ---EHSRSILYYESLNKTLSKLKEVHEQ-----LLSTEQ 525
+ E+E K LEG LE+ E ESLN L KE + L + ++
Sbjct: 1153 IREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQE 1212
Query: 526 VSD--------QKNAPAAESVSNNVTEYMSTLHE---NIKKQSLMMLQMFEDLHIQESKI 574
+S Q+ ESV +Y++T ++ ++ ++ + + ++ H + ++
Sbjct: 1213 ISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEA 1272
Query: 575 NNLTVSLEMEKESLRGECEDM--LSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKM 632
+ V + E E L E EDM LSK ++ L E L A + M ++
Sbjct: 1273 RHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHL---AEELGASKVREAHLEARMQAEI 1329
Query: 633 DKMSEQLNDL--TYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNF 690
K+S ++ L Y ME++ Q + ++ + K + ++ L +
Sbjct: 1330 KKLSAEVESLKEAYHMEMIS---HQENHAKWKISADSQKSS------VQQLNEQLEKAKL 1380
Query: 691 IIKELTKRHNLLRNEVQGRDDALE 714
++E + L +VQ R++ +E
Sbjct: 1381 ELEEAQDTVSNLHQQVQDRNEVIE 1404
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 62.0 bits (149), Expect = 3e-09
Identities = 104/497 (20%), Positives = 201/497 (40%), Gaps = 51/497 (10%)
Query: 317 DPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVR---NTYSSLEGKVSEDKSREFQS 373
+P+ ++++ D+ M+L K+ ++ + + N S G +S K REF S
Sbjct: 274 EPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSF-KLREFAS 332
Query: 374 LLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSED---LESTRQIIQKV 430
L+ L+ + ++ E K Q + E AQL K +S+ +D LE +I+Q
Sbjct: 333 HLQQLQDA-----LNELTEEHSKATQ-EWLEKQAQLEKELSAALQDKKCLEEKNEILQGK 386
Query: 431 NESVVSIAAQQKFVLVQENRPTLTDIVELR------------NHIVNVRQEMTLTCEKPI 478
+ +Q + QE L D+++L N + R EM E
Sbjct: 387 LSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEML---ETER 443
Query: 479 KELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESV 538
+ E K G E+E + L ++S L + E+L EQ S A V
Sbjct: 444 GQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEEL---EQASQAHGARLTAQV 500
Query: 539 SNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSK 598
+ ++T ++TL+ I++Q + + + +++++ E + LR + E + S
Sbjct: 501 A-SLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSS 559
Query: 599 CRNDFKFQLKDTEENLHVLNQ-------TLAEVLFPMDNKMDKMSEQLNDLTYD----ME 647
+ + QLK+ E Q T AE + D +QL L + +E
Sbjct: 560 LKQK-EQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLE 618
Query: 648 ILQPLLEQGASLR---QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRN 704
ILQ L+ R QT + +E + +K+E L + V + ++ + +
Sbjct: 619 ILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETAR--QEQHEAQAQVAEL 676
Query: 705 EVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHK 764
E+Q R + + E + +D L + + + ++ + +L+E D E +
Sbjct: 677 ELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKG--SLEEEKRRAADALEEQQR 734
Query: 765 CTSDMETILTFIPQFHR 781
C S+++ + + H+
Sbjct: 735 CISELKAETRSLVEQHK 751
Score = 46.6 bits (109), Expect = 1e-04
Identities = 111/588 (18%), Positives = 221/588 (37%), Gaps = 75/588 (12%)
Query: 294 NQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVR 353
+Q E H + + Q++ + GD ++ + + A T LQ +++ +
Sbjct: 388 SQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQE 447
Query: 354 NTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTV 413
+ G E+K ++ SL+ L+S N+ EQ Q A+L V
Sbjct: 448 AKLLAERGHFEEEK-QQLSSLITDLQSSISNLSQAKEELEQAS------QAHGARLTAQV 500
Query: 414 SSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT 473
+SL+ +L + IQ+ ++ + + Q K E
Sbjct: 501 ASLTSELTTLNATIQQQDQELAGLKQQAK--------------------------EKQAQ 534
Query: 474 CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAP 533
+ +++ E L +EQ S SL + +LKEV E+ +T Q Q+ A
Sbjct: 535 LAQTLQQQEQASQGLRHQVEQLSS-------SLKQKEQQLKEVAEKQEATRQDHAQQLAT 587
Query: 534 AAESVSNNVTEYMSTLH--ENIKKQSLMMLQMFED-LHIQESKINNLTVSL---EMEKES 587
AAE ++ E + L E ++K+ L++ + L + ++ S+ + EK
Sbjct: 588 AAEEREASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAE 647
Query: 588 LRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQ---LNDLTY 644
L + E+ L C ++ + H +AE+ + ++ K +E+ +
Sbjct: 648 LSRKVEE-LQAC-------VETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQ 699
Query: 645 DMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRN 704
E LQ L E + ++ E+ + A + ++ ++ ++++ + L
Sbjct: 700 LQEQLQALKESLKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEE 759
Query: 705 EVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHK 764
E GR LE R+ + + + A+ + A E +K+ + +
Sbjct: 760 ERAGRK-GLEARLQQLGEAHQAETEVLRRELAEAM--AAQHTAESECEQLVKEVAAWRER 816
Query: 765 CTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKT-LAGIPRDEKLNQS----- 818
+ + F + + TL + ++ LQ AK +AGI +L S
Sbjct: 817 YEDSQQEEAQYGAMFQ---EQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNE 873
Query: 819 ------NFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFET 860
N + Q E + +K ++S L+EK+ T+K ET
Sbjct: 874 LAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLET 921
Score = 39.7 bits (91), Expect = 0.018
Identities = 85/452 (18%), Positives = 178/452 (39%), Gaps = 40/452 (8%)
Query: 279 KCQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLL 338
+CQ + ++ SL + +AE + R A + Q +++ ++ + L
Sbjct: 1135 QCQKQQEQADSLERSLEAERASRAERDSALETLQGQ------LEEKAQELGHSQSALASA 1188
Query: 339 QKKIDNISLTVNDVRNTYSSLEGKVSEDK--SREFQSLLKGLKSKSINVLIRDIVREQFK 396
Q+++ V D + +V+ + + SL+ L+ + +++L R ++ ++ +
Sbjct: 1189 QRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEE-VSILNRQVLEKEGE 1247
Query: 397 IFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDI 456
+ + +L S S+ LE +++Q S + AA++ L +E + +
Sbjct: 1248 ------SKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEA 1301
Query: 457 VELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEV 516
+ R N+RQE+T E+ + + + E ++E + S L E + + +
Sbjct: 1302 EKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEH-----TSTQAL 1356
Query: 517 HEQLLSTEQVSDQKNA--PAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKI 574
+LL + + Q A AAE E ++ + L + +L K+
Sbjct: 1357 VSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKV 1416
Query: 575 ---NNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNK 631
L EK S E ML K + + E ++ Q L +D
Sbjct: 1417 AEQERTAQQLRAEKASY-AEQLSMLKKAHGLLAEENRGLGERANLGRQFLE---VELDQA 1472
Query: 632 MDKMSEQLNDLTYDME--ILQPLLEQGASLRQ----TMTYEQPKEAIV-----IRKKIEN 680
+K ++L + D E + + E ++ R+ T YE K ++ +++ +
Sbjct: 1473 REKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQK 1532
Query: 681 LTSAVNSLNFIIKELTKRHNLLRNEVQGRDDA 712
LT+ V L +E TK+ L ++ D A
Sbjct: 1533 LTAQVEQLEVFQREQTKQVEELSKKLADSDQA 1564
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 60.5 bits (145), Expect = 1e-08
Identities = 90/439 (20%), Positives = 174/439 (39%), Gaps = 67/439 (15%)
Query: 319 EVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSR------EFQ 372
E Q+ + + +LQ ++ ++ V + N + + K S+ E
Sbjct: 2424 EKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNLSSQVECLELEKA 2483
Query: 373 SLLKGLKS---------KSINVLIRDIVREQFKIFQND-----MQETVAQLFKTVSSLSE 418
LL+GL S+N LI+++ + K+ + D ++ + + VS LS+
Sbjct: 2484 QLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQEQLVSKLSQ 2543
Query: 419 DLESTRQIIQKVNESV--VSIAAQQKFVLVQENRPTLTDIVE-LRNHIVNVRQEMTLT-- 473
+E Q+ ++ N + +++ +QK ++Q +L D +E L++ N+ E+ LT
Sbjct: 2544 -VEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKM 2602
Query: 474 ------------------CEKPIKELEVKQTHLEGALEQEHSRSI----LYYESLNKTLS 511
++ + E+ K L+ L E +R L E + +
Sbjct: 2603 DKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662
Query: 512 KLKEV---HEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLH 568
+LKE+ + +L + + V + EY LHE KK ++L +
Sbjct: 2663 QLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE 2722
Query: 569 IQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPM 628
++ S E S + E D+L + + LK T + L L +T + L +
Sbjct: 2723 VEIQTYREKLTSKEECLSSQKLEI-DLLKSSKEELNNSLKATTQILEELKKTKMDNLKYV 2781
Query: 629 D----------NKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKI 678
+ KM + + L + EILQ L Q + + E+ K V+ K+
Sbjct: 2782 NQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAAQ-----EKQKTGTVMDTKV 2836
Query: 679 ENLTSAVNSLNFIIKELTK 697
+ LT+ + L ++E TK
Sbjct: 2837 DELTTEIKELKETLEEKTK 2855
Score = 58.9 bits (141), Expect = 3e-08
Identities = 132/669 (19%), Positives = 270/669 (40%), Gaps = 116/669 (17%)
Query: 293 TNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDNISLTVNDV 352
T + ESH + + + + E++Q ++ V+ T LQ+K+ ++ +
Sbjct: 1988 TQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQAL 2047
Query: 353 RNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKT 412
T LE ++++ ++E + L+K +S+S+ + + E+ + ++ + + +
Sbjct: 2048 SLTKCELENQIAQ-LNKEKELLVK--ESESLQARLSESDYEKLNV-SKALEAALVEKGEF 2103
Query: 413 VSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLV--------QENRPTLTDIVELRNHIV 464
LS E Q+ + + + V I A +K L + +L D VE +
Sbjct: 2104 ALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERENDSLKDKVENLEREL 2163
Query: 465 NVRQE----MTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYE---------------S 505
+ +E + L E E+E +T +E E +RS+ +E
Sbjct: 2164 QMSEENQELVILDAENSKAEVETLKTQIE-----EMARSLKVFELDLVTLRSEKENLTKQ 2218
Query: 506 LNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFE 565
+ + +L E+ + L S + + ++K + + T + L +K+ + + +
Sbjct: 2219 IQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTA-VEMLQNQLKELNEAVAALCG 2277
Query: 566 DLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVL 625
D I ++ +L +E E+ LR E + ++ D K QL VL Q L
Sbjct: 2278 DQEIMKATEQSLDPPIE-EEHQLRNSIEKLRARLEADEKKQLC-------VLQQ-----L 2324
Query: 626 FPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPK-EAIVIRKKIENLTSA 684
++ D + ++ +L ++EI + E A + E K E ++ KIE +T +
Sbjct: 2325 KESEHHADLLKGRVENLERELEIARTNQEHAA-----LEAENSKGEVETLKAKIEGMTQS 2379
Query: 685 VNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQD 744
+ L + + L NE+Q + RI+E + IIN++ + I
Sbjct: 2380 LRGLELDVVTIRSEKENLTNELQKE----QERISE------------LEIINSSFENILQ 2423
Query: 745 NYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYN------- 797
KE ++ ++ K ++ ME + T Q LN+ + L ND +
Sbjct: 2424 E---KE-----QEKVQMKEKSSTAMEMLQT---QLKELNERVAALHNDQEACKAKEQNLS 2472
Query: 798 -----FVLQVAKTLAGIPRDEKLN-----QSNFQKMYQMFNETTSQVRKYQQNMSHLEEK 847
L+ A+ L G+ DE N QS+ + Q + ++ K + +S L+ +
Sbjct: 2473 SQVECLELEKAQLLQGL--DEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQ 2530
Query: 848 LLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQ---------LQV 898
+ + + ++L +E + Q + ++ +V ++ Q LQ L+V
Sbjct: 2531 I----QDQEQLVSKLSQVEGE-HQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEV 2585
Query: 899 LNSRFKALE 907
L S +K LE
Sbjct: 2586 LQSSYKNLE 2594
Score = 58.2 bits (139), Expect = 5e-08
Identities = 125/666 (18%), Positives = 265/666 (39%), Gaps = 91/666 (13%)
Query: 323 KMTDQVNYQAMKLTLLQKKI----DNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGL 378
+ T Q + + K T L++K+ +++S + + SLE K+ E K +EFQ L
Sbjct: 345 RTTAQYDQASTKYTALEQKLKKLTEDLSCQRQNAESARCSLEQKIKE-KEKEFQEELSR- 402
Query: 379 KSKSINVLIRDIVR---------EQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQ- 428
+ +S L ++ ++ +Q K N +Q + +L L +LE +Q +
Sbjct: 403 QQRSFQTLDQECIQMKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCR 462
Query: 429 ----------KVNESVVSIAAQQKF--VLVQENRPTLTDIVELRNHIVNVRQEMTLTCEK 476
K NE S+ +K +L + ++ L + N++Q + + +
Sbjct: 463 AEQAFQASQIKENELRRSMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQS-QN 521
Query: 477 PIKELEVKQTHLEGAL--------EQEHSRSILYYESLNKTLSKLKEVHEQLLST----- 523
+E++ K T E L +QE+S ++ + L K ++ + LL
Sbjct: 522 FAEEMKAKNTSQETMLRDLQEKINQQENSLTLEKLKLAVADLEKQRDCSQDLLKKREHHI 581
Query: 524 EQVSDQKNAPAAESVSN-NVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLE 582
EQ++D+ + ES + + E +E +K++ + +S+ L +E
Sbjct: 582 EQLNDKLSKTEKESKALLSALELKKKEYEELKEEKTLF-------SCWKSENEKLLTQME 634
Query: 583 MEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLN---QTLAEVLFPMDNKMDKMSEQL 639
EKE+L+ + L C + + + E + L + L+ + + N +D S ++
Sbjct: 635 SEKENLQSKINH-LETCLKTQQIKSHEYNERVRTLEMDRENLSVEIRNLHNVLDSKSVEV 693
Query: 640 NDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRH 699
T + ++ L+Q + K +K+IEN+ + L +++L +
Sbjct: 694 E--TQKLAYME--------LQQKAEFSDQKH----QKEIENMCLKTSQLTGQVEDLEHKL 739
Query: 700 NLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNS 759
LL NE+ +D + EY + +K +++ N +D+ + +L
Sbjct: 740 QLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASLVTN-----EDH---QRSLLAFDQQP 791
Query: 760 EIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSN 819
+HH + I+ + + + + + +LQ R + L S
Sbjct: 792 AMHHSFAN----IIGEQGSMPSERSECRLEADQSPKNSAILQ--------NRVDSLEFS- 838
Query: 820 FQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYIS 879
+ QM ++ Q + Q +EE L+ ++ ++F SK+ + +
Sbjct: 839 LESQKQMNSDLQKQCEELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNV 898
Query: 880 VKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVS 939
V + +++ LQL LN + + +A+ L + L +L E+ + S
Sbjct: 899 VAETLSALENKEKELQL--LNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKK 956
Query: 940 ELNATI 945
E+++ I
Sbjct: 957 EMSSII 962
Score = 52.0 bits (123), Expect = 3e-06
Identities = 147/756 (19%), Positives = 305/756 (40%), Gaps = 127/756 (16%)
Query: 280 CQLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTL-- 337
C L A+ + NQ+++ AE+ + + +++ + +++N Q LTL
Sbjct: 503 CHLEAELKNIKQCLNQSQNF-------AEEMKAKNTSQETMLRDLQEKINQQENSLTLEK 555
Query: 338 -------LQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDI 390
L+K+ D + + L K+S+ + +E ++LL L+ K
Sbjct: 556 LKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTE-KESKALLSALELKKKEYEELKE 614
Query: 391 VREQFKIFQNDMQETVAQLFKTVSSLSEDLE------STRQI-IQKVNESVVSIAAQQKF 443
+ F ++++ ++ + Q+ +L + T+QI + NE V ++ ++
Sbjct: 615 EKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDREN 674
Query: 444 VLVQ-ENRPTLTD--IVELRNH---IVNVRQEMTLTCEKPIKELE---VKQTHLEGALEQ 494
+ V+ N + D VE+ + ++Q+ + +K KE+E +K + L G +E
Sbjct: 675 LSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQVED 734
Query: 495 -EHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNA------------------PAA 535
EH +L E ++K +++H + S + K+A PA
Sbjct: 735 LEHKLQLLSNEIMDKDRC-YQDLHAEYESLRDLLKSKDASLVTNEDHQRSLLAFDQQPAM 793
Query: 536 ESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKE--------- 586
N+ ++ + L Q ++ I ++++++L SLE +K+
Sbjct: 794 HHSFANIIGEQGSMPSERSECRLEADQSPKNSAILQNRVDSLEFSLESQKQMNSDLQKQC 853
Query: 587 ----SLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQ-------TLAEVLFPMDNKMDKM 635
++GE E+ L K + + +T + + L + +AE L ++NK +K
Sbjct: 854 EELVQIKGEIEENLMKAEQMHQSFVAETSQRISKLQEDTSAHQNVVAETLSALENK-EKE 912
Query: 636 SEQLND-----------LTYDMEILQPLLEQGASLRQTMTYEQPKEAIVI---RKKIENL 681
+ LND L +L+ L++ L +T++ E+ + + +I +++IE L
Sbjct: 913 LQLLNDKVETEQAEIQELKKSNHLLEDSLKELQLLSETLSLEKKEMSSIISLNKREIEEL 972
Query: 682 TSAVNSLNFIIKELT-KRHNLLR------NEVQGRDDALERRINEYALEMEDGLNKTMTI 734
T +L I L ++ NL++ N + R+ ++ ++Y E L +
Sbjct: 973 TQENGTLKEINASLNQEKMNLIQKSESFANYIDEREKSISELSDQYKQEKLILLQRCEET 1032
Query: 735 INNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQ----FHRLNDSIQTLV 790
N D Q A +E S ++ + ++CTS E + Q F + + T +
Sbjct: 1033 GNAYEDLSQKYKAAQEKNSKLEC---LLNECTSLCENRKNELEQLKEAFAKEHQEFLTKL 1089
Query: 791 --NDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQK----MYQMFNETTSQVRKYQQNMSHL 844
+ + N +L++ + + NQ+N + + Q + K Q+ ++ L
Sbjct: 1090 AFAEERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDL 1149
Query: 845 EEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFK 904
++ K+ K + Q++ES+ P SVK+ N+ + Q+
Sbjct: 1150 LQENEQLMKVMKT-KHECQNLESE------PIRNSVKERESERNQCNFKPQMD------- 1195
Query: 905 ALEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSE 940
LE K I L S N L ++ M N + E
Sbjct: 1196 -LEVKEISLD----SYNAQLVQLEAMLRNKELKLQE 1226
Score = 47.4 bits (111), Expect = 9e-05
Identities = 114/574 (19%), Positives = 228/574 (39%), Gaps = 108/574 (18%)
Query: 337 LLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFK 396
+LQ ++D++ ++ + S L+ + E V I+ + E
Sbjct: 827 ILQNRVDSLEFSLESQKQMNSDLQKQCEE------------------LVQIKGEIEENLM 868
Query: 397 IFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDI 456
+ Q VA+ + +S L ED + + ++ E++ ++ ++K + + L D
Sbjct: 869 KAEQMHQSFVAETSQRISKLQEDTSAHQNVVA---ETLSALENKEKELQL------LNDK 919
Query: 457 VELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYY-----ESLNKTLS 511
VE + ++ E +KEL++ L +LE++ SI+ E L +
Sbjct: 920 VETEQAEIQELKKSNHLLEDSLKELQLLSETL--SLEKKEMSSIISLNKREIEELTQENG 977
Query: 512 KLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEY---MSTLHENIKKQSLMMLQM----- 563
LKE++ L + QK+ ES +N + E +S L + K++ L++LQ
Sbjct: 978 TLKEINASLNQEKMNLIQKS----ESFANYIDEREKSISELSDQYKQEKLILLQRCEETG 1033
Query: 564 --FEDLHIQ-----------ESKINNLTV-------SLEMEKESLRGECEDMLSKC---- 599
+EDL + E +N T LE KE+ E ++ L+K
Sbjct: 1034 NAYEDLSQKYKAAQEKNSKLECLLNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAE 1093
Query: 600 -RND------------FKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDM 646
RN + ++ D + N L + + + + +KM +++NDL +
Sbjct: 1094 ERNQNLMLELETVQQALRSEMTDNQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQEN 1153
Query: 647 EILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKEL---TKRHNLLR 703
E L +++ Q + E + ++ R+ N + ++ +KE+ + L++
Sbjct: 1154 EQLMKVMKTKHEC-QNLESEPIRNSVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQ 1212
Query: 704 NEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHH 763
E R+ L+ + +E + ++ L + I ++ + +S +KD
Sbjct: 1213 LEAMLRNKELKLQESE---KEKECLQHELQTIRGDLETSNLQDMQSQEISGLKD------ 1263
Query: 764 KCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKM 823
C D E +I H L+ T NDN LQ T+ + EK+ + +
Sbjct: 1264 -CEIDAEE--KYISGPHELS----TSQNDNAHLQCSLQT--TMNKLNELEKICEILQAEK 1314
Query: 824 YQM---FNETTSQVRKYQQNMSHLEEKLLLTTKI 854
Y++ N++ S+ + M+ KLL KI
Sbjct: 1315 YELVTELNDSRSECITATRKMAEEVGKLLNEVKI 1348
Score = 35.4 bits (80), Expect = 0.34
Identities = 129/640 (20%), Positives = 243/640 (37%), Gaps = 92/640 (14%)
Query: 340 KKIDNISLTVNDVRNTYSSLEGKVSED---KSREFQSLLKGLKSKSINVLIRDIVREQFK 396
K ++ + R + LE K+ K++E Q L + L S+ + D +R+Q+
Sbjct: 1547 KGVEELESLCEVYRQSLEKLEEKMESQGIMKNKEIQELEQLLSSERQEL---DCLRKQYL 1603
Query: 397 IFQNDMQETVAQL-FKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTL-- 453
Q+ + + + S L+ + + T Q+ ++ +A Q L +R L
Sbjct: 1604 SENEQWQQKLTSVTLEMESKLAAEKKQTEQLSLELE-----VARLQLQGLDLSSRSLLGI 1658
Query: 454 --TDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLS 511
D ++ RN ++ +E T + + +V Q + A + + L E + +T
Sbjct: 1659 DTEDAIQGRNESCDISKEHTSETTERTPKHDVHQICDKDAQQDLN----LDIEKITET-G 1713
Query: 512 KLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMM--LQMFEDLH- 568
+K E S EQ D P E + +E +S L + + M L ED+H
Sbjct: 1714 AVKPTGE--CSGEQSPDTNYEPPGEDKTQGSSECISELSFSGPNALVPMDFLGNQEDIHN 1771
Query: 569 ----IQESKINNLTVSLEMEK-----ESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQ 619
++E+ NL + +E ESL E +++ SK + QL E L +
Sbjct: 1772 LQLRVKETSNENLRLLHVIEDRDRKVESLLNEMKELDSKLHLQ-EVQLMTKIEACIELEK 1830
Query: 620 TLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIE 679
+ E + + +SE+L + D + L +E L + K + R+ I
Sbjct: 1831 IVGE----LKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLEMHADKSS---REDIG 1883
Query: 680 NLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAI 739
+ + VN +R + NE+ R + + I AL +E L T +
Sbjct: 1884 DNVAKVND------SWKERFLDVENELS-RIRSEKASIEHEALYLEADLEVVQT---EKL 1933
Query: 740 DFIQDN-------YALKETLSTIKDNSEIHHKCTSDMETILTFIPQF-HRLNDSIQTLVN 791
+DN L+E LS + M T + Q ++ + Q L +
Sbjct: 1934 CLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEKMKEKTQELES 1993
Query: 792 DNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLT 851
+QVA ++ ++ ++ +S V + ++ +HL+EKL
Sbjct: 1994 HQSECLHCIQVA-------------EAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSL 2040
Query: 852 TKISKNFETRLQDIESKVTQTLIPYYISVKKGSVVTNERDQALQLQVLNSRF------KA 905
K S+ ++E+++ Q + K + + ++LQ ++ S + KA
Sbjct: 2041 EKDSQALSLTKCELENQIAQ--------LNKEKELLVKESESLQARLSESDYEKLNVSKA 2092
Query: 906 LEAKSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATI 945
LEA + L+ T EV H + +L I
Sbjct: 2093 LEAALVEKGEFALRLSSTQEEV----HQLRRGIEKLRVRI 2128
>gi|157785668 coiled-coil domain containing 39 [Homo sapiens]
Length = 941
Score = 60.1 bits (144), Expect = 1e-08
Identities = 110/588 (18%), Positives = 262/588 (44%), Gaps = 78/588 (13%)
Query: 285 QEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQKKIDN 344
+E+++L+ + +G E +++ D ++++ T +++ ++ L + ++D+
Sbjct: 256 REKENLVKEKIKFLESEIGNNT-EFEKRISVADRKLLKCRTAYQDHETSRIQL-KGELDS 313
Query: 345 ISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLI----RDIVREQFKIFQ- 399
+ TVN + +L +S+ K + + K+K+ N +I ++I + + +
Sbjct: 314 LKATVNRTSSDLEALRKNISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEK 373
Query: 400 -NDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVE 458
++++ + + K V + L + ++ K + + + ++K VL E T + +
Sbjct: 374 ATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQELQTETMKEKAVL-SEIEGTRSSLKH 432
Query: 459 LRNHIVNV------RQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSK 512
L + + + +QE+ + + I+++E + + L+G + E ++L + +
Sbjct: 433 LNHQLQKLDFETLKQQEIMYSQDFHIQQVERRMSRLKGEINSEEK------QALEAKIVE 486
Query: 513 LKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENI-KKQSLMMLQMFEDLHIQE 571
L++ E+ ST + + + + + N++ +N +KQSLM
Sbjct: 487 LRKSLEEKKSTCGLLETQ----IKKLHNDLYFIKKAHSKNSDEKQSLM------------ 530
Query: 572 SKINNLTVSL---EMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPM 628
+KIN L + + E E + +G +D++ + N K ++K T E LH + AE + +
Sbjct: 531 TKINELNLFIDRSEKELDKAKGFKQDLMIE-DNLLKLEVKRTREMLH----SKAEEVLSL 585
Query: 629 DNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIR-----KKIENLTS 683
+ + ++ + + T ++++ + +L Q +Q +E I KIE L +
Sbjct: 586 EKRKQQLYTAMEERTEEIKVHKTMLAS-----QIRYVDQERENISTEFRERLSKIEKLKN 640
Query: 684 AVNSLNFII------KELTKRHNLL-----RNEVQGRDDALERRINEYALEMEDGLNKTM 732
L ++ +E T+ + ++ + E+Q D L+ +IN+ E+ L T+
Sbjct: 641 RYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIY-ALENTL 699
Query: 733 TIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLND-SIQTLVN 791
++N+ +NY K++ + +S+ ++ +E + + +R I+ L
Sbjct: 700 QVLNSC----NNNY--KQSFKKVTPSSD-EYELKIQLEEQKRAVDEKYRYKQRQIRELQE 752
Query: 792 DNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQ 839
D Q L V + LA + EKL++ +Q+ ET Q K ++
Sbjct: 753 DIQSMENTLDVIEHLANNVK-EKLSEKQAYS-FQLSKETEEQKPKLER 798
Score = 47.8 bits (112), Expect = 7e-05
Identities = 97/509 (19%), Positives = 216/509 (42%), Gaps = 67/509 (13%)
Query: 429 KVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT---CEKPIKELEVKQ 485
K+ E +S ++ L E R I + +H NV+QE+++T C+ +E E
Sbjct: 25 KLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETE--- 81
Query: 486 THLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLS-TEQVSDQKNA--PAAESVSN-- 540
+EH ++I E L + +++ + ++ S E+ SD++N A + +
Sbjct: 82 -------SEEHFKAIAQRE-LGRVKDEIQRLENEMASILEKKSDKENGIFKATQKLDGLK 133
Query: 541 -----NVTEYMSTLHENIKKQS-LMMLQMFEDLHIQESKINNLTVSLE-------MEKES 587
+ + L E+ K S + LQ + ++KI LT+ LE +++
Sbjct: 134 CQMNWDQQALEAWLEESAHKDSDALTLQKYAQQ--DDNKIRALTLQLERLTLECNQKRKI 191
Query: 588 LRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDME 647
L E + +S + +L ++ ++ E++ +N +++M ++ D+ +
Sbjct: 192 LDNELTETISA-----QLELDKAAQDFRKIHNERQELIKQWENTIEQMQKRDGDID-NCA 245
Query: 648 ILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTK------RHNL 701
+ ++Q ++ + E+ K + +I N T ++ ++L K H
Sbjct: 246 LELARIKQETREKENLVKEKIK---FLESEIGNNTEFEKRISVADRKLLKCRTAYQDHET 302
Query: 702 LRNEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEI 761
R +++G D+L+ +N + ++E L K ++ I D ++ L++T + N I
Sbjct: 303 SRIQLKGELDSLKATVNRTSSDLE-ALRKNISKIKK--DIHEETARLQKTKN---HNEII 356
Query: 762 HHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQ 821
K E ++ + L D ++ D + + L + K + E ++ +
Sbjct: 357 QTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQELQTETMKE 416
Query: 822 K-MYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQTLIPYYISV 880
K + T S ++ + L+ + L +I + + +Q +E ++++
Sbjct: 417 KAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQDFHIQQVERRMSRL-------- 468
Query: 881 KKGSVVTNERDQALQLQVLNSRFKALEAK 909
KG + +E QAL+ +++ R K+LE K
Sbjct: 469 -KGE-INSEEKQALEAKIVELR-KSLEEK 494
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 59.7 bits (143), Expect = 2e-08
Identities = 137/697 (19%), Positives = 264/697 (37%), Gaps = 103/697 (14%)
Query: 320 VMQKMTD---QVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSR-----EF 371
+MQ+ D QV +A L +++ D + T LE K+ E R E
Sbjct: 884 LMQEKNDLQLQVQAEADSLADAEERCDQLI-------KTKIQLEAKIKEVTERAEDEEEI 936
Query: 372 QSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVN 431
+ L K K + D E K +D++ T+A++ K + +++ + + ++
Sbjct: 937 NAELTAKKRK-----LEDECSELKKDI-DDLELTLAKVEKEKHATENKVKNLTEEMAGLD 990
Query: 432 ESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGA 491
E++ + ++K L + ++ TL D+ ++ T K +LE + LEG+
Sbjct: 991 ETIAKLTKEKK-ALQEAHQQTLDDL--------QAEEDKVNTLTKAKIKLEQQVDDLEGS 1041
Query: 492 LEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHE 551
LEQE + + K LK E + E Q + E + E MS L
Sbjct: 1042 LEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLD----EKLKKKEFE-MSGLQS 1096
Query: 552 NIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTE 611
I+ + + +Q+ + + +++I L +E E+ S R + E K R+D +L++
Sbjct: 1097 KIEDEQALGMQLQKKIKELQARIEELEEEIEAERAS-RAKAE----KQRSDLSRELEEIS 1151
Query: 612 ENLHVLNQTLA---EVLFPMDNKMDKMSEQLNDLTYDMEILQPLL---------EQGASL 659
E L + E+ + + KM L + T E L E G +
Sbjct: 1152 ERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQI 1211
Query: 660 RQTMTYEQ--PKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLR---NEVQGRDDALE 714
+Q KE ++ +I++L S + +++ L K L +E++ +++ +
Sbjct: 1212 DNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQ 1271
Query: 715 RRIN--------------EYALEMEDGLNKTMTIINNAIDFIQDNYALKETL-STIKDNS 759
R IN EY+ ++++ + F Q LK L IK S
Sbjct: 1272 RLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKS 1331
Query: 760 EIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKT---LAGIPRDEKLN 816
+ H S Q+ ++ L + N + +T I R E+L
Sbjct: 1332 ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELE 1391
Query: 817 QS---------NFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTT-----------KISK 856
++ + ++ + N + + K +Q + + E L++ K +
Sbjct: 1392 EAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQR 1451
Query: 857 NFETRLQDIESKVTQTLIPYYISVKKGSVVTNE--------RDQALQLQVLNSRFKALEA 908
NF+ L + + K +T S K+ ++ E + QL+ L K L+
Sbjct: 1452 NFDKILAEWKQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQ 1511
Query: 909 KSIHLSINFFSLNKTLHEVLTMCHNASTSVSELNATI 945
+ L+ K +HE+ + SEL A +
Sbjct: 1512 EISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAAL 1548
Score = 49.3 bits (116), Expect = 2e-05
Identities = 89/433 (20%), Positives = 178/433 (41%), Gaps = 54/433 (12%)
Query: 334 KLTLLQKKIDNISLTVNDVRNTYSS----LEGKVSEDKS--REFQSLLKGLKS--KSINV 385
+L QK+ ++S + ++N Y LE E+K+ +E L + + K I+
Sbjct: 1470 ELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHE 1529
Query: 386 L--IRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESV------VSI 437
L I+ V ++ Q ++E A L + Q+ +V+ + +
Sbjct: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589
Query: 438 AAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHL-----EGAL 492
+ +V+ + TL + RN + ++++M E + E+E++ H E
Sbjct: 1590 MKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKM----EGDLNEMEIQLNHANRMAAEALR 1645
Query: 493 EQEHSRSILYYESLN--KTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLH 550
++++IL L+ L +++ EQL E+ + N AE T +
Sbjct: 1646 NYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVER---RANLLQAEIEELRATLEQTERS 1702
Query: 551 ENIKKQSLM-MLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLK- 608
I +Q L+ + + LH Q + + N LE + ++GE ED++ + RN + K
Sbjct: 1703 RKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKA 1762
Query: 609 ---------------DTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLL 653
DT +L + + L + + + +++D+ +EQL L + +Q L
Sbjct: 1763 ITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDE-AEQL-ALKGGKKQIQKLE 1820
Query: 654 EQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDAL 713
+ L + EQ + + K + V L + +E R N+LR +Q D L
Sbjct: 1821 ARVRELEGEVESEQKRNVEAV-KGLRKHERKVKELTYQTEE--DRKNILR--LQDLVDKL 1875
Query: 714 ERRINEYALEMED 726
+ ++ Y + E+
Sbjct: 1876 QAKVKSYKRQAEE 1888
Score = 41.2 bits (95), Expect = 0.006
Identities = 69/343 (20%), Positives = 137/343 (39%), Gaps = 64/343 (18%)
Query: 530 KNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLR 589
K+A + ++N E+ T E + K ++ E + + N+L + ++ E +SL
Sbjct: 845 KSAETEKEMANMKEEFEKT-KEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLA 903
Query: 590 GECE--DMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDME 647
E D L K + + ++K+ E + AE + K K+ ++ ++L D++
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAE----LTAKKRKLEDECSELKKDID 959
Query: 648 ILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQ 707
L+ L + KE K++NLT + L+ I +LTK L+ Q
Sbjct: 960 DLELTLAK-----------VEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQ 1008
Query: 708 GRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTS 767
D L+ ED +N T+T + L++ + ++ + E K
Sbjct: 1009 QTLDDLQAE--------EDKVN-TLT---------KAKIKLEQQVDDLEGSLEQEKKIRM 1050
Query: 768 DMETILTFIPQFHRL-NDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQM 826
D+E + +L +S + ND Q+ DEKL + F+
Sbjct: 1051 DLERAKRKLEGDLKLAQESTMDIENDKQQL---------------DEKLKKKEFE----- 1090
Query: 827 FNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKV 869
+ S++ Q L++K+ K + R++++E ++
Sbjct: 1091 MSGLQSKIEDEQALGMQLQKKI-------KELQARIEELEEEI 1126
Score = 40.4 bits (93), Expect = 0.010
Identities = 131/792 (16%), Positives = 299/792 (37%), Gaps = 127/792 (16%)
Query: 334 KLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLK----SKSINVLIRD 389
K+ LQ +I+ + + R + + E K D SRE + + + L+ + S + +
Sbjct: 1111 KIKELQARIEELEEEIEAERASRAKAE-KQRSDLSRELEEISERLEEAGGATSAQIEMNK 1169
Query: 390 IVREQFKIFQNDMQE-------TVAQLFK----TVSSLSEDLESTRQIIQKVNESVVSIA 438
+F+ + D++E T A L K +V+ L E +++ +++ QK+ + +
Sbjct: 1170 KREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMK 1229
Query: 439 AQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQ---- 494
+ + + + + + + ++ ++M E + E++ K+ + +
Sbjct: 1230 ME-----IDDLASNMETVSKAKGNL----EKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
Query: 495 ---------EHSRSILYYESLNKTLSKLKEV----------------------------- 516
E+SR + ++L LS+ K+
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLEEEIKAKSALAHALQSS 1340
Query: 517 -HEQLLSTEQVSDQKNAPA----AESVSNNVTEYMSTLHEN--------IKKQSLMMLQM 563
H+ L EQ +++ A A A S +N+ T +E +++ + Q
Sbjct: 1341 RHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQR 1400
Query: 564 FEDLHIQESKINNLTVSLEMEKESLRGECEDMLSKCR--NDFKFQLKDTEENLHVLNQTL 621
+D +N SLE K+ L+ E ED++ N L + N +
Sbjct: 1401 LQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEW 1460
Query: 622 AEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENL 681
+ +++ ++ L+ ++ ++ E+ +T+ E ++++I +L
Sbjct: 1461 KQKCEETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKN----LQQEISDL 1516
Query: 682 TSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEYALEMEDG-LNKTMTIINNAID 740
T + I EL K + E ALE E +LE E+G + + +N
Sbjct: 1517 TEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEA--EASLEHEEGKILRIQLELNQVKS 1574
Query: 741 FIQDNYALK-ETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSI---QTLVNDNQRY 796
+ A K E + +K N H + M++ T + ND+I + + D
Sbjct: 1575 EVDRKIAEKDEEIDQMKRN---HIRIVESMQS--TLDAEIRSRNDAIRLKKKMEGDLNEM 1629
Query: 797 NFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISK 856
L A +A E L N++ + +T + ++ L+E+L + + +
Sbjct: 1630 EIQLNHANRMAA----EALR--NYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRAN 1683
Query: 857 NFETRLQDIESKVTQTLIPYYISVKKGSVVTNE-RDQALQLQVLNSRFKALEAKSIHLSI 915
+ ++++ + + QT + + E D + ++Q+L+++ +L L
Sbjct: 1684 LLQAEIEELRATLEQT-------ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Query: 916 NFFSLNKTLHEVLTMCHNASTSVSE------LNATIPKWIKHSLPDIQLLQKGLTEFVEP 969
+ + + +++ NA + + A K + + ++ ++K L + V+
Sbjct: 1737 DISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKD 1796
Query: 970 IIQIKTQAALSNLTCCIDRSLPGSLANVVKSQKQVKSLPKKINALKKPTVNLTTVLIGRT 1029
+ +A +L G + K + +V+ L ++ + +K V L +
Sbjct: 1797 LQHRLDEAE--------QLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGL-RKH 1847
Query: 1030 QRNTDNIIYPEE 1041
+R + Y E
Sbjct: 1848 ERKVKELTYQTE 1859
Score = 40.0 bits (92), Expect = 0.014
Identities = 52/276 (18%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 322 QKMTDQVNYQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSK 381
+ + +Q+ + LLQ +I+ + T+ + E ++ + R LL +
Sbjct: 1669 EDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERV--QLLHTQNTS 1726
Query: 382 SINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQ 441
IN + + Q +M++ + + + + + +++ + Q
Sbjct: 1727 LINT--KKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE------QD 1778
Query: 442 KFVLVQENRPTLTDIVELRNHIVNVRQEMTLTC-EKPIKELEVKQTHLEGALEQEHSRSI 500
++ + L V+ H ++ +++ L +K I++LE + LEG +E E R++
Sbjct: 1779 TSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNV 1838
Query: 501 LYYESLNKTLSKLKEVHEQL----------------LSTEQVSDQKNAPAAESVSN-NVT 543
+ L K K+KE+ Q L + S ++ A AE SN N++
Sbjct: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
Query: 544 EYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTV 579
++ HE + + E I ES++N L V
Sbjct: 1899 KFRRIQHE--------LEEAEERADIAESQVNKLRV 1926
Score = 30.8 bits (68), Expect = 8.3
Identities = 52/247 (21%), Positives = 96/247 (38%), Gaps = 24/247 (9%)
Query: 279 KCQLRAQEQQSLIHTNQA-ESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTL 337
+ QL + SLI+T + E+ + +G E Q+ E +K A +L
Sbjct: 1716 RVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKK 1775
Query: 338 LQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKI 397
Q ++ ++ T L+ ++ E + Q LKG K + + R VRE
Sbjct: 1776 EQDTSAHLERMKKNLEQTVKDLQHRLDEAE----QLALKGGKKQIQKLEAR--VRELEGE 1829
Query: 398 FQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIV 457
+++ + V E ++ R+ +KV E +K +L L D+V
Sbjct: 1830 VESEQKRNV-----------EAVKGLRKHERKVKELTYQTEEDRKNIL------RLQDLV 1872
Query: 458 ELRNHIVNVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVH 517
+ V + E+ K ++ LE+ R+ + +NK K +EVH
Sbjct: 1873 DKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVH 1932
Query: 518 EQLLSTE 524
+++S E
Sbjct: 1933 TKIISEE 1939
>gi|50428933 C1q domain containing 1 isoform 1 [Homo sapiens]
Length = 1127
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/131 (30%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 1101 VAFFASHTYGM---TIPGPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTIESFSAH 1157
VAF A+ T + T+ PI+F+ L N G ++ + G+F P G YVF + + + +
Sbjct: 998 VAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFIFHMLKLAVN 1057
Query: 1158 ISGFL-VVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQEVWLRLAKGTIPAKFPP 1216
+ ++ ++ + L N + H + A+L+L G ++WLRL +G I
Sbjct: 1058 VPLYVNLMKNEEVLVSAYANDGAPDH--ETASNHAILQLFQGDQIWLRLHRGAIYGSSWK 1115
Query: 1217 VTTFSGYLLYR 1227
+TFSGYLLY+
Sbjct: 1116 YSTFSGYLLYQ 1126
>gi|50428931 C1q domain containing 1 isoform 3 [Homo sapiens]
Length = 793
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/131 (30%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 1101 VAFFASHTYGM---TIPGPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTIESFSAH 1157
VAF A+ T + T+ PI+F+ L N G ++ + G+F P G YVF + + + +
Sbjct: 664 VAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFIFHMLKLAVN 723
Query: 1158 ISGFL-VVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQEVWLRLAKGTIPAKFPP 1216
+ ++ ++ + L N + H + A+L+L G ++WLRL +G I
Sbjct: 724 VPLYVNLMKNEEVLVSAYANDGAPDH--ETASNHAILQLFQGDQIWLRLHRGAIYGSSWK 781
Query: 1217 VTTFSGYLLYR 1227
+TFSGYLLY+
Sbjct: 782 YSTFSGYLLYQ 792
>gi|23503235 C1q domain containing 1 isoform 2 [Homo sapiens]
Length = 1077
Score = 59.7 bits (143), Expect = 2e-08
Identities = 40/131 (30%), Positives = 68/131 (51%), Gaps = 6/131 (4%)
Query: 1101 VAFFASHTYGM---TIPGPILFNNLDVNYGASYTPRTGKFRIPYLGVYVFKYTIESFSAH 1157
VAF A+ T + T+ PI+F+ L N G ++ + G+F P G YVF + + + +
Sbjct: 948 VAFSAARTSNLAPGTLDQPIVFDLLLNNLGETFDLQLGRFNCPVNGTYVFIFHMLKLAVN 1007
Query: 1158 ISGFL-VVDGIDKLAFESENINSEIHCDRVLTGDALLELNYGQEVWLRLAKGTIPAKFPP 1216
+ ++ ++ + L N + H + A+L+L G ++WLRL +G I
Sbjct: 1008 VPLYVNLMKNEEVLVSAYANDGAPDH--ETASNHAILQLFQGDQIWLRLHRGAIYGSSWK 1065
Query: 1217 VTTFSGYLLYR 1227
+TFSGYLLY+
Sbjct: 1066 YSTFSGYLLYQ 1076
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 59.3 bits (142), Expect = 2e-08
Identities = 126/659 (19%), Positives = 276/659 (41%), Gaps = 121/659 (18%)
Query: 309 QQQQQGCGDPEVMQKMTDQVN-YQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDK 367
Q ++Q E ++ T V YQAM +T L++ ++ +VR ++E ++ E
Sbjct: 943 QTEEQVNDLKERLKTSTSNVEQYQAM-VTSLEESLNKEKQVTEEVRK---NIEVRLKE-- 996
Query: 368 SREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDLESTRQII 427
S EFQ+ L+ K + +++ ++ + ++ M++ +++L KT+SS+ +++ Q
Sbjct: 997 SAEFQTQLEK-KLMEVEKEKQELQDDKRRAIES-MEQQLSELKKTLSSVQNEVQEALQRA 1054
Query: 428 QKV------------NESVVSIAAQQKFV-----------LVQENRPTLTDIVELRNHIV 464
++ +++ AQ K+ +Q + ++ + +R H+
Sbjct: 1055 STALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQAAKEQVSKMASVRQHL- 1113
Query: 465 NVRQEMTLTCEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTE 524
+E T E + E + E L+ E S+ + E L K + + +H+Q+ E
Sbjct: 1114 ---EETTQKAESQLLECKASWEERERMLKDEVSKCVCRCEDLEK---QNRLLHDQI---E 1164
Query: 525 QVSDQKNAPAAESVSN--NVT----------------------EYMSTLHENIKKQSLMM 560
++SD+ A E V NV+ E T E + +SL
Sbjct: 1165 KLSDKVVASVKEGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESLRY 1224
Query: 561 LQMFEDLHIQESKINNLTVSLEMEKESLR------GECEDMLSKCRN-----DFKFQLKD 609
Q E L E ++ L SL E+E ++ + E+++ K + L++
Sbjct: 1225 RQRVELL---ERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 610 TEENLHV-LNQTLAEV------LFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQT 662
+E L L Q A+V + P+ ++SE+ L + ++L+ +++ + Q
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 663 MTYEQP-----------KEAIVIRKKIENLTSAVNSLNFIIKE----LTKRHNLLR---- 703
+ +Q E V K+I+ LT + L I LT NL++
Sbjct: 1342 LVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKE 1401
Query: 704 --NEVQGRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYA--------LKETLS 753
N+V+ + +++ ++ +++++ + KT+T + + Y + ET +
Sbjct: 1402 DLNKVRTEKETIQKDLDAKIIDIQEKV-KTITQVKKIGRRYKTQYEELKAQQDKVMETSA 1460
Query: 754 TIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDE 813
+ + H +M+ + + Q + S+++ V + Q+ L +T A +++
Sbjct: 1461 QSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQK---TLSEKETEARNLQEQ 1517
Query: 814 KLN-QSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKVTQ 871
+ QS ++ Q + T+Q + +Q ++ EEK +K+ L ++ ++T+
Sbjct: 1518 TVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSKIAHLAGVKDQLTK 1576
Score = 57.8 bits (138), Expect = 6e-08
Identities = 86/417 (20%), Positives = 180/417 (43%), Gaps = 53/417 (12%)
Query: 334 KLTLLQKKIDNISLTVNDVRNTYSSLEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVRE 393
++ LL++++ + ++N R +V+ + + L+K ++ ++ + ++RE
Sbjct: 1227 RVELLERELQELQDSLNAEREKV-----QVTAKTMAQHEELMKKTETMNVVMETNKMLRE 1281
Query: 394 QFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQK----------VNESVVSIAAQQKF 443
+ + + D+Q+ A++ K + E+ ++ +K + E V A+ +
Sbjct: 1282 EKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQH 1341
Query: 444 VLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKPIKELEVKQTHLE-GALEQEHSRSILY 502
++ Q+ P D E R L EK + ++Q E G L+ E +RS
Sbjct: 1342 LVSQQKDP---DTEEYRK----------LLSEKEVHTKRIQQLTEEIGRLKAEIARSNAS 1388
Query: 503 YESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQ 562
+ + LKE ++ TE+ + QK+ A ++ E + T+ + +KK
Sbjct: 1389 LTNNQNLIQSLKEDLNKV-RTEKETIQKDLDAKII---DIQEKVKTITQ-VKKIGRRYKT 1443
Query: 563 MFEDLHIQESKINNLTVSLEMEKESLRGECEDM--LSKCRNDFKFQLKDTEENLHVLNQT 620
+E+L Q+ K+ + + + ++M L + N + + K E + L +T
Sbjct: 1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT 1503
Query: 621 LAEVLFPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPK--EAIVIRK-K 677
L+E N ++ + ++L+ + LQ Q LRQ +T ++ K +AIV K K
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVAAKSK 1563
Query: 678 IENLTSAVNSLNFIIKELTKRHNLL--------------RNEVQGRDDALERRINEY 720
I +L + L +EL +R+ L +++ +GR LER + E+
Sbjct: 1564 IAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLERELREH 1620
Score = 52.0 bits (123), Expect = 3e-06
Identities = 132/669 (19%), Positives = 260/669 (38%), Gaps = 118/669 (17%)
Query: 372 QSLLKGLKSKSINVLIRDIVRE---QFKIFQNDMQETVAQLFKTVSSLSEDLESTRQIIQ 428
Q LL+ L++K IN + +IV+E + I + +E + K V+SLS LE + IQ
Sbjct: 408 QLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREE-YERAQKAVASLSVKLEQAMKEIQ 466
Query: 429 KVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMT-LTCEKPIKELEVKQTH 487
++ E A +Q VL ++NR + +L I + E+ I++ EV
Sbjct: 467 RLQEDTDK-ANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSAD 525
Query: 488 LEGALEQEHSRSILYYESLNKTLSKLKEVHEQLL-STEQVSDQKNAPAAESVSNNVTEYM 546
+ + E + Y + + +L++ +++LL + ++ + + E+ S+ +TE
Sbjct: 526 ISSSSEVISQHLVSY-----RNIEELQQQNQRLLVALRELGETREREEQETTSSKITELQ 580
Query: 547 STLH------ENIKKQSLMMLQMFEDLHIQESKINNLT-----VSLEMEKESLRG----- 590
L E ++K +Q+ + + Q L V++ + SL
Sbjct: 581 LKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLAS 640
Query: 591 --------------------------ECEDMLSKCRNDFKFQLKDTEENLHVLNQTLA-- 622
E + L + + F+ K+ EN + N+ L
Sbjct: 641 TPKRPSTSQTVSTPAPVPVIESTEAIEAKAALKQLQEIFENYKKEKAENEKIQNEQLEKL 700
Query: 623 -EVLFPMDNKMDKMSEQLNDLTYDMEILQPLLE----QGASLRQ-----TMTYEQPKEAI 672
E + + ++ K+S QL+ + E+LQ +E + SL + T T ++ ++ I
Sbjct: 701 QEQVTDLRSQNTKISTQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATTQKQEQII 760
Query: 673 ---------------VIRKKIENLTSAVNSLNFIIKELTKRH----------NLLRNEVQ 707
V + ENL L L+++ NLL +Q
Sbjct: 761 NTMTQDLRGANEKLAVAEVRAENLKKEKEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQ 820
Query: 708 GRDDALERRINEYALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSEIHHKCTS 767
LER E + + K I++ +++ + TL+ D + K
Sbjct: 821 TIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQL 880
Query: 768 DMETILTFIPQFHRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMF 827
D ET L + N + N +QVA + R K SN + +
Sbjct: 881 DTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQSS--QRTGKGQPSNKEDV---- 934
Query: 828 NETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDI------ESKVTQTL-------- 873
++ SQ+R+ ++ ++ L+E+L +T + ++ + + E +VT+ +
Sbjct: 935 DDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEVRKNIEVRL 994
Query: 874 ---IPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTM 930
+ ++K + + Q LQ + + +A+E+ LS +L+ +EV
Sbjct: 995 KESAEFQTQLEKKLMEVEKEKQELQ----DDKRRAIESMEQQLSELKKTLSSVQNEVQEA 1050
Query: 931 CHNASTSVS 939
AST++S
Sbjct: 1051 LQRASTALS 1059
Score = 50.4 bits (119), Expect = 1e-05
Identities = 114/568 (20%), Positives = 239/568 (42%), Gaps = 71/568 (12%)
Query: 366 DKSREFQSL----------LKGLKSKSINVLI---RDI-VREQFKIFQNDMQETVAQLFK 411
+++RE QSL LK L K+ + I R+I ++ QF + +++ L +
Sbjct: 70 NETRECQSLRLELEKLNNQLKALTEKNKELEIAQDRNIAIQSQFTRTKEELEAEKRDLIR 129
Query: 412 TVSSLSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDI-VELRNHIVNVRQEM 470
T LS++LE + ++++NE + + + ++ + +D+ V+ R + +E+
Sbjct: 130 TNERLSQELEYLTEDVKRLNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKEL 189
Query: 471 TLTCEKPIK-ELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQ 529
+ + EL+ K L AL +E IL L L KE +L EQ++
Sbjct: 190 LHSQNTWLNTELKTKTDELL-ALGREKGNEIL---ELKCNLENKKEEVSRL--EEQMNGL 243
Query: 530 KNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLR 589
K + E + +V + ++ L E K+Q M + F + K++NL S + E+
Sbjct: 244 KT--SNEHLQKHVEDLLTKLKE-AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKS 300
Query: 590 GECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEIL 649
E L++ + LK+ E + L EV D +M E++ L ++E
Sbjct: 301 NE----LTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQMEKEMLEKIGRLEKELENA 356
Query: 650 QPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGR 709
LL + + K AI+ +++ ++ ++ I+K K L V+ +
Sbjct: 357 NDLL----------SATKRKGAILSEEELAAMSPTAAAVAKIVKPGMKLTELYNAYVETQ 406
Query: 710 DDAL-----ERRINEYALEMEDGLNKTMTIINN------------AIDFIQDNYALKETL 752
D L +RIN+Y E+ + I+ A ++ A+KE +
Sbjct: 407 DQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQKAVASLSVKLEQAMKE-I 465
Query: 753 STIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVND-NQRYNFVLQVAKTLAG--I 809
++++++ +K +S +E R N ++ V D +Q+ +L + G +
Sbjct: 466 QRLQEDTDKANKQSSVLE----------RDNRRMEIQVKDLSQQIRVLLMELEEARGNHV 515
Query: 810 PRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQD-IESK 868
RDE+++ ++ ++ ++ R ++ + L+ ++ + E Q+ SK
Sbjct: 516 IRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQETTSSK 575
Query: 869 VTQTLIPYYISVKKGSVVTNERDQALQL 896
+T+ + ++ + + R +QL
Sbjct: 576 ITELQLKLESALTELEQLRKSRQHQMQL 603
Score = 43.9 bits (102), Expect = 0.001
Identities = 152/860 (17%), Positives = 320/860 (37%), Gaps = 182/860 (21%)
Query: 283 RAQEQQSLIHTNQAESHT----------AVGRGVAEQQQQQGCG---DPEVMQKMTDQVN 329
R ++++ L+H+ +T A+GR + + C E + ++ +Q+N
Sbjct: 182 RLEQEKELLHSQNTWLNTELKTKTDELLALGREKGNEILELKCNLENKKEEVSRLEEQMN 241
Query: 330 YQAMKLTLLQKKIDNISLTVNDVRNTYSSLEGKV--------------------SEDKS- 368
LQK ++++ + + + +S+E K SE KS
Sbjct: 242 GLKTSNEHLQKHVEDLLTKLKEAKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSN 301
Query: 369 ------REFQSLLK--GLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSSLSEDL 420
E LLK G +K+I + ++ + + ++ + +M E + +L K + + ++ L
Sbjct: 302 ELTRAVEELHKLLKEAGEANKAIQDHLLEVEQSKDQM-EKEMLEKIGRLEKELENANDLL 360
Query: 421 ESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT------- 473
+T++ ++E ++ + + + +P + + EL N V + ++ L
Sbjct: 361 SATKRKGAILSEEELAAMSPTAAAVAKIVKPGM-KLTELYNAYVETQDQLLLEKLENKRI 419
Query: 474 ---CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQ--VSD 528
++ +KE+E K L+ E+ YE K ++ L EQ + Q D
Sbjct: 420 NKYLDEIVKEVEAKAPILKRQREE--------YERAQKAVASLSVKLEQAMKEIQRLQED 471
Query: 529 QKNAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLH----IQESKINNLTVSLEME 584
A SV M +++ +Q ++L E+ I++ ++++ +S E
Sbjct: 472 TDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSE 531
Query: 585 K-----------ESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVLFPMDNKMD 633
E L+ + + +L R + + ++ +E + + E+ +++ +
Sbjct: 532 VISQHLVSYRNIEELQQQNQRLLVALRELGETREREEQE---TTSSKITELQLKLESALT 588
Query: 634 KMSEQLNDLTYDMEILQPLLEQ---------------------------------GASLR 660
++ + + M+++ ++ Q S
Sbjct: 589 ELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAIPLHASSLDDVSLASTPKRPSTS 648
Query: 661 QTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEVQGRDDALERRINEY 720
QT++ P I + IE +A+ L I + K + ++ ++ E
Sbjct: 649 QTVSTPAPVPVIESTEAIE-AKAALKQLQEIFENYKKE--------KAENEKIQNEQLEK 699
Query: 721 ALEMEDGLNKTMTIINNAIDFIQDNYALKETLSTIKDNSE-IHHKCTSDMETILTFIPQF 779
E L T I+ +DF Y + ++DN E + TS E
Sbjct: 700 LQEQVTDLRSQNTKISTQLDFASKRYEM------LQDNVEGYRREITSLHERNQKLTATT 753
Query: 780 HRLNDSIQTLVNDNQRYNFVLQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQ 839
+ I T+ D + N L VA+ A N +K +M S+VR QQ
Sbjct: 754 QKQEQIINTMTQDLRGANEKLAVAEVRA----------ENLKKEKEMLK--LSEVRLSQQ 801
Query: 840 NMSHLEEK----LLLT-------------TKISKNFETRLQDIESKVTQTLIPYYISVKK 882
S L E+ LLLT T+ + ++++ +E +++ V++
Sbjct: 802 RESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQ 861
Query: 883 GSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLTMCHNASTS----V 938
+T L +Q+L+++ + ++HL+ L E+ T+ + S
Sbjct: 862 RHTLTRN----LDVQLLDTKRQLDTETNLHLNTKEL-LKNAQKEIATLKQHLSNMEVQVA 916
Query: 939 SELNATIPKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQAALSNLTCCIDRSLPGSLANVV 998
S+ + K + D+ L L + E + +K + L S +NV
Sbjct: 917 SQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKER-------------LKTSTSNVE 963
Query: 999 KSQKQVKSLPKKINALKKPT 1018
+ Q V SL + +N K+ T
Sbjct: 964 QYQAMVTSLEESLNKEKQVT 983
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 58.9 bits (141), Expect = 3e-08
Identities = 117/590 (19%), Positives = 226/590 (38%), Gaps = 72/590 (12%)
Query: 418 EDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKP 477
++L+ T++ QK + + +QK + E + L + ++ + +EM +
Sbjct: 859 DELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 916
Query: 478 IKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAES 537
+ELE +E LE+E R + ++ K++ +Q+L E+ +++ A +
Sbjct: 917 KQELEEILHEMEARLEEEEDRG-------QQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 538 VSNNVT--EYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDM 595
VT + L + I ++ ++ + E +I++LT +L E+E +
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN----- 1024
Query: 596 LSKCRNDFKFQLKDTEENL---HVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPL 652
L+K +N + + + E L Q L ++ ++ EQ+ DL + L+
Sbjct: 1025 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1084
Query: 653 LE------QGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEV 706
L Q A R Q A+ KKI L ++ L +E RN+
Sbjct: 1085 LAKKEEELQAALARLDDEIAQKNNAL---KKIRELEGHISDL----QEDLDSERAARNKA 1137
Query: 707 QGRDDALERRINEYALEMEDGLNKT-------------MTIINNAIDFIQDNYALKETLS 753
+ + L + E+ED L+ T +T++ A+D +ET S
Sbjct: 1138 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD--------EETRS 1189
Query: 754 TIKDNSEIHHKCTSDMETILTFIPQFHR----LNDSIQTLVNDNQRYNFVLQVAKTLAGI 809
E+ K +E + + QF R L+ + QTL +N +A L +
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN------ADLAGELRVL 1243
Query: 810 PRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKV 869
+ ++ + +K+ E S+ ++ + L +K+ ++ L + E K
Sbjct: 1244 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1303
Query: 870 TQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLT 929
+ L S+ T E Q Q LN + K L SL L E +
Sbjct: 1304 IK-LAKDVASLSSQLQDTQELLQEETRQKLN-----VSTKLRQLEEERNSLQDQLDEEME 1357
Query: 930 MCHNASTSVSELNATI---PKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQ 976
N +S LN + K ++ ++ L++G F + I + Q
Sbjct: 1358 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Score = 51.6 bits (122), Expect = 5e-06
Identities = 115/667 (17%), Positives = 260/667 (38%), Gaps = 123/667 (18%)
Query: 281 QLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQK 340
+LRA+ +Q + T + + + E+ + E+ QK V +L ++
Sbjct: 1167 ELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1217
Query: 341 KIDNISLTVNDVRNTYSSLEGKVS---------EDKSREFQSLLKGLKSK---------S 382
N+ + + L G++ E K ++ ++ ++ L+SK
Sbjct: 1218 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1277
Query: 383 INVLIRDIVREQFKI--FQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQ 440
+N + + E + N+ + +L K V+SLS L+ T++++Q+ ++++
Sbjct: 1278 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST- 1336
Query: 441 QKFVLVQENRPTLTDIVE--------LRNHIVNVRQEMTLTCEK------PIKELEVKQT 486
K ++E R +L D ++ L HI + +++ + +K ++ LE +
Sbjct: 1337 -KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1395
Query: 487 HLEGALE---QEHSRSILYYESLNKTLSKLKEV------------------------HEQ 519
+ +E Q++ Y+ L KT ++L++ +Q
Sbjct: 1396 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1455
Query: 520 LLSTEQ-----VSDQKNAPAAE---------SVSNNVTEYMSTLHENIKKQSLMMLQMFE 565
LL+ E+ +D+++ AE S++ + E + E +++ + M+ E
Sbjct: 1456 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA-KEELERTNKMLKAEME 1514
Query: 566 DLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVL 625
DL + + LE K +L + E+M K QL++ E+ L Q +
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRALETQMEEM--------KTQLEELEDEL----QATEDAK 1562
Query: 626 FPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAV 685
++ M + Q D++ E+ Q +E E RK+ +A
Sbjct: 1563 LRLEVNMQALKGQFE---RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 1619
Query: 686 NSLNFIIKELTKRHNLLRNEVQGRDDA------LERRINEYALEMEDGLNKTMTIINNAI 739
L +K+L + + + ++GR++A L+ ++ ++ E+ED I A
Sbjct: 1620 KKLEGDLKDLELQAD---SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1676
Query: 740 DFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFV 799
+ + +L+ L ++++ + + + + + S + + D +R
Sbjct: 1677 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR---- 1732
Query: 800 LQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFE 859
++ +A + + + Q N + M + +VRK Q L +L ++ E
Sbjct: 1733 -RLEARIAQLEEELEEEQGNMEAM-------SDRVRKATQQAEQLSNELATERSTAQKNE 1784
Query: 860 TRLQDIE 866
+ Q +E
Sbjct: 1785 SARQQLE 1791
Score = 42.0 bits (97), Expect = 0.004
Identities = 55/248 (22%), Positives = 107/248 (43%), Gaps = 30/248 (12%)
Query: 359 LEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVA---QLFKTVSS 415
LEG + +D + S +KG + ++I L + ++ Q K FQ ++++ A ++F T
Sbjct: 1622 LEGDL-KDLELQADSAIKG-REEAIKQLRK--LQAQMKDFQRELEDARASRDEIFATAKE 1677
Query: 416 LSEDLESTRQIIQKVNESVVSI--AAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT 473
+ +S + ++ E + + A +Q + +E L + RN + + +
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK------ 1731
Query: 474 CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQL---LSTEQVSDQK 530
+ LE + LE LE+E E+++ + K + EQL L+TE+ + QK
Sbjct: 1732 -----RRLEARIAQLEEELEEEQGNM----EAMSDRVRKATQQAEQLSNELATERSTAQK 1782
Query: 531 NAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRG 590
N A + + E S LHE + + + + E+KI L +E E +
Sbjct: 1783 NESARQQLERQNKELRSKLHE---MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQA 1839
Query: 591 ECEDMLSK 598
+ + K
Sbjct: 1840 ATKSLKQK 1847
Score = 35.0 bits (79), Expect = 0.44
Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 26/174 (14%)
Query: 357 SSLEGKVS-EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSS 415
SSL G+ + +D+ R ++ + L+ ++ EQ + M + V + +
Sbjct: 1719 SSLSGRNALQDEKRRLEARIAQLEE--------ELEEEQGNM--EAMSDRVRKATQQAEQ 1768
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCE 475
LS +L + R QK NES A QQ L ++N+ ELR+ + + + +
Sbjct: 1769 LSNELATERSTAQK-NES----ARQQ---LERQNK-------ELRSKLHEMEGAVKSKFK 1813
Query: 476 KPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQ 529
I LE K LE +EQE +SL + KLKE+ Q+ ++++Q
Sbjct: 1814 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1867
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 58.9 bits (141), Expect = 3e-08
Identities = 117/590 (19%), Positives = 226/590 (38%), Gaps = 72/590 (12%)
Query: 418 EDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKP 477
++L+ T++ QK + + +QK + E + L + ++ + +EM +
Sbjct: 866 DELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923
Query: 478 IKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAES 537
+ELE +E LE+E R + ++ K++ +Q+L E+ +++ A +
Sbjct: 924 KQELEEILHEMEARLEEEEDRG-------QQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 538 VSNNVT--EYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDM 595
VT + L + I ++ ++ + E +I++LT +L E+E +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN----- 1031
Query: 596 LSKCRNDFKFQLKDTEENL---HVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPL 652
L+K +N + + + E L Q L ++ ++ EQ+ DL + L+
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 653 LE------QGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEV 706
L Q A R Q A+ KKI L ++ L +E RN+
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNAL---KKIRELEGHISDL----QEDLDSERAARNKA 1144
Query: 707 QGRDDALERRINEYALEMEDGLNKT-------------MTIINNAIDFIQDNYALKETLS 753
+ + L + E+ED L+ T +T++ A+D +ET S
Sbjct: 1145 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD--------EETRS 1196
Query: 754 TIKDNSEIHHKCTSDMETILTFIPQFHR----LNDSIQTLVNDNQRYNFVLQVAKTLAGI 809
E+ K +E + + QF R L+ + QTL +N +A L +
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN------ADLAGELRVL 1250
Query: 810 PRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKV 869
+ ++ + +K+ E S+ ++ + L +K+ ++ L + E K
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1310
Query: 870 TQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLT 929
+ L S+ T E Q Q LN + K L SL L E +
Sbjct: 1311 IK-LAKDVASLSSQLQDTQELLQEETRQKLN-----VSTKLRQLEEERNSLQDQLDEEME 1364
Query: 930 MCHNASTSVSELNATI---PKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQ 976
N +S LN + K ++ ++ L++G F + I + Q
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Score = 51.6 bits (122), Expect = 5e-06
Identities = 115/667 (17%), Positives = 260/667 (38%), Gaps = 123/667 (18%)
Query: 281 QLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQK 340
+LRA+ +Q + T + + + E+ + E+ QK V +L ++
Sbjct: 1174 ELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 341 KIDNISLTVNDVRNTYSSLEGKVS---------EDKSREFQSLLKGLKSK---------S 382
N+ + + L G++ E K ++ ++ ++ L+SK
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 383 INVLIRDIVREQFKI--FQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQ 440
+N + + E + N+ + +L K V+SLS L+ T++++Q+ ++++
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST- 1343
Query: 441 QKFVLVQENRPTLTDIVE--------LRNHIVNVRQEMTLTCEK------PIKELEVKQT 486
K ++E R +L D ++ L HI + +++ + +K ++ LE +
Sbjct: 1344 -KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Query: 487 HLEGALE---QEHSRSILYYESLNKTLSKLKEV------------------------HEQ 519
+ +E Q++ Y+ L KT ++L++ +Q
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 520 LLSTEQ-----VSDQKNAPAAE---------SVSNNVTEYMSTLHENIKKQSLMMLQMFE 565
LL+ E+ +D+++ AE S++ + E + E +++ + M+ E
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA-KEELERTNKMLKAEME 1521
Query: 566 DLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVL 625
DL + + LE K +L + E+M K QL++ E+ L Q +
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEM--------KTQLEELEDEL----QATEDAK 1569
Query: 626 FPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAV 685
++ M + Q D++ E+ Q +E E RK+ +A
Sbjct: 1570 LRLEVNMQALKGQFE---RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 1626
Query: 686 NSLNFIIKELTKRHNLLRNEVQGRDDA------LERRINEYALEMEDGLNKTMTIINNAI 739
L +K+L + + + ++GR++A L+ ++ ++ E+ED I A
Sbjct: 1627 KKLEGDLKDLELQAD---SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1683
Query: 740 DFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFV 799
+ + +L+ L ++++ + + + + + S + + D +R
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR---- 1739
Query: 800 LQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFE 859
++ +A + + + Q N + M + +VRK Q L +L ++ E
Sbjct: 1740 -RLEARIAQLEEELEEEQGNMEAM-------SDRVRKATQQAEQLSNELATERSTAQKNE 1791
Query: 860 TRLQDIE 866
+ Q +E
Sbjct: 1792 SARQQLE 1798
Score = 42.0 bits (97), Expect = 0.004
Identities = 55/248 (22%), Positives = 107/248 (43%), Gaps = 30/248 (12%)
Query: 359 LEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVA---QLFKTVSS 415
LEG + +D + S +KG + ++I L + ++ Q K FQ ++++ A ++F T
Sbjct: 1629 LEGDL-KDLELQADSAIKG-REEAIKQLRK--LQAQMKDFQRELEDARASRDEIFATAKE 1684
Query: 416 LSEDLESTRQIIQKVNESVVSI--AAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT 473
+ +S + ++ E + + A +Q + +E L + RN + + +
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK------ 1738
Query: 474 CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQL---LSTEQVSDQK 530
+ LE + LE LE+E E+++ + K + EQL L+TE+ + QK
Sbjct: 1739 -----RRLEARIAQLEEELEEEQGNM----EAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 531 NAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRG 590
N A + + E S LHE + + + + E+KI L +E E +
Sbjct: 1790 NESARQQLERQNKELRSKLHE---MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQA 1846
Query: 591 ECEDMLSK 598
+ + K
Sbjct: 1847 ATKSLKQK 1854
Score = 35.0 bits (79), Expect = 0.44
Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 26/174 (14%)
Query: 357 SSLEGKVS-EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSS 415
SSL G+ + +D+ R ++ + L+ ++ EQ + M + V + +
Sbjct: 1726 SSLSGRNALQDEKRRLEARIAQLEE--------ELEEEQGNM--EAMSDRVRKATQQAEQ 1775
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCE 475
LS +L + R QK NES A QQ L ++N+ ELR+ + + + +
Sbjct: 1776 LSNELATERSTAQK-NES----ARQQ---LERQNK-------ELRSKLHEMEGAVKSKFK 1820
Query: 476 KPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQ 529
I LE K LE +EQE +SL + KLKE+ Q+ ++++Q
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 58.9 bits (141), Expect = 3e-08
Identities = 117/590 (19%), Positives = 226/590 (38%), Gaps = 72/590 (12%)
Query: 418 EDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCEKP 477
++L+ T++ QK + + +QK + E + L + ++ + +EM +
Sbjct: 866 DELQKTKERQQKAENELKEL--EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAK 923
Query: 478 IKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQKNAPAAES 537
+ELE +E LE+E R + ++ K++ +Q+L E+ +++ A +
Sbjct: 924 KQELEEILHEMEARLEEEEDRG-------QQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 538 VSNNVT--EYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRGECEDM 595
VT + L + I ++ ++ + E +I++LT +L E+E +
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKN----- 1031
Query: 596 LSKCRNDFKFQLKDTEENL---HVLNQTLAEVLFPMDNKMDKMSEQLNDLTYDMEILQPL 652
L+K +N + + + E L Q L ++ ++ EQ+ DL + L+
Sbjct: 1032 LTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQ 1091
Query: 653 LE------QGASLRQTMTYEQPKEAIVIRKKIENLTSAVNSLNFIIKELTKRHNLLRNEV 706
L Q A R Q A+ KKI L ++ L +E RN+
Sbjct: 1092 LAKKEEELQAALARLDDEIAQKNNAL---KKIRELEGHISDL----QEDLDSERAARNKA 1144
Query: 707 QGRDDALERRINEYALEMEDGLNKT-------------MTIINNAIDFIQDNYALKETLS 753
+ + L + E+ED L+ T +T++ A+D +ET S
Sbjct: 1145 EKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALD--------EETRS 1196
Query: 754 TIKDNSEIHHKCTSDMETILTFIPQFHR----LNDSIQTLVNDNQRYNFVLQVAKTLAGI 809
E+ K +E + + QF R L+ + QTL +N +A L +
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKEN------ADLAGELRVL 1250
Query: 810 PRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFETRLQDIESKV 869
+ ++ + +K+ E S+ ++ + L +K+ ++ L + E K
Sbjct: 1251 GQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKA 1310
Query: 870 TQTLIPYYISVKKGSVVTNERDQALQLQVLNSRFKALEAKSIHLSINFFSLNKTLHEVLT 929
+ L S+ T E Q Q LN + K L SL L E +
Sbjct: 1311 IK-LAKDVASLSSQLQDTQELLQEETRQKLN-----VSTKLRQLEEERNSLQDQLDEEME 1364
Query: 930 MCHNASTSVSELNATI---PKWIKHSLPDIQLLQKGLTEFVEPIIQIKTQ 976
N +S LN + K ++ ++ L++G F + I + Q
Sbjct: 1365 AKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Score = 51.6 bits (122), Expect = 5e-06
Identities = 115/667 (17%), Positives = 260/667 (38%), Gaps = 123/667 (18%)
Query: 281 QLRAQEQQSLIHTNQAESHTAVGRGVAEQQQQQGCGDPEVMQKMTDQVNYQAMKLTLLQK 340
+LRA+ +Q + T + + + E+ + E+ QK V +L ++
Sbjct: 1174 ELRAKREQEV---------TVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKR 1224
Query: 341 KIDNISLTVNDVRNTYSSLEGKVS---------EDKSREFQSLLKGLKSK---------S 382
N+ + + L G++ E K ++ ++ ++ L+SK
Sbjct: 1225 AKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAE 1284
Query: 383 INVLIRDIVREQFKI--FQNDMQETVAQLFKTVSSLSEDLESTRQIIQKVNESVVSIAAQ 440
+N + + E + N+ + +L K V+SLS L+ T++++Q+ ++++
Sbjct: 1285 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVST- 1343
Query: 441 QKFVLVQENRPTLTDIVE--------LRNHIVNVRQEMTLTCEK------PIKELEVKQT 486
K ++E R +L D ++ L HI + +++ + +K ++ LE +
Sbjct: 1344 -KLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKK 1402
Query: 487 HLEGALE---QEHSRSILYYESLNKTLSKLKEV------------------------HEQ 519
+ +E Q++ Y+ L KT ++L++ +Q
Sbjct: 1403 RFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQ 1462
Query: 520 LLSTEQ-----VSDQKNAPAAE---------SVSNNVTEYMSTLHENIKKQSLMMLQMFE 565
LL+ E+ +D+++ AE S++ + E + E +++ + M+ E
Sbjct: 1463 LLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA-KEELERTNKMLKAEME 1521
Query: 566 DLHIQESKINNLTVSLEMEKESLRGECEDMLSKCRNDFKFQLKDTEENLHVLNQTLAEVL 625
DL + + LE K +L + E+M K QL++ E+ L Q +
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRALETQMEEM--------KTQLEELEDEL----QATEDAK 1569
Query: 626 FPMDNKMDKMSEQLNDLTYDMEILQPLLEQGASLRQTMTYEQPKEAIVIRKKIENLTSAV 685
++ M + Q D++ E+ Q +E E RK+ +A
Sbjct: 1570 LRLEVNMQALKGQFE---RDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAK 1626
Query: 686 NSLNFIIKELTKRHNLLRNEVQGRDDA------LERRINEYALEMEDGLNKTMTIINNAI 739
L +K+L + + + ++GR++A L+ ++ ++ E+ED I A
Sbjct: 1627 KKLEGDLKDLELQAD---SAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAK 1683
Query: 740 DFIQDNYALKETLSTIKDNSEIHHKCTSDMETILTFIPQFHRLNDSIQTLVNDNQRYNFV 799
+ + +L+ L ++++ + + + + + S + + D +R
Sbjct: 1684 ENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKR---- 1739
Query: 800 LQVAKTLAGIPRDEKLNQSNFQKMYQMFNETTSQVRKYQQNMSHLEEKLLLTTKISKNFE 859
++ +A + + + Q N + M + +VRK Q L +L ++ E
Sbjct: 1740 -RLEARIAQLEEELEEEQGNMEAM-------SDRVRKATQQAEQLSNELATERSTAQKNE 1791
Query: 860 TRLQDIE 866
+ Q +E
Sbjct: 1792 SARQQLE 1798
Score = 42.0 bits (97), Expect = 0.004
Identities = 55/248 (22%), Positives = 107/248 (43%), Gaps = 30/248 (12%)
Query: 359 LEGKVSEDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVA---QLFKTVSS 415
LEG + +D + S +KG + ++I L + ++ Q K FQ ++++ A ++F T
Sbjct: 1629 LEGDL-KDLELQADSAIKG-REEAIKQLRK--LQAQMKDFQRELEDARASRDEIFATAKE 1684
Query: 416 LSEDLESTRQIIQKVNESVVSI--AAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLT 473
+ +S + ++ E + + A +Q + +E L + RN + + +
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEK------ 1738
Query: 474 CEKPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQL---LSTEQVSDQK 530
+ LE + LE LE+E E+++ + K + EQL L+TE+ + QK
Sbjct: 1739 -----RRLEARIAQLEEELEEEQGNM----EAMSDRVRKATQQAEQLSNELATERSTAQK 1789
Query: 531 NAPAAESVSNNVTEYMSTLHENIKKQSLMMLQMFEDLHIQESKINNLTVSLEMEKESLRG 590
N A + + E S LHE + + + + E+KI L +E E +
Sbjct: 1790 NESARQQLERQNKELRSKLHE---MEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQA 1846
Query: 591 ECEDMLSK 598
+ + K
Sbjct: 1847 ATKSLKQK 1854
Score = 35.0 bits (79), Expect = 0.44
Identities = 45/174 (25%), Positives = 78/174 (44%), Gaps = 26/174 (14%)
Query: 357 SSLEGKVS-EDKSREFQSLLKGLKSKSINVLIRDIVREQFKIFQNDMQETVAQLFKTVSS 415
SSL G+ + +D+ R ++ + L+ ++ EQ + M + V + +
Sbjct: 1726 SSLSGRNALQDEKRRLEARIAQLEE--------ELEEEQGNM--EAMSDRVRKATQQAEQ 1775
Query: 416 LSEDLESTRQIIQKVNESVVSIAAQQKFVLVQENRPTLTDIVELRNHIVNVRQEMTLTCE 475
LS +L + R QK NES A QQ L ++N+ ELR+ + + + +
Sbjct: 1776 LSNELATERSTAQK-NES----ARQQ---LERQNK-------ELRSKLHEMEGAVKSKFK 1820
Query: 476 KPIKELEVKQTHLEGALEQEHSRSILYYESLNKTLSKLKEVHEQLLSTEQVSDQ 529
I LE K LE +EQE +SL + KLKE+ Q+ ++++Q
Sbjct: 1821 STIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQ 1874
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,227,856
Number of Sequences: 37866
Number of extensions: 1837104
Number of successful extensions: 11215
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 123
Number of HSP's successfully gapped in prelim test: 590
Number of HSP's that attempted gapping in prelim test: 8907
Number of HSP's gapped (non-prelim): 2529
length of query: 1228
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1114
effective length of database: 13,930,794
effective search space: 15518904516
effective search space used: 15518904516
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.