Guide to the Human Genome
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Search of human proteins with 4508017

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
         (478 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]          1015   0.0  
gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]        1004   0.0  
gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]          929   0.0  
gi|160707881 formin 2 [Homo sapiens]                                  103   4e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]    102   1e-21
gi|163965366 nascent polypeptide-associated complex alpha subuni...    96   5e-20
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 96   7e-20
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ...    89   9e-18
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [...    89   9e-18
gi|146134388 YLP motif containing 1 [Homo sapiens]                     85   2e-16
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    84   3e-16
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ...    83   5e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    82   1e-15
gi|55750053 atrophin-1 [Homo sapiens]                                  81   2e-15
gi|55750041 atrophin-1 [Homo sapiens]                                  81   2e-15
gi|116284392 mucin 2 precursor [Homo sapiens]                          79   9e-15
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               79   1e-14
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    78   2e-14
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    78   2e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    77   3e-14
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              77   4e-14
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    76   6e-14
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       75   1e-13
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    75   1e-13
gi|150170670 piccolo isoform 2 [Homo sapiens]                          75   1e-13
gi|150378539 piccolo isoform 1 [Homo sapiens]                          75   1e-13
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         74   3e-13
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    74   4e-13
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    74   4e-13
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    74   4e-13

>gi|4508017 zinc finger protein 207 isoform a [Homo sapiens]
          Length = 478

 Score = 1015 bits (2624), Expect = 0.0
 Identities = 478/478 (100%), Positives = 478/478 (100%)

Query: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
           MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60

Query: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
           TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
           MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT
Sbjct: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240

Query: 241 ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
           ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV
Sbjct: 241 ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300

Query: 301 GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
           GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT
Sbjct: 301 GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360

Query: 361 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRP 420
           SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRP
Sbjct: 361 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRP 420

Query: 421 PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY 478
           PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY
Sbjct: 421 PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGRY 478


>gi|148612835 zinc finger protein 207 isoform c [Homo sapiens]
          Length = 494

 Score = 1004 bits (2597), Expect = 0.0
 Identities = 478/494 (96%), Positives = 478/494 (96%), Gaps = 16/494 (3%)

Query: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
           MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60

Query: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
           TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180

Query: 181 MPPG----------------MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 224
           MPPG                MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA
Sbjct: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240

Query: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 284
           QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA
Sbjct: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 300

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
           LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA
Sbjct: 301 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 360

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 404
           ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG
Sbjct: 361 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 420

Query: 405 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 464
           MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP
Sbjct: 421 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 480

Query: 465 MGMRPPVMSQGGRY 478
           MGMRPPVMSQGGRY
Sbjct: 481 MGMRPPVMSQGGRY 494


>gi|73808090 zinc finger protein 207 isoform b [Homo sapiens]
          Length = 463

 Score =  929 bits (2401), Expect = 0.0
 Identities = 445/494 (90%), Positives = 445/494 (90%), Gaps = 47/494 (9%)

Query: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60
           MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE
Sbjct: 1   MGRKKKKQLKPWCWYCNRDFDDEKILIQHQKAKHFKCHICHKKLYTGPGLAIHCMQVHKE 60

Query: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120
           TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD
Sbjct: 61  TIDAVPNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDD 120

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG
Sbjct: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180

Query: 181 MPPG----------------MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 224
           MPPG                MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA
Sbjct: 181 MPPGLHHQRKYTQSFCGENIMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQA 240

Query: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 284
           QAVSAPGILNRPPAPTATVPAPQPPVTKPLFP                            
Sbjct: 241 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFP---------------------------- 272

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
              S  QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA
Sbjct: 273 ---SAGQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 329

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 404
           ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG
Sbjct: 330 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 389

Query: 405 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 464
           MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP
Sbjct: 390 MMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 449

Query: 465 MGMRPPVMSQGGRY 478
           MGMRPPVMSQGGRY
Sbjct: 450 MGMRPPVMSQGGRY 463


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score =  103 bits (256), Expect = 4e-22
 Identities = 119/382 (31%), Positives = 146/382 (38%), Gaps = 76/382 (19%)

Query: 129  PQPVQPQQGYIPPMAQPG-----LPPVPGAPGMPPGIPPLMPGV----PPLMPG----MP 175
            P P  P  G  PP   PG     LPP+PGA G+PP  PP +PG     PP +PG    +P
Sbjct: 911  PPPPLPGAGIPPPPPLPGAGILPLPPLPGA-GIPP--PPPLPGAAIPPPPPLPGAGIPLP 967

Query: 176  PVMPGM---PPGMMPMGGMMP----PGPGIPPLMP----GMPPGMPPPVPRPGIPPMTQA 224
            P +PG    PP  +P  G+ P    PG GIPP  P    G+PP  PPP+P  GIPP    
Sbjct: 968  PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPP---P 1022

Query: 225  QAVSAPGILNRPPAPTATVPAPQP------PVTKPLFPSAGQMGTPVTSSSTASSNSESL 278
              +   GI   PP P A +P P P      P   PL P AG +  P             L
Sbjct: 1023 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL-PGAG-IPPPPPLPGAGIPPPPPL 1080

Query: 279  SASSKALFPSTAQAQAAVQGPV-GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 337
              +     P    A      P+ G    P    P     PP P                 
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPL---------------- 1124

Query: 338  STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP-IGN 396
                 P A I   P            I P   +         P     +P P   P  G 
Sbjct: 1125 -----PGAGIPPPP------PLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGI 1173

Query: 397  PPVGPIGGM-MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
            PP  P+ G+ +PP P +P   G+  P PP     G     P  LPG   P    PP+ PP
Sbjct: 1174 PPPPPLPGVGIPPPPPLP---GVGIPPPP--PLPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228

Query: 456  YQGGPPRPPMGMR-PPVMSQGG 476
              G PP P + +  PP++ Q G
Sbjct: 1229 GTGIPPPPLLPVSGPPLLPQVG 1250



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 65/161 (40%), Positives = 78/161 (48%), Gaps = 35/161 (21%)

Query: 129  PQPVQPQQGYIPPMAQPGL-----PPVPGAPGMPPGIPPLMP--GVPPLMPGMPPVMPGM 181
            P P  P  G  PP   PG      PP+PGA G+PP  PP +P  G+PP     PP +PG 
Sbjct: 1109 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-GIPP--PPPLPRVGIPP-----PPPLPGA 1160

Query: 182  ---PPGMMPMGGMMPPGP----GIPPLMP----GMPPGMPPPVPRPGIPPMTQAQAVSAP 230
               PP  +P  G+ PP P    GIPP  P    G+PP  PPP+P  GIPP         P
Sbjct: 1161 GIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPP--PPPLPGAGIPP-----PPPLP 1213

Query: 231  GILNRPPAPTATVPAPQPPV-TKPLFPSAGQMGTPVTSSST 270
            G +  PPAP   +P P   +   PL P +G    P   SST
Sbjct: 1214 G-MGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSST 1253



 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 103/351 (29%), Positives = 126/351 (35%), Gaps = 66/351 (18%)

Query: 143  AQPGL----PPVPGAPGMP-PGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMP---- 193
            + PGL    PP P  PGM  P +P      PP + G   + P  PP  +P  G+ P    
Sbjct: 869  SMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPP--PPPPLPGAGIPPPPPL 926

Query: 194  PGPGIPPLMPGMPPGMPPPVPRPG--IPPMTQAQAVSAPGILNRPPAPTATVPAPQP--- 248
            PG GI PL P    G+PPP P PG  IPP      +   GI   PP P A +P P P   
Sbjct: 927  PGAGILPLPPLPGAGIPPPPPLPGAAIPP---PPPLPGAGIPLPPPLPGAGIPPPPPLPG 983

Query: 249  ---PVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV-GTDF 304
               P   PL P AG +  P             L  +     P    A      P+ G   
Sbjct: 984  AGIPPPPPL-PGAG-IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1041

Query: 305  KPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLI 364
             P    P     PP P                      P A I   P            I
Sbjct: 1042 PPPPPLPGAGIPPPPPL---------------------PGAGIPPPP------PLPGAGI 1074

Query: 365  HPDEDISLEERRAQLPKYQRNLPRPGQAP-IGNPPVGPI-GGMMPPQPGIPQQQGMRPPM 422
             P   +         P     +P P   P +G PP  P+ G  +PP P +P   G+ PP 
Sbjct: 1075 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLP-GAGIPPPP 1133

Query: 423  PPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM---GMRPP 470
            P  G       G+P   P  +P  G  PP   P  G PP PP+   G+ PP
Sbjct: 1134 PLPG------AGIPP--PPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPP 1176



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 57/144 (39%), Positives = 74/144 (51%), Gaps = 30/144 (20%)

Query: 129  PQPVQPQQGYIPPMAQPGL-----PPVPGAPGMPPGIPPLMPGV----PPLMPGMPPVMP 179
            P P  P+ G  PP   PG      PP+PGA G+PP  PP +PGV    PP +PG+     
Sbjct: 1142 PPPPLPRVGIPPPPPLPGAGIPPPPPLPGA-GIPP--PPPLPGVGIPPPPPLPGV----- 1193

Query: 180  GMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRP--GIPPMTQAQAVSAPGILNRPP 237
            G+PP     G  +PP P +P +  G+PP   PP+P P  GIPP      VS P +L  P 
Sbjct: 1194 GIPPPPPLPGAGIPPPPPLPGM--GIPPAPAPPLPPPGTGIPP-PPLLPVSGPPLL--PQ 1248

Query: 238  APTATVPAPQ------PPVTKPLF 255
              ++T+P PQ      PP+   LF
Sbjct: 1249 VGSSTLPTPQVCGFLPPPLPSGLF 1272



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 89/334 (26%), Positives = 110/334 (32%), Gaps = 68/334 (20%)

Query: 171  MPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGM------------PPGM--------- 209
            +P  PP+        MP  GM+PP P  PPL PGM            PP +         
Sbjct: 855  IPSPPPLPCTESSSSMPGLGMVPPPP--PPL-PGMTVPTLPSTAIPQPPPLQGTEMLPPP 911

Query: 210  PPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ--PPVTKPLFPSAGQMGTPVTS 267
            PPP+P  GIPP      +   GIL  PP P A +P P   P    P  P     G P+  
Sbjct: 912  PPPLPGAGIPP---PPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPP 968

Query: 268  SSTASSNSESLSASSKALFPSTAQAQAAVQGP---VGTDFKPLNSTPATTTEPPKPTFPA 324
                +            + P      A +  P    G    P    P     PP P    
Sbjct: 969  PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL--- 1025

Query: 325  YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 384
                              P A I   P            I P   +         P    
Sbjct: 1026 ------------------PGAGIPPPP------PLPGAGIPPPPPLPGAGIPPPPPLPGA 1061

Query: 385  NLPRPGQAP-IGNPPVGPI-GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY-LPG 441
             +P P   P  G PP  P+ G  +PP P +P   G+ PP P  G        +PG  +P 
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP-GAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120

Query: 442  AMPPYGQGPPMVPPYQGG-----PPRPPMGMRPP 470
              P  G G P  PP  G      PP P +G+ PP
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPP 1154



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 77/291 (26%), Positives = 106/291 (36%), Gaps = 43/291 (14%)

Query: 198  IPPL--MPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN---RPPAPTATVPAPQPPVTK 252
            +PP+  +PG PP  P     P     ++   + +P  ++       PT ++  P PP + 
Sbjct: 757  LPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSL 816

Query: 253  PLFPSAGQMGT-PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTP 311
                  GQ G+ P  S ST    S   S SS   F ++    +    P     +  +S P
Sbjct: 817  LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSA--FKNSCNIPSPPPLPCT---ESSSSMP 871

Query: 312  AT-TTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 370
                  PP P  P  T  T  +T+       +    +   P  L           P   I
Sbjct: 872  GLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGI 931

Query: 371  SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPI-GGMMPPQPGIPQQQGMRPPMPPHGQYG 429
                           LP P     G PP  P+ G  +PP P +P   G   P+PP     
Sbjct: 932  ---------------LPLPPLPGAGIPPPPPLPGAAIPPPPPLP---GAGIPLPPPLPGA 973

Query: 430  GHHQGMPGYLPGA-MPPY----GQGPPMVPPYQGG--PPRPPM---GMRPP 470
            G     P  LPGA +PP     G G P  PP  G   PP PP+   G+ PP
Sbjct: 974  GIPPPPP--LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 33/96 (34%), Positives = 41/96 (42%), Gaps = 18/96 (18%)

Query: 129  PQPVQPQQGYIPPMAQPGL--PPVPGAPGMPPGI----PPLMP-GVPPLMPGM------- 174
            P P  P  G  PP   PG+  PP P  P  PPG     PPL+P   PPL+P +       
Sbjct: 1197 PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPT 1256

Query: 175  PPVM----PGMPPGMMPMGGMMPPGPGIPPLMPGMP 206
            P V     P +P G+  +G     G    P+ P  P
Sbjct: 1257 PQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRP 1292



 Score = 33.1 bits (74), Expect = 0.57
 Identities = 64/287 (22%), Positives = 94/287 (32%), Gaps = 75/287 (26%)

Query: 76  ELEIYGMEGIPEK-----DMDERRRLLEQKTQESQKKKQQDDSDEY---DDDDSAASTSF 127
           + +IY      E+     D+ +  RL +Q+ Q+ Q + QQ    +     ++ +A  T+ 
Sbjct: 180 DTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAV 239

Query: 128 QPQP-----------------------------------------VQPQQGYIPPMAQPG 146
            PQP                                          +P++   PP   PG
Sbjct: 240 SPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPP--SPG 297

Query: 147 LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPG-PGIPPLMPGM 205
             PV  AP +P   P             P   PG      P+ G       G        
Sbjct: 298 GLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDA 357

Query: 206 PPGMP-----PPV-----PRPGIPPMTQAQAVSAPGILNRP--PAPTATVPAPQPPVTKP 253
           P G P     P V      R G  P  +AQ   AP   + P  PAP+     P P +T P
Sbjct: 358 PRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLIT-P 416

Query: 254 LF--PSAGQMGTPVTSSSTASSNS--------ESLSASSKALFPSTA 290
            +   +  Q+ +P  S S + + S         SLS  S+    S A
Sbjct: 417 CYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVA 463


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score =  102 bits (253), Expect = 1e-21
 Identities = 113/378 (29%), Positives = 129/378 (34%), Gaps = 58/378 (15%)

Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPP---GIPPLMPGVPPLMPGMPPV------- 177
           +PQ   PQ G  P     G PP PG P  PP   G  P  P  P    G PP        
Sbjct: 56  KPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSP 111

Query: 178 --MPGMPPGMMPMGGMMPPGPGIPPLMPGMPP--------GMPPPVPRPGIPPMTQAQAV 227
              PG P G  P GG  P GP  PP  P  PP        G PPP    G PP    ++ 
Sbjct: 112 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171

Query: 228 SA---PGILNRPPAPTATVP-APQPPVTKPLFPSAGQMGTPV-------TSSSTASSNSE 276
           S+   PG    PP      P  P PP  KP  P       P                +++
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 277 SLSASSKALFPSTAQAQAA--VQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTS 334
           S SA S    P     Q     QGP     KP    P    +P  P  P   Q       
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291

Query: 335 TTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI 394
           + + ++  P       P              P      +       K Q   P+ G  P 
Sbjct: 292 SKSRSSRSPPGKPQGPP--------------PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 337

Query: 395 GNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHG---QYGGHHQGMPGYLPGAMPPYGQGPP 451
           G PP G   G  PPQ G   +    PP  P G   Q G + QG P    G  P   Q PP
Sbjct: 338 GPPPPGKPQGP-PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPA-GGNPQQPQAPP 395

Query: 452 MVPPYQGGPPRPPMGMRP 469
              P   GPPRPP G RP
Sbjct: 396 AGQPQ--GPPRPPQGGRP 411



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 104/369 (28%), Positives = 122/369 (33%), Gaps = 50/369 (13%)

Query: 110 QDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
           Q+ +++   ++S +  +  PQ   PQ G  P             P  PPG P   P    
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQ-----------GPPSPPGKPQGPPPQGG 65

Query: 170 LMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPP-------PVPRPGIPPMT 222
             P  PP  PG P G  P GG  P GP  PP  PG P G PP       P   PG P   
Sbjct: 66  NQPQGPPPPPGKPQGPPPQGGNKPQGP--PP--PGKPQGPPPQGDKSRSPRSPPGKPQGP 121

Query: 223 QAQAVSAPGILNRPPAPTATVPAPQPP-VTKPLF-PSAGQMGTPVTSSSTASSNSESLSA 280
             Q  + P     PP P      P P    KP   P  G+   P       S +S S   
Sbjct: 122 PPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPG 178

Query: 281 SSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTA 340
             +   P   Q     QGP     KP    P    +P  P  P   Q         + +A
Sbjct: 179 KPQGPPP---QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSA 235

Query: 341 AKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVG 400
             P       P              P      +       K Q   P+ G  P G PP G
Sbjct: 236 RSPPGKPQGPP--------------PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG 281

Query: 401 PIGGMMPPQPGIPQQQGMRPPMPPHG---QYGGHHQG--MPGYLPGAMPPYGQGPPMVPP 455
              G  PPQ G   +    PP  P G   Q G   QG   P   P   PP G   P  PP
Sbjct: 282 KPQG-PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340

Query: 456 YQGGPPRPP 464
             G P  PP
Sbjct: 341 PPGKPQGPP 349



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 77/302 (25%), Positives = 86/302 (28%), Gaps = 59/302 (19%)

Query: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234
           P ++ G P G  P GG  P GP  PP  P  PP      P+   PP         PG   
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPP---------PGKPQ 79

Query: 235 RPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA 294
            PP      P   PP  KP        G P     + S  S       K   P   Q   
Sbjct: 80  GPPPQGGNKPQGPPPPGKP-------QGPPPQGDKSRSPRSPP----GKPQGPPP-QGGN 127

Query: 295 AVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL 354
             QGP     KP    P    +P  P  P   Q         + ++  P       P   
Sbjct: 128 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP-- 185

Query: 355 TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ 414
                                  Q     +  P P   P G PP G      PP PG PQ
Sbjct: 186 -----------------------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 222

Query: 415 QQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 474
                   PP G         P   P   PP G   P  PP       PP G       Q
Sbjct: 223 GP------PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP-------PPPGKPQGPPPQ 269

Query: 475 GG 476
           GG
Sbjct: 270 GG 271



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 58/170 (34%), Positives = 63/170 (37%), Gaps = 27/170 (15%)

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPP---- 176
           SA S   +PQ   PQ G   P   P  P  P  P    G  P  P  P    G PP    
Sbjct: 234 SARSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 292

Query: 177 ------VMPGMPPGMMPMGGMMPPGPGIPPLMPGMPP--------GMPPPVPRPGIPPMT 222
                   PG P G  P GG  P GP  PP  P  PP        G PPP    G PP  
Sbjct: 293 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 352

Query: 223 QAQAVSA---PGILNRPPAPTATVP-APQPPV----TKPLFPSAGQMGTP 264
            +++ SA   PG    PP      P  P PP      +P  P AGQ   P
Sbjct: 353 GSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP 402



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 41/120 (34%), Positives = 44/120 (36%), Gaps = 20/120 (16%)

Query: 121 SAASTSFQPQPVQPQ-----QGYIPPMAQPGLPPVPGA--------PGMPPGIPPL---- 163
           S+ S   +PQ   PQ     QG  PP  +P  PP  G         PG P G PP     
Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355

Query: 164 --MPGVPPLMPGMPPVMPGM-PPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPP 220
                 PP  P  PP   G  P G  P  G  P  P  PP      P  PP   RP  PP
Sbjct: 356 SRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 45/136 (33%), Positives = 54/136 (39%), Gaps = 18/136 (13%)

Query: 359 ATSKLIHPDEDISLEERRAQL-------PKYQRNLPRPGQAPIGNPP-VGPIGGMMP--- 407
           A S   + +ED+S EE  + +       P    N P+   +P G P    P GG  P   
Sbjct: 12  ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71

Query: 408 -PQPGIPQ----QQGMRP--PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGP 460
            P PG PQ    Q G +P  P PP    G   QG     P + P   QGPP     Q   
Sbjct: 72  PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 131

Query: 461 PRPPMGMRPPVMSQGG 476
           P PP G       QGG
Sbjct: 132 PPPPPGKPQGPPPQGG 147


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 96.3 bits (238), Expect = 5e-20
 Identities = 101/372 (27%), Positives = 125/372 (33%), Gaps = 45/372 (12%)

Query: 123  ASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP--PLMPGMPPVMPG 180
            AS S +  P  P      P   P  P    AP  P   PP   G P  P   G P     
Sbjct: 932  ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA 991

Query: 181  MPPGMMPMGGMMPPGPGIPPLMPGMPP----GMPPPVPRP--------GIPPMTQAQAVS 228
             PP   P GG   P P   P  P + P    G P   P P          PP  +    +
Sbjct: 992  TPPS--PKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA 1049

Query: 229  APGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
             P     P  P AT+P+P+     P  PS     TP  ++  +     +  +   A  P 
Sbjct: 1050 TPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106

Query: 289  TAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASIT 348
             A   +   G      K   +TPA T  PP P     T       +T  +T   P   + 
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAAT--PPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1164

Query: 349  SKP--ATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI--GNPPVGPIGG 404
            + P     TT +AT                   PK     P P  AP      P  P GG
Sbjct: 1165 TPPPKGAPTTPAAT----------------PPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208

Query: 405  MMPPQP-GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 463
            +  P P G P      PP P  G      +G P   P A PP  +G P  PP +G P   
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGPATPPPKGAP--T 1265

Query: 464  PMGMRPPVMSQG 475
            P    PP +  G
Sbjct: 1266 PPAATPPSLKGG 1277



 Score = 92.4 bits (228), Expect = 8e-19
 Identities = 104/376 (27%), Positives = 124/376 (32%), Gaps = 44/376 (11%)

Query: 131  PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPL-----MPGMPPVMPGMPPGM 185
            P  P      P   P  P   GAP  P   PP   G P        P  P V P  P G 
Sbjct: 963  PTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGS 1022

Query: 186  MPMGGMMPPGPGIPPLM-PGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
             P     P G   PP   P  P G P   P P   P T A  + +P      PA  +   
Sbjct: 1023 -PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP---KGGPATPSLKG 1078

Query: 245  APQPPVTKPLFPSAGQM-----GTPVTSSSTASSNSESLSA-------SSKALFPSTAQA 292
            AP PP   P  P  G       G P+  ++T  S    L+        ++ A  P + + 
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138

Query: 293  QAAVQGPVGTDFKPLNSTPAT----TTEPPK--PTFPAYTQSTAS---TTSTTNSTAAKP 343
              A   P G    P  + P+      T PPK  PT PA T  +      T +       P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 344  AASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI---GNPPVG 400
            AA+  S    L T S       P             PK     P P  AP      PP  
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTP-------AATPPSPKGGLATPSPKGAPTTPAATPPSP 1251

Query: 401  PIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAM-PPYGQGPPMVPPYQGG 459
              G   PP  G P      PP    G     H+G P   P  + PP  +G P   P +G 
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN--PAVVTPPSPKGGPATSPPKGA 1309

Query: 460  PPRPPMGMRPPVMSQG 475
            P  P      P  S G
Sbjct: 1310 PTPPAATPPSPKGSPG 1325



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 93/349 (26%), Positives = 114/349 (32%), Gaps = 73/349 (20%)

Query: 131  PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP--PLMPGMPPVMPGMPPGMMPM 188
            P  P      P   P  P + GAP  P   PP   G P  P   G P      PP   P 
Sbjct: 1057 PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS--PK 1114

Query: 189  GGMM-PPGPGIPPLMPGMPP----GMPPPVPRPGIPPMTQAQAVSAP--GILNRPPAPTA 241
            GG+  PP  G P      PP    G+  P P+    P T A    +P  G+   PP    
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA--PTTPAATPPSPKGGLATPPPKGAP 1172

Query: 242  TVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVG 301
            T PA  PP  K    +    G P T ++T                P + +   A   P G
Sbjct: 1173 TTPAATPPSPKGGLATPSPKGAPTTPAAT----------------PPSPKGGLATPSPKG 1216

Query: 302  TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 361
                   +TPA T  PP P     T S     +T  +T   P     + P          
Sbjct: 1217 AP-----TTPAAT--PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPP---------- 1259

Query: 362  KLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP 421
                                  +  P P   P   PP    G   PP  G P    + PP
Sbjct: 1260 ---------------------PKGAPTP---PAATPPSLKGGLATPPHKGAPNPAVVTPP 1295

Query: 422  MPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 470
             P  G      +G P   P A PP  +G P  PP +G P   P  + PP
Sbjct: 1296 SPKGGPATSPPKGAP-TPPAATPPSPKGSPGTPPPKGAP--TPPAVTPP 1341



 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 93/364 (25%), Positives = 112/364 (30%), Gaps = 38/364 (10%)

Query: 121  SAASTSFQPQPVQPQQGY--IPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVM 178
            S    SF P+     QG    P       PP P     P  + PL P    L P   P  
Sbjct: 829  SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPT- 887

Query: 179  PGMPPGMMPMGGMMPPGPGIPPLM---------------PGMPPGMPPPVPRPGIPPMTQ 223
            P +     P  G   P P   P +               P   P  P P   P  P  T 
Sbjct: 888  PSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP 947

Query: 224  AQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSK 283
                  P   +   APT     P  P   P  PS     TP  ++  +     +  +   
Sbjct: 948  PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG 1007

Query: 284  ALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP 343
            A  P      +    P  T F    STP   T P     PA T       +T  +T   P
Sbjct: 1008 APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP 1067

Query: 344  AASITSKPATLTTTSA-TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI--GNPPVG 400
                   PAT +   A T     P             PK     P P  AP+     P  
Sbjct: 1068 KGG----PATPSLKGAPTPPAATPPS-----------PKGGPATPSPKGAPMPPAATPPS 1112

Query: 401  PIGGM-MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGG 459
            P GG+  PP  G P      PP P  G      +G P   P A PP  +G    PP +G 
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAATPPSPKGGLATPPPKGA 1171

Query: 460  PPRP 463
            P  P
Sbjct: 1172 PTTP 1175



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 96/371 (25%), Positives = 121/371 (32%), Gaps = 61/371 (16%)

Query: 140  PPMAQPGL--PPVPGAPGMPPGIPPLMPG--VPPLMPGMPPVMPGMPPGMMPMGGMMPP- 194
            PP  + GL  P   GAP  P   PP   G    P   G P      PP   P GG+  P 
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS--PKGGLATPS 1236

Query: 195  ---GPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVT 251
                P  P   P  P G P   P  G P    A   S  G L  PP       AP P V 
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK----GAPNPAVV 1292

Query: 252  KPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTP 311
             P  P  G    P TS    +    + +  S    P T   + A             + P
Sbjct: 1293 TPPSPKGG----PATSPPKGAPTPPAATPPSPKGSPGTPPPKGA------------PTPP 1336

Query: 312  ATTTEPPK--PTFPAYTQST--ASTTSTTNSTAAKPAASITSKPATLTTTSATSK---LI 364
            A T   PK  PT PA T S+    TT ++      PAA+ + K     T  +  +   + 
Sbjct: 1337 AVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396

Query: 365  HPDED------ISLEERRA-QLPKYQRNLPRPGQAPIGNPPVGPI-------------GG 404
             P  D      I L  ++A   P  +     P +  +  P V P+             G 
Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456

Query: 405  MMPPQPGIPQQQGMRPPMP--PHGQYGGHHQGMPGYLPGAMPPYGQG--PPMVPPYQGGP 460
              P   G P    + PP P  P           P   P    P G    P ++P      
Sbjct: 1457 ATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV 1516

Query: 461  PRPPMGMRPPV 471
            P  P   R P+
Sbjct: 1517 PATPSSRRDPI 1527



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 103/414 (24%), Positives = 134/414 (32%), Gaps = 75/414 (18%)

Query: 123  ASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG---VPPLMPG------ 173
            A+ S +  P  P      P   P  PP  GAP  P   PP + G    PP          
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292

Query: 174  MPPVMPGMPPGMMPMGGMMPPG--PGIPPLMPGMPP--GMP-PPVPRPGIPPMTQAQAVS 228
             PP   G P    P G   PP   P  P   PG PP  G P PP   P  P  T     +
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352

Query: 229  APGILNRPPAPTATVPAPQPPVTKP-------LFPSAGQMGTPVTSSSTASSNSESLSAS 281
             P     P  P++    P PP   P       + P + + G P   S      S ++   
Sbjct: 1353 TPSSKGGPTTPSSK-EGPTPPAATPSHKGGPAMTPPSPKRG-PAIPSPKGDPTSPAVIPL 1410

Query: 282  SKALFPSTAQAQAAVQGPVGTDFKPLNSTP-----ATTTEPPK-----------PTFPAY 325
            S    P+T   +     P   D  P   TP     A  T  PK           PT PA 
Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAV 1470

Query: 326  TQST---------ASTTSTTNSTAAKPA--------ASITSKPATLTTT--------SAT 360
            T  +          +T+S+     A PA        A I S P  +  T        + T
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP-IGNP---PVGPIGGMMPPQPGIPQQQ 416
            + L+      +L  + A +P     +P P + P I  P   P  P        P +    
Sbjct: 1531 ATLLSKKTPATLAPKEALIPP-AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPST 1589

Query: 417  GMRPPMP-----PHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 465
                P P     P        +  P   P   PP  +  P  P  +G P  PP+
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAP-TPPAVTPPSPEKGPATPAPKGTPTSPPV 1642



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 85/356 (23%), Positives = 130/356 (36%), Gaps = 26/356 (7%)

Query: 129  PQPVQPQQGYIPPMAQ-------PGLPPVPGAPGMPPGIPPLMPGV--PPLMPGMP-PVM 178
            P  + P++  IPP          P +P    AP  P       P    P    G P P  
Sbjct: 1539 PATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598

Query: 179  PGMPPGMM-PMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 237
              +PP +  P     P  P + P  P   P  P P   P  PP+T +    +P     P 
Sbjct: 1599 LLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP---TSPA 1655

Query: 238  APTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ 297
            + T  + A  P  +K L    G         + A  ++  ++A ++   P T ++ +A  
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK-GPQTKKS-SATS 1713

Query: 298  GPVGTDFKPLN-STPATTTEPPKPTFPAYTQSTASTTSTTNSTAAK-PAASITSKPATLT 355
             P+  D    N S    +T  P P  P    S+ +      S + K P A   SK +T  
Sbjct: 1714 PPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPL 1773

Query: 356  TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQ 415
            T +A  K++   E  S+    +  P    +LP    AP   P + P    +P  PG+  +
Sbjct: 1774 TAAAFEKVLPKPESASV----SAAPSPPVSLP---LAPSPVPTLPPKQQFLPSSPGLVLE 1826

Query: 416  QGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 471
               + P+ P  +        P  + G +P       M  P   G P P    + PV
Sbjct: 1827 SPSK-PLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 77/300 (25%), Positives = 101/300 (33%), Gaps = 45/300 (15%)

Query: 200 PLMPGMPPGMP-PPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTK------ 252
           PL+P      P  P P+    P+  A  V AP I    P+P+   PA  PP TK      
Sbjct: 699 PLVPTASENCPVAPSPQNTCAPL--ATLVLAPEIPKSVPSPSLP-PAGTPPGTKKVDGIS 755

Query: 253 ---PLFPSAGQMGTPVTSSSTASSNSES---------------LSASSKALFPSTAQAQA 294
               L P A       T  S AS+ + S               +S S +   P T +  A
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA 815

Query: 295 AVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL 354
               P+G    P++   A+       +F     S A+T S T      P+      P+ +
Sbjct: 816 GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT-----PPSPKGAPTPSAV 870

Query: 355 TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI----------GNPPVGPIGG 404
           T  S     + P E  +        PK     P P QAP                 P G 
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930

Query: 405 MMPPQP-GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 463
              P P G P      PP P  G      +  P   P A PP  +G P  P  +G P  P
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-TPPAATPPSPKGGPATPSPKGAPTPP 989



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 83/336 (24%), Positives = 114/336 (33%), Gaps = 42/336 (12%)

Query: 156  MPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGM-----MPPGPGIPPLMPGMPPGMP 210
            + P IP  +P      P +PP   G PPG   + G+     + P    P   P    G  
Sbjct: 726  LAPEIPKSVPS-----PSLPPA--GTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778

Query: 211  PPVPRPG----IPPMTQAQAVSAPGILNRPPAPTATVPAPQPPV---TKPLFPSAGQMGT 263
                  G    +        VS      RPP    +   P  P+   + P+ P       
Sbjct: 779  ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSA-GPDTPIGNLSSPVSPVEASFLP 837

Query: 264  PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ--GPVGTDFKPLNS-TPATTTEP-PK 319
              + S   S +S + + S     P  A   +AV    P G    P  + TP+    P PK
Sbjct: 838  ENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK 897

Query: 320  --PTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA-TSKLIHPDEDISLEERR 376
              P  PA  Q+ A + ++++   A+   +    PA+ +   A T     P          
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS-------- 949

Query: 377  AQLPKYQRNLPRPGQAPI--GNPPVGPIGGMMPPQP-GIPQQQGMRPPMPPHGQYGGHHQ 433
               PK     P P  AP      P  P GG   P P G P      PP P  G      +
Sbjct: 950  ---PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006

Query: 434  GMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRP 469
            G P   P   PP  +G P   P+  G   PP    P
Sbjct: 1007 GAP-TPPAVTPPSPKGSPAATPFPKGASTPPAATPP 1041



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 55/247 (22%), Positives = 95/247 (38%), Gaps = 26/247 (10%)

Query: 142  MAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPL 201
            + +P    V  AP  PP   PL P   P +P     +P  P       G++   P   PL
Sbjct: 1782 LPKPESASVSAAPS-PPVSLPLAPSPVPTLPPKQQFLPSSP-------GLVLESPS-KPL 1832

Query: 202  MPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQM 261
             P     + P +P   I      Q+V    ++N P   +A +P P P   +P+  +    
Sbjct: 1833 APADEDELLPLIPPEPISGGVPFQSV----LVNMPTPKSAGIPVPTPSAKQPVTKNNKGS 1888

Query: 262  GTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPT 321
            GT   S  +     E  S  +     +T QAQ A    +  D +P++    + +E  K  
Sbjct: 1889 GTESDSDESVPELEEQDSTQA-----TTQQAQLAAAAEI--DEEPVSKAKQSRSE-KKAR 1940

Query: 322  FPAYTQSTASTTSTTNST--AAKPAASITSKPATLTTTSATSKLIHPD---EDISLEERR 376
                       T  T  T   +K    + +KP    + ++ + ++  +   ED+S + + 
Sbjct: 1941 KAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQL 2000

Query: 377  AQLPKYQ 383
            A   K++
Sbjct: 2001 AAAEKFK 2007



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 56/279 (20%), Positives = 96/279 (34%), Gaps = 33/279 (11%)

Query: 141 PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPP 200
           P A    P  P  P         +P  PPL    P  +  +P  ++           +P 
Sbjct: 480 PAALVMAPVAPKEPSTQVATTLRIPVSPPLPD--PEDLKNLPSSVLVKFPTQKDLQTVPA 537

Query: 201 LMPGMP--PGMPPPVPR--PGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFP 256
            + G P  P       +  P + P+ QA   ++P          +T  +P+ P++     
Sbjct: 538 SLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSF-------QSTSSSPEIPLSPEATL 590

Query: 257 SAGQMGTPVTSSSTASSNSESLSASSKA-LFPSTAQAQAAVQGPVGTDFKPLNSTPATTT 315
           +   +G P+     ASS +  L  +S A +  + + A     GP+    K    TP    
Sbjct: 591 AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPL---LKSSLITPTVAA 647

Query: 316 EPPKPTFPAYTQSTASTTSTTNSTAAKP----------------AASITSKPATLTTTSA 359
            P +   PA    T +  ++T +T A P                  ++T+ P   T +  
Sbjct: 648 FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707

Query: 360 TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPP 398
                 P    +        P+  +++P P   P G PP
Sbjct: 708 CPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPP 746



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 59/241 (24%), Positives = 82/241 (34%), Gaps = 29/241 (12%)

Query: 123  ASTSFQPQPVQPQQGYIPPMAQ--PGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
            A TS  P+         PP  +  P  P   G P  PP  P  +    P  P       G
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD-SPTSPASVTCKMG 1662

Query: 181  MPPGMMPMGGMMPPGP-GIPPLMPGMPPGMPPPVPRPGIP-PMTQAQAVSAPGILNRPPA 238
                    G     GP  +  ++    P   P +  P    P T+  + ++P I   P A
Sbjct: 1663 ATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722

Query: 239  ------PTATV-PAPQPPVTKPLFPSA-GQMGTPVTSSSTASSNSESLSASSKALF---- 286
                  P +TV PAP  PV K    +A G+  +       A   S++ +  + A F    
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782

Query: 287  --PSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
              P +A   AA   PV     P           P PT P   Q   S+      + +KP 
Sbjct: 1783 PKPESASVSAAPSPPVSLPLAP----------SPVPTLPPKQQFLPSSPGLVLESPSKPL 1832

Query: 345  A 345
            A
Sbjct: 1833 A 1833



 Score = 36.6 bits (83), Expect = 0.052
 Identities = 54/207 (26%), Positives = 79/207 (38%), Gaps = 19/207 (9%)

Query: 202 MPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQM 261
           +P     +P P     + PM+ A +V+A      P  P    PAPQ     PL  SA   
Sbjct: 9   VPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQ---QCPL--SAANQ 63

Query: 262 GTPVTSSSTASSNSESL----SASSKALFPSTA-QAQAAVQGPVGTDFKP----LNSTPA 312
            +P  S ST +S    +    S+S  AL   TA +A   +   +G    P    L S   
Sbjct: 64  ASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMI 123

Query: 313 TTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISL 372
             T    P+  A     A    +   ++A P   +TS P+     S +  +I     I+ 
Sbjct: 124 APTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGS--VITLSAPIAP 181

Query: 373 EERRAQLPKYQRN-LPRPGQAPIGNPP 398
            E +  L K     +P P   P  +PP
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTP--SPP 206



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 62/303 (20%), Positives = 101/303 (33%), Gaps = 30/303 (9%)

Query: 141 PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPP 200
           P+  P  P       +P G  P  P   P + G PP+ P       PM         I P
Sbjct: 77  PLEVP-FPQSSSGTALPLGTAPEAPTFLPNLIG-PPISPAALALASPM---------IAP 125

Query: 201 LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQ 260
            + G P    P       P   Q  +   P +L  PP+           ++ P+ PS  +
Sbjct: 126 TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185

Query: 261 MGTPVTSSSTASS--NSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPP 318
                  S    +   + S       +        A++Q  V +      +TP TT    
Sbjct: 186 TNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVAS---LPQTTPTTTLAIA 242

Query: 319 KP-----TFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL----IHPDED 369
            P     T  +   S  +  S +      P A+++    +L   +++ K       PD  
Sbjct: 243 SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFP 302

Query: 370 ISLEERRAQLPKYQ----RNLPRPGQAPIGNPPVGPIG-GMMPPQPGIPQQQGMRPPMPP 424
           ISL    A L +      + L + G + + +P V  I           P Q+ + PP+P 
Sbjct: 303 ISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPS 362

Query: 425 HGQ 427
             +
Sbjct: 363 RNE 365



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 55/249 (22%), Positives = 84/249 (33%), Gaps = 36/249 (14%)

Query: 141 PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGM---PPGMMPMGGMMPPGPG 197
           P  +  +PP+P    + P      P V P +   P  +  +   P G + +       P 
Sbjct: 351 PSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPT 410

Query: 198 IP-------------PLMPGMPPGMPPPVPRPGIPPMTQAQA--------------VSAP 230
                          PL+  MP       P     P T A A              +S+ 
Sbjct: 411 TSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSG 470

Query: 231 GILN-RPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPST 289
            I N  P +P A V AP  P  +P    A  +  PV+       + ++L +S    FP+ 
Sbjct: 471 PISNIEPTSPAALVMAPVAP-KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQ 529

Query: 290 AQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS 349
              Q     P   +  P +   A  T    PT     Q+    + +  ST++ P   + S
Sbjct: 530 KDLQTV---PASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL-S 585

Query: 350 KPATLTTTS 358
             ATL   S
Sbjct: 586 PEATLAKKS 594


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 95.9 bits (237), Expect = 7e-20
 Identities = 78/244 (31%), Positives = 108/244 (44%), Gaps = 37/244 (15%)

Query: 103 ESQKKKQQDDSDEYDDDDSAASTSFQ---PQPVQPQQGYIPPMAQP---GLPPVPGA--P 154
           E++K+ Q+   +E   D ++ ++S Q   PQ V P Q   PPM  P   G PP P    P
Sbjct: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424

Query: 155 GMPPGIPP-LMPGVPPLM--PGMPPVM--------PGMPPGMMPMGGMMPPGPGIPPLMP 203
           G P G+PP   PG PP +  PGMP +         PG PPG  P G    P PG+PP  P
Sbjct: 425 GPPTGLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPG-RPPGPPPGPPPGLPPGPP 483

Query: 204 --GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQM 261
             G PP +PPP P PGIPP         PG++ RPP      PAP         P+ G +
Sbjct: 484 PRGPPPRLPPPAP-PGIPP-------PRPGMM-RPPLVPPLGPAPPGLFPPAPLPNPGVL 534

Query: 262 GTPVT------SSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTT 315
             P        +  T+++  E  + ++ +  P     +A +   V T  +        T 
Sbjct: 535 SAPPNLIQRPKADDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATA 594

Query: 316 EPPK 319
            P +
Sbjct: 595 APQR 598



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 74/268 (27%), Positives = 101/268 (37%), Gaps = 49/268 (18%)

Query: 97  LEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGM 156
           + ++ +E ++  + DD D+ DD ++   +  Q +      G     +Q   PP       
Sbjct: 342 IPEEGREVEEFSEDDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPP------- 394

Query: 157 PPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMG---GMMP-PGPGIPPLM--PGMP---- 206
              +PP     PP MPG PP+ P   P + P G   G+ P P PG PP +  PGMP    
Sbjct: 395 -QSVPPSQIQAPP-MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGAPPFLRPPGMPGLRG 452

Query: 207 --PGMPPPVPRPGIPPMTQAQAVSAPGILNRPP--APTATVPAPQPPVTKPLFPSAGQMG 262
             P + PP P PG PP         PG+   PP   P   +P P PP   P  P  G M 
Sbjct: 453 PLPRLLPPGPPPGRPP--GPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPP--PRPGMMR 508

Query: 263 TPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPK--P 320
            P+            L  +   LFP        V            S P    + PK   
Sbjct: 509 PPLV---------PPLGPAPPGLFPPAPLPNPGVL-----------SAPPNLIQRPKADD 548

Query: 321 TFPAYTQSTASTTSTTNSTAAKPAASIT 348
           T  A  +  A+ T +       P A IT
Sbjct: 549 TSAATIEKKATATISAKPQITNPKAEIT 576



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 31/139 (22%)

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP------- 408
           T++A+S+   P + +   + +A         P PG  P+G PP  P+    PP       
Sbjct: 383 TSTASSQQQAPPQSVPPSQIQAP--------PMPGPPPLGPPPAPPLRPPGPPTGLPPGP 434

Query: 409 ---------QPGIPQQQG----MRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
                     PG+P  +G    + PP PP G+  G   G P  LP   PP G  P + PP
Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494

Query: 456 YQGG--PPRPPMGMRPPVM 472
              G  PPRP M MRPP++
Sbjct: 495 APPGIPPPRPGM-MRPPLV 512



 Score = 38.1 bits (87), Expect = 0.018
 Identities = 75/346 (21%), Positives = 113/346 (32%), Gaps = 41/346 (11%)

Query: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPP--GPGIPPLM---- 202
           P+P  P  P  I  L+  +P  +PG  P     P  +       PP     I PL+    
Sbjct: 140 PLPDMPHAPSNI--LIQDIP--LPGAQP-----PSILKKTSAYGPPTRAVSILPLLGHGV 190

Query: 203 PGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMG 262
           P +PPG  PP P PG PP    Q      +  R       +P  +        P   Q G
Sbjct: 191 PRLPPGRKPPGPPPGPPPPQVVQ------MYGRKVGFALDLPPRRRDEDMLYSPELAQRG 244

Query: 263 --TPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKP 320
               V+S+S      E +           +    +     G +F   ++      E  K 
Sbjct: 245 HDDDVSSTSEDDGYPEDMDQDKHDDSTDDSDTDKSDGESDGDEFVHRDNGERDNNEEKKS 304

Query: 321 TFPA--YTQSTASTTSTTNSTAAKPAASITSK------PATLTTTSATSKLIHPDEDISL 372
                       S     N     P  ++  +      P         S+    D+    
Sbjct: 305 GLSVRFADMPGKSRKKKKNMKELTPLQAMMLRMAGQEIPEEGREVEEFSEDDDEDDSDDS 364

Query: 373 EERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ---PGIPQQQGMRPPMPPHGQYG 429
           E  +    +++      G +   +    P   + P Q   P +P    + PP  P  +  
Sbjct: 365 EAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPP 424

Query: 430 GHHQGMPGYLPGAMPPYGQGPPMVPPYQGG-----PPRPPMGMRPP 470
           G   G+P   P   PP+ + PP +P  +G      PP PP G RPP
Sbjct: 425 GPPTGLPPGPPPGAPPFLR-PPGMPGLRGPLPRLLPPGPPPG-RPP 468



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 30/108 (27%), Positives = 44/108 (40%), Gaps = 7/108 (6%)

Query: 369 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP--MPPHG 426
           ++  E++RAQL +Y   +       + + P+      MP  P     Q +  P   PP  
Sbjct: 111 EVEYEQKRAQLSQYFDAVKNAQHVEVESIPLPD----MPHAPSNILIQDIPLPGAQPPSI 166

Query: 427 QYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 474
                  G P      +P  G G P +PP +  PP PP G  PP + Q
Sbjct: 167 LKKTSAYGPPTRAVSILPLLGHGVPRLPPGR-KPPGPPPGPPPPQVVQ 213



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/120 (25%), Positives = 46/120 (38%), Gaps = 24/120 (20%)

Query: 99  QKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPP 158
           +K +   ++K+   S  +D   +A     +  P+ P   + P        P+PGA   PP
Sbjct: 108 RKLEVEYEQKRAQLSQYFDAVKNAQHVEVESIPL-PDMPHAPSNILIQDIPLPGA--QPP 164

Query: 159 GIPPLMPGVPP------LMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPP 212
            I        P      ++P +   +P +PPG  P               PG PPG PPP
Sbjct: 165 SILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKP---------------PGPPPGPPPP 209


>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
           [Homo sapiens]
          Length = 1132

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 103/390 (26%), Positives = 135/390 (34%), Gaps = 68/390 (17%)

Query: 107 KKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG 166
           KK +++  +    +++ +    P P +P    +PP+  P    VP     PP +PP  PG
Sbjct: 620 KKPENEVAQNGGAETSHTEPVSPIP-KPLPVPVPPIPVPAPITVP-----PPQVPPHQPG 673

Query: 167 VPPLMPGMPPVMPGM-PPGMMPMGGMMPP--GPGIPPLMPGMPPGMPPPVPRPGIPPMTQ 223
                   PPV+  + PP   P  G+ PP  GPG+P      PP  PPP  RPG  PM  
Sbjct: 674 --------PPVVGALQPPAFTPPLGIPPPGFGPGVP------PPPPPPPFLRPGFNPMHL 719

Query: 224 AQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSK 283
                 PG    PP P     +  PP T P+          + +S+ A  N ++    S 
Sbjct: 720 PPGFLPPG----PPPPITPPVSIPPPHTPPI---------SIPNSTIAGINEDTTKDLSI 766

Query: 284 ALFPSTAQAQAAVQGPVGTDFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAA 341
                T  + A      G   K   S   PA  T  P P             S   +   
Sbjct: 767 GNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP-------PVTQPVSLLGTQGV 819

Query: 342 KPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGP 401
            P   I  +  +     A   LI       +     Q        P P       PP GP
Sbjct: 820 APGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 879

Query: 402 IGGMMPPQPGIPQQQGMRPPMPPHGQY----GGHHQGMPGYLPGA-----------MPPY 446
            G  MPP        GM+ P PPHG +    G    G PG  PG              P 
Sbjct: 880 GGFAMPP------PHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 933

Query: 447 GQGPPMVP--PYQGGPPRPPMGMRPPVMSQ 474
            Q  P  P  P Q    +PP   +PP   Q
Sbjct: 934 QQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 963



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 103/364 (28%), Positives = 128/364 (35%), Gaps = 102/364 (28%)

Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           +  A TS   +PV P    IP      +PP+P  P  P  +PP  P VPP  PG P V  
Sbjct: 629 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 679

Query: 180 GMPPGMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 237
             PP   P  G+ PPG  PG+PP      P  PPP  RPG  PM        PG    PP
Sbjct: 680 LQPPAFTPPLGIPPPGFGPGVPP------PPPPPPFLRPGFNPMHLPPGFLPPG----PP 729

Query: 238 APTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ 297
            P     +  PP T P+          + +S+ A  N ++    S      T  + A   
Sbjct: 730 PPITPPVSIPPPHTPPI---------SIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGN 780

Query: 298 GPVGTDFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLT 355
              G   K   S   PA  T  P P                            ++P +L 
Sbjct: 781 AESGDSVKMYGSAVPPAAPTNLPTPP--------------------------VTQPVSLL 814

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PG 411
            T   +    P   I L     Q P       RPG  P+  PP     GM PP     P 
Sbjct: 815 GTQGVA----PGPVIGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPL 860

Query: 412 IPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 471
           +P +     PMPPH  + G             PP G G   +PP        P GM+ P 
Sbjct: 861 MPPR-----PMPPHMMHRG-------------PPPGPGGFAMPP--------PHGMKGPF 894

Query: 472 MSQG 475
              G
Sbjct: 895 PPHG 898



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 45/120 (37%), Positives = 50/120 (41%), Gaps = 19/120 (15%)

Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGG 190
           P+ P +   P M   G PP PG   MPP  P  M G  P  P  P V PG  PG+   GG
Sbjct: 859 PLMPPRPMPPHMMHRGPPPGPGGFAMPP--PHGMKG--PFPPHGPFVRPGGMPGL---GG 911

Query: 191 MMPPGPGIPPLMP------GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
              PGPG  P  P        PP  P   P+P  P   Q Q    P    +PP PT   P
Sbjct: 912 ---PGPG--PGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPP-PTQQQP 965



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 64/260 (24%), Positives = 93/260 (35%), Gaps = 55/260 (21%)

Query: 249 PVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLN 308
           PV + +  + G    PV  SS   + +   S  +    PS+    A  Q    T  + L 
Sbjct: 128 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 187

Query: 309 STPATTTEPPKPTFPAYTQS----TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLI 364
               T  +PPKP  PA   +      + T+   +T  +P+    + P     T+   KL+
Sbjct: 188 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 247

Query: 365 ----HPDEDISLEERR-------------AQLPKYQRNLPRPGQAPIG---NPPVGPIG- 403
               + DE  ++EE +             A +P           AP      PP  P G 
Sbjct: 248 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 307

Query: 404 -GMMPPQPGIPQQQGM-----------------RPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            G    QP   Q Q M                 + P+PP+GQ       MPG+     PP
Sbjct: 308 PGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ-------MPGFGLLPTPP 360

Query: 446 YGQGPPMVPPYQGGPPRPPM 465
           +   PPM  P    PP PP+
Sbjct: 361 F---PPMAQPVI--PPTPPV 375



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 27/144 (18%)

Query: 98  EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
           EQKT   +K   + D D+  +       +D+ A T+  P    P      +P  A P   
Sbjct: 237 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 296

Query: 148 -PPVPGAPGMPPGIPPLMPGVP---------PLMPG-----MPPVMPGMPPGMMPMGGMM 192
            PP P AP   PG     P            P M G     M   +P  P G MP  G++
Sbjct: 297 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 356

Query: 193 PPGPGIPPLMPGMPPGMPPPVPRP 216
           P  P  P   P +PP   PPV +P
Sbjct: 357 PTPPFPPMAQPVIPP--TPPVQQP 378



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 1/43 (2%)

Query: 222 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTP 264
           T A   +AP     PPAPTATVPA   P      P     G P
Sbjct: 267 TTAVTTTAPAAAV-PPAPTATVPAAAAPAAASPPPPQAPFGFP 308


>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
           [Homo sapiens]
          Length = 1147

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 103/390 (26%), Positives = 135/390 (34%), Gaps = 68/390 (17%)

Query: 107 KKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG 166
           KK +++  +    +++ +    P P +P    +PP+  P    VP     PP +PP  PG
Sbjct: 635 KKPENEVAQNGGAETSHTEPVSPIP-KPLPVPVPPIPVPAPITVP-----PPQVPPHQPG 688

Query: 167 VPPLMPGMPPVMPGM-PPGMMPMGGMMPP--GPGIPPLMPGMPPGMPPPVPRPGIPPMTQ 223
                   PPV+  + PP   P  G+ PP  GPG+P      PP  PPP  RPG  PM  
Sbjct: 689 --------PPVVGALQPPAFTPPLGIPPPGFGPGVP------PPPPPPPFLRPGFNPMHL 734

Query: 224 AQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSK 283
                 PG    PP P     +  PP T P+          + +S+ A  N ++    S 
Sbjct: 735 PPGFLPPG----PPPPITPPVSIPPPHTPPI---------SIPNSTIAGINEDTTKDLSI 781

Query: 284 ALFPSTAQAQAAVQGPVGTDFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAA 341
                T  + A      G   K   S   PA  T  P P             S   +   
Sbjct: 782 GNPIPTVVSGARGNAESGDSVKMYGSAVPPAAPTNLPTP-------PVTQPVSLLGTQGV 834

Query: 342 KPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGP 401
            P   I  +  +     A   LI       +     Q        P P       PP GP
Sbjct: 835 APGPVIGLQAPSTGLLGARPGLIPLQRPPGMPPPHLQRFPLMPPRPMPPHMMHRGPPPGP 894

Query: 402 IGGMMPPQPGIPQQQGMRPPMPPHGQY----GGHHQGMPGYLPGA-----------MPPY 446
            G  MPP        GM+ P PPHG +    G    G PG  PG              P 
Sbjct: 895 GGFAMPP------PHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQ 948

Query: 447 GQGPPMVP--PYQGGPPRPPMGMRPPVMSQ 474
            Q  P  P  P Q    +PP   +PP   Q
Sbjct: 949 QQPQPQAPQQPQQQQQQQPPPSQQPPPTQQ 978



 Score = 79.3 bits (194), Expect = 7e-15
 Identities = 103/364 (28%), Positives = 128/364 (35%), Gaps = 102/364 (28%)

Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           +  A TS   +PV P    IP      +PP+P  P  P  +PP  P VPP  PG P V  
Sbjct: 644 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 694

Query: 180 GMPPGMMPMGGMMPPG--PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP 237
             PP   P  G+ PPG  PG+PP      P  PPP  RPG  PM        PG    PP
Sbjct: 695 LQPPAFTPPLGIPPPGFGPGVPP------PPPPPPFLRPGFNPMHLPPGFLPPG----PP 744

Query: 238 APTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ 297
            P     +  PP T P+          + +S+ A  N ++    S      T  + A   
Sbjct: 745 PPITPPVSIPPPHTPPI---------SIPNSTIAGINEDTTKDLSIGNPIPTVVSGARGN 795

Query: 298 GPVGTDFKPLNST--PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLT 355
              G   K   S   PA  T  P P                            ++P +L 
Sbjct: 796 AESGDSVKMYGSAVPPAAPTNLPTPP--------------------------VTQPVSLL 829

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PG 411
            T   +    P   I L     Q P       RPG  P+  PP     GM PP     P 
Sbjct: 830 GTQGVA----PGPVIGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPL 875

Query: 412 IPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 471
           +P +     PMPPH  + G             PP G G   +PP        P GM+ P 
Sbjct: 876 MPPR-----PMPPHMMHRG-------------PPPGPGGFAMPP--------PHGMKGPF 909

Query: 472 MSQG 475
              G
Sbjct: 910 PPHG 913



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 45/120 (37%), Positives = 50/120 (41%), Gaps = 19/120 (15%)

Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGG 190
           P+ P +   P M   G PP PG   MPP  P  M G  P  P  P V PG  PG+   GG
Sbjct: 874 PLMPPRPMPPHMMHRGPPPGPGGFAMPP--PHGMKG--PFPPHGPFVRPGGMPGL---GG 926

Query: 191 MMPPGPGIPPLMP------GMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
              PGPG  P  P        PP  P   P+P  P   Q Q    P    +PP PT   P
Sbjct: 927 ---PGPG--PGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPP-PTQQQP 980



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 64/260 (24%), Positives = 93/260 (35%), Gaps = 55/260 (21%)

Query: 249 PVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLN 308
           PV + +  + G    PV  SS   + +   S  +    PS+    A  Q    T  + L 
Sbjct: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202

Query: 309 STPATTTEPPKPTFPAYTQS----TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLI 364
               T  +PPKP  PA   +      + T+   +T  +P+    + P     T+   KL+
Sbjct: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262

Query: 365 ----HPDEDISLEERR-------------AQLPKYQRNLPRPGQAPIG---NPPVGPIG- 403
               + DE  ++EE +             A +P           AP      PP  P G 
Sbjct: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 322

Query: 404 -GMMPPQPGIPQQQGM-----------------RPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            G    QP   Q Q M                 + P+PP+GQ       MPG+     PP
Sbjct: 323 PGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ-------MPGFGLLPTPP 375

Query: 446 YGQGPPMVPPYQGGPPRPPM 465
           +   PPM  P    PP PP+
Sbjct: 376 F---PPMAQPVI--PPTPPV 390



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 27/144 (18%)

Query: 98  EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
           EQKT   +K   + D D+  +       +D+ A T+  P    P      +P  A P   
Sbjct: 252 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 311

Query: 148 -PPVPGAPGMPPGIPPLMPGVP---------PLMPG-----MPPVMPGMPPGMMPMGGMM 192
            PP P AP   PG     P            P M G     M   +P  P G MP  G++
Sbjct: 312 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371

Query: 193 PPGPGIPPLMPGMPPGMPPPVPRP 216
           P  P  P   P +PP   PPV +P
Sbjct: 372 PTPPFPPMAQPVIPP--TPPVQQP 393



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 1/43 (2%)

Query: 222 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTP 264
           T A   +AP     PPAPTATVPA   P      P     G P
Sbjct: 282 TTAVTTTAPAAAV-PPAPTATVPAAAAPAAASPPPPQAPFGFP 323


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 84.7 bits (208), Expect = 2e-16
 Identities = 105/368 (28%), Positives = 148/368 (40%), Gaps = 65/368 (17%)

Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGI-PPLMPG-VPPLMPGM-PPVMPGMPPGM 185
           P P  P     PP+  P +PP    P +PP + PP +P  VPP  PGM PPVMP   P  
Sbjct: 517 PPPFVPYSQMPPPL--PTMPPPVLPPSLPPPVMPPALPATVPP--PGMPPPVMPPSLPTS 572

Query: 186 MPMGGMMP--PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATV 243
           +P  GM P     G PP++P  PP +    P P +PP     + + P ++  PP  +AT 
Sbjct: 573 VPPPGMPPSLSSAGPPPVLP--PPSLSSAGPPPVLPP-PSLSSTAPPPVMPLPPLSSATP 629

Query: 244 P--APQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVG 301
           P   P P V + + P       P  SSS +S   E       AL P+          PV 
Sbjct: 630 PPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEK---PRPALLPT----------PVS 676

Query: 302 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 361
                  S P TT  PP     +   S    +    S +A P +S +S      +++A S
Sbjct: 677 -----FGSAPPTTYHPP---LQSAGPSEQVNSKAPLSKSALPYSSFSSDQGLGESSAAPS 728

Query: 362 KLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGP----------IGGMMP-PQP 410
           + I   +D+ +             LP P ++     P GP          +G     P+P
Sbjct: 729 QPITAVKDMPVRSGGL--------LPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRP 780

Query: 411 GIPQQQGMRPPMPPHGQYGGH----HQGMPGYLP--GAMPPYGQGPPMVPPYQGGP---- 460
             P+ +G RP   P  +Y GH     +   G +P   A   Y      + P Q GP    
Sbjct: 781 KGPRFEGNRPD-GPRPRYEGHPAEGTKSKWGMIPRGPASQFYITPSTSLSPRQSGPQWKG 839

Query: 461 PRPPMGMR 468
           P+P  G +
Sbjct: 840 PKPAFGQQ 847



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 88/381 (23%), Positives = 133/381 (34%), Gaps = 105/381 (27%)

Query: 124 STSFQPQPVQPQQGYIPPMAQPG-------LPPVPGAPGM-------------------- 156
           S+ + P PV P      P A PG        P  P + G                     
Sbjct: 11  SSHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQK 70

Query: 157 -------PPGIPPLMPGVPPLMPGMPPVMPG--------MPPGMMPMGGMMPPGP----- 196
                  P  +PP     PPL P  PPVMPG         PP M P     PPGP     
Sbjct: 71  QMQCVLQPHHLPP-----PPLPP--PPVMPGGGYGDWQPPPPPMPP-----PPGPALSYQ 118

Query: 197 ------------------GIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPA 238
                             G+ P+    PP  PP  P   +PP         P     PP 
Sbjct: 119 KQQQYKHQMLHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178

Query: 239 PTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQG 298
            +     P  P      PS   +  P  S S++SS+S+S  + S++  PS   +QA+   
Sbjct: 179 SSQPYLPPAQPSPSQSPPSQSYL-APTPSYSSSSSSSQSYLSHSQSYLPS---SQASPSR 234

Query: 299 PVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAS----TTSTTNSTAAKPAASITSKPATL 354
           P          + +    PP P+ P   ++T       +   N +  +  A+    P+T+
Sbjct: 235 P------SQGHSKSQLLAPPPPSAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTM 288

Query: 355 TTTSATSKLIHPDEDISLEER-RAQLPKYQ------RNLPRPGQAPIGNPPVGPI----G 403
            T     +  +    +SL++R +  LP ++      ++ P P +  +  P    +     
Sbjct: 289 -TPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPS 347

Query: 404 GMMPPQPGIPQQQGMRPPMPP 424
              PP P  P  + + PP+PP
Sbjct: 348 SEEPPLP--PPNEEVPPPLPP 366



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 73/296 (24%), Positives = 106/296 (35%), Gaps = 30/296 (10%)

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPG-MPPPVPRPGIPPMTQAQAVSAPGILNRPPAP 239
           MPP  +P   M PP       +P MPP  +PP +P P +PP   A  V  PG+   PP  
Sbjct: 516 MPPPFVPYSQMPPP-------LPTMPPPVLPPSLPPPVMPPALPA-TVPPPGM--PPPVM 565

Query: 240 TATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP 299
             ++P   PP   P  PS    G P      + S++            STA        P
Sbjct: 566 PPSLPTSVPPPGMP--PSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPP 623

Query: 300 VGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL----- 354
           + +   P    P    +   P   A     AS +S ++    KP  ++   P +      
Sbjct: 624 LSSATPPPGIPPPGVPQGIPPQLTAAPVPPAS-SSQSSQVPEKPRPALLPTPVSFGSAPP 682

Query: 355 TTTSATSKLIHPDEDISLEE--RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGI 412
           TT     +   P E ++ +    ++ LP Y       G       P  PI  +      +
Sbjct: 683 TTYHPPLQSAGPSEQVNSKAPLSKSALP-YSSFSSDQGLGESSAAPSQPITAV----KDM 737

Query: 413 PQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYG---QGP-PMVPPYQGGPPRPP 464
           P + G   P PP   Y    +G     P      G   +GP P  P ++G  P  P
Sbjct: 738 PVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGP 793



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 50/183 (27%), Positives = 67/183 (36%), Gaps = 36/183 (19%)

Query: 311 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 370
           P     PP    P  +     ++STT      PAA  +S   +         L    +  
Sbjct: 16  PPPVPPPPPVALPEASPGPGYSSSTT------PAAPSSSGFMSFRE----QHLAQLQQLQ 65

Query: 371 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGM---MPPQPGIPQQQGMRPPMPPHGQ 427
            + +++ Q      +LP P   P+  PPV P GG     PP P +P   G         Q
Sbjct: 66  QMHQKQMQCVLQPHHLPPP---PLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQ 122

Query: 428 YGG---HHQ--GMPGYLPGAMPPYGQGPPMVPPYQGG-----------PPRPPMGMRPPV 471
           Y     HHQ  G PG +P  +    + PP  PP   G           PP+PP    PP 
Sbjct: 123 YKHQMLHHQRDGPPGLVPMEL----ESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPT 178

Query: 472 MSQ 474
            SQ
Sbjct: 179 SSQ 181



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 40/121 (33%), Positives = 43/121 (35%), Gaps = 24/121 (19%)

Query: 379 LPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPP-MPPHGQYGGHHQGMPG 437
           +P  Q   P P   P   PP  P   M P  P      GM PP MPP         GMP 
Sbjct: 521 VPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPP 580

Query: 438 YLPGAMPP--------YGQGPPMV-----------PPYQGGPP----RPPMGMRPPVMSQ 474
            L  A PP           GPP V           PP    PP     PP G+ PP + Q
Sbjct: 581 SLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPPPGVPQ 640

Query: 475 G 475
           G
Sbjct: 641 G 641



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 43/160 (26%), Positives = 57/160 (35%), Gaps = 35/160 (21%)

Query: 133  QPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMM 192
            +PQ     P  +  L      PGM P         PP     PP M G PPG +      
Sbjct: 1482 EPQMADHLPPQESRLQNTSSRPGMYP---------PPGSYRPPPPM-GKPPGSIVRPSAP 1531

Query: 193  PPGPGIPPLMPGMP-PGMPPPVPRPGIPPMTQAQAVSA-------------------PGI 232
            P    +P   P +P P  PPP P P  PP+ + Q  +                     G+
Sbjct: 1532 PARSSVPVTRPPVPIPPPPPPPPLPPPPPVIKPQTSAVEQERWDEDSFYGLWDTNDEQGL 1591

Query: 233  LNRPPAPTATVPA----PQPPVTKPLFPSAG-QMGTPVTS 267
             +   + TA +P+    P PPV   + P     MG P  S
Sbjct: 1592 NSEFKSETAAIPSAPVLPPPPVHSSIPPPGPVPMGMPPMS 1631



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 48/192 (25%), Positives = 68/192 (35%), Gaps = 42/192 (21%)

Query: 88   KDMDERRRLLEQKTQESQKKKQQDDSDEYD----DDDSAASTSFQPQPVQPQQGYIPPMA 143
            K   E + L EQK Q  + K    +    D     +    +TS +P    P   Y PP  
Sbjct: 1458 KAAQELKMLREQKEQLQKMKDFGSEPQMADHLPPQESRLQNTSSRPGMYPPPGSYRPP-- 1515

Query: 144  QPGLPPVPGAPG--MPPGIPPLMPGVPPLMPGMP----PVMPGMPPGMMPMGGMMPPGPG 197
                PP+   PG  + P  PP    VP   P +P    P  P +P          PP P 
Sbjct: 1516 ----PPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPPPPPPPPLP----------PPPPV 1561

Query: 198  IPPLMPGMPP---------GMPPPVPRPGIPPMTQAQAVSAPG--ILNRPPA-----PTA 241
            I P    +           G+       G+    +++  + P   +L  PP      P  
Sbjct: 1562 IKPQTSAVEQERWDEDSFYGLWDTNDEQGLNSEFKSETAAIPSAPVLPPPPVHSSIPPPG 1621

Query: 242  TVPAPQPPVTKP 253
             VP   PP++KP
Sbjct: 1622 PVPMGMPPMSKP 1633



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 52/223 (23%), Positives = 74/223 (33%), Gaps = 38/223 (17%)

Query: 231 GILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTA 290
           G  + PP P   VP P P       P  G      +S++ A+ +S    +  +       
Sbjct: 10  GSSHYPPPP---VPPPPPVALPEASPGPGYS----SSTTPAAPSSSGFMSFREQHLAQLQ 62

Query: 291 QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK 350
           Q Q   Q  +    +P +  P     PP P  P                   PA S   +
Sbjct: 63  QLQQMHQKQMQCVLQPHHLPPPPL--PPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQ 120

Query: 351 PATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP--IGNPPVGPIGGMMPP 408
                                 ++ + Q+  +QR+ P PG  P  + +PP  P    +PP
Sbjct: 121 ----------------------QQYKHQMLHHQRDGP-PGLVPMELESPPESP---PVPP 154

Query: 409 QPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 451
              +P  Q   PP  P   Y       P YLP A P   Q PP
Sbjct: 155 GSYMPPSQSYMPPPQPPPSYYPPTSSQP-YLPPAQPSPSQSPP 196



 Score = 33.5 bits (75), Expect = 0.44
 Identities = 30/96 (31%), Positives = 36/96 (37%), Gaps = 26/96 (27%)

Query: 378  QLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP-GIPQQQGMRPPMPPHGQYGGHHQGMP 436
            Q  + Q    RPG  P       P G   PP P G P    +RP  PP            
Sbjct: 1492 QESRLQNTSSRPGMYP-------PPGSYRPPPPMGKPPGSIVRPSAPP----------AR 1534

Query: 437  GYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 472
              +P   PP     P+ PP    PP PP+   PPV+
Sbjct: 1535 SSVPVTRPPV----PIPPP----PPPPPLPPPPPVI 1562



 Score = 32.3 bits (72), Expect = 0.97
 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 5/70 (7%)

Query: 406  MPPQPGIPQQQGMRPPM-PPHGQYGGHHQ--GMPGYL--PGAMPPYGQGPPMVPPYQGGP 460
            +PPQ    Q    RP M PP G Y         PG +  P A P     P   PP    P
Sbjct: 1489 LPPQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPPVPIPP 1548

Query: 461  PRPPMGMRPP 470
            P PP  + PP
Sbjct: 1549 PPPPPPLPPP 1558



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 21/88 (23%), Positives = 27/88 (30%), Gaps = 7/88 (7%)

Query: 379 LPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY 438
           +P  Q  +P P   P   PP      + P QP   Q    +  + P   Y         Y
Sbjct: 158 MPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSY 217

Query: 439 LPGAMPPYGQGPPMVPPYQGGPPRPPMG 466
           L             +P  Q  P RP  G
Sbjct: 218 L-------SHSQSYLPSSQASPSRPSQG 238



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 5/36 (13%)

Query: 150  VPGAPGMPPGIPPLMPGVPPLMP---GMPPVMPGMP 182
            +P AP +PP  PP+   +PP  P   GMPP+    P
Sbjct: 1602 IPSAPVLPP--PPVHSSIPPPGPVPMGMPPMSKPPP 1635


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 84.0 bits (206), Expect = 3e-16
 Identities = 103/387 (26%), Positives = 145/387 (37%), Gaps = 55/387 (14%)

Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPP-----LMPGVPPLMP-- 172
           D   S  F P  ++  Q        P  PP     G PP + P     +M G PP     
Sbjct: 7   DGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPP 66

Query: 173 -GMPPVMPGMPPGMMPMGGMMPP-GP---GIPPLMPGMPPGMPPP---VPRPGIPPMTQA 224
            G PP  P MPP M P GG+ PP GP     PP MP     MPPP   +  PG+PP+T  
Sbjct: 67  FGRPPFDPNMPP-MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAP 125

Query: 225 QAVSAP-----GILNRPP--------APTATVPAPQPPVTK--------PLFPSAGQMGT 263
              + P      + N+ P        A T      +P   K        P+  +  Q+  
Sbjct: 126 GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185

Query: 264 PVTSSSTASSNSES---LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKP 320
              + + A + +++     A ++A   + AQAQA  Q       +      A      + 
Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245

Query: 321 TFPAYTQSTASTTSTTNSTAAKPAASI-TSKPATLTTTSATSKLIHPDEDISLEERRAQL 379
              A  Q+ A   ST  +++  PA S  TS     +TTS T+      + +S    + Q 
Sbjct: 246 QVQAQVQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQT 305

Query: 380 PK---------YQRNLPRPGQAPIGNPPVGPIGGMMPPQP-GIPQQQGMRPPMPP--HGQ 427
           P             + P P   P+   P      + P  P  +PQ     P  PP     
Sbjct: 306 PSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPP 365

Query: 428 YGGHHQGMPGYLPGAMPPYGQGPPMVP 454
           +     GMP  LPG +P  G  PP+VP
Sbjct: 366 FRVPLPGMPIPLPGVLP--GMAPPIVP 390



 Score = 79.7 bits (195), Expect = 5e-15
 Identities = 95/374 (25%), Positives = 143/374 (38%), Gaps = 69/374 (18%)

Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMP-GVPPLMPGMPPVMP--GMPPGMMP----MGGMM 192
           PP+ +P  PP     G PP  PP  P G PP  P MPP+ P  G+PP M P        M
Sbjct: 44  PPLMRPP-PPFGMMRGPPP--PPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFM 100

Query: 193 PPGPGIPPLMPGM--PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPP--------APTAT 242
           PP     P  PGM  PPGMPP V  PG P +   + +    + N+ P        A T  
Sbjct: 101 PPPMSSMPPPPGMMFPPGMPP-VTAPGTPALPPTEEI---WVENKTPDGKVYYYNARTRE 156

Query: 243 VPAPQPPVTK--------PLFPSAGQMGTPVTSSSTASSNSESLS---ASSKALFPSTAQ 291
               +P   K        P+  +  Q+     + + A + +++ +   A ++A   + AQ
Sbjct: 157 SAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQ 216

Query: 292 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKP 351
           AQA  Q       +      A      +    A  Q+ A   ST  +++  PA S ++  
Sbjct: 217 AQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSS 276

Query: 352 AT-LTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP 410
           +T  +TTS T+      + +S    + Q P    ++  P            +    P   
Sbjct: 277 STPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATP-----------TVSVSTPAPT 325

Query: 411 GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM----- 465
             P Q   +P          H Q +P  +P ++P      P  PP    P R P+     
Sbjct: 326 ATPVQTVPQP----------HPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPI 375

Query: 466 -------GMRPPVM 472
                  GM PP++
Sbjct: 376 PLPGVLPGMAPPIV 389



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 42/122 (34%), Positives = 53/122 (43%), Gaps = 23/122 (18%)

Query: 361 SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV---GPIGGMM-----PPQP-- 410
           S+  +P E   L   + Q  +++   P P     G PP+    P  GMM     PP+P  
Sbjct: 11  SERFNPGE---LRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPPF 67

Query: 411 GIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 470
           G P      PPMPP G       G+P   P   PP+ Q PP +PP     P PP  M PP
Sbjct: 68  GRPPFDPNMPPMPPPG-------GIP---PPMGPPHLQRPPFMPPPMSSMPPPPGMMFPP 117

Query: 471 VM 472
            M
Sbjct: 118 GM 119



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 29/81 (35%), Positives = 40/81 (49%), Gaps = 10/81 (12%)

Query: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG 208
           P P    +PP +P  +P     +P  PPVM  +PP  +P+       PG+P  +PG+ PG
Sbjct: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPPFRVPL-------PGMPIPLPGVLPG 383

Query: 209 MPPPVPRPGIPPMTQAQAVSA 229
           M PP+  P I P     A  A
Sbjct: 384 MAPPIV-PMIHPQVAIAASPA 403



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 26/70 (37%), Positives = 36/70 (51%), Gaps = 9/70 (12%)

Query: 124 STSFQPQPVQPQQGYIPPMAQPGLP-PVPGAPGMPPG-IPPL---MPGVPPLMPGMPPVM 178
           +T  Q  P QP    +PP     +P P    P  PP  +PP    +PG+P  +PG   V+
Sbjct: 326 ATPVQTVP-QPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPG---VL 381

Query: 179 PGMPPGMMPM 188
           PGM P ++PM
Sbjct: 382 PGMAPPIVPM 391


>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
           [Homo sapiens]
          Length = 1125

 Score = 83.2 bits (204), Expect = 5e-16
 Identities = 104/388 (26%), Positives = 134/388 (34%), Gaps = 86/388 (22%)

Query: 107 KKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG 166
           KK +++  +    +++ +    P P +P    +PP+  P    VP     PP +PP  PG
Sbjct: 635 KKPENEVAQNGGAETSHTEPVSPIP-KPLPVPVPPIPVPAPITVP-----PPQVPPHQPG 688

Query: 167 VPPLMPGMPPVMPGM-PPGMMPMGGMMPP--GPGIPPLMPGMPPGMPPPVPRPGIPPMTQ 223
                   PPV+  + PP   P  G+ PP  GPG+P      PP  PPP  RPG  PM  
Sbjct: 689 --------PPVVGALQPPAFTPPLGIPPPGFGPGVP------PPPPPPPFLRPGFNPMH- 733

Query: 224 AQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSK 283
                 PG L   P P  T P   PP      P    +  P    S A  N+E  S  S 
Sbjct: 734 ----LPPGFLPPGPPPPITPPVSIPP------PHTPPISIP-NLVSGARGNAE--SGDSV 780

Query: 284 ALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP 343
            ++ S     A    P     +P+ S   T    P P       S       T    A+P
Sbjct: 781 KMYGSAVPPAAPTNLPTPPVTQPV-SLLGTQGVAPGPVIGLQAPS-------TGLLGARP 832

Query: 344 AASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIG 403
                 +P  +         + P                    P P       PP GP G
Sbjct: 833 GLIPLQRPPGMPPPHLQRFPLMPPR------------------PMPPHMMHRGPPPGPGG 874

Query: 404 GMMPPQPGIPQQQGMRPPMPPHGQY----GGHHQGMPGYLPGA-----------MPPYGQ 448
             MPP        GM+ P PPHG +    G    G PG  PG              P  Q
Sbjct: 875 FAMPP------PHGMKGPFPPHGPFVRPGGMPGLGGPGPGPGGPEDRDGRQQPPQQPQQQ 928

Query: 449 GPPMVP--PYQGGPPRPPMGMRPPVMSQ 474
             P  P  P Q    +PP   +PP   Q
Sbjct: 929 PQPQAPQQPQQQQQQQPPPSQQPPPTQQ 956



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 44/116 (37%), Positives = 49/116 (42%), Gaps = 11/116 (9%)

Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGG 190
           P+ P +   P M   G PP PG   MPP  P  M G  P  P  P V PG  PG+    G
Sbjct: 852 PLMPPRPMPPHMMHRGPPPGPGGFAMPP--PHGMKG--PFPPHGPFVRPGGMPGL----G 903

Query: 191 MMPPGPGIPPLMPG--MPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
              PGPG P    G   PP  P   P+P  P   Q Q    P    +PP PT   P
Sbjct: 904 GPGPGPGGPEDRDGRQQPPQQPQQQPQPQAPQQPQQQQQQQPPPSQQPP-PTQQQP 958



 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 89/364 (24%), Positives = 117/364 (32%), Gaps = 124/364 (34%)

Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           +  A TS   +PV P    IP      +PP+P  P  P  +PP  P VPP  PG P V  
Sbjct: 644 NGGAETS-HTEPVSP----IPKPLPVPVPPIP-VPA-PITVPP--PQVPPHQPGPPVVGA 694

Query: 180 GMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP 239
             PP   P                  P G+PPP   PG+PP                   
Sbjct: 695 LQPPAFTP------------------PLGIPPPGFGPGVPP------------------- 717

Query: 240 TATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP 299
               P P PP  +P F                               P          GP
Sbjct: 718 ----PPPPPPFLRPGFN------------------------------PMHLPPGFLPPGP 743

Query: 300 VGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN--STAAKPAA--SITSKPATLT 355
                 P++  P  T     P   +  +  A +  +     +A  PAA  ++ + P T  
Sbjct: 744 PPPITPPVSIPPPHTPPISIPNLVSGARGNAESGDSVKMYGSAVPPAAPTNLPTPPVTQP 803

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ----PG 411
            +   ++ + P   I L     Q P       RPG  P+  PP     GM PP     P 
Sbjct: 804 VSLLGTQGVAPGPVIGL-----QAPSTGLLGARPGLIPLQRPP-----GMPPPHLQRFPL 853

Query: 412 IPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 471
           +P +     PMPPH  + G             PP G G   +PP        P GM+ P 
Sbjct: 854 MPPR-----PMPPHMMHRG-------------PPPGPGGFAMPP--------PHGMKGPF 887

Query: 472 MSQG 475
              G
Sbjct: 888 PPHG 891



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 64/260 (24%), Positives = 93/260 (35%), Gaps = 55/260 (21%)

Query: 249 PVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLN 308
           PV + +  + G    PV  SS   + +   S  +    PS+    A  Q    T  + L 
Sbjct: 143 PVAENVTNNEGSPPPPVKVSSEPPTQATPNSVPAVPQLPSSDAFAAVAQLFQTTQGQQLQ 202

Query: 309 STPATTTEPPKPTFPAYTQS----TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLI 364
               T  +PPKP  PA   +      + T+   +T  +P+    + P     T+   KL+
Sbjct: 203 QILQTFQQPPKPQSPALDNAVMAQVQAITAQLKTTPTQPSEQKAAFPPPEQKTAFDKKLL 262

Query: 365 ----HPDEDISLEERR-------------AQLPKYQRNLPRPGQAPIG---NPPVGPIG- 403
               + DE  ++EE +             A +P           AP      PP  P G 
Sbjct: 263 DRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAASPPPPQAPFGF 322

Query: 404 -GMMPPQPGIPQQQGM-----------------RPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            G    QP   Q Q M                 + P+PP+GQ       MPG+     PP
Sbjct: 323 PGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQ-------MPGFGLLPTPP 375

Query: 446 YGQGPPMVPPYQGGPPRPPM 465
           +   PPM  P    PP PP+
Sbjct: 376 F---PPMAQPVI--PPTPPV 390



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 43/144 (29%), Positives = 56/144 (38%), Gaps = 27/144 (18%)

Query: 98  EQKTQESQKKKQQDDSDEYDD-------DDSAASTSFQPQPVQPQQ--GYIPPMAQPGL- 147
           EQKT   +K   + D D+  +       +D+ A T+  P    P      +P  A P   
Sbjct: 252 EQKTAFDKKLLDRFDYDDEPEAVEESKKEDTTAVTTTAPAAAVPPAPTATVPAAAAPAAA 311

Query: 148 -PPVPGAPGMPPGIPPLMPGVP---------PLMPG-----MPPVMPGMPPGMMPMGGMM 192
            PP P AP   PG     P            P M G     M   +P  P G MP  G++
Sbjct: 312 SPPPPQAPFGFPGDGMQQPAYTQHQNMDQFQPRMMGIQQDPMHHQVPLPPNGQMPGFGLL 371

Query: 193 PPGPGIPPLMPGMPPGMPPPVPRP 216
           P  P  P   P +PP   PPV +P
Sbjct: 372 PTPPFPPMAQPVIPP--TPPVQQP 393



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 1/43 (2%)

Query: 222 TQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTP 264
           T A   +AP     PPAPTATVPA   P      P     G P
Sbjct: 282 TTAVTTTAPAAAV-PPAPTATVPAAAAPAAASPPPPQAPFGFP 323


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 107/386 (27%), Positives = 124/386 (32%), Gaps = 103/386 (26%)

Query: 110 QDDSDEYDDDDSAASTSFQPQPVQPQ-----QGYIPPMAQPGLPPVPGAPGMPPGIPPLM 164
           Q+ +++   ++S +  +  PQ   PQ     QG  PP  +P  PP P     P G PP  
Sbjct: 17  QNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPP-PQGGNKPQGPPP-- 73

Query: 165 PGVPPLMPGM------PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPP--------GMP 210
           PG P   P        P   PG P G  P GG  P GP  PP  P  PP        G P
Sbjct: 74  PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPP 133

Query: 211 PPVPRPGIPPM--TQAQAVSAPGILNRPPAPTATVP-APQPPVTKPLF--PSAGQM---- 261
           PP    G PP         S PG    PP      P  P PP  KP    P  G+     
Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGP 193

Query: 262 ---GTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPP 318
              G P         +  S S   K   P   Q     QGP     KP    P    +P 
Sbjct: 194 PPPGKPQGPPPQGDKSRSSQSPPGKPQGP-PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252

Query: 319 KPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQ 378
            P  P   Q   +   + + +A  P                                + Q
Sbjct: 253 GPPPPGKPQGPPAQGGSKSQSARSPPG------------------------------KPQ 282

Query: 379 LPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGY 438
            P  Q           GN P GP     PP  G PQQ    P  PP GQ           
Sbjct: 283 GPPQQE----------GNNPQGP----PPPAGGNPQQ----PQAPPAGQ----------- 313

Query: 439 LPGAMPPYGQGPPMVPPYQGGPPRPP 464
                    QGPP  PP  G P RPP
Sbjct: 314 --------PQGPPR-PPQGGRPSRPP 330



 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 94/322 (29%), Positives = 103/322 (31%), Gaps = 51/322 (15%)

Query: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPP--------GMPPPVPRPGIPPM--TQA 224
           P ++ G P G  P GG  P GP  PP  P  PP        G PPP    G PP      
Sbjct: 29  PSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSR 88

Query: 225 QAVSAPGILNRPPAPTATVP-APQPPVTKPLFP---------SAGQMGTPVTSSSTASSN 274
              S PG    PP      P  P PP  KP  P              G P         +
Sbjct: 89  SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKS 148

Query: 275 SESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTS 334
               S   K   P   Q     QGP     KP    P    +P  P  P   Q       
Sbjct: 149 RSPRSPPGKPQGP-PPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGD 207

Query: 335 TTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPI 394
            + S+ + P      KP              P              K Q   P+ G  P 
Sbjct: 208 KSRSSQSPP-----GKPQGPPPQGGNQPQGPPPPP----------GKPQGPPPQGGNKPQ 252

Query: 395 GNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHG---QYGGHHQGMPGYLPGAMPPYGQGP- 450
           G PP G   G  P Q G   Q    PP  P G   Q G + QG P       PP G  P 
Sbjct: 253 GPPPPGKPQG-PPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPP-------PPAGGNPQ 304

Query: 451 -PMVPP--YQGGPPRPPMGMRP 469
            P  PP     GPPRPP G RP
Sbjct: 305 QPQAPPAGQPQGPPRPPQGGRP 326



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 48/134 (35%), Positives = 51/134 (38%), Gaps = 14/134 (10%)

Query: 108 KQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGV 167
           K Q    + D   S+ S   +PQ   PQ G  P     G PP PG P  PP      P  
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ----GPPPPPGKPQGPPPQGGNKPQG 253

Query: 168 PPLMPGMPPVMPGMPP---GMMPMGGMMPPG-PGIPPLMPGMPPGMPPPVPRPGIPPMTQ 223
           PP     PP  P  PP   G        PPG P  PP   G  P  PPP P  G P   Q
Sbjct: 254 PP-----PPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPP-PAGGNPQQPQ 307

Query: 224 AQAVSAPGILNRPP 237
           A     P    RPP
Sbjct: 308 APPAGQPQGPPRPP 321



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 43/124 (34%), Positives = 49/124 (39%), Gaps = 15/124 (12%)

Query: 359 ATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ---- 414
           A S   + +ED+S EE     P      P+      GN P GP     PP PG PQ    
Sbjct: 12  ALSSAQNLNEDVSQEES----PSLIAGNPQGPSPQGGNKPQGP-----PPPPGKPQGPPP 62

Query: 415 QQGMRP--PMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVM 472
           Q G +P  P PP    G   QG     P + P   QGPP     Q   P PP G      
Sbjct: 63  QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 122

Query: 473 SQGG 476
            QGG
Sbjct: 123 PQGG 126



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 37/108 (34%), Positives = 44/108 (40%), Gaps = 11/108 (10%)

Query: 376 RAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQ----QQGMRP--PMPPHGQYG 429
           +++ P+     P+      GN P GP     PP PG PQ    Q G RP  P PP    G
Sbjct: 86  KSRSPRSPPGKPQGPPPQGGNQPQGP-----PPPPGKPQGPPPQGGNRPQGPPPPGKPQG 140

Query: 430 GHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGGR 477
              QG     P + P   QGPP     Q   P PP G       QGG+
Sbjct: 141 PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 107/426 (25%), Positives = 148/426 (34%), Gaps = 107/426 (25%)

Query: 117 DDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG-------VPP 169
           D        SF+P P     GY  PM  P        PG PP  P L PG        PP
Sbjct: 173 DSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232

Query: 170 LMP-----------------GMPPVMP---------GMPPGMMPM----GGMMPPGPGIP 199
           + P                   PP  P         G PP   P     GG +P  P  P
Sbjct: 233 MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP-P 291

Query: 200 PLMPGMPPGMPPP------------------------VPRP--------GIPPMTQAQAV 227
              P + P +PPP                        +P P        G+PP  +    
Sbjct: 292 ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351

Query: 228 SAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFP 287
            AP   + PPA ++   AP PP+  P   S        +SSS A+S+S S S+SS + FP
Sbjct: 352 LAPSPHSLPPASSS---APAPPMRFPYSSS--------SSSSAAASSSSSSSSSSASPFP 400

Query: 288 STAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAKPAAS 346
           +   +QA    P    F P  S  + + +PPK T P+  +Q+  S          +  A+
Sbjct: 401 A---SQALPSYP--HSFPPPTSL-SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454

Query: 347 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
             + P     ++      HP         + Q  + Q+   +  Q    +   GP     
Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP----- 509

Query: 407 PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP-------YQGG 459
           PP    P       P+     +  H   M   L G++ PY  GP  +PP        Q G
Sbjct: 510 PPPGAFPH------PLEGGSSHHAHPYAMSPSL-GSLRPYPPGPAHLPPPHSQVSYSQAG 562

Query: 460 PPRPPM 465
           P  PP+
Sbjct: 563 PNGPPV 568



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 100/415 (24%), Positives = 141/415 (33%), Gaps = 55/415 (13%)

Query: 83  EGIPEKDMDERRRLLEQKT-QESQKKKQQDDSDEYDDDDSAASTSFQPQPV-QPQQGYIP 140
           E I E + +E     + KT QE  + +   D D  D        S  P+ + Q  +   P
Sbjct: 74  EEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP 133

Query: 141 PMAQPG-----------LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMG 189
            +  PG           L   P  P  PP + P  P  P   P  P       P + P G
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTG 193

Query: 190 GMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP--- 246
              P  P    +    PPG PP  P P + P      +S P +  +     ++V  P   
Sbjct: 194 YHAPMEPPTSRMFQA-PPGAPP--PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG 250

Query: 247 --QPPVTKPL-FPSAGQMGTPVTSSSTASSNSESL-SASSKALF----------PSTAQA 292
              PP T P+   S+G  G P T   T      +L SA   A F          P+    
Sbjct: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310

Query: 293 QAAVQGPVGTDFKPLNS---TPATTTE-----PPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             A   P G   +PL     +P    +     PP P        +  +    +S+A  P 
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 404
                  ++ ++ +A+S         S       LP Y  + P P    + N P      
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP------ 424

Query: 405 MMPPQPGIPQQ----QGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
               QP +P Q    QG  PP PP+G+   +    PG  P   P  G      PP
Sbjct: 425 PKYTQPSLPSQAVWSQG-PPPPPPYGRLLANSNAHPGPFP---PSTGAQSTAHPP 475



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 100/427 (23%), Positives = 140/427 (32%), Gaps = 103/427 (24%)

Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPP------VMPGMPP--GMMPMGGM 191
           PP   P      GA G PP  PP  P     +P  PP      V P +PP   + P+   
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA 313

Query: 192 M--PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPP 249
              PPG G  PL   +P          G+PP  +     AP   + PPA ++   AP PP
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS---APAPP 370

Query: 250 VTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKAL------FPSTAQAQAAVQGPVGTD 303
           +  P + S+       +SSS++SS+S S   +S+AL      FP       + Q P  T 
Sbjct: 371 MRFP-YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429

Query: 304 FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 363
              L S    +  PP P  P Y +  A++ +          A  T+ P       +T   
Sbjct: 430 -PSLPSQAVWSQGPPPP--PPYGRLLANSNAHPGPFPPSTGAQSTAHPPV-----STHHH 481

Query: 364 IHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPP---------------VGPIGGMMPP 408
            H  +    ++++ Q  + Q++    G  P G  P               + P  G + P
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541

Query: 409 QPGIPQQ-------------------------------QGMRP---PMPPHGQYGGHHQG 434
            P  P                                 QG  P   P P  G  G  +  
Sbjct: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601

Query: 435 MP-----------------------GYL---PGAMPPYGQGPPMVPPYQGGPPRPPMGMR 468
            P                       GY    P   PPYG+  P    Y+   P       
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 469 PPVMSQG 475
           PP    G
Sbjct: 662 PPSFRTG 668



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 70/260 (26%), Positives = 91/260 (35%), Gaps = 52/260 (20%)

Query: 206 PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPV 265
           PPG  P     G        A+S P + +  P P      P PP ++  +  AG  G PV
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMS-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPV 568

Query: 266 TSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY 325
           +SSS +SS++   S       PS        QGP G  +             P P  P  
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPS--------QGPQGAPY-------------PFPPVPTV 607

Query: 326 TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
           T S+A+ ++   + A+ PA   T+ P                            P Y + 
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASP-------------------------PGPPPYGKR 642

Query: 386 LPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            P PG      PP    G   PP        G R   PP G  G    G P   PG +PP
Sbjct: 643 APSPGAYKTATPPGYKPGS--PPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPLPP 699

Query: 446 YG-QGPPMVPPYQGGPPRPP 464
            G  G P +PP    P   P
Sbjct: 700 AGPSGLPSLPPPPAAPASGP 719



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 84/349 (24%), Positives = 124/349 (35%), Gaps = 30/349 (8%)

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLP-PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           S+ S+S   Q   P     P     G P P P  P +      L   +  +         
Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKT 630

Query: 180 GMPPGMMPMGGMMP-PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPA 238
             PPG  P G   P PG       PG  PG PP   R G PP  +  +  A     +P +
Sbjct: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF-RTGTPPGYRGTSPPAGPGTFKPGS 689

Query: 239 PTATVPAPQPPV------TKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQA 292
           PT   P P PP       + P  P+A   G P++++      +E        + P    A
Sbjct: 690 PTVG-PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP----A 744

Query: 293 QAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPA 352
           ++    P   D     S  A   +     F +  +S         S  AK  A +  K  
Sbjct: 745 RSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVR 804

Query: 353 TLTTTSATS-KLIHPDEDISLEERRAQLPKYQRN--LPRPGQAPIGNPPVGPIGGMMPPQ 409
                 A   K    + +   E  R +  + +R+  L + G+AP+  P +GP+    P +
Sbjct: 805 REAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFE 864

Query: 410 PG-----IPQQQGM-RPPMPPHGQYGGHHQGMPG------YLP-GAMPP 445
           PG     +P   G   P +    +Y   H   PG      Y+P GA+ P
Sbjct: 865 PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDP 913



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 48/218 (22%), Positives = 78/218 (35%), Gaps = 75/218 (34%)

Query: 90   MDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPP 149
            +++ RR  EQ+ +E ++++++ + ++  + +         + V+  Q    P+  P L P
Sbjct: 800  VEKVRREAEQRAREEKEREREREREKEREREKERELE---RSVKLAQEGRAPVECPSLGP 856

Query: 150  VPGAPGMPPG-----IPPLM-PGVPPLMP----GMPPVM-PGMP--PGMMPMGGMMP--- 193
            VP  P   PG     +PP + P  P L        P VM PG    P  +P+G + P   
Sbjct: 857  VPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLL 916

Query: 194  -----------------------------------------------PGPGIPP------ 200
                                                           PGPG+ P      
Sbjct: 917  GYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976

Query: 201  --LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
              L PG PPG+ P    P + P+ + +   A G   RP
Sbjct: 977  LALQPG-PPGLHPFPFHPSLGPLERERLALAAGPALRP 1013


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 107/426 (25%), Positives = 148/426 (34%), Gaps = 107/426 (25%)

Query: 117 DDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG-------VPP 169
           D        SF+P P     GY  PM  P        PG PP  P L PG        PP
Sbjct: 173 DSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPP 232

Query: 170 LMP-----------------GMPPVMP---------GMPPGMMPM----GGMMPPGPGIP 199
           + P                   PP  P         G PP   P     GG +P  P  P
Sbjct: 233 MGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP-P 291

Query: 200 PLMPGMPPGMPPP------------------------VPRP--------GIPPMTQAQAV 227
              P + P +PPP                        +P P        G+PP  +    
Sbjct: 292 ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351

Query: 228 SAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFP 287
            AP   + PPA ++   AP PP+  P   S        +SSS A+S+S S S+SS + FP
Sbjct: 352 LAPSPHSLPPASSS---APAPPMRFPYSSS--------SSSSAAASSSSSSSSSSASPFP 400

Query: 288 STAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAKPAAS 346
           +   +QA    P    F P  S  + + +PPK T P+  +Q+  S          +  A+
Sbjct: 401 A---SQALPSYP--HSFPPPTSL-SVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLAN 454

Query: 347 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
             + P     ++      HP         + Q  + Q+   +  Q    +   GP     
Sbjct: 455 SNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGP----- 509

Query: 407 PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP-------YQGG 459
           PP    P       P+     +  H   M   L G++ PY  GP  +PP        Q G
Sbjct: 510 PPPGAFPH------PLEGGSSHHAHPYAMSPSL-GSLRPYPPGPAHLPPPHSQVSYSQAG 562

Query: 460 PPRPPM 465
           P  PP+
Sbjct: 563 PNGPPV 568



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 100/415 (24%), Positives = 141/415 (33%), Gaps = 55/415 (13%)

Query: 83  EGIPEKDMDERRRLLEQKT-QESQKKKQQDDSDEYDDDDSAASTSFQPQPV-QPQQGYIP 140
           E I E + +E     + KT QE  + +   D D  D        S  P+ + Q  +   P
Sbjct: 74  EEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSP 133

Query: 141 PMAQPG-----------LPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMG 189
            +  PG           L   P  P  PP + P  P  P   P  P       P + P G
Sbjct: 134 SIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTG 193

Query: 190 GMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP--- 246
              P  P    +    PPG PP  P P + P      +S P +  +     ++V  P   
Sbjct: 194 YHAPMEPPTSRMFQA-PPGAPP--PHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGG 250

Query: 247 --QPPVTKPL-FPSAGQMGTPVTSSSTASSNSESL-SASSKALF----------PSTAQA 292
              PP T P+   S+G  G P T   T      +L SA   A F          P+    
Sbjct: 251 KQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPL 310

Query: 293 QAAVQGPVGTDFKPLNS---TPATTTE-----PPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             A   P G   +PL     +P    +     PP P        +  +    +S+A  P 
Sbjct: 311 NNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGG 404
                  ++ ++ +A+S         S       LP Y  + P P    + N P      
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP------ 424

Query: 405 MMPPQPGIPQQ----QGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
               QP +P Q    QG  PP PP+G+   +    PG  P   P  G      PP
Sbjct: 425 PKYTQPSLPSQAVWSQG-PPPPPPYGRLLANSNAHPGPFP---PSTGAQSTAHPP 475



 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 100/427 (23%), Positives = 140/427 (32%), Gaps = 103/427 (24%)

Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPP------VMPGMPP--GMMPMGGM 191
           PP   P      GA G PP  PP  P     +P  PP      V P +PP   + P+   
Sbjct: 254 PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNA 313

Query: 192 M--PPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPP 249
              PPG G  PL   +P          G+PP  +     AP   + PPA ++   AP PP
Sbjct: 314 SASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSS---APAPP 370

Query: 250 VTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKAL------FPSTAQAQAAVQGPVGTD 303
           +  P + S+       +SSS++SS+S S   +S+AL      FP       + Q P  T 
Sbjct: 371 MRFP-YSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQ 429

Query: 304 FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 363
              L S    +  PP P  P Y +  A++ +          A  T+ P       +T   
Sbjct: 430 -PSLPSQAVWSQGPPPP--PPYGRLLANSNAHPGPFPPSTGAQSTAHPPV-----STHHH 481

Query: 364 IHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPP---------------VGPIGGMMPP 408
            H  +    ++++ Q  + Q++    G  P G  P               + P  G + P
Sbjct: 482 HHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRP 541

Query: 409 QPGIPQQ-------------------------------QGMRP---PMPPHGQYGGHHQG 434
            P  P                                 QG  P   P P  G  G  +  
Sbjct: 542 YPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601

Query: 435 MP-----------------------GYL---PGAMPPYGQGPPMVPPYQGGPPRPPMGMR 468
            P                       GY    P   PPYG+  P    Y+   P       
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 469 PPVMSQG 475
           PP    G
Sbjct: 662 PPSFRTG 668



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 70/260 (26%), Positives = 91/260 (35%), Gaps = 52/260 (20%)

Query: 206 PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPV 265
           PPG  P     G        A+S P + +  P P      P PP ++  +  AG  G PV
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMS-PSLGSLRPYPPGPAHLP-PPHSQVSYSQAGPNGPPV 568

Query: 266 TSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY 325
           +SSS +SS++   S       PS        QGP G  +             P P  P  
Sbjct: 569 SSSSNSSSSTSQGSYPCSHPSPS--------QGPQGAPY-------------PFPPVPTV 607

Query: 326 TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
           T S+A+ ++   + A+ PA   T+ P                            P Y + 
Sbjct: 608 TTSSATLSTVIATVASSPAGYKTASP-------------------------PGPPPYGKR 642

Query: 386 LPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            P PG      PP    G   PP        G R   PP G  G    G P   PG +PP
Sbjct: 643 APSPGAYKTATPPGYKPGS--PPSFRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPLPP 699

Query: 446 YG-QGPPMVPPYQGGPPRPP 464
            G  G P +PP    P   P
Sbjct: 700 AGPSGLPSLPPPPAAPASGP 719



 Score = 57.0 bits (136), Expect = 4e-08
 Identities = 84/349 (24%), Positives = 124/349 (35%), Gaps = 30/349 (8%)

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLP-PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           S+ S+S   Q   P     P     G P P P  P +      L   +  +         
Sbjct: 571 SSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKT 630

Query: 180 GMPPGMMPMGGMMP-PGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPA 238
             PPG  P G   P PG       PG  PG PP   R G PP  +  +  A     +P +
Sbjct: 631 ASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSF-RTGTPPGYRGTSPPAGPGTFKPGS 689

Query: 239 PTATVPAPQPPV------TKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQA 292
           PT   P P PP       + P  P+A   G P++++      +E        + P    A
Sbjct: 690 PTVG-PGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP----A 744

Query: 293 QAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPA 352
           ++    P   D     S  A   +     F +  +S         S  AK  A +  K  
Sbjct: 745 RSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVR 804

Query: 353 TLTTTSATS-KLIHPDEDISLEERRAQLPKYQRN--LPRPGQAPIGNPPVGPIGGMMPPQ 409
                 A   K    + +   E  R +  + +R+  L + G+AP+  P +GP+    P +
Sbjct: 805 REAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFE 864

Query: 410 PG-----IPQQQGM-RPPMPPHGQYGGHHQGMPG------YLP-GAMPP 445
           PG     +P   G   P +    +Y   H   PG      Y+P GA+ P
Sbjct: 865 PGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDP 913



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 48/218 (22%), Positives = 78/218 (35%), Gaps = 75/218 (34%)

Query: 90   MDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPP 149
            +++ RR  EQ+ +E ++++++ + ++  + +         + V+  Q    P+  P L P
Sbjct: 800  VEKVRREAEQRAREEKEREREREREKEREREKERELE---RSVKLAQEGRAPVECPSLGP 856

Query: 150  VPGAPGMPPG-----IPPLM-PGVPPLMP----GMPPVM-PGMP--PGMMPMGGMMP--- 193
            VP  P   PG     +PP + P  P L        P VM PG    P  +P+G + P   
Sbjct: 857  VPHRPPFEPGSAVATVPPYLGPDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLL 916

Query: 194  -----------------------------------------------PGPGIPP------ 200
                                                           PGPG+ P      
Sbjct: 917  GYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGG 976

Query: 201  --LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
              L PG PPG+ P    P + P+ + +   A G   RP
Sbjct: 977  LALQPG-PPGLHPFPFHPSLGPLERERLALAAGPALRP 1013


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 79.0 bits (193), Expect = 9e-15
 Identities = 82/309 (26%), Positives = 104/309 (33%), Gaps = 33/309 (10%)

Query: 131  PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPG-----MPPVMPGMPPGM 185
            P  P     PP   P  PP       PP   P  P   P+ P      +PP     PP  
Sbjct: 1470 PSPPTTTPSPPTTTPS-PPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTT 1528

Query: 186  M---PMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
                P     P  P   P+ P       PP   P  PP T     + P     P  PT T
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT----TTTPPPTTTPSPPTTT 1584

Query: 243  VPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGT 302
             P+P P +T    P       P T+++T    +   + S     P T         P  T
Sbjct: 1585 TPSP-PTITTTTPPPTTTPSPPTTTTTTPPPTT---TPSPPTTTPITPPTSTTTLPPTTT 1640

Query: 303  DFKPLNSTPATTTEPPKPTFPA----YTQSTASTTSTTNSTAAKPAASITSKPATLTTTS 358
               P    P TTT PP  T P+     T S   TT+TT      P++ IT+ P+  TTT 
Sbjct: 1641 PSPP----PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM 1696

Query: 359  AT-SKLIHPDEDISLEERRAQL-----PKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGI 412
             T S    P   I+     +       P      P P   P  +PP   +  + P     
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTP--SPPTTTMTTLPPTTTSS 1754

Query: 413  PQQQGMRPP 421
            P      PP
Sbjct: 1755 PLTTTPLPP 1763



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 74/291 (25%), Positives = 96/291 (32%), Gaps = 29/291 (9%)

Query: 140  PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIP 199
            PP   P  PP      +PP   P  P      P  PP     PP    +     P P   
Sbjct: 1401 PPTTTPSPPPT-STTTLPPTTTPSPPTTTTTTP--PPTTTPSPP----ITTTTTPPPTTT 1453

Query: 200  PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPG---ILNRPPAPTATVPAPQPPVTKPLFP 256
            P  P      PPP   P  P  T +   + P         P PT T   P PP T P+ P
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITP 1510

Query: 257  SAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPA---T 313
             A     P T++ +  + + +    +    P T      +  P  T   P  +TP+   T
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTT---TPITPPTSTTTLPPTTTPSPPPT 1567

Query: 314  TTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLE 373
            TT  P PT      +T + +  T +T   P  +  S P T TTT   +    P     + 
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627

Query: 374  ERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP 424
                  P     LP     P   P   P     PP    P       P PP
Sbjct: 1628 P-----PTSTTTLP-----PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1668



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 65/237 (27%), Positives = 83/237 (35%), Gaps = 19/237 (8%)

Query: 140  PPMAQPGLPPVPGA---PGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGP 196
            PP   P  PP       P   P  PP     PP  P   P  P       P      P P
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP--PTTTPSPPTTTTPSPPTITTTTPPP 1598

Query: 197  GIPPLMPGMPPGMPPPVPRPGIP---PMTQAQAVSA--PGILNRPPAPTATVPAPQPPVT 251
               P  P      PPP   P  P   P+T   + +   P     PP  T T P   PP T
Sbjct: 1599 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP---PPTT 1655

Query: 252  KPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNST- 310
             P  P+      P+T+++T    +   S  +    PS          P  T   P+ +T 
Sbjct: 1656 TPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT--PSPPTTTMTTPSPTTTPSSPITTTT 1713

Query: 311  -PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHP 366
             P++TT P  P     T S  +T S   +T      + TS P  LTTT     +  P
Sbjct: 1714 TPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP--LTTTPLPPSITPP 1768



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 64/247 (25%), Positives = 83/247 (33%), Gaps = 28/247 (11%)

Query: 124  STSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPP 183
            ST+  P    P     PP      PP    P  P    P  P +    P  PP     PP
Sbjct: 1552 STTTLPPTTTPS----PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP--PPTTTPSPP 1605

Query: 184  GMM---PMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
                  P     P  P   P+ P       PP   P  PP T     + P     P  PT
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT----TTTPPPTTTPSPPT 1661

Query: 241  ATVPAPQ-------PPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQ 293
             T P+P        PP T P  P       P T+ +T S  +      S  +  +T  + 
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT----TPSSPITTTTTPSS 1717

Query: 294  AAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPAT 353
                 P  T      +TP+ TT P  PT    T    +T+S   +T   P+ +  +    
Sbjct: 1718 TTTPSPPPTTM----TTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPF 1773

Query: 354  LTTTSAT 360
             TTT  T
Sbjct: 1774 STTTPTT 1780



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 65/254 (25%), Positives = 83/254 (32%), Gaps = 48/254 (18%)

Query: 196  PGIPPLMPGMPP-------------------GMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
            P  P   P  PP                     PPP   P  PP+T       P     P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPS-PPIT-TTTTPPPTTTPSP 1456

Query: 237  PAPTATVP----APQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQA 292
            P  T T P     P PP T P  P+     TP   ++T ++   + + S     P T  A
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTT----TPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512

Query: 293  QAAVQGPVGTDFKP--LNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSK 350
                  P  T   P    +TP  TT P  PT    T  T++TT    +T + P  + T+ 
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572

Query: 351  PATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQP 410
            P T T +  T+    P             P      P P   P  +PP        PP  
Sbjct: 1573 PPTTTPSPPTTTTPSP-------------PTITTTTPPPTTTP--SPPTTTT--TTPPPT 1615

Query: 411  GIPQQQGMRPPMPP 424
              P      P  PP
Sbjct: 1616 TTPSPPTTTPITPP 1629



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 56/213 (26%), Positives = 73/213 (34%), Gaps = 24/213 (11%)

Query: 125  TSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPG-----MPPVMP 179
            T+  P P        PP   P  PP       PP   P  P   P+ P      +PP   
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPS-PPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640

Query: 180  GMPPGMMPMGGMMPPG---PGIPPLMPGMPP----GMPPPVPRPGIPPMTQAQAVSAPGI 232
              PP   P     PP    P  P      PP      PPP   P  P  T     S P  
Sbjct: 1641 PSPP---PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP---SPPTT 1694

Query: 233  LNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKAL--FPSTA 290
                P+PT T   P  P+T    PS+    +P  ++ T  S + + S  +  +   P T 
Sbjct: 1695 TMTTPSPTTT---PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTT 1751

Query: 291  QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFP 323
             +      P+     P   +P +TT P  P  P
Sbjct: 1752 TSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 53/219 (24%), Positives = 75/219 (34%), Gaps = 34/219 (15%)

Query: 220  PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSS----TASSNS 275
            PM +     +P      P PT+T   P  P T P  P+      P T++     T ++  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLP--PTTTPSPPTTTTTTPPPTTTPSPPITTTTTP 1448

Query: 276  ESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPA----TTTEPPKPTFPA------Y 325
               +  S  +  +T         P  T   P  +TP+    TTT PP  T P+       
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508

Query: 326  TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
            T   ++TT    +T + P  + T+ P T T +  T+  I P             P     
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-------------PTSTTT 1555

Query: 386  LPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP 424
            LP     P   P   P     PP    P       P PP
Sbjct: 1556 LP-----PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP 1589



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 55/188 (29%), Positives = 72/188 (38%), Gaps = 17/188 (9%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAP----GILNRPPA 238
            P   P G   P    I       P   P     P   P+T    V+      G    PP 
Sbjct: 4140 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT 4199

Query: 239  PTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSES---LSASSKAL-FPSTAQAQA 294
             T+T P  +   + P      +  TP TS ST+S  +ES   LS    A+   STA    
Sbjct: 4200 HTSTAPIAELTTSNP----PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255

Query: 295  AVQGPVGTDFKPLNSTPATTTEPP-KPTFPAYTQS----TASTTSTTNSTAAKPAASITS 349
                   +    L+  P+TTT PP  PT    T S    T ST  TT ++A  P  +  S
Sbjct: 4256 PTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315

Query: 350  KPATLTTT 357
             P+ + TT
Sbjct: 4316 TPSIIRTT 4323



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 54/225 (24%), Positives = 71/225 (31%), Gaps = 7/225 (3%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968

Query: 243  VPAPQPPVTKPLFPSAGQ--MGTPVTSSSTASSNSESLSASSKALFP-STAQAQAAVQGP 299
                   VT    P+  Q    TP+T+++T +         +    P +T         P
Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2028

Query: 300  VGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSA 359
             GT          TTT  P PT P  TQ T +TT  T +T   P  + T      TT   
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPT-PTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2086

Query: 360  TSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            T+  + P    +  +     P        P   P G   P   PI
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2131



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 1932 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1991

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 1992 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2050

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2037

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2038 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2096

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2024 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2083

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2142

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2246



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2070 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2130 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2188

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2116 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2176 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2234

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2280

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2268 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2326

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2386

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2387 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2314 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2372

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2433 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2360 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2418

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2405

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2406 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2464

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2510

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2497

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2556

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2544 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2602

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2590 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2648

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2709 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2635

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2694

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2681

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2682 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2740

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2728 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2786

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2832

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2819

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2820 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2878

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2924

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 2985 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2911

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 2970

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2957

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 2958 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3016

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3004 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3062

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3049

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3050 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3108

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3095

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3096 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3154

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3142 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3200

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3187

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3188 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3246

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3233

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3234 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3292

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3338

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3325

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3326 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3384

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3430

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3418 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3476

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3463

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3464 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3522

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3509

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3510 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3568

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3556 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3614

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3601

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3602 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3660

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3647

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3648 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3706

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3694 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3752

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3798

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3844

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3832 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3890

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3877

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3878 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3936

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 3997 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3864 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3923

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3924 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 3982

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4042

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 4043 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4086



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 51/224 (22%), Positives = 69/224 (30%), Gaps = 5/224 (2%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3910 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3969

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPV 300
                   VT    P+  Q  T  P+T+++T +         +    P T         P 
Sbjct: 3970 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-TVTPTPT 4028

Query: 301  GTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
             T  +   +TP TTT    PT       T +TT  T +T   P  + T      TT   T
Sbjct: 4029 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088

Query: 361  SKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
            +  + P    +  +     P        P   P G   P   PI
Sbjct: 4089 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 46/188 (24%), Positives = 67/188 (35%), Gaps = 14/188 (7%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 4117 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4176

Query: 243  VPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGT 302
                   VT    P+  Q G P   + T+++    L+ S+     ST Q   +   P+  
Sbjct: 4177 PITTTTTVTPTPTPTGTQTGPP---THTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233

Query: 303  DFKPLNSTPA----TTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTS 358
                L++ P     T+T PP       +  TA TT++   T + P ++ TS P T T  +
Sbjct: 4234 STTLLSTLPPAIEMTSTAPP-------STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGT 4286

Query: 359  ATSKLIHP 366
             T     P
Sbjct: 4287 TTGSSSAP 4294



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 45/178 (25%), Positives = 61/178 (34%), Gaps = 17/178 (9%)

Query: 240  TATVPAPQPPVTKPL------FPSAGQMG------TPVTSSSTASSNSESLSASSKALFP 287
            T T   P PP T P+       P+    G      TP+T+++T +         +    P
Sbjct: 1887 TTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1946

Query: 288  -STAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
             +T         P GT          TTT  P PT P  TQ T +TT  T +T   P  +
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQ-TPTTTPITTTTTVTPTPT 2004

Query: 347  ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG--NPPVGPI 402
             T      TT   T+  + P    +  +     P        P   P G   P   PI
Sbjct: 2005 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2062



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 47/220 (21%), Positives = 70/220 (31%), Gaps = 12/220 (5%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 4048 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT----------PTPT 4097

Query: 243  VPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGT 302
                Q P T P+  +     TP  + +   + +   + ++    P+    Q     P+ T
Sbjct: 4098 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-T 4156

Query: 303  DFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKP-ATLTTTSATS 361
                +  TP  T      T P  T +T + T T   T   P    ++ P A LTT++   
Sbjct: 4157 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPP 4216

Query: 362  KLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGP 401
            +   P    S      +       LP   +     PP  P
Sbjct: 4217 ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP 4256



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 57/250 (22%), Positives = 76/250 (30%), Gaps = 12/250 (4%)

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTAT 242
            P   P G   P    I       P   P     P   P+T    V+          PT T
Sbjct: 3956 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4015

Query: 243  VPAPQPPVTKPLFPSAGQMGT--PVTSSSTASSNSESLSASSKALFP-STAQAQAAVQGP 299
                   VT    P+  Q  T  P+T+++T +         +    P +T         P
Sbjct: 4016 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4075

Query: 300  VGTDFKPLNSTPATTTEPPKPTFPAYTQSTAS----TTSTTNSTAAKPAASITSKPATLT 355
             GT          TTT  P PT P  TQ+  +    TT+T   T   P  + T  P T  
Sbjct: 4076 TGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPT---PTPTGTQTPTTTP 4131

Query: 356  TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQ 415
             T+ T+    P    +       +       P P       P   PI       P  P  
Sbjct: 4132 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-TPTP 4190

Query: 416  QGMRPPMPPH 425
             G +   P H
Sbjct: 4191 TGTQTGPPTH 4200



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 11/127 (8%)

Query: 237  PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFP-STAQAQAA 295
            P  T T   P P  T    P+     TP+T+++T +         +    P +T      
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955

Query: 296  VQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTAS----TTSTTNSTAAKPAASI-TSK 350
               P GT          TTT  P PT P  TQ+  +    TT+T   T         T+ 
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPT-PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2014

Query: 351  PATLTTT 357
            P T TTT
Sbjct: 2015 PITTTTT 2021



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 18/51 (35%), Positives = 21/51 (41%)

Query: 310  TPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSAT 360
            T  TTT    PT P  T  T +TT T   T        T+   T TT + T
Sbjct: 1883 TTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 1933



 Score = 29.6 bits (65), Expect = 6.3
 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 4/53 (7%)

Query: 305  KPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTT 357
            +P   T  TT  P  PT    T +T  T + T +    P    T+ P T TTT
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 1929


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 90/310 (29%), Positives = 111/310 (35%), Gaps = 70/310 (22%)

Query: 141 PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPP 200
           P A P LP  P     PP  PPLM G+PP  P +P  +P  PPG +P+  M P GP   P
Sbjct: 217 PPAPPSLPAGPPGVKRPP--PPLMNGLPP-RPPLPESLPPPPPGGLPLPPMPPTGPA--P 271

Query: 201 LMPGMPPGMPPPV-----PRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP-QPPVTKPL 254
             P  PP +PPP      P P + P        APG+   PPAP    PAP   P T  +
Sbjct: 272 SGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGV--HPPAPGVHPPAPGVHPPTSGV 329

Query: 255 FPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATT 314
            P A  +  P                      P        V  P      P    PA  
Sbjct: 330 HPPAPGVHPPA---------------------PGVHPPAPGVHPPA-----PGVHPPAPG 363

Query: 315 TEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEE 374
             PP P+   + Q+     +   + A  P A     PA      A    +HP        
Sbjct: 364 VHPP-PSAGVHPQAPGVHPA---APAVHPQAPGVHPPAPGMHPQAPG--VHP-------- 409

Query: 375 RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG 434
              Q P    + P     P G  P  P  G+ PP P  P    +RPP+P  G        
Sbjct: 410 ---QPPGVHPSAPGVHPQPPGVHPSNP--GVHPPTPMPPM---LRPPLPSEG-------- 453

Query: 435 MPGYLPGAMP 444
            PG +P   P
Sbjct: 454 -PGNIPPPPP 462



 Score = 78.2 bits (191), Expect = 2e-14
 Identities = 52/141 (36%), Positives = 65/141 (46%), Gaps = 18/141 (12%)

Query: 129 PQPVQPQQGYIPPMAQPGLP--------PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           P+P  P+   +PP    GLP        P P  P  PP +PP  PGV P  P + P   G
Sbjct: 243 PRPPLPES--LPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASG 300

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGM-PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAP 239
           + P   P  G+ PP PG+ P  PG+ PP      P PG+ P        APG+   PPAP
Sbjct: 301 VHP---PAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGV--HPPAP 355

Query: 240 TATVPAP--QPPVTKPLFPSA 258
               PAP   PP +  + P A
Sbjct: 356 GVHPPAPGVHPPPSAGVHPQA 376



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 55/179 (30%), Positives = 68/179 (37%), Gaps = 46/179 (25%)

Query: 129 PQP-VQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMP 187
           P P V P    + P A    PP PG     PG+ P  PGV P   G+ P  PG+ P   P
Sbjct: 283 PAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHP---P 339

Query: 188 MGGMMPPGPGIPPLMPGM--------------------------------PPGMPPPVP- 214
             G+ PP PG+ P  PG+                                 PG+ PP P 
Sbjct: 340 APGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPG 399

Query: 215 ----RPGIPPMTQAQAVSAPGILNRPPA-----PTATVPAPQPPVTKPLFPSAGQMGTP 264
                PG+ P       SAPG+  +PP      P    P P PP+ +P  PS G    P
Sbjct: 400 MHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIP 458



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 94/316 (29%), Positives = 107/316 (33%), Gaps = 94/316 (29%)

Query: 175 PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234
           PP  P +P G  P G   PP    PPLM G+PP   PP+P    PP         PG L 
Sbjct: 217 PPAPPSLPAG--PPGVKRPP----PPLMNGLPPR--PPLPESLPPP--------PPGGLP 260

Query: 235 RPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA 294
            PP P  T PAP  P   P  P       P                             A
Sbjct: 261 LPPMPP-TGPAPSGPPGPPQLPPPAPGVHP----------------------------PA 291

Query: 295 AVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATL 354
            V  P  +   P    PA    PP P            TS  +     P A     PA  
Sbjct: 292 PVVHPPASGVHP----PAPGVHPPAPGVHPPAPGVHPPTSGVH-----PPAPGVHPPAPG 342

Query: 355 TTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPG---QAPIGNPPVGPIGGMMPPQPG 411
               A    +HP                    P PG    AP  +PP  P  G+ P  PG
Sbjct: 343 VHPPAPG--VHP--------------------PAPGVHPPAPGVHPP--PSAGVHPQAPG 378

Query: 412 I--------PQQQGMRPPMPP-HGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGG--P 460
           +        PQ  G+ PP P  H Q  G H   PG  P A P     PP V P   G  P
Sbjct: 379 VHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSA-PGVHPQPPGVHPSNPGVHP 437

Query: 461 PRP-PMGMRPPVMSQG 475
           P P P  +RPP+ S+G
Sbjct: 438 PTPMPPMLRPPLPSEG 453



 Score = 68.9 bits (167), Expect = 9e-12
 Identities = 50/132 (37%), Positives = 61/132 (46%), Gaps = 14/132 (10%)

Query: 140 PPMAQPGLPPVP----GAPGMPPG---IPPLMP-GVPPLMPGMPPVMPGMPPGMMPMGGM 191
           PP    GLPP P      P  PPG   +PP+ P G  P  P  PP +P   PG+ P   +
Sbjct: 234 PPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPV 293

Query: 192 M-PPGPGIPPLMPGM-PPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAP--Q 247
           + PP  G+ P  PG+ PP      P PG+ P T      APG+   PPAP    PAP   
Sbjct: 294 VHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV--HPPAPGVHPPAPGVH 351

Query: 248 PPVTKPLFPSAG 259
           PP      P+ G
Sbjct: 352 PPAPGVHPPAPG 363



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 48/120 (40%), Positives = 57/120 (47%), Gaps = 25/120 (20%)

Query: 134 PQQGYIPPMAQPGLPPVPGA------PGMPPGIP---PLMPGVPPLMPGMPPVMPGM--- 181
           P  G  PP   PG+ P P A      PG+ P  P   P  PGV P  PGM P  PG+   
Sbjct: 353 PAPGVHPPA--PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQ 410

Query: 182 PPGMMPMG-GMMPPGPGIPPLMPGMPPGMP-PPVPRPGIPPMTQAQAVSAPGILNRPPAP 239
           PPG+ P   G+ P  PG+ P  PG+ P  P PP+ RP +P          PG  N PP P
Sbjct: 411 PPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPS-------EGPG--NIPPPP 461



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 37/92 (40%), Positives = 45/92 (48%), Gaps = 7/92 (7%)

Query: 132 VQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGM 191
           V PQ   + P A    P  PG     PG+ P  PGV P  PG+ P  PG+ P      G+
Sbjct: 372 VHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHP---QPPGV 428

Query: 192 MPPGPGIPPLMPGMPPGMPPPVPRPG---IPP 220
            P  PG+ P  P MPP + PP+P  G   IPP
Sbjct: 429 HPSNPGVHPPTP-MPPMLRPPLPSEGPGNIPP 459



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 37/92 (40%), Positives = 44/92 (47%), Gaps = 9/92 (9%)

Query: 128 QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMP 187
           Q   V P    + P A    PP PG     PG+ P  PGV P  PG+ P     PPG+ P
Sbjct: 375 QAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHP----QPPGVHP 430

Query: 188 MG-GMMPPGPGIPPLMPGMP---PG-MPPPVP 214
              G+ PP P  P L P +P   PG +PPP P
Sbjct: 431 SNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 95/338 (28%), Positives = 120/338 (35%), Gaps = 38/338 (11%)

Query: 137 GYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGP 196
           G  PP+  PG       P  PP  P   P   P     PP          P    MPP  
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE---------PQRNRMPPPR 173

Query: 197 GIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFP 256
              P +   P  +PPPVP       T     S+P     PP P      P P  T P FP
Sbjct: 174 ---PDVGSKPDSIPPPVPS------TPRPIQSSPHNRGSPPVPGGP-RQPSPGPTPPPFP 223

Query: 257 SAGQMGTPVTSSSTASSN-SESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTT 315
             G  GT +   S   S  S S   S++   P T       + P      P+ + P+   
Sbjct: 224 --GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP--PPVGNRPSIHR 279

Query: 316 EPPKPTFPAYTQ-STASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEE 374
           E   P  P   +    ST   + S+ A P     S+P       ++S     DE   L +
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS---GNDETPRLPQ 336

Query: 375 RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG 434
           R   L      LP PG++  G  P  P     PP    P + G  PP PP  + G   + 
Sbjct: 337 RNLSLSSSTPPLPSPGRS--GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394

Query: 435 MPG--YLPGA----MPPYGQGPPMVP--PYQGGPPRPP 464
           +P    LP       P  G  PP+ P  P  G PP PP
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 82/327 (25%), Positives = 102/327 (31%), Gaps = 63/327 (19%)

Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP------PLMPGMPPVMPGMPPG 184
           P +PQ+  +PP       P P     P  IPP +P  P      P   G PPV PG P  
Sbjct: 161 PPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV-PGGPRQ 212

Query: 185 MMPMGGMMPPGPGI------------PPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGI 232
             P G   PP PG              PL    P    PP+P      +        P +
Sbjct: 213 PSP-GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271

Query: 233 LNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQA 292
            NRP      VP P P   KP  PS     TP  S+S+                      
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPS-----TPRPSASS---------------------- 304

Query: 293 QAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAK---PAASITS 349
           QA    P  +   P    P+++     P  P    S +S+T    S       P      
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364

Query: 350 KPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ 409
            P  +      S  + P   +S     +      R LP   Q P  +    P  G  PP 
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTS------RALPATPQLPSRSGVDSPRSGPRPPL 418

Query: 410 PGIPQQQGMRPPMPPHGQYGGHHQGMP 436
           P      G  PP PP        Q  P
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSP 445



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 63/273 (23%), Positives = 89/273 (32%), Gaps = 22/273 (8%)

Query: 216 PGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPP-----VTKPLFPSAGQMGTPVTSSST 270
           PG+  + QA         NR      + P   PP       KP  P +G    PV S   
Sbjct: 98  PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157

Query: 271 ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQST 329
            S   E          P       ++  PV +  +P+ S+P     PP P  P   +   
Sbjct: 158 RSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGP 217

Query: 330 ASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPR- 388
                  N   A    SI   P + ++  +    + P    +L+++    P    N P  
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277

Query: 389 -----PGQAPIGNPPVGP------IGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG 437
                P   P  N P  P           PP P  P + G  PP+PP          +P 
Sbjct: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP-PPLPPSSSGNDETPRLP- 335

Query: 438 YLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 470
                +      PP+  P + GP  PP   RPP
Sbjct: 336 --QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP 366



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/159 (25%), Positives = 59/159 (37%), Gaps = 22/159 (13%)

Query: 111 DDSDEYDDDDSAASTSFQPQPVQPQQGYI-PPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
           D++      + + S+S  P P   + G + PP ++   PPV   PG    +PP     PP
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP-----PP 383

Query: 170 LMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSA 229
                P    G     +P    +P   G+     G  P +PP  P  G PP         
Sbjct: 384 -----PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438

Query: 230 PGILNRPPA----------PTATVPAPQPPV-TKPLFPS 257
            G  + P            P + +P P+P V T   +PS
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477



 Score = 35.8 bits (81), Expect = 0.088
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 36/126 (28%)

Query: 376 RAQLPKYQRNLPRPGQAPIGNPPVG---PIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHH 432
           R+  P+ QRN   P +  +G+ P     P+     P    P  +G  PP+P     GG  
Sbjct: 158 RSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS-PPVP-----GGPR 211

Query: 433 QGMPGYLPGAMP---------------------PYGQGPPMVPPYQGG------PPRPPM 465
           Q  PG  P   P                     P+   PP+ P           PP PP+
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271

Query: 466 GMRPPV 471
           G RP +
Sbjct: 272 GNRPSI 277


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 95/338 (28%), Positives = 120/338 (35%), Gaps = 38/338 (11%)

Query: 137 GYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGP 196
           G  PP+  PG       P  PP  P   P   P     PP          P    MPP  
Sbjct: 123 GSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPE---------PQRNRMPPPR 173

Query: 197 GIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFP 256
              P +   P  +PPPVP       T     S+P     PP P      P P  T P FP
Sbjct: 174 ---PDVGSKPDSIPPPVPS------TPRPIQSSPHNRGSPPVPGGP-RQPSPGPTPPPFP 223

Query: 257 SAGQMGTPVTSSSTASSN-SESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTT 315
             G  GT +   S   S  S S   S++   P T       + P      P+ + P+   
Sbjct: 224 --GNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPP--PPVGNRPSIHR 279

Query: 316 EPPKPTFPAYTQ-STASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEE 374
           E   P  P   +    ST   + S+ A P     S+P       ++S     DE   L +
Sbjct: 280 EAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSS---GNDETPRLPQ 336

Query: 375 RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG 434
           R   L      LP PG++  G  P  P     PP    P + G  PP PP  + G   + 
Sbjct: 337 RNLSLSSSTPPLPSPGRS--GPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRA 394

Query: 435 MPG--YLPGA----MPPYGQGPPMVP--PYQGGPPRPP 464
           +P    LP       P  G  PP+ P  P  G PP PP
Sbjct: 395 LPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPP 432



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 82/327 (25%), Positives = 102/327 (31%), Gaps = 63/327 (19%)

Query: 131 PVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP------PLMPGMPPVMPGMPPG 184
           P +PQ+  +PP       P P     P  IPP +P  P      P   G PPV PG P  
Sbjct: 161 PPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV-PGGPRQ 212

Query: 185 MMPMGGMMPPGPGI------------PPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGI 232
             P G   PP PG              PL    P    PP+P      +        P +
Sbjct: 213 PSP-GPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271

Query: 233 LNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQA 292
            NRP      VP P P   KP  PS     TP  S+S+                      
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPS-----TPRPSASS---------------------- 304

Query: 293 QAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAK---PAASITS 349
           QA    P  +   P    P+++     P  P    S +S+T    S       P      
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSER 364

Query: 350 KPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQ 409
            P  +      S  + P   +S     +      R LP   Q P  +    P  G  PP 
Sbjct: 365 PPPPVRDPPGRSGPLPPPPPVSRNGSTS------RALPATPQLPSRSGVDSPRSGPRPPL 418

Query: 410 PGIPQQQGMRPPMPPHGQYGGHHQGMP 436
           P      G  PP PP        Q  P
Sbjct: 419 PPDRPSAGAPPPPPPSTSIRNGFQDSP 445



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 63/273 (23%), Positives = 89/273 (32%), Gaps = 22/273 (8%)

Query: 216 PGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPP-----VTKPLFPSAGQMGTPVTSSST 270
           PG+  + QA         NR      + P   PP       KP  P +G    PV S   
Sbjct: 98  PGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGH 157

Query: 271 ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQST 329
            S   E          P       ++  PV +  +P+ S+P     PP P  P   +   
Sbjct: 158 RSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGP 217

Query: 330 ASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPR- 388
                  N   A    SI   P + ++  +    + P    +L+++    P    N P  
Sbjct: 218 TPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSI 277

Query: 389 -----PGQAPIGNPPVGP------IGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG 437
                P   P  N P  P           PP P  P + G  PP+PP          +P 
Sbjct: 278 HREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP-PPLPPSSSGNDETPRLP- 335

Query: 438 YLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPP 470
                +      PP+  P + GP  PP   RPP
Sbjct: 336 --QRNLSLSSSTPPLPSPGRSGPLPPPPSERPP 366



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 40/159 (25%), Positives = 59/159 (37%), Gaps = 22/159 (13%)

Query: 111 DDSDEYDDDDSAASTSFQPQPVQPQQGYI-PPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
           D++      + + S+S  P P   + G + PP ++   PPV   PG    +PP     PP
Sbjct: 329 DETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPP-----PP 383

Query: 170 LMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSA 229
                P    G     +P    +P   G+     G  P +PP  P  G PP         
Sbjct: 384 -----PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIR 438

Query: 230 PGILNRPPA----------PTATVPAPQPPV-TKPLFPS 257
            G  + P            P + +P P+P V T   +PS
Sbjct: 439 NGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPS 477



 Score = 35.8 bits (81), Expect = 0.088
 Identities = 33/126 (26%), Positives = 45/126 (35%), Gaps = 36/126 (28%)

Query: 376 RAQLPKYQRNLPRPGQAPIGNPPVG---PIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHH 432
           R+  P+ QRN   P +  +G+ P     P+     P    P  +G  PP+P     GG  
Sbjct: 158 RSGPPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGS-PPVP-----GGPR 211

Query: 433 QGMPGYLPGAMP---------------------PYGQGPPMVPPYQGG------PPRPPM 465
           Q  PG  P   P                     P+   PP+ P           PP PP+
Sbjct: 212 QPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPV 271

Query: 466 GMRPPV 471
           G RP +
Sbjct: 272 GNRPSI 277


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 77.4 bits (189), Expect = 3e-14
 Identities = 89/356 (25%), Positives = 120/356 (33%), Gaps = 38/356 (10%)

Query: 127 FQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPP---GIPPLMPGVPPLMPGMPPVMPGMPP 183
           F P P  P Q    P A P + P    P   P     PPL   VPP  P  PP+ P   P
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATP 722

Query: 184 GMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATV 243
                  +  P   +PP  P  PP  P   P P +PP+  A        L  PP+P A++
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP------LQVPPSPPASL 776

Query: 244 PAPQPPVTKPLFPSAGQMGTPVTSS--STASSNSESLSASSKALFPSTAQAQAAVQGPVG 301
             P  P+ KP   +   + TP   +  S  +S       S  A  P +  A    Q P  
Sbjct: 777 --PMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP-- 832

Query: 302 TDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP--AASITSKPATLTTTSA 359
               P+ + P     P  P  P         T   +++ + P    ++   P    + S 
Sbjct: 833 ----PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888

Query: 360 TSKLIHPD---EDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQ 416
           +S L  PD      S      +L  Y       G A    PP   +    P        +
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSG--PEGGAAASPPPDAELAACHP----AAWSR 942

Query: 417 GMRPPMPPHGQYGGHHQGMPGYLPGAMPPY-----GQGPPMVPPYQGG-PPRPPMG 466
           G  PP+   G  G      P   PG+          +GP    P  G   P P  G
Sbjct: 943 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 66/240 (27%), Positives = 91/240 (37%), Gaps = 17/240 (7%)

Query: 123 ASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPG--VPPLMPGMPPVMPG 180
           AS    P    P Q   P +A P L   P  P  PP  P   P    PP +   P  +P 
Sbjct: 681 ASPPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQ-AVSAPGILNRPPAP 239
            PP   PM     P P +PPL+   PP   PP P   +P    A+    AP  L  PP  
Sbjct: 740 SPPASPPMSPSATPPPRVPPLLAA-PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798

Query: 240 TATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP 299
               P    P   P  PSA     P++  +T    +  + A+     P +  A   +Q P
Sbjct: 799 ALPSPPASFPGQAPFSPSA---SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 855

Query: 300 VGTDFKPLNSTPATTTEPPKPTF-----PAYTQSTASTTSTTNSTAAKPAASITSKPATL 354
                +P    P T+   P+ T      P    S + +++ +    A  ++S TS P  L
Sbjct: 856 ----RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 911



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 101/352 (28%), Positives = 136/352 (38%), Gaps = 46/352 (13%)

Query: 143 AQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLM 202
           A+P  PP   A  +P  +PP  P   PL P  PP  P  PP +      +P  P  PP  
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPL-PLAPP-SPSAPPSLQ----TLPSPPATPPSQ 367

Query: 203 PGMPPGM-PPPVPRP----GIPPMTQAQAVSAPGILNRPPAP--------TATVPAPQPP 249
              PP M  PP+  P     IPP+    ++++P  L  PP+P        T ++ +P   
Sbjct: 368 --APPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS-LQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 250 VTKP-LFPSAGQMGTPVTS-SSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPL 307
            T   L  S  Q    +TS S  AS+  +S    +    P++   Q ++   V     PL
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL 484

Query: 308 NSTPATTTEPPKPTFP-AYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS--KLI 364
              P           P A   S       T S+ A P  S+ + PA+LTT    +   L 
Sbjct: 485 TIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP--SLQTPPASLTTPPLENLPSLA 542

Query: 365 HPDEDISLEERRAQL-PKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMP 423
            P     L+   A L   +    P P   P+  PP      +  P P  P      PP  
Sbjct: 543 PP----PLQTASAPLTTPHLETPPCPAPCPLQAPP----SPLTTPPPETPSSIATPPPQA 594

Query: 424 PHGQYGGHHQGMPG--YLPGAMPPYGQGPP--MVPPYQGGPPRPPMGMRPPV 471
           P        QG+P     P A PP  Q PP   +PP Q  PP PP    PP+
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPP-PQAPPXLALPPLQ-APPSPPAS--PPL 642



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 96/398 (24%), Positives = 133/398 (33%), Gaps = 76/398 (19%)

Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMP- 187
           P P+ P      P A P L  +P  P  PP   P     PP+    PP +  +PP  +P 
Sbjct: 340 PLPLAPPS----PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQ--APPSLQTIPPIQVPH 393

Query: 188 ----MGGMMPPGP-GIPPLMPGMPPGMPPPVPRPGI----PPMTQAQAVSAPGILNRPP- 237
                    PP P  +  L      G P            P  TQA   S     + PP 
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453

Query: 238 APTATVP---APQPPVTKPLFPSAGQMGTPVT---SSSTASSNSESLSASSKALFPSTAQ 291
           +P    P      PP+   L P+   + +P+T     + +S  S S  A   +L     +
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513

Query: 292 AQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQ---STASTTSTTNSTAAKPAAS-- 346
            Q+++  P       L + PA+ T PP    P+       TAS   TT      P  +  
Sbjct: 514 TQSSLAPP------SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC 567

Query: 347 -ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY-----QRNLPRPGQAPIGNPP-- 398
            + + P+ LTT         P+   S+     Q P        + LP P  +P+  PP  
Sbjct: 568 PLQAPPSPLTTPP-------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQ 620

Query: 399 ------------------VGPIGGMMPPQPGIPQ-------QQGMRPPMPPHGQYGGHHQ 433
                               P+  +  P P  P        Q    PP  P  Q      
Sbjct: 621 APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 680

Query: 434 GMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPV 471
             P   P A PP    P +  P    PP PP    PP+
Sbjct: 681 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPM 716



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 90/374 (24%), Positives = 121/374 (32%), Gaps = 58/374 (15%)

Query: 140 PPMAQPGL--PPVPGAPGMP--------PGIPPLMPGVPPLM-PGMPPVMPGMPPGMMP- 187
           PP A P L  PP+ G P  P        P  PP +  +PPL  P  PP  P + P   P 
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL-ALPPLQAPPSPPASPPLSPLATPS 649

Query: 188 -----------MGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
                      +     P P  P   P  PP  PP  P    PP     +++AP  L  P
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-SATPPSQAPPSLAAPP-LQVP 707

Query: 237 PAPTATVP----------APQPPVTKPL-FPSAGQMGTPVTSSSTASSNSESLSASSKAL 285
           P+P A+ P          AP P    PL  P +     P++ S+T       L A+    
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 286 FPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAA 345
            P +  A      P+    KP    P     PP    P      +   S        P+A
Sbjct: 768 VPPSPPASL----PMSPLAKPPPQAPPALATPPLQALP------SPPASFPGQAPFSPSA 817

Query: 346 SITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPG-QAPIGNP--PVGPI 402
           S+   P       A   L  P   +      +   +  R  P PG    +  P   +   
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877

Query: 403 GGMMPPQPGIPQQQGMRPPMPPHG--------QYGGHHQGMPGYLPGAMPPYGQGPPMVP 454
            G  PP    P      P +  H         +  G+  G  G    + PP  +     P
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937

Query: 455 PYQGGPPRPPMGMR 468
                 P PP+  R
Sbjct: 938 AAWSRGPAPPLAFR 951



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 87/338 (25%), Positives = 115/338 (34%), Gaps = 28/338 (8%)

Query: 134 PQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPL--MPGMPPVMP-GMPPGMMPMGG 190
           P Q    P+  P  P  P +   PP   P     PPL  +P  PP+ P   PP   P   
Sbjct: 568 PLQAPPSPLTTPP-PETPSSIATPPPQAPPALASPPLQGLPS-PPLSPLATPPPQAPPXL 625

Query: 191 MMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPV 250
            +PP    PP  P  PP  P   P P  P       + AP   + PP+P    P   PP 
Sbjct: 626 ALPPLQA-PPSPPASPPLSPLATPSPQAPNALAVHLLQAP--FSPPPSPPVQAPF-SPPA 681

Query: 251 TKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNST 310
           + P+ PSA     P  +  + ++    +  S  A  P +  A    Q P      P  + 
Sbjct: 682 SPPVSPSA---TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP------PPLAA 732

Query: 311 PATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDI 370
           P     P  P  P  + S           AA P     S PA+L  +            +
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 371 SLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQG----MRPPMPPHG 426
           +    +A LP    +   PGQAP       P+  +  P P  P          PP PP  
Sbjct: 793 ATPPLQA-LPSPPASF--PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 427 QYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPP 464
                 +  P   P        GP +      GPP PP
Sbjct: 850 PTLQAPRRPPTPGPDTSV---SGPRLTLALAPGPPPPP 884



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 97/371 (26%), Positives = 129/371 (34%), Gaps = 58/371 (15%)

Query: 146 GLPPVPGAPGMPP--GIPPLMPGVPPLMPGMPPVMPGMPP-GMMPMGGMMPPGPGIPPLM 202
           G P  P  P  P   G+  L P  P + P      P + P    P+    P G    P+ 
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRP--PQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVP 318

Query: 203 PG------MPPGMPP----PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPP-VT 251
           P       +P  +PP      P P  PP     + SAP  L   P+P AT P+  PP +T
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPP-----SPSAPPSLQTLPSPPATPPSQAPPSMT 373

Query: 252 KPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP---VGTDFKPLN 308
            P   +   + T        S  S SL A    L  S+ QA  ++  P       F  ++
Sbjct: 374 TPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS 433

Query: 309 --STPATTTEPPKPT-----FPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATS 361
              T A+ T P +P       P      +   S    T+  PA S  S P T+    A S
Sbjct: 434 PRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493

Query: 362 KLIHPDEDISLEERRAQLPKYQRNLPRPG----QAPIGNPPVGPIGGMMPPQPGIPQQQG 417
            L        L        + Q +L  P      A +  PP+  +  + PP    P Q  
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPP----PLQTA 549

Query: 418 MRPPMPPHGQYGGHHQGMPGYLPG--------------AMPPYGQGPPMV--PPYQG--G 459
             P   PH +        P   P               A PP  Q PP +  PP QG   
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP-PQAPPALASPPLQGLPS 608

Query: 460 PPRPPMGMRPP 470
           PP  P+   PP
Sbjct: 609 PPLSPLATPPP 619



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 59/223 (26%), Positives = 82/223 (36%), Gaps = 45/223 (20%)

Query: 124 STSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGM---PPGIPPLMPGVPPLMPG------M 174
           S +  P  V P     PPM+    PP    P +   P  +PP  P  PP+ P       +
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757

Query: 175 PPVM-------PGMPPGMMPMGGMMPPGPGIPPLM-----------PGMPPGMPPPVPRP 216
           PP++       P  PP  +PM  +  P P  PP +           P   PG  P  P  
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817

Query: 217 GIP------PMTQAQAVSAPGILNRPPAPTAT----------VPAPQPPVTKPLFPSAGQ 260
            +P      P  QA  V A  +L  PP+P A+           P P   V+ P    A  
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 877

Query: 261 MGTPVTSSSTASS--NSESLSASSKALFPSTAQAQAAVQGPVG 301
            G P   S + SS  +   L+  S +   +  + +    GP G
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920



 Score = 62.4 bits (150), Expect = 9e-10
 Identities = 84/376 (22%), Positives = 124/376 (32%), Gaps = 50/376 (13%)

Query: 123 ASTSFQPQPVQPQQGYI---PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMP 179
           A+TS     +Q    ++   P   Q  L         PP  PPL    P  +P  PP+  
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ--APLSLPASPPLQT 471

Query: 180 GMPPGMMPMGGMM---------------PPGPGIPPLMPGM-------PPGMPPPVPRPG 217
            + P + P+   +               P  P    +MP +       PP +  P     
Sbjct: 472 SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLT 531

Query: 218 IPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSES 277
            PP+    +++ P      P  TA+ P   P +  P  P+   +  P +  +T    + S
Sbjct: 532 TPPLENLPSLAPP------PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPS 585

Query: 278 LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 337
             A+     P  A A   +QG       PL + P     PP    P      +   S   
Sbjct: 586 SIATPPPQAPP-ALASPPLQGLPSPPLSPLATPPPQA--PPXLALPPLQAPPSPPASPPL 642

Query: 338 STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP--IG 395
           S  A P+    +  A     +  S    P   +         P    +   P QAP  + 
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSP--PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 700

Query: 396 NPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
            PP+      +PP P  P    M P   P  Q        P  +P + P     PPM P 
Sbjct: 701 APPL-----QVPPSP--PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA---SPPMSPS 750

Query: 456 YQGGPPRPPMGMRPPV 471
               P  PP+   PP+
Sbjct: 751 ATPPPRVPPLLAAPPL 766



 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 86/348 (24%), Positives = 113/348 (32%), Gaps = 46/348 (13%)

Query: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG 208
           P   APG+    PP  P  PP         P  P  +  +G     G        G   G
Sbjct: 17  PAARAPGLLTPRPPGSPRPPP---------PVTPAALRVLGAAGAVGRKPLAERAGGIGG 67

Query: 209 MPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSS 268
              P   P   P T++   S+    +RPPA      AP    T P          PV+S 
Sbjct: 68  ATIPESAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSP---------GPVSSP 117

Query: 269 STASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQS 328
             AS  +       K L  S  +  A  +         L++     T  P P  P+   +
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177

Query: 329 TASTTSTTNSTAAKPAASITSKPATL-TTTSATSKLIHPDEDISLEERRAQLPKYQRNLP 387
             S  + T     +PA S   +P T     S +S   H   + S   RR   P     L 
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR--PSAGGGLQ 235

Query: 388 RPGQ-------APIGNPP-VGPIGGMMPPQPGIPQQ------QGMRPP-MPPHGQYGGHH 432
           RP          P+ +P   GP     P  P  P Q      Q +RPP + P  +     
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295

Query: 433 QGMPGYLPGAMP-PYGQGPPMVPPYQGG--------PPRPPMGMRPPV 471
            G     P A P P G     VPP            PP PP+    P+
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 85/369 (23%), Positives = 123/369 (33%), Gaps = 43/369 (11%)

Query: 122 AASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLM-PGVPPLMPGMPPVMPG 180
           A S   +P    P++            P P A   P     L  P    L     P+   
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
              G    G    P     P   G+    PP V  P          +S+  +    P+ T
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGT 312

Query: 241 ATVPAPQPP-VTKPL---FPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAV 296
              P P P     PL    P +  + TP+  +  + S   SL        P+T  +QA  
Sbjct: 313 KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP--PATPPSQA-- 368

Query: 297 QGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTT 356
             P      P+ + P+  T PP        Q   S TS +      P A ++S  AT + 
Sbjct: 369 --PPSMTTPPMQAPPSLQTIPP-------IQVPHSLTSPSLQAPPSPLA-LSSLQATTSL 418

Query: 357 TSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV-GPIGGMMPPQPGIPQQ 415
            S T +  H    +S  + +A L     +  RP   P  +PP+  P+   +P  P  P Q
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL----TSPSRPASTPPDSPPLQAPLS--LPASP--PLQ 470

Query: 416 QGMRPPMPPHGQYGGHH-----QGMPGYLPGA------MPPYGQGPPMVPPYQGGPP--- 461
             + P + P       H       +  + P A      MPP      + PP    PP   
Sbjct: 471 TSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASL 530

Query: 462 -RPPMGMRP 469
             PP+   P
Sbjct: 531 TTPPLENLP 539


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 110/407 (27%), Positives = 139/407 (34%), Gaps = 102/407 (25%)

Query: 98   EQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQ-GYIPPMAQPGLPP---VPGA 153
            +++ QE   K+QQ    +     SA  T   P P QP   G +P    P  PP    PGA
Sbjct: 648  QRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPKALYPGA 707

Query: 154  PGMPPGIPP---------LMPGVPP-LMPGMPPV---MPGM-PPGMMPM------GGMMP 193
             G PP +PP         + P V P L+ G PP+    PG+ P G++P       G    
Sbjct: 708  LGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGGSSSE 767

Query: 194  PGPGIPPLM---PGMPPGMP------------PPVPRPGIPPMTQAQAVSAPGILNRPPA 238
            P     P M    G PP  P            P  PRP   P+ QA      G+ +  P 
Sbjct: 768  PFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSETP- 826

Query: 239  PTATVPAPQPP---VTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAA 295
                 P P PP    + P FP  G  G P++                   FP        
Sbjct: 827  -----PVPPPPPYLASYPGFPENGAPGPPISR------------------FPLEEPGPRP 863

Query: 296  VQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS---KPA 352
            +  P G+D      TP    EPPK       + TA  T        KPA  + S    P 
Sbjct: 864  LPWPPGSDEVAKIQTPPPKKEPPK-------EETAQLTGP--EAGRKPARGVGSGGQGPP 914

Query: 353  TLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGI 412
                 S T     P    S    R  +P  +   P     PI  PP       +PP+   
Sbjct: 915  PPRRESRTETRWGPRPGSS----RRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPK--- 967

Query: 413  PQQQGMRPPMPP--------HGQYGGHHQGMPGYLPGAMPPYGQGPP 451
            P +QG   P PP         G+ GG         P   PP G   P
Sbjct: 968  PLEQGDETPKPPKPDPLKITKGKLGG---------PKETPPNGNLSP 1005



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 72/277 (25%), Positives = 100/277 (36%), Gaps = 37/277 (13%)

Query: 184 GMMPMGGMMPPGPGIPPLMP---GMPPGMPPPVPRPGI---PPMTQAQAVSAPGILNRPP 237
           G + +   MPP   +P L     G  P +   VP+ G        Q+   S+     +PP
Sbjct: 48  GKVAIARRMPPPANLPSLKAENKGNDPNVSL-VPKDGTGWASKQEQSDPKSSDASTAQPP 106

Query: 238 APTATVPAPQPPVT-KPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAV 296
             +  +PA Q P + +P  P A    TP+  S   S                   AQA+V
Sbjct: 107 E-SQPLPASQTPASNQPKRPPAAPENTPLVPSGVKS------------------WAQASV 147

Query: 297 QGPVGTDFKPLNSTPATTTEPPKPTFPAY-TQSTASTTSTTNSTAAKPAASITSKPATLT 355
                 D    +S  +  +    PT  A   Q  A+    +   ++ P  S+  + +T  
Sbjct: 148 THGAHGDGGRASSLLSRFSREEFPTLQAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTW 207

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQ 415
                     PDE   LE   ++L  +  + PR G  P G P   P  GMMPP    P  
Sbjct: 208 RDGGGRG---PDE---LEGPDSKL--HHGHDPRGGLQPSGPPQFPPYRGMMPPFM-YPPY 258

Query: 416 QGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPM 452
               PP  P G Y       P   P    P G GPPM
Sbjct: 259 LPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPM 295



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 91/417 (21%), Positives = 118/417 (28%), Gaps = 71/417 (17%)

Query: 93  RRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPG 152
           RR   E++ QE ++    +     D+   A     + +P  P          P  P  P 
Sbjct: 470 RREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAP----------PAAPSTPA 519

Query: 153 APGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPP 212
            P   P   P  P  PP     P   P  P    P      PG    P +          
Sbjct: 520 PPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTL---------- 569

Query: 213 VPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQ---PPVTKPLFPSAGQMGTPVTSSS 269
           V   G    T + +  A  +   P  P+   P P    PP T P  P     G  +  + 
Sbjct: 570 VSGGGSTSSTSSGSFEASPV--EPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTR 627

Query: 270 TASSNSESLSASSKAL---FPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYT 326
              S         K+L   F    Q Q   Q       +    +   T  PP P  P   
Sbjct: 628 QPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTL 687

Query: 327 QST-ASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
            +  A         A  P A     P           +I P  D  L + R  L  Y   
Sbjct: 688 GAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPG 747

Query: 386 LPRPGQAP------------------------IGNPPVGP----IGGMMPPQPGIPQQQG 417
           +   G  P                         G PPV P    +G +    P  P    
Sbjct: 748 VHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEP---- 803

Query: 418 MRPPMPPHGQYGGH-HQGMPGYLPGAMPPYGQGPPMVPPYQG----GPPRPPMGMRP 469
            RP   P  Q      +GM    P   PP    PP +  Y G    G P PP+   P
Sbjct: 804 -RPLTSPLRQAADEDDKGMRSETPPVPPP----PPYLASYPGFPENGAPGPPISRFP 855



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 109/512 (21%), Positives = 161/512 (31%), Gaps = 163/512 (31%)

Query: 66   PNAIPGRTDIELEIYGMEGIPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAAST 125
            P A  GRT  E      EG   +++ +RRR           ++  +   E  + D A S 
Sbjct: 1076 PPAPRGRTASETR---SEGSEYEEIPKRRR-----------QRGSETGSETHESDLAPSD 1121

Query: 126  SFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGM 185
               P P   ++G +  +  P  PP PGAP  P                        P   
Sbjct: 1122 KEAPTP---KEGTLTQV--PLAPPPPGAPPSPA-----------------------PARF 1153

Query: 186  MPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPA 245
               GG +    G+P    G   G PPP   PG  P  ++ A   P        PT  +P 
Sbjct: 1154 TARGGRVFTPRGVPSRR-GRGGGRPPPQVCPGWSPPAKSLAPKKP--------PTGPLPP 1204

Query: 246  PQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP------ 299
             + P+ + L P  G + +PV    +   ++  +    +       +AQ   + P      
Sbjct: 1205 SKEPLKEKLIP--GPL-SPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLK 1261

Query: 300  -------VGTDFKPLNSTPATTTEPPK-----PTFPAYTQSTASTTSTTNSTA------- 340
                    G++ KP  + PA+   P +        PA  ++ A +   +N  +       
Sbjct: 1262 QERENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321

Query: 341  --AKPAASITSK--------PATLTTTSAT-------------------SKLIHPDEDIS 371
              A  ++  TS+        P  L T  A                      L    +D+S
Sbjct: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLS 1381

Query: 372  LEERRAQLPKYQRNLPRPGQ----------------APIGNPPVG---------PIGGMM 406
                 +Q P  +R   RPG                  P G    G         P     
Sbjct: 1382 KRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSR 1441

Query: 407  PPQ---PGIPQQQGMRPPMPP------------HGQYGGHHQGMPGY--------LPGAM 443
            PP+   PG+P      PP PP            H    G  Q +            PG  
Sbjct: 1442 PPEERPPGLP-----LPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGH 1496

Query: 444  PPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQG 475
            P +  G P  P  QG  PRPP    P  ++ G
Sbjct: 1497 PRHKPGLPQAP--QGPSPRPPTRYEPQRVNSG 1526



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 9/80 (11%)

Query: 154 PGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPV 213
           P  PP  PP    +PP M   PP +P  PP   P G    P P  P   P +        
Sbjct: 237 PSGPPQFPPYRGMMPPFM--YPPYLP-FPPPYGPQGPYRYPTPDGPSRFPRVAG------ 287

Query: 214 PRPGIPPMTQAQAVSAPGIL 233
           PR   PPM   + V  P IL
Sbjct: 288 PRGSGPPMRLVEPVGRPSIL 307



 Score = 39.7 bits (91), Expect = 0.006
 Identities = 78/329 (23%), Positives = 108/329 (32%), Gaps = 68/329 (20%)

Query: 203 PGMPPGMPPPVPRPGIPPMTQAQAVS--APGILNRPPAPTATVPAPQ---PPVTKPLFPS 257
           P   PG  PP P+P +PP  +  A +   PG       P    PAP+       +    S
Sbjct: 399 PETEPG--PPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQS 456

Query: 258 AGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPA----- 312
           + ++   V  +       E      +    + A+    +    G   K L + PA     
Sbjct: 457 SSEISLAVERARRRREEEERRMQEERR--AACAEKLKRLDEKFGAPDKRLKAEPAAPPAA 514

Query: 313 -TTTEPPK------PTFPAYTQSTASTTST-TNSTAAKPAASITSKPATLT--------- 355
            +T  PP       P  PA   ++A T  T     A  P A  T  P             
Sbjct: 515 PSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGG 574

Query: 356 TTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPP--QP--- 410
           +TS+TS        +  +    + P+    +P P   P+  P V P G  + P  QP   
Sbjct: 575 STSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPV--PKVEPKGDGIGPTRQPPSQ 632

Query: 411 --GIPQQQGMRPP------------MPPHGQYGGHHQGMPGYLP-----------GAMP- 444
             G P+ Q   PP                 Q+  H QG     P           GA+P 
Sbjct: 633 GLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPA 692

Query: 445 PYGQGPPMVPPYQGG----PPRPPMGMRP 469
           P    PP    Y G     PP PPM   P
Sbjct: 693 PQAPPPPPKALYPGALGRPPPMPPMNFDP 721



 Score = 36.6 bits (83), Expect = 0.052
 Identities = 89/348 (25%), Positives = 114/348 (32%), Gaps = 71/348 (20%)

Query: 175  PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGM-PPGMPPPVPRPGIPPMTQAQAVSAPGIL 233
            PP  PG   G  P+  +   GP      PG  PP  PPP P  G       +    PG +
Sbjct: 1683 PPKRPG---GSSPLNAVPCEGP------PGSEPPRRPPPAPHDGDRKELPREQPLPPGPI 1733

Query: 234  NRPPA---PTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTA 290
                +      T P P  P  +P  P   Q GT    S       +SL A  +     TA
Sbjct: 1734 GTERSQRTDRGTEPGPIRPSHRPGPPV--QFGTSDKDSDLRLVVGDSLKAEKEL----TA 1787

Query: 291  QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTF------PAYTQSTASTTSTTNSTAAKPA 344
                A+  PV  D++ L S  A + EP           P  + S           +A P+
Sbjct: 1788 SVTEAI--PVSRDWELLPSA-AASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPS 1844

Query: 345  ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVG---- 400
            +S  S  A  +     S    P    SL   R+Q P Y    P P  A +    +     
Sbjct: 1845 SSQISGGAMDSQLHPNSGGFRPGTP-SLHPYRSQ-PLYLPPGPAPPSALLSGLALKGQFL 1902

Query: 401  -------------PIGGMMPPQPGIPQQQGMRP-PMP-------------PHGQYGGHHQ 433
                         P GG++ P P         P P+P             P   Y    Q
Sbjct: 1903 DFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSDFYSTPLQ 1962

Query: 434  --GMPGYLPGAMPPYGQGPPMV----PPYQGG--PPRPPMGMRPPVMS 473
              G  G+LP   P      PMV    P    G  PP PP    PP +S
Sbjct: 1963 PGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPA--PPPLS 2008



 Score = 34.3 bits (77), Expect = 0.26
 Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 23/149 (15%)

Query: 176  PVMPGMPPGMMPMGG-----MMPPGPGIPPLMP--GMPPGMPPPVPRPGIPPMTQAQAVS 228
            P+ PG   G +P G      ++P      P++    +PP  PP  P   + P+    A+ 
Sbjct: 1960 PLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFGSLPPAPPPAPPPLSLLPV--GPALQ 2017

Query: 229  APGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
             P +  RPP   AT   P P   +P FP++  +G             +    SS    P 
Sbjct: 2018 PPSLAVRPPPAPATRVLPSP--ARP-FPAS--LGRAELHPVELKPFQDYQKLSSNLGGPG 2072

Query: 289  TAQAQAAVQGPVGTDFKPLNS----TPAT 313
            +++       P G  F  LNS    TP+T
Sbjct: 2073 SSRTP-----PTGRSFSGLNSRLKATPST 2096



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 28/162 (17%)

Query: 120  DSAASTSFQPQPVQP--QQGYIP---PMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGM 174
            D  + + F   P+QP  Q G++P   P  Q  LP V     +P      +P  PP  P  
Sbjct: 1949 DLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQ--LPVVNFGSLPPAPP--PAP 2004

Query: 175  PPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILN 234
            PP+       ++P+G         P L P      PPP P   + P   + A   P  L 
Sbjct: 2005 PPL------SLLPVG---------PALQPPSLAVRPPPAPATRVLP---SPARPFPASLG 2046

Query: 235  RPPA-PTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNS 275
            R    P    P              G   TP T  S +  NS
Sbjct: 2047 RAELHPVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNS 2088



 Score = 30.0 bits (66), Expect = 4.8
 Identities = 26/91 (28%), Positives = 35/91 (38%), Gaps = 27/91 (29%)

Query: 375 RRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG 434
           ++   P  +   P+   A    PP    G   PP P        +PP+PP       H+G
Sbjct: 376 KKGNSPNSEPPTPKTAWAETSRPPETEPG---PPAP--------KPPLPPP------HRG 418

Query: 435 MPGYLPGAMPPYGQGPPMVPPYQGGPP-RPP 464
             G           GPP   P +GGPP +PP
Sbjct: 419 PAG---------NWGPPGDYPDRGGPPCKPP 440


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 76.3 bits (186), Expect = 6e-14
 Identities = 107/420 (25%), Positives = 149/420 (35%), Gaps = 95/420 (22%)

Query: 120 DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPP-----LMPGVPPLMP-- 172
           D   S  F P  ++  Q        P  PP     G PP + P     +M G PP     
Sbjct: 7   DGGESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPRPP 66

Query: 173 -GMPPVMPGMPPGMMPMGGMMPP-GP---GIPPLMPGMPPGMPPP---VPRPGIPPMTQA 224
            G PP  P MPP M P GG+ PP GP     PP MP     MPPP   +  PG+PP+T  
Sbjct: 67  FGRPPFDPNMPP-MPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAP 125

Query: 225 QAVSAP-----GILNRPP--------APTATVPAPQPPVTK--------PLFPSAGQMGT 263
              + P      + N+ P        A T      +P   K        P+  +  Q+  
Sbjct: 126 GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQA 185

Query: 264 PVTSSSTASSNSES-------------------------LSASSKALFPSTAQAQAAVQG 298
              + + A + +++                           A ++A   + AQAQA VQ 
Sbjct: 186 QAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQA 245

Query: 299 PVGTDFKPL---NSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLT 355
            V    +      STP  TT  P P     T S+  +++T+ +T A   A   S P T  
Sbjct: 246 QVQAQVQAQAVGASTP--TTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQD 303

Query: 356 TT--------------SATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV-- 399
            T              S  +    P + +     +   P    ++P+P  A    PPV  
Sbjct: 304 QTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMV 363

Query: 400 ----GPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPP 455
                P+ GM  P PG+   Q +  P               G LPG  PP     PM+ P
Sbjct: 364 PPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVA-----TTKTGVLPGMAPPI---VPMIHP 415



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 53/244 (21%), Positives = 87/244 (35%), Gaps = 47/244 (19%)

Query: 149 PVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPG 208
           P P    +PP +P  +P     +P  PPVM  +PP  +P+ GM                 
Sbjct: 333 PQPHPQTLPPAVPHSVPQPTTAIPAFPPVM--VPPFRVPLPGM----------------- 373

Query: 209 MPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVT-- 266
              P+P PG+  M   Q VS P +       T  +P   PP+   + P      +P T  
Sbjct: 374 ---PIPLPGVAMM---QIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLA 427

Query: 267 SSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYT 326
            ++  S  +E  +A  K  + +    ++  + P   + K          EP K      +
Sbjct: 428 GATAVSEWTEYKTADGKTYYYNNRTLESTWEKP--QELKEKEKLEEKIKEPIKEP----S 481

Query: 327 QSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL 386
           +      +       +P   I  +P               +E+++ EE+ AQ  K     
Sbjct: 482 EEPLPMETEEEDPKEEPIKEIKEEP--------------KEEEMTEEEKAAQKAKPVATA 527

Query: 387 PRPG 390
           P PG
Sbjct: 528 PIPG 531


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 107/378 (28%), Positives = 133/378 (35%), Gaps = 88/378 (23%)

Query: 129 PQPVQPQQGYIPPMAQPGLP--PVPGAPGMPPGIPPLMPGVPPLM---PGMPPVMPGMPP 183
           PQ +     Y  P A PGLP   VP AP  PP +    P   P M   P +PP    MP 
Sbjct: 663 PQSLPSLGAYQQPTAAPGLPVGSVP-APACPPSLQQHFPD--PAMSFAPVLPPPSTPMPT 719

Query: 184 GMMPMGGMMPPGPGIPPLMPGMP--------PGMP-PPVPRPGIPP-MTQAQAVSAPGIL 233
           G    G   PPG   PPL    P        P +P  PVP P +PP +  A  V AP  L
Sbjct: 720 GP---GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVP-PHLPPYLAPASQVGAPAQL 775

Query: 234 N------RPPAPTATVPAPQPP--VTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKAL 285
                   P  P A VP   PP  V  P+ P AG  G P                     
Sbjct: 776 KPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLP--------------------- 814

Query: 286 FPSTAQAQAAVQGPVGTD--FKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP 343
            P+      A   PV     F P    P+     P P  PA             +  A P
Sbjct: 815 -PALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP-PASPALPLQAVKLPHPPGAPLAMP 872

Query: 344 AASIT-SKPATLTTTSATSKLIHPDEDISLEERRAQLPK---YQRNLPRPGQAPIGNPPV 399
             +I  + PAT+   +     +     +S+    AQLP    Y    P+     +   P 
Sbjct: 873 CRTIVPNAPATIPLLAVAPPGVAA---LSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPH 929

Query: 400 GPIGGMM--PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP--MVPP 455
             +  M   PPQP +P Q  + PP P                   +PP    PP  ++PP
Sbjct: 930 HTVQNMRATPPQPALPPQPTL-PPQP------------------VLPPQPTLPPQPVLPP 970

Query: 456 YQGGPPR---PPMGMRPP 470
               PP+   PP  M PP
Sbjct: 971 QPTRPPQPVLPPQPMLPP 988



 Score = 73.2 bits (178), Expect = 5e-13
 Identities = 94/378 (24%), Positives = 127/378 (33%), Gaps = 77/378 (20%)

Query: 136  QGYIPPMAQPGLPPVP---GAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMM 192
            +G + P + P L        APG+P G  P     P L    P       P + P    M
Sbjct: 658  EGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPM 717

Query: 193  PPGPGIPPLMPGMPPGMPPPVPRPGI-----------------PPMTQAQAVSAPGIL-- 233
            P GPG P      PP +  P P P +                 P +  A  V AP  L  
Sbjct: 718  PTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKP 777

Query: 234  ----NRPPAPTATVPAPQP--PVTKPLFPSAGQMGTPVTSSSTASSN------------- 274
                  P  P A VP   P  PV  P+ P AG  G P       ++              
Sbjct: 778  LQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPA 837

Query: 275  --SESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKP-TFPAYTQSTAS 331
                SL+A      P+       +  P G    PL + P  T  P  P T P    +   
Sbjct: 838  VILPSLAAPLPPASPALPLQAVKLPHPPGA---PL-AMPCRTIVPNAPATIPLLAVAPPG 893

Query: 332  TTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQ 391
              + +  +A          PA     + T   + P    +++  RA  P+       P Q
Sbjct: 894  VAALSIHSAVAQLPGQPVYPAAFPQMAPTD--VPPSPHHTVQNMRATPPQ----PALPPQ 947

Query: 392  APIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 451
              +   PV P    +PPQP +P Q   RPP P                   +PP     P
Sbjct: 948  PTLPPQPVLPPQPTLPPQPVLPPQP-TRPPQP------------------VLPP----QP 984

Query: 452  MVPPYQGGPPRPPMGMRP 469
            M+PP    PP+P + +RP
Sbjct: 985  MLPPQPVLPPQPALPVRP 1002



 Score = 69.3 bits (168), Expect = 7e-12
 Identities = 56/179 (31%), Positives = 78/179 (43%), Gaps = 20/179 (11%)

Query: 123  ASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMP 182
            A T   P P    Q       QP LPP P  P  P  + P  P +PP  P +PP     P
Sbjct: 920  APTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP--VLPPQPTLPP-QPVLPPQPTRPP 976

Query: 183  PGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTA- 241
              ++P   M+PP P +PP  P +P  + P   +P +P      A     IL   PAP A 
Sbjct: 977  QPVLPPQPMLPPQPVLPP-QPALP--VRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAV 1033

Query: 242  -------TVPAP-----QPPVTKPLFPSAGQMGTPVTSS-STASSNSESLSASSKALFP 287
                   TVP P      PP+ + L P+A ++     SS +T S++ +S+   +  L P
Sbjct: 1034 DVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 110/471 (23%), Positives = 143/471 (30%), Gaps = 106/471 (22%)

Query: 85  IPEKDMDERRRLLEQKTQESQKKKQQDDSDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQ 144
           I  K + +R  L++ + +      Q  +  +    D A      P P+Q Q  Y     Q
Sbjct: 527 IVAKSIRDRVALIQWRRERIWPALQPKEQQDVGSPDKARGP---PVPLQVQVTYHAQAGQ 583

Query: 145 PGLPPVPGAPG-----MPPGI--------------------------------------- 160
           PG PP P  P      +PP +                                       
Sbjct: 584 PG-PPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLAD 642

Query: 161 -----------PPLMPG--VPPLMPGM-----PPVMPGMPPGMMPMGGMMPP-------- 194
                      PP+  G  +P  +P +     P   PG+P G +P     P         
Sbjct: 643 AAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDP 702

Query: 195 ----GPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP-APQPP 249
                P +PP    MP G   P P PG  P   AQ    P +L    AP   VP  P PP
Sbjct: 703 AMSFAPVLPPPSTPMPTGPGQPAP-PGQQPPPLAQPTPLPQVL----APQPVVPLQPVPP 757

Query: 250 VTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNS 309
              P    A Q+G P             L        P    AQ   Q P      P+  
Sbjct: 758 HLPPYLAPASQVGAPA-----------QLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITP 806

Query: 310 TPATTTEPPK-PTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDE 368
                  PP  P  P  T          +     P+ +    PA+        KL HP  
Sbjct: 807 LAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPG 866

Query: 369 DISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQY 428
                  R  +P     +P    AP G   +  I   +   PG P      P M P    
Sbjct: 867 APLAMPCRTIVPNAPATIPLLAVAPPGVAALS-IHSAVAQLPGQPVYPAAFPQMAPTDVP 925

Query: 429 GGHH---QGMPGYLP-GAMPPYGQGP--PMVPPYQGGPPR---PPMGMRPP 470
              H   Q M    P  A+PP    P  P++PP    PP+   PP   RPP
Sbjct: 926 PSPHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP 976



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 76/282 (26%), Positives = 104/282 (36%), Gaps = 41/282 (14%)

Query: 216 PGIPPMTQAQAVSAPGILNRPPAP-----TATVPAPQPPVTKPLFPSAGQMGTPVT---S 267
           P + P  Q Q V +P     PP P     T    A QP   +P  P A Q   P T   S
Sbjct: 548 PALQPKEQ-QDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTS 606

Query: 268 SSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQ 327
           +++ +S+S   S     ++  +  +Q +V      D  P  S       PP    P   Q
Sbjct: 607 ATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP--SPAQCVCSPPVSEGPVLPQ 664

Query: 328 STASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDIS--LEERRAQLPKYQRN 385
           S  S  +    TAA P   + S PA     S       P    +  L      +P     
Sbjct: 665 SLPSLGAYQQPTAA-PGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQ 723

Query: 386 LPRPGQAPIGNPPVG---PIGGMMPPQPGIPQQQGMRPPMPPH--------GQYGGHHQG 434
              PGQ P   PP+    P+  ++ PQP +P Q     P+PPH         Q G   Q 
Sbjct: 724 PAPPGQQP---PPLAQPTPLPQVLAPQPVVPLQ-----PVPPHLPPYLAPASQVGAPAQL 775

Query: 435 MPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQGG 476
            P  +P A        P+ P  Q  P  PP+ + PP+    G
Sbjct: 776 KPLQMPQA--------PLQPLAQVPPQMPPIPVVPPITPLAG 809



 Score = 52.4 bits (124), Expect = 9e-07
 Identities = 62/237 (26%), Positives = 85/237 (35%), Gaps = 49/237 (20%)

Query: 141  PMAQPGLPPVPGAPGMPPGIPPLMPGVPPL--------MPGMPPVMPGMPPGMMPMG--- 189
            P+A P    VP AP   P +    PGV  L        +PG P V P   P M P     
Sbjct: 868  PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQP-VYPAAFPQMAPTDVPP 926

Query: 190  ---------GMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPM----TQAQAVSAPGILNRP 236
                        PP P +PP  P +PP  P   P+P +PP      Q      P +  +P
Sbjct: 927  SPHHTVQNMRATPPQPALPP-QPTLPP-QPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQP 984

Query: 237  PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAV 296
              P   V  PQP +  P+ P   Q   P  ++  A+  S+ L        P+      A 
Sbjct: 985  MLPPQPVLPPQPAL--PVRPEPLQPHLPEQAAPAATPGSQILLG-----HPAPYAVDVAA 1037

Query: 297  QGPVGTDFKPLNSTPATTTEPPKP---------TFPAYTQSTASTTSTTNSTAAKPA 344
            Q P       +   PA    PP P           P +  S A+ +++  S   + A
Sbjct: 1038 QVPT------VPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTA 1088



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 70/288 (24%), Positives = 95/288 (32%), Gaps = 56/288 (19%)

Query: 112  DSDEYDDDDSAASTSFQPQPVQPQQ--GYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPP 169
            DS  Y D     S+  QP  +  QQ      P   PG PP P AP  PP       G  P
Sbjct: 1345 DSAPYKDQ---LSSKEQPSFLASQQLLSQAGPSNPPGAPPAPLAPSSPPVTALPQDGAAP 1401

Query: 170  LMPGMPPVM---------PGMPPGM-------MPMGGMMPPGPGIPPLMPGMPPGMPPPV 213
                MP            PG P G+        P+         + PL+ G+ P  P   
Sbjct: 1402 ATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTP--- 1458

Query: 214  PRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASS 273
                 P     +  SAP    R P P    PAP+P       P +G      T       
Sbjct: 1459 ----APEAASTRDASAP----REPLPP---PAPEPS------PHSG------TPQPALGQ 1495

Query: 274  NSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTT 333
             +  L A+  A+  +T+Q  +   GP      P          PP+  F           
Sbjct: 1496 PAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGF---------VD 1546

Query: 334  STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPK 381
            ST  S   K    +  +    ++ SA + +   D D +LE  R   P+
Sbjct: 1547 STIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPR 1594



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 56/234 (23%), Positives = 83/234 (35%), Gaps = 32/234 (13%)

Query: 239  PTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQ--AQAAV 296
            P A  PAP+ P + P  P +     P  +S  ++   + LS+  +  F ++ Q  +QA  
Sbjct: 1317 PVAEHPAPEAPESSPPLPLSS---LPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGP 1373

Query: 297  QGPVGTDFKPL--NSTPATT-----TEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS 349
              P G    PL  +S P T        P   T P     TAS      +     +   TS
Sbjct: 1374 SNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETS 1433

Query: 350  KPATLTTTSATSKLIHP---------DEDISLEERRAQLPKYQRNLPRPGQAP---IGNP 397
            +P  L  T      + P             +   R A  P+     P P  +P      P
Sbjct: 1434 QP--LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQP 1491

Query: 398  PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 451
             +G    ++P   G       + P PP G        +P   P A+   G+GPP
Sbjct: 1492 ALGQPAPLLPAAVGAVSLATSQLPSPPLG------PTVPPQPPSALESDGEGPP 1539



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 47/187 (25%), Positives = 69/187 (36%), Gaps = 21/187 (11%)

Query: 129  PQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMP--GVPPLMPGMPPVMPGMPPGMM 186
            PQP+ P Q        P LPP P  P  P  + P +P    P   PG   ++    P  +
Sbjct: 982  PQPMLPPQ--------PVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAV 1033

Query: 187  PMGGMMPPGPGIPP---LMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATV 243
             +   +P  P +PP   L P +P  + P  P   + P   +   +    +   P  TAT+
Sbjct: 1034 DVAAQVPTVP-VPPAAVLSPPLPEVLLPAAPE--LLPQFPSSLATVSASVQSVPTQTATL 1090

Query: 244  PAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTD 303
                PP   PL    G      T   T     E  ++  K   P   Q+  +  G   T 
Sbjct: 1091 ---LPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKP--PGLPQSCESYGGSDVTS 1145

Query: 304  FKPLNST 310
             K L+ +
Sbjct: 1146 GKELSDS 1152



 Score = 29.3 bits (64), Expect = 8.2
 Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 10/69 (14%)

Query: 185  MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP 244
            M    G   PG       P    GMP   P PG  P++      A        APT +VP
Sbjct: 2158 MEAQAGWAAPGEARAMTAPRAGVGMPRLPPAPG--PLSTTVIPGA--------APTLSVP 2207

Query: 245  APQPPVTKP 253
             P P   KP
Sbjct: 2208 TPDPESEKP 2216


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 67/197 (34%), Positives = 83/197 (42%), Gaps = 31/197 (15%)

Query: 129 PQPVQPQQGYIPPMAQPGL------PPV--PGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           P P  P Q   PP+A P        PPV  PG P   P + PL PG PP +PG  P  PG
Sbjct: 250 PGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPP-PG 308

Query: 181 MPP---GMMPMGGMMPP---GPGIPPL-------MPGMPPGMPPPVPRPG---IPPMTQA 224
            PP   G  P  G  PP   GP  PPL       +PG PPG PPP P       PP T +
Sbjct: 309 PPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368

Query: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMG---TPVTSSSTASSNSESLSAS 281
                P   +R P PT     P P       P   +M    TP++ +      + + + S
Sbjct: 369 ---GMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTARTPLSEAEFEEIMNRNRAIS 425

Query: 282 SKALFPSTAQAQAAVQG 298
           S A+  + + A A   G
Sbjct: 426 SSAISRAVSDASAGDYG 442



 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 56/158 (35%), Positives = 61/158 (38%), Gaps = 29/158 (18%)

Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMM--PMGGMMPPGP- 196
           P  A PG PP P   G  P  PPL P  PP  PG PP    +PP +   P  G  PP P 
Sbjct: 218 PGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPV 277

Query: 197 -------GIPPL---MPGMPPGMP-------PPVPRPGIPPMTQAQAVSAPGILNRP--- 236
                  G PPL    PG PP +P       PP P+ G PP         PG L  P   
Sbjct: 278 LFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTL 337

Query: 237 ------PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSS 268
                 P P    P P P V    FP     G P + S
Sbjct: 338 APPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDS 375



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 42/101 (41%), Positives = 48/101 (47%), Gaps = 18/101 (17%)

Query: 387 PRPGQAPIGNP-PVGPI--GGMMPPQPGIPQQQGMRPPMP------PHGQ--YGGHHQGM 435
           PRP   P G P P GP   G ++PP    P  +G RPP P      P GQ   G    G 
Sbjct: 237 PRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGP 296

Query: 436 PGYLPGAMPPYG-----QGPPMVPPYQGGPPRPPMGMRPPV 471
           P  +PG  PP G     QGPP  PP    PPRPP  + PP+
Sbjct: 297 PPPVPGYGPPPGPPPPQQGPP--PPPGPFPPRPPGPLGPPL 335



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 36/87 (41%), Positives = 39/87 (44%), Gaps = 18/87 (20%)

Query: 389 PGQAPIGNPPVGPIG-GMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYG 447
           PGQ P G PP+GP+  G  PP PG        PP PP  Q G      P   PG  PP  
Sbjct: 280 PGQ-PFGQPPLGPLPPGPPPPVPGYGP-----PPGPPPPQQG------PPPPPGPFPPRP 327

Query: 448 QGPPMVPPYQGGP----PRPPMGMRPP 470
            G P+ PP    P    P PP G  PP
Sbjct: 328 PG-PLGPPLTLAPPPHLPGPPPGAPPP 353



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 38/101 (37%), Positives = 45/101 (44%), Gaps = 6/101 (5%)

Query: 376 RAQLPKYQRNLPR-PGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG 434
           RA  P+  R   R PG  P G+   GP G   PP P    Q   RPP+ P G  G     
Sbjct: 194 RAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPP 253

Query: 435 MPGYL---PGAMPP-YGQGPPMVPPYQGGP-PRPPMGMRPP 470
            PG +   P A PP  G  PP    + G P  +PP+G  PP
Sbjct: 254 PPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 35/100 (35%), Positives = 37/100 (37%), Gaps = 25/100 (25%)

Query: 387 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYG-----GHHQGMPGYLPG 441
           P PG  P   PP        PPQ G P   G  PP PP G  G          +PG  PG
Sbjct: 299 PVPGYGPPPGPP--------PPQQGPPPPPGPFPPRPP-GPLGPPLTLAPPPHLPGPPPG 349

Query: 442 AMPPYGQ-GPPMVPP----------YQGGPPRPPMGMRPP 470
           A PP     P   PP           +G PP  P G  PP
Sbjct: 350 APPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPP 389


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 100/376 (26%), Positives = 132/376 (35%), Gaps = 58/376 (15%)

Query: 117 DDDDSAASTSFQPQPVQPQQG-----YIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM 171
           D + S   T+ + + VQ +QG       PP+ Q    P+P   G  PG  PL        
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG--PGRDPLQ------Q 232

Query: 172 PGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPP---PVPRPGIPPMTQAQAVS 228
            G P  +    P  +      PPG G P   P   P       P+ R    P T+ QA  
Sbjct: 233 DGTPKSISSQQPEKIKS---QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADI 288

Query: 229 APGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
             G   +P  P+ + P  Q P   P  P A Q G   +    A        A    L   
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPT--PGKPPAQQPGHEKSQPGPAKP-----PAQPSGLTKP 341

Query: 289 TAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASIT 348
            AQ    V+ PV          P TT  P +P  PA  +  A  T +   ++ +P     
Sbjct: 342 LAQQPGTVKPPV--------QPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL 391

Query: 349 SKPATLTTTSATSK--LIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
           ++P  +  T A        P + +   +  AQ P  Q     PG  P   P   P  G +
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKI 449

Query: 407 PPQ---PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 463
           P Q   PG    Q   P  PP          +PG  P   PP   GP   PP Q G  +P
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPP--------SQLPG--PAKPPPQQPGPAKPPPQQPGSAKP 499

Query: 464 PM----GMRPPVMSQG 475
           P       +PP    G
Sbjct: 500 PSQQPGSTKPPPQQPG 515



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 79/314 (25%), Positives = 105/314 (33%), Gaps = 34/314 (10%)

Query: 133 QPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL-MPGV---PPLMPGM---PPVMPGM--PP 183
           QP  G IP  AQ   P    A    P  PP  +PG    PP  PG    PP  PG   PP
Sbjct: 443 QPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 184 GMMPMGGMMPPG-PGIPPLMPGMPPGMPPPVPRPG-IPPMTQAQAVSAPGILN--RPPAP 239
              P     PP  PG     P  P    PP  +PG   P  Q  + + P      +P + 
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560

Query: 240 TATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP 299
           T +    QPP   P        G P T     ++    L    KA F +  + Q  V   
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 300 VGTDFKP----------LNSTPATTTE---PPKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
            G +  P          LN            P P+ P     TA  T+T+  + + P   
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 347 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
            TS           SK   P +   L ++            +P +A   + P        
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA------P 734

Query: 407 PPQPGIPQQQGMRP 420
           P +P +P +Q   P
Sbjct: 735 PKEPSVPSEQDKAP 748



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 95/408 (23%), Positives = 125/408 (30%), Gaps = 86/408 (21%)

Query: 97  LEQKTQESQKKKQQDDSDEYDDDDSAAS-TSFQPQPVQPQQ-GYIPPMAQPGLPPVPGAP 154
           L+Q+  +   K+Q    D    D +  S +S QP+ ++ Q  G   P+  P   P     
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 155 GMP------------------PGIPPLMPGVPPLMPGMPPVM---PGMPPGMMPMGGMMP 193
            +P                    + P +P      P  PP+    PG PP   P      
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPS-----PSKPPIQQPTPGKPPAQQPGHEKSQ 325

Query: 194 PGPGIPPLMPG-----------------MPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
           PGP  PP  P                   PPG   P  +P  P    AQ   +    +  
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385

Query: 237 PAPTA--------TVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
           P P A          PA QP    P  P   Q+GTP        +    L + +KA  P+
Sbjct: 386 PGPKALAQPPGVGKTPAQQP---GPAKPPTQQVGTP-----KPLAQQPGLQSPAKAPGPT 437

Query: 289 TAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASI- 347
               Q    G +         T A  T P KP  P+     A         A  P     
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP--PSQLPGPAKPPPQQPGPAKPPPQQPG 495

Query: 348 TSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMP 407
           ++KP              P +     +   Q P   +  P P Q     PP    G   P
Sbjct: 496 SAKP--------------PSQQPGSTKPPPQQPGPAK--PSPQQPGSTKPPSQQPGSAKP 539

Query: 408 ----PQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 451
               P P  P  Q    P+   G   G     P   P A  P  QG P
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG--SGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 21/243 (8%)

Query: 122  AASTSFQPQPVQPQQGY----IPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPV 177
            + S S    P +P+  +    +   AQP  PP P  P  PP  PP  P +PP     P +
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437

Query: 178  MPGMPPGM-MPMGGMMPPGPGIPPL-------MPGMPPGMPPPVPRPGIPPMTQAQAVSA 229
            +P     +  P+    P    +  L         G+P         P +PP  +  ++ +
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP--KPSSIPS 2495

Query: 230  PGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPV----TSSSTASSNSESLSASSKAL 285
              +    P P+    AP+P +  P  P+  Q  T +    T  S  SS + +L  S+   
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVI--PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553

Query: 286  FPSTAQAQAAVQGPVGTDF-KPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             PS     +         F K L  T    T P +P  P  + ++ + TS    + +K  
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDL 2613

Query: 345  ASI 347
             S+
Sbjct: 2614 VSV 2616



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 52/331 (15%)

Query: 180 GMPPGMMPMGGMMPPG----PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAV----SAPG 231
           G+P G +P      P       +    P    G PP   RP  P +++++      S   
Sbjct: 65  GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 232 ILNRPPAPTATVPAPQPPVTKPLFPSAGQMG--TPVTSSSTASS-----NSESLSASSKA 284
           +  R P+  +   +      K    S+   G  + V + S  SS     N   L + S+A
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNST-PATTTEPPKPT--------FPAYTQSTASTTST 335
               T + Q  VQ   G   KP     P    +PPKP          P     T  + S+
Sbjct: 185 SQEETTKKQKVVQKEQG---KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS 241

Query: 336 TNSTAAKPAASITSKPA---TLTTTSATSKLIHPDEDISLEERRAQLPKYQR---NLPRP 389
                 K     T KP    T T  +  +KL    +    + ++A + + +    +LP P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 390 GQAPIGNPPVGPIGGMMPP--QPGIPQQQG--MRPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            + PI  P  G      PP  QPG  + Q    +PP  P G             P A  P
Sbjct: 302 SKPPIQQPTPGK-----PPAQQPGHEKSQPGPAKPPAQPSGLTK----------PLAQQP 346

Query: 446 YGQGPPMVPPYQGGPPRPPMGMRPPVMSQGG 476
               PP+ PP    PP  P+G   P   Q G
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 82/347 (23%), Positives = 116/347 (33%), Gaps = 98/347 (28%)

Query: 212 PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP------------APQPPVTKPLFPSAG 259
           PVP    P +  A   +   +    P P  T P            AP+P    PL     
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 260 QMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTD-------FKP---LNS 309
             G+P ++ +     ++SLS  +    PS    Q   + PV  D        KP   L S
Sbjct: 712 LHGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQD--KAPVADDKPKQPKMVKPTTDLVS 768

Query: 310 TPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS--------KPATLTTTSATS 361
           + + TT+P  P+    +Q+   TT    + +AKP+ S               +   ++ S
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828

Query: 362 KLI-HPDEDISLEERRAQLPKYQRNLPRPGQA-----------PIGNP-PVG--PIGGMM 406
           K+I HP      + ++   P  ++  P+  Q            P G+P P G  P  G  
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888

Query: 407 PPQP---GIPQQQGMR--------------PPMPPH------------------------ 425
            P P     PQ+Q  R               P  P                         
Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948

Query: 426 -GQYGGHHQGMPGYLPGAMPPYGQGP-PMVPPYQGGPPRPPMGMRPP 470
            GQ G H Q  PG       P  Q P P  PP   GPP+   G  PP
Sbjct: 949 AGQPGPHSQSGPG------APMKQAPAPSQPPTSQGPPK-STGQAPP 988



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 66/259 (25%), Positives = 88/259 (33%), Gaps = 43/259 (16%)

Query: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 284
           + +  P +  +PP P   +P  Q P   PL     Q GTP    S +S   E + +    
Sbjct: 204 EGIIKPPLQQQPPKP---IPKQQGPGRDPL----QQDGTP---KSISSQQPEKIKSQP-- 251

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             P T +    +QGP  T           T     P     ++            + KP+
Sbjct: 252 --PGTGKP---IQGPTQTP---------QTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGN--PPVGPI 402
               SKP     T        P  + S +   A+ P     L +P     G   PPV P 
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 403 GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG--MPGYLPGAMPPYGQGPPMVPPYQGGP 460
           G   PP       Q + P  PP  Q G        PG    A PP   G    P  Q GP
Sbjct: 357 GTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGP 407

Query: 461 PRPP---MGMRPPVMSQGG 476
            +PP   +G   P+  Q G
Sbjct: 408 AKPPTQQVGTPKPLAQQPG 426



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 57/238 (23%), Positives = 86/238 (36%), Gaps = 38/238 (15%)

Query: 153  APGMPPGIPPL--MPGVP-PLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGM 209
            A  +P G P +  +P  P P        +   PP   P     PP P  PP     PP +
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP-----PPPL 2427

Query: 210  PPPV-PRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSS 268
            PPP  P+P I P  +    S        P  TAT          PLF +     T + ++
Sbjct: 2428 PPPTSPKPTILPKKKLTVAS--------PVTTAT----------PLFDAV----TTLETT 2465

Query: 269  STASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQS 328
            +   SN   ++       P      +++   +    +P  S P    +P  P  P  TQ 
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ- 2524

Query: 329  TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL 386
                   T+        S+TS       TSA  KL  P   +S    ++  P++ ++L
Sbjct: 2525 -----KPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSS-PRFSKSL 2576



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 75/322 (23%), Positives = 117/322 (36%), Gaps = 59/322 (18%)

Query: 120  DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIP--------------PLMP 165
            D +A     P P  P     PP   P LPP P +P  P  +P              PL  
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPP-PTSP-KPTILPKKKLTVASPVTTATPLFD 2457

Query: 166  GVPPL-------MPGMP--PVMPGMPPGMMPMGGMMP--------PGPGIPPLMP-GMPP 207
             V  L         G+P   +    PP + P    +P        P P  PP+ P  + P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP 2517

Query: 208  GMPPPVPRP-GIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPV------TKPLFPSA-- 258
             +P    +P  I P     ++++   LN   +    +P+P  P+      + P F  +  
Sbjct: 2518 QLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577

Query: 259  ---------GQMGTPVTSSSTASSNSESLSASSKALFP-----STAQAQAAVQGPVGTDF 304
                      + GTP  SS++ +  S  L + SK L       S      AV+ P+ ++ 
Sbjct: 2578 ETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637

Query: 305  KPLNSTPATTTEPPKPTFPAYTQST-ASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 363
                S    T      T P+  Q+   S T    +  +K   S T   A     S+ S  
Sbjct: 2638 TFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISIT 2697

Query: 364  IHPDEDISLEERRAQLPKYQRN 385
            I P E ++L+    + P+Y+ +
Sbjct: 2698 I-PPEPLALDNIHLEKPQYKED 2718



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 55/237 (23%), Positives = 77/237 (32%), Gaps = 52/237 (21%)

Query: 128  QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMP 187
            Q  PVQ ++   P  AQ  + P P A  MP G P                    PPG  P
Sbjct: 845  QVDPVQKKEE--PKKAQTKMSPKPDAKPMPKGSP-------------------TPPGPRP 883

Query: 188  MGGMMPPGPGIPPLMPGM-------------PPGMPPPVPRP---------GIPPMTQAQ 225
              G   P P   P                   P   P  P+          G    +QA 
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS 943

Query: 226  AV------SAPGILNRPPAPTATVPAP-QPPVTKPLFPSAGQMGTPVTSSSTASSNSESL 278
             +        P   + P AP    PAP QPP ++    S GQ   P   + +     E+ 
Sbjct: 944  NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVKKETK 1001

Query: 279  SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTST 335
            + +++ L P   QA    +        P+  + + T EP K   P   + +    ST
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 78/339 (23%), Positives = 111/339 (32%), Gaps = 64/339 (18%)

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           + + +S QPQ   P++   P       P        P   PPL+    P + G P     
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPE-------PKKPPPLVK--QPTLHGSPSAKAK 721

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQ--AQAVSAPGILNRPPA 238
            PP       +  P P   P +P      P    +P  P M +     VS+     +P  
Sbjct: 722 QPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778

Query: 239 PTATVPAPQPPVTKP-----------LFPSAGQMGTPVTSSSTASSNSESLSASSKALFP 287
           P++ V +     T P            FP  G+  +P  S +     S+S   S     P
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG--P 836

Query: 288 STAQAQAAVQGPVGTDFKPLNSTPATTTEP-----PK--PTFPAYTQSTASTTSTTNSTA 340
           S+         PV    +P  +    + +P     PK  PT P   + TA  T  T   +
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQS 895

Query: 341 AKPA----------ASITSKPATLTTTSATSKLIHPDEDIS--LEERRAQLPKYQRNLPR 388
            KP            SIT  P +  TT        P E ++  L    A +     NL  
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTT--------PQETVTGKLFGFGASIFSQASNLIS 947

Query: 389 PGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 427
               P  +   GP         G P +Q   P  PP  Q
Sbjct: 948 TAGQPGPHSQSGP---------GAPMKQAPAPSQPPTSQ 977



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 55/233 (23%), Positives = 78/233 (33%), Gaps = 18/233 (7%)

Query: 141  PMAQPGLPPVPGAP-----GMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPG 195
            P   P +  +P  P          I    P  PP  P  PP  P  PP  +P     PP 
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP-----PPT 2431

Query: 196  PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 255
               P ++P     +  PV     P       +    +L     P   +    PP   P  
Sbjct: 2432 SPKPTILPKKKLTVASPV-TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK- 2489

Query: 256  PSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ-GPVG---TDFKPLNSTP 311
            PS+   G   T     S    +       L P+T Q    +   P G   T    LN   
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 312  ATTTEPPKPTFPAYTQSTASTTSTTNS-TAAKPAASITSKPATLTTTSATSKL 363
            +   + P PT P    S  S+   + S T      ++ S+P T T +SA+  +
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 5/62 (8%)

Query: 60   ETIDAVPNAIPGRTDIELEIYGMEG----IPEKDMDERRRLLEQKTQESQKKKQQDDSDE 115
            ETID+VP  +   +++  E+ G E     +PE+D  +++  LE++  E +K KQQ  ++E
Sbjct: 3176 ETIDSVPT-LTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE 3234

Query: 116  YD 117
             +
Sbjct: 3235 LE 3236


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 100/376 (26%), Positives = 132/376 (35%), Gaps = 58/376 (15%)

Query: 117 DDDDSAASTSFQPQPVQPQQG-----YIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLM 171
           D + S   T+ + + VQ +QG       PP+ Q    P+P   G  PG  PL        
Sbjct: 181 DSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQG--PGRDPLQ------Q 232

Query: 172 PGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGMPP---PVPRPGIPPMTQAQAVS 228
            G P  +    P  +      PPG G P   P   P       P+ R    P T+ QA  
Sbjct: 233 DGTPKSISSQQPEKIKS---QPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTK-QADI 288

Query: 229 APGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
             G   +P  P+ + P  Q P   P  P A Q G   +    A        A    L   
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPT--PGKPPAQQPGHEKSQPGPAKP-----PAQPSGLTKP 341

Query: 289 TAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASIT 348
            AQ    V+ PV          P TT  P +P  PA  +  A  T +   ++ +P     
Sbjct: 342 LAQQPGTVKPPV--------QPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL 391

Query: 349 SKPATLTTTSATSK--LIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
           ++P  +  T A        P + +   +  AQ P  Q     PG  P   P   P  G +
Sbjct: 392 AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG--PTKTPVQQPGPGKI 449

Query: 407 PPQ---PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRP 463
           P Q   PG    Q   P  PP          +PG  P   PP   GP   PP Q G  +P
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPP--------SQLPG--PAKPPPQQPGPAKPPPQQPGSAKP 499

Query: 464 PM----GMRPPVMSQG 475
           P       +PP    G
Sbjct: 500 PSQQPGSTKPPPQQPG 515



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 79/314 (25%), Positives = 105/314 (33%), Gaps = 34/314 (10%)

Query: 133 QPQQGYIPPMAQPGLPPVPGAPGMPPGIPPL-MPGV---PPLMPGM---PPVMPGM--PP 183
           QP  G IP  AQ   P    A    P  PP  +PG    PP  PG    PP  PG   PP
Sbjct: 443 QPGPGKIP--AQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPP 500

Query: 184 GMMPMGGMMPPG-PGIPPLMPGMPPGMPPPVPRPG-IPPMTQAQAVSAPGILN--RPPAP 239
              P     PP  PG     P  P    PP  +PG   P  Q  + + P      +P + 
Sbjct: 501 SQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ 560

Query: 240 TATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGP 299
           T +    QPP   P        G P T     ++    L    KA F +  + Q  V   
Sbjct: 561 TGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSL 620

Query: 300 VGTDFKP----------LNSTPATTTE---PPKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
            G +  P          LN            P P+ P     TA  T+T+  + + P   
Sbjct: 621 CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQ 680

Query: 347 ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMM 406
            TS           SK   P +   L ++            +P +A   + P        
Sbjct: 681 QTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA------P 734

Query: 407 PPQPGIPQQQGMRP 420
           P +P +P +Q   P
Sbjct: 735 PKEPSVPSEQDKAP 748



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 95/408 (23%), Positives = 125/408 (30%), Gaps = 86/408 (21%)

Query: 97  LEQKTQESQKKKQQDDSDEYDDDDSAAS-TSFQPQPVQPQQ-GYIPPMAQPGLPPVPGAP 154
           L+Q+  +   K+Q    D    D +  S +S QP+ ++ Q  G   P+  P   P     
Sbjct: 211 LQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270

Query: 155 GMP------------------PGIPPLMPGVPPLMPGMPPVM---PGMPPGMMPMGGMMP 193
            +P                    + P +P      P  PP+    PG PP   P      
Sbjct: 271 KLPLQRDASRPQTKQADIVRGESVKPSLPS-----PSKPPIQQPTPGKPPAQQPGHEKSQ 325

Query: 194 PGPGIPPLMPG-----------------MPPGMPPPVPRPGIPPMTQAQAVSAPGILNRP 236
           PGP  PP  P                   PPG   P  +P  P    AQ   +    +  
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385

Query: 237 PAPTA--------TVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPS 288
           P P A          PA QP    P  P   Q+GTP        +    L + +KA  P+
Sbjct: 386 PGPKALAQPPGVGKTPAQQP---GPAKPPTQQVGTP-----KPLAQQPGLQSPAKAPGPT 437

Query: 289 TAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASI- 347
               Q    G +         T A  T P KP  P+     A         A  P     
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP--PSQLPGPAKPPPQQPGPAKPPPQQPG 495

Query: 348 TSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPVGPIGGMMP 407
           ++KP              P +     +   Q P   +  P P Q     PP    G   P
Sbjct: 496 SAKP--------------PSQQPGSTKPPPQQPGPAK--PSPQQPGSTKPPSQQPGSAKP 539

Query: 408 ----PQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPP 451
               P P  P  Q    P+   G   G     P   P A  P  QG P
Sbjct: 540 SAQQPSPAKPSAQQSTKPVSQTG--SGKPLQPPTVSPSAKQPPSQGLP 585



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 57/243 (23%), Positives = 92/243 (37%), Gaps = 21/243 (8%)

Query: 122  AASTSFQPQPVQPQQGY----IPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPV 177
            + S S    P +P+  +    +   AQP  PP P  P  PP  PP  P +PP     P +
Sbjct: 2378 SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTI 2437

Query: 178  MPGMPPGM-MPMGGMMPPGPGIPPL-------MPGMPPGMPPPVPRPGIPPMTQAQAVSA 229
            +P     +  P+    P    +  L         G+P         P +PP  +  ++ +
Sbjct: 2438 LPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP--KPSSIPS 2495

Query: 230  PGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPV----TSSSTASSNSESLSASSKAL 285
              +    P P+    AP+P +  P  P+  Q  T +    T  S  SS + +L  S+   
Sbjct: 2496 GLVFTHRPEPSKPPIAPKPVI--PQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYK 2553

Query: 286  FPSTAQAQAAVQGPVGTDF-KPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             PS     +         F K L  T    T P +P  P  + ++ + TS    + +K  
Sbjct: 2554 LPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDL 2613

Query: 345  ASI 347
             S+
Sbjct: 2614 VSV 2616



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 81/331 (24%), Positives = 117/331 (35%), Gaps = 52/331 (15%)

Query: 180 GMPPGMMPMGGMMPPG----PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAV----SAPG 231
           G+P G +P      P       +    P    G PP   RP  P +++++      S   
Sbjct: 65  GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124

Query: 232 ILNRPPAPTATVPAPQPPVTKPLFPSAGQMG--TPVTSSSTASS-----NSESLSASSKA 284
           +  R P+  +   +      K    S+   G  + V + S  SS     N   L + S+A
Sbjct: 125 LPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA 184

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNST-PATTTEPPKPT--------FPAYTQSTASTTST 335
               T + Q  VQ   G   KP     P    +PPKP          P     T  + S+
Sbjct: 185 SQEETTKKQKVVQKEQG---KPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISS 241

Query: 336 TNSTAAKPAASITSKPA---TLTTTSATSKLIHPDEDISLEERRAQLPKYQR---NLPRP 389
                 K     T KP    T T  +  +KL    +    + ++A + + +    +LP P
Sbjct: 242 QQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSP 301

Query: 390 GQAPIGNPPVGPIGGMMPP--QPGIPQQQG--MRPPMPPHGQYGGHHQGMPGYLPGAMPP 445
            + PI  P  G      PP  QPG  + Q    +PP  P G             P A  P
Sbjct: 302 SKPPIQQPTPGK-----PPAQQPGHEKSQPGPAKPPAQPSGLTK----------PLAQQP 346

Query: 446 YGQGPPMVPPYQGGPPRPPMGMRPPVMSQGG 476
               PP+ PP    PP  P+G   P   Q G
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 82/347 (23%), Positives = 116/347 (33%), Gaps = 98/347 (28%)

Query: 212 PVPRPGIPPMTQAQAVSAPGILNRPPAPTATVP------------APQPPVTKPLFPSAG 259
           PVP    P +  A   +   +    P P  T P            AP+P    PL     
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711

Query: 260 QMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTD-------FKP---LNS 309
             G+P ++ +     ++SLS  +    PS    Q   + PV  D        KP   L S
Sbjct: 712 LHGSP-SAKAKQPPEADSLSKPAPPKEPSVPSEQD--KAPVADDKPKQPKMVKPTTDLVS 768

Query: 310 TPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAASITS--------KPATLTTTSATS 361
           + + TT+P  P+    +Q+   TT    + +AKP+ S               +   ++ S
Sbjct: 769 SSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDS 828

Query: 362 KLI-HPDEDISLEERRAQLPKYQRNLPRPGQA-----------PIGNP-PVG--PIGGMM 406
           K+I HP      + ++   P  ++  P+  Q            P G+P P G  P  G  
Sbjct: 829 KIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQT 888

Query: 407 PPQP---GIPQQQGMR--------------PPMPPH------------------------ 425
            P P     PQ+Q  R               P  P                         
Sbjct: 889 VPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST 948

Query: 426 -GQYGGHHQGMPGYLPGAMPPYGQGP-PMVPPYQGGPPRPPMGMRPP 470
            GQ G H Q  PG       P  Q P P  PP   GPP+   G  PP
Sbjct: 949 AGQPGPHSQSGPG------APMKQAPAPSQPPTSQGPPK-STGQAPP 988



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 66/259 (25%), Positives = 88/259 (33%), Gaps = 43/259 (16%)

Query: 225 QAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKA 284
           + +  P +  +PP P   +P  Q P   PL     Q GTP    S +S   E + +    
Sbjct: 204 EGIIKPPLQQQPPKP---IPKQQGPGRDPL----QQDGTP---KSISSQQPEKIKSQP-- 251

Query: 285 LFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPA 344
             P T +    +QGP  T           T     P     ++            + KP+
Sbjct: 252 --PGTGKP---IQGPTQTP---------QTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 345 ASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGN--PPVGPI 402
               SKP     T        P  + S +   A+ P     L +P     G   PPV P 
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKS-QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPP 356

Query: 403 GGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQG--MPGYLPGAMPPYGQGPPMVPPYQGGP 460
           G   PP       Q + P  PP  Q G        PG    A PP   G    P  Q GP
Sbjct: 357 GTTKPPA------QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP---GVGKTPAQQPGP 407

Query: 461 PRPP---MGMRPPVMSQGG 476
            +PP   +G   P+  Q G
Sbjct: 408 AKPPTQQVGTPKPLAQQPG 426



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 57/238 (23%), Positives = 86/238 (36%), Gaps = 38/238 (15%)

Query: 153  APGMPPGIPPL--MPGVP-PLMPGMPPVMPGMPPGMMPMGGMMPPGPGIPPLMPGMPPGM 209
            A  +P G P +  +P  P P        +   PP   P     PP P  PP     PP +
Sbjct: 2373 ASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP-----PPPL 2427

Query: 210  PPPV-PRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSS 268
            PPP  P+P I P  +    S        P  TAT          PLF +     T + ++
Sbjct: 2428 PPPTSPKPTILPKKKLTVAS--------PVTTAT----------PLFDAV----TTLETT 2465

Query: 269  STASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQS 328
            +   SN   ++       P      +++   +    +P  S P    +P  P  P  TQ 
Sbjct: 2466 AVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ- 2524

Query: 329  TASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNL 386
                   T+        S+TS       TSA  KL  P   +S    ++  P++ ++L
Sbjct: 2525 -----KPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSS-PRFSKSL 2576



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 75/322 (23%), Positives = 117/322 (36%), Gaps = 59/322 (18%)

Query: 120  DSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIP--------------PLMP 165
            D +A     P P  P     PP   P LPP P +P  P  +P              PL  
Sbjct: 2400 DISAQPPPPPPPPPPPPPPPPPPPPPPLPP-PTSP-KPTILPKKKLTVASPVTTATPLFD 2457

Query: 166  GVPPL-------MPGMP--PVMPGMPPGMMPMGGMMP--------PGPGIPPLMP-GMPP 207
             V  L         G+P   +    PP + P    +P        P P  PP+ P  + P
Sbjct: 2458 AVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP 2517

Query: 208  GMPPPVPRP-GIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPV------TKPLFPSA-- 258
             +P    +P  I P     ++++   LN   +    +P+P  P+      + P F  +  
Sbjct: 2518 QLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577

Query: 259  ---------GQMGTPVTSSSTASSNSESLSASSKALFP-----STAQAQAAVQGPVGTDF 304
                      + GTP  SS++ +  S  L + SK L       S      AV+ P+ ++ 
Sbjct: 2578 ETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQ 2637

Query: 305  KPLNSTPATTTEPPKPTFPAYTQST-ASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 363
                S    T      T P+  Q+   S T    +  +K   S T   A     S+ S  
Sbjct: 2638 TFYISGALQTFSATPVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISIT 2697

Query: 364  IHPDEDISLEERRAQLPKYQRN 385
            I P E ++L+    + P+Y+ +
Sbjct: 2698 I-PPEPLALDNIHLEKPQYKED 2718



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 55/237 (23%), Positives = 77/237 (32%), Gaps = 52/237 (21%)

Query: 128  QPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMP 187
            Q  PVQ ++   P  AQ  + P P A  MP G P                    PPG  P
Sbjct: 845  QVDPVQKKEE--PKKAQTKMSPKPDAKPMPKGSP-------------------TPPGPRP 883

Query: 188  MGGMMPPGPGIPPLMPGM-------------PPGMPPPVPRP---------GIPPMTQAQ 225
              G   P P   P                   P   P  P+          G    +QA 
Sbjct: 884  TAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQAS 943

Query: 226  AV------SAPGILNRPPAPTATVPAP-QPPVTKPLFPSAGQMGTPVTSSSTASSNSESL 278
             +        P   + P AP    PAP QPP ++    S GQ   P   + +     E+ 
Sbjct: 944  NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ--APPAPAKSIPVKKETK 1001

Query: 279  SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTST 335
            + +++ L P   QA    +        P+  + + T EP K   P   + +    ST
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPEST 1058



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 78/339 (23%), Positives = 111/339 (32%), Gaps = 64/339 (18%)

Query: 121 SAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPG 180
           + + +S QPQ   P++   P       P        P   PPL+    P + G P     
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPE-------PKKPPPLVK--QPTLHGSPSAKAK 721

Query: 181 MPPGMMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQ--AQAVSAPGILNRPPA 238
            PP       +  P P   P +P      P    +P  P M +     VS+     +P  
Sbjct: 722 QPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778

Query: 239 PTATVPAPQPPVTKP-----------LFPSAGQMGTPVTSSSTASSNSESLSASSKALFP 287
           P++ V +     T P            FP  G+  +P  S +     S+S   S     P
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG--P 836

Query: 288 STAQAQAAVQGPVGTDFKPLNSTPATTTEP-----PK--PTFPAYTQSTASTTSTTNSTA 340
           S+         PV    +P  +    + +P     PK  PT P   + TA  T  T   +
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPG-PRPTAGQTVPTPQQS 895

Query: 341 AKPA----------ASITSKPATLTTTSATSKLIHPDEDIS--LEERRAQLPKYQRNLPR 388
            KP            SIT  P +  TT        P E ++  L    A +     NL  
Sbjct: 896 PKPQEQSRRFSLNLGSITDAPKSQPTT--------PQETVTGKLFGFGASIFSQASNLIS 947

Query: 389 PGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQ 427
               P  +   GP         G P +Q   P  PP  Q
Sbjct: 948 TAGQPGPHSQSGP---------GAPMKQAPAPSQPPTSQ 977



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 55/233 (23%), Positives = 78/233 (33%), Gaps = 18/233 (7%)

Query: 141  PMAQPGLPPVPGAP-----GMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPG 195
            P   P +  +P  P          I    P  PP  P  PP  P  PP  +P     PP 
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP-----PPT 2431

Query: 196  PGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLF 255
               P ++P     +  PV     P       +    +L     P   +    PP   P  
Sbjct: 2432 SPKPTILPKKKLTVASPV-TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK- 2489

Query: 256  PSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQ-GPVG---TDFKPLNSTP 311
            PS+   G   T     S    +       L P+T Q    +   P G   T    LN   
Sbjct: 2490 PSSIPSGLVFTHRPEPSKPPIAPKPVIPQL-PTTTQKPTDIHPKPTGLSLTSSMTLNLVT 2548

Query: 312  ATTTEPPKPTFPAYTQSTASTTSTTNS-TAAKPAASITSKPATLTTTSATSKL 363
            +   + P PT P    S  S+   + S T      ++ S+P T T +SA+  +
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAI 2601



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 20/62 (32%), Positives = 37/62 (59%), Gaps = 5/62 (8%)

Query: 60   ETIDAVPNAIPGRTDIELEIYGMEG----IPEKDMDERRRLLEQKTQESQKKKQQDDSDE 115
            ETID+VP  +   +++  E+ G E     +PE+D  +++  LE++  E +K KQQ  ++E
Sbjct: 3176 ETIDSVPT-LTTASEVFPEVVGDESALLIVPEEDKQQQQLDLERELLELEKIKQQRFAEE 3234

Query: 116  YD 117
             +
Sbjct: 3235 LE 3236


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 101/398 (25%), Positives = 134/398 (33%), Gaps = 100/398 (25%)

Query: 146 GLPPVPGAPGMPPGIPPLM--------PGVPP-----LMPG---MPPVMPG---MPPGMM 186
           G PP P A   PP  PPL         P +PP       PG    PPV      +P  + 
Sbjct: 243 GSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLG 302

Query: 187 PMGGMMP-PGPGIPPLMPG---------MPPGMPPPVPRPGIPPMTQAQAVSAPGILN-- 234
           P+GG     GPG PP +             P +PPP    G  P  QA + S    L   
Sbjct: 303 PLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPS 362

Query: 235 -----RPPA-----------------PTATVPAPQP----PVTKPLFPSA-GQMGTPVTS 267
                RPP                  P A  P PQP      ++P+ PS    +G P   
Sbjct: 363 QRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG 422

Query: 268 SSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQ 327
            S +  +   L + +    P T  + +                      PP+P  P    
Sbjct: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGS----------------------PPQPRHPIQPS 460

Query: 328 STASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRA-QLPKYQRNL 386
              +T+ + +S    PA    SK   + +    S    P E + +    A  LP      
Sbjct: 461 LPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS----PSEGLGMGAGPACPLPPLAGGE 516

Query: 387 PRPGQAPIGNPPVGPIG--GMMPPQPGIPQQQGMRPPMP--PHGQYG--GHHQGMPGYLP 440
             P  +P     +   G  GM+   P +P   G  PP P   H  +G      G P   P
Sbjct: 517 AFPFPSPEQGLALSGAGFPGMLGALP-LPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEP 575

Query: 441 GAMPPYGQGPPMVPPYQGGP--------PRPPMGMRPP 470
              PP G GPP+ P    GP        P PP  + PP
Sbjct: 576 LLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPP 613



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 90/365 (24%), Positives = 121/365 (33%), Gaps = 56/365 (15%)

Query: 140 PPMAQPGLPPVPGAPGMPPGIPPLMPGVPPLMPGMPPVMPGMPPGMMPMGGMMPPGPGIP 199
           PP   P   P+ G PG  P  PP +    P + G   + P      +P GG   P   +P
Sbjct: 147 PPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSP-RFLP 205

Query: 200 PLMPGMPPGMPPPVPRPGIPPMTQAQAVSA---PGILNRPPAPTATVPAPQPPVTKPLFP 256
                 P   PPP      P      A+ +   P  L  PPAP A   +  PP   PLF 
Sbjct: 206 RGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHA---SSSPPSDPPLFH 262

Query: 257 SAGQMGTPVTSSST--------ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDF--KP 306
            +  +  P    S         AS    S +     L          V+GP    F    
Sbjct: 263 CSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASS 322

Query: 307 LNSTPATTTEPPKPTFPAYTQS---TASTTSTTNSTAAKPAASITSKPATLTTTSATSKL 363
           L S  A    PP P  P+  Q     A   S ++S++ +P+     +P T+         
Sbjct: 323 LLSAAAKAQHPPLPP-PSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRL------ 375

Query: 364 IHPDEDISLEERRAQLPKYQR-NLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPM 422
                   LE R  Q P+  R   P P   P   P         P  P +    G+  P 
Sbjct: 376 --------LEGRGPQTPRRSRPRAPAPVPQPFSLPEPS-----QPILPSVLSLLGLPTPG 422

Query: 423 PPHGQYGGHHQGMPGYLP------GAMPPYGQGP--PMVPPYQG-------GPPRPPMGM 467
           P H     +  G   +LP         PP  + P  P +P           G P PP   
Sbjct: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS 482

Query: 468 RPPVM 472
           + PV+
Sbjct: 483 KAPVV 487



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 106/434 (24%), Positives = 146/434 (33%), Gaps = 86/434 (19%)

Query: 113 SDEYDDDDSAASTSFQPQPVQPQQGYIPPMAQPGLPPVPGAPGMP-----PGIPP----- 162
           SD +       S+   PQP  P Q  +P      L  VPGAP  P     P +P      
Sbjct: 435 SDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQS 494

Query: 163 ----LMPGVPPLMPGMPPVMPGMP-PGMMPMGGMMPPGPGIP--------PLMPGMPP-- 207
               L  G  P  P +PP+  G   P   P  G+   G G P        PL  G PP  
Sbjct: 495 PSEGLGMGAGPACP-LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553

Query: 208 ---------------GMPPP---VPRPGIP-PMTQAQAVSAPGILNR---PPAPTATVPA 245
                          G PPP   +P PG P P         P +L     PP P+  +P 
Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPP 613

Query: 246 PQPPVTK---------PLFPSAGQ-MGTPVTSSSTASSNSESLSASSKALFP-------- 287
           P  P +           L P+AG   G+   +   +      L   S  LFP        
Sbjct: 614 PSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTL 673

Query: 288 ---STAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKP- 343
              ++A   A +  P GT  +P   +      P      A T   AS+     S + +P 
Sbjct: 674 IALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPP 733

Query: 344 -------AASITSKPATLTTT-SATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 395
                   AS+    ++LT++  A   L+ P   +   +   QL      LP  G  P  
Sbjct: 734 QLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQL------LPGGGAPPPL 787

Query: 396 NPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGG-HHQGMPGYLPGAMPPYGQGPPMVP 454
           +    P+  ++     IP +Q   P +PP         +     L    PP+G   P VP
Sbjct: 788 SEASSPLACLLQSLQ-IPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVP 846

Query: 455 PYQGGPPRPPMGMR 468
               G      G R
Sbjct: 847 ELLTGRGSGKRGRR 860


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 102/394 (25%), Positives = 129/394 (32%), Gaps = 75/394 (19%)

Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGM--------PPGIP-----------PLMPGVPP 169
           P P  P+ G   P   PG P  PG PGM        P GIP           P  PG P 
Sbjct: 83  PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 170 LM-PGMPPVMPGM--PPGMM-------PMGGMMPPGP----------GIP-PLMPGMPPG 208
           L  P  PP +PGM   PG +       P G    PGP          GIP P+ P  PPG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 209 MPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATVPAPQPPVTKPLFPSAGQ 260
           +  P   PG+P       ++  G         L  PP P   +   + P+        G 
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF--QKGD 259

Query: 261 MGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTE 316
            G P                      P   + +   QG  G   KP     N  P     
Sbjct: 260 QGLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 317 PPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERR 376
           P  P +P             ++    P   +  +P T  T      +  P       ER 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 377 AQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
               +    LP P  A +  PP GP        PG P ++G +    P G       G+ 
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 437 GY--LPGAMPPYGQGPPMVPP----YQGGPPRPP 464
           G    PG   P G   P +PP     + GPP PP
Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP 459



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 105/376 (27%), Positives = 128/376 (34%), Gaps = 83/376 (22%)

Query: 141  PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGMM 186
            P   PG+P  PGAPG P  I    PP  PG P          P  PG PP +PG    + 
Sbjct: 714  PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGALG 772

Query: 187  PMGGMMPPGPGIPPLMPGM--------------------PPGMP------PPVPRPGIP- 219
            P G    PGP  PP   G+                    PPG+P      PP P PGIP 
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP-PGIPG 831

Query: 220  PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSA-GQMGTPVTSSSTASSNSESL 278
            P+ Q      PG    P  P   VP P      P  P A G +G P +      + +   
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG- 890

Query: 279  SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-----TQSTASTT 333
                   FP T + +  + GP G         P     P +   P        Q      
Sbjct: 891  -------FPGT-KGEMGMMGPPG--------PPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 334  STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQA 392
              T    +K    +   P  +      SK    +  +         PK  + LP  PGQ 
Sbjct: 935  GPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQP 993

Query: 393  PI-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYG 447
             + G P    P GP G      PG+P Q G+  P    G  G    G PG      PP  
Sbjct: 994  GLSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP-- 1044

Query: 448  QGPPMVPPYQGGPPRP 463
             GP  VP   G P  P
Sbjct: 1045 -GPSGVPGQPGSPGLP 1059



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 105/391 (26%), Positives = 141/391 (36%), Gaps = 75/391 (19%)

Query: 135  QQGYIPPMAQPGLPPVPGAPGMP-----------PGIP-----------PLMPGVP-PLM 171
            + G + P   PG   +PG  G+P           PG+P           P +PG P P+ 
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 172  PGM--------PPVMPGMPPGMMPMGGMMPPG-PGIPPL--MPGMPPGMPPPVPRPGIPP 220
            P +         P +PG+P    P G    PG PG P L   PG+ PG P P   PG+P 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGPKGNPGLP- 1014

Query: 221  MTQAQAVSAPGILNRPPAPTATV-----PAPQPPVTKPLFPSA--GQMGTPVTSSSTASS 273
                     PG++  PP    T+     P PQ  V  P  PS   GQ G+P         
Sbjct: 1015 -------GQPGLIG-PPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 274  NSESLSASSKALFPSTA--------QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPA 324
                +S+      P                ++G VG    P L  TP    +P  P FP 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP- 1124

Query: 325  YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 384
                T         +       +  +P  +       +   P E     +     P  Q+
Sbjct: 1125 ---GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 385  NLPRPGQAPIGNPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGY 438
                PGQ   GNP    + G+   +     PGIP   G+  P    G +G    QG PG 
Sbjct: 1182 G--EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG- 1238

Query: 439  LPGAMPPYGQGPPMVPPYQGGPPRP-PMGMR 468
             PG+  P  +GP   P  QG P RP P G +
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 103/403 (25%), Positives = 128/403 (31%), Gaps = 87/403 (21%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV-----------PPLMPGMPPV- 177
           Q G   P   PG+P  PGAPG P     PG     PG+            P +PG+P   
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 178 ----MPGMPPGMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPG 231
               +PG+P      GG+   G   PP  PG+P  PG   P+  PG  P          G
Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQG 638

Query: 232 ILNRPPAPTATVPAPQPPVT-----KPLFPS----------------AGQMGTPVTSSST 270
           +   P  P    P   P  T     KP  P                  GQ G P    S 
Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698

Query: 271 ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTEPPKPTFPAYT 326
                  +        P   +    + GP G    P    L   P     P     P + 
Sbjct: 699 GEPGIPGIGLPG----PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 327 ----QSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 382
                          +   K        P     T     L  P  D+    +    P  
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPG--PMG 811

Query: 383 QRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
              LP  G Q P G P + GPIG  G+  +P + G P   G+  P PP        +G P
Sbjct: 812 PPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP------GERGSP 865

Query: 437 GYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 464
           G +PGA  P G  G P +P   G              GPP PP
Sbjct: 866 G-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 98/367 (26%), Positives = 127/367 (34%), Gaps = 57/367 (15%)

Query: 136  QGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP-----PLMPGMPPVM--PGMPPGMMPM 188
            +G + P  QPG    PG PG+    PP  PG+P     P + G+P     PG PPG+   
Sbjct: 798  KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG-PPGLDVP 856

Query: 189  GGMMPPG----PGIP----PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
            G   PPG    PGIP    P+ P   PG+P      G P       +  P     PP P 
Sbjct: 857  G---PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP---PGPPGPL 910

Query: 241  ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA------ 294
                    P  K      GQ G P  +    S     L      + P+   ++       
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 295  -----AVQGPVGTDFKPLN-STPATTTEP--PKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
                  V GP G    P +   P  + +P  P P  P                  K    
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 347  ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV-GPIGGM 405
                P              P +  S       LP  + +   PG + IG P + GP G  
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGS-----PGLPGQKGDKGDPGISSIGLPGLPGPKG-- 1083

Query: 406  MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQG--GPPRP 463
             P  PG P   G++      G  G    G+PG LPG   P  +G P +P + G  GPP P
Sbjct: 1084 EPGLPGYPGNPGIK------GSVG--DPGLPG-LPGT--PGAKGQPGLPGFPGTPGPPGP 1132

Query: 464  PMGMRPP 470
                 PP
Sbjct: 1133 KGISGPP 1139



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 108/401 (26%), Positives = 137/401 (34%), Gaps = 79/401 (19%)

Query: 129  PQPVQPQQGYIPPMAQPGLPPVPGAPG--MPPGIPPL-MPGVP-----PLMPGMP----- 175
            PQ V+   G      QPG P +PG  G    PGI  + +PG+P     P +PG P     
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 176  ------PVMPGMP--PGMMPMGGMM-------PPGP-GI--PPLMPGMPPGMPPPVPRPG 217
                  P +PG+P  PG     G+        PPGP GI  PP  PG+ PG P PV   G
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL-PGEPGPVGGGG 1155

Query: 218  IPPMTQAQAVSAPGILNRPPAPTATVPAPQP-PVTKPLFPSAGQMGTPVTSSSTASSNSE 276
             P          PG   +P       PA Q     +P F + G  G P  S         
Sbjct: 1156 HPGQP-----GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 277  SLSASSKALFPSTA---QAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTT 333
             +  +     P           VQGP G        +P    E PK              
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPP-----GSPGPALEGPKG-----NPGPQGPP 1260

Query: 334  STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAP 393
                 T  +        P          +  +P      +     LP  + +   PG   
Sbjct: 1261 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPG-----QPGLPGLPGLKGDQGPPGLQ- 1314

Query: 394  IGNPPVGPIGGMM--PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYL-----PGAMPPY 446
             GNP    + GM   P  PG+P   GM+ P    G  G   +G PG +     PG   P 
Sbjct: 1315 -GNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG--PEGEPGLIGPPGPPGLPGPS 1371

Query: 447  GQ--------GPPMVPPYQG--GPPRP--PMGMRPPVMSQG 475
            GQ        GPP +P   G  G P P  P G+  P    G
Sbjct: 1372 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1412



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 100/379 (26%), Positives = 130/379 (34%), Gaps = 77/379 (20%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----------PGIPPLMPGV--PPLMPGMP--PVMP 179
           ++G+      PGLP  PG  G P           PG PP   G+  PP +PG P  P +P
Sbjct: 49  ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPG-PPGPKGIRGPPGLPGFPGTPGLP 107

Query: 180 GMP-----PGMMPMGGM--------MPPGPGIPPLM-PGMPPGMPPPVPRPGIPPMTQAQ 225
           GMP     PG   + G          P  PG P L  P  PPG+P     PG   M+   
Sbjct: 108 GMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLP 167

Query: 226 AVSA-PGILNRP-----PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLS 279
                PG    P     P PT  +P P  P   P     G MG P          +  L+
Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTG-IPGPIGPPGPP-----GLMGPPGPPGLPGPKGNMGLN 221

Query: 280 ASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNST 339
                  P   + +  +QGP G         P   +E  +P    + +            
Sbjct: 222 FQG----PKGEKGEQGLQGPPG--------PPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 340 AAK----PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 395
                  P      +           K   P +D   E  +  +P    +   PG+ P  
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD--GENGQPGIPGLPGDPGYPGE-PGR 326

Query: 396 NPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGH--HQGMPGYLPGAMPPYG----QG 449
           +   G  G   PP P      G+  P P  G   G   + G+PG LPG     G    QG
Sbjct: 327 DGEKGQKGDTGPPGP-----PGLVIPRPGTGITIGEKGNIGLPG-LPGEKGERGFPGIQG 380

Query: 450 PPMVPPYQG----GPPRPP 464
           PP +P   G    GPP PP
Sbjct: 381 PPGLPGPPGAAVMGPPGPP 399



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 115/424 (27%), Positives = 141/424 (33%), Gaps = 103/424 (24%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGV--------PP--LMPGMPPVMPGMPPG 184
           ++G+      PGLP  PGA  M P  PP  PG         PP   +PG PP + G P  
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG-PPGLDGQPGA 430

Query: 185 MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSA--------------- 229
               G   P GP IPP      PG P P   PG   +   Q V                 
Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 230 -----PGILNRPPAP---------------TATVPAPQPPVT----KPLFP-SAGQMGTP 264
                PG+   P  P                AT P   P +      P FP S G+ G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 265 VTSSSTASSNSESLSASSKAL--FPSTAQAQAAVQG-------PVGTDFKPLNSTPATTT 315
           +T         E  S  +  L   P T   Q  + G       P G  FK     P    
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 316 EPPKPTF------PAYTQSTASTTSTTNSTAAKPAASITSKP-----ATLTTTSATSKLI 364
            P  P        P +              A  P       P      T+T         
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 365 HP--DEDISLE-----ERRAQLPKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGI 412
           +P  D D+ L        +  LP    +   PG   IG P P GP G  G+   P  PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 413 PQQQGMRPPMPPHGQYGGHHQGMPGY-LPGAMPPYGQGPPMVPPYQG-----------GP 460
           P + G+  P  P G  G   +G PG+ LPG  PP   GPP +P ++G           GP
Sbjct: 730 PGRIGLEGPPGPPGFPG--PKGEPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGP 782

Query: 461 PRPP 464
           P PP
Sbjct: 783 PGPP 786



 Score = 55.8 bits (133), Expect = 8e-08
 Identities = 97/381 (25%), Positives = 119/381 (31%), Gaps = 98/381 (25%)

Query: 144  QPGLPPVPGAPGMPPGI-----PPLMPGVP-----------PLMPGMP-----PVMPGMP 182
            QPGLP  PG PG PPG      PP  PG+P           P  PG P     P   G+P
Sbjct: 1117 QPGLPGFPGTPG-PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP 1175

Query: 183  --------PGMMPMGGMMPPG-PGIPPL-----MPGMP--PGMPPPVPRPGIPPMTQAQA 226
                    PG    G   PPG PG+        +PG+P  PG+P P   PG         
Sbjct: 1176 GPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF----- 1230

Query: 227  VSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALF 286
               PG+   P  P +  PA + P   P     G  G P     T                
Sbjct: 1231 ---PGVQGPPGPPGSPGPALEGPKGNP-----GPQGPPGRPGPTGFQGLPGPEG------ 1276

Query: 287  PSTAQAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTSTTNSTAAKPAA 345
            P        ++G  G   +P L   P    +   P      Q                  
Sbjct: 1277 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL----QGNPGRPGLNGMKGDPGLP 1332

Query: 346  SITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRP-GQAPIGNPPVGPIGG 404
             +   P  +   S       P+ +  L       P     LP P GQ+ I     GP   
Sbjct: 1333 GVPGFPG-MKGPSGVPGSAGPEGEPGLIG-----PPGPPGLPGPSGQSIIIKGDAGP--- 1383

Query: 405  MMPPQPGIPQQQGMRPPMPPHGQYG----------GHHQGMPGY-----------LPGAM 443
                 PGIP Q G++    P G  G              G+PG+           LPG  
Sbjct: 1384 -----PGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1438

Query: 444  PPYGQGPPMVPPYQGGPPRPP 464
               G   P  P    GPP PP
Sbjct: 1439 GTRGLDGPPGPDGLQGPPGPP 1459



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 106/394 (26%), Positives = 128/394 (32%), Gaps = 99/394 (25%)

Query: 137 GYIPPMAQPGLPPVPGAPGMP--PGI-----------PPLMPGVPPLMPGMP--PVMPGM 181
           G   P  QPGLP +PG PG    PG            P  +PG+P   PG P  P   G 
Sbjct: 488 GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA-PGAPGFPGSKGE 546

Query: 182 PPGMMPMGGMM--------PPGPGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVS 228
           P  ++   GM         P  PG+P L PG P     PG+P P   PG   +T      
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERG 603

Query: 229 APGILNRPPAPTATVPA-------PQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSAS 281
            PG    P  P    P        P P   K +   AG  G P           ++++  
Sbjct: 604 PPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-QTITQP 662

Query: 282 SKALFPSTA--QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 338
            K   P          + G  G   +P L   P +  EP  P                  
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-----------GLPGP 711

Query: 339 TAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP- 397
              K    I   P    T             I LE               PG  P G P 
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGR----------IGLEGP-------------PG--PPGFPG 746

Query: 398 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPY 446
           P G  G  +P  PG P   G +  + P G  G    G PG         LPG    + P 
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 447 GQGPPMVPP-----YQGGPPRPPMGMRPPVMSQG 475
           GQ  PM PP        GPP PP G+  P+   G
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPP-GIPGPIGQPG 837



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 48/135 (35%), Positives = 57/135 (42%), Gaps = 30/135 (22%)

Query: 145  PGLPPVPGAPGM--PPGIPPLMPGVPPLMPGM--PPVMPGMP----PGMMPMGGMMPPG- 195
            PGLP VPG PGM  P G+P      P   PG+  PP  PG+P      ++  G   PPG 
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1386

Query: 196  PGIPPL--MPGM--PPGMPPPVPRPGIPPMTQAQAVSA-------PGI--------LNRP 236
            PG P L  +PG   P G+P P   PG P                 PG+        L+ P
Sbjct: 1387 PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGP 1446

Query: 237  PAPTATVPAPQPPVT 251
            P P      P PP T
Sbjct: 1447 PGPDGLQGPPGPPGT 1461



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)

Query: 384 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 425
           + LP P   P    P GP G M PP  PG+P                  +QG++ P  P 
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241

Query: 426 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 474
           GQ                QG+PG          +GPP  PP   GPP PP G +     Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291

Query: 475 G 475
           G
Sbjct: 292 G 292



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)

Query: 387 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 434
           P P   P  N   G  G   P  PG P  QG  PP PP      G+ G          +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 435 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 470
            PGY PG  PP  QG P      G  GPP PP  M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 410 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 465
           PG+P   G   P  P GQ G    G+PG  PG  P   +GPP +P + G P  P M
Sbjct: 59  PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 102/394 (25%), Positives = 129/394 (32%), Gaps = 75/394 (19%)

Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGM--------PPGIP-----------PLMPGVPP 169
           P P  P+ G   P   PG P  PG PGM        P GIP           P  PG P 
Sbjct: 83  PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 170 LM-PGMPPVMPGM--PPGMM-------PMGGMMPPGP----------GIP-PLMPGMPPG 208
           L  P  PP +PGM   PG +       P G    PGP          GIP P+ P  PPG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 209 MPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATVPAPQPPVTKPLFPSAGQ 260
           +  P   PG+P       ++  G         L  PP P   +   + P+        G 
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF--QKGD 259

Query: 261 MGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTE 316
            G P                      P   + +   QG  G   KP     N  P     
Sbjct: 260 QGLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 317 PPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERR 376
           P  P +P             ++    P   +  +P T  T      +  P       ER 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 377 AQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
               +    LP P  A +  PP GP        PG P ++G +    P G       G+ 
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 437 GY--LPGAMPPYGQGPPMVPP----YQGGPPRPP 464
           G    PG   P G   P +PP     + GPP PP
Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP 459



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 105/376 (27%), Positives = 128/376 (34%), Gaps = 83/376 (22%)

Query: 141  PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGMM 186
            P   PG+P  PGAPG P  I    PP  PG P          P  PG PP +PG    + 
Sbjct: 714  PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGALG 772

Query: 187  PMGGMMPPGPGIPPLMPGM--------------------PPGMP------PPVPRPGIP- 219
            P G    PGP  PP   G+                    PPG+P      PP P PGIP 
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP-PGIPG 831

Query: 220  PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSA-GQMGTPVTSSSTASSNSESL 278
            P+ Q      PG    P  P   VP P      P  P A G +G P +      + +   
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG- 890

Query: 279  SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-----TQSTASTT 333
                   FP T + +  + GP G         P     P +   P        Q      
Sbjct: 891  -------FPGT-KGEMGMMGPPG--------PPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 334  STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQA 392
              T    +K    +   P  +      SK    +  +         PK  + LP  PGQ 
Sbjct: 935  GPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQP 993

Query: 393  PI-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYG 447
             + G P    P GP G      PG+P Q G+  P    G  G    G PG      PP  
Sbjct: 994  GLSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP-- 1044

Query: 448  QGPPMVPPYQGGPPRP 463
             GP  VP   G P  P
Sbjct: 1045 -GPSGVPGQPGSPGLP 1059



 Score = 72.8 bits (177), Expect = 6e-13
 Identities = 107/400 (26%), Positives = 143/400 (35%), Gaps = 76/400 (19%)

Query: 135  QQGYIPPMAQPGLPPVPGAPGMP-----------PGIP-----------PLMPGVP-PLM 171
            + G + P   PG   +PG  G+P           PG+P           P +PG P P+ 
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 172  PGM--------PPVMPGMPPGMMPMGGMMPPG-PGIPPL--MPGMPPGMPPPVPRPGIPP 220
            P +         P +PG+P    P G    PG PG P L   PG+ PG P P   PG+P 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGPKGNPGLP- 1014

Query: 221  MTQAQAVSAPGILNRPPAPTATV-----PAPQPPVTKPLFPSA--GQMGTPVTSSSTASS 273
                     PG++  PP    T+     P PQ  V  P  PS   GQ G+P         
Sbjct: 1015 -------GQPGLIG-PPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 274  NSESLSASSKALFPSTA--------QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPA 324
                +S+      P                ++G VG    P L  TP    +P  P FP 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP- 1124

Query: 325  YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 384
                T         +       +  +P  +       +   P E     +     P  Q+
Sbjct: 1125 ---GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 385  NLPRPGQAPIGNPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGY 438
                PGQ   GNP    + G+   +     PGIP   G+  P    G +G    QG PG 
Sbjct: 1182 G--EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG- 1238

Query: 439  LPGAMPPYGQGPPMVPPYQGGPPRP--PMGMRPPVMSQGG 476
             PG+  P  +GP   P  QG P RP  P    PP +   G
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 105/380 (27%), Positives = 127/380 (33%), Gaps = 83/380 (21%)

Query: 142  MAQPGLPPVPGAPGMP--PGIP--PLMPGVP-PLMPGMPPVMPGMPPGMMPMGGMMPPG- 195
            +  PGLP +PG PG    PG+P  P  PG P P     PP  PG+P    P+GG   PG 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 196  PGIP--------------------PLMPGM----PPGMP-----------PPVP-RPGIP 219
            PG P                    P  PG     PPG+P           P +P  PG+P
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219

Query: 220  -PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESL 278
             P  +      PG+   P  P +  PA + P   P     G  G P             L
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNP-----GPQGPPGRPGLPGPEGPPGL 1274

Query: 279  SASSKALFPSTAQAQAAV---------QGPVGTDFKP----LNSTPATTTEPPKPTFPAY 325
              +           Q  +         QGP G    P    LN        P  P FP  
Sbjct: 1275 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG- 1333

Query: 326  TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
                 S    +     +P       P  L   S  S +I  D        +  L    + 
Sbjct: 1334 -MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL----KG 1388

Query: 386  LPRPGQAPIGNP-PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMP 444
            LP P Q P G P P GP        PG P + G+     P     G  +G PG LPG   
Sbjct: 1389 LPGP-QGPQGLPGPTGP--------PGDPGRNGL-----PGFDGAGGRKGDPG-LPGQPG 1433

Query: 445  PYGQGPPMVPPYQGGPPRPP 464
              G   P  P    GPP PP
Sbjct: 1434 TRGLDGPPGPDGLQGPPGPP 1453



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 103/403 (25%), Positives = 128/403 (31%), Gaps = 87/403 (21%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV-----------PPLMPGMPPV- 177
           Q G   P   PG+P  PGAPG P     PG     PG+            P +PG+P   
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 178 ----MPGMPPGMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPG 231
               +PG+P      GG+   G   PP  PG+P  PG   P+  PG  P          G
Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQG 638

Query: 232 ILNRPPAPTATVPAPQPPVT-----KPLFPS----------------AGQMGTPVTSSST 270
           +   P  P    P   P  T     KP  P                  GQ G P    S 
Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698

Query: 271 ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTEPPKPTFPAYT 326
                  +        P   +    + GP G    P    L   P     P     P + 
Sbjct: 699 GEPGIPGIGLPG----PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 327 ----QSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 382
                          +   K        P     T     L  P  D+    +    P  
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPG--PMG 811

Query: 383 QRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
              LP  G Q P G P + GPIG  G+  +P + G P   G+  P PP        +G P
Sbjct: 812 PPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP------GERGSP 865

Query: 437 GYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 464
           G +PGA  P G  G P +P   G              GPP PP
Sbjct: 866 G-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 98/367 (26%), Positives = 127/367 (34%), Gaps = 57/367 (15%)

Query: 136  QGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP-----PLMPGMPPVM--PGMPPGMMPM 188
            +G + P  QPG    PG PG+    PP  PG+P     P + G+P     PG PPG+   
Sbjct: 798  KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG-PPGLDVP 856

Query: 189  GGMMPPG----PGIP----PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
            G   PPG    PGIP    P+ P   PG+P      G P       +  P     PP P 
Sbjct: 857  G---PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP---PGPPGPL 910

Query: 241  ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA------ 294
                    P  K      GQ G P  +    S     L      + P+   ++       
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 295  -----AVQGPVGTDFKPLN-STPATTTEP--PKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
                  V GP G    P +   P  + +P  P P  P                  K    
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 347  ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV-GPIGGM 405
                P              P +  S       LP  + +   PG + IG P + GP G  
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGS-----PGLPGQKGDKGDPGISSIGLPGLPGPKG-- 1083

Query: 406  MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQG--GPPRP 463
             P  PG P   G++      G  G    G+PG LPG   P  +G P +P + G  GPP P
Sbjct: 1084 EPGLPGYPGNPGIK------GSVG--DPGLPG-LPGT--PGAKGQPGLPGFPGTPGPPGP 1132

Query: 464  PMGMRPP 470
                 PP
Sbjct: 1133 KGISGPP 1139



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 105/397 (26%), Positives = 134/397 (33%), Gaps = 77/397 (19%)

Query: 129  PQPVQPQQGYIPPMAQPGLPPVPGAPG--MPPGIPPL-MPGVP-----PLMPGMP----- 175
            PQ V+   G      QPG P +PG  G    PGI  + +PG+P     P +PG P     
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 176  ------PVMPGMP--PGMMPMGGMM-------PPGP-GI--PPLMPGMPPGMPPPVPRPG 217
                  P +PG+P  PG     G+        PPGP GI  PP  PG+ PG P PV   G
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL-PGEPGPVGGGG 1155

Query: 218  IPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSES 277
             P          PG   +P      +P P     +P  P  G  G P     +       
Sbjct: 1156 HPGQP-----GPPGEKGKPGQD--GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 278  LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 337
            L                 + GP G      +  P     P  P  P              
Sbjct: 1209 LPG---------IPGNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 338  STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 397
                +P       P  L         I  ++    +     LP  + +   PG    GNP
Sbjct: 1258 GPPGRPGLPGPEGPPGLPGNGG----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQ--GNP 1311

Query: 398  PVGPIGGMM--PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYL-----PGAMPPYGQ-- 448
                + GM   P  PG+P   GM+ P    G  G   +G PG +     PG   P GQ  
Sbjct: 1312 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG--PEGEPGLIGPPGPPGLPGPSGQSI 1369

Query: 449  ------GPPMVPPYQG--GPPRP--PMGMRPPVMSQG 475
                  GPP +P   G  G P P  P G+  P    G
Sbjct: 1370 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1406



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 100/379 (26%), Positives = 130/379 (34%), Gaps = 77/379 (20%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----------PGIPPLMPGV--PPLMPGMP--PVMP 179
           ++G+      PGLP  PG  G P           PG PP   G+  PP +PG P  P +P
Sbjct: 49  ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPG-PPGPKGIRGPPGLPGFPGTPGLP 107

Query: 180 GMP-----PGMMPMGGM--------MPPGPGIPPLM-PGMPPGMPPPVPRPGIPPMTQAQ 225
           GMP     PG   + G          P  PG P L  P  PPG+P     PG   M+   
Sbjct: 108 GMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLP 167

Query: 226 AVSA-PGILNRP-----PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLS 279
                PG    P     P PT  +P P  P   P     G MG P          +  L+
Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTG-IPGPIGPPGPP-----GLMGPPGPPGLPGPKGNMGLN 221

Query: 280 ASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNST 339
                  P   + +  +QGP G         P   +E  +P    + +            
Sbjct: 222 FQG----PKGEKGEQGLQGPPG--------PPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 340 AAK----PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 395
                  P      +           K   P +D   E  +  +P    +   PG+ P  
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD--GENGQPGIPGLPGDPGYPGE-PGR 326

Query: 396 NPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGH--HQGMPGYLPGAMPPYG----QG 449
           +   G  G   PP P      G+  P P  G   G   + G+PG LPG     G    QG
Sbjct: 327 DGEKGQKGDTGPPGP-----PGLVIPRPGTGITIGEKGNIGLPG-LPGEKGERGFPGIQG 380

Query: 450 PPMVPPYQG----GPPRPP 464
           PP +P   G    GPP PP
Sbjct: 381 PPGLPGPPGAAVMGPPGPP 399



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 115/424 (27%), Positives = 141/424 (33%), Gaps = 103/424 (24%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGV--------PP--LMPGMPPVMPGMPPG 184
           ++G+      PGLP  PGA  M P  PP  PG         PP   +PG PP + G P  
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG-PPGLDGQPGA 430

Query: 185 MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSA--------------- 229
               G   P GP IPP      PG P P   PG   +   Q V                 
Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 230 -----PGILNRPPAP---------------TATVPAPQPPVT----KPLFP-SAGQMGTP 264
                PG+   P  P                AT P   P +      P FP S G+ G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 265 VTSSSTASSNSESLSASSKAL--FPSTAQAQAAVQG-------PVGTDFKPLNSTPATTT 315
           +T         E  S  +  L   P T   Q  + G       P G  FK     P    
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 316 EPPKPTF------PAYTQSTASTTSTTNSTAAKPAASITSKP-----ATLTTTSATSKLI 364
            P  P        P +              A  P       P      T+T         
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 365 HP--DEDISLE-----ERRAQLPKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGI 412
           +P  D D+ L        +  LP    +   PG   IG P P GP G  G+   P  PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 413 PQQQGMRPPMPPHGQYGGHHQGMPGY-LPGAMPPYGQGPPMVPPYQG-----------GP 460
           P + G+  P  P G  G   +G PG+ LPG  PP   GPP +P ++G           GP
Sbjct: 730 PGRIGLEGPPGPPGFPG--PKGEPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGP 782

Query: 461 PRPP 464
           P PP
Sbjct: 783 PGPP 786



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 106/394 (26%), Positives = 128/394 (32%), Gaps = 99/394 (25%)

Query: 137 GYIPPMAQPGLPPVPGAPGMP--PGI-----------PPLMPGVPPLMPGMP--PVMPGM 181
           G   P  QPGLP +PG PG    PG            P  +PG+P   PG P  P   G 
Sbjct: 488 GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA-PGAPGFPGSKGE 546

Query: 182 PPGMMPMGGMM--------PPGPGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVS 228
           P  ++   GM         P  PG+P L PG P     PG+P P   PG   +T      
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERG 603

Query: 229 APGILNRPPAPTATVPA-------PQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSAS 281
            PG    P  P    P        P P   K +   AG  G P           ++++  
Sbjct: 604 PPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-QTITQP 662

Query: 282 SKALFPSTA--QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 338
            K   P          + G  G   +P L   P +  EP  P                  
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-----------GLPGP 711

Query: 339 TAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP- 397
              K    I   P    T             I LE               PG  P G P 
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGR----------IGLEGP-------------PG--PPGFPG 746

Query: 398 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPY 446
           P G  G  +P  PG P   G +  + P G  G    G PG         LPG    + P 
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 447 GQGPPMVPP-----YQGGPPRPPMGMRPPVMSQG 475
           GQ  PM PP        GPP PP G+  P+   G
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPP-GIPGPIGQPG 837



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/123 (34%), Positives = 52/123 (42%), Gaps = 17/123 (13%)

Query: 137  GYIPPMAQPGLPPVPGAPGM--PPGIPPLMPG--VPPLMPGMPPVMPGMPPGMMPMGGMM 192
            G   P  +PGL   PG PG+  P G   ++ G   PP +PG P  + G+P    P G   
Sbjct: 1342 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-LKGLPG---PQGPQG 1397

Query: 193  PPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPGI--LNRPPAPTATVPAPQP 248
             PGP  PP  PG    PG      R G P +        PG   L+ PP P      P P
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP-----GQPGTRGLDGPPGPDGLQGPPGP 1452

Query: 249  PVT 251
            P T
Sbjct: 1453 PGT 1455



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)

Query: 384 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 425
           + LP P   P    P GP G M PP  PG+P                  +QG++ P  P 
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241

Query: 426 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 474
           GQ                QG+PG          +GPP  PP   GPP PP G +     Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291

Query: 475 G 475
           G
Sbjct: 292 G 292



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)

Query: 387 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 434
           P P   P  N   G  G   P  PG P  QG  PP PP      G+ G          +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 435 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 470
            PGY PG  PP  QG P      G  GPP PP  M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 410 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 465
           PG+P   G   P  P GQ G    G+PG  PG  P   +GPP +P + G P  P M
Sbjct: 59  PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 102/394 (25%), Positives = 129/394 (32%), Gaps = 75/394 (19%)

Query: 129 PQPVQPQQGYIPPMAQPGLPPVPGAPGM--------PPGIP-----------PLMPGVPP 169
           P P  P+ G   P   PG P  PG PGM        P GIP           P  PG P 
Sbjct: 83  PGPPGPK-GIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 170 LM-PGMPPVMPGM--PPGMM-------PMGGMMPPGP----------GIP-PLMPGMPPG 208
           L  P  PP +PGM   PG +       P G    PGP          GIP P+ P  PPG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 209 MPPPVPRPGIPPMTQAQAVSAPGI--------LNRPPAPTATVPAPQPPVTKPLFPSAGQ 260
           +  P   PG+P       ++  G         L  PP P   +   + P+        G 
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF--QKGD 259

Query: 261 MGTPVTSSSTASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTE 316
            G P                      P   + +   QG  G   KP     N  P     
Sbjct: 260 QGLPGDRGPPGPPGIRGPPGP-----PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 317 PPKPTFPAYTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERR 376
           P  P +P             ++    P   +  +P T  T      +  P       ER 
Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 377 AQLPKYQRNLPRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
               +    LP P  A +  PP GP        PG P ++G +    P G       G+ 
Sbjct: 375 FPGIQGPPGLPGPPGAAVMGPP-GP--------PGFPGERGQKGDEGPPGISIPGPPGLD 425

Query: 437 GY--LPGAMPPYGQGPPMVPP----YQGGPPRPP 464
           G    PG   P G   P +PP     + GPP PP
Sbjct: 426 GQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPP 459



 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 105/376 (27%), Positives = 128/376 (34%), Gaps = 83/376 (22%)

Query: 141  PMAQPGLPPVPGAPGMPPGI----PPLMPGVP----------PLMPGMPPVMPGMPPGMM 186
            P   PG+P  PGAPG P  I    PP  PG P          P  PG PP +PG    + 
Sbjct: 714  PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPG-PPGLPGFKGALG 772

Query: 187  PMGGMMPPGPGIPPLMPGM--------------------PPGMP------PPVPRPGIP- 219
            P G    PGP  PP   G+                    PPG+P      PP P PGIP 
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP-PGIPG 831

Query: 220  PMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSA-GQMGTPVTSSSTASSNSESL 278
            P+ Q      PG    P  P   VP P      P  P A G +G P +      + +   
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG- 890

Query: 279  SASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAY-----TQSTASTT 333
                   FP T + +  + GP G         P     P +   P        Q      
Sbjct: 891  -------FPGT-KGEMGMMGPPG--------PPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 334  STTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLP-RPGQA 392
              T    +K    +   P  +      SK    +  +         PK  + LP  PGQ 
Sbjct: 935  GPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP-GIPGVSGPKGYQGLPGDPGQP 993

Query: 393  PI-GNP----PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYG 447
             + G P    P GP G      PG+P Q G+  P    G  G    G PG      PP  
Sbjct: 994  GLSGQPGLPGPPGPKG-----NPGLPGQPGLIGPPGLKGTIG--DMGFPGPQGVEGPP-- 1044

Query: 448  QGPPMVPPYQGGPPRP 463
             GP  VP   G P  P
Sbjct: 1045 -GPSGVPGQPGSPGLP 1059



 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 103/385 (26%), Positives = 138/385 (35%), Gaps = 74/385 (19%)

Query: 135  QQGYIPPMAQPGLPPVPGAPGMP-----------PGIP-----------PLMPGVP-PLM 171
            + G + P   PG   +PG  G+P           PG+P           P +PG P P+ 
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 172  PGM--------PPVMPGMPPGMMPMGGMMPPG-PGIPPL--MPGMPPGMPPPVPRPGIPP 220
            P +         P +PG+P    P G    PG PG P L   PG+ PG P P   PG+P 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL-PGPPGPKGNPGLP- 1014

Query: 221  MTQAQAVSAPGILNRPPAPTATV-----PAPQPPVTKPLFPSA--GQMGTPVTSSSTASS 273
                     PG++  PP    T+     P PQ  V  P  PS   GQ G+P         
Sbjct: 1015 -------GQPGLIG-PPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 274  NSESLSASSKALFPSTA--------QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPA 324
                +S+      P                ++G VG    P L  TP    +P  P FP 
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFP- 1124

Query: 325  YTQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQR 384
                T         +       +  +P  +       +   P E     +     P  Q+
Sbjct: 1125 ---GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 385  NLPRPGQAPIGNPPVGPIGGMMPPQ-----PGIPQQQGMRPPMPPHGQYG-GHHQGMPGY 438
                PGQ   GNP    + G+   +     PGIP   G+  P    G +G    QG PG 
Sbjct: 1182 G--EPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPG- 1238

Query: 439  LPGAMPPYGQGPPMVPPYQGGPPRP 463
             PG+  P  +GP   P  QG P RP
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRP 1263



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 107/380 (28%), Positives = 129/380 (33%), Gaps = 80/380 (21%)

Query: 142  MAQPGLPPVPGAPGMP--PGIP--PLMPGVP-PLMPGMPPVMPGMPPGMMPMGGMMPPG- 195
            +  PGLP +PG PG    PG+P  P  PG P P     PP  PG+P    P+GG   PG 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 196  PGIP--------------------PLMPGM----PPGMP-----------PPVP-RPGIP 219
            PG P                    P  PG     PPG+P           P +P  PG+P
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219

Query: 220  -PMTQAQAVSAPGILNRPPAPTATVPA---------PQPPVTKPLFPSAGQMGTPVTSSS 269
             P  +      PG+   P  P +  PA         PQ P  +P F        P     
Sbjct: 1220 GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG 1279

Query: 270  TASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTEPPKPTFPAY 325
                  E  +     L P     +   QGP G    P    LN        P  P FP  
Sbjct: 1280 NGGIKGEKGNPGQPGL-PGLPGLKGD-QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG- 1336

Query: 326  TQSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRN 385
                 S    +     +P       P  L   S  S +I  D        +  L    + 
Sbjct: 1337 -MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL----KG 1391

Query: 386  LPRPGQAPIGNP-PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMP 444
            LP P Q P G P P GP        PG P + G+     P     G  +G PG LPG   
Sbjct: 1392 LPGP-QGPQGLPGPTGP--------PGDPGRNGL-----PGFDGAGGRKGDPG-LPGQPG 1436

Query: 445  PYGQGPPMVPPYQGGPPRPP 464
              G   P  P    GPP PP
Sbjct: 1437 TRGLDGPPGPDGLQGPPGPP 1456



 Score = 62.8 bits (151), Expect = 7e-10
 Identities = 103/403 (25%), Positives = 128/403 (31%), Gaps = 87/403 (21%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----PGIPPLMPGV-----------PPLMPGMPPV- 177
           Q G   P   PG+P  PGAPG P     PG     PG+            P +PG+P   
Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 178 ----MPGMPPGMMPMGGMMPPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPG 231
               +PG+P      GG+   G   PP  PG+P  PG   P+  PG  P          G
Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQG 638

Query: 232 ILNRPPAPTATVPAPQPPVT-----KPLFPS----------------AGQMGTPVTSSST 270
           +   P  P    P   P  T     KP  P                  GQ G P    S 
Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698

Query: 271 ASSNSESLSASSKALFPSTAQAQAAVQGPVGTDFKP----LNSTPATTTEPPKPTFPAYT 326
                  +        P   +    + GP G    P    L   P     P     P + 
Sbjct: 699 GEPGIPGIGLPG----PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA 754

Query: 327 ----QSTASTTSTTNSTAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKY 382
                          +   K        P     T     L  P  D+    +    P  
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPG--PMG 811

Query: 383 QRNLPRPG-QAPIGNPPV-GPIG--GM--MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMP 436
              LP  G Q P G P + GPIG  G+  +P + G P   G+  P PP        +G P
Sbjct: 812 PPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP------GERGSP 865

Query: 437 GYLPGAMPPYG-QGPPMVPPYQG--------------GPPRPP 464
           G +PGA  P G  G P +P   G              GPP PP
Sbjct: 866 G-IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907



 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 98/367 (26%), Positives = 127/367 (34%), Gaps = 57/367 (15%)

Query: 136  QGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGVP-----PLMPGMPPVM--PGMPPGMMPM 188
            +G + P  QPG    PG PG+    PP  PG+P     P + G+P     PG PPG+   
Sbjct: 798  KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG-PPGLDVP 856

Query: 189  GGMMPPG----PGIP----PLMPGMPPGMPPPVPRPGIPPMTQAQAVSAPGILNRPPAPT 240
            G   PPG    PGIP    P+ P   PG+P      G P       +  P     PP P 
Sbjct: 857  G---PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP---PGPPGPL 910

Query: 241  ATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSASSKALFPSTAQAQA------ 294
                    P  K      GQ G P  +    S     L      + P+   ++       
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 295  -----AVQGPVGTDFKPLN-STPATTTEP--PKPTFPAYTQSTASTTSTTNSTAAKPAAS 346
                  V GP G    P +   P  + +P  P P  P                  K    
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 347  ITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNPPV-GPIGGM 405
                P              P +  S       LP  + +   PG + IG P + GP G  
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGS-----PGLPGQKGDKGDPGISSIGLPGLPGPKG-- 1083

Query: 406  MPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQG--GPPRP 463
             P  PG P   G++      G  G    G+PG LPG   P  +G P +P + G  GPP P
Sbjct: 1084 EPGLPGYPGNPGIK------GSVG--DPGLPG-LPGT--PGAKGQPGLPGFPGTPGPPGP 1132

Query: 464  PMGMRPP 470
                 PP
Sbjct: 1133 KGISGPP 1139



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 100/379 (26%), Positives = 130/379 (34%), Gaps = 77/379 (20%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMP-----------PGIPPLMPGV--PPLMPGMP--PVMP 179
           ++G+      PGLP  PG  G P           PG PP   G+  PP +PG P  P +P
Sbjct: 49  ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPG-PPGPKGIRGPPGLPGFPGTPGLP 107

Query: 180 GMP-----PGMMPMGGM--------MPPGPGIPPLM-PGMPPGMPPPVPRPGIPPMTQAQ 225
           GMP     PG   + G          P  PG P L  P  PPG+P     PG   M+   
Sbjct: 108 GMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLP 167

Query: 226 AVSA-PGILNRP-----PAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLS 279
                PG    P     P PT  +P P  P   P     G MG P          +  L+
Sbjct: 168 GPKGNPGYPGPPGIQGLPGPTG-IPGPIGPPGPP-----GLMGPPGPPGLPGPKGNMGLN 221

Query: 280 ASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTNST 339
                  P   + +  +QGP G         P   +E  +P    + +            
Sbjct: 222 FQG----PKGEKGEQGLQGPPG--------PPGQISEQKRPIDVEFQKGDQGLPGDRGPP 269

Query: 340 AAK----PAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIG 395
                  P      +           K   P +D   E  +  +P    +   PG+ P  
Sbjct: 270 GPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD--GENGQPGIPGLPGDPGYPGE-PGR 326

Query: 396 NPPVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGH--HQGMPGYLPGAMPPYG----QG 449
           +   G  G   PP P      G+  P P  G   G   + G+PG LPG     G    QG
Sbjct: 327 DGEKGQKGDTGPPGP-----PGLVIPRPGTGITIGEKGNIGLPG-LPGEKGERGFPGIQG 380

Query: 450 PPMVPPYQG----GPPRPP 464
           PP +P   G    GPP PP
Sbjct: 381 PPGLPGPPGAAVMGPPGPP 399



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 115/424 (27%), Positives = 141/424 (33%), Gaps = 103/424 (24%)

Query: 135 QQGYIPPMAQPGLPPVPGAPGMPPGIPPLMPGV--------PP--LMPGMPPVMPGMPPG 184
           ++G+      PGLP  PGA  M P  PP  PG         PP   +PG PP + G P  
Sbjct: 372 ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG-PPGLDGQPGA 430

Query: 185 MMPMGGMMPPGPGIPPLMPGMPPGMPPPVPRPGIPPMTQAQAVSA--------------- 229
               G   P GP IPP      PG P P   PG   +   Q V                 
Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 230 -----PGILNRPPAP---------------TATVPAPQPPVT----KPLFP-SAGQMGTP 264
                PG+   P  P                AT P   P +      P FP S G+ G  
Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 265 VTSSSTASSNSESLSASSKAL--FPSTAQAQAAVQG-------PVGTDFKPLNSTPATTT 315
           +T         E  S  +  L   P T   Q  + G       P G  FK     P    
Sbjct: 551 LTFPGMKGDKGELGSPGAPGLPGLPGT-PGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 316 EPPKPTF------PAYTQSTASTTSTTNSTAAKPAASITSKP-----ATLTTTSATSKLI 364
            P  P        P +              A  P       P      T+T         
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPG 669

Query: 365 HP--DEDISLE-----ERRAQLPKYQRNLPRPGQAPIGNP-PVGPIG--GM--MPPQPGI 412
           +P  D D+ L        +  LP    +   PG   IG P P GP G  G+   P  PG 
Sbjct: 670 NPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGT 729

Query: 413 PQQQGMRPPMPPHGQYGGHHQGMPGY-LPGAMPPYGQGPPMVPPYQG-----------GP 460
           P + G+  P  P G  G   +G PG+ LPG  PP   GPP +P ++G           GP
Sbjct: 730 PGRIGLEGPPGPPGFPG--PKGEPGFALPG--PP---GPPGLPGFKGALGPKGDRGFPGP 782

Query: 461 PRPP 464
           P PP
Sbjct: 783 PGPP 786



 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 104/397 (26%), Positives = 133/397 (33%), Gaps = 74/397 (18%)

Query: 129  PQPVQPQQGYIPPMAQPGLPPVPGAPG--MPPGIPPL-MPGVP-----PLMPGMP----- 175
            PQ V+   G      QPG P +PG  G    PGI  + +PG+P     P +PG P     
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 176  ------PVMPGMP--PGMMPMGGMM-------PPGP-GI--PPLMPGMPPGMPPPVPRPG 217
                  P +PG+P  PG     G+        PPGP GI  PP  PG+ PG P PV   G
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGL-PGEPGPVGGGG 1155

Query: 218  IPPMTQAQAVSAPGILNRPPAPTATVPAPQPPVTKPLFPSAGQMGTPVTSSSTASSNSES 277
             P          PG   +P      +P P     +P  P  G  G P     +       
Sbjct: 1156 HPGQP-----GPPGEKGKPGQD--GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG 1208

Query: 278  LSASSKALFPSTAQAQAAVQGPVGTDFKPLNSTPATTTEPPKPTFPAYTQSTASTTSTTN 337
            L                 + GP G      +  P     P  P  P              
Sbjct: 1209 LPG---------IPGNPGLPGPKGE--PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257

Query: 338  STAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP 397
                +P       P            I  ++    +     LP  + +   PG    GNP
Sbjct: 1258 GPPGRPGFQGLPGPEGPPGLPGNGG-IKGEKGNPGQPGLPGLPGLKGDQGPPGLQ--GNP 1314

Query: 398  PVGPIGGMM--PPQPGIPQQQGMRPPMPPHGQYGGHHQGMPGYL-----PGAMPPYGQ-- 448
                + GM   P  PG+P   GM+ P    G  G   +G PG +     PG   P GQ  
Sbjct: 1315 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG--PEGEPGLIGPPGPPGLPGPSGQSI 1372

Query: 449  ------GPPMVPPYQG--GPPRP--PMGMRPPVMSQG 475
                  GPP +P   G  G P P  P G+  P    G
Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1409



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 106/394 (26%), Positives = 128/394 (32%), Gaps = 99/394 (25%)

Query: 137 GYIPPMAQPGLPPVPGAPGMP--PGI-----------PPLMPGVPPLMPGMP--PVMPGM 181
           G   P  QPGLP +PG PG    PG            P  +PG+P   PG P  P   G 
Sbjct: 488 GISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA-PGAPGFPGSKGE 546

Query: 182 PPGMMPMGGMM--------PPGPGIPPLMPGMP-----PGMPPPVPRPGIPPMTQAQAVS 228
           P  ++   GM         P  PG+P L PG P     PG+P P   PG   +T      
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGLPGLPGPKGEPG--GITFKGERG 603

Query: 229 APGILNRPPAPTATVPA-------PQPPVTKPLFPSAGQMGTPVTSSSTASSNSESLSAS 281
            PG    P  P    P        P P   K +   AG  G P           ++++  
Sbjct: 604 PPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-QTITQP 662

Query: 282 SKALFPSTA--QAQAAVQGPVGTDFKP-LNSTPATTTEPPKPTFPAYTQSTASTTSTTNS 338
            K   P          + G  G   +P L   P +  EP  P                  
Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-----------GLPGP 711

Query: 339 TAAKPAASITSKPATLTTTSATSKLIHPDEDISLEERRAQLPKYQRNLPRPGQAPIGNP- 397
              K    I   P    T             I LE               PG  P G P 
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGR----------IGLEGP-------------PG--PPGFPG 746

Query: 398 PVGPIGGMMPPQPGIPQQQGMRPPMPPHGQYGGHHQGMPG--------YLPGA---MPPY 446
           P G  G  +P  PG P   G +  + P G  G    G PG         LPG    + P 
Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 447 GQGPPMVPP-----YQGGPPRPPMGMRPPVMSQG 475
           GQ  PM PP        GPP PP G+  P+   G
Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPP-GIPGPIGQPG 837



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 43/123 (34%), Positives = 52/123 (42%), Gaps = 17/123 (13%)

Query: 137  GYIPPMAQPGLPPVPGAPGM--PPGIPPLMPG--VPPLMPGMPPVMPGMPPGMMPMGGMM 192
            G   P  +PGL   PG PG+  P G   ++ G   PP +PG P  + G+P    P G   
Sbjct: 1345 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPG-LKGLPG---PQGPQG 1400

Query: 193  PPGPGIPPLMPGMP--PGMPPPVPRPGIPPMTQAQAVSAPGI--LNRPPAPTATVPAPQP 248
             PGP  PP  PG    PG      R G P +        PG   L+ PP P      P P
Sbjct: 1401 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP-----GQPGTRGLDGPPGPDGLQGPPGP 1455

Query: 249  PVT 251
            P T
Sbjct: 1456 PGT 1458



 Score = 36.2 bits (82), Expect = 0.067
 Identities = 37/121 (30%), Positives = 45/121 (37%), Gaps = 39/121 (32%)

Query: 384 RNLPRPGQAPIGNPPVGPIGGMMPP-QPGIPQ-----------------QQGMRPPMPPH 425
           + LP P   P    P GP G M PP  PG+P                  +QG++ P  P 
Sbjct: 182 QGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPP 241

Query: 426 GQYGGHH-----------QGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPMGMRPPVMSQ 474
           GQ                QG+PG          +GPP  PP   GPP PP G +     Q
Sbjct: 242 GQISEQKRPIDVEFQKGDQGLPG---------DRGPPG-PPGIRGPPGPPGGEKGEKGEQ 291

Query: 475 G 475
           G
Sbjct: 292 G 292



 Score = 35.0 bits (79), Expect = 0.15
 Identities = 38/98 (38%), Positives = 40/98 (40%), Gaps = 21/98 (21%)

Query: 387 PRPGQAPIGNPPVGPIGGMMPPQPGIPQQQGMRPPMPP-----HGQYGG-------HHQG 434
           P P   P  N   G  G   P  PG P  QG  PP PP      G+ G          +G
Sbjct: 116 PGPQGIPGCNGTKGERG--FPGSPGFPGLQG--PPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 435 MPGYLPGAMPPYGQGPPMVPPYQG--GPPRPPMGMRPP 470
            PGY PG  PP  QG P      G  GPP PP  M PP
Sbjct: 172 NPGY-PG--PPGIQGLPGPTGIPGPIGPPGPPGLMGPP 206



 Score = 33.9 bits (76), Expect = 0.33
 Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)

Query: 410 PGIPQQQGMRPPMPPHGQYGGHHQGMPGYLPGAMPPYGQGPPMVPPYQGGPPRPPM 465
           PG+P   G   P  P GQ G    G+PG  PG  P   +GPP +P + G P  P M
Sbjct: 59  PGLPGFPGPEGPPGPRGQKG--DDGIPG-PPG--PKGIRGPPGLPGFPGTPGLPGM 109


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.134    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,559,074
Number of Sequences: 37866
Number of extensions: 2390067
Number of successful extensions: 54794
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 801
Number of HSP's successfully gapped in prelim test: 2086
Number of HSP's that attempted gapping in prelim test: 14915
Number of HSP's gapped (non-prelim): 17824
length of query: 478
length of database: 18,247,518
effective HSP length: 106
effective length of query: 372
effective length of database: 14,233,722
effective search space: 5294944584
effective search space used: 5294944584
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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