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Search of human proteins with 4507909
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
(502 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens] 1061 0.0
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 446 e-125
gi|11386183 WAS protein family, member 2 [Homo sapiens] 124 3e-28
gi|160707881 formin 2 [Homo sapiens] 117 2e-26
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 105 1e-22
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 105 1e-22
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 102 8e-22
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 94 2e-19
gi|33356148 formin-like 1 [Homo sapiens] 92 8e-19
gi|157168329 formin 1 [Homo sapiens] 92 1e-18
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 92 1e-18
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 91 2e-18
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 91 2e-18
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 91 2e-18
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 91 2e-18
gi|150417989 cyclin K isoform 1 [Homo sapiens] 89 9e-18
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 88 2e-17
gi|153792074 proline rich 12 [Homo sapiens] 87 4e-17
gi|13699803 WAS protein family, member 3 [Homo sapiens] 86 1e-16
gi|7706501 WW domain binding protein 11 [Homo sapiens] 84 4e-16
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 83 5e-16
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 83 5e-16
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 83 5e-16
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 83 5e-16
gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2 pre... 83 7e-16
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 82 9e-16
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 82 1e-15
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 82 1e-15
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 82 1e-15
gi|39812378 RAN binding protein 9 [Homo sapiens] 81 2e-15
>gi|4507909 Wiskott-Aldrich syndrome protein [Homo sapiens]
Length = 502
Score = 1061 bits (2745), Expect = 0.0
Identities = 502/502 (100%), Positives = 502/502 (100%)
Query: 1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG 60
MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG
Sbjct: 1 MSGGPMGGRPGGRGAPAVQQNIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPG 60
Query: 61 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD 120
AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD
Sbjct: 61 AEHWTKEHCGAVCFVKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGD 120
Query: 121 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH 180
DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH
Sbjct: 121 DCQAGLNFADEDEAQAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLH 180
Query: 181 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA 240
PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA
Sbjct: 181 PGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGA 240
Query: 241 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL 300
PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL
Sbjct: 241 PSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGL 300
Query: 301 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP 360
EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP
Sbjct: 301 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP 360
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV
Sbjct: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
Query: 421 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA 480
PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA
Sbjct: 421 PAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA 480
Query: 481 IHSSDEGEDQAGDEDEDDEWDD 502
IHSSDEGEDQAGDEDEDDEWDD
Sbjct: 481 IHSSDEGEDQAGDEDEDDEWDD 502
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 446 bits (1147), Expect = e-125
Identities = 259/531 (48%), Positives = 319/531 (60%), Gaps = 90/531 (16%)
Query: 21 NIPSTLLQDHENQRLFEMLGRKCLTLATAVVQLYLALPPGAEHWTKEHCGAVCFVKDNPQ 80
N+ S LL EN+ LF LG+KC+T+++AVVQLY A W+K+ G C VKDNPQ
Sbjct: 16 NVGSLLLTPQENESLFTFLGKKCVTMSSAVVQLYAA--DRNCMWSKKCSGVACLVKDNPQ 73
Query: 81 KSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEAQAFRAL 140
+SYF+R++ ++ G+LLWEQELY+ VY++P +FHTFAGD CQ LNFA+E+EA+ FR
Sbjct: 74 RSYFLRIFDIKDGKLLWEQELYNNFVYNSPRGYFHTFAGDTCQVALNFANEEEAKKFRKA 133
Query: 141 VQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATV 200
V + + +R QR+S RR PP GP +L +ATV
Sbjct: 134 VTDLLGRR-QRKSEKRRD-----------------------------PPNGP-NLPMATV 162
Query: 201 DIQNPDITSSRYRGLPAPGPSPADKKRSGK---KKISKADIGAPSGFKHVSHVGWDPQNG 257
DI+NP+IT++R+ G S +K+ GK K+++KADIG PS F+H+ HVGWDP G
Sbjct: 163 DIKNPEITTNRFYGPQVNNISHTKEKKKGKAKKKRLTKADIGTPSNFQHIGHVGWDPNTG 222
Query: 258 FDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP 317
FD+NNLDP+L++LF GISEAQL D ETSK+IYDFIE GG+EAV+ E+RRQ P PPP
Sbjct: 223 FDLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAP--PPP 280
Query: 318 PPSRGGNQLPRPPIVGGN------KGRSGPLPP---VPLGIAPPPPTPRG-----PPPPG 363
PPSRGG P PP +GR P PP P PPPP R PPPP
Sbjct: 281 PPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPN 340
Query: 364 RGGPPPPPP-PATGRSGPLPPPPPGAG-GPPMPPPPPPPPPPPSSGNGPAPPPLPPA--- 418
R PPPPP P++ SGP PPPP G GP PPPPPPPPPPP GP PPP P+
Sbjct: 341 RMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPP----GPPPPPGLPSDGD 396
Query: 419 -LVP--AGGLAP----------------------GGGRGALLDQIRQGIQLNKTPGAPES 453
VP AG A GR ALLDQIRQGIQL ES
Sbjct: 397 HQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQES 456
Query: 454 SALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDED--EDDEWDD 502
+ P P S G+VGALM VMQKRS+AIHSSDE ED+ +ED +DDEW+D
Sbjct: 457 TPPTPAPTS--GIVGALMEVMQKRSKAIHSSDEDEDEDDEEDFEDDDEWED 505
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 124 bits (310), Expect = 3e-28
Identities = 80/201 (39%), Positives = 91/201 (45%), Gaps = 32/201 (15%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG-PPPPGRGGPPPP 370
P PPPPPP G P PP+ G+ G PPPP+P PP P PPPP
Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPG------------TPPPPSPPSFPPHPDFAAPPPP 367
Query: 371 PPPATGRSGPLPPPP---PGAGGPPMPPPPPPPPPPP-----SSGNGPAPPPLPPALVPA 422
PPP LPPPP P G PP PPPPPPP PPP + G PPPL P
Sbjct: 368 PPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQPAIPPPLSDTTKPK 427
Query: 423 GGL-APGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRAI 481
L A R LL IRQG QL + E Q +VG + + R A+
Sbjct: 428 SSLPAVSDARSDLLSAIRQGFQLRRVEEQRE--------QEKRDVVGNDVATILSRRIAV 479
Query: 482 HSSDEGEDQAGDEDEDDEWDD 502
SD ED + + DEDD W D
Sbjct: 480 EYSD-SEDDSSEFDEDD-WSD 498
Score = 56.2 bits (134), Expect = 7e-08
Identities = 36/93 (38%), Positives = 39/93 (41%), Gaps = 36/93 (38%)
Query: 359 PPPPGR---GGPPP-------PPPPA-----------TGRSGPL---------PPPPPGA 388
PPPP P P PPPPA +G +GP PPP P
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 389 GGPP------MPPPPPPPPPPPSSGNGPAPPPL 415
G PP PPP PPPPPPP G P PPP+
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPV 339
Score = 40.4 bits (93), Expect = 0.004
Identities = 42/154 (27%), Positives = 44/154 (28%), Gaps = 64/154 (41%)
Query: 371 PPPATGRSGP----------LPPPP----------------------------------- 385
PPP S LPPPP
Sbjct: 247 PPPPQSDSASSPSPSFSEDNLPPPPAEFSYPVDNQRGSGLAGPKRSSVVSPSHPPPAPPL 306
Query: 386 -------PGAGGPPMPPPPPP-----PPPPPSSG---NGPAPPPLPPALVPAGGLA---- 426
PG PP PPPPPP PPPPP G G PPP PP+ P A
Sbjct: 307 GSPPGPKPGFAPPPAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPP 366
Query: 427 PGGGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
P A + T GAP PPP
Sbjct: 367 PPPPPAADYPTLPPPPLSQPTGGAPPPPPPPPPP 400
Score = 30.0 bits (66), Expect = 5.1
Identities = 22/69 (31%), Positives = 25/69 (36%), Gaps = 8/69 (11%)
Query: 159 LPPPPTPANEERRGGLPP-----LPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYR 213
+PPPP P G PP P HP PP P + T+ P S
Sbjct: 332 IPPPPPPVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPPAADYPTLP---PPPLSQPTG 388
Query: 214 GLPAPGPSP 222
G P P P P
Sbjct: 389 GAPPPPPPP 397
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 117 bits (294), Expect = 2e-26
Identities = 75/174 (43%), Positives = 81/174 (46%), Gaps = 34/174 (19%)
Query: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPGRGG 366
E LPPPPPP G P PP+ G PLPP+P GI PPPP P PPPP G
Sbjct: 906 EMLPPPPPPLPGAGIPPPPPLPGAG---ILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA 962
Query: 367 PPPPPPPATGRSGPLPPPPPGAGGPPMPP------PPPP-------PPPPPSSGNG-PAP 412
P PPP G P PPP PGAG PP PP PPPP PPPPP G G P P
Sbjct: 963 GIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP 1022
Query: 413 PPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGL 466
PPLP A +P PG G + P P + PPP G+
Sbjct: 1023 PPLPGAGIPPPPPLPGAG-------------IPPPPPLPGAGIPPPPPLPGAGI 1063
Score = 115 bits (289), Expect = 7e-26
Identities = 73/167 (43%), Positives = 81/167 (48%), Gaps = 18/167 (10%)
Query: 312 PLP----PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPG 363
PLP PPPPP G P PP+ G P PP+P GI PPPP P PPPP
Sbjct: 969 PLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1025
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPP----PPPPPPPSSGNGPAPPPLPPAL 419
G PPPPP G P PPP PGAG PP PP P PPPPP P +G P PPPLP A
Sbjct: 1026 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-PPPPPLPGAG 1084
Query: 420 VPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGL 466
+P PG G G+ + P P + PPP G+
Sbjct: 1085 IPPPPPLPGAGIPP--PPPLPGVGIPPPPPLPGAGIPPPPPLPGAGI 1129
Score = 113 bits (283), Expect = 4e-25
Identities = 73/167 (43%), Positives = 81/167 (48%), Gaps = 18/167 (10%)
Query: 312 PLP----PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPR---GPPPPG 363
PLP PPPPP G P PP+ G P PP+P GI PPPP P PPPP
Sbjct: 1057 PLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPP----PPPPPPPSSGNGPAPPPLPPAL 419
G PPPPP G P PPP PGAG PP PP P PPPPP P +G P PPPLP A
Sbjct: 1114 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGI-PPPPPLPGAG 1172
Query: 420 VPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGL 466
+P PG G G+ + P P + PPP G+
Sbjct: 1173 IPPPPPLPGVGIPP--PPPLPGVGIPPPPPLPGAGIPPPPPLPGMGI 1217
Score = 112 bits (280), Expect = 8e-25
Identities = 76/186 (40%), Positives = 83/186 (44%), Gaps = 34/186 (18%)
Query: 312 PLP----PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP-LGIAPPPPTPRG---PPPPG 363
PLP PPPPP G P PP+ G P PP+P GI PPPP P PPPP
Sbjct: 1024 PLPGAGIPPPPPLPGAGIPPPPPLPGAG---IPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPP------PPPP-------PPPPPSSGNG- 409
G PPPPP G P PPP PG G PP PP PPPP PPPPP G G
Sbjct: 1081 PGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI 1140
Query: 410 PAPPPL------PPALVPAGGLAPG---GGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
P PPPL PP +P G+ P G G G+ + P P PPP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Query: 461 QSSEGL 466
G+
Sbjct: 1201 LPGAGI 1206
Score = 96.3 bits (238), Expect = 6e-20
Identities = 75/189 (39%), Positives = 80/189 (42%), Gaps = 51/189 (26%)
Query: 312 PLP----PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG-----PPPP 362
PLP PPPPP G P PP+ G PLP V GI PPPP P PP P
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV--GIPPPPPLPGAGIPPPPPLP 1169
Query: 363 GRGGPPPPP---------PPATGRSGPLPPPPPGAGGPPMPP----------PPPPPPPP 403
G G PPPPP PP G P PPP PGAG PP PP PP PPP
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPP- 1228
Query: 404 PSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSS 463
G G PPPL P P LL Q+ + T P+ PPP S
Sbjct: 1229 ---GTGIPPPPLLPVSGP-----------PLLPQVG-----SSTLPTPQVCGFLPPPLPS 1269
Query: 464 EGLVGALMH 472
GL G M+
Sbjct: 1270 -GLFGLGMN 1277
Score = 92.8 bits (229), Expect = 6e-19
Identities = 63/172 (36%), Positives = 74/172 (43%), Gaps = 36/172 (20%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGP---P 368
P PPP P + + +P +V P PP+P P P+ P PP G P
Sbjct: 856 PSPPPLPCTESSSSMPGLGMV------PPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLP 909
Query: 369 PPPPPATGRSGPLPPPPPGAGGPPMPP------PPPP-------PPPPPSSGNG-PAPPP 414
PPPPP G P PPP PGAG P+PP PPPP PPPPP G G P PPP
Sbjct: 910 PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPP 969
Query: 415 LPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGL 466
LP A +P PG G + P P + PPP G+
Sbjct: 970 LPGAGIPPPPPLPGAG-------------IPPPPPLPGAGIPPPPPLPGAGI 1008
Score = 67.0 bits (162), Expect = 4e-11
Identities = 56/184 (30%), Positives = 67/184 (36%), Gaps = 50/184 (27%)
Query: 315 PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG--------------------IAPPPP 354
PPPPPS + +G+ G PP + I PPP
Sbjct: 810 PPPPPSL---------LWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPP 860
Query: 355 TP---RGPPPPGRGGPPPPPPPATGRSGP------LPPPPPGAGGPPMPPPPPPPPPPPS 405
P PG G PPPPPP G + P +P PPP G +PPPPPP P
Sbjct: 861 LPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLP---- 916
Query: 406 SGNGPAPPPLPPALVPAGG---LAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQS 462
G PP PP +P G L P G G G + P P + PPP
Sbjct: 917 ---GAGIPPPPP--LPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLP 971
Query: 463 SEGL 466
G+
Sbjct: 972 GAGI 975
Score = 60.8 bits (146), Expect = 3e-09
Identities = 53/193 (27%), Positives = 62/193 (32%), Gaps = 77/193 (39%)
Query: 349 IAPPPPTPRGPPPPGRGGP----------------------------------------- 367
I+ PPP P G+G P
Sbjct: 807 ISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTES 866
Query: 368 ----------PPPPPPATGRSGP------LPPPPPGAGGPPMPPPPPP------PPPPPS 405
PPPPPP G + P +P PPP G +PPPPPP PPPPP
Sbjct: 867 SSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL 926
Query: 406 SGNG------------PAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPES 453
G G P PPPLP A +P PG G L G + P P +
Sbjct: 927 PGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGA--GIPLPPPLPGAGIPPPPPLPGA 984
Query: 454 SALQPPPQSSEGL 466
PPP G+
Sbjct: 985 GIPPPPPLPGAGI 997
Score = 35.4 bits (80), Expect = 0.12
Identities = 52/227 (22%), Positives = 76/227 (33%), Gaps = 47/227 (20%)
Query: 265 PDLRSLFSRAGISEAQLTDAETSKLIYDF--IEDQGGL-----EAVRQEMRRQEPLPPPP 317
P + + AG + Q T + + IY F +Q L +A+R + ++Q+ L
Sbjct: 158 PIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQL 217
Query: 318 PPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG------PPPPGRGGPPPPP 371
+ QL +G P P P ++P P G P G G P P
Sbjct: 218 QQQQQQQQL---------QGAEEPAAP-PTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSP 267
Query: 372 ------------PPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLP-PA 418
P + P PP GG P+ P P P++ + P+ P P
Sbjct: 268 DTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPE 327
Query: 419 LVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
P A RGA T E A + P+ S G
Sbjct: 328 AGPGEEAAGAPVRGA-----------GDTDEEGEEDAFEDAPRGSPG 363
Score = 29.6 bits (65), Expect = 6.7
Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 13/63 (20%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
PPPP P R G+PP P PG G PP PL P + G+P P
Sbjct: 1142 PPPPLP-----RVGIPPPPPLPGA--GIPPPPPLPGAGIPPPPPLPGV------GIPPPP 1188
Query: 220 PSP 222
P P
Sbjct: 1189 PLP 1191
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 105 bits (261), Expect = 1e-22
Identities = 66/158 (41%), Positives = 71/158 (44%), Gaps = 44/158 (27%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG----IAPPPPTPRG--------- 358
P PPPPPP GG + PP + G S PP PL I PPPP P G
Sbjct: 604 PPPPPPPPLPGGVCISSPPSLPGGTAIS---PPPPLSGDATIPPPPPLPEGVGIPSPSSL 660
Query: 359 ---------PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-------PPP 402
PP PG PPPPPP G +G PPPPP G MPPPPPP PPP
Sbjct: 661 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPP 720
Query: 403 PPSSGNGPAPPPLPPAL-----------VPAGGLAPGG 429
PP G GP PP PP + VPA + P G
Sbjct: 721 PPFPG-GPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 757
Score = 105 bits (261), Expect = 1e-22
Identities = 60/125 (48%), Positives = 67/125 (53%), Gaps = 22/125 (17%)
Query: 313 LPPPPP---------PSR--GGNQLPRPPIVGGNKGRSGPLPPVP--LGIAPPPPTPRGP 359
+PPPPP PS GG +P PP + G+ P PP+P GI PPPP
Sbjct: 642 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP----- 696
Query: 360 PPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP---PPPPPSSGNGPAPPPLP 416
P PG G PPPPPP G G +PPPPP GGP +PPPPP PPPPP PA P LP
Sbjct: 697 PLPGEAGMPPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 755
Query: 417 PALVP 421
L P
Sbjct: 756 FGLTP 760
Score = 90.1 bits (222), Expect = 4e-18
Identities = 77/247 (31%), Positives = 93/247 (37%), Gaps = 72/247 (29%)
Query: 277 SEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLP---PPPPPSRGGNQLPRPPIVG 333
+E Q +AE S+L + + LE ++EM PP PSR +P P +
Sbjct: 523 TEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA--PVPPAPPLP 580
Query: 334 GNKGRSGPLPPVPL-GIAPPPPTPRGPPPPGRGG-------------------------- 366
G+ G P PP P PPPP P PPPP G
Sbjct: 581 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 640
Query: 367 ---PPPPPPPATGRSGP--------LPPPPPGAGGPPMPPPPP--------PPPPPPSSG 407
PPPP P G P +PPPPP G +PPPPP PPPPPP G
Sbjct: 641 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 700
Query: 408 NGPAPPPLPPALVPAG-GLAP----GGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQS 462
PPP PP +P G G+ P GG G P P + PPP
Sbjct: 701 EAGMPPPPPP--LPGGPGIPPPPPFPGGPG--------------IPPPPPGMGMPPPPPF 744
Query: 463 SEGLVGA 469
G+ A
Sbjct: 745 GFGVPAA 751
Score = 31.6 bits (70), Expect = 1.8
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
PPPP P + PPLP G G PP P G A + P + G+P P
Sbjct: 668 PPPPLPGSARIPPPPPPLP----GSAGIPPPPPPLPGEAGMPPPPPPLPGG--PGIPPPP 721
Query: 220 PSP 222
P P
Sbjct: 722 PFP 724
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 11/76 (14%)
Query: 153 SGDRRQLPPPPTPAN------EERRGG--LPPLPLHPGGDQGGPPVGPLSLGLATVDIQN 204
SGD PPPP P GG +PP P PG + PP PL G A +
Sbjct: 637 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-GSAGIPPPP 695
Query: 205 PDITSSRYRGLPAPGP 220
P + G+P P P
Sbjct: 696 PPLPGE--AGMPPPPP 709
Score = 30.4 bits (67), Expect = 3.9
Identities = 17/51 (33%), Positives = 20/51 (39%), Gaps = 12/51 (23%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGG--------DQGGPPVGPLSLGLATVDI 202
PPPP P G+PP P PGG G PP P G+ +
Sbjct: 707 PPPPLPGGP----GIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 753
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 105 bits (261), Expect = 1e-22
Identities = 66/158 (41%), Positives = 71/158 (44%), Gaps = 44/158 (27%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG----IAPPPPTPRG--------- 358
P PPPPPP GG + PP + G S PP PL I PPPP P G
Sbjct: 613 PPPPPPPPLPGGVCISSPPSLPGGTAIS---PPPPLSGDATIPPPPPLPEGVGIPSPSSL 669
Query: 359 ---------PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-------PPP 402
PP PG PPPPPP G +G PPPPP G MPPPPPP PPP
Sbjct: 670 PGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPP 729
Query: 403 PPSSGNGPAPPPLPPAL-----------VPAGGLAPGG 429
PP G GP PP PP + VPA + P G
Sbjct: 730 PPFPG-GPGIPPPPPGMGMPPPPPFGFGVPAAPVLPFG 766
Score = 105 bits (261), Expect = 1e-22
Identities = 60/125 (48%), Positives = 67/125 (53%), Gaps = 22/125 (17%)
Query: 313 LPPPPP---------PSR--GGNQLPRPPIVGGNKGRSGPLPPVP--LGIAPPPPTPRGP 359
+PPPPP PS GG +P PP + G+ P PP+P GI PPPP
Sbjct: 651 IPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPP----- 705
Query: 360 PPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP---PPPPPSSGNGPAPPPLP 416
P PG G PPPPPP G G +PPPPP GGP +PPPPP PPPPP PA P LP
Sbjct: 706 PLPGEAGMPPPPPPLPGGPG-IPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPVLP 764
Query: 417 PALVP 421
L P
Sbjct: 765 FGLTP 769
Score = 90.1 bits (222), Expect = 4e-18
Identities = 77/247 (31%), Positives = 93/247 (37%), Gaps = 72/247 (29%)
Query: 277 SEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLP---PPPPPSRGGNQLPRPPIVG 333
+E Q +AE S+L + + LE ++EM PP PSR +P P +
Sbjct: 532 TEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPSRA--PVPPAPPLP 589
Query: 334 GNKGRSGPLPPVPL-GIAPPPPTPRGPPPPGRGG-------------------------- 366
G+ G P PP P PPPP P PPPP G
Sbjct: 590 GDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGTAISPPPPLSGDA 649
Query: 367 ---PPPPPPPATGRSGP--------LPPPPPGAGGPPMPPPPP--------PPPPPPSSG 407
PPPP P G P +PPPPP G +PPPPP PPPPPP G
Sbjct: 650 TIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPG 709
Query: 408 NGPAPPPLPPALVPAG-GLAP----GGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQS 462
PPP PP +P G G+ P GG G P P + PPP
Sbjct: 710 EAGMPPPPPP--LPGGPGIPPPPPFPGGPG--------------IPPPPPGMGMPPPPPF 753
Query: 463 SEGLVGA 469
G+ A
Sbjct: 754 GFGVPAA 760
Score = 31.6 bits (70), Expect = 1.8
Identities = 22/63 (34%), Positives = 26/63 (41%), Gaps = 6/63 (9%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
PPPP P + PPLP G G PP P G A + P + G+P P
Sbjct: 677 PPPPLPGSARIPPPPPPLP----GSAGIPPPPPPLPGEAGMPPPPPPLPGG--PGIPPPP 730
Query: 220 PSP 222
P P
Sbjct: 731 PFP 733
Score = 30.8 bits (68), Expect = 3.0
Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 11/76 (14%)
Query: 153 SGDRRQLPPPPTPAN------EERRGG--LPPLPLHPGGDQGGPPVGPLSLGLATVDIQN 204
SGD PPPP P GG +PP P PG + PP PL G A +
Sbjct: 646 SGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLP-GSAGIPPPP 704
Query: 205 PDITSSRYRGLPAPGP 220
P + G+P P P
Sbjct: 705 PPLPGE--AGMPPPPP 718
Score = 30.4 bits (67), Expect = 3.9
Identities = 17/51 (33%), Positives = 20/51 (39%), Gaps = 12/51 (23%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGG--------DQGGPPVGPLSLGLATVDI 202
PPPP P G+PP P PGG G PP P G+ +
Sbjct: 716 PPPPLPGGP----GIPPPPPFPGGPGIPPPPPGMGMPPPPPFGFGVPAAPV 762
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 102 bits (254), Expect = 8e-22
Identities = 109/355 (30%), Positives = 127/355 (35%), Gaps = 111/355 (31%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGLPPL-PLHPGGDQGGPPVGPLSLGLATVDIQNPDIT 208
Q G++ Q PPPP P +GG P P PG QG PP G S ++P
Sbjct: 63 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS--------RSPRSP 114
Query: 209 SSRYRGLPAPG-------PSPADKKRS-----GKKKISKADIGAPSGFKHVSHVGWDPQN 256
+ +G P G P P K + G K G P G P
Sbjct: 115 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---------PPPQ 165
Query: 257 GFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPP 316
G D +S SR+ + Q QGG +P PP
Sbjct: 166 G--------DNKSRSSRSPPGKPQGPPP------------QGG----------NQPQGPP 195
Query: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAP-----------PPPTPRGPPPPGRG 365
PPP + PP GGNK + P P P G P PP P+GPPP G
Sbjct: 196 PPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 366 ---GPPPPP-----PPATGRSGPLPPPPPGAGGPPMP-----------PPPPPPPPPPSS 406
GPPPPP PP G + P PPPPG P P PP P PPP
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQG 311
Query: 407 GNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461
GN P PP PP P G GG + Q PG P+ PPPQ
Sbjct: 312 GNQPQGPPPPPG-KPQGPPPQGGNKP----------QGPPPPGKPQG----PPPQ 351
Score = 96.7 bits (239), Expect = 4e-20
Identities = 97/350 (27%), Positives = 116/350 (33%), Gaps = 121/350 (34%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGLPPL--PLHPGGDQGGPPVGPLSLGLATVDIQNPDI 207
Q G++ Q PP P P +GG P P PG QG PP G
Sbjct: 42 QGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG---------------- 85
Query: 208 TSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDL 267
++ +G P PG + K + ++ G P G PQ G
Sbjct: 86 -GNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQ--------GPPPQGG---------- 126
Query: 268 RSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLP 327
+P PPPPP +
Sbjct: 127 ------------------------------------------NQPQGPPPPPGKPQG--- 141
Query: 328 RPPIVGGNKGRSGPLPPVPLGIAP-----------PPPTPRGPPPPGRG---GPPPPP-- 371
PP GGNK + P P P G P PP P+GPPP G GPPPPP
Sbjct: 142 -PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200
Query: 372 ---PPATGRSGPLPPPPPGAGGPPMP-----------PPPPPPPPPPSSGNGPAPPPLPP 417
PP G + P PPPPG P P PP P PPP GN P PP PP
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Query: 418 AL----VPAGGLAPGG--GRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461
P GG P G G QG +++ +P PPPQ
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ 310
Score = 87.0 bits (214), Expect = 4e-17
Identities = 96/324 (29%), Positives = 114/324 (35%), Gaps = 81/324 (25%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGLPPL-PLHPGGDQGGPPVGPLSLGLATVDIQNPDIT 208
Q G++ Q PPPP P +GG P P PG QG PP G + P
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGP 183
Query: 209 SSRYRGLPAPGPSPADKKRS-----GKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNL 263
+ P P P K + G K G P G P G
Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG---------PPPQG------ 228
Query: 264 DPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP----PP 319
D +S +R+ + Q QGG + Q P PPP PP
Sbjct: 229 --DNKSQSARSPPGKPQGPPP------------QGGNQP-------QGPPPPPGKPQGPP 267
Query: 320 SRGGNQLPR----------PPIVGGNKGRSGPLPP------------VPLGIAPPPPTPR 357
+GGN+ P+ PP GG+K RS PP P G PPP P+
Sbjct: 268 PQGGNK-PQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 326
Query: 358 GPPPPGR---------GGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGN 408
GPPP G G P PPP +S PP GPP P PPP +G
Sbjct: 327 GPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG 386
Query: 409 GPAPPPLPPALVPAG-GLAPGGGR 431
P P PPA P G P GGR
Sbjct: 387 NPQQPQAPPAGQPQGPPRPPQGGR 410
Score = 83.2 bits (204), Expect = 5e-16
Identities = 63/168 (37%), Positives = 69/168 (41%), Gaps = 34/168 (20%)
Query: 318 PPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRG---GPPPPP--- 371
P GN PP GGNK P G PP P+GPPP G GPPPPP
Sbjct: 29 PSLIAGNPQGAPP-QGGNK---------PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKP 78
Query: 372 --PPATGRSGPLPPPPPG--AGGPPM--------PPPPPPPPPPPSSGNGPAPPPLPPAL 419
PP G + P PPPPG G PP PP P PPP GN P PP PP
Sbjct: 79 QGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGK 138
Query: 420 ----VPAGGLAPGG--GRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461
P GG P G G QG +++ +P PPPQ
Sbjct: 139 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQ 186
Score = 77.8 bits (190), Expect = 2e-14
Identities = 83/277 (29%), Positives = 97/277 (35%), Gaps = 61/277 (22%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGLPPL-PLHPGGDQGGPPVGPLSLGLATVDIQNPDIT 208
Q G++ Q PPPP P +GG P P PG QG PP G A P
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245
Query: 209 SSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLR 268
+ P P P K + + G P K G PQ G +
Sbjct: 246 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ---GPPPQGGS---------K 293
Query: 269 SLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPR 328
S SR+ + Q QGG +P PPPPP +
Sbjct: 294 SRSSRSPPGKPQGPPP------------QGG----------NQPQGPPPPPGKPQG---- 327
Query: 329 PPIVGGNKGRSGPLPPVPLGIAP-----------PPPTPRGPPPPGRGGPPPPPPPATGR 377
PP GGNK + P P P G P PP P+GPP P PPPPA G
Sbjct: 328 PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGG- 386
Query: 378 SGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP 414
P P P AG P PP PP G P+ PP
Sbjct: 387 -NPQQPQAPPAGQPQGPPRPP-------QGGRPSRPP 415
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 94.4 bits (233), Expect = 2e-19
Identities = 59/134 (44%), Positives = 63/134 (47%), Gaps = 16/134 (11%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPV-----PLGIAPPPPTPRGPPP--PGR 364
P PP PPP G LP PP+ G P PPV P G P P P GPPP PG
Sbjct: 247 PGPPGPPPP--GQVLP-PPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY 303
Query: 365 GGPPPPPPPATG---RSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVP 421
G PP PPPP G GP PP PPG GPP+ PPP P P G P P + PA P
Sbjct: 304 GPPPGPPPPQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFP 363
Query: 422 A---GGLAPGGGRG 432
G+ RG
Sbjct: 364 PPTNSGMPTSDSRG 377
Score = 86.7 bits (213), Expect = 5e-17
Identities = 57/121 (47%), Positives = 59/121 (48%), Gaps = 16/121 (13%)
Query: 316 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPAT 375
PPPP G PRPP+ G G GP P P G PPP PP RG PPPP
Sbjct: 226 PPPPFPAGQTPPRPPL--GPPGPPGPPGPPPPGQVLPPPLAG---PPNRGDRPPPPVLFP 280
Query: 376 GRS------GPLPP--PPPGAG-GPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLA 426
G+ GPLPP PPP G GPP PPPP PPP GP PP P L P LA
Sbjct: 281 GQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPPP--GPFPPRPPGPLGPPLTLA 338
Query: 427 P 427
P
Sbjct: 339 P 339
Score = 71.6 bits (174), Expect = 2e-12
Identities = 62/172 (36%), Positives = 65/172 (37%), Gaps = 45/172 (26%)
Query: 334 GNKGRSGPLPPVPLGIA-PPPPTPRGPPPPGRGGPPPPPPPA--TGRSGPLPPPPPG--- 387
G +GR VP G P P P GPPPP G PP PP G GP PPPPG
Sbjct: 200 GGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVL 259
Query: 388 ---AGGPP----MPPPP----------------PPPPPPPSSGNGPAP--------PPLP 416
GPP PPPP PP PPPP G GP P PP P
Sbjct: 260 PPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPPPP 319
Query: 417 PALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPE-----SSALQPPPQSS 463
P P P G G L PGAP + A PPP +S
Sbjct: 320 PGPFPP---RPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNS 368
Score = 69.7 bits (169), Expect = 6e-12
Identities = 48/114 (42%), Positives = 51/114 (44%), Gaps = 17/114 (14%)
Query: 312 PLPP-PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP-----PPGRG 365
PLPP PPPP G P PP + GP PP P P PP P GPP PP
Sbjct: 291 PLPPGPPPPVPGYGPPPGPP-----PPQQGP-PPPPGPFPPRPPGPLGPPLTLAPPPHLP 344
Query: 366 GPPP-PPPPATGRSGPLPPPPPGAGGPPM----PPPPPPPPPPPSSGNGPAPPP 414
GPPP PPPA + PPP +G P PPP P PP G PP
Sbjct: 345 GPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPP 398
Score = 48.9 bits (115), Expect = 1e-05
Identities = 44/121 (36%), Positives = 48/121 (39%), Gaps = 28/121 (23%)
Query: 312 PLPPPPPPSRG-----GNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTP------RGPP 360
P P PPPP +G G PRPP GPL P PL +APPP P PP
Sbjct: 305 PPPGPPPPQQGPPPPPGPFPPRPP---------GPLGP-PLTLAPPPHLPGPPPGA--PP 352
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
P P PPP SG P + GPP P PPP GP + A
Sbjct: 353 PAPHVNPAFFPPPT--NSG---MPTSDSRGPPPTDPYGRPPPYDRGDYGPPGREMDTART 407
Query: 421 P 421
P
Sbjct: 408 P 408
Score = 43.1 bits (100), Expect = 6e-04
Identities = 32/78 (41%), Positives = 33/78 (42%), Gaps = 11/78 (14%)
Query: 351 PPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPP---PPPPP--PPS 405
PP + R P G G P G G P P G GGPP P P PP PP PP
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPG--GDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPG 245
Query: 406 SGNGPAPPP----LPPAL 419
P PPP LPP L
Sbjct: 246 PPGPPGPPPPGQVLPPPL 263
Score = 42.0 bits (97), Expect = 0.001
Identities = 29/74 (39%), Positives = 30/74 (40%), Gaps = 8/74 (10%)
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAG---GPPMPPPPPPPPP----PPSSGNGPAPP 413
PPG P GR G P PG GP P PPPP P PP GP P
Sbjct: 188 PPGGSSRAAFPQGGRGR-GRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGP 246
Query: 414 PLPPALVPAGGLAP 427
P PP P G + P
Sbjct: 247 PGPPGPPPPGQVLP 260
Score = 34.3 bits (77), Expect = 0.27
Identities = 27/66 (40%), Positives = 29/66 (43%), Gaps = 12/66 (18%)
Query: 158 QLPPPPTPANEERRGGLPPLP-LHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLP 216
Q+ PPP A RG PP P L PG G PP+GPL G P Y P
Sbjct: 257 QVLPPPL-AGPPNRGDRPPPPVLFPGQPFGQPPLGPLPPG--------PPPPVPGYG--P 305
Query: 217 APGPSP 222
PGP P
Sbjct: 306 PPGPPP 311
Score = 29.6 bits (65), Expect = 6.7
Identities = 26/90 (28%), Positives = 28/90 (31%), Gaps = 16/90 (17%)
Query: 372 PPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV-PAGGLAPGGG 430
PP P G G P P P P+ GP PPP P P L P G
Sbjct: 188 PPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGP-PPPFPAGQTPPRPPLGPPGP 246
Query: 431 RGALLDQIRQGIQLNKTPGAPESSALQPPP 460
G PG P + PPP
Sbjct: 247 PG--------------PPGPPPPGQVLPPP 262
>gi|33356148 formin-like 1 [Homo sapiens]
Length = 1100
Score = 92.4 bits (228), Expect = 8e-19
Identities = 51/132 (38%), Positives = 59/132 (44%), Gaps = 16/132 (12%)
Query: 329 PPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPP-----------PPATGR 377
P V G P P VP G P P P PG PPPPP P A +
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564
Query: 378 SGPLPPPPPGAGGPPMP---PPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGAL 434
+ PLP P PP+P PPPPPPPPPP +GP PPP PP P GG P G
Sbjct: 565 APPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGG--PPDALGRR 622
Query: 435 LDQIRQGIQLNK 446
++ G++ K
Sbjct: 623 DSELGPGVKAKK 634
Score = 82.0 bits (201), Expect = 1e-15
Identities = 43/92 (46%), Positives = 47/92 (51%), Gaps = 10/92 (10%)
Query: 313 LPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP-PPGRGGPPPPP 371
L P P+ G P PP+ G + P P P P P +P PP PP G PPPP
Sbjct: 530 LAPAAEPAPGAAPPPPPPLPGLPSPQEAP-PSAPPQAPPLPGSPEPPPAPPLPGDLPPPP 588
Query: 372 PPATGRSGPLPPPPPGAGGPPMPPPPPPPPPP 403
PP PPPPPG GP PPPPPPPPPP
Sbjct: 589 PP--------PPPPPGTDGPVPPPPPPPPPPP 612
Score = 78.2 bits (191), Expect = 2e-14
Identities = 46/96 (47%), Positives = 49/96 (51%), Gaps = 19/96 (19%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGP--LPPVPLGIAPPPPTPRGPPPPGRGGPPPPP 371
PPPPPP G LP P S P PP+P G PPP P P P PPPPP
Sbjct: 542 PPPPPPLPG---LPSPQ----EAPPSAPPQAPPLP-GSPEPPPAP--PLPGDLPPPPPPP 591
Query: 372 PPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSG 407
PP G GP+PPPPP PPPPPP PP + G
Sbjct: 592 PPPPGTDGPVPPPPP-------PPPPPPGGPPDALG 620
Score = 73.2 bits (178), Expect = 5e-13
Identities = 41/100 (41%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 315 PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP---PPGRGGP-PPP 370
P P G P G + P PP G+ P P P PP G P PPP
Sbjct: 517 PTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPP 576
Query: 371 PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGP 410
PP G P PPPPP G P PPPPPPPPP G P
Sbjct: 577 APPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/82 (41%), Positives = 34/82 (41%), Gaps = 38/82 (46%)
Query: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPP 370
EP P PP P G LPP PPPP PPPPG GP PP
Sbjct: 573 EPPPAPPLP--------------------GDLPP-----PPPPP----PPPPGTDGPVPP 603
Query: 371 PPPATGRSGPLPPPPPGAGGPP 392
PP PPPPP GGPP
Sbjct: 604 PP---------PPPPPPPGGPP 616
Score = 31.6 bits (70), Expect = 1.8
Identities = 14/30 (46%), Positives = 15/30 (50%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPP 189
PPPP P G +PP P P GGPP
Sbjct: 587 PPPPPPPPPGTDGPVPPPPPPPPPPPGGPP 616
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 92.0 bits (227), Expect = 1e-18
Identities = 48/103 (46%), Positives = 50/103 (48%), Gaps = 17/103 (16%)
Query: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPP-PPSSGNGPAPPPLPP 417
PPPP PPPP P G P PP PP + GPP+PPPPPPPPP PP S GP PPP PP
Sbjct: 646 PPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPPPLPPPSSAGPPPPPPPP 705
Query: 418 ALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
L P P G P AP L PPP
Sbjct: 706 PL-PNSPAPPNPG---------------GPPPAPPPPGLAPPP 732
Score = 89.0 bits (219), Expect = 9e-18
Identities = 54/150 (36%), Positives = 61/150 (40%), Gaps = 16/150 (10%)
Query: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG--------PPPPGRGGPP 368
PP P+ G + LPP P I PPPP P G P PP GPP
Sbjct: 620 PPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPPVSAGPP 679
Query: 369 PPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPG 428
PPPP P P PPP + GPP PPPPPPP + P P PP P GLAP
Sbjct: 680 LPPPPPP----PPPLPPPSSAGPP----PPPPPPPLPNSPAPPNPGGPPPAPPPPGLAPP 731
Query: 429 GGRGALLDQIRQGIQLNKTPGAPESSALQP 458
G Q + P S ++P
Sbjct: 732 PPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
Score = 85.1 bits (209), Expect = 1e-16
Identities = 60/162 (37%), Positives = 78/162 (48%), Gaps = 25/162 (15%)
Query: 277 SEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEP--LPPPPP-PSRGGNQLPRPPIVG 333
S +QL+ K I+ ++ G+ + +Q+ P +PPPPP PS G+ P PP+
Sbjct: 614 SLSQLSPPNDHKDIHAALQPMEGMASNQQKALPPPPASIPPPPPLPSGLGSLSPAPPMPP 673
Query: 334 GNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRS-------GPLP-PPP 385
+ G PLPP PPPP P PPP G PPPPPPP S GP P PPP
Sbjct: 674 VSAGP--PLPP------PPPPPPPLPPPSSAGPPPPPPPPPLPNSPAPPNPGGPPPAPPP 725
Query: 386 PGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAP 427
PG PPPPP G+ + P PA+ P+ + P
Sbjct: 726 PGLA------PPPPPGLFFGLGSSSSQCPRKPAIEPSCPMKP 761
Score = 33.1 bits (74), Expect = 0.60
Identities = 24/84 (28%), Positives = 31/84 (36%), Gaps = 7/84 (8%)
Query: 141 VQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLG--LA 198
+ +Q S ++ LPPPP PPLP G PP+ P+S G L
Sbjct: 627 IHAALQPMEGMASNQQKALPPPPASIPPP-----PPLPSGLGSLSPAPPMPPVSAGPPLP 681
Query: 199 TVDIQNPDITSSRYRGLPAPGPSP 222
P + G P P P P
Sbjct: 682 PPPPPPPPLPPPSSAGPPPPPPPP 705
Score = 30.0 bits (66), Expect = 5.1
Identities = 18/40 (45%), Positives = 19/40 (47%), Gaps = 9/40 (22%)
Query: 160 PPPPTPANEERRGGLPPLPLHPG-GDQGGPPVGPLSLGLA 198
PPPP P PPLP P + GGPP P GLA
Sbjct: 698 PPPPPPP--------PPLPNSPAPPNPGGPPPAPPPPGLA 729
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 91.7 bits (226), Expect = 1e-18
Identities = 70/191 (36%), Positives = 75/191 (39%), Gaps = 56/191 (29%)
Query: 309 RQEPLPPPPPPSRGGNQLPR-----------PPIVGGNKGRSGPLPPVPLGIAP------ 351
R P P PP +GGNQ P+ PP GGN+ + P P P G P
Sbjct: 91 RSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSR 149
Query: 352 ----PPPTPRGPPPPGRG---GPPPPP-----PPATGRSGPLPPPPPG-AGGPP------ 392
PP P+GPPP G GPPPPP PP G P PPPPG GPP
Sbjct: 150 SPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKS 209
Query: 393 ---MPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPG 449
PP P PPP GN P PP PP P G GG NK G
Sbjct: 210 RSSQSPPGKPQGPPPQGGNQPQGPPPPPG-KPQGPPPQGG---------------NKPQG 253
Query: 450 APESSALQPPP 460
P Q PP
Sbjct: 254 PPPPGKPQGPP 264
Score = 91.3 bits (225), Expect = 2e-18
Identities = 72/197 (36%), Positives = 79/197 (40%), Gaps = 61/197 (30%)
Query: 314 PPPP-----PPSRGGNQLPRPPIVG--------GNKGRSGPLPP------------VPLG 348
PPPP PP +GGN+ PP G G+K RS PP P G
Sbjct: 112 PPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 171
Query: 349 IAPPPPTPRGPPPPG---RGGPPPP-----PPPATGRS--------GPLPPPPPGAGGPP 392
PPP P+GPPP G GPPPP PPP +S P PPP G P
Sbjct: 172 PPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQ 231
Query: 393 MPPPPP--PPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGA 450
PPPPP P PPP GN P PP PP P G A GG + PG
Sbjct: 232 GPPPPPGKPQGPPPQGGNKPQGPP-PPG-KPQGPPAQGGSKSQ---------SARSPPGK 280
Query: 451 PESSALQ-------PPP 460
P+ Q PPP
Sbjct: 281 PQGPPQQEGNNPQGPPP 297
Score = 84.3 bits (207), Expect = 2e-16
Identities = 71/214 (33%), Positives = 77/214 (35%), Gaps = 84/214 (39%)
Query: 314 PPPP-----PPSRGGNQLPRPPIVG--------GNKGRSGPLPP------------VPLG 348
PPPP PP +GGN+ PP G G+K RS PP P G
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG 110
Query: 349 IAPPPPTPRGPPPPGRG---GPPPP-----PPPATGRSG--------PLPPPPPGAGGPP 392
PPP P+GPPP G GPPPP PPP +S P PPP G P
Sbjct: 111 PPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ 170
Query: 393 MPPPPP------PP--------PPPPSSGNGP-----------APPPLPPALVPAGGLAP 427
PPPPP PP PPPP GP +PP P P GG P
Sbjct: 171 GPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQP 230
Query: 428 GGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQ 461
G P P PPPQ
Sbjct: 231 QG------------------PPPPPGKPQGPPPQ 246
Score = 83.2 bits (204), Expect = 5e-16
Identities = 61/167 (36%), Positives = 69/167 (41%), Gaps = 28/167 (16%)
Query: 324 NQLPRPPIVGGNKGRSGPLPP---VPLGIAPPPPTPRGPPPPGRG---GPPPP-----PP 372
+Q P ++ GN GP P P G PPP P+GPPP G GPPPP PP
Sbjct: 24 SQEESPSLIAGNP--QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
Query: 373 PATGRS--------GPLPPPPPGAGGPPMPPPPP--PPPPPPSSGN---GPAPPPLPPAL 419
P +S P PPP G P PPPPP P PPP GN GP PP P
Sbjct: 82 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
Query: 420 VPAG--GLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSE 464
P G +P G QG + P P PPPQ +
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188
Score = 81.3 bits (199), Expect = 2e-15
Identities = 95/324 (29%), Positives = 112/324 (34%), Gaps = 84/324 (25%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGLPPL-PLHPGGDQGGPPVGPLSLGLATVDIQNPDIT 208
Q G++ Q PPPP P +GG P P PG QG PP G S ++P
Sbjct: 42 QGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKS--------RSPRSP 93
Query: 209 SSRYRGLPAPG-------PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVN 261
+ +G P G P P K + + G P K G PQ
Sbjct: 94 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQ---GPPPQGDKS-- 148
Query: 262 NLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP---- 317
RS S G + QGG + Q P PPP
Sbjct: 149 ------RSPRSPPGKPQGP--------------PPQGGNQP-------QGPPPPPGKPQG 181
Query: 318 PPSRGGNQLPRPPIVG--------GNKGRSGPLPP------------VPLGIAPPPPTPR 357
PP +GG + PP G G+K RS PP P G PPP P+
Sbjct: 182 PPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 241
Query: 358 GPPPPGR---------GGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGN 408
GPPP G G P PP +S PP GPP P PPP +G
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Query: 409 GPAPPPLPPALVPAG-GLAPGGGR 431
P P PPA P G P GGR
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGR 325
Score = 79.7 bits (195), Expect = 6e-15
Identities = 95/361 (26%), Positives = 116/361 (32%), Gaps = 128/361 (35%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
P P+P + G PP PG QG PP G ++ +G P PG
Sbjct: 36 PQGPSPQGGNKPQGPPP---PPGKPQGPPPQG-----------------GNKPQGPPPPG 75
Query: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEA 279
+ K + ++ G P G PQ G P G +
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPP--------PQGGNQPQGPPPP-------PGKPQG 120
Query: 280 QLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPP-----PPPSRGGNQLPR------ 328
QGG R + PPP PPP ++ PR
Sbjct: 121 P--------------PPQGG--------NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 158
Query: 329 --PPIVGGNKGRSGPLPPVPLGIAPPPP---TPRGPPPPGRGGPPPP------------- 370
PP GGN+ + GP PP PPP P+GPPPPG+ PPP
Sbjct: 159 QGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPG 217
Query: 371 ----PPPATGRSGPLPPPPPGAGGPPMPPP----PPPPPPPPSSGNGPAP---------- 412
PPP G PPPPPG P PPP P PPPP GP
Sbjct: 218 KPQGPPPQGGNQPQGPPPPPG--KPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSAR 275
Query: 413 --------PPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSE 464
PP P G P GG + P AP + Q PP+ +
Sbjct: 276 SPPGKPQGPPQQEGNNPQGPPPPAGGN-------------PQQPQAPPAGQPQGPPRPPQ 322
Query: 465 G 465
G
Sbjct: 323 G 323
Score = 74.3 bits (181), Expect = 2e-13
Identities = 82/289 (28%), Positives = 99/289 (34%), Gaps = 70/289 (24%)
Query: 154 GDRRQLP--PPPTPANEERRGGLPPL--PLHPGGDQGGPPVGPLSLGLATVDIQNPDITS 209
GD+ + P PP P +GG P P PG QG PP G
Sbjct: 84 GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-----------------G 126
Query: 210 SRYRGLPAPG-----PSPADKKRSGKKKISKADIGAPSGFKHVSHV--------GWDPQN 256
+R +G P PG P DK RS + K P G G PQ
Sbjct: 127 NRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 186
Query: 257 GFDVNNLDPDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPP 316
G P + +++ + + K QGG +P PP
Sbjct: 187 GKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKP--QGPPPQGG----------NQPQGPP 234
Query: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG-----------IAPPPPTPRGPPPPGRG 365
PPP + PP GGNK + P P P G PP P+GPP
Sbjct: 235 PPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
Query: 366 GPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP 414
P PPPPA G P P P AG P PP PP G P+ PP
Sbjct: 291 NPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPP-------QGGRPSRPP 330
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 91.3 bits (225), Expect = 2e-18
Identities = 59/163 (36%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 307 MRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP----LGIAPPPPTPRGPPPP 362
+ +Q PPPPPP PP++ G+ P PP P +G P P PP P
Sbjct: 414 LEQQASTPPPPPP---------PPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 363 GRGGPPPP----PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
G G PP PPP G LPPPPP G PPPPPP P G G PPP PP
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP----GMGWGPPPPPPP 520
Query: 419 LVPAGGLAP--GGGRGALLDQIRQGIQLNKTPGAPESSALQPP 459
L+P P GG ++ Q+ G+ + P + PP
Sbjct: 521 LLPCTCSPPVAGGMEEVIVAQVDHGL---GSAWVPSHRRVNPP 560
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/106 (33%), Positives = 43/106 (40%), Gaps = 17/106 (16%)
Query: 327 PRPPIVGGNKGRSGPLPPVP-------LGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSG 379
P+P + G + PV L ++ P + P PPPPPPP S
Sbjct: 379 PKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTP----PPPPPPPLLPGSS 434
Query: 380 PLPPPP------PGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPAL 419
PPPP P G +P PPPPP P P PPLPP L
Sbjct: 435 AEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Score = 44.7 bits (104), Expect = 2e-04
Identities = 39/124 (31%), Positives = 45/124 (36%), Gaps = 23/124 (18%)
Query: 327 PRP-PIVGGNKGRSGPLPPVPLGIAP-----PPPTPRGPPPPGRGGPPP----------- 369
PRP P+V +K L G +P P P+ G P P
Sbjct: 348 PRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 407
Query: 370 -PPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPP----PSSGNGPAP-PPLPPALVPAG 423
P A + PPPPP P PPPPPP PS G P P PP L G
Sbjct: 408 VSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLG 467
Query: 424 GLAP 427
+AP
Sbjct: 468 AMAP 471
Score = 30.0 bits (66), Expect = 5.1
Identities = 37/148 (25%), Positives = 52/148 (35%), Gaps = 30/148 (20%)
Query: 75 VKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEA 134
VK P+ S ++ + L Q S +TP P + G A D A
Sbjct: 344 VKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKP---SVEGQQPAAAAACEPVDHA 400
Query: 135 QAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLS 194
Q+ E I K +Q ++ +++ PPP P P PL PG PP P
Sbjct: 401 QS------ESILKVSQPRALEQQASTPPPPP----------PPPLLPGSSAEPPPPPP-- 442
Query: 195 LGLATVDIQNPDITSSRYRGLPAPGPSP 222
P + S + LP P P
Sbjct: 443 ---------PPPLPSVGAKALPTAPPPP 461
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 91.3 bits (225), Expect = 2e-18
Identities = 59/163 (36%), Positives = 72/163 (44%), Gaps = 26/163 (15%)
Query: 307 MRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVP----LGIAPPPPTPRGPPPP 362
+ +Q PPPPPP PP++ G+ P PP P +G P P PP P
Sbjct: 414 LEQQASTPPPPPP---------PPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLP 464
Query: 363 GRGGPPPP----PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
G G PP PPP G LPPPPP G PPPPPP P G G PPP PP
Sbjct: 465 GLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPGLGCPPPPPPLLP----GMGWGPPPPPPP 520
Query: 419 LVPAGGLAP--GGGRGALLDQIRQGIQLNKTPGAPESSALQPP 459
L+P P GG ++ Q+ G+ + P + PP
Sbjct: 521 LLPCTCSPPVAGGMEEVIVAQVDHGL---GSAWVPSHRRVNPP 560
Score = 61.6 bits (148), Expect = 2e-09
Identities = 36/106 (33%), Positives = 43/106 (40%), Gaps = 17/106 (16%)
Query: 327 PRPPIVGGNKGRSGPLPPVP-------LGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSG 379
P+P + G + PV L ++ P + P PPPPPPP S
Sbjct: 379 PKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTP----PPPPPPPLLPGSS 434
Query: 380 PLPPPP------PGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPAL 419
PPPP P G +P PPPPP P P PPLPP L
Sbjct: 435 AEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPL 480
Score = 44.7 bits (104), Expect = 2e-04
Identities = 39/124 (31%), Positives = 45/124 (36%), Gaps = 23/124 (18%)
Query: 327 PRP-PIVGGNKGRSGPLPPVPLGIAP-----PPPTPRGPPPPGRGGPPP----------- 369
PRP P+V +K L G +P P P+ G P P
Sbjct: 348 PRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILK 407
Query: 370 -PPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPP----PSSGNGPAP-PPLPPALVPAG 423
P A + PPPPP P PPPPPP PS G P P PP L G
Sbjct: 408 VSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLG 467
Query: 424 GLAP 427
+AP
Sbjct: 468 AMAP 471
Score = 30.0 bits (66), Expect = 5.1
Identities = 37/148 (25%), Positives = 52/148 (35%), Gaps = 30/148 (20%)
Query: 75 VKDNPQKSYFIRLYGLQAGRLLWEQELYSQLVYSTPTPFFHTFAGDDCQAGLNFADEDEA 134
VK P+ S ++ + L Q S +TP P + G A D A
Sbjct: 344 VKGRPRPSPLVKAHKSVQANLDQSQRGSSPQNTTTPKP---SVEGQQPAAAAACEPVDHA 400
Query: 135 QAFRALVQEKIQKRNQRQSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLS 194
Q+ E I K +Q ++ +++ PPP P P PL PG PP P
Sbjct: 401 QS------ESILKVSQPRALEQQASTPPPPP----------PPPLLPGSSAEPPPPPP-- 442
Query: 195 LGLATVDIQNPDITSSRYRGLPAPGPSP 222
P + S + LP P P
Sbjct: 443 ---------PPPLPSVGAKALPTAPPPP 461
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 90.9 bits (224), Expect = 2e-18
Identities = 71/197 (36%), Positives = 78/197 (39%), Gaps = 60/197 (30%)
Query: 308 RRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPP-PPTPR--------- 357
R + PPPPPP G RP I R PP P PP P TPR
Sbjct: 258 RALDDKPPPPPPPVGN----RPSI-----HREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 358 GPPPPGRGGPPP-------------------------PPPPATGRSGPLPPPPPGAGGPP 392
PPPP R GPPP PP P+ GRSGPLPPPP PP
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 393 MPPPP----PPPPPPPSSGNGPAPPPLP--PALVPAGGLAPGGGRGALLDQIRQGIQLNK 446
+ PP P PPPPP S NG LP P L G +D R G +
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSG----------VDSPRSGPRPPL 418
Query: 447 TPGAPESSALQPPPQSS 463
P P + A PPP S+
Sbjct: 419 PPDRPSAGAPPPPPPST 435
Score = 90.1 bits (222), Expect = 4e-18
Identities = 82/289 (28%), Positives = 107/289 (37%), Gaps = 46/289 (15%)
Query: 156 RRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGL 215
R ++PPP + PP+P P Q P + +P + +
Sbjct: 166 RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH-----------NRGSPPVPGGPRQPS 214
Query: 216 PAPGPSPADKKRS---GKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFS 272
P P P P R G I ++ + + S F + + P D + P + +
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD-DKPPPPPPPVGN 273
Query: 273 RAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP---------PPSRGG 323
R I + R Q P PPPP PPS G
Sbjct: 274 RPSIHREAVPPPPPQN------NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 324 N-QLPRPPIVGGNKGRSGPLPPVP----LGIAPPPPTPRGPP----PPGRGGPPPPPPP- 373
N + PR P N S PP+P G PPPP+ R PP PPGR GP PPPPP
Sbjct: 328 NDETPRLP--QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 374 ----ATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
+T R+ P P P G P P PP PP + APPP PP+
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/161 (33%), Positives = 64/161 (39%), Gaps = 17/161 (10%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRS---GPLPPVPLGIAPP----PPTPRGPPPPGRGG 366
PP P R + P PP GN+G + G + PL + P PP P P
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 367 PPPPPPPATGRSG----PLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPA 422
PPPPPPP R +PPPPP PP+P P P S P PPP P P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS--SQAPPPPPPPSRPGPPPL 321
Query: 423 GGLAPGGGRGALLDQIRQGIQLNKTPGAP---ESSALQPPP 460
+ G L Q + + TP P S L PPP
Sbjct: 322 PPSSSGNDETPRLPQRNLSLS-SSTPPLPSPGRSGPLPPPP 361
Score = 70.1 bits (170), Expect = 4e-12
Identities = 59/179 (32%), Positives = 63/179 (35%), Gaps = 53/179 (29%)
Query: 316 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPAT 375
PP P R PRP + G+K S P PPVP P P P RG PP P P
Sbjct: 161 PPEPQRNRMPPPRPDV--GSKPDSIP-PPVP-----STPRPIQSSPHNRGSPPVPGGPRQ 212
Query: 376 GRSGPLPPPPPGAGG----------------------PPMPPPP------PPPPPPPSSG 407
GP PPP PG G PP+PP P PPPPPP G
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 408 NGPA------PPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
N P+ PPP P P P R P P S PPP
Sbjct: 273 NRPSIHREAVPPPPPQNNKPPVPSTP-----------RPSASSQAPPPPPPPSRPGPPP 320
Score = 62.0 bits (149), Expect = 1e-09
Identities = 83/310 (26%), Positives = 110/310 (35%), Gaps = 63/310 (20%)
Query: 154 GDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYR 213
G RQ P PTP PP P + G GG + L ++ P + + R
Sbjct: 208 GGPRQPSPGPTP---------PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 214 GL---PAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSL 270
L P P P P + S I + + P + V P+ ++ P
Sbjct: 259 ALDDKPPPPPPPVGNRPS----IHREAVPPPPPQNNKPPVPSTPRPS--ASSQAPPPPPP 312
Query: 271 FSRAG---ISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP---------- 317
SR G + + + ET +L + + R PLPPPP
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP-GRSGPLPPPPSERPPPPVRD 371
Query: 318 PPSRGGNQLPRPPIVGGNKGRSGPLPPVP-----LGIAPPPPTPRGPPPPGR---GGPPP 369
PP R G LP PP V N S LP P G+ P PR P PP R G PPP
Sbjct: 372 PPGRSG-PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Query: 370 PPPPATGRSGPLPPPPPGAGGP-----PMPPPPPPPPPPPSSGNGPA------------- 411
PPP + R+G P P+ PPP P ++ + P+
Sbjct: 431 PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNR 490
Query: 412 ----PPPLPP 417
PPLPP
Sbjct: 491 RERGAPPLPP 500
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/149 (32%), Positives = 58/149 (38%), Gaps = 23/149 (15%)
Query: 328 RPPIV--GGNKGRSGPLPPVPLGIAPPPPTP---RGPPPPGRGGPPPPPPPATGRSGPLP 382
RPP++ GG + P P P P+P GPP P R PPP P + +P
Sbjct: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 383 PPPPGAGGPPMPPP-----PPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQ 437
PP P P P PP P P GP PPP P G A GGG
Sbjct: 185 PPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFP----GNRGTALGGG------S 234
Query: 438 IRQGIQLNKTPGAPESSALQPPPQSSEGL 466
IRQ + +P S+ PP S L
Sbjct: 235 IRQS---PLSSSSPFSNRPPLPPTPSRAL 260
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 15/67 (22%)
Query: 365 GGPPPPPPPATGRS------------GPLPPPPPG-AGGPPMPPPPPPPPPPPSSGNGP- 410
GG PP P GRS G P P PG GPP P PPP P G+ P
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 411 -APPPLP 416
PPP+P
Sbjct: 182 SIPPPVP 188
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 392 PMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAP 451
P+PPPP PPPPP + P L GR ALL I +G +L KT
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTL--------NKTEQAGRNALLSDISKGKKLKKTVTND 53
Query: 452 ESSALQPPPQSS 463
S+ + P+ +
Sbjct: 54 RSAPILDKPKGA 65
Score = 37.0 bits (84), Expect = 0.042
Identities = 55/226 (24%), Positives = 75/226 (33%), Gaps = 65/226 (28%)
Query: 158 QLPPPPTPANEERRGGLPPLPLHPGGDQGGP--PVGPLSLGLATVDIQN----------- 204
Q PPPP P + R G PPLP G+ P P LSL +T + +
Sbjct: 305 QAPPPPPPPS---RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
Query: 205 -----PDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFD 259
P + R P P P P + S + + P+ + S G D
Sbjct: 362 SERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL-------PATPQLPSRSGVDSPRSGP 414
Query: 260 VNNLDPDLRSLFS----------RAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRR 309
L PD S + R G ++ D S+ + I D
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISD------------- 461
Query: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSG---------PLPPVP 346
LPPP P + P + N+ RSG PLPP+P
Sbjct: 462 ---LPPPEPYVQTTKSYPSK--LARNESRSGSNRRERGAPPLPPIP 502
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 90.9 bits (224), Expect = 2e-18
Identities = 71/197 (36%), Positives = 78/197 (39%), Gaps = 60/197 (30%)
Query: 308 RRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPP-PPTPR--------- 357
R + PPPPPP G RP I R PP P PP P TPR
Sbjct: 258 RALDDKPPPPPPPVGN----RPSI-----HREAVPPPPPQNNKPPVPSTPRPSASSQAPP 308
Query: 358 GPPPPGRGGPPP-------------------------PPPPATGRSGPLPPPPPGAGGPP 392
PPPP R GPPP PP P+ GRSGPLPPPP PP
Sbjct: 309 PPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPP 368
Query: 393 MPPPP----PPPPPPPSSGNGPAPPPLP--PALVPAGGLAPGGGRGALLDQIRQGIQLNK 446
+ PP P PPPPP S NG LP P L G +D R G +
Sbjct: 369 VRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSG----------VDSPRSGPRPPL 418
Query: 447 TPGAPESSALQPPPQSS 463
P P + A PPP S+
Sbjct: 419 PPDRPSAGAPPPPPPST 435
Score = 90.1 bits (222), Expect = 4e-18
Identities = 82/289 (28%), Positives = 107/289 (37%), Gaps = 46/289 (15%)
Query: 156 RRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGL 215
R ++PPP + PP+P P Q P + +P + +
Sbjct: 166 RNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH-----------NRGSPPVPGGPRQPS 214
Query: 216 PAPGPSPADKKRS---GKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFS 272
P P P P R G I ++ + + S F + + P D + P + +
Sbjct: 215 PGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALD-DKPPPPPPPVGN 273
Query: 273 RAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP---------PPSRGG 323
R I + R Q P PPPP PPS G
Sbjct: 274 RPSIHREAVPPPPPQN------NKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSG 327
Query: 324 N-QLPRPPIVGGNKGRSGPLPPVP----LGIAPPPPTPRGPP----PPGRGGPPPPPPP- 373
N + PR P N S PP+P G PPPP+ R PP PPGR GP PPPPP
Sbjct: 328 NDETPRLP--QRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPV 385
Query: 374 ----ATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
+T R+ P P P G P P PP PP + APPP PP+
Sbjct: 386 SRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPS 434
Score = 71.2 bits (173), Expect = 2e-12
Identities = 54/161 (33%), Positives = 64/161 (39%), Gaps = 17/161 (10%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRS---GPLPPVPLGIAPP----PPTPRGPPPPGRGG 366
PP P R + P PP GN+G + G + PL + P PP P P
Sbjct: 204 PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDK 263
Query: 367 PPPPPPPATGRSG----PLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPA 422
PPPPPPP R +PPPPP PP+P P P S P PPP P P
Sbjct: 264 PPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSAS--SQAPPPPPPPSRPGPPPL 321
Query: 423 GGLAPGGGRGALLDQIRQGIQLNKTPGAP---ESSALQPPP 460
+ G L Q + + TP P S L PPP
Sbjct: 322 PPSSSGNDETPRLPQRNLSLS-SSTPPLPSPGRSGPLPPPP 361
Score = 70.1 bits (170), Expect = 4e-12
Identities = 59/179 (32%), Positives = 63/179 (35%), Gaps = 53/179 (29%)
Query: 316 PPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPAT 375
PP P R PRP + G+K S P PPVP P P P RG PP P P
Sbjct: 161 PPEPQRNRMPPPRPDV--GSKPDSIP-PPVP-----STPRPIQSSPHNRGSPPVPGGPRQ 212
Query: 376 GRSGPLPPPPPGAGG----------------------PPMPPPP------PPPPPPPSSG 407
GP PPP PG G PP+PP P PPPPPP G
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVG 272
Query: 408 NGPA------PPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPP 460
N P+ PPP P P P R P P S PPP
Sbjct: 273 NRPSIHREAVPPPPPQNNKPPVPSTP-----------RPSASSQAPPPPPPPSRPGPPP 320
Score = 62.0 bits (149), Expect = 1e-09
Identities = 83/310 (26%), Positives = 110/310 (35%), Gaps = 63/310 (20%)
Query: 154 GDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYR 213
G RQ P PTP PP P + G GG + L ++ P + + R
Sbjct: 208 GGPRQPSPGPTP---------PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSR 258
Query: 214 GL---PAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSL 270
L P P P P + S I + + P + V P+ ++ P
Sbjct: 259 ALDDKPPPPPPPVGNRPS----IHREAVPPPPPQNNKPPVPSTPRPS--ASSQAPPPPPP 312
Query: 271 FSRAG---ISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPP---------- 317
SR G + + + ET +L + + R PLPPPP
Sbjct: 313 PSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSP-GRSGPLPPPPSERPPPPVRD 371
Query: 318 PPSRGGNQLPRPPIVGGNKGRSGPLPPVP-----LGIAPPPPTPRGPPPPGR---GGPPP 369
PP R G LP PP V N S LP P G+ P PR P PP R G PPP
Sbjct: 372 PPGRSG-PLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPP 430
Query: 370 PPPPATGRSGPLPPPPPGAGGP-----PMPPPPPPPPPPPSSGNGPA------------- 411
PPP + R+G P P+ PPP P ++ + P+
Sbjct: 431 PPPSTSIRNGFQDSPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKLARNESRSGSNR 490
Query: 412 ----PPPLPP 417
PPLPP
Sbjct: 491 RERGAPPLPP 500
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/149 (32%), Positives = 58/149 (38%), Gaps = 23/149 (15%)
Query: 328 RPPIV--GGNKGRSGPLPPVPLGIAPPPPTP---RGPPPPGRGGPPPPPPPATGRSGPLP 382
RPP++ GG + P P P P+P GPP P R PPP P + +P
Sbjct: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184
Query: 383 PPPPGAGGPPMPPP-----PPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQ 437
PP P P P PP P P GP PPP P G A GGG
Sbjct: 185 PPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFP----GNRGTALGGG------S 234
Query: 438 IRQGIQLNKTPGAPESSALQPPPQSSEGL 466
IRQ + +P S+ PP S L
Sbjct: 235 IRQS---PLSSSSPFSNRPPLPPTPSRAL 260
Score = 41.2 bits (95), Expect = 0.002
Identities = 27/67 (40%), Positives = 29/67 (43%), Gaps = 15/67 (22%)
Query: 365 GGPPPPPPPATGRS------------GPLPPPPPG-AGGPPMPPPPPPPPPPPSSGNGP- 410
GG PP P GRS G P P PG GPP P PPP P G+ P
Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPD 181
Query: 411 -APPPLP 416
PPP+P
Sbjct: 182 SIPPPVP 188
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 392 PMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAP 451
P+PPPP PPPPP + P L GR ALL I +G +L KT
Sbjct: 2 PVPPPPAPPPPPTFALANTEKPTL--------NKTEQAGRNALLSDISKGKKLKKTVTND 53
Query: 452 ESSALQPPPQSS 463
S+ + P+ +
Sbjct: 54 RSAPILDKPKGA 65
Score = 37.0 bits (84), Expect = 0.042
Identities = 55/226 (24%), Positives = 75/226 (33%), Gaps = 65/226 (28%)
Query: 158 QLPPPPTPANEERRGGLPPLPLHPGGDQGGP--PVGPLSLGLATVDIQN----------- 204
Q PPPP P + R G PPLP G+ P P LSL +T + +
Sbjct: 305 QAPPPPPPPS---RPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
Query: 205 -----PDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFD 259
P + R P P P P + S + + P+ + S G D
Sbjct: 362 SERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRAL-------PATPQLPSRSGVDSPRSGP 414
Query: 260 VNNLDPDLRSLFS----------RAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRR 309
L PD S + R G ++ D S+ + I D
Sbjct: 415 RPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCEDEWESRFYFHPISD------------- 461
Query: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSG---------PLPPVP 346
LPPP P + P + N+ RSG PLPP+P
Sbjct: 462 ---LPPPEPYVQTTKSYPSK--LARNESRSGSNRRERGAPPLPPIP 502
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 89.0 bits (219), Expect = 9e-18
Identities = 55/134 (41%), Positives = 67/134 (50%), Gaps = 10/134 (7%)
Query: 299 GLEAVRQEMRRQEPLPPPPPPSRGGN-QLPRPPIVGGNKGRSGPLPPVPLGIAPP---PP 354
G ++++ M+ + P PP+ G LP P V P+PP P PP PP
Sbjct: 443 GYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPP 502
Query: 355 TPRGPPPPGRGGPP-PPPPPATGRSGPLPP-PPPGAGGPPMPPPPPPPPPPPSSGNGPAP 412
TP PPPP P PPPPP + +PP PPPG G PP PPP PP G P P
Sbjct: 503 TPGYPPPPPTYNPNFPPPPPRLPPTHAVPPHPPPGLGLPPASYPPPAVPP---GGQPPVP 559
Query: 413 PPL-PPALVPAGGL 425
PP+ PP + P GGL
Sbjct: 560 PPIPPPGMPPVGGL 573
Score = 78.2 bits (191), Expect = 2e-14
Identities = 49/108 (45%), Positives = 50/108 (46%), Gaps = 19/108 (17%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPT--PRGPPPPGRGGP-- 367
P PPPPP P P I PP P G PPPPT P PPPP R P
Sbjct: 480 PNPPPPPVPPPPASFPPPAIP----------PPTP-GYPPPPPTYNPNFPPPPPRLPPTH 528
Query: 368 --PPPPPPATGRSGPLPPPP--PGAGGPPMPPPPPPPPPPPSSGNGPA 411
PP PPP G PPP P G PP+PPP PPP PP G G A
Sbjct: 529 AVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPPVGGLGRA 576
Score = 77.4 bits (189), Expect = 3e-14
Identities = 53/140 (37%), Positives = 59/140 (42%), Gaps = 29/140 (20%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRS-------------GPLPPVPLGIAPPPPTPRGPP 360
PPPPPPS + +G G LPP PP P P
Sbjct: 420 PPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPA---YGPPAHLPYHPH 476
Query: 361 --PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPP------PPPPPPPPPSSGNGPAP 412
PP PP PPPPA+ +PPP PG PP PP PPPPP PP+ P P
Sbjct: 477 VYPPNPPPPPVPPPPASFPPPAIPPPTPGY--PPPPPTYNPNFPPPPPRLPPTHAVPPHP 534
Query: 413 PP---LPPALVPAGGLAPGG 429
PP LPPA P + PGG
Sbjct: 535 PPGLGLPPASYPPPAVPPGG 554
Score = 63.2 bits (152), Expect = 5e-10
Identities = 57/176 (32%), Positives = 64/176 (36%), Gaps = 67/176 (38%)
Query: 312 PLPPP-PPPSRGGNQLPRPPIVGGNKGRSGPLPPV-----PLGIAPPP----PTPRGPPP 361
PLPP PPP R +PP+ G + P PV P PPP P + PP
Sbjct: 364 PLPPAHPPPDR------KPPLAAA-LGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL 416
Query: 362 PGRGGPPPPPPPATGRS-------------------------GPLPPP------------ 384
P R PPPP TG S G LPP
Sbjct: 417 PHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPH 476
Query: 385 --PPGAGGPPMPPP----PPPPPPPPSSGNGPAP-------PPLPPALVPAGGLAP 427
PP PP+PPP PPP PPP+ G P P PP PP L P + P
Sbjct: 477 VYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPTHAVPP 532
Score = 58.2 bits (139), Expect = 2e-08
Identities = 42/122 (34%), Positives = 50/122 (40%), Gaps = 20/122 (16%)
Query: 301 EAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGG---NKGRSGPLPPVPLGIAPPPPTPR 357
+ +Q+ Q+P P P PS Q+ R +V NK P P +P PP P
Sbjct: 309 QPAQQQQPAQQPKKPSPQPS-SPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPP 367
Query: 358 GPPPPGRGGPPPPPPPATGRSGPLPP-----------PPPGAGGPPMPPPPPP--PPPPP 404
PPP R PP A G + P P PPP P PPP P PPPPP
Sbjct: 368 AHPPPDR---KPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPP 424
Query: 405 SS 406
S
Sbjct: 425 PS 426
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/131 (28%), Positives = 47/131 (35%), Gaps = 20/131 (15%)
Query: 304 RQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP-- 361
+Q+M P PPS P+ P V ++ P P P P + P
Sbjct: 262 KQQMPHHTPHQLQQPPSL--QPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQ 319
Query: 362 PGRGGPPPPPP----------PATGRSGPLPPPPP----GAGGPPMPP--PPPPPPPPPS 405
P + P P P P PPPP PP+PP PPP PP +
Sbjct: 320 PKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDRKPPLA 379
Query: 406 SGNGPAPPPLP 416
+ G A PP P
Sbjct: 380 AALGEAEPPGP 390
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 88.2 bits (217), Expect = 2e-17
Identities = 57/141 (40%), Positives = 64/141 (45%), Gaps = 16/141 (11%)
Query: 305 QEMRRQEPLP--PPPPPSRGGNQLPRPPIVGGNKG--RSGPLPPVPLGIAPP-------- 352
Q+ Q+P P PPP P Q P PP +K GP P +G APP
Sbjct: 75 QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPA 134
Query: 353 -PPTPRGPPPPGRGGPPPPPPPATGRSGPLPPP-PPGAGGPPMPPPPPPPPPPPSS--GN 408
PPT PP G G P PPP T PPP PP +G P PP PPPPP++ G
Sbjct: 135 TPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194
Query: 409 GPAPPPLPPALVPAGGLAPGG 429
GP P P P GG PGG
Sbjct: 195 GPGPKQGPGPGGPKGGKMPGG 215
Score = 86.3 bits (212), Expect = 6e-17
Identities = 68/195 (34%), Positives = 78/195 (40%), Gaps = 70/195 (35%)
Query: 317 PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP------PTPRGPPPPG------- 363
PPP G NQ P +G G+SGP PP+P PPP P P+ PPP
Sbjct: 34 PPPGMGLNQNRGP--MGPGPGQSGPKPPIP---PPPPHQQQQQPPPQQPPPQQPPPHQPP 88
Query: 364 -------RGGPPPPP---------------------PPATGRSGPLPPP----PPGAGGP 391
+ PPPPP PPA+ + P PP PPG+G
Sbjct: 89 PHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPG 148
Query: 392 PMPPPPP---------PPPPPPSSGNGPAP-----PPLPPALVPAGGLAPGGGRGALLDQ 437
P P PPP PPP PPSSG P PP PPA VP G P G G
Sbjct: 149 PTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGP---- 204
Query: 438 IRQGIQLNKTPGAPE 452
G + K PG P+
Sbjct: 205 --GGPKGGKMPGGPK 217
Score = 67.8 bits (164), Expect = 2e-11
Identities = 55/157 (35%), Positives = 62/157 (39%), Gaps = 33/157 (21%)
Query: 305 QEMRRQEPLPPP-----------PPPSRGGNQLP---------RPPIVGGNKGRSG---P 341
Q ++Q+P PPP P P+ G P PP G G P
Sbjct: 92 QPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTP 151
Query: 342 LPPVPLGIAPP---PPTPRG---PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPP 395
PP + APP PPTP P P + G PPPPP A GP P PG GGP
Sbjct: 152 TPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGK 211
Query: 396 PPPPPPPPPSSG-NGPAPPPLPPALVPAGGLAPGGGR 431
P P P G + P P PP GG P GGR
Sbjct: 212 MPGGPKPGGGPGLSTPGGHPKPP---HRGGGEPRGGR 245
Score = 54.3 bits (129), Expect = 3e-07
Identities = 38/106 (35%), Positives = 41/106 (38%), Gaps = 16/106 (15%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGR-------GG 366
PPP PPS G +P P G GP PP P + P P P+ P PG GG
Sbjct: 165 PPPTPPSSG---VPTTPPQAG-----GP-PPPPAAVPGPGPGPKQGPGPGGPKGGKMPGG 215
Query: 367 PPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAP 412
P P P G P PP GG P PP GP P
Sbjct: 216 PKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPP 261
Score = 45.8 bits (107), Expect = 9e-05
Identities = 70/251 (27%), Positives = 79/251 (31%), Gaps = 52/251 (20%)
Query: 152 QSGDRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSR 211
QSG + +PPPP +++ P P P Q P P Q P
Sbjct: 53 QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQ------QQQPPPPPQDS 106
Query: 212 YRGLPAPGPSPADKKRSGKKKISKADIGAP--SGFKHVSHVGWDPQNGFDVNNLDPDLRS 269
+ + A GP PA S S A P SG S G P V + P
Sbjct: 107 SKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPP 166
Query: 270 LFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPP-----PSRGGN 324
S + GG PPPPP P G
Sbjct: 167 -------------PTPPSSGVPTTPPQAGG--------------PPPPPAAVPGPGPGPK 199
Query: 325 QLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG-PPPPGRGGPPP-------PPPPATG 376
Q P P GG KG P P P G P TP G P PP RGG P PP
Sbjct: 200 QGPGP---GGPKGGKMPGGPKPGG-GPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQH 255
Query: 377 RSGPLPPPPPG 387
GP P P G
Sbjct: 256 HQGPPPGGPGG 266
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 87.0 bits (214), Expect = 4e-17
Identities = 52/119 (43%), Positives = 57/119 (47%), Gaps = 23/119 (19%)
Query: 312 PLPPPPP--PSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPP 369
P PPP P PS N P PP++ PP P PP PTP+ PPP PPP
Sbjct: 1431 PGPPPLPGLPSANSNGTPEPPLLEEKP------PPTP----PPAPTPQPQPPP----PPP 1476
Query: 370 PPPPATGRSGPL-------PPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVP 421
PP PA PL PPPPP PP P PPPPPPP++ APP P A P
Sbjct: 1477 PPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSP 1535
Score = 74.3 bits (181), Expect = 2e-13
Identities = 49/118 (41%), Positives = 52/118 (44%), Gaps = 25/118 (21%)
Query: 315 PPPPPSRGGNQLPRPPIVGG-NKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPP 373
P PP +P PP + G S P PL PPPTP PP P P P PPP
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTP--PPAPT---PQPQPPP 1473
Query: 374 ATGRSGPLPPPPPG----------AGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVP 421
PPPPP A P PPPPP PPPPP + P PPP PPA P
Sbjct: 1474 --------PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPP-PPAAAP 1522
Score = 73.2 bits (178), Expect = 5e-13
Identities = 60/189 (31%), Positives = 73/189 (38%), Gaps = 26/189 (13%)
Query: 326 LPRPPIVGGNKGRSGPLPPV-PLGIAP-PPPTPRGPPPPGRGGP--------PPPPPPAT 375
L PP+ G + PP+ P P PPP P P G P PPP PP
Sbjct: 1405 LDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPA 1464
Query: 376 GRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALL 435
P PPPPP P +P PPP P PSS P PPPLPP PA P A
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSS---PPPPPLPPPPPPAMPSPPPPPPPAAA 1521
Query: 436 DQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSRA--IHSSDEGEDQAGD 493
AP P P+ E +H+ +K+ A +DE ++G
Sbjct: 1522 PL-----------AAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCGETDEEAGESGG 1570
Query: 494 EDEDDEWDD 502
E E D+
Sbjct: 1571 EGIFRERDE 1579
Score = 72.8 bits (177), Expect = 7e-13
Identities = 57/166 (34%), Positives = 66/166 (39%), Gaps = 27/166 (16%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPP 373
PPPPPP+ Q P G +G P +PL + PPPP P P P P
Sbjct: 764 PPPPPPTAQSTQ----PTPHGLLLEAGG-PDLPLVLPPPPPQLL----PSVLSHAPSPSP 814
Query: 374 ATGRSGPLPPPPPGAGGPPMPPPPPPPPPPP----------SSGNGPAPPPLPPALVPAG 423
+ + G P G P PPPPPPPPPPP S G PA P P L P
Sbjct: 815 SASKVGVHLLEPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAP--SPRLRPEE 872
Query: 424 GLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGA 469
L P G LL L P AP + + PP + GA
Sbjct: 873 SLDPPGAMQELLG------ALEPLPPAPGDTGVGPPNSEGKDPAGA 912
Score = 70.9 bits (172), Expect = 3e-12
Identities = 48/121 (39%), Positives = 53/121 (43%), Gaps = 43/121 (35%)
Query: 307 MRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGG 366
+ + P PPP P+ P+PP PP PPPP P P PP
Sbjct: 1453 LEEKPPPTPPPAPT----PQPQPP------------PP------PPPPQPALPSPPPLVA 1490
Query: 367 PPP--PPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPP-------PPSSGNGPAP--PPL 415
P P PPPP PLPPPPP P MP PPPPPPP PP P+P P L
Sbjct: 1491 PTPSSPPPP------PLPPPPP----PAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Query: 416 P 416
P
Sbjct: 1541 P 1541
Score = 62.4 bits (150), Expect = 9e-10
Identities = 34/92 (36%), Positives = 37/92 (40%)
Query: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPP 369
+E PP PPP+ P PP P P V + PPP P PPPP PP
Sbjct: 1454 EEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPP 1513
Query: 370 PPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401
PPPP PP P A P P P P
Sbjct: 1514 PPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545
Score = 55.1 bits (131), Expect = 1e-07
Identities = 38/107 (35%), Positives = 39/107 (36%), Gaps = 25/107 (23%)
Query: 329 PPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGA 388
P G K +GP P PP P GP PGR P P G PP P
Sbjct: 968 PEDEGDPKAGAGPPP------GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPST 1021
Query: 389 ----------GGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGL 425
GP PPPPPPPPP P PA P GGL
Sbjct: 1022 VNAEPLGLIQSGPHQAAPPPPPPPPP---------PPAPASEPKGGL 1059
Score = 54.3 bits (129), Expect = 3e-07
Identities = 60/227 (26%), Positives = 71/227 (31%), Gaps = 87/227 (38%)
Query: 299 GLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPL---------GI 349
G+ + R P PPPPPP P PP+PL G+
Sbjct: 820 GVHLLEPATRDGAPQPPPPPPP--------------------PPPPMPLQLEAHLRSHGL 859
Query: 350 APPPPTPRGPP-----PPGRG----GPPPPPPPATGRSGPLPP-----PPPGAGGPPMPP 395
P P+PR P PPG G P PPA G +G PP P GA P P
Sbjct: 860 EPAAPSPRLRPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQ 919
Query: 396 PPPPPP-----------------------------------------PPPSSGN---GPA 411
P PP G+ G
Sbjct: 920 GTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAG 979
Query: 412 PPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQP 458
PPP PPA P G PG GA + G+ NK P P + +P
Sbjct: 980 PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP 1026
Score = 49.7 bits (117), Expect = 6e-06
Identities = 36/94 (38%), Positives = 37/94 (39%), Gaps = 18/94 (19%)
Query: 353 PPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPP---PPPPPPPPPSSGN- 408
PP G P G G PPP PPA GP P GP P P PP PS+ N
Sbjct: 967 PPEDEGDPKAGAG--PPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNA 1024
Query: 409 --------GP----APPPLPPALVPAGGLAPGGG 430
GP PPP PP PA P GG
Sbjct: 1025 EPLGLIQSGPHQAAPPPPPPPPPPPAPASEPKGG 1058
Score = 48.9 bits (115), Expect = 1e-05
Identities = 54/195 (27%), Positives = 61/195 (31%), Gaps = 31/195 (15%)
Query: 299 GLEAVRQEMRRQEPLPPPPPPSRGGNQ---LPRPPIVGGNKGRSGPLPPVPLGIAPPPPT 355
GL + R P PPPPP Q L +S P G AP PP
Sbjct: 218 GLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPP 277
Query: 356 PRGPPP-----------PGRGGPPPPPPPA---------------TGRSGPLPPPPPGAG 389
P P P PPPPPPPA G L P G G
Sbjct: 278 PERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGG 337
Query: 390 GPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTP- 448
P P P + G + P GG GGG + Q G + K
Sbjct: 338 EPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQ-SPGYKTGKGGY 396
Query: 449 GAPESSALQPPPQSS 463
GA A +PPP S
Sbjct: 397 GAAAGGATRPPPPRS 411
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/183 (30%), Positives = 61/183 (33%), Gaps = 42/183 (22%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP------PTPRGPP--PPGRG 365
PP PP+ G L P V K P P LG P GP PP R
Sbjct: 173 PPFSPPANG---LLSPHDVLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRP 229
Query: 366 GPPPPPPP-----------------ATGRSGPLPPPPPGAGGPPMPPPPPPPPP------ 402
GPP PPPP A P +G P PPPP P
Sbjct: 230 GPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVI 289
Query: 403 ----PPSSGNGPAPPPLPPAL---VPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSA 455
P+S P PPP AL + GG P G A L G +PGA E S
Sbjct: 290 KHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLG-GGEPSPGAGEPSK 348
Query: 456 LQP 458
P
Sbjct: 349 AGP 351
Score = 40.8 bits (94), Expect = 0.003
Identities = 54/218 (24%), Positives = 68/218 (31%), Gaps = 65/218 (29%)
Query: 333 GGNKGRSGPLPPVPLGIAPPPPTPRGPPPPG-------------------RGGPPPPP-- 371
G G++ L P PP P GPPPPG +G P P P
Sbjct: 460 GFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAA 519
Query: 372 -------------------PPATGRSGPLPPPPPGAGGPPMP-------PPPPPPPPPPS 405
P +G G P G GG P PP PP
Sbjct: 520 HSQGLPTASPSLSYSTGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPPATGRPPG 579
Query: 406 SGNGPAPPPL-------PPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQP 458
G+ AP P L P G + G G + G +L PG P
Sbjct: 580 VGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGK-GDGSELLAGPGG-------P 631
Query: 459 PPQSSEGLVGALMHVMQKRSRAIHSSDE---GEDQAGD 493
P + +E + H++Q S S + GED A D
Sbjct: 632 PAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAAD 669
Score = 40.8 bits (94), Expect = 0.003
Identities = 33/115 (28%), Positives = 39/115 (33%), Gaps = 26/115 (22%)
Query: 288 KLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPL 347
+L F+E+ + VR R+ P PP P R Q P GG+
Sbjct: 1644 RLYVKFLENVNKKDYVRVCARK--PWHRPPVPVRRSGQAKNPVSAGGSS----------- 1690
Query: 348 GIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPP 402
APPP P PPP P T PP MP PP P P
Sbjct: 1691 --APPPKAPA-----------PPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP 1732
Score = 39.3 bits (90), Expect = 0.008
Identities = 65/247 (26%), Positives = 85/247 (34%), Gaps = 66/247 (26%)
Query: 274 AGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPL------------PPPPPPSR 321
A S A ++S +Y+F G + + RQ+ + PPPPPP+
Sbjct: 249 ASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAH 308
Query: 322 GGNQLPRPPIVGGN---KGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRS 378
L GG+ G L PLG P P G P + GP A+GR+
Sbjct: 309 A---LQHYLSCGGSYPSMGHRANLACSPLGGGEPSP---GAGEPSKAGPSGATAGASGRA 362
Query: 379 -GPLPPPPPGAGG------PPMPPP---------------PPPPPPPPSSG-------NG 409
GP GAGG P + P PPPP S+ G
Sbjct: 363 TGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGG 422
Query: 410 PAPPPLPPALVPAGG-----LAPGGGRGALLDQI-------RQGIQLNKTP----GAPES 453
PA AGG +PG +G L Q Q L+K P G P+
Sbjct: 423 PAAAYATGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQP 482
Query: 454 SALQPPP 460
+ PPP
Sbjct: 483 PSGPPPP 489
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/56 (41%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 377 RSGPLPPPPPGAG-GPPMPPPPPPPPPPPSSGNGPAPPPLP--PALVPAGGLAPGG 429
+SG PP AG PP+ PP PP P+ G P PP P P P+G GG
Sbjct: 1290 KSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGG 1345
Score = 36.2 bits (82), Expect = 0.071
Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 6/54 (11%)
Query: 357 RGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPP-PPPPPSSGNG 409
R PP G PP PP + +PP P G P PP P P PPPS G
Sbjct: 1294 RHPPLYQAGLTPPLSPPKS-----VPPSVPARGLQPQPPATPAVPHPPPSGAFG 1342
Score = 35.4 bits (80), Expect = 0.12
Identities = 61/248 (24%), Positives = 79/248 (31%), Gaps = 54/248 (21%)
Query: 154 GDRRQLPPPPTPANEERRGGLPPLPLHPGGDQ--GGPPVGPLSL----GLATVDIQNPDI 207
GD PP P P RRG P G + G P + PL + G A+
Sbjct: 1138 GDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGA 1197
Query: 208 TSSRYRGLPAPGPSP-ADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPD 266
R RG + A R K K + P + + D +G D N+LD
Sbjct: 1198 KKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSS 1257
Query: 267 LRSLFSRAGISEAQLTDAET-SKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQ 325
L A I E + E S + F++ + G +
Sbjct: 1258 LTREKIEAKIKEVEEKQPEMKSGFMASFLDFL-----------------------KSGKR 1294
Query: 326 LPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP--PGRG-GPPPPPPPATGRSGPLP 382
P P G+ PP P+ PP P RG P PP PA
Sbjct: 1295 HP---------------PLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPH----- 1334
Query: 383 PPPPGAGG 390
PPP GA G
Sbjct: 1335 PPPSGAFG 1342
Score = 35.4 bits (80), Expect = 0.12
Identities = 23/70 (32%), Positives = 26/70 (37%), Gaps = 3/70 (4%)
Query: 354 PTPRGPPPPGRGGPPPPPPPATGRSGPL---PPPPPGAGGPPMPPPPPPPPPPPSSGNGP 410
P R P P R G P A G S P P PPP P PP P +
Sbjct: 1666 PWHRPPVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPE 1725
Query: 411 APPPLPPALV 420
P P P+L+
Sbjct: 1726 PPAPEKPSLL 1735
Score = 32.7 bits (73), Expect = 0.79
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 17/104 (16%)
Query: 329 PPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGA 388
P +V + R P + PP P P GP GR P R G PP P G
Sbjct: 1122 PDLVSSCRSRPALSPLGDIDFCPPNPGPDGPRRRGR------KPTKAKRDG--PPRPRGR 1173
Query: 389 GGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRG 432
P P P ++G A P A P G G GRG
Sbjct: 1174 ------PRIRPLEVPTTAGPASASTPTDGAKKPRG---RGRGRG 1208
>gi|13699803 WAS protein family, member 3 [Homo sapiens]
Length = 502
Score = 85.5 bits (210), Expect = 1e-16
Identities = 74/235 (31%), Positives = 88/235 (37%), Gaps = 57/235 (24%)
Query: 302 AVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPP----PTPR 357
A + M P PPPPP PP S P+ P G+ P P
Sbjct: 291 ASARHMALNRPQQPPPPP---------PPQAPEGSQASAPMAPADYGMLPAQIIEYYNPS 341
Query: 358 GPPPPGRGGPPPP--PPPATGRSGPL------------------PPPPPGAG----GPPM 393
GPPPP PPPP P T PL PP PP G PP
Sbjct: 342 GPPPP----PPPPVIPSAQTAFVSPLQMPMQPPFPASASSTHAAPPHPPSTGLLVTAPPP 397
Query: 394 PPPPPPPPPPPSSGNGPAPPPL-PPALVPAGGLAP-----GGGRGALLDQIRQGIQLNKT 447
P PPPPPP PP G+ + P+ P + A P R LL IR GIQL K
Sbjct: 398 PGPPPPPPGPPGPGSSLSSSPMHGPPVAEAKRQEPAQPPISDARSDLLAAIRMGIQLKKV 457
Query: 448 PGAPESSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDEDDEWDD 502
E A + P VG + + R A+ SD +D DE ++W D
Sbjct: 458 QEQREQEAKREP-------VGNDVATILSRRIAVEYSDSDDDSEFDE---NDWSD 502
Score = 36.6 bits (83), Expect = 0.055
Identities = 35/145 (24%), Positives = 49/145 (33%), Gaps = 41/145 (28%)
Query: 351 PPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSG--- 407
P P TP G PP P + PP A + P PPPPPP
Sbjct: 260 PQPVTPSY----AAGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPPPQAPEG 315
Query: 408 -------------------------NGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGI 442
+GP PPP PP ++P+ + A + ++ +
Sbjct: 316 SQASAPMAPADYGMLPAQIIEYYNPSGPPPPP-PPPVIPS-------AQTAFVSPLQMPM 367
Query: 443 QLNKTPGAPESSALQPPPQSSEGLV 467
Q P + S+ PP S GL+
Sbjct: 368 Q-PPFPASASSTHAAPPHPPSTGLL 391
Score = 30.4 bits (67), Expect = 3.9
Identities = 36/131 (27%), Positives = 43/131 (32%), Gaps = 9/131 (6%)
Query: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA-PPPLPP 417
P P P P P+ +G +PP P + PP + N P PPP PP
Sbjct: 251 PATPNHSLHPQPVTPSYA-AGDVPPHGPASQAAEHEYRPPSASARHMALNRPQQPPPPPP 309
Query: 418 ALVPAGGLAPG----GGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHV 473
P G A G L QI I+ G P P + V L
Sbjct: 310 PQAPEGSQASAPMAPADYGMLPAQI---IEYYNPSGPPPPPPPPVIPSAQTAFVSPLQMP 366
Query: 474 MQKRSRAIHSS 484
MQ A SS
Sbjct: 367 MQPPFPASASS 377
Score = 30.0 bits (66), Expect = 5.1
Identities = 21/68 (30%), Positives = 24/68 (35%), Gaps = 16/68 (23%)
Query: 155 DRRQLPPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRG 214
+R Q PPPP P P P G Q P+ P G+ I I G
Sbjct: 299 NRPQQPPPPPP------------PQAPEGSQASAPMAPADYGMLPAQI----IEYYNPSG 342
Query: 215 LPAPGPSP 222
P P P P
Sbjct: 343 PPPPPPPP 350
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 83.6 bits (205), Expect = 4e-16
Identities = 57/124 (45%), Positives = 61/124 (49%), Gaps = 31/124 (25%)
Query: 313 LPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372
LPP PPP G RPP G G GPLP + PP P P PP GPPP PP
Sbjct: 430 LPPGPPP--GAPPFLRPP---GMPGLRGPLPR----LLPPGPPPGRPP-----GPPPGPP 475
Query: 373 PATGRSGPLPPPPPGAGGPP-MPPPPPPPPPPPSSGN---------GPAPPPL-PPALVP 421
P LPP PP G PP +PPP PP PPP G GPAPP L PPA +P
Sbjct: 476 PG------LPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLP 529
Query: 422 AGGL 425
G+
Sbjct: 530 NPGV 533
Score = 81.6 bits (200), Expect = 1e-15
Identities = 70/204 (34%), Positives = 89/204 (43%), Gaps = 33/204 (16%)
Query: 283 DAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPL 342
D+E K +++ + +Q+ P PPS Q+ PP+ G P
Sbjct: 363 DSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPS----QIQAPPMPGPPPLGPPPA 418
Query: 343 PPV-PLGIAPPPPTPRGPPPPGRGGPP-PPPPPATGRSGPLP---PPPPGAGGPPMPPPP 397
PP+ P G PP P GPPP G PP PP G GPLP PP P G PP PPP
Sbjct: 419 PPLRPPG--PPTGLPPGPPP---GAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPG 473
Query: 398 PP---PPPPPSSGNGP-APPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPES 453
PP PP PP G P PPP PP + P PG R L+ P P
Sbjct: 474 PPPGLPPGPPPRGPPPRLPPPAPPGIPPP---RPGMMRPPLV-----------PPLGPAP 519
Query: 454 SALQPP-PQSSEGLVGALMHVMQK 476
L PP P + G++ A +++Q+
Sbjct: 520 PGLFPPAPLPNPGVLSAPPNLIQR 543
Score = 33.1 bits (74), Expect = 0.60
Identities = 45/168 (26%), Positives = 58/168 (34%), Gaps = 40/168 (23%)
Query: 341 PLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPP-----PPPGAGGPPMPP 395
PLP +P AP + P PG PP T GP P G G P +PP
Sbjct: 140 PLPDMPH--APSNILIQDIPLPG--AQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPP 195
Query: 396 PPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSA 455
PP PPP P PP +V G + G L+ P +
Sbjct: 196 GRKPPGPPPG--------PPPPQVVQMYGR-------------KVGFALDLPPRRRDEDM 234
Query: 456 LQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGEDQAGDEDE-DDEWDD 502
L P + G + S D+G + D+D+ DD DD
Sbjct: 235 LYSPELAQRG---------HDDDVSSTSEDDGYPEDMDQDKHDDSTDD 273
Score = 30.8 bits (68), Expect = 3.0
Identities = 23/80 (28%), Positives = 36/80 (45%), Gaps = 17/80 (21%)
Query: 130 DEDEAQAFRALVQEKIQKRNQRQS--------GDRRQLPP---PPTPANEERRGGLPPL- 177
D+DE + + +++ QK+++ +S ++Q PP PP+ G PPL
Sbjct: 355 DDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414
Query: 178 -----PLHPGGDQGGPPVGP 192
PL P G G P GP
Sbjct: 415 PPPAPPLRPPGPPTGLPPGP 434
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 83.2 bits (204), Expect = 5e-16
Identities = 62/189 (32%), Positives = 80/189 (42%), Gaps = 19/189 (10%)
Query: 286 TSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPV 345
TS L+ + + +R Q+ L PPPPP P PP PLP
Sbjct: 111 TSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPA----PGPPQDISEPPGGSPLPSP 166
Query: 346 PLGIAPPPPTP-RGPPPPGRGGPPPP-----PPPATGRSGPLPPPPPGAGGPPMPP---- 395
P PPPP PPPP PPPP PP T S +P PP PP PP
Sbjct: 167 PSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFI--PPAPPLAFL 224
Query: 396 -PPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLN--KTPGAPE 452
PPPPP P P+ +P + L P GG+ AL + + + + ++P P+
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 453 SSALQPPPQ 461
SAL P P+
Sbjct: 285 GSALGPNPE 293
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/163 (30%), Positives = 58/163 (35%), Gaps = 16/163 (9%)
Query: 309 RQEPLPPPPP------PSRGGNQLPRPPIVGGNKGRSG-PLPPVPLGIAPPPPT-PRGPP 360
R +PPP P P + + PR K S PLPP I P P P
Sbjct: 300 RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-SFHIRPASQVYPDRAP 358
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
P G PA+ R G G P P PP PPP PP P PPLPPA
Sbjct: 359 EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP---PPAPPLPPAAP 415
Query: 421 P----AGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPP 459
P P G ++ P +PE++A P
Sbjct: 416 PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP 458
Score = 37.7 bits (86), Expect = 0.025
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
PPPP P PP PA G PP P P PP+ G P A
Sbjct: 987 PPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYA 1046
Query: 419 LVPAGGLA--PGGGRGALLDQIRQGIQLNKTPGAP 451
AGGL GGGR + ++ G + ++ PG P
Sbjct: 1047 --GAGGLERFSGGGRSLIKKRLYVG-EPHRGPGLP 1078
Score = 36.2 bits (82), Expect = 0.071
Identities = 92/394 (23%), Positives = 130/394 (32%), Gaps = 86/394 (21%)
Query: 148 RNQRQSGDRRQLPPP------PTPANEERRGGLPPL--PLHPGGDQGGPPVG----PLSL 195
++Q Q+ +R PPP P P LPP PL PP G P S
Sbjct: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
Query: 196 GLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSH-----V 250
A NP + P P+ ++ + +++ G+ + +SH V
Sbjct: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKL-RNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 251 GWDPQNGFDVNNLDPDLRSLFSRA------GISE-----AQLTDAETSKLI----YDFIE 295
+ G L P+ +L S G+ E + LT+ E + + D+I
Sbjct: 497 APQSKEGKKGPRL-PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIP 555
Query: 296 DQGGLEAVRQ-----EMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGP--------- 341
+VRQ E R PS G P+P + GG +G
Sbjct: 556 QDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPV 614
Query: 342 ---LPPVPLGIAPP----PPTPRGPPPPGRGGPPPPPP------PATGRSGPLPPPPP-- 386
LPP + P P GP P + P P P PAT L P P
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLK 674
Query: 387 GAGGPPMPPPPPPPPPPPSSG---------------NGPAPPPLPPALVPAGGLAPGGGR 431
GP P P S+ +GPA P PA + G
Sbjct: 675 ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE 734
Query: 432 GALLDQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
G+ + R T GA S+A PP++S G
Sbjct: 735 GSPSEATRL-----PTQGARSSAAF--PPKTSPG 761
Score = 34.3 bits (77), Expect = 0.27
Identities = 49/211 (23%), Positives = 64/211 (30%), Gaps = 68/211 (32%)
Query: 312 PLPPP------PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP---- 361
P PPP PP + +P PP P PP+ PPPP P PP
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDF------IPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 362 ----------PG-------------------RGGPPPPPPPATG--------------RS 378
PG R PP P G RS
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS 301
Query: 379 GPLPPPPP--GAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA--LVPAGGLAPGGG---- 430
+PPP P + P P ++ P+ PLPP+ + PA + P
Sbjct: 302 FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
Query: 431 -RGALLDQIRQGIQLNKTPGAPESSALQPPP 460
G L +L ++ + A PPP
Sbjct: 362 CPGELKATAPASPRLGQSQSQADERAGTPPP 392
Score = 32.7 bits (73), Expect = 0.79
Identities = 42/192 (21%), Positives = 56/192 (29%), Gaps = 36/192 (18%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSG-------PLPPVPLGIAPPPPTPRGPPPP-- 362
PLPP PP + PP +S P PP P A P P
Sbjct: 409 PLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
Query: 363 ---------------------GRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401
R GP P G+ GP P P PP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 402 PPPSSGNGPAPPPLPPAL-VPAGGLAPGGGRGALLDQIRQGIQLNKTPGA-----PESSA 455
G+ P+L +P+ P + QIR ++ + A P +
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 456 LQPPPQSSEGLV 467
L P P+ G +
Sbjct: 589 LPPKPRLEGGRI 600
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 83.2 bits (204), Expect = 5e-16
Identities = 62/189 (32%), Positives = 80/189 (42%), Gaps = 19/189 (10%)
Query: 286 TSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPV 345
TS L+ + + +R Q+ L PPPPP P PP PLP
Sbjct: 111 TSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPA----PGPPQDISEPPGGSPLPSP 166
Query: 346 PLGIAPPPPTP-RGPPPPGRGGPPPP-----PPPATGRSGPLPPPPPGAGGPPMPP---- 395
P PPPP PPPP PPPP PP T S +P PP PP PP
Sbjct: 167 PSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFI--PPAPPLAFL 224
Query: 396 -PPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLN--KTPGAPE 452
PPPPP P P+ +P + L P GG+ AL + + + + ++P P+
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 453 SSALQPPPQ 461
SAL P P+
Sbjct: 285 GSALGPNPE 293
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/163 (30%), Positives = 58/163 (35%), Gaps = 16/163 (9%)
Query: 309 RQEPLPPPPP------PSRGGNQLPRPPIVGGNKGRSG-PLPPVPLGIAPPPPT-PRGPP 360
R +PPP P P + + PR K S PLPP I P P P
Sbjct: 300 RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-SFHIRPASQVYPDRAP 358
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
P G PA+ R G G P P PP PPP PP P PPLPPA
Sbjct: 359 EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP---PPAPPLPPAAP 415
Query: 421 P----AGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPP 459
P P G ++ P +PE++A P
Sbjct: 416 PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP 458
Score = 37.7 bits (86), Expect = 0.025
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
PPPP P PP PA G PP P P PP+ G P A
Sbjct: 987 PPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYA 1046
Query: 419 LVPAGGLA--PGGGRGALLDQIRQGIQLNKTPGAP 451
AGGL GGGR + ++ G + ++ PG P
Sbjct: 1047 --GAGGLERFSGGGRSLIKKRLYVG-EPHRGPGLP 1078
Score = 36.2 bits (82), Expect = 0.071
Identities = 92/394 (23%), Positives = 130/394 (32%), Gaps = 86/394 (21%)
Query: 148 RNQRQSGDRRQLPPP------PTPANEERRGGLPPL--PLHPGGDQGGPPVG----PLSL 195
++Q Q+ +R PPP P P LPP PL PP G P S
Sbjct: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
Query: 196 GLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSH-----V 250
A NP + P P+ ++ + +++ G+ + +SH V
Sbjct: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKL-RNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 251 GWDPQNGFDVNNLDPDLRSLFSRA------GISE-----AQLTDAETSKLI----YDFIE 295
+ G L P+ +L S G+ E + LT+ E + + D+I
Sbjct: 497 APQSKEGKKGPRL-PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIP 555
Query: 296 DQGGLEAVRQ-----EMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGP--------- 341
+VRQ E R PS G P+P + GG +G
Sbjct: 556 QDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPV 614
Query: 342 ---LPPVPLGIAPP----PPTPRGPPPPGRGGPPPPPP------PATGRSGPLPPPPP-- 386
LPP + P P GP P + P P P PAT L P P
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLK 674
Query: 387 GAGGPPMPPPPPPPPPPPSSG---------------NGPAPPPLPPALVPAGGLAPGGGR 431
GP P P S+ +GPA P PA + G
Sbjct: 675 ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE 734
Query: 432 GALLDQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
G+ + R T GA S+A PP++S G
Sbjct: 735 GSPSEATRL-----PTQGARSSAAF--PPKTSPG 761
Score = 34.3 bits (77), Expect = 0.27
Identities = 49/211 (23%), Positives = 64/211 (30%), Gaps = 68/211 (32%)
Query: 312 PLPPP------PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP---- 361
P PPP PP + +P PP P PP+ PPPP P PP
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDF------IPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 362 ----------PG-------------------RGGPPPPPPPATG--------------RS 378
PG R PP P G RS
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS 301
Query: 379 GPLPPPPP--GAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA--LVPAGGLAPGGG---- 430
+PPP P + P P ++ P+ PLPP+ + PA + P
Sbjct: 302 FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
Query: 431 -RGALLDQIRQGIQLNKTPGAPESSALQPPP 460
G L +L ++ + A PPP
Sbjct: 362 CPGELKATAPASPRLGQSQSQADERAGTPPP 392
Score = 32.7 bits (73), Expect = 0.79
Identities = 42/192 (21%), Positives = 56/192 (29%), Gaps = 36/192 (18%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSG-------PLPPVPLGIAPPPPTPRGPPPP-- 362
PLPP PP + PP +S P PP P A P P
Sbjct: 409 PLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
Query: 363 ---------------------GRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401
R GP P G+ GP P P PP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 402 PPPSSGNGPAPPPLPPAL-VPAGGLAPGGGRGALLDQIRQGIQLNKTPGA-----PESSA 455
G+ P+L +P+ P + QIR ++ + A P +
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 456 LQPPPQSSEGLV 467
L P P+ G +
Sbjct: 589 LPPKPRLEGGRI 600
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 83.2 bits (204), Expect = 5e-16
Identities = 62/189 (32%), Positives = 80/189 (42%), Gaps = 19/189 (10%)
Query: 286 TSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPV 345
TS L+ + + +R Q+ L PPPPP P PP PLP
Sbjct: 111 TSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPA----PGPPQDISEPPGGSPLPSP 166
Query: 346 PLGIAPPPPTP-RGPPPPGRGGPPPP-----PPPATGRSGPLPPPPPGAGGPPMPP---- 395
P PPPP PPPP PPPP PP T S +P PP PP PP
Sbjct: 167 PSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFI--PPAPPLAFL 224
Query: 396 -PPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLN--KTPGAPE 452
PPPPP P P+ +P + L P GG+ AL + + + + ++P P+
Sbjct: 225 APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK 284
Query: 453 SSALQPPPQ 461
SAL P P+
Sbjct: 285 GSALGPNPE 293
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/163 (30%), Positives = 58/163 (35%), Gaps = 16/163 (9%)
Query: 309 RQEPLPPPPP------PSRGGNQLPRPPIVGGNKGRSG-PLPPVPLGIAPPPPT-PRGPP 360
R +PPP P P + + PR K S PLPP I P P P
Sbjct: 300 RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP-SFHIRPASQVYPDRAP 358
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
P G PA+ R G G P P PP PPP PP P PPLPPA
Sbjct: 359 EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP---PPAPPLPPAAP 415
Query: 421 P----AGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPP 459
P P G ++ P +PE++A P
Sbjct: 416 PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP 458
Score = 37.7 bits (86), Expect = 0.025
Identities = 31/95 (32%), Positives = 38/95 (40%), Gaps = 5/95 (5%)
Query: 359 PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA 418
PPPP P PP PA G PP P P PP+ G P A
Sbjct: 987 PPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYA 1046
Query: 419 LVPAGGLA--PGGGRGALLDQIRQGIQLNKTPGAP 451
AGGL GGGR + ++ G + ++ PG P
Sbjct: 1047 --GAGGLERFSGGGRSLIKKRLYVG-EPHRGPGLP 1078
Score = 36.2 bits (82), Expect = 0.071
Identities = 92/394 (23%), Positives = 130/394 (32%), Gaps = 86/394 (21%)
Query: 148 RNQRQSGDRRQLPPP------PTPANEERRGGLPPL--PLHPGGDQGGPPVG----PLSL 195
++Q Q+ +R PPP P P LPP PL PP G P S
Sbjct: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
Query: 196 GLATVDIQNPDITSSRYRGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSH-----V 250
A NP + P P+ ++ + +++ G+ + +SH V
Sbjct: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKL-RNELAAYLCGSRREDRFLSHRPGPTV 496
Query: 251 GWDPQNGFDVNNLDPDLRSLFSRA------GISE-----AQLTDAETSKLI----YDFIE 295
+ G L P+ +L S G+ E + LT+ E + + D+I
Sbjct: 497 APQSKEGKKGPRL-PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIP 555
Query: 296 DQGGLEAVRQ-----EMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGP--------- 341
+VRQ E R PS G P+P + GG +G
Sbjct: 556 QDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPV 614
Query: 342 ---LPPVPLGIAPP----PPTPRGPPPPGRGGPPPPPP------PATGRSGPLPPPPP-- 386
LPP + P P GP P + P P P PAT L P P
Sbjct: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLK 674
Query: 387 GAGGPPMPPPPPPPPPPPSSG---------------NGPAPPPLPPALVPAGGLAPGGGR 431
GP P P S+ +GPA P PA + G
Sbjct: 675 ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE 734
Query: 432 GALLDQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
G+ + R T GA S+A PP++S G
Sbjct: 735 GSPSEATRL-----PTQGARSSAAF--PPKTSPG 761
Score = 34.3 bits (77), Expect = 0.27
Identities = 49/211 (23%), Positives = 64/211 (30%), Gaps = 68/211 (32%)
Query: 312 PLPPP------PPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP---- 361
P PPP PP + +P PP P PP+ PPPP P PP
Sbjct: 188 PPPPPVLEALSPPHTLSSPSIPTPPDF------IPPAPPLAFLAPPPPPVPAPAPPAPAS 241
Query: 362 ----------PG-------------------RGGPPPPPPPATG--------------RS 378
PG R PP P G RS
Sbjct: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS 301
Query: 379 GPLPPPPP--GAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPA--LVPAGGLAPGGG---- 430
+PPP P + P P ++ P+ PLPP+ + PA + P
Sbjct: 302 FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
Query: 431 -RGALLDQIRQGIQLNKTPGAPESSALQPPP 460
G L +L ++ + A PPP
Sbjct: 362 CPGELKATAPASPRLGQSQSQADERAGTPPP 392
Score = 32.7 bits (73), Expect = 0.79
Identities = 42/192 (21%), Positives = 56/192 (29%), Gaps = 36/192 (18%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSG-------PLPPVPLGIAPPPPTPRGPPPP-- 362
PLPP PP + PP +S P PP P A P P
Sbjct: 409 PLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
Query: 363 ---------------------GRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPP 401
R GP P G+ GP P P PP P
Sbjct: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
Query: 402 PPPSSGNGPAPPPLPPAL-VPAGGLAPGGGRGALLDQIRQGIQLNKTPGA-----PESSA 455
G+ P+L +P+ P + QIR ++ + A P +
Sbjct: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
Query: 456 LQPPPQSSEGLV 467
L P P+ G +
Sbjct: 589 LPPKPRLEGGRI 600
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 83.2 bits (204), Expect = 5e-16
Identities = 66/211 (31%), Positives = 85/211 (40%), Gaps = 74/211 (35%)
Query: 314 PPP--PPPSRGGNQLPRPPIVGGNKGRSGP-------------------LPPVPLGIAPP 352
PPP PP G ++PRP V +K + LPP+P PP
Sbjct: 746 PPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLP----PP 801
Query: 353 PPTPRGPPPPGRGGPPPPPPPATGRSGPLP-PPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411
PP+ PPP GPP PP + P P PG P+PPPPPPPPP P GP
Sbjct: 802 PPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPG----PLPPPPPPPPPVP----GPV 853
Query: 412 PPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALM 471
P PP LVP G PGGG L++ I +N
Sbjct: 854 TLP-PPQLVPEG--TPGGGGPPALEEDLTVININ-------------------------- 884
Query: 472 HVMQKRSRAIHSSDEGEDQAGDEDEDDEWDD 502
SSDE E++ +E+E++E ++
Sbjct: 885 -----------SSDEEEEEEEEEEEEEEEEE 904
Score = 51.2 bits (121), Expect = 2e-06
Identities = 30/80 (37%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPP--GAGGPPMPPPPPPPPPPPSSGNG 409
PP P GP P PPP P+ R+ P PP P G P P P P PS+G
Sbjct: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPV 695
Query: 410 PAPPPLPPALVPAGGLAPGG 429
P+ P PP GL+ G
Sbjct: 696 PSARPGPPTTANHLGLSVPG 715
Score = 46.2 bits (108), Expect = 7e-05
Identities = 37/94 (39%), Positives = 45/94 (47%), Gaps = 17/94 (18%)
Query: 342 LPPV-PLGIAPPPPTPRGPPP---PGRGGP--PPPPPPATGRSGPLPPPPPGAGGPPMP- 394
+PP+ P+G P P P PP P R P PP P P+ G S P P P AG PMP
Sbjct: 635 VPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVG-SMPSAGPMPSAG--PMPS 691
Query: 395 --PPPPPPPPPPSSGNG-----PAPPPLPPALVP 421
P P P PP++ N P +PP L+P
Sbjct: 692 AGPVPSARPGPPTTANHLGLSVPGLVSVPPRLLP 725
Score = 38.1 bits (87), Expect = 0.019
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 3/67 (4%)
Query: 368 PPPPPPATGRSGPLPPPPPGAGGPPMPPP-PPPPPPPPSSGNGPAPPPLPPA-LVPAGGL 425
PP P P P PPP A P PP P P P PS G+ P+ P+P A +P+ G
Sbjct: 636 PPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHP-PGPMPSVGSMPSAGPMPSAGPMPSAGP 694
Query: 426 APGGGRG 432
P G
Sbjct: 695 VPSARPG 701
Score = 37.0 bits (84), Expect = 0.042
Identities = 22/57 (38%), Positives = 25/57 (43%), Gaps = 22/57 (38%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPP 368
PLPPPPPP PP+ P P+ + PP P G PG GGPP
Sbjct: 838 PLPPPPPPP--------PPV------------PGPVTLPPPQLVPEG--TPGGGGPP 872
Score = 36.2 bits (82), Expect = 0.071
Identities = 19/49 (38%), Positives = 22/49 (44%)
Query: 382 PPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGG 430
P PP P P P P PPP + APP PP +P+ G P G
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAG 681
Score = 36.2 bits (82), Expect = 0.071
Identities = 74/313 (23%), Positives = 101/313 (32%), Gaps = 63/313 (20%)
Query: 162 PPTPANEERR------GGLPPLPLHPGGDQGGPPV-GPLSLGLATVDIQNPDITSSRYRG 214
PP PA EE G LPP P P PPV GP++L P + G
Sbjct: 821 PPVPAKEEPEELPAAPGPLPPPPPPP------PPVPGPVTL-------PPPQLVPE---G 864
Query: 215 LPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRA 274
P G PA ++ I+ +D + + + D + D F
Sbjct: 865 TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEE 924
Query: 275 GISEAQLTDAETSKLIYDFIEDQGGLEAVRQEM--RRQEPLPPPPPPSRGGNQLPRPPIV 332
E + + +F E++G LE +E +E L G
Sbjct: 925 EEEEEEFEE--------EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG--------TA 968
Query: 333 GGNKGRSGPLPP-VPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGP 391
GG P PP +P + PP P+ P P P P P GA
Sbjct: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPE-----PEPEPGLLLEVEEPGTEEERGADTA 1023
Query: 392 P--MPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPG 449
P P P G PA P P LV AP LL++ +
Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQELVEEEPSAP----PTLLEEETE--------- 1070
Query: 450 APESSALQPPPQS 462
S +QPPP++
Sbjct: 1071 -DGSDKVQPPPET 1082
Score = 31.6 bits (70), Expect = 1.8
Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 10/80 (12%)
Query: 388 AGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKT 447
AGG PPPP PP+ +PP + P P GL LL+ G + +
Sbjct: 968 AGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGL--------LLEVEEPGTEEER- 1018
Query: 448 PGAPESSALQPPPQSSEGLV 467
GA + L P S+G V
Sbjct: 1019 -GADTAPTLAPEALPSQGEV 1037
>gi|41349484 proline-rich protein BstNI subfamily 1 isoform 2
preproprotein [Homo sapiens]
Length = 198
Score = 82.8 bits (203), Expect = 7e-16
Identities = 60/154 (38%), Positives = 66/154 (42%), Gaps = 40/154 (25%)
Query: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAP----------PPPTPRGPP 360
+P PPPPP + PP GGNK + P P P G P PP P+GPP
Sbjct: 46 KPQGPPPPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 101
Query: 361 PPGRGGPPPPPPPATGRSGPLPPPP------PGAGG--------PPMPPPPPPP------ 400
P +GG P PPP G PPPP P GG PP P PP
Sbjct: 102 P--QGGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNP 159
Query: 401 --PPPPSSGNGPAPPPLPPALVPAG-GLAPGGGR 431
PPPP+ GN P P PPA P G P GGR
Sbjct: 160 QGPPPPAGGN-PQQPQAPPAGQPQGPPRPPQGGR 192
Score = 74.7 bits (182), Expect = 2e-13
Identities = 59/176 (33%), Positives = 68/176 (38%), Gaps = 51/176 (28%)
Query: 322 GGNQLPRPPIVGGNKGRSGPLPP-VPLGIAPPPP---TPRGPPPPGRGGPPPP------- 370
G Q P P GGNK + P PP P G PPP P+GPPPPG+ PPP
Sbjct: 34 GNPQGPSPQ--GGNKPQGPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 89
Query: 371 ----------PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNG----------- 409
PPP G+ P PPP G P PPPP P PP+ G
Sbjct: 90 PRSPPGKPQGPPPQGGK--PQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK 147
Query: 410 PAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
P PP P G P GG + P AP + Q PP+ +G
Sbjct: 148 PQGPPQQEGNNPQGPPPPAGGN-------------PQQPQAPPAGQPQGPPRPPQG 190
Score = 73.9 bits (180), Expect = 3e-13
Identities = 55/154 (35%), Positives = 61/154 (39%), Gaps = 30/154 (19%)
Query: 324 NQLPRPPIVGGNKGRSGPLPP---VPLGIAPPPPTPRGPPPPGRGGP--PPPP-----PP 373
+Q P ++ GN GP P P G PPP P+GPPP G P PPPP PP
Sbjct: 24 SQEESPSLIAGNP--QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 81
Query: 374 ATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGA 433
G P PPG P P P PPP GN P PP PP P G A GG +
Sbjct: 82 PQGDKSRSPRSPPGKPQGPPPQGGKPQGPPPQGGNKPQGPP-PPG-KPQGPPAQGGSKSQ 139
Query: 434 LLDQIRQGIQLNKTPGAPESSALQ-------PPP 460
PG P+ Q PPP
Sbjct: 140 ---------SARSPPGKPQGPPQQEGNNPQGPPP 164
Score = 73.9 bits (180), Expect = 3e-13
Identities = 57/147 (38%), Positives = 61/147 (41%), Gaps = 47/147 (31%)
Query: 314 PPPP-----PPSRGGNQLPRPPIVG--------GNKGRSGPLPP-VPLGIAPPPPTPRGP 359
PPPP PP +GGN+ PP G G+K RS PP P G P P+GP
Sbjct: 51 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGP 110
Query: 360 PPPGRGGP--PPPP-----PPATG-------RSGPLPP-------------PPPGAGGPP 392
PP G P PPPP PPA G RS P P PPP AGG P
Sbjct: 111 PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 170
Query: 393 MPPPPPP------PPPPPSSGNGPAPP 413
P PP PP PP G PP
Sbjct: 171 QQPQAPPAGQPQGPPRPPQGGRPSRPP 197
Score = 65.9 bits (159), Expect = 8e-11
Identities = 44/117 (37%), Positives = 48/117 (41%), Gaps = 21/117 (17%)
Query: 309 RQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG-----------IAPPPPTPR 357
R P P PP +GG PP GGNK + P P P G PP P+
Sbjct: 91 RSPPGKPQGPPPQGGKPQGPPP-QGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQ 149
Query: 358 GPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP 414
GPP P PPPPA G P P P AG P PP PP G P+ PP
Sbjct: 150 GPPQQEGNNPQGPPPPAGG--NPQQPQAPPAGQPQGPPRPP-------QGGRPSRPP 197
Score = 52.4 bits (124), Expect = 1e-06
Identities = 64/220 (29%), Positives = 77/220 (35%), Gaps = 65/220 (29%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
P P+P + G PP PG QG PP G ++ +G P PG
Sbjct: 36 PQGPSPQGGNKPQGPPP---PPGKPQGPPPQG-----------------GNKPQGPPPPG 75
Query: 220 -----PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRA 274
P DK RS + K P G K G PQ G P + A
Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQ---GPPPQGGNKPQGPPPPGKPQGPPA 132
Query: 275 GISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGN--QLPRPPIV 332
QGG ++ + R P P PP + GN Q P PP
Sbjct: 133 ----------------------QGGSKS---QSARSPPGKPQGPPQQEGNNPQGPPPP-A 166
Query: 333 GGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPP 372
GGN P P APP P+GPP P +GG P PP
Sbjct: 167 GGN-----PQQPQ----APPAGQPQGPPRPPQGGRPSRPP 197
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 82.4 bits (202), Expect = 9e-16
Identities = 89/278 (32%), Positives = 105/278 (37%), Gaps = 59/278 (21%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
PPPP P PP PL G PP P S + D TSS R P
Sbjct: 7 PPPPLPP--------PPPPL------GAPPPPPPSAPPVSTD------TSSLRRADPKGR 46
Query: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVN----NLDPDLRSLFSRAG 275
+ + G + I S + S G + + G N + P L LF+
Sbjct: 47 SALLADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGF 106
Query: 276 --ISEAQLTDAETSKLIYDFIEDQG-GLEAVRQEMRRQE---PLPPPPPPSRGGNQLPRP 329
+ A D K QG G A + + PL PP P G
Sbjct: 107 PVLRPAGQRDVAGGKT------GQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAH- 159
Query: 330 PIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPL--PPPPPG 387
G + PP P APPPPTP PPPP PPP P ++ PL PP P
Sbjct: 160 -------GAARTAPPRPNVPAPPPPTPPPPPPP----LPPPLPSSSPIKTPLVSPPGPLT 208
Query: 388 AGG-----PPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
G PP+P PPPPPPPP P PPPLPPA V
Sbjct: 209 KGNLPVVAPPVPCAPPPPPPPPP----PTPPPLPPASV 242
Score = 68.6 bits (166), Expect = 1e-11
Identities = 60/169 (35%), Positives = 63/169 (37%), Gaps = 67/169 (39%)
Query: 308 RRQEPLPPPPPPSRGGNQLPRP-----PIVGGNKGRSGPL---------PPVPLGIAPPP 353
R P PPPP P LP P PI GPL PPVP APPP
Sbjct: 168 RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVP--CAPPP 225
Query: 354 PTPRGPPPPGRGGPPPPPPPATGRSG-------------PLPPPPP-------------- 386
P P PPPP PPP PPA+ S P+PPP P
Sbjct: 226 PPP--PPPP----TPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP 279
Query: 387 -----GAGGPPMPPPPPPP----------PPPPSSG---NGPAPPPLPP 417
A PP PPPP PP P PP G + PPPLPP
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPP 328
Score = 62.8 bits (151), Expect = 7e-10
Identities = 40/90 (44%), Positives = 47/90 (52%), Gaps = 17/90 (18%)
Query: 380 PLPPPPPGAGGPPMPPPPPP--PPPPPSSGNGPAPPPLPPALVPAGGL--APGGGRGALL 435
P+PPPPP PP+PPPPPP PPPP PP PP L A GR ALL
Sbjct: 2 PVPPPPP----PPLPPPPPPLGAPPPP-------PPSAPPVSTDTSSLRRADPKGRSALL 50
Query: 436 DQIRQGIQLNKTPGAPESSALQPPPQSSEG 465
I+QG +L K + SA P +SS+G
Sbjct: 51 ADIQQGTRLRKVTQINDRSA--PQIESSKG 78
Score = 62.0 bits (149), Expect = 1e-09
Identities = 63/193 (32%), Positives = 71/193 (36%), Gaps = 53/193 (27%)
Query: 297 QGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPP------------ 344
+G L V + P PPPPPP P PP PLPP
Sbjct: 209 KGNLPVVAPPVPCAPPPPPPPPP-------PTPP----------PLPPASVLSDKAVKPQ 251
Query: 345 -VPLGIAP-PPPTPRGPP---PPGRGGPPPPPPPATGRSGPLPPPPPGAGGPP---MPPP 396
PL + P PPP P PP P + P P A P PP PP A P +P P
Sbjct: 252 LAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP 311
Query: 397 P---------PPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKT 447
P PPP PP S + APP A AP G + L + R G
Sbjct: 312 PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQ-PFLQKKRHG-----R 365
Query: 448 PGAPESSALQPPP 460
PGA L PPP
Sbjct: 366 PGA-GGGKLNPPP 377
Score = 61.6 bits (148), Expect = 2e-09
Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 16/131 (12%)
Query: 312 PLPPPPP--PSRGGNQLPRPPIVGGNKGRSGPLPPVPL---GIAPPPPTPRGPPPPGRGG 366
P+PPP P P G L P + P PP PL P + PP PG
Sbjct: 259 PIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNS 318
Query: 367 PPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPP-----------SSGNGPAPPPL 415
PPP +S PP AG +P PP PP P + G PPP
Sbjct: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA 378
Query: 416 PPALVPAGGLA 426
PPA P L+
Sbjct: 379 PPARSPTTELS 389
Score = 60.8 bits (146), Expect = 3e-09
Identities = 64/206 (31%), Positives = 78/206 (37%), Gaps = 33/206 (16%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGN--KGRSGPL--PPVP--LGIAPP---PPTPRGPPPP 362
P PPPPPP LP ++ K + PL PP+P L + PP P P P
Sbjct: 223 PPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP 282
Query: 363 GRGG-----PPPPPPPATGRS--GPLPPPP-PGAGGPPMPPPPPPP------PPPPSSGN 408
+ PPPP PP S LP PP PG PPP PP PP +G
Sbjct: 283 AQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGA 342
Query: 409 GPAP-PPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESS---ALQPPPQSSE 464
P PP PP P G GA G +LN P P S L Q +
Sbjct: 343 QALPAPPAPPGSQPFLQKKRHGRPGA------GGGKLNPPPAPPARSPTTELSSKSQQAT 396
Query: 465 GLVGALMHVMQKRSRAIHSSDEGEDQ 490
Q R+ ++H D+ E +
Sbjct: 397 AWTPTQQPGGQLRNGSLHIIDDFESK 422
Score = 46.6 bits (109), Expect = 5e-05
Identities = 36/88 (40%), Positives = 37/88 (42%), Gaps = 24/88 (27%)
Query: 362 PGRGGPPPPPPPATGRSGPL-PPPPPGAGG-----------PPMP--PPPPPPPPPPSSG 407
PG P P P T SGPL PP P G PP P P PPPP PPP
Sbjct: 126 PGSRAPSPRLPNKT-ISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPP- 183
Query: 408 NGPAPPPLP-------PALVPAGGLAPG 428
P PPPLP P + P G L G
Sbjct: 184 -PPLPPPLPSSSPIKTPLVSPPGPLTKG 210
Score = 41.6 bits (96), Expect = 0.002
Identities = 23/49 (46%), Positives = 24/49 (48%), Gaps = 20/49 (40%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPP 360
P+PPPPPP P PP PP PLG APPPP P PP
Sbjct: 2 PVPPPPPP-------PLPP------------PPPPLG-APPPPPPSAPP 30
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 82.0 bits (201), Expect = 1e-15
Identities = 54/139 (38%), Positives = 61/139 (43%), Gaps = 27/139 (19%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPP--------TPRGPPPPG 363
P PP P G + P PP++ G P PP+P + PPPP P GP P G
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLP----PRPPLPESLPPPPPGGLPLPPMPPTGPAPSG 273
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGG--PPMPPPPPPPP----------PPPSSGNGPA 411
GPP PPPA G P P P A G PP P PP P PP S + PA
Sbjct: 274 PPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPA 333
Query: 412 P---PPLPPALVPAGGLAP 427
P PP P PA G+ P
Sbjct: 334 PGVHPPAPGVHPPAPGVHP 352
Score = 79.7 bits (195), Expect = 6e-15
Identities = 53/123 (43%), Positives = 60/123 (48%), Gaps = 25/123 (20%)
Query: 315 PPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPA 374
PP PPS + G G P PP+ G+ P PP P PPP GG P PP P
Sbjct: 217 PPAPPS----------LPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPP 266
Query: 375 TGRSGPLPPPPPGAGGPPMPPPPP---PPPP---PPSSG-NGPAP---PPLPPALVPAGG 424
T GP P PPG P +PPP P PP P PP+SG + PAP PP P PA G
Sbjct: 267 T---GPAPSGPPGP--PQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPG 321
Query: 425 LAP 427
+ P
Sbjct: 322 VHP 324
Score = 68.9 bits (167), Expect = 1e-11
Identities = 58/151 (38%), Positives = 62/151 (41%), Gaps = 40/151 (26%)
Query: 311 EPLPPPPPPSRGGNQLP-RPPIVGGNKGRSGPL----------PPVPL------GIAPPP 353
E LPPPPP GG LP PP G GP PP P+ G+ PP
Sbjct: 249 ESLPPPPP---GGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPA 305
Query: 354 PTPRGPPPPGRGGPPPPP----------PPATGRSGPLP---PPPPGAGGPPMP---PPP 397
P G PP G PP P PPA G P P PP PG PP P PP
Sbjct: 306 P---GVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGV-HPPAPGVHPPA 361
Query: 398 PPPPPPPSSGNGPAPPPLPPALVPAGGLAPG 428
P PPPS+G P P + PA APG
Sbjct: 362 PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPG 392
Score = 58.5 bits (140), Expect = 1e-08
Identities = 49/150 (32%), Positives = 55/150 (36%), Gaps = 36/150 (24%)
Query: 313 LPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPP------------PPTPRGPP 360
LPPP P + PP G + G PP P G+ PP PP P G
Sbjct: 280 LPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP-GVHPPAPGVHPPTSGVHPPAP-GVH 337
Query: 361 PPGRGGPPPPP---PPATGRSGPLPP--PPPGAGGPPMPP-----------------PPP 398
PP G PP P PPA G P P PPP AG P P PP
Sbjct: 338 PPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPA 397
Query: 399 PPPPPPSSGNGPAPPPLPPALVPAGGLAPG 428
P P + G P PP + P+ PG
Sbjct: 398 PGMHPQAPGVHPQPPGVHPSAPGVHPQPPG 427
Score = 55.5 bits (132), Expect = 1e-07
Identities = 46/136 (33%), Positives = 51/136 (37%), Gaps = 36/136 (26%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPG-------- 363
P P PP+ G + PP G + G PP P G+ PPP P PG
Sbjct: 332 PAPGVHPPAPGVH----PPAPGVHPPAPGVHPPAP-GVHPPPSAGVHPQAPGVHPAAPAV 386
Query: 364 ----RGGPPP------------PPPPATGRSGP-LPPPPPGAG------GPPMPPPPPPP 400
G PP P PP S P + P PPG PP P PP
Sbjct: 387 HPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLR 446
Query: 401 PPPPSSGNGPAPPPLP 416
PP PS G G PPP P
Sbjct: 447 PPLPSEGPGNIPPPPP 462
Score = 55.1 bits (131), Expect = 1e-07
Identities = 43/125 (34%), Positives = 50/125 (40%), Gaps = 16/125 (12%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPP-----PPTPRGPPPPGRGG 366
P P PP+ G + PP G + SG PP P G+ PP PP P PP
Sbjct: 304 PAPGVHPPAPGVH----PPAPGVHPPTSGVHPPAP-GVHPPAPGVHPPAPGVHPPAPGVH 358
Query: 367 PPPP---PPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAG 423
PP P PPP+ G P P A P PP P P P PP + P+
Sbjct: 359 PPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPS- 417
Query: 424 GLAPG 428
APG
Sbjct: 418 --APG 420
Score = 55.1 bits (131), Expect = 1e-07
Identities = 47/136 (34%), Positives = 52/136 (38%), Gaps = 32/136 (23%)
Query: 312 PLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPP-----PPTPRGPPPPGRGG 366
P P PP+ G + PP G + G PP P G+ PP PP P PPP G
Sbjct: 318 PAPGVHPPTSGVH----PPAPGVHPPAPGVHPPAP-GVHPPAPGVHPPAPGVHPPPSAGV 372
Query: 367 PPPPP-----------------PPATGRSGPLP---PPPPGAGGPPMPPPPPPPPPPPSS 406
P P PPA G P P PPG P P P PP S
Sbjct: 373 HPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVH-PSAPGVHPQPPGVHPS 431
Query: 407 GNGPAPP-PLPPALVP 421
G PP P+PP L P
Sbjct: 432 NPGVHPPTPMPPMLRP 447
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/97 (36%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
Query: 369 PPPPPATGRSGPLPPPPPGAGGPPMPPPP-----PPPPPPPSSGNGPAPPPLPPALVPAG 423
PP PP+ LP PPG PPPP PP PP P S P P LP +P
Sbjct: 217 PPAPPS------LPAGPPGV---KRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPT 267
Query: 424 GLAPGGGRG-ALLDQIRQGIQLNKTPGAPESSALQPP 459
G AP G G L G+ P +S + PP
Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPP 304
Score = 43.1 bits (100), Expect = 6e-04
Identities = 36/100 (36%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 317 PPPSRGGN-QLP--RPPIVGGNKGRSGPLPPVPLGIAPPPP----TPRGPPPPGRGGPPP 369
PPPS G + Q P P + G PP P G+ P P P G P G P
Sbjct: 366 PPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAP-GMHPQAPGVHPQPPGVHPSAPGVHPQ 424
Query: 370 PPPPATGRSGPLPPPP-PGAGGPPMPPPPPP--PPPPPSS 406
PP G PP P P PP+P P PPPPP++
Sbjct: 425 PPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN 464
Score = 31.6 bits (70), Expect = 1.8
Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 14/48 (29%)
Query: 393 MPPPPPPP-----------PPPPSSGNGPAPPPLPPALVPAGGLAPGG 429
M PP PP PPPP P PPLP +L P PGG
Sbjct: 214 MEKPPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP---PPGG 258
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 81.6 bits (200), Expect = 1e-15
Identities = 84/311 (27%), Positives = 111/311 (35%), Gaps = 67/311 (21%)
Query: 160 PPPPTPANEERRGGLPPLPLHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
PPPP P + PP P ++ PPV P T SR RG P
Sbjct: 430 PPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPA--------------TCSRKRGRPPLT 475
Query: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEA 279
PS ++ + + P+ + G P+ D + P +
Sbjct: 476 PSQRAEREAARAGPEGTSPPTPTPS---TATGGPPE---DSPTVAPKSTTFLKNIRQFIM 529
Query: 280 QLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRS 339
+ A +S++I + RR PP PP + + RPPI
Sbjct: 530 PVVSARSSRVI--------------KTPRRFMDEDPPKPPKVEVSPVLRPPITTS----- 570
Query: 340 GPLPPVPLGIAPPPPTPRGPPPPGRGGPPP---------PPPPATGRSGPLPPPPPGAGG 390
PPVP AP P PR P PP P P P T + LPPPPP
Sbjct: 571 ---PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPA--- 624
Query: 391 PPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTP-G 449
PPPPP P PPP+ PA P L+ A P + + + L P G
Sbjct: 625 ---PPPPPAPSPPPA----PATSSRRPLLLRAPQFTPSEAHLKIYESV-----LTPPPLG 672
Query: 450 APESSALQPPP 460
APE+ +PPP
Sbjct: 673 APEAPEPEPPP 683
Score = 69.7 bits (169), Expect = 6e-12
Identities = 43/116 (37%), Positives = 51/116 (43%), Gaps = 7/116 (6%)
Query: 349 IAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGN 408
+ PPP TP P PP PP PPP+T PL PPPP PP P PPPPP
Sbjct: 401 LPPPPLTPPAPSPP-----PPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEE 455
Query: 409 GPAPPPLPPALVPAGGLAP-GGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQSS 463
P PP +P G P + A + R G + P S+A PP+ S
Sbjct: 456 SP-PPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDS 510
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/163 (31%), Positives = 65/163 (39%), Gaps = 24/163 (14%)
Query: 278 EAQLTDAETSKLIYDFIEDQGGLE---AVRQEM-----RRQEPLPPPP--PPSRGGNQLP 327
E +L D E K + + +G + AV +EM + + LPPPP PP+ P
Sbjct: 358 EQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPS----P 413
Query: 328 RPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGR----GGPPPPPPPATGRSGPLPP 383
PP+ + PL P P PPP P PPPP + PPP P R PP
Sbjct: 414 PPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPP 473
Query: 384 PPPG-----AGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVP 421
P P PP P PS+ G PP P + P
Sbjct: 474 LTPSQRAEREAARAGPEGTSPPTPTPSTATG-GPPEDSPTVAP 515
Score = 59.3 bits (142), Expect = 8e-09
Identities = 63/213 (29%), Positives = 75/213 (35%), Gaps = 43/213 (20%)
Query: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPL-GIAPPPPTPRGPPPPGRGGPPP 369
EP+PPP Q P PP + S LPP PL G+ P R PPP PP
Sbjct: 2209 EPVPPPV------KQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPP-----PP 2257
Query: 370 PPPPATGRSGPLPPPPPG---------AGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALV 420
PP SGP PP +G P PPP P G P P
Sbjct: 2258 PPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVP--- 2314
Query: 421 PAGGLAPGG-GRGALLDQIRQGIQLNKTPGAP----------ESSALQP-----PPQSSE 464
GL GG R + +G+ PG P E S L P PPQ +
Sbjct: 2315 ---GLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPD 2371
Query: 465 GLVGALMHVMQKRSRAIHSSDEGEDQAGDEDED 497
G L+ SS E E + D+ E+
Sbjct: 2372 GPPDLLLESQWHHYSGEASSSEEEPPSPDDKEN 2404
Score = 53.5 bits (127), Expect = 4e-07
Identities = 48/142 (33%), Positives = 53/142 (37%), Gaps = 37/142 (26%)
Query: 309 RQEPLPPPPP------PSRGGNQLPRPPI--VGGNKGRSGPLPPVPLGIAPPPPTP---- 356
R+E LPP PP PS+G P P G G + + LG AP PP P
Sbjct: 2132 REESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPG-VRVLSLGPAPEPPKPATSK 2190
Query: 357 ----------------RGPPPPGRGGPPPPPP---PATGRSGPLPPPP-----PGAGGPP 392
G P P PP PP P S LPP P P G
Sbjct: 2191 IILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250
Query: 393 MPPPPPPPPPPPSSGNGPAPPP 414
PPPPPPP +GPA PP
Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPP 2272
Score = 47.8 bits (112), Expect = 2e-05
Identities = 41/122 (33%), Positives = 48/122 (39%), Gaps = 22/122 (18%)
Query: 314 PPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPP--PGRGGPP-PP 370
PPP P S G ++ P + PL V G P P +P P G P P
Sbjct: 1853 PPPAPRSFSGARIKVPNYSPSRR----PLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPA 1908
Query: 371 PPPATGRSGPLPP-PPPGA-GGPPMPPPPPPPPPPPSS-------------GNGPAPPPL 415
PP + R PL P PPP PP+ P PPP+S GPAP P
Sbjct: 1909 PPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968
Query: 416 PP 417
PP
Sbjct: 1969 PP 1970
Score = 46.6 bits (109), Expect = 5e-05
Identities = 96/414 (23%), Positives = 129/414 (31%), Gaps = 98/414 (23%)
Query: 161 PPPTPANEERRGGLPPL-PLHPGGDQGGPPVGPLSLGLATVDIQNPDITS-------SRY 212
PPP PA EE+ PP+ P +G PP+ P P+ TS +
Sbjct: 444 PPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTAT 503
Query: 213 RGLPAPGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVN-------NLDP 265
G P P+ A K + K I + + S S V P+ D + + P
Sbjct: 504 GGPPEDSPTVAPKSTTFLKNIRQFIMPVVSA--RSSRVIKTPRRFMDEDPPKPPKVEVSP 561
Query: 266 DLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLP--------PPP 317
LR + + + + L R+ + R+ PPP
Sbjct: 562 VLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPP 621
Query: 318 PPSRGGNQLPRPPIVGGNKGR--------------------SGPLPPVPLGIAPPPPTPR 357
PP+ P PP R L P PLG AP P P
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLG-APEAPEP- 679
Query: 358 GPPPPGRGGPPPPPPPATGRSGPLPPP---------------PPGA----GGP------- 391
PPP P P P A GR+ L P P GA GP
Sbjct: 680 -EPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
Query: 392 -------------PMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQI 438
+PPP P PPPS PPL A + G P G + +
Sbjct: 739 QPLQALQTQLLPQALPPPQPQLQPPPSP---QQMPPLEKARIAGVGSLPLSGVEEKMFSL 795
Query: 439 --RQGIQLNKTPGAPESSALQPPPQSSEG----LVGALMHVMQKRSRAIHSSDE 486
R +QL K + P S G + GA+ + + + S DE
Sbjct: 796 LKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDR--GPVRSEDE 847
Score = 44.7 bits (104), Expect = 2e-04
Identities = 51/173 (29%), Positives = 59/173 (34%), Gaps = 38/173 (21%)
Query: 295 EDQGGLEAVRQEMRR-QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPL----PPV-PLG 348
E+ LEA + P P PP L +V G R P+ PP+ P
Sbjct: 1790 EEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDS 1849
Query: 349 IAPPPPTPRG------------PPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPP 396
+ PPP PR P GG P P+ G L P G P P P
Sbjct: 1850 GSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAP 1909
Query: 397 PP--------PPPPPPSSGNGP---------APPP--LPPALVPAGG-LAPGG 429
P P PPPS P PPP + AL P G LAP G
Sbjct: 1910 PRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPG 1962
Score = 42.4 bits (98), Expect = 0.001
Identities = 87/341 (25%), Positives = 109/341 (31%), Gaps = 89/341 (26%)
Query: 163 PTPANEERRGGLPPLP---LHPGGDQGGPPVGPLSLGLATVDIQNPDITSSRYRGLPAPG 219
P P++E G PPL L PG + P+ L L PD S+
Sbjct: 1808 PAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPL------RPDSGSA--------- 1852
Query: 220 PSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLDPDLRSLFSRAGISEA 279
P PA + SG + V N P R L G+S
Sbjct: 1853 PPPAPRSFSGAR--------------------------IKVPNYSPSRRPL---GGVSFG 1883
Query: 280 QLTDAETSKLIYDFIEDQGGLE--AVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKG 337
L + + I G + A + RR PL P PPPSR + PP+ +
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWAS----PPLKTSPQL 1939
Query: 338 RSGP-------LPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRS-GPLPPPPPGAG 389
R P L P +APP P P PPP G +G S L G
Sbjct: 1940 RVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLG 1999
Query: 390 GPPMPPPPPPPPPPPSSGNGPAPPP------------LPPALVPAGGLAPGGGRGA---- 433
P SS GP P +V A GLAP GA
Sbjct: 2000 TEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIE 2059
Query: 434 LLDQIRQGIQLNKTPGAPESSALQPP-----PQSSEGLVGA 469
LD + G E+ A+Q P P S G+V A
Sbjct: 2060 QLDGVDDGTD-------SEAEAVQQPRGQGTPPSGPGVVRA 2093
Score = 40.8 bits (94), Expect = 0.003
Identities = 64/263 (24%), Positives = 88/263 (33%), Gaps = 71/263 (26%)
Query: 305 QEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLG-IAP-PPPTP---RG- 358
Q E + P S +Q R P G K ++ PLPP L +AP PP TP RG
Sbjct: 124 QGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTPPKTPARKRGE 183
Query: 359 --------------------PPPPGRGGPPPPPPPATGRSGPLPPPP---------PGAG 389
P R P P + GR P P
Sbjct: 184 EGTERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEA 243
Query: 390 GPPMPPPPPPPPPPP--------SSGNGPAPPPLPPALVPAGGLAPGGGRG--------- 432
+P P PPPP P GP P P P GG + GGRG
Sbjct: 244 AVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPR---RGGQSSRGGRGGRGRGRGGG 300
Query: 433 -------------ALLDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALMHVMQKRSR 479
+ Q+ G++ + G E S Q PQ G +K+ +
Sbjct: 301 LPFVIKFVSRAKKVKMGQLSLGLESGQGQGQHEES-WQDVPQRRVGSGQGGSPCWKKQEQ 359
Query: 480 AIHSSDEGEDQAGDEDEDDEWDD 502
+ DE E++ +E++D E ++
Sbjct: 360 KL--DDEEEEKKEEEEKDKEGEE 380
Score = 37.7 bits (86), Expect = 0.025
Identities = 46/170 (27%), Positives = 55/170 (32%), Gaps = 47/170 (27%)
Query: 310 QEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGP-- 367
Q+P PPS G + R ++G R+ P +P I G P G GP
Sbjct: 2076 QQPRGQGTPPSGPG--VVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE 2133
Query: 368 ---PPPPPPATGR-------SGPLPPPP-----PGAGGP------PMPPPPPPP------ 400
PP PP A G + P P PGA G P P PP P
Sbjct: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIIL 2193
Query: 401 ----------------PPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGAL 434
P PP P PP + P + L PG G L
Sbjct: 2194 VNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVL 2243
Score = 35.4 bits (80), Expect = 0.12
Identities = 40/137 (29%), Positives = 48/137 (35%), Gaps = 18/137 (13%)
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPP-----------PPSSGNGPAP 412
RG PP P R+G L GA G PP P P G GP
Sbjct: 2079 RGQGTPPSGPGVVRAGVL-----GAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPRE 2133
Query: 413 PPLPPALVPAGGLAPGGGRGAL-LDQIRQGIQLNKTPGAPESSALQPPPQSSEGLVGALM 471
LPPA A G P G A D R L PG S L P P+ + ++
Sbjct: 2134 ESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLS-LGPAPEPPKPATSKII 2192
Query: 472 HVMQKRSRAIHSSDEGE 488
V + + + EGE
Sbjct: 2193 LVNKLGQVFVKMAGEGE 2209
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 81.6 bits (200), Expect = 1e-15
Identities = 66/166 (39%), Positives = 71/166 (42%), Gaps = 49/166 (29%)
Query: 314 PPPPP------PSRGGNQLP----------RPPIVGGNKGRSGPLPP------VPLG--- 348
PPPPP P +GGNQ RPP GGN+ + P PP P G
Sbjct: 71 PPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQ 130
Query: 349 ---IAPPPPTPRGPPPPG----RGGPPPP-----PPPATG---RSGPLPP-----PPPGA 388
PPP P PPP G +G PP P PPP G RS PP PP
Sbjct: 131 SHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQE 190
Query: 389 GGPPMPPPPP--PPPPPPSSGNGPAPPPLPPALVPAG-GLAPGGGR 431
G P PPPP P PPP+ GN P P PPA P G P GGR
Sbjct: 191 GNKPQGPPPPGKPQGPPPAGGN-PQQPQAPPAGKPQGPPPPPQGGR 235
Score = 78.2 bits (191), Expect = 2e-14
Identities = 58/184 (31%), Positives = 68/184 (36%), Gaps = 39/184 (21%)
Query: 304 RQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPG 363
R+ +P PPPPP + PP GGN+ + P PP PP + PP
Sbjct: 39 RRPQGGNQPQRPPPPPGKPQG----PPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPP 94
Query: 364 RGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPP--------PPPPP-----PPPSSGN-G 409
G P PPP G PPPPG P PPP PPPPP PPP GN
Sbjct: 95 HPGKPERPPPQGGNQSQGTPPPPGK--PERPPPQGGNQSHRPPPPPGKPERPPPQGGNQS 152
Query: 410 PAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQ--------PPPQ 461
PPP PG G + + PG P+ Q PPP
Sbjct: 153 QGPPP-----------HPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPG 201
Query: 462 SSEG 465
+G
Sbjct: 202 KPQG 205
Score = 77.8 bits (190), Expect = 2e-14
Identities = 68/198 (34%), Positives = 76/198 (38%), Gaps = 40/198 (20%)
Query: 297 QGGLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGN-KGRSGPLPPVPLGIAPPPPT 355
QGG + R +P PPP +GGNQ PP G +GR G P P
Sbjct: 42 QGGNQPQRPPPPPGKPQGPPP---QGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGK 98
Query: 356 PRGPPPPG----RGGPPPP-----PPPATGRSGPLPPPPPGAGGPPMPPP--------PP 398
P PPP G +G PPPP PPP G PPPPPG P PPP PP
Sbjct: 99 PERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGK--PERPPPQGGNQSQGPP 156
Query: 399 PPP-----PPPSSGN----------GPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQ 443
P P PPP GN P PP P G PG +G Q
Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGP--PPAGGNPQ 214
Query: 444 LNKTPGAPESSALQPPPQ 461
+ P A + PPPQ
Sbjct: 215 QPQAPPAGKPQGPPPPPQ 232
Score = 76.6 bits (187), Expect = 5e-14
Identities = 51/120 (42%), Positives = 54/120 (45%), Gaps = 28/120 (23%)
Query: 314 PPPP-----PPSRGGNQLPRPPI----------VGGNKGRSGPLPPVPLGIAPPPPT--- 355
PPPP PP +GGNQ PP GNK RS PP G PP
Sbjct: 135 PPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPP---GKPQGPPQQEG 191
Query: 356 --PRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPP 413
P+GPPPPG+ P PPPA G P P P AG P PPPPP PP G PP
Sbjct: 192 NKPQGPPPPGK---PQGPPPAGGN--PQQPQAPPAGKPQGPPPPPQGGRPPRPAQGQQPP 246
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/130 (37%), Positives = 53/130 (40%), Gaps = 31/130 (23%)
Query: 356 PRGPPPPGRGGPPPPPPPATGRS-GPLPPPPPGAGGPPM-------PPPPP--PPPPPPS 405
P+ PPPP G P PPP +S GP PPP G PP PPP P P PPP
Sbjct: 47 PQRPPPPP-GKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQ 105
Query: 406 SGN---GPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTPGAPESSALQPPPQS 462
GN G PPP P P P GG Q + PG PE +PPPQ
Sbjct: 106 GGNQSQGTPPPPGKPERPP-----PQGG--------NQSHRPPPPPGKPE----RPPPQG 148
Query: 463 SEGLVGALMH 472
G H
Sbjct: 149 GNQSQGPPPH 158
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/257 (27%), Positives = 87/257 (33%), Gaps = 59/257 (22%)
Query: 152 QSGDRRQLPPPPT--PANEERRGGL----PPLPLHPGGDQGGPPVGPLSLGLATVDIQNP 205
Q G++ Q PPPP P +GG PP P PG +G PP G N
Sbjct: 42 QGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPP--PGKPEGRPPQGG-----------NQ 88
Query: 206 DITSSRYRGLPA-PGPSPADKKRSGKKKISKADIGAPSGFKHVSHVGWDPQNGFDVNNLD 264
+ G P P P ++ + K + P G SH P
Sbjct: 89 SQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQ-SHRPPPP---------- 137
Query: 265 PDLRSLFSRAGISEAQLTDAETSKLIYDFIEDQGGLEAVRQEMRRQEPLPPPPPPSRGGN 324
P G +++Q K E E + R P P PP + GN
Sbjct: 138 PGKPERPPPQGGNQSQGPPPHPGKP-----EGPPPQEGNKSRSARSPPGKPQGPPQQEGN 192
Query: 325 QLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPP 384
+ P+ P PPP P+GPPP G P PPA G PPP
Sbjct: 193 K-PQGP--------------------PPPGKPQGPPPAGGNPQQPQAPPAGKPQG--PPP 229
Query: 385 PPGAGGPPMPPPPPPPP 401
PP G PP P PP
Sbjct: 230 PPQGGRPPRPAQGQQPP 246
Score = 30.4 bits (67), Expect = 3.9
Identities = 18/44 (40%), Positives = 21/44 (47%), Gaps = 2/44 (4%)
Query: 151 RQSGDRRQLPPPP-TPANEERRGGLPPLP-LHPGGDQGGPPVGP 192
+Q G++ Q PPPP P GG P P P G GPP P
Sbjct: 188 QQEGNKPQGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPP 231
Score = 29.3 bits (64), Expect = 8.7
Identities = 19/48 (39%), Positives = 24/48 (50%), Gaps = 6/48 (12%)
Query: 147 KRNQRQSGDRRQLPPPPTPANEER---RGGLPPL--PLHPGGDQGGPP 189
+R Q G++ PPPP P ER +GG P HPG +G PP
Sbjct: 121 ERPPPQGGNQSHRPPPP-PGKPERPPPQGGNQSQGPPPHPGKPEGPPP 167
>gi|39812378 RAN binding protein 9 [Homo sapiens]
Length = 729
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/126 (39%), Positives = 56/126 (44%), Gaps = 18/126 (14%)
Query: 311 EPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPP------TPRGPPPPGR 364
+P PPPP + QL PP L PV + P PP +P G P G
Sbjct: 4 QPPPPPPQQQQQQQQLSPPP--------PAALAPVSGVVLPAPPAVSAGSSPAGSPGGGA 55
Query: 365 GGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPPLPPALVPAGG 424
GG A P PPPPP PP PPPPPPPPP S+ + PP PP L A G
Sbjct: 56 GGEGLGAAAAALLLHPPPPPPPATAAPP--PPPPPPPPPASAAAPASGPPAPPGL--AAG 111
Query: 425 LAPGGG 430
P GG
Sbjct: 112 PGPAGG 117
Score = 74.7 bits (182), Expect = 2e-13
Identities = 50/135 (37%), Positives = 58/135 (42%), Gaps = 28/135 (20%)
Query: 305 QEMRRQEPLPPPPPPSRG---GNQLPRPPIV----------GGNKGRSGPLPPVPLGIAP 351
Q+ ++Q+ L PPPP + G LP PP V GG G G +
Sbjct: 11 QQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALLLH 70
Query: 352 PPPTPRGPPPPGRGGPPPPPPPATGRSGPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPA 411
PPP PPPP PPPPPPP PPPP A P PP PP ++G GPA
Sbjct: 71 PPP----PPPPATAAPPPPPPP--------PPPPASAAA---PASGPPAPPGLAAGPGPA 115
Query: 412 PPPLPPALVPAGGLA 426
PALV A
Sbjct: 116 GGAPTPALVAGSSAA 130
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/167 (30%), Positives = 60/167 (35%), Gaps = 50/167 (29%)
Query: 365 GGPPPPPPPATGRSGPLPPPPPGA----GGPPMPPPP----------------------- 397
G PPPPPP + L PPPP A G +P PP
Sbjct: 3 GQPPPPPPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGA 62
Query: 398 --------PPPPPPPSSGNGPAPPPLPPALVPAGGLAPGGGRGALLDQIRQGIQLNKTP- 448
PPPPPPP++ P PPP PP PA AP G A G+ P
Sbjct: 63 AAAALLLHPPPPPPPATAAPPPPPPPPPP--PASAAAPASGPPA-----PPGLAAGPGPA 115
Query: 449 -GAPE------SSALQPPPQSSEGLVGALMHVMQKRSRAIHSSDEGE 488
GAP SSA P P L + ++ R + DE E
Sbjct: 116 GGAPTPALVAGSSAAAPFPHGDSALNEQEKELQRRLKRLYPAVDEQE 162
Score = 43.1 bits (100), Expect = 6e-04
Identities = 33/117 (28%), Positives = 39/117 (33%), Gaps = 42/117 (35%)
Query: 299 GLEAVRQEMRRQEPLPPPPPPSRGGNQLPRPPIVGGNKGRSGPLPPVPLGIAPPPPTPRG 358
GL A + P PPPP + APPPP
Sbjct: 59 GLGAAAAALLLHPPPPPPPATA-----------------------------APPPP---- 85
Query: 359 PPPPGRGGPPPPPPPATGRS-GPLPPPPPGAGGPPMPPPPPPPPPPPSSGNGPAPPP 414
PPPPPPPA+ + PP PPG P P P P + + AP P
Sbjct: 86 --------PPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFP 134
Score = 32.3 bits (72), Expect = 1.0
Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 5/52 (9%)
Query: 312 PLPPPPPPSRG---GNQLPRPPIVGGNKGRSG--PLPPVPLGIAPPPPTPRG 358
P PPPPPP+ + P PP + G +G P P + G + P P G
Sbjct: 85 PPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSSAAAPFPHG 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.139 0.439
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,715,410
Number of Sequences: 37866
Number of extensions: 3531292
Number of successful extensions: 138198
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2027
Number of HSP's successfully gapped in prelim test: 1646
Number of HSP's that attempted gapping in prelim test: 21291
Number of HSP's gapped (non-prelim): 35608
length of query: 502
length of database: 18,247,518
effective HSP length: 107
effective length of query: 395
effective length of database: 14,195,856
effective search space: 5607363120
effective search space used: 5607363120
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.