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Search of human proteins with 4507593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507593 tumor necrosis factor (ligand) superfamily, member
10 [Homo sapiens]
(281 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507593 tumor necrosis factor (ligand) superfamily, member 10... 573 e-164
gi|4507595 tumor necrosis factor ligand superfamily, member 11 i... 93 3e-19
gi|14790152 tumor necrosis factor ligand superfamily, member 11 ... 91 1e-18
gi|4557329 fas ligand [Homo sapiens] 66 4e-11
gi|23510445 tumor necrosis factor (ligand) superfamily, member 1... 60 2e-09
gi|25952144 tumor necrosis factor ligand superfamily, member 14 ... 57 2e-08
gi|25952147 tumor necrosis factor ligand superfamily, member 14 ... 55 7e-08
gi|4557433 CD40 ligand [Homo sapiens] 49 6e-06
gi|6806893 lymphotoxin alpha precursor [Homo sapiens] 46 3e-05
gi|229092381 lymphotoxin alpha precursor [Homo sapiens] 46 3e-05
gi|25952111 tumor necrosis factor alpha [Homo sapiens] 45 7e-05
gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens] 38 0.009
gi|4505035 lymphotoxin-beta isoform a [Homo sapiens] 37 0.015
gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens] 36 0.033
gi|224548983 tumor necrosis factor superfamily, member 13b isofo... 34 0.16
gi|5730097 tumor necrosis factor superfamily, member 13b isoform... 33 0.36
gi|4507597 tumor necrosis factor (ligand) superfamily, member 12... 32 0.62
gi|20070228 nucleobindin 1 [Homo sapiens] 30 2.4
gi|116517328 G-protein coupled receptor 115 [Homo sapiens] 30 3.1
gi|26051250 TNFSF12-TNFSF13 protein [Homo sapiens] 29 4.0
gi|222080109 orexin receptor 2 [Homo sapiens] 29 5.3
gi|168229156 NFKB activating protein [Homo sapiens] 28 6.9
gi|115527120 nebulin [Homo sapiens] 28 6.9
gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo sa... 28 6.9
gi|19923717 deltex 3-like [Homo sapiens] 28 6.9
gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo s... 28 9.0
gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo s... 28 9.0
gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo sa... 28 9.0
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 28 9.0
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 28 9.0
>gi|4507593 tumor necrosis factor (ligand) superfamily, member 10
[Homo sapiens]
Length = 281
Score = 573 bits (1478), Expect = e-164
Identities = 281/281 (100%), Positives = 281/281 (100%)
Query: 1 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE 60
MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE
Sbjct: 1 MAMMEVQGGPSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE 60
Query: 61 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ 120
DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ
Sbjct: 61 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQ 120
Query: 121 RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG 180
RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG
Sbjct: 121 RVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKG 180
Query: 181 FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY 240
FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY
Sbjct: 181 FYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLY 240
Query: 241 SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG 281
SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG
Sbjct: 241 SIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLVG 281
>gi|4507595 tumor necrosis factor ligand superfamily, member 11
isoform 1 [Homo sapiens]
Length = 317
Score = 92.8 bits (229), Expect = 3e-19
Identities = 70/284 (24%), Positives = 131/284 (46%), Gaps = 25/284 (8%)
Query: 10 PSLGQTCVLIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKE--------- 60
P+ ++ + ++ L Q +C + YF ++ ++ S+ G C +
Sbjct: 42 PAASRSMFVALLGLGLGQVVCSVALFFYFRAQMDP--NRISEDGTHCIYRILRLHENADF 99
Query: 61 DDSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPL---VRER 117
D+ + D + + C ++K + V+K + ++ + S L R +
Sbjct: 100 QDTTLESQDTKLIPDSCRRIKQAFQGAVQKELQHIVGSQHIRAEKAMVDGSWLDLAKRSK 159
Query: 118 GPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIH 177
+ AH+T N P+ ++ +L +SW R G + +SN+ NG+L+++
Sbjct: 160 LEAQPFAHLT-----INATDIPSGSHKVSL----SSWYHDR-GWAKISNMTFSNGKLIVN 209
Query: 178 EKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYT-SYPDPILLMKSARNSCWSKDAE 236
+ GFYY+Y+ FR E + Q++ Y+ K + P LMK WS ++E
Sbjct: 210 QDGFYYLYANICFRHHETSGDLATEYLQLMVYVTKTSIKIPSSHTLMKGGSTKYWSGNSE 269
Query: 237 YGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAFLV 280
+ YSI GG F+L+ + I + V+N L+D D +A++FGAF V
Sbjct: 270 FHFYSINVGGFFKLRSGEEISIEVSNPSLLDPDQDATYFGAFKV 313
>gi|14790152 tumor necrosis factor ligand superfamily, member 11
isoform 2 [Homo sapiens]
Length = 244
Score = 90.5 bits (223), Expect = 1e-18
Identities = 46/131 (35%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
Query: 151 INSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYI 210
++SW R G + +SN+ NG+L++++ GFYY+Y+ FR E + Q++ Y+
Sbjct: 111 LSSWYHDR-GWAKISNMTFSNGKLIVNQDGFYYLYANICFRHHETSGDLATEYLQLMVYV 169
Query: 211 YKYT-SYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMD 269
K + P LMK WS ++E+ YSI GG F+L+ + I + V+N L+D D
Sbjct: 170 TKTSIKIPSSHTLMKGGSTKYWSGNSEFHFYSINVGGFFKLRSGEEISIEVSNPSLLDPD 229
Query: 270 HEASFFGAFLV 280
+A++FGAF V
Sbjct: 230 QDATYFGAFKV 240
>gi|4557329 fas ligand [Homo sapiens]
Length = 281
Score = 65.9 bits (159), Expect = 4e-11
Identities = 51/185 (27%), Positives = 87/185 (47%), Gaps = 24/185 (12%)
Query: 95 TSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSW 154
TS+ ++ EKQ E+ R AH+TG +SN+ S P W
Sbjct: 118 TSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTG---KSNSRSMPLE------------W 162
Query: 155 ESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIY-KY 213
E + G LS + + G LVI+E G Y++YS+ YFR Q + N+ + +Y +
Sbjct: 163 EDTY-GIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQ------SCNNLPLSHKVYMRN 215
Query: 214 TSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHEAS 273
+ YP +++M+ S + + S Y G +F L D ++V+V+ L++ + +
Sbjct: 216 SKYPQDLVMMEGKMMS-YCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQT 274
Query: 274 FFGAF 278
FFG +
Sbjct: 275 FFGLY 279
>gi|23510445 tumor necrosis factor (ligand) superfamily, member 15
[Homo sapiens]
Length = 251
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/136 (34%), Positives = 72/136 (52%), Gaps = 12/136 (8%)
Query: 154 WESSRSGHSFLSN-LHLRNGELVIHEKGFYYIYSQTYFRFQ----EEIKENTKNDK--QM 206
WE G +F N ++ N L+I E G Y+IYSQ FR EI++ + +K +
Sbjct: 119 WEHEL-GLAFTKNRMNYTNKFLLIPESGDYFIYSQVTFRGMTSECSEIRQAGRPNKPDSI 177
Query: 207 VQYIYKYT-SYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHL 265
I K T SYP+P L+ ++ C + IY G +F L+E D++ V+V++ L
Sbjct: 178 TVVITKVTDSYPEPTQLLMGTKSVC--EVGSNWFQPIYLGAMFSLQEGDKLMVNVSDISL 235
Query: 266 IDMDHE-ASFFGAFLV 280
+D E +FFGAFL+
Sbjct: 236 VDYTKEDKTFFGAFLL 251
>gi|25952144 tumor necrosis factor ligand superfamily, member 14
isoform 1 precursor [Homo sapiens]
Length = 240
Score = 56.6 bits (135), Expect = 2e-08
Identities = 52/206 (25%), Positives = 94/206 (45%), Gaps = 29/206 (14%)
Query: 79 QVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSS 138
Q+ W+L ++V ++ + +QE++ + E P AAH+TG
Sbjct: 60 QLHWRLGEMVTRLPDGPAGSWEQLIQERRSH------EVNP---AAHLTGANSSLTGSGG 110
Query: 139 PNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKE 198
P WE+ + G +FL L +G LV+ + G+YYIYS+ +
Sbjct: 111 PLL------------WET-QLGLAFLRGLSYHDGALVVTKAGYYYIYSKVQL---GGVGC 154
Query: 199 NTKNDKQMVQYIYKYT-SYPDPILLMKSARNSCWSKDAEYGLY--SIYQGGIFELKENDR 255
+ +YK T YP+ + L+ S ++ C + ++ S + GG+ L+ ++
Sbjct: 155 PLGLASTITHGLYKRTPRYPEELELLVSQQSPCGRATSSSRVWWDSSFLGGVVHLEAGEK 214
Query: 256 IFVSVTNEHLIDM-DHEASFFGAFLV 280
+ V V +E L+ + D S+FGAF+V
Sbjct: 215 VVVRVLDERLVRLRDGTRSYFGAFMV 240
>gi|25952147 tumor necrosis factor ligand superfamily, member 14
isoform 2 [Homo sapiens]
Length = 204
Score = 55.1 bits (131), Expect = 7e-08
Identities = 48/174 (27%), Positives = 80/174 (45%), Gaps = 22/174 (12%)
Query: 113 LVRERGPQRV--AAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLR 170
L++ER V AAH+TG P WE+ + G +FL L
Sbjct: 47 LIQERRSHEVNPAAHLTGANSSLTGSGGPLL------------WET-QLGLAFLRGLSYH 93
Query: 171 NGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYT-SYPDPILLMKSARNS 229
+G LV+ + G+YYIYS+ + + +YK T YP+ + L+ S ++
Sbjct: 94 DGALVVTKAGYYYIYSKVQL---GGVGCPLGLASTITHGLYKRTPRYPEELELLVSQQSP 150
Query: 230 CWSKDAEYGLY--SIYQGGIFELKENDRIFVSVTNEHLIDM-DHEASFFGAFLV 280
C + ++ S + GG+ L+ + + V V +E L+ + D S+FGAF+V
Sbjct: 151 CGRATSSSRVWWDSSFLGGVVHLEAGEEVVVRVLDERLVRLRDGTRSYFGAFMV 204
>gi|4557433 CD40 ligand [Homo sapiens]
Length = 261
Score = 48.5 bits (114), Expect = 6e-06
Identities = 62/262 (23%), Positives = 115/262 (43%), Gaps = 34/262 (12%)
Query: 18 LIVIFTVLLQSLCVAVTYVYFTNELKQMQDKYSKSGIACFLKEDDSYWDPNDEESMNSPC 77
L+ +F ++ Q + A+ VY L +++D+ + F+K S+ + C
Sbjct: 27 LLTVF-LITQMIGSALFAVYLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLN-C 84
Query: 78 WQVKWQLRQLVRKMILRTSEETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLS 137
++K Q V+ ++L EET +K+ + ++ PQ +AAH+ +S
Sbjct: 85 EEIKSQFEGFVKDIMLN-KEET-----KKENSFEMQKGDQNPQ-IAAHV---------IS 128
Query: 138 SPNSKNEKALGRKINSWESSRSGHSFLSN--LHLRNG-ELVIHEKGFYYIYSQTYFRFQE 194
+SK L W + G+ +SN + L NG +L + +G YYIY+Q F
Sbjct: 129 EASSKTTSVL-----QW--AEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNR 181
Query: 195 EIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKEND 254
E + + + + +L+++A +K G SI+ GG+FEL+
Sbjct: 182 E----ASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPC--GQQSIHLGGVFELQPGA 235
Query: 255 RIFVSVTNEHLIDMDHEASFFG 276
+FV+VT+ + + FG
Sbjct: 236 SVFVNVTDPSQVSHGTGFTSFG 257
>gi|6806893 lymphotoxin alpha precursor [Homo sapiens]
Length = 205
Score = 46.2 bits (108), Expect = 3e-05
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 18/157 (11%)
Query: 123 AAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFY 182
AAH+ G + N+L W ++ L N L++ G Y
Sbjct: 64 AAHLIGDPSKQNSLL----------------WRANTDRAFLQDGFSLSNNSLLVPTSGIY 107
Query: 183 YIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTS-YPDPILLMKSARNSCWSKDAEYGLYS 241
++YSQ F + + T + + + ++S YP + L+ S++ + E L+S
Sbjct: 108 FVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLL-SSQKMVYPGLQEPWLHS 166
Query: 242 IYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAF 278
+Y G F+L + D++ + + FFGAF
Sbjct: 167 MYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAF 203
>gi|229092381 lymphotoxin alpha precursor [Homo sapiens]
Length = 205
Score = 46.2 bits (108), Expect = 3e-05
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 18/157 (11%)
Query: 123 AAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFY 182
AAH+ G + N+L W ++ L N L++ G Y
Sbjct: 64 AAHLIGDPSKQNSLL----------------WRANTDRAFLQDGFSLSNNSLLVPTSGIY 107
Query: 183 YIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTS-YPDPILLMKSARNSCWSKDAEYGLYS 241
++YSQ F + + T + + + ++S YP + L+ S++ + E L+S
Sbjct: 108 FVYSQVVFSGKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLL-SSQKMVYPGLQEPWLHS 166
Query: 242 IYQGGIFELKENDRIFVSVTNEHLIDMDHEASFFGAF 278
+Y G F+L + D++ + + FFGAF
Sbjct: 167 MYHGAAFQLTQGDQLSTHTDGIPHLVLSPSTVFFGAF 203
>gi|25952111 tumor necrosis factor alpha [Homo sapiens]
Length = 233
Score = 45.1 bits (105), Expect = 7e-05
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 3/126 (2%)
Query: 154 WESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKY 213
W + R+ + + LR+ +LV+ +G Y IYSQ F+ Q + + + Y
Sbjct: 104 WLNRRANALLANGVELRDNQLVVPSEGLYLIYSQVLFKGQGCPSTHVLLTHTISRIAVSY 163
Query: 214 TSYPDPILLMKS--ARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHLIDMDHE 271
+ + + +KS R + +A+ IY GG+F+L++ DR+ + +D
Sbjct: 164 QTKVNLLSAIKSPCQRETPEGAEAKPWYEPIYLGGVFQLEKGDRLSAEINRPDYLDFAES 223
Query: 272 AS-FFG 276
+FG
Sbjct: 224 GQVYFG 229
>gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens]
Length = 389
Score = 38.1 bits (87), Expect = 0.009
Identities = 36/136 (26%), Positives = 58/136 (42%), Gaps = 21/136 (15%)
Query: 148 GRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYF-RFQEEIKENTKNDKQM 206
G +N W S + + + LH R+GEL + G Y+IYSQ Y+ F + D++
Sbjct: 268 GGVLNDW-SRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVYYINFTDFASYEVVVDEK- 325
Query: 207 VQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEHL- 265
+ I K+ N+C Y G+ LK +I V + + +
Sbjct: 326 -----PFLQCTRSIETGKTNYNTC------------YTAGVCLLKARQKIAVKMVHADIS 368
Query: 266 IDMDHEASFFGAFLVG 281
I+M +FFGA +G
Sbjct: 369 INMSKHTTFFGAIRLG 384
>gi|4505035 lymphotoxin-beta isoform a [Homo sapiens]
Length = 244
Score = 37.4 bits (85), Expect = 0.015
Identities = 31/141 (21%), Positives = 60/141 (42%), Gaps = 13/141 (9%)
Query: 154 WESSRSGHSFLSNLHLRNGE-LVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYK 212
WE+++ S + E L + + G YY+Y +R + + +
Sbjct: 104 WETTKEQAFLTSGTQFSDAEGLALPQDGLYYLYCLVGYRGRAPPGGGDPQGRSVTLRSSL 163
Query: 213 YTSYP-----DPILLMKSARNSCWSKDAE----YG---LYSIYQGGIFELKENDRIFVSV 260
Y + P LL++ A D YG S+ GG+ +L+ +R++V++
Sbjct: 164 YRAGGAYGPGTPELLLEGAETVTPVLDPARRQGYGPLWYTSVGFGGLVQLRRGERVYVNI 223
Query: 261 TNEHLIDMDHEASFFGAFLVG 281
++ ++D +FFGA +VG
Sbjct: 224 SHPDMVDFARGKTFFGAVMVG 244
>gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens]
Length = 391
Score = 36.2 bits (82), Expect = 0.033
Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 23/138 (16%)
Query: 148 GRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQT---YFRFQEEIKENTKNDK 204
G +N W S + + + LH R+GEL + G Y+IYSQ Y F + D+
Sbjct: 268 GGVLNDW-SRITMNPKVFKLHPRSGELEVLVDGTYFIYSQVEVYYINFTDFASYEVVVDE 326
Query: 205 QMVQYIYKYTSYPDPILLMKSARNSCWSKDAEYGLYSIYQGGIFELKENDRIFVSVTNEH 264
+ + I K+ N+C Y G+ LK +I V + +
Sbjct: 327 K------PFLQCTRSIETGKTNYNTC------------YTAGVCLLKARQKIAVKMVHAD 368
Query: 265 L-IDMDHEASFFGAFLVG 281
+ I+M +FFGA +G
Sbjct: 369 ISINMSKHTTFFGAIRLG 386
>gi|224548983 tumor necrosis factor superfamily, member 13b isoform
2 [Homo sapiens]
Length = 266
Score = 33.9 bits (76), Expect = 0.16
Identities = 36/152 (23%), Positives = 68/152 (44%), Gaps = 25/152 (16%)
Query: 137 SSPNSKNEKALGRKINSWESSRSGHSFL---------SNLHLRNGELVIHEKGFYYIYSQ 187
SS NS+N++A+ ++F+ S L + ++++ E G+++IY Q
Sbjct: 125 SSQNSRNKRAV-----QGPEETGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQ 179
Query: 188 TYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAE-YGLYSIYQGG 246
+ + T ++Q K + D + L+ R C E S Y G
Sbjct: 180 VLY------TDKTYAMGHLIQR-KKVHVFGDELSLVTLFR--CIQNMPETLPNNSCYSAG 230
Query: 247 IFELKENDRIFVSVTNEHL-IDMDHEASFFGA 277
I +L+E D + +++ E+ I +D + +FFGA
Sbjct: 231 IAKLEEGDELQLAIPRENAQISLDGDVTFFGA 262
>gi|5730097 tumor necrosis factor superfamily, member 13b isoform 1
[Homo sapiens]
Length = 285
Score = 32.7 bits (73), Expect = 0.36
Identities = 29/115 (25%), Positives = 54/115 (46%), Gaps = 11/115 (9%)
Query: 165 SNLHLRNGELVIHEKGFYYIYSQTYFRFQEEIKENTKNDKQMVQYIYKYTSYPDPILLMK 224
S L + ++++ E G+++IY Q + + T ++Q K + D + L+
Sbjct: 176 SALEEKENKILVKETGYFFIYGQVLY------TDKTYAMGHLIQR-KKVHVFGDELSLVT 228
Query: 225 SARNSCWSKDAE-YGLYSIYQGGIFELKENDRIFVSVTNEHL-IDMDHEASFFGA 277
R C E S Y GI +L+E D + +++ E+ I +D + +FFGA
Sbjct: 229 LFR--CIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGA 281
>gi|4507597 tumor necrosis factor (ligand) superfamily, member 12
precursor [Homo sapiens]
Length = 249
Score = 32.0 bits (71), Expect = 0.62
Identities = 12/40 (30%), Positives = 21/40 (52%)
Query: 151 INSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQTYF 190
++ WE +R S + + GE ++ G YY+Y Q +F
Sbjct: 130 VSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHF 169
>gi|20070228 nucleobindin 1 [Homo sapiens]
Length = 461
Score = 30.0 bits (66), Expect = 2.4
Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 16/120 (13%)
Query: 55 ACFLKEDDSYWDPNDEESMNSPCWQVKWQLRQLVRKMI------LRTSEETISTVQEKQ- 107
A F KE + +DP +EE + + ++R+ V K + L T EE +++ Q K+
Sbjct: 267 ALFTKELEKVYDPKNEEDDMREMEEERLRMREHVMKNVDTNQDRLVTLEEFLASTQRKEF 326
Query: 108 ---------QNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSR 158
+ P E +R + N + S+ +ALGR E+ +
Sbjct: 327 GDTGEGWETVEMHPAYTEEELRRFEEELAAREAELNAKAQRLSQETEALGRSQGRLEAQK 386
>gi|116517328 G-protein coupled receptor 115 [Homo sapiens]
Length = 695
Score = 29.6 bits (65), Expect = 3.1
Identities = 33/123 (26%), Positives = 50/123 (40%), Gaps = 12/123 (9%)
Query: 95 TSEETISTVQEKQQNISP-----LVRER--GPQRVAAHITGTRGRSNTLSSPNSKNEKAL 147
T+ I+ + E +NIS + RE+ VA HI T SN PN L
Sbjct: 155 TTSGNIAFIVELLKNISTDLSDNVTREKMKSYSEVANHILDTAAISNWAFIPNKNASSDL 214
Query: 148 GRKINSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIY--SQTYFRFQEEIKENTKNDKQ 205
+ +N + H+ N+ EL I KGF+ + S+ F + T++
Sbjct: 215 LQSVNLFARQLHIHNNSENI---VNELFIQTKGFHINHNTSEKSLNFSMSMNNTTEDILG 271
Query: 206 MVQ 208
MVQ
Sbjct: 272 MVQ 274
>gi|26051250 TNFSF12-TNFSF13 protein [Homo sapiens]
Length = 330
Score = 29.3 bits (64), Expect = 4.0
Identities = 11/38 (28%), Positives = 20/38 (52%)
Query: 151 INSWESSRSGHSFLSNLHLRNGELVIHEKGFYYIYSQT 188
++ WE +R S + + GE ++ G YY+Y Q+
Sbjct: 130 VSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQS 167
>gi|222080109 orexin receptor 2 [Homo sapiens]
Length = 444
Score = 28.9 bits (63), Expect = 5.3
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 8/58 (13%)
Query: 86 QLVRKMILRTSEETISTVQEKQQNISPLVRERGP--------QRVAAHITGTRGRSNT 135
Q+ RK+ R T S VQ K + + P+ + RGP VAA I R R T
Sbjct: 245 QIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARRKT 302
>gi|168229156 NFKB activating protein [Homo sapiens]
Length = 415
Score = 28.5 bits (62), Expect = 6.9
Identities = 16/51 (31%), Positives = 23/51 (45%)
Query: 110 ISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESSRSG 160
++P+ R P R A+ G R S+ P+ GR+ S SRSG
Sbjct: 1 MAPVSGSRSPDREASGSGGRRRSSSKSPKPSKSARSPRGRRSRSHSCSRSG 51
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 28.5 bits (62), Expect = 6.9
Identities = 43/204 (21%), Positives = 84/204 (41%), Gaps = 28/204 (13%)
Query: 39 TNELKQMQDKYSKSGIACFLKED-DSYWDPNDEESMNSPCWQVKWQLRQLVRKMILRTSE 97
T+++K +D G CFL + D + + ++ + K + + K++L T E
Sbjct: 5086 TSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKVVLDTPE 5145
Query: 98 ETISTVQEKQQNISPLVRERGPQRVAAHITGTRGRSNTLSSPNSKNEKALGRKINSWESS 157
VQE + ++S LV ++ + T + L + G+K+ S
Sbjct: 5146 --YRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKR-------GQKLQS---- 5192
Query: 158 RSGHSFLSNLHLRNGELVIHEKGFYYIYSQTY-FRFQEEIKENTKNDKQMVQYIY---KY 213
L++ EL E+ ++ +QT + +++K+ K +QY KY
Sbjct: 5193 -------QYLYV---ELATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKY 5242
Query: 214 TSYPDPILLMKSARNSCWSKDAEY 237
T PD +L+++ R + D Y
Sbjct: 5243 TPVPDTPILIRAKRAYWNASDLRY 5266
>gi|89357935 deiodinase, iodothyronine, type I isoform c [Homo
sapiens]
Length = 201
Score = 28.5 bits (62), Expect = 6.9
Identities = 11/34 (32%), Positives = 20/34 (58%)
Query: 138 SPNSKNEKALGRKINSWESSRSGHSFLSNLHLRN 171
+PN + G++ N WE + G +F +N+ +RN
Sbjct: 92 APNCPVVRLSGQRCNIWEFMQDGWAFKNNMDIRN 125
>gi|19923717 deltex 3-like [Homo sapiens]
Length = 740
Score = 28.5 bits (62), Expect = 6.9
Identities = 20/81 (24%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 105 EKQQNISPLVRERGPQRVAAHITGTRGRS-----NTLSSPNSKNEKALGRKINSWESSRS 159
EK+ ++ ++E P V T +R + +S KN + L ++ S S+
Sbjct: 258 EKRFGVNIEIQESSPNMVCLDFTSSRSGDLEAARESFASEFQKNTEPLKQECVSLADSKQ 317
Query: 160 GHSFLSNLHLRNGELVIHEKG 180
+ F L+ + +L+I EKG
Sbjct: 318 ANKFKQELNHQFTKLLIKEKG 338
>gi|187829485 autism susceptibility candidate 2 isoform 3 [Homo
sapiens]
Length = 266
Score = 28.1 bits (61), Expect = 9.0
Identities = 11/36 (30%), Positives = 20/36 (55%)
Query: 201 KNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAE 236
+ND+ + Q++ K P + +K +NSC D+E
Sbjct: 153 ENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE 188
>gi|187829452 autism susceptibility candidate 2 isoform 2 [Homo
sapiens]
Length = 1235
Score = 28.1 bits (61), Expect = 9.0
Identities = 11/36 (30%), Positives = 20/36 (55%)
Query: 201 KNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAE 236
+ND+ + Q++ K P + +K +NSC D+E
Sbjct: 153 ENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE 188
>gi|17864090 autism susceptibility candidate 2 isoform 1 [Homo
sapiens]
Length = 1259
Score = 28.1 bits (61), Expect = 9.0
Identities = 11/36 (30%), Positives = 20/36 (55%)
Query: 201 KNDKQMVQYIYKYTSYPDPILLMKSARNSCWSKDAE 236
+ND+ + Q++ K P + +K +NSC D+E
Sbjct: 153 ENDRNLCQHLGKRKKMPKALRQLKPGQNSCRDSDSE 188
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 28.1 bits (61), Expect = 9.0
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 69 DEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNI----SPLVRERGPQRVAA 124
D+ S+++P ++K R+ +K+ S E IS +E + + S + +E+ +V
Sbjct: 1164 DKISLSAPAKKIKLN-RETGKKI---GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRR 1219
Query: 125 HITGTRGRSNTL 136
+TGT G S+TL
Sbjct: 1220 KVTGTEGSSSTL 1231
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 28.1 bits (61), Expect = 9.0
Identities = 21/72 (29%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 69 DEESMNSPCWQVKWQLRQLVRKMILRTSEETISTVQEKQQNI----SPLVRERGPQRVAA 124
D+ S+++P ++K R+ +K+ S E IS +E + + S + +E+ +V
Sbjct: 1198 DKISLSAPAKKIKLN-RETGKKI---GSTENISNTKEPSEKLESTSSKVKQEKVKGKVRR 1253
Query: 125 HITGTRGRSNTL 136
+TGT G S+TL
Sbjct: 1254 KVTGTEGSSSTL 1265
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,426,372
Number of Sequences: 37866
Number of extensions: 440249
Number of successful extensions: 1322
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 1292
Number of HSP's gapped (non-prelim): 35
length of query: 281
length of database: 18,247,518
effective HSP length: 101
effective length of query: 180
effective length of database: 14,423,052
effective search space: 2596149360
effective search space used: 2596149360
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.