Guide to the Human Genome
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Name: DIO1 Sequence: fasta or formatted (201aa) NCBI GI: 89357935
Description:

deiodinase, iodothyronine, type I isoform c

Referenced in:

Selenium Proteins
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [249aa] deiodinase, iodothyronine, type I isoform a
alt prot [185aa] deiodinase, iodothyronine, type I isoform b
alt prot [161aa] deiodinase, iodothyronine, type I isoform d
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.0         10           2
 C cysteine            1.5          3           1
 D aspartate           3.5          7           1
 E glutamate           5.0         10           2
 F phenylalanine       4.0          8           2
 G glycine             6.0         12           2
 H histidine           3.0          6           1
 I isoleucine          4.0          8           2
 K lysine              4.5          9           1
 L leucine            12.9         26           3
 M methionine          3.0          6           1
 N asparagine          6.0         12           2
 P proline             6.0         12           1
 Q glutamine           6.5         13           1
 R arginine            7.0         14           1
 S serine              4.0          8           2
 T threonine           3.5          7           2
 V valine              8.5         17           3
 W tryptophan          4.0          8           1
 Y tyrosine            2.5          5           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   deiodinase, iodothyronine, type I isoform c 
DIO1                  0.942   deiodinase, iodothyronine, type I isoform a 
DIO1                  0.606   deiodinase, iodothyronine, type I isoform b 
DIO1                  0.543   deiodinase, iodothyronine, type I isoform d 
DIO3                  0.128   deiodinase, iodothyronine, type III 
DIO2                  0.118   deiodinase, iodothyronine, type II isoform b 
DIO2                  0.118   deiodinase, iodothyronine, type II isoform a 
DIO2                  0.118   deiodinase, iodothyronine, type II isoform a 
ATP1A2                0.010   Na+/K+ -ATPase alpha 2 subunit proprotein 
TNFSF10               0.008   tumor necrosis factor (ligand) superfamily, member 10...
ATP1A3                0.008   Na+/K+ -ATPase alpha 3 subunit 
USP9Y                 0.008   ubiquitin specific protease 9, Y-linked 
USP9X                 0.008   ubiquitin specific protease 9, X-linked isoform 4 [...
USP9X                 0.008   ubiquitin specific protease 9, X-linked isoform 3 [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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