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Search of human proteins with 4507425
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507425 teratocarcinoma-derived growth factor 1 [Homo
sapiens]
(188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens] 410 e-115
gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens] 261 2e-70
gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens] 258 2e-69
gi|14211837 cryptic [Homo sapiens] 92 3e-19
gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens] 92 3e-19
gi|148833508 notch1 preproprotein [Homo sapiens] 47 7e-06
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens] 47 7e-06
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens] 45 3e-05
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 42 4e-04
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 42 4e-04
gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 42 4e-04
gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 42 4e-04
gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 42 4e-04
gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 42 4e-04
gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 42 4e-04
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 42 4e-04
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 40 0.001
gi|24430141 fibrillin 1 precursor [Homo sapiens] 40 0.002
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 39 0.002
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 39 0.003
gi|55770876 notch4 preproprotein [Homo sapiens] 39 0.003
gi|13449287 NG3 protein [Homo sapiens] 39 0.003
gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens] 39 0.003
gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens] 39 0.003
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 38 0.004
gi|134244285 Notch homolog 3 [Homo sapiens] 38 0.004
gi|24041035 notch 2 preproprotein [Homo sapiens] 38 0.004
gi|4504383 HGF activator preproprotein [Homo sapiens] 38 0.004
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens] 38 0.006
gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens] 38 0.006
>gi|4507425 teratocarcinoma-derived growth factor 1 [Homo sapiens]
Length = 188
Score = 410 bits (1053), Expect = e-115
Identities = 188/188 (100%), Positives = 188/188 (100%)
Query: 1 MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIR 60
MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIR
Sbjct: 1 MDCRKMARFSYSVIWIMAISKVFELGLVAGLGHQEFARPSRGYLAFRDDSIWPQEEPAIR 60
Query: 61 PRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPH 120
PRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPH
Sbjct: 61 PRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPH 120
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGI 180
DTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGI
Sbjct: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVMDEHLVASRTPELPPSARTTTFMLVGI 180
Query: 181 CLSIQSYY 188
CLSIQSYY
Sbjct: 181 CLSIQSYY 188
>gi|169163540 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 261 bits (668), Expect = 2e-70
Identities = 121/139 (87%), Positives = 124/139 (89%)
Query: 35 EFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSF 94
E +R G LAFRDDSI PQEEPAIRPRSSQ VPPMGIQ SKE NRTCCLNGGTCMLGSF
Sbjct: 54 EVSRVKEGDLAFRDDSIQPQEEPAIRPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSF 113
Query: 95 CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVM 154
CAC PSFYG NCEH VRKENCGSVPHDT LPKKCS+CKCWHGQLRCFPQAFLPGCDGLVM
Sbjct: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVM 173
Query: 155 DEHLVASRTPELPPSARTT 173
DEHL+A RTPELPPSA TT
Sbjct: 174 DEHLMAPRTPELPPSACTT 192
>gi|169164915 PREDICTED: similar to hCG1644233 [Homo sapiens]
Length = 195
Score = 258 bits (660), Expect = 2e-69
Identities = 120/139 (86%), Positives = 123/139 (88%)
Query: 35 EFARPSRGYLAFRDDSIWPQEEPAIRPRSSQRVPPMGIQHSKELNRTCCLNGGTCMLGSF 94
E +R G LAFRDDSI PQEEPAI PRSSQ VPPMGIQ SKE NRTCCLNGGTCMLGSF
Sbjct: 54 EVSRVKEGDLAFRDDSIQPQEEPAICPRSSQLVPPMGIQDSKEPNRTCCLNGGTCMLGSF 113
Query: 95 CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFPQAFLPGCDGLVM 154
CAC PSFYG NCEH VRKENCGSVPHDT LPKKCS+CKCWHGQLRCFPQAFLPGCDGLVM
Sbjct: 114 CACLPSFYGWNCEHGVRKENCGSVPHDTRLPKKCSMCKCWHGQLRCFPQAFLPGCDGLVM 173
Query: 155 DEHLVASRTPELPPSARTT 173
DEHL+A RTPELPPSA TT
Sbjct: 174 DEHLMAPRTPELPPSACTT 192
>gi|14211837 cryptic [Homo sapiens]
Length = 223
Score = 91.7 bits (226), Expect = 3e-19
Identities = 36/69 (52%), Positives = 42/69 (60%)
Query: 82 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF 141
CC NGGTC+LGSFC CP F GR CEHD R+ CG++ H W + C LC+C G L C
Sbjct: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
Query: 142 PQAFLPGCD 150
P CD
Sbjct: 150 PLQTPDRCD 158
>gi|118600995 cripto, FRL-1, cryptic family 1B [Homo sapiens]
Length = 223
Score = 91.7 bits (226), Expect = 3e-19
Identities = 36/69 (52%), Positives = 42/69 (60%)
Query: 82 CCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCF 141
CC NGGTC+LGSFC CP F GR CEHD R+ CG++ H W + C LC+C G L C
Sbjct: 90 CCRNGGTCVLGSFCVCPAHFTGRYCEHDQRRSECGALEHGAWTLRACHLCRCIFGALHCL 149
Query: 142 PQAFLPGCD 150
P CD
Sbjct: 150 PLQTPDRCD 158
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 47.4 bits (111), Expect = 7e-06
Identities = 33/87 (37%), Positives = 42/87 (48%), Gaps = 16/87 (18%)
Query: 74 HSKELNRTCCLNGGTCMLG--SF-CACPPSFYGRNCEHDVRKENCGSVP--HDTWLPKKC 128
++ + + C NGGTC+ G SF C CPP F G C+HDV + C S P H
Sbjct: 983 NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE--CDSQPCLHG------- 1033
Query: 129 SLCKCWHGQLRC-FPQAFL-PGCDGLV 153
C+ G RC PQ + P C LV
Sbjct: 1034 GTCQDGCGSYRCTCPQGYTGPNCQNLV 1060
Score = 44.3 bits (103), Expect = 6e-05
Identities = 28/80 (35%), Positives = 37/80 (46%), Gaps = 15/80 (18%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKC--------SLC 131
C N GTC+ +G + C CPP F G CE DV + C S P D + C C
Sbjct: 1238 CFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNE--CLSNPCDARGTQNCVQRVNDFHCEC 1295
Query: 132 KCWHGQLRCFPQAFLPGCDG 151
+ H RC ++ + GC G
Sbjct: 1296 RAGHTGRRC--ESVINGCKG 1313
Score = 40.4 bits (93), Expect = 0.001
Identities = 24/65 (36%), Positives = 29/65 (44%), Gaps = 8/65 (12%)
Query: 83 CLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C NGG C+ C CPPSF+G C DV + CG P L + C G R
Sbjct: 149 CANGGQCLPFEASYICHCPPSFHGPTCRQDVNE--CGQKP---GLCRHGGTCHNEVGSYR 203
Query: 140 CFPQA 144
C +A
Sbjct: 204 CVCRA 208
Score = 39.7 bits (91), Expect = 0.002
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 8/42 (19%)
Query: 83 CLNGGTCMLGS------FCACPPSFYGRNCEHDVRKENCGSV 118
C NGGTC + S C CP F G CE+D R CGS+
Sbjct: 1316 CKNGGTCAVASNTARGFICKCPAGFEGATCENDAR--TCGSL 1355
Score = 36.2 bits (82), Expect = 0.017
Identities = 18/40 (45%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCMLG---SFCACPPSFYGRNCEHDVRKENCGSVP 119
C NGG+C G +FC C P F G CE D+ + C S P
Sbjct: 916 CHNGGSCTDGINTAFCDCLPGFRGTFCEEDINE--CASDP 953
Score = 35.0 bits (79), Expect = 0.038
Identities = 15/32 (46%), Positives = 19/32 (59%), Gaps = 4/32 (12%)
Query: 83 CLNGGTCM----LGSFCACPPSFYGRNCEHDV 110
C NGGTC + CAC P F G+NCE ++
Sbjct: 227 CQNGGTCRPTGDVTHECACLPGFTGQNCEENI 258
Score = 34.3 bits (77), Expect = 0.065
Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 8/61 (13%)
Query: 83 CLNGGTCMLGSF---CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C NGG C+ G C CPP + G+ C DV + C +P+ + C HG
Sbjct: 266 CKNGGACVDGVNTYNCRCPPEWTGQYCTEDV--DECQLMPNAC---QNGGTCHNTHGGYN 320
Query: 140 C 140
C
Sbjct: 321 C 321
Score = 34.3 bits (77), Expect = 0.065
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
Query: 74 HSKELNRTCCLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVP 119
++ E C+NGGTC G C C F G NC+ ++ + C S P
Sbjct: 753 NNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINE--CASNP 799
Score = 34.3 bits (77), Expect = 0.065
Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 12/71 (16%)
Query: 83 CLNGGTCMLG----SF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQ 137
C NGG C SF C CP + G+ CE D+ + H + C+ HG
Sbjct: 838 CRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHG-------ASCQNTHGG 890
Query: 138 LRCFPQAFLPG 148
RC QA G
Sbjct: 891 YRCHCQAGYSG 901
Score = 33.9 bits (76), Expect = 0.085
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 14/65 (21%)
Query: 83 CLNGGTCMLGSF----CACPPSFYGRNCEHDVRKENCGSVP---HDTWLPKKCS-LCKC- 133
C NGGTC L + C CPP + G++C+ + + C S P LP + S +C C
Sbjct: 111 CRNGGTCDLLTLTEYKCRCPPGWSGKSCQ---QADPCASNPCANGGQCLPFEASYICHCP 167
Query: 134 --WHG 136
+HG
Sbjct: 168 PSFHG 172
Score = 33.5 bits (75), Expect = 0.11
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
CL+ G C+ + F C CP F G C++DV + C S P
Sbjct: 499 CLHNGRCLDKINEFQCECPTGFTGHLCQYDV--DECASTP 536
Score = 31.2 bits (69), Expect = 0.55
Identities = 18/47 (38%), Positives = 20/47 (42%), Gaps = 7/47 (14%)
Query: 80 RTC----CLNGGTCMLG---SFCACPPSFYGRNCEHDVRKENCGSVP 119
RTC CLNGGTC+ G C C F G C+ G P
Sbjct: 1350 RTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPCLGGNP 1396
Score = 30.8 bits (68), Expect = 0.72
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C N TC+ +G F C C P + G +CE V + C S P
Sbjct: 461 CQNDATCLDQIGEFQCICMPGYEGVHCE--VNTDECASSP 498
Score = 29.6 bits (65), Expect = 1.6
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 77 ELNRTCCLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
E + + C NG TC LG + C C ++G NC ++ + C S P
Sbjct: 1148 ECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEI--DECLSHP 1191
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/68 (27%), Positives = 30/68 (44%), Gaps = 9/68 (13%)
Query: 77 ELNRTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP--HDTWLPKKCS-- 129
+L C NGGTC G C C + G +C ++ ++C S H + +
Sbjct: 300 QLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI--DDCASAACFHGATCHDRVASF 357
Query: 130 LCKCWHGQ 137
C+C HG+
Sbjct: 358 YCECPHGR 365
Score = 28.9 bits (63), Expect = 2.7
Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 4/53 (7%)
Query: 69 PMGIQHSKELNRTCCLNGGT--CMLGSFCACPPSFYGRNCEHDVRKENCGSVP 119
P + E N C++G + G C C P + G NC D+ C S P
Sbjct: 711 PTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC--DINNNECESNP 761
Score = 28.1 bits (61), Expect = 4.7
Identities = 12/31 (38%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDV 110
C +G +C G C C + GRNCE D+
Sbjct: 878 CRHGASCQNTHGGYRCHCQAGYSGRNCETDI 908
Score = 27.7 bits (60), Expect = 6.1
Identities = 23/73 (31%), Positives = 34/73 (46%), Gaps = 13/73 (17%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C + G C+ LGSF C C + G CE DV + C S P + + C G+ +
Sbjct: 423 CEHAGKCINTLGSFECQCLQGYTGPRCEIDVNE--CVSNP-----CQNDATCLDQIGEFQ 475
Query: 140 CFPQAFLPGCDGL 152
C +PG +G+
Sbjct: 476 CI---CMPGYEGV 485
Score = 27.7 bits (60), Expect = 6.1
Identities = 13/37 (35%), Positives = 17/37 (45%), Gaps = 3/37 (8%)
Query: 77 ELNRTCCLNGGTCMLGS---FCACPPSFYGRNCEHDV 110
E T C NG C+ G C C + G +CE D+
Sbjct: 531 ECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI 567
>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
Length = 379
Score = 47.4 bits (111), Expect = 7e-06
Identities = 21/49 (42%), Positives = 27/49 (55%), Gaps = 7/49 (14%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHD---TWLPKKC 128
C+NGG C+ FC CPP FYG NC+ K NC + + + P KC
Sbjct: 218 CMNGGLCVTPGFCICPPGFYGVNCD----KANCSTTCFNGGTCFYPGKC 262
Score = 43.5 bits (101), Expect = 1e-04
Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 2/79 (2%)
Query: 71 GIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSL 130
G+ K T C NGGTC C CPP G CE + C + KC
Sbjct: 238 GVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCIG-KSKCKC 296
Query: 131 CKCWHGQLRCFPQAFLPGC 149
K + G L C PGC
Sbjct: 297 SKGYQGDL-CSKPVCEPGC 314
Score = 40.8 bits (94), Expect = 7e-04
Identities = 21/56 (37%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT-WLPKKCSLCKCWHGQ 137
C NGG C+ S C C + G C V + CG+ H T P KC + WHG+
Sbjct: 282 CRNGGKCIGKSKCKCSKGYQGDLCSKPVCEPGCGA--HGTCHEPNKCQCQEGWHGR 335
Score = 33.9 bits (76), Expect = 0.085
Identities = 13/33 (39%), Positives = 16/33 (48%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENC 115
C NGG C C CP F+G +CE + C
Sbjct: 186 CRNGGFCNERRICECPDGFHGPHCEKALCTPRC 218
>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
Length = 4349
Score = 45.4 bits (106), Expect = 3e-05
Identities = 26/70 (37%), Positives = 32/70 (45%), Gaps = 10/70 (14%)
Query: 74 HSKELNRTCCLNGGTCM----LGSFCACPPSFYGRNCEHDVRKENCGSVP----HDTWLP 125
HS ++ CLNGG C G C CPP F G++CE +ENC P L
Sbjct: 3947 HSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQG--RENCTFAPCLEGGTCILS 4004
Query: 126 KKCSLCKCWH 135
K + C C H
Sbjct: 4005 PKGASCNCPH 4014
Score = 36.2 bits (82), Expect = 0.017
Identities = 18/51 (35%), Positives = 25/51 (49%), Gaps = 7/51 (13%)
Query: 68 PPMGIQHSKELNRTC----CLNGGTCML---GSFCACPPSFYGRNCEHDVR 111
P +H ++ C CL GGTC+L G+ C CP + G CE + R
Sbjct: 3976 PQFSGKHCEQGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEAR 4026
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 41.6 bits (96), Expect = 4e-04
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 59 IRPRSSQRVPPMG-IQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGS 117
I+P Q +P G +E C +GGTC+ G+ C CP F G CE V +C +
Sbjct: 1341 IKPNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNRHCEN 1400
Query: 118 VPHDTWLPKKCSLCKCWHG 136
P C W+G
Sbjct: 1401 -GGQCLTPDICQCKPGWYG 1418
Score = 40.0 bits (92), Expect = 0.001
Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 2/79 (2%)
Query: 71 GIQHSKELNRTCCLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSL 130
G + K + C+NGG C+ S C+CP + G+ C + + C + + P C
Sbjct: 1482 GRRFQKSICDPTCMNGGKCVGPSTCSCPSGWSGKRCNTPICLQKCKN-GGECIAPSICHC 1540
Query: 131 CKCWHGQLRCFPQAFLPGC 149
W G +RC P C
Sbjct: 1541 PSSWEG-VRCQIPICNPKC 1558
Score = 37.7 bits (86), Expect = 0.006
Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 4/54 (7%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
CLNGG+C + C CP F+G +C++ C + H + ++C C G
Sbjct: 1430 CLNGGSCNKPNTCLCPNGFFGEHCQNAFCHPPCKNGGH----CMRNNVCVCREG 1479
Score = 33.9 bits (76), Expect = 0.085
Identities = 20/67 (29%), Positives = 26/67 (38%), Gaps = 2/67 (2%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFP 142
C NGG CM + C C + GR + + C + P CS W G+ RC
Sbjct: 1462 CKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCMNGGKCVG-PSTCSCPSGWSGK-RCNT 1519
Query: 143 QAFLPGC 149
L C
Sbjct: 1520 PICLQKC 1526
Score = 33.5 bits (75), Expect = 0.11
Identities = 11/24 (45%), Positives = 13/24 (54%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNC 106
C NGG C+ C C P +YG C
Sbjct: 1398 CENGGQCLTPDICQCKPGWYGPTC 1421
Score = 32.7 bits (73), Expect = 0.19
Identities = 19/46 (41%), Positives = 23/46 (50%), Gaps = 11/46 (23%)
Query: 83 CLNGGTCML------GS---FCACPPSFYGRNCEHDVRKENCGSVP 119
CLNGG+C+ GS C C P F+G CE D+ C S P
Sbjct: 1183 CLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDI--SGCQSNP 1226
Score = 32.0 bits (71), Expect = 0.32
Identities = 16/67 (23%), Positives = 25/67 (37%), Gaps = 2/67 (2%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFP 142
C C+ + C C P + G NC+ + +C + H + C HG C
Sbjct: 1302 CGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKN--HGKCIKPNICQCLPGHGGATCDE 1359
Query: 143 QAFLPGC 149
+ P C
Sbjct: 1360 EHCNPPC 1366
Score = 30.0 bits (66), Expect = 1.2
Identities = 10/29 (34%), Positives = 16/29 (55%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVR 111
CL GG C+ + C+C + G CE ++
Sbjct: 1558 CLYGGRCIFPNVCSCRTEYSGVKCEKKIQ 1586
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/46 (36%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKC 128
C GGTC+ + C CP F G +CE D+ + C H W C
Sbjct: 523 CRYGGTCVAPNKCVCPSGFTGSHCEKDI--DECALRTHTCWNDSAC 566
>gi|223029476 NEL-like protein 2 isoform d [Homo sapiens]
Length = 839
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT 122
C NGG C+ + CACP F G +CE D+ + + G V D+
Sbjct: 552 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDS 591
Score = 32.7 bits (73), Expect = 0.19
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 80 RTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHD--TWLPK--KCSLCK 132
R C N C G C CP +G+NC D + G V H+ W+ + +CS+C
Sbjct: 633 RHSCANDTICFNLDGGYDCRCP---HGKNCTGDCIHD--GKVKHNGQIWVLENDRCSVCS 687
Query: 133 CWHGQLRC 140
C +G + C
Sbjct: 688 CQNGFVMC 695
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLP----GCDGLVMDEHLVASRTPELPPSARTTTFM 176
DTW+ + C C+C G++ C+P LP C+ ++ E+ R P A T
Sbjct: 736 DTWV-QNCQQCRCLQGEVDCWP---LPCPDVECEFSILPENECCPRCVTDPCQADTIRND 791
Query: 177 LVGICL 182
+ CL
Sbjct: 792 ITKTCL 797
>gi|223029474 NEL-like protein 2 isoform c [Homo sapiens]
Length = 815
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT 122
C NGG C+ + CACP F G +CE D+ + + G V D+
Sbjct: 528 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDS 567
Score = 32.7 bits (73), Expect = 0.19
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 80 RTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHD--TWLPK--KCSLCK 132
R C N C G C CP +G+NC D + G V H+ W+ + +CS+C
Sbjct: 609 RHSCANDTICFNLDGGYDCRCP---HGKNCTGDCIHD--GKVKHNGQIWVLENDRCSVCS 663
Query: 133 CWHGQLRC 140
C +G + C
Sbjct: 664 CQNGFVMC 671
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLP----GCDGLVMDEHLVASRTPELPPSARTTTFM 176
DTW+ + C C+C G++ C+P LP C+ ++ E+ R P A T
Sbjct: 712 DTWV-QNCQQCRCLQGEVDCWP---LPCPDVECEFSILPENECCPRCVTDPCQADTIRND 767
Query: 177 LVGICL 182
+ CL
Sbjct: 768 ITKTCL 773
>gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT 122
C NGG C+ + CACP F G +CE D+ + + G V D+
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDS 568
Score = 32.7 bits (73), Expect = 0.19
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 80 RTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHD--TWLPK--KCSLCK 132
R C N C G C CP +G+NC D + G V H+ W+ + +CS+C
Sbjct: 610 RHSCANDTICFNLDGGYDCRCP---HGKNCTGDCIHD--GKVKHNGQIWVLENDRCSVCS 664
Query: 133 CWHGQLRC 140
C +G + C
Sbjct: 665 CQNGFVMC 672
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLP----GCDGLVMDEHLVASRTPELPPSARTTTFM 176
DTW+ + C C+C G++ C+P LP C+ ++ E+ R P A T
Sbjct: 713 DTWV-QNCQQCRCLQGEVDCWP---LPCPDVECEFSILPENECCPRCVTDPCQADTIRND 768
Query: 177 LVGICL 182
+ CL
Sbjct: 769 ITKTCL 774
>gi|223029470 NEL-like protein 2 isoform a [Homo sapiens]
Length = 866
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT 122
C NGG C+ + CACP F G +CE D+ + + G V D+
Sbjct: 579 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDS 618
Score = 32.7 bits (73), Expect = 0.19
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 80 RTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHD--TWLPK--KCSLCK 132
R C N C G C CP +G+NC D + G V H+ W+ + +CS+C
Sbjct: 660 RHSCANDTICFNLDGGYDCRCP---HGKNCTGDCIHD--GKVKHNGQIWVLENDRCSVCS 714
Query: 133 CWHGQLRC 140
C +G + C
Sbjct: 715 CQNGFVMC 722
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLP----GCDGLVMDEHLVASRTPELPPSARTTTFM 176
DTW+ + C C+C G++ C+P LP C+ ++ E+ R P A T
Sbjct: 763 DTWV-QNCQQCRCLQGEVDCWP---LPCPDVECEFSILPENECCPRCVTDPCQADTIRND 818
Query: 177 LVGICL 182
+ CL
Sbjct: 819 ITKTCL 824
>gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens]
Length = 816
Score = 41.6 bits (96), Expect = 4e-04
Identities = 17/40 (42%), Positives = 24/40 (60%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDT 122
C NGG C+ + CACP F G +CE D+ + + G V D+
Sbjct: 529 CRNGGACIAANVCACPQGFTGPSCETDIDECSDGFVQCDS 568
Score = 32.7 bits (73), Expect = 0.19
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 12/68 (17%)
Query: 80 RTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHD--TWLPK--KCSLCK 132
R C N C G C CP +G+NC D + G V H+ W+ + +CS+C
Sbjct: 610 RHSCANDTICFNLDGGYDCRCP---HGKNCTGDCIHD--GKVKHNGQIWVLENDRCSVCS 664
Query: 133 CWHGQLRC 140
C +G + C
Sbjct: 665 CQNGFVMC 672
Score = 29.3 bits (64), Expect = 2.1
Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 8/66 (12%)
Query: 121 DTWLPKKCSLCKCWHGQLRCFPQAFLP----GCDGLVMDEHLVASRTPELPPSARTTTFM 176
DTW+ + C C+C G++ C+P LP C+ ++ E+ R P A T
Sbjct: 713 DTWV-QNCQQCRCLQGEVDCWP---LPCPDVECEFSILPENECCPRCVTDPCQADTIRND 768
Query: 177 LVGICL 182
+ CL
Sbjct: 769 ITKTCL 774
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 41.6 bits (96), Expect = 4e-04
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 75 SKELNRTCCLNGGTCMLGSF--CACPPSFYGRNCEHDVR--KENCGSVPHDTWLPKKCSL 130
S E + + C +GG C+ GS C CPP F G C++DV + + G H L
Sbjct: 125 SAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYL 184
Query: 131 CKCWHG 136
C+C G
Sbjct: 185 CECKPG 190
Score = 40.8 bits (94), Expect = 7e-04
Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 24/86 (27%)
Query: 83 CLNGGTC-MLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCS------------ 129
C NGGTC + C CPP G NCE + C + KKC+
Sbjct: 570 CQNGGTCDSVTGACRCPPGVSGTNCE-----DGCPKGYYGKHCRKKCNCANRGRCHRLYG 624
Query: 130 LCKCWHG------QLRCFPQAFLPGC 149
C C G L C P AF PGC
Sbjct: 625 ACLCDPGLYGRFCHLTCPPWAFGPGC 650
Score = 39.3 bits (90), Expect = 0.002
Identities = 33/98 (33%), Positives = 46/98 (46%), Gaps = 16/98 (16%)
Query: 46 FRDDSIWPQEEPA-IRPRSS--QRVPPMGIQHSKELNRTC--CLNGGTCMLG-SFCACPP 99
F+DD + EE A +R + ++ + + + TC C NGGTC+LG C CP
Sbjct: 485 FQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPE 544
Query: 100 SFYGRNCEHDVRKENCGSVPHDTWLPKKCSL-CKCWHG 136
+ G C E C P DT+ K CS C C +G
Sbjct: 545 GWTGLIC-----NETC---PPDTF-GKNCSFSCSCQNG 573
Score = 36.2 bits (82), Expect = 0.017
Identities = 28/107 (26%), Positives = 42/107 (39%), Gaps = 23/107 (21%)
Query: 61 PRSSQRVPPMGIQHSKELNRTC-CLNGGTC------------MLGSFC--ACPPSFYGRN 105
PR ++ P H+ ++ C C NG +C +G C ACP YG N
Sbjct: 984 PRCAETCPAHTYGHN--CSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDN 1041
Query: 106 CEHDVRKENCGSVPHDTWLPKKCSLCKCWHG---QLRCFPQAFLPGC 149
C H +N G+ + C+ + W G + C P+ GC
Sbjct: 1042 CRHSCLCQNGGTCDP---VSGHCACPEGWAGLACEKECLPRDVRAGC 1085
Score = 35.8 bits (81), Expect = 0.022
Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 15/88 (17%)
Query: 80 RTCCLNGGTCM-LGSFCACPPSFYGRNCEHDVRK----ENC-------GSVPHDTWLPKK 127
R C G C + C CPP F G CE E+C G P
Sbjct: 1131 RCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGT 1190
Query: 128 CSLCKCWHG---QLRCFPQAFLPGCDGL 152
CS +HG Q RC P + PGC+ L
Sbjct: 1191 CSCAAGYHGPSCQQRCPPGRYGPGCEQL 1218
Score = 35.0 bits (79), Expect = 0.038
Identities = 29/93 (31%), Positives = 32/93 (34%), Gaps = 17/93 (18%)
Query: 74 HSKELNRTC-CLNGGTC-MLGSFCACPPSFYGRNCEHDVR--------KENCGSV-PHDT 122
+ K + C C N G C L C C P YGR C E C V PH
Sbjct: 603 YGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQ 662
Query: 123 WLPKKCSLCKCWHG------QLRCFPQAFLPGC 149
K+ C C G Q C F PGC
Sbjct: 663 SCDKRDGSCSCKAGFRGERCQAECELGYFGPGC 695
Score = 34.7 bits (78), Expect = 0.050
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 12/78 (15%)
Query: 61 PRSSQRVPPMGIQHSKELNRTC-CLNGGTCMLGS-FCACPPSFYGRNCEHDVRKENCGSV 118
P QR PP ++ + C CLNGG+C + C CP F G +C +
Sbjct: 1200 PSCQQRCPPG--RYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL--------TC 1249
Query: 119 PHDTWLPKKCSLCKCWHG 136
P + P +C C G
Sbjct: 1250 PQGRFGPNCTHVCGCGQG 1267
Score = 32.3 bits (72), Expect = 0.25
Identities = 20/55 (36%), Positives = 22/55 (40%), Gaps = 9/55 (16%)
Query: 83 CLNGGTCMLGS-FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
C N TC + C C P FYG+ CEH C H LC C HG
Sbjct: 1350 CHNNSTCEPATGTCRCGPGFYGQACEHP-----CPPGFHGAGCQ---GLCWCQHG 1396
Score = 30.8 bits (68), Expect = 0.72
Identities = 32/111 (28%), Positives = 41/111 (36%), Gaps = 21/111 (18%)
Query: 65 QRVPPMGIQHSKELNRTCCLNGGTCMLGS-FCACPPSFYGRNCEHDVRKENCGSVPHDTW 123
Q V P G R C N G C + C+C P + G +C+ R + G D
Sbjct: 814 QDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQ---RACDTGHWGPDCS 870
Query: 124 LPKKCS-----------LCKCWHGQL--RCFPQA----FLPGCDGLVMDEH 157
P CS LC C G + RC Q F PGC+ +H
Sbjct: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQH 921
Score = 30.4 bits (67), Expect = 0.94
Identities = 30/98 (30%), Positives = 36/98 (36%), Gaps = 27/98 (27%)
Query: 81 TC-CLNGGTC------------MLGSFC--ACPPSFYGRNCEHDVRKENCGSVPHDTWLP 125
TC C NGG C G C ACPP YG C + C + T P
Sbjct: 1304 TCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLE-----CSCHNNSTCEP 1358
Query: 126 KKCSLCKC---WHGQL---RCFPQAFLPGCDGLVMDEH 157
C+C ++GQ C P GC GL +H
Sbjct: 1359 -ATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQH 1395
Score = 28.1 bits (61), Expect = 4.7
Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 13/76 (17%)
Query: 81 TCCLNGGTCM-LGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
+C G C + C CPP G +CE D P W +C R
Sbjct: 743 SCSCGGAPCHGVTGQCRCPPGRTGEDCEAD--------CPEGRWGLGCQEICPACQHAAR 794
Query: 140 CFPQA----FLPGCDG 151
C P+ LPG G
Sbjct: 795 CDPETGACLCLPGFVG 810
Score = 27.7 bits (60), Expect = 6.1
Identities = 20/68 (29%), Positives = 25/68 (36%), Gaps = 8/68 (11%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCG-SVPHDTWLPKKCSLCKCW------- 134
C TC +G C G+ C + E+CG P T+ S C C
Sbjct: 695 CWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGV 754
Query: 135 HGQLRCFP 142
GQ RC P
Sbjct: 755 TGQCRCPP 762
Score = 27.7 bits (60), Expect = 6.1
Identities = 16/51 (31%), Positives = 21/51 (41%), Gaps = 2/51 (3%)
Query: 59 IRPRSSQRVPPMGIQHSKELNRTCCLNGGTC-MLGSFCACPPSFYGRNCEH 108
+ PR Q+ P E R C +G C + C CP + G CEH
Sbjct: 896 VGPRCEQQCPQGHFGPGCE-QRCQCQHGAACDHVSGACTCPAGWRGTFCEH 945
Score = 27.3 bits (59), Expect = 7.9
Identities = 30/110 (27%), Positives = 37/110 (33%), Gaps = 24/110 (21%)
Query: 80 RTCCLNGGTC-MLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSL-CKCW--- 134
R C G C + C CPP G C D R+ G C+L C C
Sbjct: 1433 RCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFG---------PSCTLHCDCGGGA 1483
Query: 135 -----HGQLRCFPQAFLPGC-DG----LVMDEHLVASRTPELPPSARTTT 174
GQ C P C +G L + L LP S+R T+
Sbjct: 1484 DCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTS 1533
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 40.0 bits (92), Expect = 0.001
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 18/84 (21%)
Query: 77 ELNRTCCLNGGTCMLGS----FCACPPSFYGRNCEHDVRKENCGSVP--HDTWLPKKCS- 129
ELN CLNGG C+ G C C P F G+ CE ++ + C S P H +
Sbjct: 1125 ELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE--CSSSPCLHGADCEDHING 1182
Query: 130 -LCKC---WHG-----QLRCFPQA 144
+CKC W G +L C P +
Sbjct: 1183 YVCKCQPGWSGHHCENELECIPNS 1206
Score = 32.7 bits (73), Expect = 0.19
Identities = 15/33 (45%), Positives = 19/33 (57%), Gaps = 3/33 (9%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRK 112
C N GTC+ + FC C P ++G CE DV K
Sbjct: 937 CKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNK 969
Score = 31.6 bits (70), Expect = 0.42
Identities = 20/61 (32%), Positives = 32/61 (52%), Gaps = 8/61 (13%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKEN-CGSVPHDTWLPKKCS--LCKCWHG 136
C N GTC+ + FC CP + G+ C+ + N CG+ T +PK + +C C +G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGN--GATCVPKSGTDIVCLCPYG 2401
Query: 137 Q 137
+
Sbjct: 2402 R 2402
Score = 30.4 bits (67), Expect = 0.94
Identities = 13/33 (39%), Positives = 16/33 (48%), Gaps = 4/33 (12%)
Query: 83 CLNGGTCML----GSFCACPPSFYGRNCEHDVR 111
C N TC+ C C F G+NCE DV+
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVK 892
Score = 30.0 bits (66), Expect = 1.2
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 8/35 (22%)
Query: 83 CLNGGTC--------MLGSFCACPPSFYGRNCEHD 109
C NGGTC ++ C CP F GR CE D
Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 29.6 bits (65), Expect = 1.6
Identities = 19/69 (27%), Positives = 33/69 (47%), Gaps = 9/69 (13%)
Query: 73 QHSKELNRTCCLNGGTC--MLGSF-CACPPSFYGRNCEHDVRK---ENC--GSVPHDTWL 124
Q S E C N TC + S+ C C + G+NC ++ + + C G + H++ +
Sbjct: 770 QESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDPCMNGGLCHESTI 829
Query: 125 PKKCSLCKC 133
P + +C C
Sbjct: 830 PGQ-FVCLC 837
Score = 28.9 bits (63), Expect = 2.7
Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 5/29 (17%)
Query: 83 CLNGGTC----MLGSF-CACPPSFYGRNC 106
C+NGG C + G F C CPP + G+ C
Sbjct: 818 CMNGGLCHESTIPGQFVCLCPPLYTGQFC 846
Score = 28.5 bits (62), Expect = 3.6
Identities = 20/85 (23%), Positives = 34/85 (40%), Gaps = 25/85 (29%)
Query: 68 PPMGIQHSKELNRTC---CLNGGTCM--------LGSFCACPPSFYGRNCE--------H 108
PP ++ +EL+ C N G+C+ C C P F G+NC H
Sbjct: 204 PPFSGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPH 263
Query: 109 DVRKENCGSVPHDTWLPKKCSLCKC 133
NC ++ +++ +C+C
Sbjct: 264 VCFHGNCSNITSNSF------ICEC 282
Score = 28.5 bits (62), Expect = 3.6
Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 7/72 (9%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C+N G C G C CP + G CE + +NC ++ + +C G
Sbjct: 1088 CMNEGFCQKSAHGFTCICPRGYTGAYCEKSI--DNCAEPELNSVICLNGGICV--DGPGH 1143
Query: 140 CFPQAFLPGCDG 151
F LPG G
Sbjct: 1144 TFDCRCLPGFSG 1155
Score = 27.3 bits (59), Expect = 7.9
Identities = 20/78 (25%), Positives = 26/78 (33%), Gaps = 26/78 (33%)
Query: 83 CLNGGTCML-----------------GSFCACPPSFYGRNCEHDVRKENC-------GSV 118
C NG TC+ G C C P + G CE D+ ++C S
Sbjct: 690 CKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDI--DDCILNACEHNST 747
Query: 119 PHDTWLPKKCSLCKCWHG 136
D L +C W G
Sbjct: 748 CKDLHLSYQCVCLSDWEG 765
Score = 27.3 bits (59), Expect = 7.9
Identities = 20/68 (29%), Positives = 27/68 (39%), Gaps = 17/68 (25%)
Query: 70 MGIQHSKELNRTCCLNGGTCM---LGSFCACPPSFYGRNC---------EHD-----VRK 112
+G H+ + C NGGTC+ +C C + G C EHD R
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 113 ENCGSVPH 120
C S+PH
Sbjct: 2666 ATCISLPH 2673
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 39.7 bits (91), Expect = 0.002
Identities = 17/36 (47%), Positives = 20/36 (55%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSV 118
CLNGG C+ + CAC F G CE D R C +V
Sbjct: 154 CLNGGRCVAPNRCACTYGFTGPQCERDYRTGPCFTV 189
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 39.3 bits (90), Expect = 0.002
Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 12/86 (13%)
Query: 74 HSKELNRTCCLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVP------HDTWL 124
H + R C +GGTC G C CP F GR CE + C S P T L
Sbjct: 440 HVSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDL 499
Query: 125 PKKCSLCKCWHGQL--RC-FPQAFLP 147
+C C +G + RC FP P
Sbjct: 500 STDTFVCNCPYGFVGSRCEFPVGLPP 525
Score = 38.5 bits (88), Expect = 0.003
Identities = 16/35 (45%), Positives = 20/35 (57%), Gaps = 3/35 (8%)
Query: 77 ELNRTCCLNGGTCML---GSFCACPPSFYGRNCEH 108
E + C NGG+C G C CPP +YG +CEH
Sbjct: 327 ECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEH 361
Score = 36.2 bits (82), Expect = 0.017
Identities = 18/42 (42%), Positives = 21/42 (50%), Gaps = 7/42 (16%)
Query: 83 CLNGGTCM-----LGSFCACPPSFYGRNCEHDVRKENCGSVP 119
C NGG+C C CPP+F G NCE V + C S P
Sbjct: 371 CFNGGSCRERNQGANYACECPPNFTGSNCEKKV--DRCTSNP 410
Score = 30.8 bits (68), Expect = 0.72
Identities = 22/75 (29%), Positives = 27/75 (36%), Gaps = 9/75 (12%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCE---HDVRKENC--GSVPHDTWLPKKCSLCKCW 134
C NGG C+ C C P F G CE D + C G HD C+ C
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCT-CPAG 469
Query: 135 HGQLRCFPQAFLPGC 149
RC + + C
Sbjct: 470 FSGRRCEVRTSIDAC 484
Score = 28.1 bits (61), Expect = 4.7
Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 7/59 (11%)
Query: 83 CLNG-----GTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
CL+G G C + C C P + GR C + C T P +C+ + W G
Sbjct: 222 CLSGCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCST--PWQCTCDEGWGG 278
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 38.9 bits (89), Expect = 0.003
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 10/61 (16%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C +GGTC ++G F C+CP F GR CE D+ + C P K ++C+ + G
Sbjct: 3871 CHSGGTCHNLVGGFSCSCPDGFTGRACERDINE--CLQSP-----CKNGAICQNFPGSFN 3923
Query: 140 C 140
C
Sbjct: 3924 C 3924
Score = 32.3 bits (72), Expect = 0.25
Identities = 12/28 (42%), Positives = 17/28 (60%), Gaps = 3/28 (10%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCE 107
C NGG+C G +C CP +G++CE
Sbjct: 3947 CFNGGSCQSGVDSYYCHCPFGVFGKHCE 3974
Score = 31.2 bits (69), Expect = 0.55
Identities = 14/29 (48%), Positives = 16/29 (55%), Gaps = 4/29 (13%)
Query: 83 CLNGGTCMLGSF----CACPPSFYGRNCE 107
C NGG+C G C+CP S GR CE
Sbjct: 4435 CQNGGSCEPGLHSGFTCSCPDSHTGRTCE 4463
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 38.5 bits (88), Expect = 0.003
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 11/67 (16%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP---HDTWLPKKCSL-CKCWH 135
C NG TCM G C C P + G+NC ++ + C S P H T PK C C
Sbjct: 939 CQNGATCMAQPSGYLCQCAPGYDGQNCSKEL--DACQSQPCHNHGTCTPKPGGFHCACPP 996
Query: 136 G--QLRC 140
G LRC
Sbjct: 997 GFVGLRC 1003
Score = 38.1 bits (87), Expect = 0.004
Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 13/76 (17%)
Query: 75 SKELNRTC----CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP-HDTWLPK 126
SKEL+ C C N GTC G CACPP F G CE DV + C P H T
Sbjct: 966 SKELD-ACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDV--DECLDQPCHPTGTAA 1022
Query: 127 KCSLCKCWHGQLRCFP 142
SL ++ Q C P
Sbjct: 1023 CHSLANAFYCQ--CLP 1036
Score = 37.0 bits (84), Expect = 0.010
Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 9/42 (21%)
Query: 83 CLNGGTCMLGS-------FCACPPSFYGRNCEHDVRKENCGS 117
C NGGTC L C CPP F G +CE V +NC S
Sbjct: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE--VNPDNCVS 282
Score = 36.2 bits (82), Expect = 0.017
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 7/46 (15%)
Query: 83 CLNGGTCMLGSF----CACPPSFYGRNCEHDVRK--ENCGSVPHDT 122
C+NGG C L ++ C CPP F G CE DV + ++ G P T
Sbjct: 165 CVNGGVC-LATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGT 209
Score = 35.4 bits (80), Expect = 0.029
Identities = 26/76 (34%), Positives = 28/76 (36%), Gaps = 25/76 (32%)
Query: 83 CLNGGTCM------LGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
C +GGTC LG C CP F G C H R +CG C HG
Sbjct: 1055 CFHGGTCEATAGSPLGFICHCPKGFEGPTCSH--RAPSCG-------------FHHCHHG 1099
Query: 137 QLRCFPQ---AFLPGC 149
L C P F P C
Sbjct: 1100 GL-CLPSPKPGFPPRC 1114
Score = 35.0 bits (79), Expect = 0.038
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP 119
CLNGG+C G +C CPPS G C+ + C S P
Sbjct: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQ--TSTDYCVSAP 775
Score = 33.5 bits (75), Expect = 0.11
Identities = 27/84 (32%), Positives = 33/84 (39%), Gaps = 13/84 (15%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C G TC+ L +F C CPP G+ CE V C S P C H L
Sbjct: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCE--VETNECASAP--------CLNHADCHDLLN 533
Query: 140 CFPQAFLPGCDGLVMDEHLVASRT 163
F LPG G +E + R+
Sbjct: 534 GFQCICLPGFSGTRCEEDIDECRS 557
Score = 33.1 bits (74), Expect = 0.14
Identities = 16/41 (39%), Positives = 20/41 (48%), Gaps = 3/41 (7%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVPH 120
C NGGTC G C CP ++ G +C DV + PH
Sbjct: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH 325
Score = 33.1 bits (74), Expect = 0.14
Identities = 15/30 (50%), Positives = 19/30 (63%), Gaps = 3/30 (10%)
Query: 83 CLNGGTCML--GSF-CACPPSFYGRNCEHD 109
C +GG+C+ GSF C CPP + G CE D
Sbjct: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCEAD 475
Score = 32.3 bits (72), Expect = 0.25
Identities = 17/40 (42%), Positives = 19/40 (47%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVP 119
C NGG C+ FC CPP F G C+ V C S P
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP--CESRP 938
Score = 31.6 bits (70), Expect = 0.42
Identities = 13/29 (44%), Positives = 15/29 (51%), Gaps = 4/29 (13%)
Query: 83 CLNGGTCMLGSF----CACPPSFYGRNCE 107
C NGGTC+ S C C P F G C+
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
Score = 31.6 bits (70), Expect = 0.42
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
CLN C +L F C C P F G CE D+ + C S P
Sbjct: 522 CLNHADCHDLLNGFQCICLPGFSGTRCEEDI--DECRSSP 559
Score = 31.2 bits (69), Expect = 0.55
Identities = 17/40 (42%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C NGGTC+ G+F C C F G CE +R +C P
Sbjct: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-PSCADSP 814
Score = 30.0 bits (66), Expect = 1.2
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 77 ELNRTCCLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
E + C NGG C G+F C C P F G C+ +V + C S P
Sbjct: 554 ECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--DECLSDP 597
>gi|13449287 NG3 protein [Homo sapiens]
Length = 293
Score = 38.5 bits (88), Expect = 0.003
Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 21/93 (22%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLRCFP 142
CLNGG C+ C C P + G++C DV + C + S+ C H CF
Sbjct: 118 CLNGGVCVRPDQCECAPGWGGKHCHVDV--DEC-----------RTSITLCSH---HCFN 161
Query: 143 QA--FLPGCDG---LVMDEHLVASRTPELPPSA 170
A F GC L +D +PE P SA
Sbjct: 162 TAGSFTCGCPHDLVLGVDGRTCMEGSPEPPTSA 194
>gi|41393583 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 38.5 bits (88), Expect = 0.003
Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 6/58 (10%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENC----GSVPHDTWLPKKCSLCKCWHG 136
C NGG+C+ C CP + G C+ DV + C G P C+CW G
Sbjct: 111 CRNGGSCVQPGRCRCPAGWRGDTCQSDV--DECSARRGGCPQRCVNTAGSYWCQCWEG 166
>gi|7705889 EGF-like-domain, multiple 7 [Homo sapiens]
Length = 273
Score = 38.5 bits (88), Expect = 0.003
Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 6/58 (10%)
Query: 83 CLNGGTCMLGSFCACPPSFYGRNCEHDVRKENC----GSVPHDTWLPKKCSLCKCWHG 136
C NGG+C+ C CP + G C+ DV + C G P C+CW G
Sbjct: 111 CRNGGSCVQPGRCRCPAGWRGDTCQSDV--DECSARRGGCPQRCVNTAGSYWCQCWEG 166
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 38.1 bits (87), Expect = 0.004
Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 22/113 (19%)
Query: 33 HQEFARPSRGYLAF-RDDS---IWPQEEPAIRP-RSSQRVPPMGIQ------HS---KEL 78
H F R +R Y RD+ I+ Q + +RP S RV HS K
Sbjct: 27 HARFRRGARSYQVICRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSC 86
Query: 79 NRTCCLNGGTCMLGSF-----CACPPSFYGRNCEHDVRK---ENCGSVPHDTW 123
+ C NGGTC + C CP F G+ CE D R E+ G TW
Sbjct: 87 SEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTW 139
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 38.1 bits (87), Expect = 0.004
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 83 CLNGGTC---MLGSFCACPPSFYGRNCEHDVRKENCGSVP 119
C +GGTC M G C C P + G NCE DV + C S P
Sbjct: 1093 CQHGGTCRGYMGGYMCECLPGYNGDNCEDDV--DECASQP 1130
Score = 37.7 bits (86), Expect = 0.006
Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 16/74 (21%)
Query: 73 QHSKELNRTCCLNGGTCMLG--SF-CACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKC- 128
Q + + + C NGGTC+ G SF C C P + G +C+H+ D L + C
Sbjct: 923 QDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA----------DPCLSRPCL 972
Query: 129 --SLCKCWHGQLRC 140
+C H RC
Sbjct: 973 HGGVCSAAHPGFRC 986
Score = 37.4 bits (85), Expect = 0.008
Identities = 17/38 (44%), Positives = 23/38 (60%), Gaps = 3/38 (7%)
Query: 79 NRTCCLNGGTCM-LGSFCACPPSFYGRNCEHDVRKENC 115
+R C NGG C+ G++C CPP + GR C D+R C
Sbjct: 1005 SRQPCQNGGRCVQTGAYCLCPPGWSGRLC--DIRSLPC 1040
Score = 37.4 bits (85), Expect = 0.008
Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 3/38 (7%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRKENCGS 117
CL+ GTC ++G F C CPP + G CE D+ + G+
Sbjct: 1176 CLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGA 1213
Score = 37.0 bits (84), Expect = 0.010
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 5/46 (10%)
Query: 77 ELNRTCCLNGGTC---MLGSFCACPPSFYGRNCEHDVRKENCGSVP 119
E + C+NGG C + G C CP F G C+ DV + C S P
Sbjct: 472 ECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDV--DECASTP 515
Score = 37.0 bits (84), Expect = 0.010
Identities = 20/40 (50%), Positives = 24/40 (60%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
CLNGG+C +GSF C+C P F G C DV + C S P
Sbjct: 858 CLNGGSCQDGVGSFSCSCLPGFAGPRCARDV--DECLSNP 895
Score = 35.8 bits (81), Expect = 0.022
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 83 CLNGGTCMLGSF---CACPPSFYGRNCEHDV 110
CLNGGTC+ G C CPP + G+ C DV
Sbjct: 245 CLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV 275
Score = 35.0 bits (79), Expect = 0.038
Identities = 17/32 (53%), Positives = 19/32 (59%), Gaps = 4/32 (12%)
Query: 83 CLNGGTCM----LGSFCACPPSFYGRNCEHDV 110
C NGGTC L CAC P F G+NCE +V
Sbjct: 206 CRNGGTCRQSGDLTYDCACLPGFEGQNCEVNV 237
Score = 34.7 bits (78), Expect = 0.050
Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 4/32 (12%)
Query: 83 CLNGGTCMLGS----FCACPPSFYGRNCEHDV 110
C +G C +G C+CPP + GR+C DV
Sbjct: 128 CAHGARCSVGPDGRFLCSCPPGYQGRSCRSDV 159
Score = 33.9 bits (76), Expect = 0.085
Identities = 14/28 (50%), Positives = 15/28 (53%), Gaps = 3/28 (10%)
Query: 83 CLNGGTCM---LGSFCACPPSFYGRNCE 107
C GGTC +G C CPP GR CE
Sbjct: 743 CRAGGTCSSDGMGFHCTCPPGVQGRQCE 770
Score = 30.8 bits (68), Expect = 0.72
Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVP 119
C +GG+C+ C+CPP G CE + +++CG P
Sbjct: 1131 CQHGGSCIDLVARYLCSCPPGTLGVLCE--INEDDCGPGP 1168
Score = 30.0 bits (66), Expect = 1.2
Identities = 11/27 (40%), Positives = 16/27 (59%)
Query: 93 SFCACPPSFYGRNCEHDVRKENCGSVP 119
+ C CPP F G C+ DV + + G+ P
Sbjct: 375 AICTCPPGFTGGACDQDVDECSIGANP 401
Score = 29.6 bits (65), Expect = 1.6
Identities = 16/63 (25%), Positives = 24/63 (38%), Gaps = 18/63 (28%)
Query: 77 ELNRTCCLNGGTC---MLGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKC 133
+L C NGGTC + G C C + G +C ++ C+ C
Sbjct: 279 QLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI---------------DDCATAVC 323
Query: 134 WHG 136
+HG
Sbjct: 324 FHG 326
Score = 29.3 bits (64), Expect = 2.1
Identities = 14/29 (48%), Positives = 18/29 (62%), Gaps = 3/29 (10%)
Query: 83 CLNGGTCML--GSF-CACPPSFYGRNCEH 108
C +GGTC+ GSF C CP + G CE+
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Score = 28.5 bits (62), Expect = 3.6
Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 4/34 (11%)
Query: 78 LNRTCCLNGGTCML----GSFCACPPSFYGRNCE 107
L+ + C NGG C + C CPP + G C+
Sbjct: 44 LDGSPCANGGRCTQLPSREAACLCPPGWVGERCQ 77
Score = 28.5 bits (62), Expect = 3.6
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C N TC+ +G F C C F G CE D+ + C S P
Sbjct: 440 CRNQATCLDRIGQFTCICMAGFTGTYCEVDI--DECQSSP 477
Score = 28.5 bits (62), Expect = 3.6
Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 3/27 (11%)
Query: 87 GTCM--LGSF-CACPPSFYGRNCEHDV 110
GTC + SF C CPP + G +CE D+
Sbjct: 899 GTCTDHVASFTCTCPPGYGGFHCEQDL 925
Score = 27.7 bits (60), Expect = 6.1
Identities = 20/60 (33%), Positives = 26/60 (43%), Gaps = 10/60 (16%)
Query: 69 PMGIQHSK-ELNRTC----CLNGGTCMLGS----FCACPPSFYGRNCEHDVRKENCGSVP 119
P G+Q + EL C C +GG C C+CP + G C+ DV E G P
Sbjct: 761 PPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV-DECAGPAP 819
Score = 27.7 bits (60), Expect = 6.1
Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 19/75 (25%)
Query: 83 CLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKC---SLCKCWHG 136
C GG C+ +C CP G +CE +V D L + C C+ + G
Sbjct: 1055 CQAGGQCVDEDSSHYCVCPEGRTGSHCEQEV----------DPCLAQPCQHGGTCRGYMG 1104
Query: 137 QLRCFPQAFLPGCDG 151
C LPG +G
Sbjct: 1105 GYMC---ECLPGYNG 1116
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 38.1 bits (87), Expect = 0.004
Identities = 16/39 (41%), Positives = 19/39 (48%), Gaps = 6/39 (15%)
Query: 83 CLNGGTCMLGS------FCACPPSFYGRNCEHDVRKENC 115
CLNGGTC + S C CPP F G C+ + C
Sbjct: 1313 CLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKC 1351
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 5/46 (10%)
Query: 77 ELNRTCCLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
E + C NGGTC+ + SF C CP F G C H++ + C S P
Sbjct: 990 ECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINE--CSSHP 1033
Score = 36.6 bits (83), Expect = 0.013
Identities = 16/33 (48%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRK 112
CLNGG CM +G + C C P F G CE D+ +
Sbjct: 1235 CLNGGQCMDRIGGYSCRCLPGFAGERCEGDINE 1267
Score = 35.4 bits (80), Expect = 0.029
Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 5/41 (12%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRKENCGSVPH 120
C NGGTC ++ F C+CPP G CE ++ ++C PH
Sbjct: 1196 CQNGGTCIDLVNHFKCSCPPGTRGLLCEENI--DDCARGPH 1234
Score = 34.7 bits (78), Expect = 0.050
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDV 110
C+N G C GS+ C CPP F G +CE D+
Sbjct: 882 CMNHGLCHNTQGSYMCECPPGFSGMDCEEDI 912
Score = 34.3 bits (77), Expect = 0.065
Identities = 26/75 (34%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP---HDTWLPKKC-SLCKCWH 135
CLN GTC+ LG++ C+CP + G+NC+ V C P T + KK S C C
Sbjct: 1034 CLNEGTCVDGLGTYRCSCPLGYTGKNCQTLVNL--CSRSPCKNKGTCVQKKAESQCLCPS 1091
Query: 136 GQLRCFPQAFLPGCD 150
G + CD
Sbjct: 1092 GWAGAYCDVPNVSCD 1106
Score = 33.5 bits (75), Expect = 0.11
Identities = 23/60 (38%), Positives = 27/60 (45%), Gaps = 10/60 (16%)
Query: 61 PRSSQRVPPMGI--QHSKELNRTC----CLNGGTC-MLGSF---CACPPSFYGRNCEHDV 110
P S Q P G Q+ L C C+NGGTC G F C C P F G CE ++
Sbjct: 202 PGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNI 261
Score = 33.5 bits (75), Expect = 0.11
Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C+N G C+ + F C CPP F G C+ D+ ++C S P
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI--DDCSSTP 540
Score = 33.1 bits (74), Expect = 0.14
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 13/61 (21%)
Query: 73 QHSKELNRTCCLNGGTC----MLG-SFCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKK 127
QH + C NGGTC MLG + C C F G +C++ S H ++ +
Sbjct: 63 QHRDPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQY--------STSHPCFVSRP 114
Query: 128 C 128
C
Sbjct: 115 C 115
Score = 32.3 bits (72), Expect = 0.25
Identities = 17/40 (42%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 83 CLNGGTC---MLGSFCACPPSFYGRNCEHDVRKENCGSVP 119
C NGGTC + G C C F G NC+ V + C S P
Sbjct: 766 CQNGGTCDNLVNGYRCTCKKGFKGYNCQ--VNIDECASNP 803
Score = 32.3 bits (72), Expect = 0.25
Identities = 25/79 (31%), Positives = 34/79 (43%), Gaps = 13/79 (16%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C NGG+CM G C C P F G C+ D+ + C S P K C +
Sbjct: 920 CQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMNE--CLSEP-----CKNGGTCSDYVNSYT 972
Query: 140 CFPQAFLPGCDGLVMDEHL 158
C QA G DG+ + ++
Sbjct: 973 CKCQA---GFDGVHCENNI 988
Score = 32.0 bits (71), Expect = 0.32
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 5/40 (12%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C +G TC +G + C C P + G NCE++V + C + P
Sbjct: 1158 CQHGATCSDFIGGYRCECVPGYQGVNCEYEV--DECQNQP 1195
Score = 31.6 bits (70), Expect = 0.42
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 83 CLNGGTCMLGSF---CACPPSFYGRNCEHDV 110
C NGG C+ G C CPP + G+ C DV
Sbjct: 269 CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDV 299
Score = 31.2 bits (69), Expect = 0.55
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 11/63 (17%)
Query: 83 CLNGGTCML----GSFCACPPSFYGRNCEH-----DVRKENCGSVPHDTWLPKKCSLCKC 133
C+N G C+ +C CP F G C+H R +N G+ L K + C+C
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGK--ATCRC 92
Query: 134 WHG 136
G
Sbjct: 93 ASG 95
Score = 30.0 bits (66), Expect = 1.2
Identities = 16/40 (40%), Positives = 22/40 (55%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRKENCGSVP 119
C N TC+ +G F C C P F G +CE ++ + C S P
Sbjct: 465 CQNDATCLDKIGGFTCLCMPGFKGVHCELEINE--CQSNP 502
Score = 29.6 bits (65), Expect = 1.6
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 4/29 (13%)
Query: 83 CLNGGTCMLGS----FCACPPSFYGRNCE 107
CLNGGTC + S C C F G+ C+
Sbjct: 115 CLNGGTCHMLSRDTYECTCQVGFTGKECQ 143
Score = 29.6 bits (65), Expect = 1.6
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 5/40 (12%)
Query: 83 CLNGGTCM---LGSFCACPPSFYGRNCEHDVRKENCGSVP 119
CLN G C+ G C C P G NCE + ++C S P
Sbjct: 616 CLNDGRCIDLVNGYQCNCQPGTSGVNCE--INFDDCASNP 653
Score = 28.9 bits (63), Expect = 2.7
Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 3/33 (9%)
Query: 83 CLNGGTCM--LGSF-CACPPSFYGRNCEHDVRK 112
C NGGTC + S+ C C F G +CE+++ +
Sbjct: 958 CKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
Score = 28.5 bits (62), Expect = 3.6
Identities = 14/33 (42%), Positives = 17/33 (51%), Gaps = 3/33 (9%)
Query: 83 CLNGGTC--MLGSF-CACPPSFYGRNCEHDVRK 112
C NG TC + F C C F G+ CE DV +
Sbjct: 153 CANGSTCTTVANQFSCKCLTGFTGQKCETDVNE 185
Score = 27.7 bits (60), Expect = 6.1
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Query: 78 LNRTCCLNGGTCML---GSFCACPPSFYGRNCEHDVRKENC---GSVPHDTWLPKKCSL- 130
L C NGGTC G C C + G +C ++ ++C P T + + S
Sbjct: 304 LQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI--DDCAFASCTPGSTCIDRVASFS 361
Query: 131 CKCWHGQ 137
C C G+
Sbjct: 362 CMCPEGK 368
Score = 27.3 bits (59), Expect = 7.9
Identities = 14/36 (38%), Positives = 17/36 (47%), Gaps = 5/36 (13%)
Query: 87 GTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVP 119
G CM G C C P F G+ C D+ + C S P
Sbjct: 657 GICMDGINRYSCVCSPGFTGQRCNIDI--DECASNP 690
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 38.1 bits (87), Expect = 0.004
Identities = 20/41 (48%), Positives = 24/41 (58%), Gaps = 6/41 (14%)
Query: 71 GIQHSKELNRTCCLNGGTCML-----GSFCACPPSFYGRNC 106
G +H+ L+ C LNGGTC L + CACPP F GR C
Sbjct: 239 GTRHTACLSSPC-LNGGTCHLIVATGTTVCACPPGFAGRLC 278
Score = 30.0 bits (66), Expect = 1.2
Identities = 12/29 (41%), Positives = 17/29 (58%), Gaps = 5/29 (17%)
Query: 83 CLNGGTCM-----LGSFCACPPSFYGRNC 106
CLNGG+C C+CP +F G++C
Sbjct: 169 CLNGGSCSNTQDPQSYHCSCPRAFTGKDC 197
>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
Length = 618
Score = 37.7 bits (86), Expect = 0.006
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 21/62 (33%)
Query: 83 CLNGGTCMLGS------FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
C NGG C+ G+ C CPP F G NCE V +CSL C +G
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV---------------DRCSLQPCRNG 365
Query: 137 QL 138
L
Sbjct: 366 GL 367
Score = 34.3 bits (77), Expect = 0.065
Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP 119
C +GG C G CAC P + G CE V + ++P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALP 477
Score = 32.3 bits (72), Expect = 0.25
Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 28/101 (27%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C NGGTC+ G C+C F GR+C R + C + P C HG R
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRE--RADPCAARP-------------CAHGG-R 443
Query: 140 CFPQ------AFLPGCDGLVMDEHL---VASRTPELPPSAR 171
C+ A PG G + + AS P PP R
Sbjct: 444 CYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLR 484
Score = 31.2 bits (69), Expect = 0.55
Identities = 15/28 (53%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 83 CLNGGTCMLG--SF-CACPPSFYGRNCE 107
C NGG+C SF C CP FYG CE
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCE 310
Score = 30.8 bits (68), Expect = 0.72
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 83 CLNGGTCM-LGSF--CACPPSFYGRNCEHDV 110
C NGG C+ LG C C F G CEHD+
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
>gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]
Length = 587
Score = 37.7 bits (86), Expect = 0.006
Identities = 22/62 (35%), Positives = 26/62 (41%), Gaps = 21/62 (33%)
Query: 83 CLNGGTCMLGS------FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHG 136
C NGG C+ G+ C CPP F G NCE V +CSL C +G
Sbjct: 321 CFNGGLCVGGADPDSAYICHCPPGFQGSNCEKRV---------------DRCSLQPCRNG 365
Query: 137 QL 138
L
Sbjct: 366 GL 367
Score = 34.3 bits (77), Expect = 0.065
Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Query: 83 CLNGGTCML---GSFCACPPSFYGRNCEHDVRKENCGSVP 119
C +GG C G CAC P + G CE V + ++P
Sbjct: 438 CAHGGRCYAHFSGLVCACAPGYMGARCEFPVHPDGASALP 477
Score = 32.3 bits (72), Expect = 0.25
Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 28/101 (27%)
Query: 83 CLNGGTCMLGS---FCACPPSFYGRNCEHDVRKENCGSVPHDTWLPKKCSLCKCWHGQLR 139
C NGGTC+ G C+C F GR+C R + C + P C HG R
Sbjct: 400 CANGGTCVEGGGAHRCSCALGFGGRDCRE--RADPCAARP-------------CAHGG-R 443
Query: 140 CFPQ------AFLPGCDGLVMDEHL---VASRTPELPPSAR 171
C+ A PG G + + AS P PP R
Sbjct: 444 CYAHFSGLVCACAPGYMGARCEFPVHPDGASALPAAPPGLR 484
Score = 31.2 bits (69), Expect = 0.55
Identities = 15/28 (53%), Positives = 16/28 (57%), Gaps = 3/28 (10%)
Query: 83 CLNGGTCMLG--SF-CACPPSFYGRNCE 107
C NGG+C SF C CP FYG CE
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCE 310
Score = 30.8 bits (68), Expect = 0.72
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 3/31 (9%)
Query: 83 CLNGGTCM-LGSF--CACPPSFYGRNCEHDV 110
C NGG C+ LG C C F G CEHD+
Sbjct: 362 CRNGGLCLDLGHALRCRCRAGFAGPRCEHDL 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.139 0.481
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,688,007
Number of Sequences: 37866
Number of extensions: 421673
Number of successful extensions: 2000
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 85
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 1271
Number of HSP's gapped (non-prelim): 730
length of query: 188
length of database: 18,247,518
effective HSP length: 96
effective length of query: 92
effective length of database: 14,612,382
effective search space: 1344339144
effective search space used: 1344339144
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.