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Search of human proteins with 4507321
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo
sapiens]
(412 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens] 870 0.0
gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens] 435 e-122
gi|224465233 euchromatic histone-lysine N-methyltransferase 1 is... 155 6e-38
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 153 2e-37
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 153 2e-37
gi|194306650 SET domain and mariner transposase fusion [Homo sap... 139 4e-33
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 101 1e-21
gi|197313748 SET domain containing 2 [Homo sapiens] 99 7e-21
gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens] 99 9e-21
gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens] 99 9e-21
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 98 1e-20
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 98 1e-20
gi|13699811 WHSC1L1 protein isoform long [Homo sapiens] 94 2e-19
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 94 3e-19
gi|27477095 nuclear receptor binding SET domain protein 1 isofor... 91 2e-18
gi|19923586 nuclear receptor binding SET domain protein 1 isofor... 91 2e-18
gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-18
gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-18
gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform... 89 9e-18
gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isofor... 89 9e-18
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 82 7e-16
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 77 3e-14
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 76 6e-14
gi|210032580 SET domain containing 1B [Homo sapiens] 74 2e-13
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 74 3e-13
gi|55741677 SET domain containing 1A [Homo sapiens] 73 5e-13
gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens] 72 7e-13
gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens] 72 7e-13
gi|45356743 SET domain-containing 8 [Homo sapiens] 67 2e-11
gi|188035910 heterochromatin protein 1-alpha [Homo sapiens] 51 2e-06
>gi|4507321 suppressor of variegation 3-9 homolog 1 [Homo sapiens]
Length = 412
Score = 870 bits (2247), Expect = 0.0
Identities = 412/412 (100%), Positives = 412/412 (100%)
Query: 1 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY 60
MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY
Sbjct: 1 MAENLKGCSVCCKSSWNQLQDLCRLAKLSCPALGISKRNLYDFEVEYLCDYKKIREQEYY 60
Query: 61 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ 120
LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ
Sbjct: 61 LVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLRRHHRSKTPRHLDPSLANYLVQ 120
Query: 121 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG 180
KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG
Sbjct: 121 KAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGITLNQVAVG 180
Query: 181 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG 240
CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG
Sbjct: 181 CECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYDCPNRVVQKG 240
Query: 241 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD 300
IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD
Sbjct: 241 IRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFD 300
Query: 301 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE 360
LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE
Sbjct: 301 LDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEE 360
Query: 361 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF 412
LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF
Sbjct: 361 LTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYLF 412
>gi|13375930 suppressor of variegation 3-9 homolog 2 [Homo sapiens]
Length = 350
Score = 435 bits (1118), Expect = e-122
Identities = 215/360 (59%), Positives = 261/360 (72%), Gaps = 18/360 (5%)
Query: 58 EYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLERELLR-RHHRSKTPRH----LDP 112
EYYLVKW+G+PDS +TWEP QNLKC +L+QF D L + + ++ TP+ L P
Sbjct: 2 EYYLVKWKGWPDSTNTWEPLQNLKCPLLLQQFSNDKHNYLSQVKKGKAITPKDNNKTLKP 61
Query: 113 SLANYLVQKAKQRRALRRWEQELNAKRSHLGRITVENEVDLDGPPRAFVYINEYRVGEGI 172
++A Y+V+KAKQR AL+RW+ ELN +++H G I VEN VDL+GPP F YINEY+ GI
Sbjct: 62 AIAEYIVKKAKQRIALQRWQDELNRRKNHKGMIFVENTVDLEGPPSDFYYINEYKPAPGI 121
Query: 173 TL-NQVAVGCECQDCLWAPTGGCCPGASLHKFAYNDQGQVRLRAGLPIYECNSRCRCGYD 231
+L N+ GC C DC + CCP + AYN Q+++ G PIYECNSRC+CG D
Sbjct: 122 SLVNEATFGCSCTDCFFQK---CCPAEAGVLLAYNKNQQIKIPPGTPIYECNSRCQCGPD 178
Query: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
CPNR+VQKG +Y LCIFRT +GRGWGV+TL KI++ SFVMEYVGE+ITSEEAERRGQ YD
Sbjct: 179 CPNRIVQKGTQYSLCIFRTSNGRGWGVKTLVKIKRMSFVMEYVGEVITSEEAERRGQFYD 238
Query: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
+G TYLFDLDY D +TVDAA YGN+SHFVNHSCDPNLQV+NVFIDNLD RLPRIA F+
Sbjct: 239 NKGITYLFDLDYESDEFTVDAARYGNVSHFVNHSCDPNLQVFNVFIDNLDTRLPRIALFS 298
Query: 352 TRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
TRTI AGEELTFDY M+ D+ S +D + KKRVR CKCG +CR YL
Sbjct: 299 TRTINAGEELTFDYQMK-GSGDISSDSIDHS--------PAKKRVRTVCKCGAVTCRGYL 349
>gi|224465233 euchromatic histone-lysine N-methyltransferase 1 isoform
1 [Homo sapiens]
Length = 1298
Score = 155 bits (392), Expect = 6e-38
Identities = 97/269 (36%), Positives = 140/269 (52%), Gaps = 40/269 (14%)
Query: 149 NEVDLDGPPRAFVYINEYRVGEGITLNQVAVG---CEC-QDCLWAPTGGCCPGASLHKFA 204
N VD + P + Y+++ V + +++ C C DC + C G +
Sbjct: 1027 NAVDSEPCPSNYKYVSQNCVTSPMNIDRNITHLQYCVCIDDC---SSSNCMCGQLSMRCW 1083
Query: 205 YNDQGQVRLRAGLP----IYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRT 260
Y+ G++ + I+ECN C C +C NRVVQ G+R L ++RT D GWGVR+
Sbjct: 1084 YDKDGRLLPEFNMAEPPLIFECNHACSCWRNCRNRVVQNGLRARLQLYRTRD-MGWGVRS 1142
Query: 261 LEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVE-DVYTVDAAYYGNIS 319
L+ I +FV EYVGE+I+ EA+ R + +YLFDLD + +VY +DA +YGN+S
Sbjct: 1143 LQDIPPGTFVCEYVGELISDSEADVREE------DSYLFDLDNKDGEVYCIDARFYGNVS 1196
Query: 320 HFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRM 379
F+NH C+PNL VF+ + D R PRIAFF+TR I AGE+L FDY + +
Sbjct: 1197 RFINHHCEPNLVPVRVFMAHQDLRFPRIAFFSTRLIEAGEQLGFDYGERFWDI------- 1249
Query: 380 DSNFGLAGLPGSPKKRVRIECKCGTESCR 408
K C+CG+ CR
Sbjct: 1250 --------------KGKLFSCRCGSPKCR 1264
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2 isoform
b [Homo sapiens]
Length = 1176
Score = 153 bits (387), Expect = 2e-37
Identities = 102/273 (37%), Positives = 141/273 (51%), Gaps = 48/273 (17%)
Query: 149 NEVDLDGPPRAFVYINE------YRVGEGITLNQVAVGCEC-QDCLWAPTGGCCPGASLH 201
N VD + P + YI+E + IT Q C C DC + C G
Sbjct: 905 NGVDGEPCPEDYKYISENCETSTMNIDRNITHLQ---HCTCVDDC---SSSNCLCGQLSI 958
Query: 202 KFAYNDQGQV-----RLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGW 256
+ Y+ G++ ++ L I+ECN C C +C NRVVQ GI+ L ++RT GW
Sbjct: 959 RCWYDKDGRLLQEFNKIEPPL-IFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAK-MGW 1016
Query: 257 GVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVE-DVYTVDAAYY 315
GVR L+ I + +F+ EYVGE+I+ EA+ R + +YLFDLD + +VY +DA YY
Sbjct: 1017 GVRALQTIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYY 1070
Query: 316 GNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDME 375
GNIS F+NH CDPN+ VF+ + D R PRIAFF++R IR GEEL FDY + +
Sbjct: 1071 GNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDI--- 1127
Query: 376 STRMDSNFGLAGLPGSPKKRVRIECKCGTESCR 408
K C+CG+E C+
Sbjct: 1128 ------------------KSKYFTCQCGSEKCK 1142
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2 isoform
a [Homo sapiens]
Length = 1210
Score = 153 bits (387), Expect = 2e-37
Identities = 102/273 (37%), Positives = 141/273 (51%), Gaps = 48/273 (17%)
Query: 149 NEVDLDGPPRAFVYINE------YRVGEGITLNQVAVGCEC-QDCLWAPTGGCCPGASLH 201
N VD + P + YI+E + IT Q C C DC + C G
Sbjct: 939 NGVDGEPCPEDYKYISENCETSTMNIDRNITHLQ---HCTCVDDC---SSSNCLCGQLSI 992
Query: 202 KFAYNDQGQV-----RLRAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGW 256
+ Y+ G++ ++ L I+ECN C C +C NRVVQ GI+ L ++RT GW
Sbjct: 993 RCWYDKDGRLLQEFNKIEPPL-IFECNQACSCWRNCKNRVVQSGIKVRLQLYRTAK-MGW 1050
Query: 257 GVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVE-DVYTVDAAYY 315
GVR L+ I + +F+ EYVGE+I+ EA+ R + +YLFDLD + +VY +DA YY
Sbjct: 1051 GVRALQTIPQGTFICEYVGELISDAEADVR------EDDSYLFDLDNKDGEVYCIDARYY 1104
Query: 316 GNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDME 375
GNIS F+NH CDPN+ VF+ + D R PRIAFF++R IR GEEL FDY + +
Sbjct: 1105 GNISRFINHLCDPNIIPVRVFMLHQDLRFPRIAFFSSRDIRTGEELGFDYGDRFWDI--- 1161
Query: 376 STRMDSNFGLAGLPGSPKKRVRIECKCGTESCR 408
K C+CG+E C+
Sbjct: 1162 ------------------KSKYFTCQCGSEKCK 1176
>gi|194306650 SET domain and mariner transposase fusion [Homo
sapiens]
Length = 684
Score = 139 bits (351), Expect = 4e-33
Identities = 89/270 (32%), Positives = 136/270 (50%), Gaps = 34/270 (12%)
Query: 157 PRAFVYINEYRVGEGITLNQVAVGCECQDCLWAPTGGCCPGASL---HKFAYNDQGQVRL 213
P F Y ++ VG G ++ + C+ P C PG H Y+D +R
Sbjct: 48 PAPFQYTPDHVVGPGADIDPTQITFPGCICVKTP---CLPGTCSCLRHGENYDDNSCLRD 104
Query: 214 -----RAGLPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNS 268
+ P++ECN CRC C NRVVQKG+++ +F+T +GWG+RTLE I K
Sbjct: 105 IGSGGKYAEPVFECNVLCRCSDHCRNRVVQKGLQFHFQVFKTHK-KGWGLRTLEFIPKGR 163
Query: 269 FVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYT-------VDAAYYGNISHF 321
FV EY GE++ E +RR + + + Y+ + E VY VD Y GNI F
Sbjct: 164 FVCEYAGEVLGFSEVQRRIHLQTKSDSNYIIAIR--EHVYNGQVMETFVDPTYIGNIGRF 221
Query: 322 VNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDS 381
+NHSC+PNL + V ID++ +P++A FA + I EEL++DY+ + + + +
Sbjct: 222 LNHSCEPNLLMIPVRIDSM---VPKLALFAAKDIVPEEELSYDYSGRYLNLTVSEDKERL 278
Query: 382 NFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
+ G ++R C CG +SC +L
Sbjct: 279 DHG----------KLRKPCYCGAKSCTAFL 298
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 101 bits (251), Expect = 1e-21
Identities = 56/134 (41%), Positives = 81/134 (60%), Gaps = 8/134 (5%)
Query: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
C N +Q+G++ L + D GWG E ++KN F+ EY GE+I+ +EA+RRG++YD
Sbjct: 602 CKNCSIQRGLKKHL-LLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYD 660
Query: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
+ +++LF+L+ + + VDA GN F NHS +PN V + N D RI FA
Sbjct: 661 KYMSSFLFNLN---NDFVVDATRKGNKIRFANHSVNPNCYAKVVMV-NGDH---RIGIFA 713
Query: 352 TRTIRAGEELTFDY 365
R I+AGEEL FDY
Sbjct: 714 KRAIQAGEELFFDY 727
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 99.0 bits (245), Expect = 7e-21
Identities = 61/195 (31%), Positives = 96/195 (49%), Gaps = 29/195 (14%)
Query: 217 LPIYECNSRCRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGE 276
L + EC+SRC G C NR Q+ D+ + T+ +GWG+R + + N+FV+EY GE
Sbjct: 1524 LLMIECSSRCPNGDYCSNRRFQRKQHADVEVILTEK-KGWGLRAAKDLPSNTFVLEYCGE 1582
Query: 277 IITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVF 336
++ +E + R + Y R + + + D +DA GN S F+NHSC+PN +
Sbjct: 1583 VLDHKEFKARVKEYARNKNIHYYFMALKND-EIIDATQKGNCSRFMNHSCEPNCETQKWT 1641
Query: 337 IDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRV 396
++ R+ FF T+ + +G ELTFDY Q +G +
Sbjct: 1642 VNG----QLRVGFFTTKLVPSGSELTFDYQFQ-------------RYG----------KE 1674
Query: 397 RIECKCGTESCRKYL 411
+C CG+ +CR YL
Sbjct: 1675 AQKCFCGSANCRGYL 1689
>gi|224177469 SET domain, bifurcated 1 isoform 2 [Homo sapiens]
Length = 1290
Score = 98.6 bits (244), Expect = 9e-21
Identities = 62/181 (34%), Positives = 94/181 (51%), Gaps = 20/181 (11%)
Query: 149 NEVDLDGPPRAFVYINEYRVGEGITLN---QVAVGCECQDCLWAPTGGCCPGASLHKFAY 205
NE+D PP+ Y E G+G+ +N + VGC+C+D + C ++ A
Sbjct: 695 NEIDTTPPPQV-AYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATAC 753
Query: 206 NDQGQV---------RLRAGLP--IYECNSRCRCGYD-CPNRVVQKGIRYDLCIFRTDDG 253
GQ+ RL LP +YECN RC+C + C NR+VQ G++ L +F+T +
Sbjct: 754 TPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQN- 812
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAA 313
+GWG+R L+ I K SFV Y G+I+T + A++ G G Y +LD++E V
Sbjct: 813 KGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGL---EMGDEYFANLDHIESVENFKEG 869
Query: 314 Y 314
Y
Sbjct: 870 Y 870
Score = 79.0 bits (193), Expect = 7e-15
Identities = 46/120 (38%), Positives = 66/120 (55%), Gaps = 12/120 (10%)
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAA 313
RG+ +++ I S M V + ++ + Q YD + E Y +DA
Sbjct: 1165 RGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGE-----------ESCYIIDAK 1213
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
GN+ ++NHSC PNL V NVF+D D R P +AFFA++ IRAG ELT+DYN +V V+
Sbjct: 1214 LEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASK-IRAGTELTWDYNYEVGSVE 1272
>gi|224177467 SET domain, bifurcated 1 isoform 1 [Homo sapiens]
Length = 1291
Score = 98.6 bits (244), Expect = 9e-21
Identities = 62/181 (34%), Positives = 94/181 (51%), Gaps = 20/181 (11%)
Query: 149 NEVDLDGPPRAFVYINEYRVGEGITLN---QVAVGCECQDCLWAPTGGCCPGASLHKFAY 205
NE+D PP+ Y E G+G+ +N + VGC+C+D + C ++ A
Sbjct: 695 NEIDTTPPPQV-AYSKERIPGKGVFINTGPEFLVGCDCKDGCRDKSKCACHQLTIQATAC 753
Query: 206 NDQGQV---------RLRAGLP--IYECNSRCRCGYD-CPNRVVQKGIRYDLCIFRTDDG 253
GQ+ RL LP +YECN RC+C + C NR+VQ G++ L +F+T +
Sbjct: 754 TPGGQINPNSGYQYKRLEECLPTGVYECNKRCKCDPNMCTNRLVQHGLQVRLQLFKTQN- 812
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAA 313
+GWG+R L+ I K SFV Y G+I+T + A++ G G Y +LD++E V
Sbjct: 813 KGWGIRCLDDIAKGSFVCIYAGKILTDDFADKEGL---EMGDEYFANLDHIESVENFKEG 869
Query: 314 Y 314
Y
Sbjct: 870 Y 870
Score = 83.2 bits (204), Expect = 4e-16
Identities = 46/120 (38%), Positives = 66/120 (55%), Gaps = 11/120 (9%)
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAA 313
RG+ +++ I S M V + ++ + Q YD + E Y +DA
Sbjct: 1165 RGFALKSTHGIAIKSTNMASVDKGESAPVRKNTRQFYDGE-----------ESCYIIDAK 1213
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
GN+ ++NHSC PNL V NVF+D D R P +AFFA++ IRAG ELT+DYN +V V+
Sbjct: 1214 LEGNLGRYLNHSCSPNLFVQNVFVDTHDLRFPWVAFFASKRIRAGTELTWDYNYEVGSVE 1273
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/134 (41%), Positives = 79/134 (58%), Gaps = 8/134 (5%)
Query: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
C N +Q+G + L + D GWG+ + ++KN F+ EY GEII+ +EA+RRG++YD
Sbjct: 562 CKNCSIQRGSKKHL-LLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD 620
Query: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
+ ++LF+L+ + + VDA GN F NHS +PN V + N D RI FA
Sbjct: 621 KYMCSFLFNLN---NDFVVDATRKGNKIRFANHSVNPNCYA-KVMMVNGDH---RIGIFA 673
Query: 352 TRTIRAGEELTFDY 365
R I+ GEEL FDY
Sbjct: 674 KRAIQTGEELFFDY 687
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 98.2 bits (243), Expect = 1e-20
Identities = 55/134 (41%), Positives = 79/134 (58%), Gaps = 8/134 (5%)
Query: 232 CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYD 291
C N +Q+G + L + D GWG+ + ++KN F+ EY GEII+ +EA+RRG++YD
Sbjct: 606 CKNCSIQRGSKKHL-LLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD 664
Query: 292 RQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFA 351
+ ++LF+L+ + + VDA GN F NHS +PN V + N D RI FA
Sbjct: 665 KYMCSFLFNLN---NDFVVDATRKGNKIRFANHSVNPNCYA-KVMMVNGDH---RIGIFA 717
Query: 352 TRTIRAGEELTFDY 365
R I+ GEEL FDY
Sbjct: 718 KRAIQTGEELFFDY 731
>gi|13699811 WHSC1L1 protein isoform long [Homo sapiens]
Length = 1437
Score = 94.4 bits (233), Expect = 2e-19
Identities = 64/193 (33%), Positives = 88/193 (45%), Gaps = 30/193 (15%)
Query: 220 YECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEII 278
YEC+ + C G C N+ K + D I +T+ RGWG+RT I+K FV EYVGE+I
Sbjct: 1121 YECHPQVCPAGDRCQNQCFTKRLYPDAEIIKTER-RGWGLRTKRSIKKGEFVNEYVGELI 1179
Query: 279 TSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFID 338
EE R + T + L +D +DA GN S F+NHSC+PN + ++
Sbjct: 1180 DEEECRLRIKRAHENSVTNFYMLTVTKD-RIIDAGPKGNYSRFMNHSCNPNCETQKWTVN 1238
Query: 339 NLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRI 398
R+ FA I AG ELTF+YN+ R
Sbjct: 1239 G----DVRVGLFALCDIPAGMELTFNYNLDC-----------------------LGNGRT 1271
Query: 399 ECKCGTESCRKYL 411
EC CG ++C +L
Sbjct: 1272 ECHCGADNCSGFL 1284
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 93.6 bits (231), Expect = 3e-19
Identities = 58/192 (30%), Positives = 95/192 (49%), Gaps = 35/192 (18%)
Query: 221 ECN-SRCRCGYDCPNRVVQKGIRYDLCI--FRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
EC+ + C CG C N+ +Q+ + C+ FR ++ +GWG+RT E ++ F++EY+GE+
Sbjct: 2116 ECSPNTCPCGEQCCNQRIQRH-EWVQCLERFRAEE-KGWGIRTKEPLKAGQFIIEYLGEV 2173
Query: 278 ITSEEAERRG-QIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVF 336
++ +E R + Y Y +LD +D+ GN + F+NHSCDPN ++
Sbjct: 2174 VSEQEFRNRMIEQYHNHSDHYCLNLD---SGMVIDSYRMGNEARFINHSCDPNCEMQKWS 2230
Query: 337 IDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRV 396
++ + RI +A + + AG ELT+DYN V+ +
Sbjct: 2231 VNG----VYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQL------------------- 2267
Query: 397 RIECKCGTESCR 408
CKCG E CR
Sbjct: 2268 ---CKCGFEKCR 2276
>gi|27477095 nuclear receptor binding SET domain protein 1 isoform a
[Homo sapiens]
Length = 2427
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/151 (37%), Positives = 78/151 (51%), Gaps = 7/151 (4%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
+YEC+ C G C N+ K ++ IFRT RGWG+RT I+K FV EYVGE+
Sbjct: 1648 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQ-RGWGLRTKTDIKKGEFVNEYVGEL 1706
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T + L +D +DA GN + F+NH C PN + +
Sbjct: 1707 IDEEECRARIRYAQEHDITNFYMLTLDKD-RIIDAGPKGNYARFMNHCCQPNCETQKWSV 1765
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQ 368
+ R+ FA I+AG ELTF+YN++
Sbjct: 1766 NG----DTRVGLFALSDIKAGTELTFNYNLE 1792
>gi|19923586 nuclear receptor binding SET domain protein 1 isoform b
[Homo sapiens]
Length = 2696
Score = 90.9 bits (224), Expect = 2e-18
Identities = 56/151 (37%), Positives = 78/151 (51%), Gaps = 7/151 (4%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
+YEC+ C G C N+ K ++ IFRT RGWG+RT I+K FV EYVGE+
Sbjct: 1917 LYECHPTVCPAGGRCQNQCFSKRQYPEVEIFRTLQ-RGWGLRTKTDIKKGEFVNEYVGEL 1975
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T + L +D +DA GN + F+NH C PN + +
Sbjct: 1976 IDEEECRARIRYAQEHDITNFYMLTLDKD-RIIDAGPKGNYARFMNHCCQPNCETQKWSV 2034
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQ 368
+ R+ FA I+AG ELTF+YN++
Sbjct: 2035 NG----DTRVGLFALSDIKAGTELTFNYNLE 2061
>gi|19913358 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
++EC+ + C G C N+ K + I +TD G+GWG+ IRK FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T+ + L +D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397
+ R+ FA I AG ELTF+YN+ D + E T
Sbjct: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
Query: 398 IECKCGTESCRKYL 411
C+CG +C +L
Sbjct: 1190 -VCRCGASNCSGFL 1202
>gi|19913350 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
++EC+ + C G C N+ K + I +TD G+GWG+ IRK FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T+ + L +D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397
+ R+ FA I AG ELTF+YN+ D + E T
Sbjct: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
Query: 398 IECKCGTESCRKYL 411
C+CG +C +L
Sbjct: 1190 -VCRCGASNCSGFL 1202
>gi|19913348 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
++EC+ + C G C N+ K + I +TD G+GWG+ IRK FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T+ + L +D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397
+ R+ FA I AG ELTF+YN+ D + E T
Sbjct: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
Query: 398 IECKCGTESCRKYL 411
C+CG +C +L
Sbjct: 1190 -VCRCGASNCSGFL 1202
>gi|109633019 Wolf-Hirschhorn syndrome candidate 1 protein isoform 1
[Homo sapiens]
Length = 1365
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/194 (32%), Positives = 89/194 (45%), Gaps = 30/194 (15%)
Query: 219 IYECNSR-CRCGYDCPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEI 277
++EC+ + C G C N+ K + I +TD G+GWG+ IRK FV EYVGE+
Sbjct: 1038 MFECHPQVCPAGEFCQNQCFTKRQYPETKIIKTD-GKGWGLVAKRDIRKGEFVNEYVGEL 1096
Query: 278 ITSEEAERRGQIYDRQGATYLFDLDYVEDVYTVDAAYYGNISHFVNHSCDPNLQVYNVFI 337
I EE R + T+ + L +D +DA GN S F+NHSC PN + +
Sbjct: 1097 IDEEECMARIKHAHENDITHFYMLTIDKD-RIIDAGPKGNYSRFMNHSCQPNCETLKWTV 1155
Query: 338 DNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVDMESTRMDSNFGLAGLPGSPKKRVR 397
+ R+ FA I AG ELTF+YN+ D + E T
Sbjct: 1156 NG----DTRVGLFAVCDIPAGTELTFNYNL--DCLGNEKT-------------------- 1189
Query: 398 IECKCGTESCRKYL 411
C+CG +C +L
Sbjct: 1190 -VCRCGASNCSGFL 1202
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 82.4 bits (202), Expect = 7e-16
Identities = 52/158 (32%), Positives = 74/158 (46%), Gaps = 30/158 (18%)
Query: 255 GWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG-ATYLFDLDYVEDVYTVDAA 313
G G+ I V+EY G +I S + ++R + YD +G Y+F +D D VDA
Sbjct: 3840 GRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRID---DSEVVDAT 3896
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
+GN + F+NHSC+PN + ID I FA R I GEELT+DY ++
Sbjct: 3897 MHGNAARFINHSCEPNCYSRVINIDG----QKHIVIFAMRKIYRGEELTYDYKFPIEDA- 3951
Query: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
SN ++ C CG + CRK+L
Sbjct: 3952 -------SN--------------KLPCNCGAKKCRKFL 3968
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 77.0 bits (188), Expect = 3e-14
Identities = 49/159 (30%), Positives = 77/159 (48%), Gaps = 30/159 (18%)
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG-ATYLFDLDYVEDVYTVDA 312
+G G+ + + K++ V+EY+G II +E A RR +IY+ Q Y+F + + + +DA
Sbjct: 5407 QGLGLYAAKDLEKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMF---RINNEHVIDA 5463
Query: 313 AYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPV 372
G + ++NHSC PN V D D +I ++R I GEELT+DY
Sbjct: 5464 TLTGGPARYINHSCAPNCVAEVVTFDKED----KIIIISSRRIPKGEELTYDYQF----- 5514
Query: 373 DMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
D E + +I C CG +CRK++
Sbjct: 5515 DFEDDQH-----------------KIPCHCGAWNCRKWM 5536
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 75.9 bits (185), Expect = 6e-14
Identities = 50/158 (31%), Positives = 73/158 (46%), Gaps = 30/158 (18%)
Query: 255 GWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG-ATYLFDLDYVEDVYTVDAA 313
G G+ I V+EY G +I S ++R + YD +G Y+F +D D VDA
Sbjct: 2586 GRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMD---DFDVVDAT 2642
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
+GN + F+NHSC+PN + + E I FA R I GEELT+DY ++
Sbjct: 2643 MHGNAARFINHSCEPNCFSRVIHV----EGQKHIVIFALRRILRGEELTYDYKFPIEDA- 2697
Query: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
SN ++ C CG + CR++L
Sbjct: 2698 -------SN--------------KLPCNCGAKRCRRFL 2714
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 74.3 bits (181), Expect = 2e-13
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 33/155 (21%)
Query: 256 WGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG--ATYLFDLDYVEDVYTVDAA 313
WG+ +E I + V+EYVG+ I A+ R + Y+ +G ++Y+F +D+ +DA
Sbjct: 1796 WGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEGIGSSYMFRVDHDT---IIDAT 1852
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
GN + F+NHSC+PN + + E +I ++ + I EE+T+DY
Sbjct: 1853 KCGNFARFINHSCNPNCYAKVITV----ESQKKIVIYSKQHINVNEEITYDYKF------ 1902
Query: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCR 408
P + V+I C CG+E+CR
Sbjct: 1903 ------------------PIEDVKIPCLCGSENCR 1919
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 73.6 bits (179), Expect = 3e-13
Identities = 48/159 (30%), Positives = 77/159 (48%), Gaps = 30/159 (18%)
Query: 254 RGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQG-ATYLFDLDYVEDVYTVDA 312
+G G+ I K++ V+EY+G II +E A R+ ++Y+ Q Y+F +D + + +DA
Sbjct: 4781 QGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMD---NDHVIDA 4837
Query: 313 AYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPV 372
G + ++NHSC PN V ER +I ++R I+ GEEL +DY
Sbjct: 4838 TLTGGPARYINHSCAPNCVAEVVTF----ERGHKIIISSSRRIQKGEELCYDYKF----- 4888
Query: 373 DMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRKYL 411
D E + +I C CG +CRK++
Sbjct: 4889 DFEDDQH-----------------KIPCHCGAVNCRKWM 4910
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 72.8 bits (177), Expect = 5e-13
Identities = 47/155 (30%), Positives = 73/155 (47%), Gaps = 33/155 (21%)
Query: 256 WGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQ--GATYLFDLDYVEDVYTVDAA 313
WG+ +E I + V+EYVG+ I A+ R + Y ++ G++YLF +D+ +DA
Sbjct: 1580 WGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFRVDHDT---IIDAT 1636
Query: 314 YYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDYNMQVDPVD 373
GN++ F+NH C PN + I E +I ++ + I EE+T+DY
Sbjct: 1637 KCGNLARFINHCCTPNCYAKVITI----ESQKKIVIYSKQPIGVDEEITYDYKF------ 1686
Query: 374 MESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCR 408
P + +I C CGTESCR
Sbjct: 1687 ------------------PLEDNKIPCLCGTESCR 1703
>gi|238624099 SET domain, bifurcated 2 isoform b [Homo sapiens]
Length = 707
Score = 72.4 bits (176), Expect = 7e-13
Identities = 38/104 (36%), Positives = 53/104 (50%), Gaps = 21/104 (20%)
Query: 306 DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDY 365
+V+ +DA GN+ F+NHSC PNL V NVF++ + P +AFF R ++A ELT+DY
Sbjct: 622 NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDY 681
Query: 366 NMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK 409
+ V P+K I C+CG CRK
Sbjct: 682 GYEAGTV-------------------PEK--EIFCQCGVNKCRK 704
Score = 58.5 bits (140), Expect = 1e-08
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 4/77 (5%)
Query: 212 RLRAGLP--IYECNSRCRCGYD-CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNS 268
RL+ +P IYEC+ C+C C NRVVQ G + L +F+T+ +GWGVR L+ I + +
Sbjct: 321 RLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDIDRGT 379
Query: 269 FVMEYVGEIITSEEAER 285
FV Y G +++ E+
Sbjct: 380 FVCIYSGRLLSRANTEK 396
>gi|238624095 SET domain, bifurcated 2 isoform a [Homo sapiens]
Length = 719
Score = 72.4 bits (176), Expect = 7e-13
Identities = 38/104 (36%), Positives = 53/104 (50%), Gaps = 21/104 (20%)
Query: 306 DVYTVDAAYYGNISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRTIRAGEELTFDY 365
+V+ +DA GN+ F+NHSC PNL V NVF++ + P +AFF R ++A ELT+DY
Sbjct: 634 NVFLLDATKEGNVGRFLNHSCCPNLLVQNVFVETHNRNFPLVAFFTNRYVKARTELTWDY 693
Query: 366 NMQVDPVDMESTRMDSNFGLAGLPGSPKKRVRIECKCGTESCRK 409
+ V P+K I C+CG CRK
Sbjct: 694 GYEAGTV-------------------PEK--EIFCQCGVNKCRK 716
Score = 58.5 bits (140), Expect = 1e-08
Identities = 31/77 (40%), Positives = 47/77 (61%), Gaps = 4/77 (5%)
Query: 212 RLRAGLP--IYECNSRCRCGYD-CPNRVVQKGIRYDLCIFRTDDGRGWGVRTLEKIRKNS 268
RL+ +P IYEC+ C+C C NRVVQ G + L +F+T+ +GWGVR L+ I + +
Sbjct: 333 RLQRQIPTGIYECSLLCKCNRQLCQNRVVQHGPQVRLQVFKTEQ-KGWGVRCLDDIDRGT 391
Query: 269 FVMEYVGEIITSEEAER 285
FV Y G +++ E+
Sbjct: 392 FVCIYSGRLLSRANTEK 408
>gi|45356743 SET domain-containing 8 [Homo sapiens]
Length = 352
Score = 67.4 bits (163), Expect = 2e-11
Identities = 43/131 (32%), Positives = 69/131 (52%), Gaps = 12/131 (9%)
Query: 238 QKGIRYDLCIFRTDDGRGWGVRTLEKIRKNSFVMEYVGEIITSEEAERRGQIYDRQGAT- 296
++G++ DL DG+G GV ++ + FV+EY G++I +A++R +Y + +T
Sbjct: 215 EEGMKIDLI-----DGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTG 269
Query: 297 -YLFDLDYVEDVYTVDAAYYGN-ISHFVNHSCDPNLQVYNVFIDNLDERLPRIAFFATRT 354
Y++ Y+ Y VDA N + +NHS N Q ID +P + A+R
Sbjct: 270 CYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG----VPHLILIASRD 325
Query: 355 IRAGEELTFDY 365
I AGEEL +DY
Sbjct: 326 IAAGEELLYDY 336
>gi|188035910 heterochromatin protein 1-alpha [Homo sapiens]
Length = 191
Score = 50.8 bits (120), Expect = 2e-06
Identities = 18/54 (33%), Positives = 35/54 (64%)
Query: 42 DFEVEYLCDYKKIREQEYYLVKWRGYPDSESTWEPRQNLKCVRILKQFHKDLER 95
++ VE + D + ++ Q YL+KW+G+ + +TWEP +NL C ++ +F K ++
Sbjct: 19 EYVVEKVLDRRVVKGQVEYLLKWKGFSEEHNTWEPEKNLDCPELISEFMKKYKK 72
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,011,266
Number of Sequences: 37866
Number of extensions: 785824
Number of successful extensions: 1907
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 64
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1739
Number of HSP's gapped (non-prelim): 110
length of query: 412
length of database: 18,247,518
effective HSP length: 105
effective length of query: 307
effective length of database: 14,271,588
effective search space: 4381377516
effective search space used: 4381377516
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.