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Search of human proteins with 4506939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506939 sonic hedgehog preproprotein [Homo sapiens]
(462 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506939 sonic hedgehog preproprotein [Homo sapiens] 931 0.0
gi|119392086 Indian hedgehog homolog [Homo sapiens] 478 e-135
gi|19482158 desert hedgehog preproprotein [Homo sapiens] 442 e-124
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 37 0.038
gi|122937319 even-skipped homeobox 2 [Homo sapiens] 37 0.049
gi|197333809 joined to JAZF1 [Homo sapiens] 35 0.11
gi|239755981 PREDICTED: hypothetical protein XP_002344766 [Homo ... 35 0.19
gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo ... 35 0.19
gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo ... 35 0.19
gi|55741655 anoctamin 8 [Homo sapiens] 34 0.24
gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens] 34 0.32
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 34 0.32
gi|223671856 coiled-coil domain containing 85C [Homo sapiens] 33 0.42
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 33 0.55
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 33 0.55
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 33 0.55
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 33 0.55
gi|31657109 zinc finger protein 282 [Homo sapiens] 33 0.55
gi|238859557 regulatory factor X1 [Homo sapiens] 33 0.71
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens] 33 0.71
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens] 33 0.71
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens] 33 0.71
gi|150170699 kinesin family member 26A [Homo sapiens] 33 0.71
gi|61835232 growth differentiation factor 7 preproprotein [Homo ... 33 0.71
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 32 0.93
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 32 0.93
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 32 0.93
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 32 0.93
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 32 0.93
gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens] 32 0.93
>gi|4506939 sonic hedgehog preproprotein [Homo sapiens]
Length = 462
Score = 931 bits (2407), Expect = 0.0
Identities = 462/462 (100%), Positives = 462/462 (100%)
Query: 1 MLLLARCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASG 60
MLLLARCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASG
Sbjct: 1 MLLLARCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASG 60
Query: 61 RYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGV 120
RYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGV
Sbjct: 61 RYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGV 120
Query: 121 KLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAH 180
KLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAH
Sbjct: 121 KLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAH 180
Query: 181 IHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLT 240
IHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLT
Sbjct: 181 IHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLT 240
Query: 241 FLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALG 300
FLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALG
Sbjct: 241 FLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALG 300
Query: 301 PRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVL 360
PRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVL
Sbjct: 301 PRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVL 360
Query: 361 ASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGA 420
ASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGA
Sbjct: 361 ASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGA 420
Query: 421 ADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS 462
ADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
Sbjct: 421 ADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS 462
>gi|119392086 Indian hedgehog homolog [Homo sapiens]
Length = 411
Score = 478 bits (1231), Expect = e-135
Identities = 262/453 (57%), Positives = 307/453 (67%), Gaps = 59/453 (13%)
Query: 7 CLLLVLVSSLLVCSGLACGPGRGFGKRRHP-KKLTPLAYKQFIPNVAEKTLGASGRYEGK 65
CL+L+L+ L+V + CGPGR G RR P +KL PLAYKQF PNV EKTLGASGRYEGK
Sbjct: 13 CLVLLLL--LVVPAAWGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPEKTLGASGRYEGK 70
Query: 66 ISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVT 125
I+R+SERFKELTPNYNPDIIFKDEENTGADRLMTQRCKD+LN+LAISVMNQWPGVKLRVT
Sbjct: 71 IARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISVMNQWPGVKLRVT 130
Query: 126 EGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSV 185
EGWDEDGHHSEESLHYEGRAVDITTSDRDR+KYG+LARLAVEAGFDWVYYESKAH+HCSV
Sbjct: 131 EGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWVYYESKAHVHCSV 190
Query: 186 KAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLTFLDRD 245
K+E+S AAK+GGCFP A V LE G + + PGDRVLA + G +SD L FLDR+
Sbjct: 191 KSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSPTFSDVLIFLDRE 250
Query: 246 DGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALGPRALF 305
+ F VIET++P RL LT AHLLF A ++ EP A RA F
Sbjct: 251 PHRLRAFQVIETQDPPRRLALTPAHLLFTADNHT----EPAARF------------RATF 294
Query: 306 ASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVLASCYA 365
AS V+PGQ V V G L PA V +V+ + A GAYAPLT GT+++ V+ASC+A
Sbjct: 295 ASHVQPGQYVLVA----GVPGLQPARVAAVS-THVALGAYAPLTKHGTLVVEDVVASCFA 349
Query: 366 VIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPG 425
+ +H A AF P RL H+L + PG
Sbjct: 350 AVADHHLAQLAFWPLRLFHSL-------------------------------AWGSWTPG 378
Query: 426 AGATAGIHWYSQLLYQIGTWLLDSEALHPLGMA 458
G+HWY QLLY++G LL+ + HPLGM+
Sbjct: 379 ----EGVHWYPQLLYRLGRLLLEEGSFHPLGMS 407
>gi|19482158 desert hedgehog preproprotein [Homo sapiens]
Length = 396
Score = 442 bits (1138), Expect = e-124
Identities = 245/450 (54%), Positives = 299/450 (66%), Gaps = 58/450 (12%)
Query: 1 MLLLARCLLLVLVSSLLVCSGLACGPGRG-FGKRRHPKK-LTPLAYKQFIPNVAEKTLGA 58
M LL L L ++ LL +CGPGRG G+RR+ +K L PL YKQF+P V E+TLGA
Sbjct: 1 MALLTNLLPLCCLA-LLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGA 59
Query: 59 SGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWP 118
SG EG+++R SERF++L PNYNPDIIFKDEEN+GADRLMT+RCK+++NALAI+VMN WP
Sbjct: 60 SGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWP 119
Query: 119 GVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESK 178
GV+LRVTEGWDEDGHH+++SLHYEGRA+DITTSDRDR+KYG+LARLAVEAGFDWVYYES+
Sbjct: 120 GVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESR 179
Query: 179 AHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDF 238
H+H SVKA+NS+A ++GGCFPG+ATV L G K +++L GD VLAAD GR++ +
Sbjct: 180 NHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPV 239
Query: 239 LTFLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGP-PSGG 297
L FLDRD + F +ET P +LLLT HL+F A GP P+ G
Sbjct: 240 LLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAA---------------RGPAPAPG 284
Query: 298 ALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILIN 357
P +FA R+R G V G L PA V V EEA G +APLTA GT+L+N
Sbjct: 285 DFAP--VFARRLRAGDSVLA----PGGDALRPARVARVA-REEAVGVFAPLTAHGTLLVN 337
Query: 358 RVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTA 417
VLASCYAV+E H WAHRAFAP RL HAL A L
Sbjct: 338 DVLASCYAVLESHQWAHRAFAPLRLLHALGALL--------------------------- 370
Query: 418 PGAADAPGAGATAGIHWYSQLLYQIGTWLL 447
PG A P G+HWYS+LLY++ LL
Sbjct: 371 PGGAVQP-----TGMHWYSRLLYRLAEELL 395
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 37.0 bits (84), Expect = 0.038
Identities = 23/62 (37%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 373 AHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGA-TAG 431
A A P+ ++LLAA + +D G GGG GGGGG G PG+ A T+G
Sbjct: 2 ATAASNPYLPGNSLLAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSG 61
Query: 432 IH 433
+
Sbjct: 62 AY 63
>gi|122937319 even-skipped homeobox 2 [Homo sapiens]
Length = 476
Score = 36.6 bits (83), Expect = 0.049
Identities = 41/141 (29%), Positives = 52/141 (36%), Gaps = 24/141 (17%)
Query: 287 ASSGSGPPSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAY- 345
A++ + SG A + FA+ +RP ++ LL + H G Y
Sbjct: 294 AAAAAAAASGAAAAASSPFATSIRPLDTFRALSHPYSRPELLCSFRHP--------GLYQ 345
Query: 346 APLTAQGTILINRVLASCYAVIEEHSWAHRAFAP---------------FRLAHALLAAL 390
AP A G A+ A S A A AP + A A AA
Sbjct: 346 APAAAAGLNSAASAAAAAAAAAAAASSAAAAGAPPSGGSAPCSCLSCHSSQSAAAAAAAA 405
Query: 391 APARTDRGGDSGGGDRGGGGG 411
A A RGG GGG GGGGG
Sbjct: 406 AAALGSRGGGGGGGGGGGGGG 426
>gi|197333809 joined to JAZF1 [Homo sapiens]
Length = 739
Score = 35.4 bits (80), Expect = 0.11
Identities = 19/39 (48%), Positives = 22/39 (56%)
Query: 388 AALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGA 426
+A A T GG SGGG GGGG A ++ AA A GA
Sbjct: 28 SAAVAAATASGGKSGGGSCGGGGSYSASSSSSAAAAAGA 66
>gi|239755981 PREDICTED: hypothetical protein XP_002344766 [Homo
sapiens]
Length = 307
Score = 34.7 bits (78), Expect = 0.19
Identities = 48/175 (27%), Positives = 65/175 (37%), Gaps = 31/175 (17%)
Query: 276 PHNDSATGEPEA--SSGSGPPSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVH 333
P + T +P + S + +G GPR + PG R A RDG RR A H
Sbjct: 126 PARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA-RDGSRR---KAGH 181
Query: 334 SVTLSEEAAGAYAPLTAQGT--------------ILINRVLASCYAVIEEHSWAHRAFA- 378
T + A+G+ + + +L+ AV++ HS+ A
Sbjct: 182 GCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDT 241
Query: 379 --PFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
P R H R RGG GGG G GG A T G A A + A G
Sbjct: 242 PDPRRGHHR------HRRRQRGGGRGGG--GRGGREAAATVHGNAAASSSAAARG 288
>gi|239750506 PREDICTED: hypothetical protein XP_002347417 [Homo
sapiens]
Length = 325
Score = 34.7 bits (78), Expect = 0.19
Identities = 48/175 (27%), Positives = 65/175 (37%), Gaps = 31/175 (17%)
Query: 276 PHNDSATGEPEA--SSGSGPPSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVH 333
P + T +P + S + +G GPR + PG R A RDG RR A H
Sbjct: 144 PARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA-RDGSRR---KAGH 199
Query: 334 SVTLSEEAAGAYAPLTAQGT--------------ILINRVLASCYAVIEEHSWAHRAFA- 378
T + A+G+ + + +L+ AV++ HS+ A
Sbjct: 200 GCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDT 259
Query: 379 --PFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
P R H R RGG GGG G GG A T G A A + A G
Sbjct: 260 PDPRRGHHR------HRRRQRGGGRGGG--GRGGREAAATVHGNAAASSSAAARG 306
>gi|239744803 PREDICTED: hypothetical protein XP_002343287 [Homo
sapiens]
Length = 325
Score = 34.7 bits (78), Expect = 0.19
Identities = 48/175 (27%), Positives = 65/175 (37%), Gaps = 31/175 (17%)
Query: 276 PHNDSATGEPEA--SSGSGPPSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVH 333
P + T +P + S + +G GPR + PG R A RDG RR A H
Sbjct: 144 PARKTLTCQPRSIESPATASSAGCGSGPRVPQVRLLGPGGRPSSPA-RDGSRR---KAGH 199
Query: 334 SVTLSEEAAGAYAPLTAQGT--------------ILINRVLASCYAVIEEHSWAHRAFA- 378
T + A+G+ + + +L+ AV++ HS+ A
Sbjct: 200 GCTSQSQGDAVAMEAEARGSPGGRVLMQELTLLPVEASLILSVVAAVLQLHSYRRPAGDT 259
Query: 379 --PFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
P R H R RGG GGG G GG A T G A A + A G
Sbjct: 260 PDPRRGHHR------HRRRQRGGGRGGG--GRGGREAAATVHGNAAASSSAAARG 306
>gi|55741655 anoctamin 8 [Homo sapiens]
Length = 1232
Score = 34.3 bits (77), Expect = 0.24
Identities = 23/52 (44%), Positives = 26/52 (50%), Gaps = 7/52 (13%)
Query: 378 APFRLAHALLAAL-----APARTDRGGDSGGGDRGGGGGRVALTAPGAADAP 424
A + LA ALL L AP R + D GGG GGGGR L+ G AP
Sbjct: 504 AVWELARALLGLLSLRRPAPRRLEPQADEGGGGGSGGGGRRCLS--GGCGAP 553
>gi|22547197 zinc finger protein of the cerebellum 2 [Homo sapiens]
Length = 532
Score = 33.9 bits (76), Expect = 0.32
Identities = 19/45 (42%), Positives = 22/45 (48%)
Query: 383 AHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAG 427
A A AA A + RGG SG G GGG G + + G A G G
Sbjct: 462 AAAAAAAAAVSAVHRGGGSGSGGAGGGSGGGSGSGGGGGGAGGGG 506
Score = 32.0 bits (71), Expect = 1.2
Identities = 18/36 (50%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 398 GGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGIH 433
GG SGGG GGGG A G + G+G TAG H
Sbjct: 486 GGGSGGGSGSGGGGGGAGGGGGGSSGGGSG-TAGGH 520
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 33.9 bits (76), Expect = 0.32
Identities = 18/33 (54%), Positives = 18/33 (54%)
Query: 393 ARTDRGGDSGGGDRGGGGGRVALTAPGAADAPG 425
AR G GGGD GGGGG A A G A A G
Sbjct: 5 ARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAG 37
>gi|223671856 coiled-coil domain containing 85C [Homo sapiens]
Length = 419
Score = 33.5 bits (75), Expect = 0.42
Identities = 18/44 (40%), Positives = 22/44 (50%)
Query: 385 ALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGA 428
A LAA A GG G G R + +L+ P + APGAGA
Sbjct: 156 AALAATGAASGGGGGGGGAGSRSSIDSQASLSGPLSGGAPGAGA 199
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 33.1 bits (74), Expect = 0.55
Identities = 15/33 (45%), Positives = 17/33 (51%)
Query: 398 GGDSGGGDRGGGGGRVALTAPGAADAPGAGATA 430
GG GGG GGGGG + G A G GA +
Sbjct: 159 GGSGGGGHGGGGGGGSSNAGGGGGGASGGGANS 191
Score = 32.0 bits (71), Expect = 1.2
Identities = 17/36 (47%), Positives = 20/36 (55%), Gaps = 4/36 (11%)
Query: 396 DRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
D+ G SGGG GGGGG + A G G GA+ G
Sbjct: 156 DKVGGSGGGGHGGGGGGGSSNAGGG----GGGASGG 187
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 33.1 bits (74), Expect = 0.55
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 385 ALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATA 430
A A+L+ A G +GGG G GGG VA GA GAGA A
Sbjct: 331 AAAASLSVAAASGGAGTGGG--GAGGGCVAGVGVGAGAGAGAGAGA 374
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/50 (36%), Positives = 23/50 (46%)
Query: 382 LAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
+A A L+A A + + G G GGG G + G GAGA AG
Sbjct: 324 VAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAG 373
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 33.1 bits (74), Expect = 0.55
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 385 ALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATA 430
A A+L+ A G +GGG G GGG VA GA GAGA A
Sbjct: 331 AAAASLSVAAASGGAGTGGG--GAGGGCVAGVGVGAGAGAGAGAGA 374
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/50 (36%), Positives = 23/50 (46%)
Query: 382 LAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
+A A L+A A + + G G GGG G + G GAGA AG
Sbjct: 324 VAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAG 373
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 33.1 bits (74), Expect = 0.55
Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
Query: 385 ALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATA 430
A A+L+ A G +GGG G GGG VA GA GAGA A
Sbjct: 331 AAAASLSVAAASGGAGTGGG--GAGGGCVAGVGVGAGAGAGAGAGA 374
Score = 31.6 bits (70), Expect = 1.6
Identities = 18/50 (36%), Positives = 23/50 (46%)
Query: 382 LAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
+A A L+A A + + G G GGG G + G GAGA AG
Sbjct: 324 VAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAG 373
>gi|31657109 zinc finger protein 282 [Homo sapiens]
Length = 671
Score = 33.1 bits (74), Expect = 0.55
Identities = 19/41 (46%), Positives = 19/41 (46%), Gaps = 7/41 (17%)
Query: 391 APARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
AP DR GGGD GGGGG GA GAG G
Sbjct: 464 APPGGDRSTGGGGGDGGGGGG-------GAEAGTGAGGGCG 497
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 32.7 bits (73), Expect = 0.71
Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 10/117 (8%)
Query: 323 GDRRLLPAAVHSVTLSEEAAGAYAPLT------AQGTILINRVLASCYAVIEEHSWAHRA 376
GD +A+ S T S Y A GT A+ AV S
Sbjct: 301 GDASYTASAIRSSTYSYPETPLYTQTASTSYYEAAGTATQVSTPATSQAVASSGSMPMYV 360
Query: 377 FAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGIH 433
+A + + + GG SGGG GGGGG G+ G G+ AG +
Sbjct: 361 SGSQVVASSTSTGAGASNSSGGGGSGGGGGGGGGG----GGGGSGSTGGGGSGAGTY 413
>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 32.7 bits (73), Expect = 0.71
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 387 LAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADA-PGAGA 428
L L+P R D GG S GG G L AP A A P AGA
Sbjct: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGA 335
>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 32.7 bits (73), Expect = 0.71
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 387 LAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADA-PGAGA 428
L L+P R D GG S GG G L AP A A P AGA
Sbjct: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGA 335
>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
Length = 414
Score = 32.7 bits (73), Expect = 0.71
Identities = 20/43 (46%), Positives = 21/43 (48%), Gaps = 1/43 (2%)
Query: 387 LAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADA-PGAGA 428
L L+P R D GG S GG G L AP A A P AGA
Sbjct: 293 LGRLSPPRADTGGSSSGGCSGPDSKHRTLPAPPAPTAWPAAGA 335
>gi|150170699 kinesin family member 26A [Homo sapiens]
Length = 1882
Score = 32.7 bits (73), Expect = 0.71
Identities = 52/185 (28%), Positives = 69/185 (37%), Gaps = 28/185 (15%)
Query: 257 TREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALGPRALFASRVRPGQRVY 316
TRE L A+H APH + P ++ S G A GP R P
Sbjct: 136 TREAMHLLQAPASHEDLDAPHGGPSLAPPSTTTSSRDTPGPA-GPAGRQPGRAGP----- 189
Query: 317 VVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVLASCYAVIEEHSWAHRA 376
D + L + SV +S AG L+ TI + L ++V +S+
Sbjct: 190 -----DRTKGLAWSPGPSVQVSVAPAGLGGALSTV-TIQAQQCLEGMWSVSRVNSF---- 239
Query: 377 FAPFRLAHALLAALAPARTDR-----GGDSGGGDRGGGGG--RVALTAP-----GAADAP 424
P LA A +AA+A A T R G G G GG AL P G + P
Sbjct: 240 LPPACLAEAAVAAVAVADTVRECPPVAGPDGLSKAWGRGGVCTSALVTPTPGSVGGSTGP 299
Query: 425 GAGAT 429
A A+
Sbjct: 300 SAAAS 304
>gi|61835232 growth differentiation factor 7 preproprotein [Homo
sapiens]
Length = 450
Score = 32.7 bits (73), Expect = 0.71
Identities = 15/25 (60%), Positives = 15/25 (60%)
Query: 402 GGGDRGGGGGRVALTAPGAADAPGA 426
GGG GGGGGR A GAA P A
Sbjct: 41 GGGGGGGGGGRTLAQAAGAAAVPAA 65
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/56 (35%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Query: 377 FAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGI 432
F P +A A AA A T GG GGG GGGGG G G+ +
Sbjct: 55 FRPEPIASA--AAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNL 108
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/56 (35%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Query: 377 FAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGI 432
F P +A A AA A T GG GGG GGGGG G G+ +
Sbjct: 55 FRPEPIASA--AAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNL 108
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 32.3 bits (72), Expect = 0.93
Identities = 20/56 (35%), Positives = 23/56 (41%), Gaps = 2/56 (3%)
Query: 377 FAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAGI 432
F P +A A AA A T GG GGG GGGGG G G+ +
Sbjct: 55 FRPEPIASA--AAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNL 108
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 32.3 bits (72), Expect = 0.93
Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 11/55 (20%)
Query: 399 GDSGGGDRGGGGGRVALTAPGAADAPGAGATAG------IHWYSQLLYQIGTWLL 447
G SGGG GGGGG GA P A A W+ LL + TWLL
Sbjct: 428 GSSGGGGSGGGGG-----VGGAGGGPWGPAPAWCPCGSCCSWWKWLLGLLLTWLL 477
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 32.3 bits (72), Expect = 0.93
Identities = 18/33 (54%), Positives = 18/33 (54%), Gaps = 7/33 (21%)
Query: 398 GGDSGGGDRGGGGGRVALTAPGAADAPGAGATA 430
GG GGG GGGGG G A A GAGA A
Sbjct: 255 GGGGGGGSGGGGGG-------GGAGAGGAGAGA 280
Score = 32.0 bits (71), Expect = 1.2
Identities = 16/34 (47%), Positives = 16/34 (47%)
Query: 398 GGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
GG G G G G G VA A AA A G G G
Sbjct: 266 GGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGG 299
Score = 31.6 bits (70), Expect = 1.6
Identities = 16/34 (47%), Positives = 17/34 (50%)
Query: 398 GGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
GG GGG GG G A+ A AA A AG G
Sbjct: 264 GGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGG 297
Score = 31.6 bits (70), Expect = 1.6
Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 5/55 (9%)
Query: 383 AHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAP-----GAADAPGAGATAGI 432
A A+ AA A A GG GGG G G L++P G PG G A +
Sbjct: 278 AGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASL 332
Score = 29.6 bits (65), Expect = 6.0
Identities = 16/35 (45%), Positives = 17/35 (48%)
Query: 397 RGGDSGGGDRGGGGGRVALTAPGAADAPGAGATAG 431
R G GGG GGGGG + G A GA AG
Sbjct: 245 RPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAG 279
>gi|40255016 membrane-associated RING-CH protein IX [Homo sapiens]
Length = 346
Score = 32.3 bits (72), Expect = 0.93
Identities = 23/64 (35%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 366 VIEEHSWAHRAFAPFRLAHALLAALAPART-DRGGDSGGGDRGGGGGRVALTAP--GAAD 422
+I E S +R F ++ + L +T D GGD+GGG G G R + T P GA
Sbjct: 238 IIHEGSSVYRIFKRWQAVNQQWKVLNYDKTKDIGGDAGGGTAGKSGPRNSRTGPTSGATS 297
Query: 423 APGA 426
P A
Sbjct: 298 RPPA 301
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,909,724
Number of Sequences: 37866
Number of extensions: 925054
Number of successful extensions: 7404
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 76
Number of HSP's successfully gapped in prelim test: 64
Number of HSP's that attempted gapping in prelim test: 6394
Number of HSP's gapped (non-prelim): 743
length of query: 462
length of database: 18,247,518
effective HSP length: 106
effective length of query: 356
effective length of database: 14,233,722
effective search space: 5067205032
effective search space used: 5067205032
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.