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Search of human proteins with 4506105
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506105 prolactin precursor [Homo sapiens]
(227 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506105 prolactin precursor [Homo sapiens] 461 e-130
gi|13027812 growth hormone 1 isoform 1 [Homo sapiens] 75 4e-14
gi|13027814 growth hormone 1 isoform 2 [Homo sapiens] 72 3e-13
gi|4503083 chorionic somatomammotropin hormone 1 isoform 1 [Homo... 69 3e-12
gi|10334861 chorionic somatomammotropin hormone 2 isoform 1 [Hom... 69 3e-12
gi|4503991 growth hormone 2 isoform 1 [Homo sapiens] 64 1e-10
gi|13027822 growth hormone 2 isoform 4 [Homo sapiens] 61 9e-10
gi|12545376 chorionic somatomammotropin hormone-like 1 isoform 1... 56 2e-08
gi|12408685 chorionic somatomammotropin hormone 1 isoform 2 [Hom... 54 8e-08
gi|12408692 chorionic somatomammotropin hormone 2 isoform 2 [Hom... 54 8e-08
gi|12545381 chorionic somatomammotropin hormone-like 1 isoform 2... 54 8e-08
gi|13027826 growth hormone 2 isoform 3 [Homo sapiens] 46 2e-05
gi|13027824 growth hormone 2 isoform 2 [Homo sapiens] 46 2e-05
gi|13027816 growth hormone 1 isoform 3 [Homo sapiens] 46 3e-05
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 41 0.001
gi|12545378 chorionic somatomammotropin hormone-like 1 isoform 4... 39 0.005
gi|38201628 chorionic somatomammotropin hormone-like 1 isoform 3... 36 0.024
gi|48928019 Nedd4 binding protein 1 [Homo sapiens] 35 0.069
gi|13027818 growth hormone 1 isoform 4 [Homo sapiens] 34 0.12
gi|239756908 PREDICTED: similar to chorionic somatomammotropin h... 34 0.12
gi|12408687 chorionic somatomammotropin hormone 1 isoform 3 [Hom... 34 0.12
gi|12408694 chorionic somatomammotropin hormone 2 isoform 3 [Hom... 34 0.12
gi|153792110 HEG homolog 1 [Homo sapiens] 32 0.58
gi|110347463 human immunodeficiency virus type I enhancer bindin... 31 0.99
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap... 30 2.2
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 30 2.2
gi|150417973 supervillin isoform 2 [Homo sapiens] 29 2.9
gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105k... 29 2.9
gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105k... 29 2.9
gi|58865339 defensin, beta 121 [Homo sapiens] 29 2.9
>gi|4506105 prolactin precursor [Homo sapiens]
Length = 227
Score = 461 bits (1185), Expect = e-130
Identities = 227/227 (100%), Positives = 227/227 (100%)
Query: 1 MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL 60
MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL
Sbjct: 1 MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNL 60
Query: 61 SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN 120
SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN
Sbjct: 61 SSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN 120
Query: 121 EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG 180
EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG
Sbjct: 121 EPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSG 180
Query: 181 LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC 227
LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC
Sbjct: 181 LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC 227
>gi|13027812 growth hormone 1 isoform 1 [Homo sapiens]
Length = 217
Score = 75.5 bits (184), Expect = 4e-14
Identities = 56/222 (25%), Positives = 110/222 (49%), Gaps = 17/222 (7%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP G+A + L LFD A++ +H +H L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFE 58
Query: 70 KRY---THGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ S C + S+ TP ++E+ QQ + + L + + +++SW EP+
Sbjct: 59 EAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQF 118
Query: 126 LVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHP-ETKENEIY-PVWSGLPS 183
L R + + + + K L EG++ ++ ++ + +I+ +S +
Sbjct: 119 L----RSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDT 174
Query: 184 LQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
D+ L Y LL+C R+D K++ +L++++CR + +
Sbjct: 175 NSHNDD--ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGS 214
>gi|13027814 growth hormone 1 isoform 2 [Homo sapiens]
Length = 202
Score = 72.4 bits (176), Expect = 3e-13
Identities = 53/218 (24%), Positives = 107/218 (49%), Gaps = 24/218 (11%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP G+A + L LFD A++ +H +H L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFN 58
Query: 70 KRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTE 129
+ + C + S+ TP ++E+ QQ + + L + + +++SW EP+ L
Sbjct: 59 PQ-----------TSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFL--- 104
Query: 130 VRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHP-ETKENEIY-PVWSGLPSLQMA 187
R + + + + K L EG++ ++ ++ + +I+ +S +
Sbjct: 105 -RSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHN 163
Query: 188 DEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
D+ L Y LL+C R+D K++ +L++++CR + +
Sbjct: 164 DD--ALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGS 199
>gi|4503083 chorionic somatomammotropin hormone 1 isoform 1 [Homo
sapiens]
Length = 217
Score = 69.3 bits (168), Expect = 3e-12
Identities = 54/220 (24%), Positives = 100/220 (45%), Gaps = 13/220 (5%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF+
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFE 58
Query: 70 KRYT---HGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ + S C + S+ TP + E+ QQ + + L + + ++ SW EP+
Sbjct: 59 ETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRF 118
Query: 126 LVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQ 185
L R M + + K L EG++ ++ ++ ++ +
Sbjct: 119 L----RSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDT 174
Query: 186 MADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+ L Y LL+C R+D K++ +L++++CR + +
Sbjct: 175 NSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGS 214
>gi|10334861 chorionic somatomammotropin hormone 2 isoform 1 [Homo
sapiens]
Length = 217
Score = 69.3 bits (168), Expect = 3e-12
Identities = 54/220 (24%), Positives = 100/220 (45%), Gaps = 13/220 (5%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF+
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFE 58
Query: 70 KRYT---HGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ + S C + S+ TP + E+ QQ + + L + + ++ SW EP+
Sbjct: 59 ETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRF 118
Query: 126 LVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQ 185
L R M + + K L EG++ ++ ++ ++ +
Sbjct: 119 L----RSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDT 174
Query: 186 MADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+ L Y LL+C R+D K++ +L++++CR + +
Sbjct: 175 NSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGS 214
>gi|4503991 growth hormone 2 isoform 1 [Homo sapiens]
Length = 217
Score = 63.9 bits (154), Expect = 1e-10
Identities = 53/225 (23%), Positives = 106/225 (47%), Gaps = 23/225 (10%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC L G+A + L LFD A++ + ++ L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFE 58
Query: 70 KRYT---HGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ S C + S+ TP ++ + QQ + + L + + +++SW EP+
Sbjct: 59 EAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQL 118
Query: 126 LVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVH---PETKE--NEIYPVWSG 180
L R + + + K L EG++ ++ ++ P T + N+ Y +
Sbjct: 119 L----RSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFD- 173
Query: 181 LPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+ + L Y LL+C R+D K++ +L++++CR + +
Sbjct: 174 ----TKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGS 214
>gi|13027822 growth hormone 2 isoform 4 [Homo sapiens]
Length = 202
Score = 60.8 bits (146), Expect = 9e-10
Identities = 50/221 (22%), Positives = 103/221 (46%), Gaps = 30/221 (13%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC L G+A + L LFD A++ + ++ L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFN 58
Query: 70 KRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTE 129
+ + C + S+ TP ++ + QQ + + L + + +++SW EP+ L
Sbjct: 59 PQ-----------TSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPVQLL--- 104
Query: 130 VRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVH---PETKE--NEIYPVWSGLPSL 184
R + + + K L EG++ ++ ++ P T + N+ Y +
Sbjct: 105 -RSVFANSLVYGASDSNVYRHLKDLEEGIQTLMWRLEDGSPRTGQIFNQSYSKFD----- 158
Query: 185 QMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+ + L Y LL+C R+D K++ +L++++CR + +
Sbjct: 159 TKSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGS 199
>gi|12545376 chorionic somatomammotropin hormone-like 1 isoform 1
precursor [Homo sapiens]
Length = 222
Score = 56.2 bits (134), Expect = 2e-08
Identities = 57/236 (24%), Positives = 100/236 (42%), Gaps = 40/236 (16%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LF A++ +H H L+ + + EF
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEFI 58
Query: 70 KRYTHGRGFITKA----------INSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSW 119
+ +ITK + C + S+ T + E+ QQ + + L + + ++ S
Sbjct: 59 SSWGM-EAYITKEQKYSFLHDSQTSFCFSDSIPTSSNMEETQQKSNLELLHISLLLIESR 117
Query: 120 NEPLYHLVTE-----VRGMQEAPEAILSKAVE--IEEQTKRLLEGMELI---VSQVHPET 169
EP+ L + V ++ + L K +E I+ RL +G L + Q + +
Sbjct: 118 LEPVRFLRSTFTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKF 177
Query: 170 KENEIYPVWSGLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
N + L Y LLHC R+D K++ +L++++CR + +
Sbjct: 178 DTN--------------SHNHDALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGS 219
>gi|12408685 chorionic somatomammotropin hormone 1 isoform 2 [Homo
sapiens]
Length = 256
Score = 54.3 bits (129), Expect = 8e-08
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF+
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFE 58
Query: 70 KRY---THGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ + S C + S+ TP + E+ QQ + + L + + ++ SW EP+
Sbjct: 59 ETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRF 118
Query: 126 L 126
L
Sbjct: 119 L 119
>gi|12408692 chorionic somatomammotropin hormone 2 isoform 2 [Homo
sapiens]
Length = 167
Score = 54.3 bits (129), Expect = 8e-08
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 9/121 (7%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF+
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFE 58
Query: 70 KRY---THGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYH 125
+ Y F+ + S C + S+ TP + E+ QQ + + L + + ++ SW EP+
Sbjct: 59 ETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRF 118
Query: 126 L 126
L
Sbjct: 119 L 119
>gi|12545381 chorionic somatomammotropin hormone-like 1 isoform 2
precursor [Homo sapiens]
Length = 199
Score = 54.3 bits (129), Expect = 8e-08
Identities = 55/226 (24%), Positives = 95/226 (42%), Gaps = 43/226 (19%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP A V L LF A++ +H H L+ + + EF
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFKEAMLQAHRAHQLAIDTYQEF- 57
Query: 70 KRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTE 129
I+S S+ T + E+ QQ + + L + + ++ S EP+ L +
Sbjct: 58 -------------ISSWGMDSIPTSSNMEETQQKSNLELLHISLLLIESRLEPVRFLRST 104
Query: 130 -----VRGMQEAPEAILSKAVE--IEEQTKRLLEGMELI---VSQVHPETKENEIYPVWS 179
V ++ + L K +E I+ RL +G L + Q + + N
Sbjct: 105 FTNNLVYDTSDSDDYHLLKDLEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTN------- 157
Query: 180 GLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+ L Y LLHC R+D K++ +L++++CR + +
Sbjct: 158 -------SHNHDALLKNYGLLHCFRKDMDKVETFLRMVQCRSVEGS 196
>gi|13027826 growth hormone 2 isoform 3 [Homo sapiens]
Length = 245
Score = 46.2 bits (108), Expect = 2e-05
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC L G+A + L LFD A++ + ++ L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFE 58
Query: 70 KRYT---HGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPL 123
+ Y F+ S C + S+ TP ++ + QQ + + L + + +++SW EP+
Sbjct: 59 EAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPV 116
>gi|13027824 growth hormone 2 isoform 2 [Homo sapiens]
Length = 256
Score = 46.2 bits (108), Expect = 2e-05
Identities = 32/118 (27%), Positives = 60/118 (50%), Gaps = 9/118 (7%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC L G+A + L LFD A++ + ++ L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LSWLQEGSAFPTIPLSRLFDNAMLRARRLYQLAYDTYQEFE 58
Query: 70 KRYT---HGRGFITKAINS-CHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPL 123
+ Y F+ S C + S+ TP ++ + QQ + + L + + +++SW EP+
Sbjct: 59 EAYILKEQKYSFLQNPQTSLCFSESIPTPSNRVKTQQKSNLELLRISLLLIQSWLEPV 116
>gi|13027816 growth hormone 1 isoform 3 [Homo sapiens]
Length = 177
Score = 45.8 bits (107), Expect = 3e-05
Identities = 44/217 (20%), Positives = 92/217 (42%), Gaps = 47/217 (21%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFD 69
GS LL++ LLC LP G+A + L LFD A++ +H +H L+ + + EF+
Sbjct: 4 GSRTSLLLAFGLLC-----LPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFN 58
Query: 70 KRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTE 129
+ L + + +++SW EP+ L
Sbjct: 59 L------------------------------------ELLRISLLLIQSWLEPVQFL--- 79
Query: 130 VRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPET-KENEIYPVWSGLPSLQMAD 188
R + + + + K L EG++ ++ ++ + + +I+ +
Sbjct: 80 -RSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHN 138
Query: 189 EESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
+++ L Y LL+C R+D K++ +L++++CR + +
Sbjct: 139 DDALLKNY-GLLYCFRKDMDKVETFLRIVQCRSVEGS 174
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 40.8 bits (94), Expect = 0.001
Identities = 31/126 (24%), Positives = 63/126 (50%), Gaps = 12/126 (9%)
Query: 80 TKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWN--EPLYHLVTEVRG-MQEA 136
T + ++C S +++ D+E A+ + + F ++V +L + +Y + E +QE
Sbjct: 821 TSSSDTCQKSFVSSCTDEEPAEPEDMERFEEMVVKVLIKLQAVQAMYQISQEEHSQLQEQ 880
Query: 137 PEAILSKAVEIEEQ----TKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQM-----A 187
E +L+K +++E+ + E ME + + P+ +NEI + + L LQ+
Sbjct: 881 MEKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKNEIKELQTKLRELQLQYQASM 940
Query: 188 DEESRL 193
DE+ RL
Sbjct: 941 DEQGRL 946
>gi|12545378 chorionic somatomammotropin hormone-like 1 isoform 4
[Homo sapiens]
Length = 139
Score = 38.5 bits (88), Expect = 0.005
Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 24/146 (16%)
Query: 90 SLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTE-----VRGMQEAPEAILSKA 144
S+ T + E+ QQ + + L + + ++ S EP+ L + V ++ + L K
Sbjct: 5 SIPTSSNMEETQQKSNLELLHISLLLIESRLEPVRFLRSTFTNNLVYDTSDSDDYHLLKD 64
Query: 145 VE--IEEQTKRLLEGMELI---VSQVHPETKENEIYPVWSGLPSLQMADEESRLSAYYNL 199
+E I+ RL +G L + Q + + N + L Y L
Sbjct: 65 LEEGIQMLMGRLEDGSHLTGQTLKQTYSKFDTN--------------SHNHDALLKNYGL 110
Query: 200 LHCLRRDSHKIDNYLKLLKCRIIHNN 225
LHC R+D K++ +L++++CR + +
Sbjct: 111 LHCFRKDMDKVETFLRMVQCRSVEGS 136
>gi|38201628 chorionic somatomammotropin hormone-like 1 isoform 3
[Homo sapiens]
Length = 128
Score = 36.2 bits (82), Expect = 0.024
Identities = 11/29 (37%), Positives = 21/29 (72%)
Query: 197 YNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
Y LLHC R+D K++ +L++++CR + +
Sbjct: 97 YGLLHCFRKDMDKVETFLRMVQCRSVEGS 125
>gi|48928019 Nedd4 binding protein 1 [Homo sapiens]
Length = 896
Score = 34.7 bits (78), Expect = 0.069
Identities = 31/140 (22%), Positives = 59/140 (42%), Gaps = 7/140 (5%)
Query: 84 NSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSK 143
+S S +P+ KE ++M ++ ++ +++ + V +V G P +L
Sbjct: 326 DSSADSENLSPDIKETTEEMEYNILVNFFKTM--GYSQEIVEKVIKVYGPSTEPLLLLE- 382
Query: 144 AVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQMADEESRLSAY--YNLLH 201
EIE++ KR E E V+PET + + V+S L + A+ N++
Sbjct: 383 --EIEKENKRFQEDREFSAGTVYPETNKTKNKGVYSSTNELTTDSTPKKTQAHTQQNMVE 440
Query: 202 CLRRDSHKIDNYLKLLKCRI 221
+ K++ CRI
Sbjct: 441 KFSQLPFKVEAKPCTSNCRI 460
>gi|13027818 growth hormone 1 isoform 4 [Homo sapiens]
Length = 122
Score = 33.9 bits (76), Expect = 0.12
Identities = 10/29 (34%), Positives = 21/29 (72%)
Query: 197 YNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
Y LL+C R+D K++ +L++++CR + +
Sbjct: 91 YGLLYCFRKDMDKVETFLRIVQCRSVEGS 119
Score = 33.5 bits (75), Expect = 0.15
Identities = 21/59 (35%), Positives = 32/59 (54%), Gaps = 5/59 (8%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEF 68
GS LL++ LLC LP G+A + L LFD A++ +H +H L+ + + EF
Sbjct: 4 GSRTSLLLAFGLLC-----LPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEF 57
>gi|239756908 PREDICTED: similar to chorionic somatomammotropin
hormone 2 [Homo sapiens]
Length = 96
Score = 33.9 bits (76), Expect = 0.12
Identities = 10/29 (34%), Positives = 21/29 (72%)
Query: 197 YNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
Y LL+C R+D K++ +L++++CR + +
Sbjct: 65 YGLLYCFRKDMDKVETFLRMVQCRSVEGS 93
>gi|12408687 chorionic somatomammotropin hormone 1 isoform 3 [Homo
sapiens]
Length = 122
Score = 33.9 bits (76), Expect = 0.12
Identities = 10/29 (34%), Positives = 21/29 (72%)
Query: 197 YNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
Y LL+C R+D K++ +L++++CR + +
Sbjct: 91 YGLLYCFRKDMDKVETFLRMVQCRSVEGS 119
Score = 31.2 bits (69), Expect = 0.76
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEF 68
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEF 57
>gi|12408694 chorionic somatomammotropin hormone 2 isoform 3 [Homo
sapiens]
Length = 122
Score = 33.9 bits (76), Expect = 0.12
Identities = 10/29 (34%), Positives = 21/29 (72%)
Query: 197 YNLLHCLRRDSHKIDNYLKLLKCRIIHNN 225
Y LL+C R+D K++ +L++++CR + +
Sbjct: 91 YGLLYCFRKDMDKVETFLRMVQCRSVEGS 119
Score = 31.2 bits (69), Expect = 0.76
Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 5/59 (8%)
Query: 10 GSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEF 68
GS LL++ LLC LP A V L LFD A++ +H H L+ + + EF
Sbjct: 4 GSRTSLLLAFALLC-----LPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEF 57
>gi|153792110 HEG homolog 1 [Homo sapiens]
Length = 1381
Score = 31.6 bits (70), Expect = 0.58
Identities = 25/89 (28%), Positives = 42/89 (47%), Gaps = 15/89 (16%)
Query: 109 LSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSK----------AVEIEEQ--TKRLLE 156
++LIV+ R + L+ + Q +P A K A+E+ E TK LL+
Sbjct: 1266 IALIVTCCRKNKNDISKLIFKSGDFQMSPYAEYPKNPRSQEWGREAIEMHENGSTKNLLQ 1325
Query: 157 GMELIVSQV---HPETKENEIYPVWSGLP 182
++ S +PE + N +YP ++GLP
Sbjct: 1326 MTDVYYSPTSVRNPELERNGLYPAYTGLP 1354
>gi|110347463 human immunodeficiency virus type I enhancer binding
protein 2 [Homo sapiens]
Length = 2446
Score = 30.8 bits (68), Expect = 0.99
Identities = 30/138 (21%), Positives = 57/138 (41%), Gaps = 26/138 (18%)
Query: 74 HGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRS--------------- 118
H + + K + + S TP ++Q+ Q+DF S L+S
Sbjct: 1289 HPKNLLPKFPSDQSSKSTETP-----SEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVP 1343
Query: 119 -WNEPLYHLVTEVRGMQEAPEAILSKAVEIEEQ----TKRLLEGMELIVSQVHPETKENE 173
+ +Y ++++ G Q +P ++ K E Q T ++G+ ++QV + E
Sbjct: 1344 SYGSVMYTSISQILG-QNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLE 1402
Query: 174 IYPVWSGLPSLQMADEES 191
YP+W +L + E S
Sbjct: 1403 KYPIWKAPQTLPLGLESS 1420
>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sapiens]
Length = 1503
Score = 29.6 bits (65), Expect = 2.2
Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 14/84 (16%)
Query: 95 EDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRL 154
E +E Q +N +F+SL++ + LVTE Q+ SK++E+E K +
Sbjct: 1334 ELQESIQLLNSMEFVSLLLYD--------HTLVTEPNSPQD------SKSMELEANVKLV 1379
Query: 155 LEGMELIVSQVHPETKENEIYPVW 178
+ ++ ++ HPE + + + W
Sbjct: 1380 RDILKAVILFFHPELEFSSDFGSW 1403
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 29.6 bits (65), Expect = 2.2
Identities = 27/120 (22%), Positives = 51/120 (42%), Gaps = 6/120 (5%)
Query: 51 VVLSHYIHNLSSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLS 110
V++S Y + +M ++++ T R + ++S HT + PE+ + D L
Sbjct: 369 VLMSRYHRRKAQQMTQKYEEELTLTRENSIRRLHSHHTDPRSQPEESVGLRAEGHPDSLK 428
Query: 111 LIVSILRSWNEP---LYHLVTEVRGMQEAPEAI---LSKAVEIEEQTKRLLEGMELIVSQ 164
S EP Y +T VR ++ E + +A E E+Q + + + M V +
Sbjct: 429 DNSSCSVMSEEPEGRSYSTLTTVREIETQTELLSPGSGRAEEEEDQDEGIKQAMNHFVQE 488
>gi|150417973 supervillin isoform 2 [Homo sapiens]
Length = 2214
Score = 29.3 bits (64), Expect = 2.9
Identities = 29/113 (25%), Positives = 48/113 (42%), Gaps = 17/113 (15%)
Query: 76 RGFITKAINSCHTSSLATPEDKEQAQQ--------MNQKDFLSLIVSILRSWNEPLYHLV 127
RG++ A ++ HT+ L TPE E A + N SL V + P+ H+
Sbjct: 365 RGYVQPA-DTGHTAKLVTPETPENASECSWVASATQNVPKPPSLTVLEGDGRDSPVLHVC 423
Query: 128 T--------EVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKEN 172
E G ++ + ++A+E ++T LEG L+ S P E+
Sbjct: 424 ESKAEEEEGEGEGEEKEEDVCFTEALEQSKKTLLALEGDGLVRSPEDPSRNED 476
>gi|156104897 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 29.3 bits (64), Expect = 2.9
Identities = 11/25 (44%), Positives = 17/25 (68%)
Query: 196 YYNLLHCLRRDSHKIDNYLKLLKCR 220
+ L C+RR+ +I+N LK +KCR
Sbjct: 872 FIRALDCMRREGCRIENVLKNIKCR 896
>gi|156104895 inositol polyphosphate-4-phosphatase, type II, 105kD
[Homo sapiens]
Length = 924
Score = 29.3 bits (64), Expect = 2.9
Identities = 11/25 (44%), Positives = 17/25 (68%)
Query: 196 YYNLLHCLRRDSHKIDNYLKLLKCR 220
+ L C+RR+ +I+N LK +KCR
Sbjct: 872 FIRALDCMRREGCRIENVLKNIKCR 896
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 29.3 bits (64), Expect = 2.9
Identities = 14/34 (41%), Positives = 21/34 (61%)
Query: 12 LLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRD 45
LLLLL++ LL V P+ C G + RC+ T ++
Sbjct: 3 LLLLLLTVTLLLAQVTPVMKCWGKSGRCRTTCKE 36
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,567,800
Number of Sequences: 37866
Number of extensions: 348318
Number of successful extensions: 1170
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1117
Number of HSP's gapped (non-prelim): 45
length of query: 227
length of database: 18,247,518
effective HSP length: 99
effective length of query: 128
effective length of database: 14,498,784
effective search space: 1855844352
effective search space used: 1855844352
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.