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Search of human proteins with 4505735
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505735 platelet factor 4 variant 1 [Homo sapiens]
(104 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505735 platelet factor 4 variant 1 [Homo sapiens] 203 2e-53
gi|4505733 platelet factor 4 (chemokine (C-X-C motif) ligand 4) ... 163 2e-41
gi|4504153 chemokine (C-X-C motif) ligand 1 [Homo sapiens] 75 1e-14
gi|4505981 pro-platelet basic protein precursor [Homo sapiens] 75 1e-14
gi|4506849 chemokine (C-X-C motif) ligand 5 precursor [Homo sapi... 71 2e-13
gi|4506851 chemokine (C-X-C motif) ligand 6 (granulocyte chemota... 69 1e-12
gi|4504155 chemokine (C-X-C motif) ligand 2 [Homo sapiens] 69 1e-12
gi|54144650 chemokine (C-X-C motif) ligand 3 [Homo sapiens] 64 2e-11
gi|10834978 interleukin 8 precursor [Homo sapiens] 55 9e-09
gi|221219042 pro-platelet basic protein-like 1 [Homo sapiens] 48 2e-06
gi|149999382 small inducible cytokine B10 precursor [Homo sapiens] 46 5e-06
gi|4505187 small inducible cytokine B9 precursor [Homo sapiens] 40 3e-04
gi|5453577 chemokine (C-X-C motif) ligand 13 (B-cell chemoattrac... 37 0.004
gi|20149565 small inducible cytokine B14 precursor [Homo sapiens] 34 0.022
gi|4506831 small inducible cytokine A18 precursor [Homo sapiens] 34 0.028
gi|169201839 PREDICTED: similar to hCG2038970 [Homo sapiens] 29 0.91
gi|169201482 PREDICTED: similar to hCG2038970 [Homo sapiens] 29 0.91
gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo sap... 27 3.4
gi|57528101 hypothetical protein LOC728130 [Homo sapiens] 27 3.4
gi|150170710 hypothetical protein LOC728118 [Homo sapiens] 27 3.4
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 27 4.5
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 27 4.5
gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Hom... 27 4.5
gi|31317307 proprotein convertase subtilisin/kexin type 9 prepro... 26 5.9
>gi|4505735 platelet factor 4 variant 1 [Homo sapiens]
Length = 104
Score = 203 bits (517), Expect = 2e-53
Identities = 104/104 (100%), Positives = 104/104 (100%)
Query: 1 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS 60
MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS
Sbjct: 1 MSSAARSRLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITS 60
Query: 61 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES
Sbjct: 61 LEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
>gi|4505733 platelet factor 4 (chemokine (C-X-C motif) ligand 4)
[Homo sapiens]
Length = 101
Score = 163 bits (413), Expect = 2e-41
Identities = 83/93 (89%), Positives = 87/93 (93%)
Query: 12 ATRQEMLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCP 71
A+R +LFL LLLLP+VVAFA AEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCP
Sbjct: 9 ASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCP 68
Query: 72 TAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
TAQLIATLKNGRKICLDLQA LYKKIIK+ LES
Sbjct: 69 TAQLIATLKNGRKICLDLQAPLYKKIIKKLLES 101
>gi|4504153 chemokine (C-X-C motif) ligand 1 [Homo sapiens]
Length = 107
Score = 74.7 bits (182), Expect = 1e-14
Identities = 44/102 (43%), Positives = 65/102 (63%), Gaps = 2/102 (1%)
Query: 5 ARSRLTRA-TRQEMLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHITSLE 62
AR+ L+ A + +L +ALLLL +V A RA A +L+C C++T + P++I S+
Sbjct: 2 ARAALSAAPSNPRLLRVALLLLLLVAAGRRAAGASVATELRCQCLQTLQGIHPKNIQSVN 61
Query: 63 VIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
V GPHC ++IATLKNGRK CL+ + + KKII++ L S
Sbjct: 62 VKSPGPHCAQTEVIATLKNGRKACLNPASPIVKKIIEKMLNS 103
>gi|4505981 pro-platelet basic protein precursor [Homo sapiens]
Length = 128
Score = 74.7 bits (182), Expect = 1e-14
Identities = 34/62 (54%), Positives = 47/62 (75%)
Query: 41 DLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKE 100
+L+C+C+KTTS + P++I SLEVI G HC ++IATLK+GRKICLD A KKI+++
Sbjct: 60 ELRCMCIKTTSGIHPKNIQSLEVIGKGTHCNQVEVIATLKDGRKICLDPDAPRIKKIVQK 119
Query: 101 HL 102
L
Sbjct: 120 KL 121
>gi|4506849 chemokine (C-X-C motif) ligand 5 precursor [Homo
sapiens]
Length = 114
Score = 71.2 bits (173), Expect = 2e-13
Identities = 34/87 (39%), Positives = 57/87 (65%)
Query: 17 MLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLI 76
++ L LL P +A A A +L+C+C++TT V P+ I++L+V GP C +++
Sbjct: 22 LVLLLLLTQPGPIASAGPAAAVLRELRCVCLQTTQGVHPKMISNLQVFAIGPQCSKVEVV 81
Query: 77 ATLKNGRKICLDLQALLYKKIIKEHLE 103
A+LKNG++ICLD +A KK+I++ L+
Sbjct: 82 ASLKNGKEICLDPEAPFLKKVIQKILD 108
>gi|4506851 chemokine (C-X-C motif) ligand 6 (granulocyte
chemotactic protein 2) [Homo sapiens]
Length = 114
Score = 68.6 bits (166), Expect = 1e-12
Identities = 38/107 (35%), Positives = 64/107 (59%), Gaps = 3/107 (2%)
Query: 1 MSSAARSRLTRATRQEMLFLALLLL---PVVVAFARAEAEEDGDLQCLCVKTTSQVRPRH 57
+ S+ +R+ + LALLLL P +A A + +L+C C++ T +V P+
Sbjct: 3 LPSSRAARVPGPSGSLCALLALLLLLTPPGPLASAGPVSAVLTELRCTCLRVTLRVNPKT 62
Query: 58 ITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
I L+V AGP C +++A+LKNG+++CLD +A KK+I++ L+S
Sbjct: 63 IGKLQVFPAGPQCSKVEVVASLKNGKQVCLDPEAPFLKKVIQKILDS 109
>gi|4504155 chemokine (C-X-C motif) ligand 2 [Homo sapiens]
Length = 107
Score = 68.6 bits (166), Expect = 1e-12
Identities = 41/102 (40%), Positives = 66/102 (64%), Gaps = 2/102 (1%)
Query: 5 ARSRLTRA-TRQEMLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHITSLE 62
AR+ L+ A + +L +ALLLL +V A RA A +L+C C++T + ++I S++
Sbjct: 2 ARATLSAAPSNPRLLRVALLLLLLVAASRRAAGAPLATELRCQCLQTLQGIHLKNIQSVK 61
Query: 63 VIKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLES 104
V GPHC ++IATLKNG+K CL+ + + KKII++ L++
Sbjct: 62 VKSPGPHCAQTEVIATLKNGQKACLNPASPMVKKIIEKMLKN 103
>gi|54144650 chemokine (C-X-C motif) ligand 3 [Homo sapiens]
Length = 107
Score = 64.3 bits (155), Expect = 2e-11
Identities = 36/87 (41%), Positives = 56/87 (64%), Gaps = 1/87 (1%)
Query: 17 MLFLALLLLPVVVAFARAE-AEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQL 75
+L +ALLLL +V A RA A +L+C C++T + ++I S+ V GPHC ++
Sbjct: 15 LLRVALLLLLLVAASRRAAGASVVTELRCQCLQTLQGIHLKNIQSVNVRSPGPHCAQTEV 74
Query: 76 IATLKNGRKICLDLQALLYKKIIKEHL 102
IATLKNG+K CL+ + + +KII++ L
Sbjct: 75 IATLKNGKKACLNPASPMVQKIIEKIL 101
>gi|10834978 interleukin 8 precursor [Homo sapiens]
Length = 99
Score = 55.5 bits (132), Expect = 9e-09
Identities = 26/85 (30%), Positives = 48/85 (56%), Gaps = 1/85 (1%)
Query: 20 LALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQ-VRPRHITSLEVIKAGPHCPTAQLIAT 78
LA L+ + +L+C C+KT S+ P+ I L VI++GPHC ++I
Sbjct: 10 LAAFLISAALCEGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVK 69
Query: 79 LKNGRKICLDLQALLYKKIIKEHLE 103
L +GR++CLD + ++++++ L+
Sbjct: 70 LSDGRELCLDPKENWVQRVVEKFLK 94
>gi|221219042 pro-platelet basic protein-like 1 [Homo sapiens]
Length = 126
Score = 47.8 bits (112), Expect = 2e-06
Identities = 33/100 (33%), Positives = 57/100 (57%), Gaps = 12/100 (12%)
Query: 16 EMLFLALLLLPVVVAFARAEAE------EDGDLQ----CLCVKTTSQVRPRHIT-SLEV- 63
++L L LLL + + +++ +D DL C+CVK+ S + P +I ++ +
Sbjct: 21 QVLLLLSLLLTALPSCTNGQSKRNLGKSKDSDLYIELCCVCVKSASGIHPSNIIPNIHIY 80
Query: 64 IKAGPHCPTAQLIATLKNGRKICLDLQALLYKKIIKEHLE 103
+ +G C Q+IA LK+GRK+ LD +A KKI+++ LE
Sbjct: 81 LLSGAPCNKVQVIAMLKDGRKMYLDPEAPRIKKIVQKMLE 120
>gi|149999382 small inducible cytokine B10 precursor [Homo
sapiens]
Length = 98
Score = 46.2 bits (108), Expect = 5e-06
Identities = 22/60 (36%), Positives = 37/60 (61%), Gaps = 2/60 (3%)
Query: 42 LQCLCVKTTSQ-VRPRHITSLEVIKAGPHCPTAQLIATL-KNGRKICLDLQALLYKKIIK 99
++C C+ ++Q V PR + LE+I A CP ++IAT+ K G K CL+ ++ K ++K
Sbjct: 28 VRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLK 87
>gi|4505187 small inducible cytokine B9 precursor [Homo sapiens]
Length = 125
Score = 40.4 bits (93), Expect = 3e-04
Identities = 27/87 (31%), Positives = 45/87 (51%), Gaps = 7/87 (8%)
Query: 17 MLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKA---GPHCPTA 73
+LFL ++L V++ G +C C+ T H+ SL+ +K P C
Sbjct: 6 VLFLLGIILLVLIGVQGTPVVRKG--RCSCISTNQGTI--HLQSLKDLKQFAPSPSCEKI 61
Query: 74 QLIATLKNGRKICLDLQALLYKKIIKE 100
++IATLKNG + CL+ + K++IK+
Sbjct: 62 EIIATLKNGVQTCLNPDSADVKELIKK 88
>gi|5453577 chemokine (C-X-C motif) ligand 13 (B-cell
chemoattractant) [Homo sapiens]
Length = 109
Score = 36.6 bits (83), Expect = 0.004
Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)
Query: 42 LQCLCVKTTSQVRPRH-ITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQA 91
L+C CV+ +S PR I ++++ G CP ++I KN +C+D QA
Sbjct: 31 LRCRCVQESSVFIPRRFIDRIQILPRGNGCPRKEIIVWKKNKSIVCVDPQA 81
>gi|20149565 small inducible cytokine B14 precursor [Homo sapiens]
Length = 111
Score = 34.3 bits (77), Expect = 0.022
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 10/88 (11%)
Query: 17 MLFLALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLI 76
+L ALLLL + + AR + + C C + ++R + LE+ PHC +I
Sbjct: 15 LLAAALLLLLLALYTARVDGSK-----CKCSRKGPKIRYSDVKKLEMKPKYPHCEEKMVI 69
Query: 77 ATLKN-----GRKICLDLQALLYKKIIK 99
T K+ G++ CL + K+ IK
Sbjct: 70 ITTKSVSRYRGQEHCLHPKLQSTKRFIK 97
>gi|4506831 small inducible cytokine A18 precursor [Homo sapiens]
Length = 89
Score = 33.9 bits (76), Expect = 0.028
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 4/83 (4%)
Query: 20 LALLLLPVVVAFARAEAEEDGDLQCLC--VKTTSQVRPRHITSLEVIKAGPHCPTAQLIA 77
LA LL +V A + G + LC V T+ Q+ + I ++ + P CP +I
Sbjct: 4 LAAALLVLVCTMALCSCAQVGTNKELCCLVYTSWQIPQKFI--VDYSETSPQCPKPGVIL 61
Query: 78 TLKNGRKICLDLQALLYKKIIKE 100
K GR+IC D +K I +
Sbjct: 62 LTKRGRQICADPNKKWVQKYISD 84
>gi|169201839 PREDICTED: similar to hCG2038970 [Homo sapiens]
Length = 915
Score = 28.9 bits (63), Expect = 0.91
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
Query: 31 FARAEAEEDGDLQCLCVKTTSQV---RPRHITSLEVIKAGPHCPTAQLIATLK 80
F AEE G ++C+ V T+S+V +P + E ++A P P A+ +ATL+
Sbjct: 520 FPNLGAEEFG-VRCMRVTTSSRVSFQQPSSGAAQEAMEACPLAPNAKTVATLR 571
>gi|169201482 PREDICTED: similar to hCG2038970 [Homo sapiens]
Length = 821
Score = 28.9 bits (63), Expect = 0.91
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 4/53 (7%)
Query: 31 FARAEAEEDGDLQCLCVKTTSQV---RPRHITSLEVIKAGPHCPTAQLIATLK 80
F AEE G ++C+ V T+S+V +P + E ++A P P A+ +ATL+
Sbjct: 520 FPNLGAEEFG-VRCMRVTTSSRVSFQQPSSGAAQEAMEACPLAPNAKTVATLR 571
>gi|169191513 PREDICTED: hypothetical protein isoform 1 [Homo
sapiens]
Length = 878
Score = 26.9 bits (58), Expect = 3.4
Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 8 RLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQ---------CLCVKTTSQVRPRHI 58
R R + F ++ + F EAEE+ +Q CL T ++ PR
Sbjct: 382 RAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 441
Query: 59 TSLEVI--------KAGPHCPTAQL 75
+ EV+ KAGP PTA L
Sbjct: 442 PAPEVVKQPVYLPSKAGPKAPTACL 466
>gi|57528101 hypothetical protein LOC728130 [Homo sapiens]
Length = 557
Score = 26.9 bits (58), Expect = 3.4
Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 8 RLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQ---------CLCVKTTSQVRPRHI 58
R R + F ++ + F EAEE+ +Q CL T ++ PR
Sbjct: 310 RAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 369
Query: 59 TSLEVI--------KAGPHCPTAQL 75
+ EV+ KAGP PTA L
Sbjct: 370 PAPEVVKQPVYLPSKAGPKAPTACL 394
>gi|150170710 hypothetical protein LOC728118 [Homo sapiens]
Length = 878
Score = 26.9 bits (58), Expect = 3.4
Identities = 24/85 (28%), Positives = 34/85 (40%), Gaps = 17/85 (20%)
Query: 8 RLTRATRQEMLFLALLLLPVVVAFARAEAEEDGDLQ---------CLCVKTTSQVRPRHI 58
R R + F ++ + F EAEE+ +Q CL T ++ PR
Sbjct: 382 RAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGP 441
Query: 59 TSLEVI--------KAGPHCPTAQL 75
+ EV+ KAGP PTA L
Sbjct: 442 PAPEVVKQPVYLPSKAGPKAPTACL 466
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens]
Length = 2462
Score = 26.6 bits (57), Expect = 4.5
Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 5/60 (8%)
Query: 30 AFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDL 89
AFA + GD C V PR EVIKA PH P + G + L L
Sbjct: 1025 AFAAEAQKLPGDPPCWTSGLPFPVPPR-----EVIKASPHAPDPSAFSYAPPGHPLPLGL 1079
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 26.6 bits (57), Expect = 4.5
Identities = 20/60 (33%), Positives = 23/60 (38%), Gaps = 5/60 (8%)
Query: 30 AFARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDL 89
AFA + GD C V PR EVIKA PH P + G + L L
Sbjct: 1041 AFAAEAQKLPGDPPCWTSGLPFPVPPR-----EVIKASPHAPDPSAFSYAPPGHPLPLGL 1095
>gi|40255149 Rho guanine nucleotide exchange factor (GEF) 19 [Homo
sapiens]
Length = 802
Score = 26.6 bits (57), Expect = 4.5
Identities = 15/49 (30%), Positives = 22/49 (44%), Gaps = 7/49 (14%)
Query: 32 ARAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLK 80
AR E+E+ + LC + + + EVI G CP Q + T K
Sbjct: 686 ARTESEKQRWISALCPSSPQEDK-------EVISEGEDCPQVQCVRTYK 727
>gi|31317307 proprotein convertase subtilisin/kexin type 9
preproprotein [Homo sapiens]
Length = 692
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/33 (45%), Positives = 21/33 (63%)
Query: 20 LALLLLPVVVAFARAEAEEDGDLQCLCVKTTSQ 52
L LLLL + A ARA+ +EDGD + L + S+
Sbjct: 16 LLLLLLLLGPAGARAQEDEDGDYEELVLALRSE 48
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.134 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,364,957
Number of Sequences: 37866
Number of extensions: 113991
Number of successful extensions: 354
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 337
Number of HSP's gapped (non-prelim): 24
length of query: 104
length of database: 18,247,518
effective HSP length: 75
effective length of query: 29
effective length of database: 15,407,568
effective search space: 446819472
effective search space used: 446819472
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.