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Search of human proteins with 4505571
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4505571 sequestosome 1 isoform 1 [Homo sapiens]
(440 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4505571 sequestosome 1 isoform 1 [Homo sapiens] 919 0.0
gi|214830451 sequestosome 1 isoform 2 [Homo sapiens] 751 0.0
gi|214830438 sequestosome 1 isoform 2 [Homo sapiens] 751 0.0
gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens] 55 1e-07
gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens] 55 1e-07
gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens] 55 1e-07
gi|30348954 mindbomb homolog 1 [Homo sapiens] 48 2e-05
gi|126032348 hect domain and RLD 2 [Homo sapiens] 47 3e-05
gi|21264330 mindbomb homolog 2 [Homo sapiens] 45 1e-04
gi|46852178 potassium channel modulatory factor 1 [Homo sapiens] 44 4e-04
gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sap... 43 5e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 40 0.003
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 40 0.005
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 40 0.005
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 40 0.005
gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens] 39 0.007
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 39 0.009
gi|157364926 dystrotelin [Homo sapiens] 39 0.009
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 39 0.012
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 37 0.027
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 37 0.027
gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens] 37 0.036
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 37 0.047
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 37 0.047
gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens] 37 0.047
gi|55741849 WD repeat domain 22 [Homo sapiens] 36 0.061
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 36 0.061
gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens] 36 0.061
gi|104526627 triadin [Homo sapiens] 36 0.061
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 36 0.079
>gi|4505571 sequestosome 1 isoform 1 [Homo sapiens]
Length = 440
Score = 919 bits (2374), Expect = 0.0
Identities = 440/440 (100%), Positives = 440/440 (100%)
Query: 1 MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRP 60
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRP
Sbjct: 1 MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRP 60
Query: 61 GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRN 120
GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRN
Sbjct: 61 GGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRN 120
Query: 121 MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFS 180
MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFS
Sbjct: 121 MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFS 180
Query: 181 HSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV 240
HSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV
Sbjct: 181 HSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV 240
Query: 241 GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNV 300
GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNV
Sbjct: 241 GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNV 300
Query: 301 EGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPE 360
EGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPE
Sbjct: 301 EGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPE 360
Query: 361 SEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK 420
SEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK
Sbjct: 361 SEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK 420
Query: 421 NYDIGAALDTIQYSKHPPPL 440
NYDIGAALDTIQYSKHPPPL
Sbjct: 421 NYDIGAALDTIQYSKHPPPL 440
>gi|214830451 sequestosome 1 isoform 2 [Homo sapiens]
Length = 356
Score = 751 bits (1940), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 85 MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 144
MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV
Sbjct: 1 MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60
Query: 145 CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 204
CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG
Sbjct: 61 CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120
Query: 205 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 264
NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK
Sbjct: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180
Query: 265 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 324
RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE
Sbjct: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
Query: 325 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 384
QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP
Sbjct: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
Query: 385 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 440
HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Sbjct: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356
>gi|214830438 sequestosome 1 isoform 2 [Homo sapiens]
Length = 356
Score = 751 bits (1940), Expect = 0.0
Identities = 356/356 (100%), Positives = 356/356 (100%)
Query: 85 MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 144
MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV
Sbjct: 1 MAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSV 60
Query: 145 CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 204
CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG
Sbjct: 61 CPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPG 120
Query: 205 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 264
NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK
Sbjct: 121 NWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGK 180
Query: 265 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 324
RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE
Sbjct: 181 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 240
Query: 325 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 384
QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP
Sbjct: 241 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 300
Query: 385 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 440
HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL
Sbjct: 301 HLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL 356
>gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 55.5 bits (132), Expect = 1e-07
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 105 CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 159
C + P ++E P N ++ C+ C +VG RY+CS+CP Y++C CE G
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250
Query: 160 HRGHTKLAFPSPFGHLSEGFSHSRW 184
H L P SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275
>gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 55.5 bits (132), Expect = 1e-07
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 105 CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 159
C + P ++E P N ++ C+ C +VG RY+CS+CP Y++C CE G
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250
Query: 160 HRGHTKLAFPSPFGHLSEGFSHSRW 184
H L P SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275
>gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 55.5 bits (132), Expect = 1e-07
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 5/85 (5%)
Query: 105 CRRDHRPPCAQEA---PRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEG--KGL 159
C + P ++E P N ++ C+ C +VG RY+CS+CP Y++C CE G
Sbjct: 191 CPSEVSMPTSEETLFLPENQFSWHIACNNCQRRIVGVRYQCSLCPSYNICEDCEAGPYGH 250
Query: 160 HRGHTKLAFPSPFGHLSEGFSHSRW 184
H L P SE F HS++
Sbjct: 251 DTNHVLLKLRRPVVGSSEPFCHSKY 275
>gi|30348954 mindbomb homolog 1 [Homo sapiens]
Length = 1006
Score = 48.1 bits (113), Expect = 2e-05
Identities = 22/57 (38%), Positives = 31/57 (54%), Gaps = 2/57 (3%)
Query: 117 APRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVC-EGKGLHRGHTKLAFPSP 171
AP + H +CD C P++G R+KC+ C +YDLC+VC G H H +P
Sbjct: 74 APTGIKHDGTMCDTCRQQPIIGIRWKCAECTNYDLCTVCYHGDKHHLRHRFYRITTP 130
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 47.0 bits (110), Expect = 3e-05
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 13/82 (15%)
Query: 122 VHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVC-EGKGLHRGHTKLAFPSPFGHLSEGF 179
+HP V CDGC P+ G+R+KC C D+D C C + K + HT FG ++E
Sbjct: 2702 IHPGVTCDGCQMFPINGSRFKCRNCDDFDFCETCFKTKKHNTRHT-------FGRINEPG 2754
Query: 180 SHS----RWLRKVKHGHFGWPG 197
+ R +++K H PG
Sbjct: 2755 QSAVFCGRSGKQLKRCHSSQPG 2776
>gi|21264330 mindbomb homolog 2 [Homo sapiens]
Length = 1013
Score = 45.4 bits (106), Expect = 1e-04
Identities = 19/33 (57%), Positives = 23/33 (69%), Gaps = 1/33 (3%)
Query: 123 HPNVICDGCNGPVV-GTRYKCSVCPDYDLCSVC 154
HPN+ICD C + G R+KC VC DYDLC+ C
Sbjct: 144 HPNIICDCCKKHGLRGMRWKCRVCLDYDLCTQC 176
>gi|46852178 potassium channel modulatory factor 1 [Homo sapiens]
Length = 381
Score = 43.5 bits (101), Expect = 4e-04
Identities = 19/37 (51%), Positives = 21/37 (56%), Gaps = 1/37 (2%)
Query: 123 HPNVICDGC-NGPVVGTRYKCSVCPDYDLCSVCEGKG 158
H V CD C G G RYKC +C DYDLC+ C G
Sbjct: 4 HEGVSCDACLKGNFRGRRYKCLICYDYDLCASCYESG 40
>gi|73747881 zinc finger, ZZ type with EF hand domain 1 [Homo sapiens]
Length = 2961
Score = 43.1 bits (100), Expect = 5e-04
Identities = 16/34 (47%), Positives = 21/34 (61%)
Query: 121 MVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVC 154
MV+ CD C G ++G R C+VC D+DLC C
Sbjct: 1825 MVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGC 1858
Score = 37.4 bits (85), Expect = 0.027
Identities = 13/35 (37%), Positives = 21/35 (60%)
Query: 120 NMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVC 154
++++ ++ CDGC+ RY+C C D DLC C
Sbjct: 1775 DLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTC 1809
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 40.4 bits (93), Expect = 0.003
Identities = 48/215 (22%), Positives = 79/215 (36%), Gaps = 20/215 (9%)
Query: 202 PPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEH 261
PP S P+AG A PGP S + P+ P + A+ L E
Sbjct: 1123 PPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSE 1182
Query: 262 GGKRSRL--TPVSPESSSTEEKSSSQPSSCCSDP----------SKPGGNVEGATQSLAE 309
K S P+ P+++ + S P+ +P S P N+E Q
Sbjct: 1183 TSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPR 1242
Query: 310 QMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP 369
+L SE + Q++++ S G + S ++DP +L + S+ S+
Sbjct: 1243 SRSSHSLPSEASSQPQVKTNGISDGKRE----SPLKIDPFE-DLSFNLLAVSKAQLSV-- 1295
Query: 370 SQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSM 404
Q P + LP ++ S+S M +M
Sbjct: 1296 -QTSPVPTPDPKRLIQLPSATQSNVLSSVSCMPTM 1329
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 39.7 bits (91), Expect = 0.005
Identities = 47/197 (23%), Positives = 69/197 (35%), Gaps = 31/197 (15%)
Query: 124 PNVICDGCNGPVVGTRYKCS--------VCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHL 175
P IC NG ++ + +C V P + C VC T + FG
Sbjct: 58 PCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCS-------QTPGGGNTNFGRG 110
Query: 176 SEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTA------------- 222
+G L V G G PG GPPG+ PR R + RPGP
Sbjct: 111 RKGQKGEPGLVPVVTGIRGRPG-PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ 169
Query: 223 ESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSS--TEE 280
A GP PS + +A ++ L + + + G + PV P +
Sbjct: 170 PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQ 229
Query: 281 KSSSQPSSCCSDPSKPG 297
+ + P+ +P PG
Sbjct: 230 QGGAGPTGPPGEPGDPG 246
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 39.7 bits (91), Expect = 0.005
Identities = 54/241 (22%), Positives = 84/241 (34%), Gaps = 50/241 (20%)
Query: 201 GPPGNWSPRPPRAGEARPGP----------------------------TAESASGPSEDP 232
GPP P PPRA RP T+ S+S + P
Sbjct: 271 GPPPP-PPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKP 329
Query: 233 SVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSD 292
+ + GE V A P + ++VE + S + S+ SSS S
Sbjct: 330 AKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDS 389
Query: 293 PSKPGGN-VEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTG 351
+P N +G +S+ E ++ EE E D+ SG + ++ + +P G
Sbjct: 390 DFEPSQNHSQGPLRSMVEDLQS---------EESDEDDSSSGEE------AAGKTNP--G 432
Query: 352 ELQSLQMPESEGPSSLD---PSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSD 408
L +SE +S D PS+E P K + P ++L G D
Sbjct: 433 RDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYD 492
Query: 409 E 409
+
Sbjct: 493 K 493
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 39.7 bits (91), Expect = 0.005
Identities = 25/78 (32%), Positives = 41/78 (52%), Gaps = 5/78 (6%)
Query: 273 PESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCS 332
PES S++ +SSS +D S G ++ ++ S++ + E EG EE+ E +
Sbjct: 376 PESCSSDSESSSYSDHAAND-SDFGSSLSSSSNSVSSEEE----EEEGEEEEEEEEEEGG 430
Query: 333 GGDDDWTHLSSKEVDPST 350
G D + +SS+E D ST
Sbjct: 431 SGASDSSEVSSEEEDSST 448
>gi|71043932 zinc finger, SWIM domain containing 2 [Homo sapiens]
Length = 633
Score = 39.3 bits (90), Expect = 0.007
Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Query: 103 KECRRDHRPPCAQEAPRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVCEGKGLHR 161
+E + + A E R H + C+ C P+ G YKC+ C +Y LC C H
Sbjct: 209 EEFKNSSKLVAAAEKERLDKHLGIPCNNCKQFPIEGKCYKCTECIEYHLCQECFDSCCHL 268
Query: 162 GHT 164
HT
Sbjct: 269 SHT 271
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 38.9 bits (89), Expect = 0.009
Identities = 42/168 (25%), Positives = 62/168 (36%), Gaps = 26/168 (15%)
Query: 265 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALES------ 318
+ R + S SSS+ SSS SS S + EG++ + ++ + S
Sbjct: 2528 KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPK 2587
Query: 319 ----EGRPEE---------QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPS 365
EGRP E S + S + SS S+ S S S
Sbjct: 2588 EAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2647
Query: 366 SLDPSQEGPTGLKEAALYPHLPPEADPRL------IESLSQMLSMGFS 407
S P++ GP L + A P PP + R I+SL S+ +S
Sbjct: 2648 SPSPAKPGPQALPKPA-SPKKPPPGERRSRSPRKPIDSLRDSRSLSYS 2694
Score = 30.8 bits (68), Expect = 2.6
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 6/94 (6%)
Query: 217 RPGPTAESASGPSEDPSVNFL---KNVGESVAAALSPLGIE-VDIDVEHGGKRSRLTPVS 272
RP P+ E +S E P+ L ++ G A +PL E V+ E R R P S
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 273 PESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQS 306
PE S S P S P+K + + +S
Sbjct: 409 PEKLPQSSSSESSPPS--PQPTKVSRHASSSPES 440
>gi|157364926 dystrotelin [Homo sapiens]
Length = 578
Score = 38.9 bits (89), Expect = 0.009
Identities = 21/58 (36%), Positives = 30/58 (51%), Gaps = 4/58 (6%)
Query: 111 PPCAQ-EAPRNMVHPNVICDGCNG-PVVGTRYKCSVCPDYDLCSVCEGKGLH-RGHTK 165
P C + A + HP C C P+ G RY+C C ++D+C +C GLH + H K
Sbjct: 211 PTCHRLSAAERVTHP-ARCTLCRTFPITGLRYRCLKCLNFDICQMCFLSGLHSKSHQK 267
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 38.5 bits (88), Expect = 0.012
Identities = 38/128 (29%), Positives = 48/128 (37%), Gaps = 26/128 (20%)
Query: 195 WPG--WEMGPPGNWSPRPPRAG-------EARPGPTAESASGPSEDPSVNFLKNVGESVA 245
W G W PG W PRP R G +PGP E + P + GE VA
Sbjct: 369 WEGYPWGFSEPGVWGPRPCRVGCREVFGRGGQPGPKYEIWTNPLH-------ASQGERVA 421
Query: 246 AALSPLGIEVDIDVE-------HGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGG 298
A G+ + G +R SP SS+ + S SSCC P P
Sbjct: 422 AR-KRWGLAQHVRCSGLWGHGTAGRERCSQDSASPASSTGLPEGSEPESSCC--PRTPED 478
Query: 299 NVEGATQS 306
V+ A+ S
Sbjct: 479 GVDSASPS 486
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 37.4 bits (85), Expect = 0.027
Identities = 35/152 (23%), Positives = 58/152 (38%), Gaps = 14/152 (9%)
Query: 185 LRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNV---- 240
L +V+ FG G E+ +P PP A P P + P +P L V
Sbjct: 957 LEEVEDLEFGTAGGEVE---EGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPG 1013
Query: 241 -----GESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSK 295
G A L+P + +VE G+ P P EE+ S+ P+ +
Sbjct: 1014 TEEERGADTAPTLAPEALPSQGEVEREGESPAAGP--PPQELVEEEPSAPPTLLEEETED 1071
Query: 296 PGGNVEGATQSLAEQMRKIALESEGRPEEQME 327
V+ ++ AE+ + E+E E++ +
Sbjct: 1072 GSDKVQPPPETPAEEEMETETEAEALQEKEQD 1103
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 37.4 bits (85), Expect = 0.027
Identities = 51/222 (22%), Positives = 76/222 (34%), Gaps = 27/222 (12%)
Query: 196 PGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEV 255
PG GN P+ P +A ES S S S +++ S G E
Sbjct: 2531 PGLTFEDSGN--PKSPDKAQAEQDGAEESESSSSSSSG-------SSSSSSSSSSSGSET 2581
Query: 256 DIDVEH----------GGKRSRLTP---VSPESSSTEEKSSSQPSSCCSDPSKPGGNVEG 302
+ + E GG+ SP SSS+ SSS SS S S +
Sbjct: 2582 EGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
Query: 303 ATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEV--DPSTGELQSLQMP- 359
++ S + + S S + S D+D + S E P+ G +P
Sbjct: 2642 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPT 2701
Query: 360 -ESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQ 400
++ PS P G K A P PP + ++ +Q
Sbjct: 2702 KATKQAGKARPSAHSP-GKKTPAPQPQAPPPQPTQPLQPKAQ 2742
>gi|10863903 thyroid hormone receptor interactor 12 [Homo sapiens]
Length = 1992
Score = 37.0 bits (84), Expect = 0.036
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 10/111 (9%)
Query: 271 VSPESSSTEEKSSSQPSSCCSDPSKPGGNV-EGATQSLAEQMRKIALESEGRPEEQMESD 329
++ SS+ SSS + S PG V +G Q+ A + R + S R + E
Sbjct: 193 ITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSPSPRRSSREKEQS 252
Query: 330 NCSGGDD-DWTHLSSKEVD-PSTGELQSLQMPESEGPSSLDPSQEGPTGLK 378
G DW S +V P T L +P G S + S+ GP+GL+
Sbjct: 253 KTGGSSKFDWAARFSPKVSLPKT----KLSLP---GSSKSETSKPGPSGLQ 296
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 36.6 bits (83), Expect = 0.047
Identities = 58/199 (29%), Positives = 82/199 (41%), Gaps = 47/199 (23%)
Query: 215 EARPGPT-----AESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLT 269
EA P P A++ G SED + L++VG+S A P + V GK+ L
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAA----PTFMISPETVTGTGKKCSLP 638
Query: 270 PVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESD 329
+ E S E+ +P C S PS+ L+ + IA EGRP
Sbjct: 639 --AEEDSVLEKLGERKP--CNSQPSE-----------LSSETSGIARPEEGRPV------ 677
Query: 330 NCSGGDDDWTHLSSKEVDPS----TGELQSLQMPESE------GPSSLDPSQEGPTGL-- 377
SG +D T +KE+ PS T L + Q ++ P+SL P Q PT +
Sbjct: 678 -VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL-PKQPAPTTIGG 735
Query: 378 ---KEAALYPHLPPEADPR 393
K +L L P A P+
Sbjct: 736 LNKKPMSLASGLVPAAPPK 754
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
sapiens]
Length = 1152
Score = 36.6 bits (83), Expect = 0.047
Identities = 58/199 (29%), Positives = 82/199 (41%), Gaps = 47/199 (23%)
Query: 215 EARPGPT-----AESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLT 269
EA P P A++ G SED + L++VG+S A P + V GK+ L
Sbjct: 583 EATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAA----PTFMISPETVTGTGKKCSLP 638
Query: 270 PVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESD 329
+ E S E+ +P C S PS+ L+ + IA EGRP
Sbjct: 639 --AEEDSVLEKLGERKP--CNSQPSE-----------LSSETSGIARPEEGRPV------ 677
Query: 330 NCSGGDDDWTHLSSKEVDPS----TGELQSLQMPESE------GPSSLDPSQEGPTGL-- 377
SG +D T +KE+ PS T L + Q ++ P+SL P Q PT +
Sbjct: 678 -VSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL-PKQPAPTTIGG 735
Query: 378 ---KEAALYPHLPPEADPR 393
K +L L P A P+
Sbjct: 736 LNKKPMSLASGLVPAAPPK 754
>gi|42718005 dystrobrevin alpha isoform 1 [Homo sapiens]
Length = 743
Score = 36.6 bits (83), Expect = 0.047
Identities = 73/333 (21%), Positives = 121/333 (36%), Gaps = 44/333 (13%)
Query: 120 NMVHPNVICDGCNGP-VVGTRYKCSVCPDYDLCSVCEGKG--------LHRGHTKLAFPS 170
N+ HP V C C+ ++G RY+C C +Y LC C +G H+ ++ S
Sbjct: 236 NVFHP-VECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKS 294
Query: 171 PFGHLSEGFSHSRWLRKVKHG-HFGWPGWEMGP------PGNWSPRPPRA--------GE 215
P L+ S S + H +P P W PRP +
Sbjct: 295 PAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSV 354
Query: 216 ARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPES 275
G + S P +D V K + + A L GI+ ++V RL
Sbjct: 355 PSSGSPFITRSSPPKDSEVEQNKLLARAAPAFLKGKGIQYSLNV-----ADRLADEHVLI 409
Query: 276 SSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALE-SEGRPEEQMESDNCS-- 332
+ P SC + S ++ + +A ++A E S +P +Q + + S
Sbjct: 410 GLYVNMLRNNP-SCMLESS---NRLDEEHRLIARYAARLAAESSSSQPPQQRSAPDISFT 465
Query: 333 -GGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDP----SQEGPTGLKEAALYPHLP 387
+ L ++ + + LQ +Q E + P +Q+ PT L E L
Sbjct: 466 IDANKQQRQLIAELENKNREILQEIQRLRLEHEQASQPTPEKAQQNPTLLAELRLLRQRK 525
Query: 388 PEADPRLIESLSQMLSMGFSDEGGWLTRLLQTK 420
E + R+ + EG L +LL+T+
Sbjct: 526 DELEQRMSALQESRRELMVQLEG--LMKLLKTQ 556
>gi|55741849 WD repeat domain 22 [Homo sapiens]
Length = 942
Score = 36.2 bits (82), Expect = 0.061
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 18/164 (10%)
Query: 218 PGPTAESASGPSEDPSVNFLKNVGESVAAALSPLG------IEVDIDVEHGGKRSRLTPV 271
P PT E A+ S ++ L+ + ALS EV++D + L P
Sbjct: 499 PTPTCEDAA--SRQQRLSALRRYQDKRLLALSNESDSEENVCEVELDTD-------LFP- 548
Query: 272 SPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNC 331
P S S E++SSS SS S+ + +T R+ E +P ++ N
Sbjct: 549 RPRSPSPEDESSSSSSSSSSEDEEELNERRASTWQRNAMRRRQKTTREDKPSAPIKPTNT 608
Query: 332 SGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPT 375
G+D++ + K D S+ S + S + PS+ PT
Sbjct: 609 YIGEDNYDYPQIKVDDLSSSPTSSPE--RSTSTLEIQPSRASPT 650
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 36.2 bits (82), Expect = 0.061
Identities = 45/206 (21%), Positives = 76/206 (36%), Gaps = 20/206 (9%)
Query: 211 PRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRL-- 268
P+AG A PGP S + P+ P + A+ L E K S
Sbjct: 1218 PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLP 1277
Query: 269 TPVSPESSSTEEKSSSQPSSCCSDP----------SKPGGNVEGATQSLAEQMRKIALES 318
P+ P+++ + S P+ +P S P N+E Q +L S
Sbjct: 1278 EPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPS 1337
Query: 319 EGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLK 378
E + Q++++ S G + S ++DP +L + S+ S+ Q P
Sbjct: 1338 EASSQPQVKTNGISDGKRE----SPLKIDPFE-DLSFNLLAVSKAQLSV---QTSPVPTP 1389
Query: 379 EAALYPHLPPEADPRLIESLSQMLSM 404
+ LP ++ S+S M +M
Sbjct: 1390 DPKRLIQLPSATQSNVLSSVSCMPTM 1415
>gi|42718003 dystrobrevin alpha isoform 3 [Homo sapiens]
Length = 570
Score = 36.2 bits (82), Expect = 0.061
Identities = 40/164 (24%), Positives = 61/164 (37%), Gaps = 25/164 (15%)
Query: 120 NMVHPNVICDGCNGP-VVGTRYKCSVCPDYDLCSVCEGKG--------LHRGHTKLAFPS 170
N+ HP V C C+ ++G RY+C C +Y LC C +G H+ ++ S
Sbjct: 236 NVFHP-VECSYCHSESMMGFRYRCQQCHNYQLCQDCFWRGHAGGSHSNQHQMKEYTSWKS 294
Query: 171 PFGHLSEGFSHSRWLRKVKHG-HFGWPGWEMGP------PGNWSPRPPRA--------GE 215
P L+ S S + H +P P W PRP +
Sbjct: 295 PAKKLTNALSKSLSCASSREPLHPMFPDQPEKPLNLAHIVDTWPPRPVTSMNDTLFSHSV 354
Query: 216 ARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDV 259
G + S P +D V K + + A L GI+ ++V
Sbjct: 355 PSSGSPFITRSSPPKDSEVEQNKLLARAAPAFLKGKGIQYSLNV 398
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 36.2 bits (82), Expect = 0.061
Identities = 36/194 (18%), Positives = 73/194 (37%), Gaps = 12/194 (6%)
Query: 210 PPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEH-----GGK 264
P +A E + G +A ++ + A P G + + +H K
Sbjct: 352 PGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPK 411
Query: 265 RSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEE 324
+ P + + E++ + + + PG E T+++ +++RK E G+
Sbjct: 412 KEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRK---EKSGKTSS 468
Query: 325 QMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYP 384
++ G ++ S KE +P T + + + S+ + P G KE P
Sbjct: 469 ILKDKEPIKGKEEKVPASLKEKEPETKKDEKM----SKAGKEVKPKPPQLQGKKEEKPEP 524
Query: 385 HLPPEADPRLIESL 398
+ EA P + E +
Sbjct: 525 QIKKEAKPAISEKV 538
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 35.8 bits (81), Expect = 0.079
Identities = 44/174 (25%), Positives = 63/174 (36%), Gaps = 17/174 (9%)
Query: 228 PSEDPSVNF-------LKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEE 280
P+ DP N LK + + AAA+ P+ +V H R P P +
Sbjct: 947 PTGDPRANASPQKPLDLKQLKQR-AAAIPPIVTKV-----HEPPREDAAPTKPAPPAPPP 1000
Query: 281 KSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTH 340
+ QP S P +PG + G ++S A K A + P E+ G WT
Sbjct: 1001 PQNLQPES--DAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTS 1058
Query: 341 LSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAA--LYPHLPPEADP 392
V P S P+ S P P GL + A + P P ++P
Sbjct: 1059 GLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTARPVLPRPPTISNP 1112
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,701,593
Number of Sequences: 37866
Number of extensions: 1287202
Number of successful extensions: 6168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 272
Number of HSP's that attempted gapping in prelim test: 5708
Number of HSP's gapped (non-prelim): 624
length of query: 440
length of database: 18,247,518
effective HSP length: 105
effective length of query: 335
effective length of database: 14,271,588
effective search space: 4780981980
effective search space used: 4780981980
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.