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Search of human proteins with 12711674
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
(470 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso... 937 0.0
gi|18375528 UPF3 regulator of nonsense transcripts homolog B iso... 928 0.0
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso... 398 e-111
gi|18375525 UPF3 regulator of nonsense transcripts homolog A iso... 332 4e-91
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 103 3e-22
gi|148746195 trichohyalin [Homo sapiens] 99 8e-21
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 98 1e-20
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 97 3e-20
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 96 5e-20
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 96 5e-20
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 96 5e-20
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 94 2e-19
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 93 5e-19
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 93 6e-19
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 92 1e-18
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 91 3e-18
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 91 3e-18
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 91 3e-18
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 91 3e-18
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 89 9e-18
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 89 1e-17
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 89 1e-17
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 88 2e-17
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 86 9e-17
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 83 6e-16
gi|221219020 NYD-SP11 protein [Homo sapiens] 82 1e-15
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 82 1e-15
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 81 2e-15
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 81 2e-15
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 81 2e-15
>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
isoform 2 [Homo sapiens]
Length = 470
Score = 937 bits (2423), Expect = 0.0
Identities = 470/470 (100%), Positives = 470/470 (100%)
Query: 1 MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP 60
MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP
Sbjct: 1 MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP 60
Query: 61 TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL 120
TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL
Sbjct: 61 TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL 120
Query: 121 DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET 180
DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET
Sbjct: 121 DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET 180
Query: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE
Sbjct: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
Query: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER 300
KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER
Sbjct: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER 300
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEER 360
ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEER
Sbjct: 301 ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEER 360
Query: 361 RRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRN 420
RRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRN
Sbjct: 361 RRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRN 420
Query: 421 KDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
KDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE
Sbjct: 421 KDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
>gi|18375528 UPF3 regulator of nonsense transcripts homolog B
isoform 1 [Homo sapiens]
Length = 483
Score = 928 bits (2399), Expect = 0.0
Identities = 470/483 (97%), Positives = 470/483 (97%), Gaps = 13/483 (2%)
Query: 1 MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP 60
MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP
Sbjct: 1 MKEEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPP 60
Query: 61 TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL 120
TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL
Sbjct: 61 TLTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFL 120
Query: 121 DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET 180
DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET
Sbjct: 121 DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPET 180
Query: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE
Sbjct: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
Query: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIK-------------LLKKPEKGDEKELDKREK 287
KRKRKDIEKLKKIDRIPERDKLKDEPKIK LLKKPEKGDEKELDKREK
Sbjct: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREK 300
Query: 288 AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL 347
AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL
Sbjct: 301 AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL 360
Query: 348 RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTE 407
RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTE
Sbjct: 361 RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTE 420
Query: 408 KKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEG 467
KKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEG
Sbjct: 421 KKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEG 480
Query: 468 GEE 470
GEE
Sbjct: 481 GEE 483
>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3p [Homo sapiens]
Length = 476
Score = 398 bits (1023), Expect = e-111
Identities = 214/451 (47%), Positives = 302/451 (66%), Gaps = 40/451 (8%)
Query: 3 EEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPPTL 62
E + HR +++ P ++G GGG G+ ++ EK+ ALSKVVIRRLPP L
Sbjct: 30 EVQFHRDSQQQEAETPPTSSSGCGGGA------GKPRE----EKRTALSKVVIRRLPPGL 79
Query: 63 TKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDN 122
TKEQL+E L+P+P HDYFEFF+ D SLYPH+Y+RAYINF+N +DI+LFRDRFDGY+FLD+
Sbjct: 80 TKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSRAYINFRNPDDILLFRDRFDGYIFLDS 139
Query: 123 KGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLL 182
KG EYPA+VEFAPFQK AKKK +K+D K G+I+DDPEY+KFLE+Y + EK ++ PETLL
Sbjct: 140 KGLEYPAVVEFAPFQKIAKKKLRKKDAKTGSIEDDPEYKKFLETYCVEEEKTSANPETLL 199
Query: 183 EEIEAKNRELIAKKTTPLLSFLKN----KQRMREEKREERRRREIERKRQREEERRKWKE 238
E+EAK RELIA++TTPLL ++KN KQR+REEKREERRRRE+E+KR REEE+R+ +E
Sbjct: 200 GEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRRE 259
Query: 239 EEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK-REKAKKLDKENLS 297
EE+ K+K+ +K KKI + E +IKLLKKPEKG+E +K +E+ +++D
Sbjct: 260 EERCKKKETDKQKKI--------AEKEVRIKLLKKPEKGEEPTTEKPKERGEEIDTGGGK 311
Query: 298 DERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQE 357
E + + + + L++ P++ S + R+ ER QE +E E +
Sbjct: 312 QESCAPGAVVKARPMEGSLEE-----PQETSHSGSDKEHRDVERSQE---QESEAQRYHV 363
Query: 358 EERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKK--------AESTESIGSSEKTEKK 409
++ RR + +E E+ +R E+E + K +D+GKK E+ E +G +++ +
Sbjct: 364 DDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPGEAMERLGRAQRCD-D 422
Query: 410 EEVVKRDRIRNKDRPAMQLYQPGARSRNRLC 440
+++R+ NKDRPA+QLY PGAR R R C
Sbjct: 423 SPAPRKERLANKDRPALQLYDPGARFRAREC 453
>gi|18375525 UPF3 regulator of nonsense transcripts homolog A
isoform hUpf3pdelta [Homo sapiens]
Length = 443
Score = 332 bits (851), Expect = 4e-91
Identities = 191/451 (42%), Positives = 274/451 (60%), Gaps = 73/451 (16%)
Query: 3 EEKEHRPKEKRVTLLTPAGATGSGGGTSGDSSKGEDKQDRNKEKKEALSKVVIRRLPPTL 62
E + HR +++ P ++G GGG G+ ++ EK+ ALSKVVIRRLPP L
Sbjct: 30 EVQFHRDSQQQEAETPPTSSSGCGGGA------GKPRE----EKRTALSKVVIRRLPPGL 79
Query: 63 TKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDN 122
TKEQL+E L+P+P HDYFEFF+ D SLYPH+Y+RAYINF+N +DI+LFRDRFDGY+FLD+
Sbjct: 80 TKEQLEEQLRPLPAHDYFEFFAADLSLYPHLYSRAYINFRNPDDILLFRDRFDGYIFLDS 139
Query: 123 KGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLL 182
K DPEY+KFLE+Y + EK ++ PETLL
Sbjct: 140 K---------------------------------DPEYKKFLETYCVEEEKTSANPETLL 166
Query: 183 EEIEAKNRELIAKKTTPLLSFLKN----KQRMREEKREERRRREIERKRQREEERRKWKE 238
E+EAK RELIA++TTPLL ++KN KQR+REEKREERRRRE+E+KR REEE+R+ +E
Sbjct: 167 GEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREEKREERRRRELEKKRLREEEKRRRRE 226
Query: 239 EEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK-REKAKKLDKENLS 297
EE+ K+K+ +K KKI + E +IKLLKKPEKG+E +K +E+ +++D
Sbjct: 227 EERCKKKETDKQKKI--------AEKEVRIKLLKKPEKGEEPTTEKPKERGEEIDTGGGK 278
Query: 298 DERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQE 357
E + + + + L++ P++ S + R+ ER QE +E E +
Sbjct: 279 QESCAPGAVVKARPMEGSLEE-----PQETSHSGSDKEHRDVERSQE---QESEAQRYHV 330
Query: 358 EERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKK--------AESTESIGSSEKTEKK 409
++ RR + +E E+ +R E+E + K +D+GKK E+ E +G +++ +
Sbjct: 331 DDGRRHRAHHEPERLSRRSEDEQRWGKGPGQDRGKKGSQDSGAPGEAMERLGRAQRCD-D 389
Query: 410 EEVVKRDRIRNKDRPAMQLYQPGARSRNRLC 440
+++R+ NKDRPA+QLY PGAR R R C
Sbjct: 390 SPAPRKERLANKDRPALQLYDPGARFRAREC 420
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 103 bits (258), Expect = 3e-22
Identities = 75/273 (27%), Positives = 138/273 (50%), Gaps = 11/273 (4%)
Query: 205 KNKQRMREEKREERRRREIERKRQ-----REEERRKWKEEEKRKRKDIEKLKKIDRIPER 259
+ K+R RE+ R+ERR RE +R+++ R ER + +E E+ + E+ ++ DR +R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 260 DKLKDEPKIKLLKKPEKGDEKELDK-REKAKKLDKENLSDERASGQSC-TLPKRSDSELK 317
+ + + K ++ E+ E+E ++ +E+ ++ D++ D R + T KR +
Sbjct: 235 QRKTEREREKQAER-ERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTER 293
Query: 318 DEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKE 377
D + +R + RERER +R++ER RERER +++E ER R+KER K K ++ E
Sbjct: 294 DRETERKRERQRERERERERNRKRERERE-RERERERQRETERDREKERERKRK--RQTE 350
Query: 378 EEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRN 437
+ ++ + T R+ ++AE + E +R+R R++DR + Q
Sbjct: 351 MDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDG 410
Query: 438 RLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
+ + D +ER +E G K+ G E
Sbjct: 411 QRETEKQREREKDRESERGRERGREREKQKGRE 443
Score = 100 bits (248), Expect = 4e-21
Identities = 75/270 (27%), Positives = 142/270 (52%), Gaps = 22/270 (8%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
K++ R R+ RE +R RE ER+RQ + ER + +E+E+ ++K+ E+ + + RD+ D
Sbjct: 85 KDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTD 144
Query: 265 EPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRP 324
+ + ++ + + + RE+ ++ ++ N ER ++ +R + E + EK +
Sbjct: 145 GQRERERQRDAEKERERQTDRERQRQTER-NRQKEREREKN--RQERRERERQREKENKT 201
Query: 325 ED---ESGRDYREREREYERDQER---ILRERERLKRQEEERRRQ--KERYEKEKTFKRK 376
ED E GR+ RERERE E + ER RER+R ++ E ER +Q +ER + +T + K
Sbjct: 202 EDRHSERGRE-RERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDK 260
Query: 377 EEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSR 436
E E ++++D RD+ +K ++ ++ +++ +R R R ++R R R
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER-------ERER 313
Query: 437 NRLCPPDDSTKSGDSAAERKQESGISHRKE 466
NR + + + ER++E+ KE
Sbjct: 314 NR---KRERERERERERERQRETERDREKE 340
Score = 98.2 bits (243), Expect = 1e-20
Identities = 72/279 (25%), Positives = 142/279 (50%), Gaps = 25/279 (8%)
Query: 205 KNKQRMREEKREER-----------RRREIERKRQREEERRKWKEEEKRKRKDIEKLKKI 253
+N+Q+ RE +RE+R RRRE +R R+R+ R + ++ EK + + ++ +
Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDR 115
Query: 254 DRIPERDKLKDEPKIKLLKKPEKGDEKELD-KREKAKKLDKENLSDERASGQSCTLPKRS 312
R ER++ K+ + + ++ E+G +++ D +RE+ ++ D E + + T +R
Sbjct: 116 QREKERNRQKERER-ETEREGERGRDRQTDGQRERERQRDAEKERERQ------TDRERQ 168
Query: 313 DSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKT 372
++ + +R +++ ++ RERER+ E++ + R ER + +E ER + E K +T
Sbjct: 169 RQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPG 432
+ ++ + K E R++ K+AE E E KE +RDR R++DR + +
Sbjct: 229 DRERDRQRKTE----REREKQAE-RERASERETERDKERERERDRDRDRDRRQKERERQT 283
Query: 433 ARSRNRLCPPDDST-KSGDSAAERKQESGISHRKEGGEE 470
R R R D T + + ER++E + ++E E
Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Score = 97.8 bits (242), Expect = 2e-20
Identities = 72/283 (25%), Positives = 145/283 (51%), Gaps = 28/283 (9%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
+++QR +E R++ R RE ER+ +R +R+ + E+ +++D EK ++ ER + +
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 265 EPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPK-- 322
+ +K + ++ ++RE+ ++ +KEN +++R S + + ++E + E+ +
Sbjct: 173 RNR----QKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 323 -RPEDESGRDYRERE----------REYERDQERIL---RERERLKRQEEERRRQKERYE 368
R D + RERE RE ERD+ER R+R+R +RQ +ER RQ +R
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ-KERERQTDRKR 287
Query: 369 KEKTFKRKEEEMKKEKDTLRDKGK-KAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQ 427
+ +T + +E E K+E+ R++ + + E E+ +++ +RDR + ++R +
Sbjct: 288 QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 428 LYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
+ R RNR + + G AER++E ++ E
Sbjct: 348 QTEMD-RERNR-----QTGREGRRQAERERERERERDRQSARE 384
Score = 97.4 bits (241), Expect = 2e-20
Identities = 68/279 (24%), Positives = 144/279 (51%), Gaps = 13/279 (4%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKI-DRIPERDKLK 263
++ ++ RE + + R+R+ ER RQ+E ER K ++E + + + EK K DR ER + +
Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212
Query: 264 D-EPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPK 322
+ E + + + ++ ++E D++ K ++ ++ ERAS + K + E ++ +
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272
Query: 323 --RPEDESGRDYREREREYERDQE---RILRERERLKRQEEERRRQKERYEKEKTFKRKE 377
R ++ + R+R+R ERD+E + R+RER + +E R+R++ER + + +++E
Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRE 332
Query: 378 EEMKKEKDTLRDKGKKAE-STESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSR 436
E +EK+ R + ++ E E + + +++ +R+R R +DR + + + R R
Sbjct: 333 TERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392
Query: 437 NRLCPPD-----DSTKSGDSAAERKQESGISHRKEGGEE 470
+R + + + G E+++E E G E
Sbjct: 393 DRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRE 431
Score = 96.7 bits (239), Expect = 4e-20
Identities = 81/315 (25%), Positives = 149/315 (47%), Gaps = 43/315 (13%)
Query: 169 TDNEKMTSTPETLLEEIEAKN-----RELIAKKTTPLLSFLKNKQRMREEKREERRRREI 223
TD E+ T +E E + RE ++ + ++ +R RE +RE E
Sbjct: 163 TDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETET 222
Query: 224 ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELD 283
ERKRQ + ER + ++ E+ + K E+ + +R ERDK ++ E+ +++ D
Sbjct: 223 ERKRQTDRERDRQRKTEREREKQAERERASERETERDKERER---------ERDRDRDRD 273
Query: 284 KREKAKKLDKENLSDERASGQSCTLPKRS---DSELKDEKPKRPEDESGRDY-REREREY 339
+R+K ++ + R T KR + E + E+ ++ E E R+ RER+RE
Sbjct: 274 RRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRET 333
Query: 340 ERDQERILRERERLK----------------RQEEERRRQKERYEKEKTFKRKEEEMKKE 383
ERD+E+ RER+R + R++ ER R++ER E+++ R+ EE +++
Sbjct: 334 ERDREKE-RERKRKRQTEMDRERNRQTGREGRRQAERERERER-ERDRQSAREREERERD 391
Query: 384 KDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPD 443
+D R K ++ ++ + +TEK+ E R KDR + + + G +
Sbjct: 392 RDRDRQKERERQTEKDRDGQRETEKQRE-------REKDRESERGRERGREREKQKGRER 444
Query: 444 DSTKSGDSAAERKQE 458
D + D A R+++
Sbjct: 445 DRERQTDRQAGRQRK 459
Score = 92.0 bits (227), Expect = 1e-18
Identities = 74/253 (29%), Positives = 128/253 (50%), Gaps = 17/253 (6%)
Query: 205 KNKQRMREEKRE---ERRR---REIERKRQREEERRKWKEEEKR-KRKDIEKLKKIDRIP 257
+++QR E +RE ER R RE ER ++RE ER + ++ ++R K ++ + +K R
Sbjct: 232 RDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRT 291
Query: 258 ERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELK 317
ERD+ + + + ++ + + +RE+ ++ ++E + + KR
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEM 351
Query: 318 DEKPKRPEDESGRDYREREREYERDQER-ILRERERLKRQEEERRRQKERYEKEKTFKRK 376
D + R GR ERERE ER+++R RERE +R + +R RQKER + +T K +
Sbjct: 352 DRERNRQTGREGRRQAERERERERERDRQSAREREERER-DRDRDRQKER--ERQTEKDR 408
Query: 377 EEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSR 436
+ + + EK R+K +++E G + +K E RDR R DR Q + RS
Sbjct: 409 DGQRETEKQREREKDRESERGRERGREREKQKGRE---RDRERQTDR---QAGRQRKRST 462
Query: 437 NRLCPPDDSTKSG 449
+ PP + +SG
Sbjct: 463 LYVNPPPRTARSG 475
Score = 55.8 bits (133), Expect = 8e-08
Identities = 37/146 (25%), Positives = 72/146 (49%), Gaps = 12/146 (8%)
Query: 325 EDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEK 384
+D G D RER R+ ER++ R R+ ER ++ ERRR+K+R+ K + ++ + +KE+
Sbjct: 47 KDADGDD-RERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105
Query: 385 DTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDD 444
+ D+ + + + ++ E++ E R+ R +DR G R R R D
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETE---REGERGRDRQT-----DGQRERER---QRD 154
Query: 445 STKSGDSAAERKQESGISHRKEGGEE 470
+ K + +R+++ ++ E
Sbjct: 155 AEKERERQTDRERQRQTERNRQKERE 180
Score = 51.2 bits (121), Expect = 2e-06
Identities = 41/181 (22%), Positives = 84/181 (46%), Gaps = 3/181 (1%)
Query: 280 KELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREY 339
+E +R + K+ D+R + +R + + + R + R R+R+
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDR 93
Query: 340 ERDQERIL-RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAE-ST 397
R+++R +ERER +E +R+R+KER +++ + E E ++ +D D ++ E
Sbjct: 94 HRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153
Query: 398 ESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQ 457
++ E+ +E + +R R K+R + Q R R R ++ T+ S R++
Sbjct: 154 DAEKERERQTDRERQRQTERNRQKEREREKNRQE-RRERERQREKENKTEDRHSERGRER 212
Query: 458 E 458
E
Sbjct: 213 E 213
Score = 37.0 bits (84), Expect = 0.039
Identities = 32/123 (26%), Positives = 54/123 (43%), Gaps = 4/123 (3%)
Query: 350 RERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKK 409
R R QE RRR + K+ +E +KE++ R+K + T+ E+ +K
Sbjct: 28 RRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDR--KRERRREK 85
Query: 410 EEVVKRDRIRNKDRP-AMQLYQPGARSRNRLCPPD-DSTKSGDSAAERKQESGISHRKEG 467
+ KRDR R + R + + R R+R + + K + ER+ E G + +G
Sbjct: 86 DRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDG 145
Query: 468 GEE 470
E
Sbjct: 146 QRE 148
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 99.0 bits (245), Expect = 8e-21
Identities = 77/280 (27%), Positives = 148/280 (52%), Gaps = 29/280 (10%)
Query: 204 LKNKQRMREE---KREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERD 260
L+ +Q++R E +RE++ RRE + +R++EEER + K E++R+ +R
Sbjct: 401 LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE-------------QRL 447
Query: 261 KLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEK 320
K + E + LK+ E+ + E ++R++ K D+E + R +R + + + E+
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEE--ERRERWLKLEEEERREQQERREQ 505
Query: 321 PKRPEDESGRDYR-EREREYERDQERILRERERLKRQEEERRRQKERYEKEKTF--KRKE 377
R E E R+ R +R+ E ER Q+R LR ++L+R++EERR Q + E+EK +R+E
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQR-LRSEQQLRREQEERREQLLKREEEKRLEQERRE 564
Query: 378 EEMKKEKDTLRDK--GKKAESTESIGSSEKTEKKEEVVKR---DRIRNKDRPAMQL--YQ 430
+ +K+E++ RD+ ++ E + E+ E+ E+ +KR +R+ ++R +L +
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREE 624
Query: 431 PGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
P R +L ++ + R+Q+ R + EE
Sbjct: 625 PEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEE 664
Score = 96.7 bits (239), Expect = 4e-20
Identities = 70/296 (23%), Positives = 159/296 (53%), Gaps = 23/296 (7%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+++ ++R +V +++ E+RK + EK+ E++ + +L + L
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQEL 286
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERD 260
++R EE++++R RRE + +R++EEERR+ ++EE+R++++ + ++ R +
Sbjct: 287 -----RRERQEEEQQQQRLRREQQLRRKQEEERRE-QQEERREQQERREQQEERREQQLR 340
Query: 261 KLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEK 320
+ ++E + + L++ E+E ++RE+ + ++E E+ + L R + +L+ E+
Sbjct: 341 REQEERREQQLRR-----EQEEERREQQLRREQEEERREQQLRREQQL--RREQQLRREQ 393
Query: 321 PKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEM 380
R E + R+ + R + R ++++ RE++ + QEEER QK E R+E+ +
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQE------RREQRL 447
Query: 381 KKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSR 436
K+E++ RD K+ E TE + E++++ +KRD+ + ++L + R +
Sbjct: 448 KREQEERRDWLKREEETE----RHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Score = 94.0 bits (232), Expect = 3e-19
Identities = 77/312 (24%), Positives = 160/312 (51%), Gaps = 43/312 (13%)
Query: 182 LEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK 241
LEE + R + K L L+ +Q++ +E+ EE +R E E KR+R+E+ R+++EEE+
Sbjct: 878 LEEERKRRRHTLYAKPA-LQEQLRKEQQLLQEEEEELQREERE-KRRRQEQERQYREEEQ 935
Query: 242 RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKEL----DKREKAKKLDKENLS 297
++++ + L++ ER+K + + + + +K +K +KE ++ EK ++ ++E
Sbjct: 936 LQQEEEQLLRE-----EREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKY 990
Query: 298 DERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRE-------- 349
E L + + L++E+ KR E R YR+++ E ++++E++LRE
Sbjct: 991 REEEE-----LQQEEEQLLREEREKRRRQEWERQYRKKD-ELQQEEEQLLREEREKRRLQ 1044
Query: 350 -RERLKRQEEERRRQKE-----------RYEKEKTFKRKEEEMKKEKDTLR---DKGKKA 394
RER R+EEE ++++E R E E+ ++++EE ++E+ LR +K ++
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQ 1104
Query: 395 ESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAE 454
E E+ +++EE + R+ + R ++ R + ++ +
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRRRQELERQY---REEEEVQQEEEQLLREEPEKR 1161
Query: 455 RKQESGISHRKE 466
R+QE +R+E
Sbjct: 1162 RRQELERQYREE 1173
Score = 92.8 bits (229), Expect = 6e-19
Identities = 82/318 (25%), Positives = 158/318 (49%), Gaps = 46/318 (14%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLE---SYATDNEKMTSTPETLLEEIEAKNRELI 193
++ +K K + + + ++PE R+ E Y + E + L EE E + R+
Sbjct: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEW 1016
Query: 194 AKKTTPLLSFLKNKQRMREEKREERRRREIERKR------QREEERRKWKEEEKRKRKDI 247
++ + ++++ E+RE+RR +E ER+ Q+EEE+ +E E R+R+++
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076
Query: 248 EKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCT 307
E+ + + ++L+ E + L ++PEK +E RE+ + ++E
Sbjct: 1077 ERQYR-----KEEELQQEEEQLLREEPEKRRRQE---RERQCREEEE------------- 1115
Query: 308 LPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRER-ERLKRQEEERRRQKE- 365
L + + L++E+ KR E R YRE E E ++++E++LRE E+ +RQE ER+ ++E
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQYREEE-EVQQEEEQLLREEPEKRRRQELERQYREEE 1174
Query: 366 ----------RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTE---KKEEV 412
R E+EK + +E + ++E++ R K K+ E S K + +KE
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENA 1234
Query: 413 VKRDRIRNKDRPAMQLYQ 430
V+ +++ K R Q Q
Sbjct: 1235 VRDNKVYCKGRENEQFRQ 1252
Score = 92.4 bits (228), Expect = 8e-19
Identities = 62/236 (26%), Positives = 136/236 (57%), Gaps = 22/236 (9%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDI---EKLKKIDRIPERDK 261
+ +Q++R E+ EERR +++ R++Q E++ +E++ R+ + + ++L++ ++ +
Sbjct: 359 RREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 418
Query: 262 LKDEPKIKLLKKPEKGDEK-ELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEK 320
L+ E +++ ++ E+ ++K E ++RE+ K ++E D + +R + E + ++
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET---ERHEQERRKQQ 475
Query: 321 PKRPEDESGRDY------REREREYERDQERILRERE-----RLKRQEEERRRQKERYEK 369
KR ++E R+ ER + ER ++++ RE+E RLKRQEEE R Q +R
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQ-QRLRS 534
Query: 370 EKTFKRKEEEMKKEKDTLRDKGKKAES--TESIGSSEKTEKKEEVVKRDRIRNKDR 423
E+ +R++EE ++E+ R++ K+ E E E+ E++++++KR+ R + R
Sbjct: 535 EQQLRREQEE-RREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Score = 92.4 bits (228), Expect = 8e-19
Identities = 71/334 (21%), Positives = 177/334 (52%), Gaps = 24/334 (7%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
++K ++R++++ +++ +R+ E + ++ T + EE + R+ ++ + PL
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQE----EEQRRDFTWQWQAEEKSERGRQRLSARP-PL 790
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKR-----KRKDIEKLKKIDR 255
+ ++++R E+R++R +R + + ++E+ RR+ +E EK + + +++ ++ +
Sbjct: 791 RE--QRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQ 848
Query: 256 IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSE 315
+ E + E + + + ++ D+K + E+ +K + L + A + L K
Sbjct: 849 LQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ--LRKEQQLL 906
Query: 316 LKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKER---YEKEKT 372
++E+ + E+ R +E+ER+Y R++E++ +E E+L R+E E+RR++ER Y K+K
Sbjct: 907 QEEEEELQREEREKRRRQEQERQY-REEEQLQQEEEQLLREEREKRRRQERERQYRKDKK 965
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPG 432
++KEE++ E+ +K ++ E + E+ +++EE + R+ +++ Q ++
Sbjct: 966 LQQKEEQLLGEEP---EKRRRQEREKKYREEEELQQEEEQLLRE---EREKRRRQEWERQ 1019
Query: 433 ARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
R ++ L ++ + R QE +R+E
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREE 1053
Score = 92.0 bits (227), Expect = 1e-18
Identities = 78/280 (27%), Positives = 150/280 (53%), Gaps = 32/280 (11%)
Query: 204 LKNKQRMREEKREER--RRREIERKRQR----EEERRKW-KEEEKRKRKDIEKLKKIDRI 256
L+ +Q++R E+ EER ++ E ER+ QR +EERR W K EE+ +R + E+ K+ +
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLK- 477
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSEL 316
RD+ ++E + + LK E+ ++ ++RE+ + ++E ++R Q +R L
Sbjct: 478 --RDQ-EEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE--EEERLQQRL 532
Query: 317 KDEKPKRPEDESGRDY---RERERE--YERDQERILRERER-----LKRQEEER-----R 361
+ E+ R E E R+ RE E+ ER ++R+ RE+E LKR+EE R R
Sbjct: 533 RSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKR 592
Query: 362 RQKERYE---KEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRI 418
Q+ER E K + +R E+E ++E+ R++ ++ + + S E+ E++++ ++R++
Sbjct: 593 EQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQ 652
Query: 419 RNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
+++ ++ + R RL + + AE +QE
Sbjct: 653 ERREQ-RLKREEEEERLEQRLKREHEEERREQELAEEEQE 691
Score = 90.5 bits (223), Expect = 3e-18
Identities = 60/272 (22%), Positives = 147/272 (54%), Gaps = 25/272 (9%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQR 229
D + L EE + R+ ++ L + ++ ++ +R+RR+ E RQR
Sbjct: 118 DQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQR 177
Query: 230 EEERRKWKEEEKRKRKDIE----KLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKR 285
+E W+E E+R+ ++ + K + + P+ ++L+ ++L +K +EK+ +R
Sbjct: 178 QE----WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR--EEKQQQRR 231
Query: 286 EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPED---------ESGRDYRERE 336
E+ ++ +E +E+ + T+ ++ + +L++E+P+R + + R RE
Sbjct: 232 ERQDRVFQE--EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289
Query: 337 REYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAES 396
R+ E Q++ LR ++L+R++EE RR+++ +E+ +R+++E ++E+ R++ ++ E
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE- 348
Query: 397 TESIGSSEKTEKKEEVVKRDRIRNKDRPAMQL 428
+ + ++ E++E+ ++R+ + ++R QL
Sbjct: 349 -QQLRREQEEERREQQLRRE--QEEERREQQL 377
Score = 90.1 bits (222), Expect = 4e-18
Identities = 57/223 (25%), Positives = 134/223 (60%), Gaps = 15/223 (6%)
Query: 204 LKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLK 263
L+ +++ REEK+++RR R+ +R Q EEE+ +W++ E RK+ EKL++ + +R+ +
Sbjct: 216 LELRRKGREEKQQQRRERQ-DRVFQEEEEK-EWRKRETVLRKEEEKLQEEEPQRQRELQE 273
Query: 264 DEPKIKLLKKPEKGDEKELDKREKAKKLDKENL----SDERASGQSCTLPKRSDSELKDE 319
+E +++ L++ E E++ +++++ + ++ L +ER Q +R E +++
Sbjct: 274 EEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQE---ERREQQERREQ 330
Query: 320 KPKRPEDESGRDYRE-REREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEE 378
+ +R E + R+ E RE++ R+QE RE++ + QEEERR Q+ R E++ R+E+
Sbjct: 331 QEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ---LRREQ 387
Query: 379 EMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK 421
++++E+ R++ + E + + ++ +++++ + ++R +
Sbjct: 388 QLRREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRRE 428
Score = 87.8 bits (216), Expect = 2e-17
Identities = 72/275 (26%), Positives = 147/275 (53%), Gaps = 22/275 (8%)
Query: 167 YATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERK 226
Y D + + L EE E + R+ KK + ++++ E+RE+RRR+E ER+
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 227 RQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDK-LKDEPKIKLLKKPEKGDEKELDKR 285
++++E ++ EEE+ R++ EK R+ ER++ ++E +++ ++ G+E+E +R
Sbjct: 1020 YRKKDELQQ--EEEQLLREEREKR----RLQERERQYREEEELQQEEEQLLGEERETRRR 1073
Query: 286 EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQER 345
++ L+++ +E L + + L++E KR E R RE E E ++++E+
Sbjct: 1074 QE---LERQYRKEEE-------LQQEEEQLLREEPEKRRRQERERQCREEE-ELQQEEEQ 1122
Query: 346 ILR-ERERLKRQEEERR-RQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSS 403
+LR ERE+ +RQE ER+ R++E ++E+ +EE K+ + L + ++ E +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ--EE 1180
Query: 404 EKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNR 438
E+ ++E+ +R + R +L + + R R
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Score = 85.5 bits (210), Expect = 9e-17
Identities = 76/369 (20%), Positives = 189/369 (51%), Gaps = 45/369 (12%)
Query: 136 FQKAAKKKTKKRDTKVGTIDD-----DPEYRKFLESYATDNEKMTSTPETLLEEIEAKNR 190
FQ+ +K+ +KR+T + ++ +P+ ++ L+ K+ + E + +
Sbjct: 238 FQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 191 ELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQR------EEER-----RKWKEE 239
+ + ++ + ++ +EE+RE++ RRE + +R+ +EER R+ +EE
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 240 EKRK---RKDIEKLKKIDRIPERDKLKDEPKIK----LLKKPEKGDEKELDKREKAKKLD 292
E+R+ R++ E+ ++ ++ +L+ E +++ L ++ + E++L + ++ ++
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 293 KENLSDE-RASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERE 351
+ + R + ++ + E ++++ KR E E RD+ +RE E ER ++ R ++
Sbjct: 418 QLRREQQLRREQEEERHEQKHEQERREQRLKR-EQEERRDWLKREEETERHEQE--RRKQ 474
Query: 352 RLKRQEEERRRQK----ERYEKEKTFKRKEEEMKKEKDTLRDKG-KKAESTESIGS---- 402
+LKR +EE RR++ E E+ + +R+E+++++E++ R++ K+ E E +
Sbjct: 475 QLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRS 534
Query: 403 -----SEKTEKKEEVVKRDRIR--NKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAER 455
E+ E++E+++KR+ + ++R +L + R++L ++ + +R
Sbjct: 535 EQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR--QQRLKR 592
Query: 456 KQESGISHR 464
+QE + R
Sbjct: 593 EQEERLEQR 601
Score = 84.3 bits (207), Expect = 2e-16
Identities = 62/245 (25%), Positives = 130/245 (53%), Gaps = 20/245 (8%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRK--WKEEE 240
EE A+ +L + K F +Q R E E RR+ E+++QR E + + +EEE
Sbjct: 184 EERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEE 243
Query: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER 300
K RK L+K E +KL++E +P++ E + ++ E+ +KL+++ L ER
Sbjct: 244 KEWRKRETVLRK-----EEEKLQEE-------EPQRQRELQ-EEEEQLRKLERQELRRER 290
Query: 301 ASGQSCTLPKRSDSEL--KDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEE 358
+ R + +L K E+ +R + E R+ +ER + E +E+ LR + +R+++
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 359 ERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRI 418
RR Q+E +E+ +R++EE ++E+ R++ + E + + ++ +++++ + ++
Sbjct: 351 LRREQEEE-RREQQLRREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQL 407
Query: 419 RNKDR 423
R + +
Sbjct: 408 RREQQ 412
Score = 84.3 bits (207), Expect = 2e-16
Identities = 59/233 (25%), Positives = 129/233 (55%), Gaps = 19/233 (8%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
+ KQ+++ ++ EERR R ++ + + E+++ +E++ R+ ++ + +++ R E ++L+
Sbjct: 471 RRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQ 530
Query: 265 EPKIKLLKKPEKGDEKE-LDKREKAKKLDKENLS-------DERASGQSCTLPKRSDSEL 316
+ + + E+ + +E L KRE+ K+L++E +ER +R L
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRL 590
Query: 317 KDEKPKRPEDESGRDYREREREYERDQERILRE-------RERLKRQEEERRRQKERYEK 369
K E+ +R E R+ ER + ER ++R+ RE ++ LK +E+E RRQ++ +
Sbjct: 591 KREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRRE 650
Query: 370 EKTFKRKEEEMKKEKDTLR-DKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK 421
++ +R+E+ +K+E++ R ++ K E E E E+++E R+RI+++
Sbjct: 651 QQ--ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQA-RERIKSR 700
Score = 84.3 bits (207), Expect = 2e-16
Identities = 82/309 (26%), Positives = 164/309 (53%), Gaps = 30/309 (9%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKR------EERRRREIERKRQREEER-RK 235
+E + K RE + P FL+ +Q++ ++R EE++ R ER +QR ++R RK
Sbjct: 1497 QERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRK 1556
Query: 236 WKEEEK-RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEK--GDEKELDKREKAKKLD 292
++EEE+ R+ ++ ++L + +R +R +E K++ ++ K DE++L ++E ++L
Sbjct: 1557 FREEEQLRQEREEQQLSRQER--DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR 1614
Query: 293 KENLSDERASGQSCTLPKRSDSELKDEKPKRP--EDESGRDYREREREYERDQERILRER 350
+E D + L +R + +L ++ R E+E +ERE++ D++R RE
Sbjct: 1615 QER--DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 351 ERLKRQEEE---RRRQKER--YEKEKTFKRKEEEMK--KEKDTLRDKGKKAESTESIGSS 403
E+L ++ EE RR++++R E+E+ +R+E E K +E+ LR + + + E
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 404 EKTEKKEEVVKRDRIR-----NKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAE-RKQ 457
++TE +E++ +++R R + RP + Q + R+R ++ + + R Q
Sbjct: 1733 QETE-QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQ 1791
Query: 458 ESGISHRKE 466
ES R+E
Sbjct: 1792 ESDRKFREE 1800
Score = 82.8 bits (203), Expect = 6e-16
Identities = 77/356 (21%), Positives = 172/356 (48%), Gaps = 30/356 (8%)
Query: 136 FQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAK 195
+Q +K+ RD KV + E + LE + + + LL E + ++RE +
Sbjct: 1225 WQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERR 1284
Query: 196 KTTPL-LSFLKNKQRMREEKREERRR-----REIERKRQREEERRKWKEEEKRKRKDIEK 249
+ F + +Q REE++E +RR E + R+ EE+R+ +E +++ R++ +
Sbjct: 1285 RWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQL 1344
Query: 250 LKKIDRIP----ERDKLKDEPKIKLLKKPEK--GDEKELDKREKAKKLDKENLSDERASG 303
L++ + P ERD+ E +++ ++ K +E+ L ++E+ +K KE R
Sbjct: 1345 LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE-QQLRCQE 1403
Query: 304 QSCTLPKRSDSELKDEKPKRPEDESGRDYR---------EREREYERDQERILRERERLK 354
+ L + D + ++E+ + E R +R ERER++ +++++ +ER R
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 355 RQEEERRRQKE-----RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKK 409
R+EE+ +++E R E+++ F +E+++++++ RD+ + + S K ++
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQE---RDRKFREQELRSQEPERKFLEE 1520
Query: 410 EEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRK 465
E+ + R + + K Q + R + R D + + + ++E +S ++
Sbjct: 1521 EQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576
Score = 79.7 bits (195), Expect = 5e-15
Identities = 84/367 (22%), Positives = 170/367 (46%), Gaps = 72/367 (19%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
Q+ +++ ++R+ ++ +++ ++ L S E L + + RE + K+
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRS------------EQQLRREQEERREQLLKR 552
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKR----QREEERRKW---KEEEKR-----KR 244
+ ++R+ +E+RE+R +RE E +R +REEERR+ +E+E+R KR
Sbjct: 553 --------EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKR 604
Query: 245 KDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQ 304
+++E+L++ +R +R LK E +PE+ ++L K E+ ++ ++ L E+ +
Sbjct: 605 EEVERLEQEERREQR--LKRE-------EPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 305 SCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERI------------------ 346
L + + E +++ KR +E R+ E E E+ +ERI
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR 715
Query: 347 -LRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEK 405
+ R ++QE +RRRQ+ ++EK +R+ E +E++ + ++ E +
Sbjct: 716 QSKVYSRPRKQEGQRRRQE---QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQ 772
Query: 406 TEKKEEVVKRDRIRNKDRPAM------QLYQPGARSRNRLCPPDDSTKSGDSAAERKQES 459
E+K E R R R RP + QL + R + P++ K R++E
Sbjct: 773 AEEKSE---RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREK 829
Query: 460 GISHRKE 466
+ +E
Sbjct: 830 ELQFLEE 836
Score = 79.3 bits (194), Expect = 7e-15
Identities = 72/342 (21%), Positives = 171/342 (50%), Gaps = 46/342 (13%)
Query: 121 DNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEY---------RKFLESYATDN 171
D K QE ++ +K +++T ++ + + + E RKF E
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQ 1370
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE 231
E+ LEE + R+ +K FLK +Q++R ++RE++ R++ +RK + EE
Sbjct: 1371 EQ----GRKFLEEEQRLRRQERERK------FLKEEQQLRCQEREQQLRQDRDRKFREEE 1420
Query: 232 ERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKL 291
++ +E +++ R++ +++++ +R ER L++E +++ + + +E++L + + ++L
Sbjct: 1421 QQLSRQERDRKFREEEQQVRRQER--ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL 1478
Query: 292 -----DKENLSDERASGQSCTLPKRSDSELKDEKPKRP----EDESGRDYRER------- 335
D++ L +E+ + K + EL+ ++P+R E + R R+R
Sbjct: 1479 HRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQ 1538
Query: 336 -----EREYER--DQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLR 388
ER +R D++R RE E+L+++ EE +Q R E+++ F+ +E+++++++ +
Sbjct: 1539 QLRRQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQERK 1596
Query: 389 DKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQ 430
+ + G + ++++ + D ++R QL++
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638
Score = 78.6 bits (192), Expect = 1e-14
Identities = 57/225 (25%), Positives = 120/225 (53%), Gaps = 20/225 (8%)
Query: 207 KQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEP 266
+QR ++REERR E + + + E ++ +EE+ +R+++ +L++ R E+ + + E
Sbjct: 175 RQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGR-EEKQQQRRER 233
Query: 267 KIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQ------SCTLPKRSDSELKDEK 320
+ ++ ++ E EKE KRE + ++E L +E Q L K EL+ E+
Sbjct: 234 QDRVFQEEE---EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290
Query: 321 PKRPEDESG----RDYREREREYERDQERILRERERLKRQEEERRRQKERYE----KEKT 372
+ + + + R ++ E R+Q+ RE++ + Q+EERR Q+ R E +E+
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDR 417
+R++EE ++E+ R+ ++ E E E+ ++E+ ++R++
Sbjct: 351 LRREQEEERREQQLRRE--QEEERREQQLRREQQLRREQQLRREQ 393
Score = 77.4 bits (189), Expect = 3e-14
Identities = 64/246 (26%), Positives = 123/246 (50%), Gaps = 35/246 (14%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEER--RKWKEEEKRKRKDIEKLKKIDRIPERDKL 262
+ ++R ++ +RE+ RRE KRQ EEER ++ + E++ +R+ E+ +++ + E +L
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRL 558
Query: 263 KDEPKIKLLKKPEKGDEKELDKRE------KAKKLDKENLSD--ERASGQSCTLPKRSDS 314
+ E + + LK+ ++ +L KRE + K+ +E L +R + +R +
Sbjct: 559 EQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQ 618
Query: 315 ELKDEKP---------KRPEDESGRDYREREREYERDQERILRERE------RLKRQEEE 359
LK E+P K E E R + R + ER ++R+ RE E RLKR+ EE
Sbjct: 619 RLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEE 678
Query: 360 RRRQKERYEKEKTFKRK---------EEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKE 410
RR++E E+E+ R+ + +++ E D + K + + G + E++E
Sbjct: 679 ERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK-VYSRPRKQEGQRRRQEQEE 737
Query: 411 EVVKRD 416
+ +R+
Sbjct: 738 KRRRRE 743
Score = 77.4 bits (189), Expect = 3e-14
Identities = 75/336 (22%), Positives = 166/336 (49%), Gaps = 46/336 (13%)
Query: 136 FQKAAKKKTKKRDTKVGTIDDDPEYRKFLE---SYATDNEKMTSTPETLLEEIEAKNREL 192
+++ +KK + + + + ++ E R+ E Y + E + L EE E + R+
Sbjct: 1016 WERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQE 1075
Query: 193 IAKKTTPLLSFLKNKQRMREEKREERRRREIERK------RQREEERRKWKEEEKRKRKD 246
+ ++ + ++++ E+ E+RRR+E ER+ Q+EEE+ +E EKR+R++
Sbjct: 1076 LERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQE 1135
Query: 247 IEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKR----EKAKKLDKENLSDERAS 302
+E+ + E ++++ E + L ++PEK +EL+++ E+ ++ +++ L +E+
Sbjct: 1136 LERQYR-----EEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Query: 303 G-QSCTLPKRSDSELKDEKPKR----------------PEDESG-RDYREREREYERDQE 344
Q R + EL+ +K K+ PE E+ RD + + E +Q
Sbjct: 1191 RRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQF 1250
Query: 345 RILRE---RERLKRQEEE----RRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAEST 397
R L + R+R +Q+ + +++++R ++ + +++++ +E+ R++ K+A+
Sbjct: 1251 RQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRR 1310
Query: 398 ESIGSSEK---TEKKEEVVKRDRIRNKDRPAMQLYQ 430
+ EK E++EE +R K R QL Q
Sbjct: 1311 DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQ 1346
Score = 77.4 bits (189), Expect = 3e-14
Identities = 68/285 (23%), Positives = 149/285 (52%), Gaps = 30/285 (10%)
Query: 201 LSFLKNKQRMREE----KREERRRREIERKRQ-REEERRKWKEEEK-RKRKDIEKLKKID 254
LS + ++ REE +R+ER R+ +E ++Q R+E RK++EEE+ + ++ ++L + +
Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482
Query: 255 RIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDS 314
R +R L++E +++ ++ K E+EL +E +K +E Q +R
Sbjct: 1483 R--DRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEE--------QQLHRQQRQRK 1532
Query: 315 ELKDEKPKRPEDESGRDYREREREY-ERDQERILRERERLKRQEEERRRQKE-----RYE 368
L++E+ R ++ + ++R+R++ E +Q R RE ++L RQE +R+ + E R E
Sbjct: 1533 FLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQE 1592
Query: 369 KEKTFKRKEEEMKK---EKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPA 425
+E+ F E+++++ ++ +++ +K E + E+ E++ +RDR ++ P
Sbjct: 1593 QERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL-LQEREEQQLHRQERDRKFLEEEPQ 1651
Query: 426 MQLYQPGARSRN----RLCPPDDSTKSGDSAAERKQESGISHRKE 466
++ + + R+ + + + G+ R+QE R+E
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE 1696
Score = 77.0 bits (188), Expect = 3e-14
Identities = 70/307 (22%), Positives = 160/307 (52%), Gaps = 39/307 (12%)
Query: 145 KKRDTKVGTIDDDPEYRKFL--ESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLS 202
++RD K ++++P+ R+ + D ++ E LL+E E + ++
Sbjct: 1639 QERDRKF--LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ----LRRQERDRK 1692
Query: 203 FLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKL 262
F + +Q++R ++RE + +E ++ R++E ER+ +EE+ R+ + E+L++ +R K+
Sbjct: 1693 FREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR---KI 1749
Query: 263 KDEPKIKLLKKPEKGDEKELDKREKAKKL-DKENLSDERASGQSCTLPKRSDSELKDEKP 321
+E +++ PE+ +E++L ++E+ +K ++E L ER Q + + SD + ++E+
Sbjct: 1750 LEEEQLR----PER-EEQQLRRQERDRKFREEEQLRQEREEQQLRS--QESDRKFREEEQ 1802
Query: 322 KRPEDESGRDYREREREYERDQERILR---ERERLKRQEEERRRQKER---YEKEKTFKR 375
R +ERE + R Q+R + E E+L+ +E+E+R ++ER Y E+ F
Sbjct: 1803 LR---------QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFAT 1853
Query: 376 KEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARS 435
+E+ ++E++ +++ +K E+ ++E + ++ + + R ++ +
Sbjct: 1854 QEKSRREEQELWQEEEQKRRQ-----ERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908
Query: 436 RNRLCPP 442
RL P
Sbjct: 1909 HGRLLEP 1915
Score = 74.7 bits (182), Expect = 2e-13
Identities = 66/310 (21%), Positives = 149/310 (48%), Gaps = 31/310 (10%)
Query: 156 DDPEYRKF--LESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREE 213
++PE R+ LE + E++ E LL E + K R+ ++ +Q+ ++
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEEL--QRQKRKQR 1213
Query: 214 KREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKK 273
R+E +R +++ + + E+E + K ++ E+ ++++ RD+ + LL +
Sbjct: 1214 YRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGE 1273
Query: 274 PEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEK--------PKRPE 325
++ D ++ +R + ++ D+ +E+ + KR D + ++EK KR
Sbjct: 1274 QQERDREQ--ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRR 1331
Query: 326 DESGRDYREREREYERDQERILRERERLKRQEEERRRQKE-------------RYEKEKT 372
E+ R +RE E+ + +E+ LR +ER ++ EE R +E R E+E+
Sbjct: 1332 QETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERK 1391
Query: 373 FKRKEEEMK---KEKDTLRDKGKK-AESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQL 428
F ++E++++ +E+ +D+ +K E + + E+ K E ++ R + ++R ++
Sbjct: 1392 FLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEE 1451
Query: 429 YQPGARSRNR 438
Q + R+R
Sbjct: 1452 EQQLRQERHR 1461
Score = 70.5 bits (171), Expect = 3e-12
Identities = 88/348 (25%), Positives = 149/348 (42%), Gaps = 71/348 (20%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIER-------KRQREEERRK 235
EE E + R+ + K + +R ++E+RE+R +RE E KR+ EEERR+
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE 682
Query: 236 WKEEEKRKRKDIEKLKKIDRIP----ERDKLKDEPKIKLLKKPEK--GDEKELDKREKAK 289
+ E+ + + E++K RIP + + D + K+ +P K G + ++ EK +
Sbjct: 683 QELAEEEQEQARERIKS--RIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR 740
Query: 290 KLDKENL--SDERASGQSCTLPKRSD------SELKDEKPK-----------------RP 324
+ + E +ERA Q +R D +E K E+ + R
Sbjct: 741 RRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRA 800
Query: 325 EDESGRDYR----EREREYERDQER-------ILRERERLKRQE---------------E 358
E+ R+ R E E+E R Q R L E E+L+R+E +
Sbjct: 801 EERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQ 860
Query: 359 ERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRI 418
ERRR +E+ +K + EEE K+ + TL K E + +++EE ++R+
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK--EQQLLQEEEEELQREE- 917
Query: 419 RNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
R K R Q Q R +L ++ + R+QE +RK+
Sbjct: 918 REKRRRQEQERQ--YREEEQLQQEEEQLLREEREKRRRQERERQYRKD 963
Score = 65.5 bits (158), Expect = 1e-10
Identities = 60/245 (24%), Positives = 119/245 (48%), Gaps = 15/245 (6%)
Query: 238 EEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLS 297
+EEKR R D ++ DR E D+ + EP+ + L++ E G + ++E+ ++L +
Sbjct: 96 DEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEE-EPGQRRRQKRQEQERELAEGEEQ 154
Query: 298 DERASGQSCTLPKRSDSEL-------KDEKPKRPEDESGRDYREREREYERDQERILRER 350
E+ +R D EL ++ + +R E+E + + E E D+E+ LR R
Sbjct: 155 SEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ-LRRR 213
Query: 351 ERL---KRQEEERRRQKERYEKEKTFKRKEE-EMKKEKDTLRDKGKKAESTESIGSSEKT 406
E L ++ EE+++Q+ R +++ F+ +EE E +K + LR + +K + E E
Sbjct: 214 ELLELRRKGREEKQQQR-RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Query: 407 EKKEEVVKRDRIR-NKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRK 465
E++E++ K +R ++R + Q R +L + + R+Q+ ++
Sbjct: 273 EEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQE 332
Query: 466 EGGEE 470
E E+
Sbjct: 333 ERREQ 337
Score = 46.2 bits (108), Expect = 6e-05
Identities = 38/177 (21%), Positives = 86/177 (48%), Gaps = 23/177 (12%)
Query: 277 GDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE-R 335
G LD+ ++A+ KE+L +R + + D +L++E +R + RE
Sbjct: 90 GQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELA 149
Query: 336 EREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEM--------------- 380
E E + +++ L +R+R +R++EE RQ++ +++ + + +EE++
Sbjct: 150 EGEEQSEKQERLEQRDR-QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEE 208
Query: 381 ---KKEKDTLRDKGKKAESTESIGSSEKT---EKKEEVVKRDRIRNKDRPAMQLYQP 431
++E LR KG++ + + ++ E+++E KR+ + K+ +Q +P
Sbjct: 209 QLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Score = 32.0 bits (71), Expect = 1.2
Identities = 34/184 (18%), Positives = 81/184 (44%), Gaps = 21/184 (11%)
Query: 304 QSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERR-- 361
Q+C + L +EK R + G++ ++R E DQ R +L+ + +RR
Sbjct: 83 QACYYALGQATGLDEEKRARCD---GKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQ 139
Query: 362 -RQKERYE--------------KEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKT 406
RQ++ E +++ +R++EE+ +++ +++ ++ E + S K
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSC-KG 198
Query: 407 EKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
+ EE +++R ++ ++ + + R D + + RK+E+ + +E
Sbjct: 199 HETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEE 258
Query: 467 GGEE 470
+E
Sbjct: 259 KLQE 262
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 98.2 bits (243), Expect = 1e-20
Identities = 57/207 (27%), Positives = 115/207 (55%), Gaps = 22/207 (10%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
+ +R +E + E+R+RE E++R+RE +++ K+ +KR+R + K+ +R +R + ++
Sbjct: 32 RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 265 EPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRP 324
+ + K K+ +K + K+ +RE+ KK KE ER + K +R
Sbjct: 92 KERRKRKKEKKKRERKQRGRRERKKK--KERKERER-----------------ENKQRRE 132
Query: 325 EDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEK 384
R ++R +E +R++ER RER+R KR++EER +++ER KE ++KE E K+ +
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE---RKKERERKERR 189
Query: 385 DTLRDKGKKAESTESIGSSEKTEKKEE 411
+ +++ K+ + KT+++ +
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTD 216
Score = 86.3 bits (212), Expect = 6e-17
Identities = 64/222 (28%), Positives = 119/222 (53%), Gaps = 32/222 (14%)
Query: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL 270
RE +R++ RR +RKR+RE+ER++ +R +K+ +K KK +R ER++ + E +
Sbjct: 32 RESERKKERREREKRKREREKERKR-----ERGKKEKKKRKKRERGKERERKRKERE--- 83
Query: 271 LKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
K+ ++ EKE KR+K KK + +R E K +K ++ + +
Sbjct: 84 -KQRKERREKERRKRKKEKKKRERK--------------QRGRRERKKKKERKERERENK 128
Query: 331 DYREREREYERDQERILRERERLKRQEEERRRQK-ERYEKEKTFKRKEEEMKKEKDTLRD 389
RER+R+ R ++R + +R + ER+R+K ++ E+EK +R +E KKE++
Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188
Query: 390 KGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQP 431
+ +K E E+ +KKE K+DR ++ + Q+++P
Sbjct: 189 RERKKER-----KKERRKKKER--KKDRKTDRQTDS-QVFRP 222
Score = 84.0 bits (206), Expect = 3e-16
Identities = 68/199 (34%), Positives = 104/199 (52%), Gaps = 37/199 (18%)
Query: 228 QREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREK 287
QRE ER+K + E ++++++ EK +K R++ K E K + KK E+G E+E ++E+
Sbjct: 31 QRESERKKERREREKRKREREKERK------RERGKKEKKKR--KKRERGKERERKRKER 82
Query: 288 AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL 347
K+ KE ER + K EK KR + GR RER+++ ER
Sbjct: 83 EKQR-KERREKERR-------------KRKKEKKKRERKQRGR--RERKKKKER------ 120
Query: 348 RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKE---KDTLRDKGKKAESTESIGSSE 404
+ERER +Q ER+R+K R +K +RKE + +KE ++ R K KK E + +
Sbjct: 121 KERERENKQRRERKRKKRRKKK----RRKERKREKERGKRERKRKKRKKEEREKKRERNR 176
Query: 405 KTEKKEEVVKRDRIRNKDR 423
K KKE K R R K+R
Sbjct: 177 KERKKERERKERRERKKER 195
Score = 82.0 bits (201), Expect = 1e-15
Identities = 57/208 (27%), Positives = 110/208 (52%), Gaps = 17/208 (8%)
Query: 176 STPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKR---QREEE 232
S P T E K R K+ K ++ +E+K+ ++R R ER+R +RE++
Sbjct: 26 SKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQ 85
Query: 233 RRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD 292
R++ +E+E+RKRK +K ++ + R++ K + + + ++ ++ E++ KR K K+
Sbjct: 86 RKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRK 145
Query: 293 KENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERER 352
+ ER E K +K K+ E E R+ +ER+ ER+++ RER
Sbjct: 146 ERKREKERGK-----------RERKRKKRKKEEREKKRERNRKERKKERERK---ERRER 191
Query: 353 LKRQEEERRRQKERYEKEKTFKRKEEEM 380
K +++ERR++KER + KT ++ + ++
Sbjct: 192 KKERKKERRKKKERKKDRKTDRQTDSQV 219
Score = 68.2 bits (165), Expect = 2e-11
Identities = 50/191 (26%), Positives = 95/191 (49%), Gaps = 10/191 (5%)
Query: 271 LKKP--EKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDES 328
+ KP ++ E++ ++RE+ K+ + +R G+ ++ K+ + KR E E
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 329 GRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFK-RKEEEMKKEKDTL 387
R +ER + R +++ ++RER +R ER+++KER E+E+ K R+E + KK +
Sbjct: 85 QR--KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKK 142
Query: 388 RDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTK 447
R K +K E G E+ KK + +R++ R ++R + + R R + K
Sbjct: 143 RRKERKREKER--GKRERKRKKRKKEEREKKRERNRKERKKERERKERRER---KKERKK 197
Query: 448 SGDSAAERKQE 458
ERK++
Sbjct: 198 ERRKKKERKKD 208
Score = 61.6 bits (148), Expect = 1e-09
Identities = 48/162 (29%), Positives = 84/162 (51%), Gaps = 15/162 (9%)
Query: 322 KRPEDESGRDYREREREYERDQERILRERERLK-----------RQEEERRRQKERYEKE 370
+R ++ R+ R+RERE ER +ER +E+++ K R+E E++R KER EKE
Sbjct: 35 ERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQR-KERREKE 93
Query: 371 KTFKRKEEEMKKEKDT--LRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQL 428
+ KRK+E+ K+E+ R++ KK E E +++ +++ +R + R K+R +
Sbjct: 94 RR-KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152
Query: 429 YQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
R R + + K + ERK+E R+E +E
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 97.1 bits (240), Expect = 3e-20
Identities = 94/325 (28%), Positives = 141/325 (43%), Gaps = 34/325 (10%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQR 229
D + S + + K E KK K ++ E+ ER RRE ER+R+R
Sbjct: 272 DKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRERERERER 331
Query: 230 EEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAK 289
E ER K KE E+ + +D ++ DR ERD+ +D + + + D + R + K
Sbjct: 332 EREREKEKERERERERDRDR----DRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREK 387
Query: 290 KLDKENLSD---ERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERERE-YERDQ-E 344
D+E + ER + + + E + E+ + E + RD E E + YER + E
Sbjct: 388 SRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLE 447
Query: 345 RILRER-----ERLKRQEEERRRQKERYEKEKTFKRKEE---EMKKEKDTL--------- 387
R LRE+ ERLK E R++ YEKE +R+EE EM KE L
Sbjct: 448 RKLREKEAAYQERLKNWEIRERKKTREYEKEA--EREEERRREMAKEAKRLKEFLEDYDD 505
Query: 388 -RDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCP-PDDS 445
RD K + EK+ E +RDR R K+ +L + R P PD
Sbjct: 506 DRDDPKYYRGSALQKRLRDREKEMEADERDRKREKE----ELEEIRQRLLAEGHPDPDAE 561
Query: 446 TKSGDSAAERKQESGISHRKEGGEE 470
+ + AER+++ I E EE
Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEE 586
Score = 92.8 bits (229), Expect = 6e-19
Identities = 71/243 (29%), Positives = 122/243 (50%), Gaps = 53/243 (21%)
Query: 184 EIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERR-----RREIERKRQREEERRKWKE 238
E+E R+LI+++ + K + + +K +ER+ RRE ER+R+RE ERR+ +E
Sbjct: 268 EMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERRE-RE 326
Query: 239 EEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK-REKAKKLDKENLS 297
E+ + ++ EK K+ +R ERD+ +D K E++ D+ RE+ + D+E S
Sbjct: 327 REREREREREKEKERERERERDRDRDRTK-----------ERDRDRDRERDRDRDRERSS 375
Query: 298 DERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQE 357
D R +D S + R+RE ER++E RERER + +E
Sbjct: 376 D------------------------RNKDRSRSREKSRDRERERERE---RERERERERE 408
Query: 358 EERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDR 417
ER R++ER +E E ++EKD RD+ + E E+ +++E ++R
Sbjct: 409 RERERERER--------EREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQER 460
Query: 418 IRN 420
++N
Sbjct: 461 LKN 463
Score = 84.7 bits (208), Expect = 2e-16
Identities = 69/257 (26%), Positives = 128/257 (49%), Gaps = 19/257 (7%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
++++R RE +RE R RE ER+R+RE ER + +E E+ K K ++ + + ER KL+
Sbjct: 389 RDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLER 448
Query: 265 EPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKR- 323
+ + K E+ E+ +R+K ++ +KE +E + KR L+D R
Sbjct: 449 KLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508
Query: 324 -PEDESGRDYREREREYERDQERILRERERLKRQEEERRR------------QKERYEKE 370
P+ G ++R R+ E++ E R+R+R K + EE R+ + +R E+E
Sbjct: 509 DPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQE 568
Query: 371 KTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQ 430
+R++ ++K+E ++ ++ +K E E E E++EE ++ ++ RP
Sbjct: 569 AE-RRRQPQIKQEPESEEEEEEKQEKEEK--REEPMEEEEEPEQKPCLKPTLRPISSAPS 625
Query: 431 PGARSRNRL--CPPDDS 445
+ S N P D+S
Sbjct: 626 VSSASGNATPNTPGDES 642
Score = 60.8 bits (146), Expect = 2e-09
Identities = 76/310 (24%), Positives = 128/310 (41%), Gaps = 53/310 (17%)
Query: 178 PETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWK 237
PE+ L + + I +K + K K ++ E K +++ R + +
Sbjct: 137 PESTLRALRLLHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEAL 196
Query: 238 EEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD----- 292
+EE ++R + +K + R+ + L P + + K++K KK D
Sbjct: 197 DEETKRRDQM--IKGAIEVLIREYSSE------LNAPSQESDSHPRKKKKEKKEDIFRRF 248
Query: 293 ------------KENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYE 340
KE+++ L R S+ +D K E++ ++ +E E E
Sbjct: 249 PVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKE 308
Query: 341 RDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI 400
R + RERER +R E ER R++ER E+E K KE E ++E+D RD+ K+
Sbjct: 309 RRERERERERERERR-ERERERERER-ERE---KEKERERERERDRDRDRTKE------- 356
Query: 401 GSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESG 460
++ +E RDR R+ DR RSR+R KS D ER++E
Sbjct: 357 --RDRDRDRERDRDRDRERSSDRNK-------DRSRSR-------EKSRDRERERERERE 400
Query: 461 ISHRKEGGEE 470
+E E
Sbjct: 401 RERERERERE 410
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 96.3 bits (238), Expect = 5e-20
Identities = 76/338 (22%), Positives = 167/338 (49%), Gaps = 26/338 (7%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNR--ELIA 194
+K +++ K R+ + + + + R+ E EKM E + E+ E R E++
Sbjct: 314 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMW 373
Query: 195 KKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKID 254
+K + + + E+ E+ + RE E KRQ EE K +E+EKR+ ++ + ++ +
Sbjct: 374 EKEEKI-------RELEEKMHEQEKIREQEEKRQEEE---KIREQEKRQEQEAKMWRQEE 423
Query: 255 RIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDS 314
+I E+++ E + K+ ++ EK E+E + E+ ++ +E E + + ++ +
Sbjct: 424 KIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 483
Query: 315 ELKDEKPKRPEDESGRD----------YREREREYERDQERILRERERLKRQEEERRRQK 364
+ EK ++ E++ R RE+E + R +E+I + E+++ QEE+ R Q+
Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543
Query: 365 E-RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI-GSSEKTEKKEEVV--KRDRIRN 420
E E+E+ +EE+M++++ R + K E E I EK ++EE + + ++IR
Sbjct: 544 EMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE 603
Query: 421 KDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
++ + + ++C ++ + + R++E
Sbjct: 604 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 641
Score = 85.1 bits (209), Expect = 1e-16
Identities = 58/297 (19%), Positives = 145/297 (48%), Gaps = 12/297 (4%)
Query: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
L + + E + ++ + + + Q E+ RE+ + + ++ R +E W++EE
Sbjct: 290 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 349
Query: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER 300
K +R++ +K +++ +++ E + K+ + EK E+E + ++ K+ ++E + ++
Sbjct: 350 KMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 409
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD---QERILRERERLKRQE 357
+ R + ++++++ K E E + +R+ E+ +E++ +E +E+E + RQE
Sbjct: 410 KRQEQEAKMWRQEEKIREQEEKIREQEK-KMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 468
Query: 358 EERR------RQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTES--IGSSEKTEKK 409
E+ R RQKE+ +++ +++EE++ ++++ + D+ +K E EK ++
Sbjct: 469 EKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQ 528
Query: 410 EEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
EE ++ + +++ M Q + R+QE I +KE
Sbjct: 529 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKE 585
Score = 84.3 bits (207), Expect = 2e-16
Identities = 71/306 (23%), Positives = 161/306 (52%), Gaps = 17/306 (5%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE 231
+++ + + L +E+++ + +L A+ L N+Q+ + R+E + +E E K Q +E
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 232 ERRKWKEEEKRKRKDIEKLKKIDRI----PERDKLKDEPKIKLLKKPEKGDEKELDKREK 287
E K +E+E++ R+ EK+++ + + E+ + ++E + +K + +E +K EK
Sbjct: 321 E--KIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEK 378
Query: 288 AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL 347
++L+++ E+ Q KR + E E+ KR E E+ R+ E R+QE +
Sbjct: 379 IRELEEKMHEQEKIREQE---EKRQEEEKIREQEKRQEQEA---KMWRQEEKIREQEEKI 432
Query: 348 RERE-RLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKT 406
RE+E ++ RQEE+ Q++ E+EK ++++EEM ++++ +R++ + E + EK
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEK--RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKI 490
Query: 407 EKKEEVVKR--DRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHR 464
K+EE V R +++ +++ + + R ++ ++ + + ++E
Sbjct: 491 RKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQE 550
Query: 465 KEGGEE 470
++ GE+
Sbjct: 551 EKMGEQ 556
Score = 78.6 bits (192), Expect = 1e-14
Identities = 56/221 (25%), Positives = 125/221 (56%), Gaps = 13/221 (5%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEK--REERRRREIERKR 227
+ EK E +E + + +E I ++ + + K R +EEK R+E + + E K
Sbjct: 454 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE--QEKIRKQEEKVWRQEEKMHDQEEKI 511
Query: 228 QREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREK 287
RE+E + W++EEK + ++ + ++ ++I E++++ E + K+ ++ EK E+E +R++
Sbjct: 512 -REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQE 570
Query: 288 AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL 347
K ++E E+ Q + ++ + + E+ R ++E ++ E+ E E E++
Sbjct: 571 EKIREQE----EKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQE---EKMC 623
Query: 348 RERERLKRQEEERRRQKE-RYEKEKTFKRKEEEMKKEKDTL 387
+ E+++ QEE+ RRQ+E +E+E +++EE+M++ ++ L
Sbjct: 624 EQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 664
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/242 (23%), Positives = 132/242 (54%), Gaps = 13/242 (5%)
Query: 179 ETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRR--REIERKRQREE---ER 233
E + E E K RE K + ++ EEKR+E+ R+ E+ R++EE ++
Sbjct: 422 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQK 481
Query: 234 RKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDK 293
K E+EK ++++ + ++ +++ ++++ E + K+ ++ EK E+E RE+ +K+ +
Sbjct: 482 EKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIRE 541
Query: 294 ENLSDERASGQSCTLPKRSDSELKDEKPKRPED---ESGRDYREREREYERDQERILRER 350
+ +E Q + ++ + + EK +R E+ E RE++ + +E+I +
Sbjct: 542 Q---EEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598
Query: 351 ERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKK 409
E+++ QEE + Q+E+ +E+E+ +EE+M+++++ +R + +K E + ++ EK
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE-VRLRQQEEKM 657
Query: 410 EE 411
+E
Sbjct: 658 QE 659
Score = 75.1 bits (183), Expect = 1e-13
Identities = 56/266 (21%), Positives = 145/266 (54%), Gaps = 16/266 (6%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
++ +++ K+++ + + + R+ E +KM E + E+ + + E K
Sbjct: 402 EEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE----K 457
Query: 197 TTPLLSFLKNKQRMREEKREERRRREI-ERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
+ ++++RE++ R++ ++ E+++ R++E + W++EEK ++ EK+++
Sbjct: 458 RQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQE-EKIRE--- 513
Query: 256 IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSE 315
E + E KI+ ++ + E+++ ++E+ + +E + ++ Q +R + +
Sbjct: 514 -QEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEK 572
Query: 316 LKDEKPK-RPEDESGRDYREREREYE---RDQERILRERE-RLKRQEEERRRQKERY-EK 369
+++++ K R + E R+ E+ E E R+QE +++E+E ++ QEE+ Q+E+ E+
Sbjct: 573 IREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Query: 370 EKTFKRKEEEMKKEKDTLRDKGKKAE 395
E+ +R+EE+M +++ LR + +K +
Sbjct: 633 EEKMRRQEEKMWEQEVRLRQQEEKMQ 658
Score = 47.4 bits (111), Expect = 3e-05
Identities = 68/315 (21%), Positives = 143/315 (45%), Gaps = 40/315 (12%)
Query: 135 PFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTP--ETLLEEIEAKN--- 189
P A TKK+ GT +PE ++ ++E+ S E L E+EA+
Sbjct: 76 PSVGTAASDTKKKKINNGT---NPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTI 132
Query: 190 RELIAKKTTPLLSFLKNKQRMREEKREERR-----------RREIERKRQREEERRKWKE 238
R L +KT ++ ++ +++ + E R E+E+ ++K +
Sbjct: 133 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 192
Query: 239 ---EEKRKRKDIEKLKKIDRIPERDKLKD-----EPKIKLLKKPEKGDEKELDKREKAKK 290
EE K +D L+ ++LK+ + K++L++ + E +L+ +E +K
Sbjct: 193 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS--EIQLNVKELKRK 250
Query: 291 LDKENL--SDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR 348
L++ L ++ ++ L K S + + E+E +++ E QE ++
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 349 ERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI--GSSEKT 406
E E +++EE+ R E+E+ + +EE+M+++++ + +K +K E + EK
Sbjct: 311 EWEEKIQEQEEKIR-----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 407 EKKEEVV--KRDRIR 419
+ EE++ K ++IR
Sbjct: 366 RRLEEMMWEKEEKIR 380
Score = 46.2 bits (108), Expect = 6e-05
Identities = 33/147 (22%), Positives = 75/147 (51%), Gaps = 3/147 (2%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K R+ + + + + R+ E EKM E + E+ + + +E ++
Sbjct: 516 EKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575
Query: 197 TTPLLSFLKNKQRMREEK--REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKID 254
+ K K R +EEK +E + RE E Q E+E + W++EEK ++ + ++ +
Sbjct: 576 QEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQ-EQEEKMWEQEEKMCEQEEKMQEQEE 634
Query: 255 RIPERDKLKDEPKIKLLKKPEKGDEKE 281
++ +++ E +++L ++ EK E +
Sbjct: 635 KMRRQEEKMWEQEVRLRQQEEKMQEHQ 661
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 96.3 bits (238), Expect = 5e-20
Identities = 86/346 (24%), Positives = 180/346 (52%), Gaps = 23/346 (6%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+++ K RD + + D R+ E + EKM E + EE + + +E KKT
Sbjct: 387 EQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQVEKMREEKKMQEQE---KKTRDQ 442
Query: 201 LSFLKNKQRMREEKR----EERRRREIERKRQREEERRKWKEEEK-----RKRKDIEKLK 251
++ ++R+RE ++ EE RE E K Q++EE W++EEK R + EKL
Sbjct: 443 EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM-WEQEEKEWQQQRLPEQKEKLW 501
Query: 252 KIDRIPERDKLKDEPKIKLLKKPEK-GDEKELDKREKAKKLDKENLSDERASGQSCTLPK 310
+ +++ E+++ E + K+ + E G EK++ ++EK + ++E+ E+ K
Sbjct: 502 EQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMR--EQEDQMWEQEEKMRDQEQK 559
Query: 311 RSDSELKDEKPKRPEDESGRDYREREREYE--RDQERILRERERLKRQEEERRRQKER-- 366
D E + EK + +++ D E+ RE E R++E+ +RE E + R++EE+ +++E
Sbjct: 560 MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 619
Query: 367 YEKEKTFKRKEEEMKKEKDTLRDKGKKA-ESTESIGSSEK-TEKKEEVVKRDRIRNKDRP 424
E+E+ +EE+M+++++ + ++ +K E E + ++ E+KE++ + ++++ +++
Sbjct: 620 QEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKM 679
Query: 425 AMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
Q + + + + K+ D R++ES K+ EE
Sbjct: 680 QEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREE 725
Score = 83.6 bits (205), Expect = 4e-16
Identities = 68/283 (24%), Positives = 148/283 (52%), Gaps = 20/283 (7%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMT-STPETLLEEIEAKNRELIAKKTTP 199
+++ K RD + D + +E + EK T E + EE + RE ++
Sbjct: 548 EQEEKMRDQEQKMWDQEER----MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEE 603
Query: 200 LLSFLKNKQRMREEKREERRRREIERK-RQREEERRKWKEEEKRKRKDIEKLKKIDRIPE 258
++ + K + +EEK +E+ + E++ + +E+E + W++EEK ++ EK+ + R+PE
Sbjct: 604 MMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-EKMWEQQRLPE 662
Query: 259 -RDKLKDEPKIKLLKKPEKGDEK--ELDKREKAKKLDKENLSDERASGQSCTLPKRSDSE 315
++KL + K++ +K ++ +EK E +K EK + ++ D+ + ++ +R
Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKM 722
Query: 316 LKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEE---ERRRQKERYEK--E 370
++E+ R ++E +E+E + + +E + + E++ QEE E++R E+ EK E
Sbjct: 723 REEEEMMREQEEK---MQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWE 779
Query: 371 KTFKRKEEEMKKEKDTLRDKGKKAESTES--IGSSEKTEKKEE 411
+++E++ ++++ +RD+ +K E G EK +EE
Sbjct: 780 HEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 82.4 bits (202), Expect = 8e-16
Identities = 70/306 (22%), Positives = 155/306 (50%), Gaps = 30/306 (9%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRM--REEKREERRRR----EIERKRQREE---ER 233
EE++ KN EL K PL K++ ++ +E KR+ R + +++ +EE +
Sbjct: 221 EELKKKNAELQEK--LPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQE 278
Query: 234 RKWKEEEKRKRKDIEKL-KKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD 292
+ +E+EK+ RK EK+ ++ +R+ E++ E + K+ ++ EK L ++EK +
Sbjct: 279 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ-----EKRLREQEKELREQ 333
Query: 293 KENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYE------------ 340
++ L +++ + + + ++ +++ K E E + +R+ ER +E
Sbjct: 334 EKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE-KMWRQEERLWEQEKQMREQEQKM 392
Query: 341 RDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI 400
RDQE + E++ R++EER R++E+ ++ R+E++M++++ RD+ +K + E I
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERI 452
Query: 401 GSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESG 460
EK ++EE R++ + +++ + + P+ K + ++QE
Sbjct: 453 REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Query: 461 ISHRKE 466
I ++E
Sbjct: 513 IWEQEE 518
Score = 82.0 bits (201), Expect = 1e-15
Identities = 61/314 (19%), Positives = 162/314 (51%), Gaps = 33/314 (10%)
Query: 141 KKKTKKRDTKV-----------GTIDDDPEYRKFLESYATDNEK-MTSTPETLLEEIEAK 188
+KK +K++ K+ G + + E E + EK + + L E+ E +
Sbjct: 285 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELR 344
Query: 189 NRELIAKKTTPLLSFLKNKQRMREEK---------REERRRREIERKRQREEERRKWKEE 239
+E ++ + + K R +EEK +E++ RE E+K R++E R W+++
Sbjct: 345 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK-MRDQEERMWEQD 403
Query: 240 EKRKRKDIEKLKKIDRIPER-DKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSD 298
E+ + K+ E++++ +++ E+ +K+++E K++ +K + E+++ + E+ ++ +K+ +
Sbjct: 404 ERLREKE-ERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 299 ERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYER---------DQERILRE 349
E + ++ + + +++ K + + + +E+ E E+ +QE +R+
Sbjct: 463 EETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD 522
Query: 350 RERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKK 409
+E + QE++ RQ++ E+E +EE+M+ ++ + D+ ++ E + +++
Sbjct: 523 QEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQE 582
Query: 410 EEVVKRDRIRNKDR 423
E++ + +R+R +++
Sbjct: 583 EKMREEERMREREK 596
Score = 81.6 bits (200), Expect = 1e-15
Identities = 52/213 (24%), Positives = 121/213 (56%), Gaps = 10/213 (4%)
Query: 212 EEKREERRRREIERKRQREEE-----RRKWKEEEKRKRKDIEKL-KKIDRIPERDKLKDE 265
E+ REE R RE E+K + EEE K +E+E++ ++ EK+ ++ +++ E+++ E
Sbjct: 583 EKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWE 642
Query: 266 PKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPE 325
+ K+ ++ EK E++ +K K + E + ++ + K + E ++K + E
Sbjct: 643 QEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQ--EEKIWEQEKMEKKTQEQE 700
Query: 326 DESGRDYREREREYERDQERILRERERLKRQEEERRRQKER--YEKEKTFKRKEEEMKKE 383
++ + RE E R++E+ +RE E + R++EE+ +++E E+E+ +EE+M ++
Sbjct: 701 KKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQ 760
Query: 384 KDTLRDKGKKAESTESIGSSEKTEKKEEVVKRD 416
++ + ++ + E E + EK +++E++ +++
Sbjct: 761 EEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Score = 73.6 bits (179), Expect = 4e-13
Identities = 67/303 (22%), Positives = 150/303 (49%), Gaps = 32/303 (10%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFL----ESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+KKT+ ++ K+ + E K + E+ EKM E + E+ E + ++ +
Sbjct: 436 EKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPE 495
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDI--------- 247
L + + K + +EEK E+ + +++ +E++ W++E+ R+++D
Sbjct: 496 QKEKL-WEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMR 554
Query: 248 -EKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKE-LDKREKAKKLDKENLSDERASGQS 305
++ K D+ +K E + K + EK E+E + +REK + ++E + ++ Q
Sbjct: 555 DQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE 614
Query: 306 CTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD-----QERILRERERL----KRQ 356
+ E E+ ++ +++ + + + E+ +E++ Q+R+ ++E+L K Q
Sbjct: 615 QEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQ 674
Query: 357 EEERRRQKER--YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVK 414
E+E+ +++E +E+EK K+ +E+ KK D +K ES+ EK ++EE +
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ-----EKMREEESMREREKKMREEEEMM 729
Query: 415 RDR 417
R++
Sbjct: 730 REQ 732
Score = 72.4 bits (176), Expect = 8e-13
Identities = 61/290 (21%), Positives = 140/290 (48%), Gaps = 12/290 (4%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ R+ + + + + ++ E EKM E + E+ E +
Sbjct: 596 KKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMW 655
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
L K K E+ +E+ + +E E K +E+ K +E+++K D EK+++ + +
Sbjct: 656 EQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKL---DKENLSDERASGQSCTLPKRSD 313
ER+K E + + ++ EK E+E +E+ +++ +++ E + LP++ +
Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKE 775
Query: 314 SELKDEKPKRPED--ESGRDYREREREYERDQERILRERERLKRQEEERRRQKERY--EK 369
+ EK + E E R++E + +E++ + E+++ QEE+ Q+E+ ++
Sbjct: 776 KLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQE 835
Query: 370 EKTFKRKE-----EEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVK 414
EK + ++E EE +EK +++ + + + G EK ++EE ++
Sbjct: 836 EKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMR 885
Score = 69.3 bits (168), Expect = 7e-12
Identities = 58/223 (26%), Positives = 113/223 (50%), Gaps = 18/223 (8%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKR----EERRRREIER 225
+ EKM E + E+ + + + +K T ++ ++ MRE ++ EE RE E
Sbjct: 675 EQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEE 734
Query: 226 KRQREEERRK------WKEEEKRKRKDIEKLKKIDRIPE-RDKLKDEPKIKLLKKPEKGD 278
K Q +EE+ + W++EEK ++ EK+ + R+PE ++KL + K++ +K + +
Sbjct: 735 KMQEQEEKMQEQEEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 279 EKELDKREKAK-KLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER 337
EK D+ EK + + +K +E+ GQ + + + E+ ++E E+
Sbjct: 794 EKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKME 853
Query: 338 EYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEM 380
E + QE +RE+E R +EE+ R E+E+ + +EE++
Sbjct: 854 EKMQGQEEKMREQEEKMRGQEEKMR-----EQEEKMRGQEEKI 891
Score = 67.8 bits (164), Expect = 2e-11
Identities = 61/252 (24%), Positives = 133/252 (52%), Gaps = 22/252 (8%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEK--REERRRREIERKR 227
+ EKM E + E+ E K R+ + + K R +E++ +E + R+ E+K
Sbjct: 502 EQEKMQEQEEKIWEQ-EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 560
Query: 228 QREEER--RKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKR 285
+EER +K +E+EK+ EK+++ +R+ ER+K E + + ++ EK E+E +
Sbjct: 561 WDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQ 620
Query: 286 EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQER 345
E+ +K+ ++ +E+ Q + ++ + ++ +++ K E + + +E+ E+E+ QE+
Sbjct: 621 EQEEKMWEQ---EEKMQEQEEKMWEQEE-KMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQ 676
Query: 346 ILRERERLKRQEEERR----RQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI- 400
K QE+E + + E+ +E+ K ++E +E++++R++ KK E +
Sbjct: 677 E-------KMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM 729
Query: 401 -GSSEKTEKKEE 411
EK +++EE
Sbjct: 730 REQEEKMQEQEE 741
Score = 67.0 bits (162), Expect = 3e-11
Identities = 60/225 (26%), Positives = 115/225 (51%), Gaps = 22/225 (9%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEK----REERRRREIER 225
++EKM + +E + +E + KKT ++++MREE+ RE++ R E E
Sbjct: 669 EHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEM 728
Query: 226 KRQREE----ERRK--------WKEEEKRKRKDIEKLKKIDRIPE-RDKLKDEPKIKLLK 272
R++EE + K W++EEK ++ EK+ + R+PE ++KL + K++ +
Sbjct: 729 MREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQE 787
Query: 273 KPEKGDEKELDKREKAK-KLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD 331
K + +EK D+ EK + + +K +E+ GQ + + + E+ ++E
Sbjct: 788 KIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWG 847
Query: 332 YREREREYERDQERILRERERLKRQEEERRRQKE---RYEKEKTF 373
E+ E + QE +RE+E R +EE+ R++E R ++EK +
Sbjct: 848 QEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEKIY 892
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 96.3 bits (238), Expect = 5e-20
Identities = 67/220 (30%), Positives = 125/220 (56%), Gaps = 14/220 (6%)
Query: 202 SFLKNKQRMREEKREERRRREIERKRQREE-ERRKWKEEEKRKRKDIEKLKKIDRIPERD 260
S ++ ++R E ++E ++ RE ERK++R E E+RK + E++RKR+ +K KK +R E
Sbjct: 36 SEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE- 94
Query: 261 KLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE---RASGQSCTLPKRSDSELK 317
++ K + K+ ++G+EKE KR+K +K ++ S E R + +R + E K
Sbjct: 95 --RERKKRRREKENKEGEEKE--KRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 318 DEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKE 377
E+ ++ + R RER++ E+++ER +E+ER +R++ ER R++ + E+E+ +R
Sbjct: 151 KEEREKERERKERKKRERKQVGEKEEER--KEKERKERKKRERNRKERKKERERKERR-- 206
Query: 378 EEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDR 417
E KKE+ ++ K+ + EK K E +R +
Sbjct: 207 -ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 94.4 bits (233), Expect = 2e-19
Identities = 62/217 (28%), Positives = 115/217 (52%), Gaps = 33/217 (15%)
Query: 207 KQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEP 266
+ +RE +RE R+E K++RE ER+K + E ++++++ EK +K +R
Sbjct: 35 QSEIREREREIETRKE--GKKERESERKKERREREKRKREREKERKRERG---------- 82
Query: 267 KIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPED 326
KK +KG+ K+ ++ K ++ +KEN E + E + +K K+
Sbjct: 83 -----KKEKKGERKKEERERKKRRREKENKEGE-------------EKEKRKKKEKKERG 124
Query: 327 ESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDT 386
+ ++ +ERER+ ER +E +ERER K + E+ R +KER ++E+ ++EE +KEK+
Sbjct: 125 RTSKEGKERERKEERKREE-RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE- 182
Query: 387 LRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
R + KK E E+ K+ K++R + ++R
Sbjct: 183 -RKERKKRERNRKERKKERERKERRERKKERKKKEER 218
Score = 81.6 bits (200), Expect = 1e-15
Identities = 61/214 (28%), Positives = 118/214 (55%), Gaps = 23/214 (10%)
Query: 184 EIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRK 243
EI + RE+ +K K+R E K+E R R + +R+R++E +R + K+E+K +
Sbjct: 37 EIREREREIETRKEG-------KKERESERKKERREREKRKREREKERKRERGKKEKKGE 89
Query: 244 RKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEK--------GDEKEL-DKREKAKKLDKE 294
RK E+ +K R E++ + E K K KK +K G E+E ++R++ ++ ++E
Sbjct: 90 RKKEERERK-KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERE 148
Query: 295 NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREY-ERDQERILRERERL 353
+ER + K+ + + EK + +++ ++ ++RER ER +ER +ER
Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKER--ERKERR 206
Query: 354 KRQEEERR---RQKERYEKEKTFKRKEEEMKKEK 384
+R++E ++ R+KER + +T R++E K+E+
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRER 240
Score = 70.5 bits (171), Expect = 3e-12
Identities = 59/204 (28%), Positives = 102/204 (50%), Gaps = 21/204 (10%)
Query: 271 LKKP--EKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDES 328
+ KP + G + E+ +RE+ + KE K +SE K E+ +R E
Sbjct: 25 ISKPCTQPGWQSEIREREREIETRKEG-------------KKERESERKKERRER---EK 68
Query: 329 GRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLR 388
+ RE+ER+ ER ++ ER++ +R+ ++RRR+KE E E+ KRK++E KKE+
Sbjct: 69 RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKE-KKERGRTS 127
Query: 389 DKGKKAESTESIGSSEKTEKKEEVVKRDRIR-NKDRPAMQLYQPGARSRNRLCPPDDSTK 447
+GK+ E E E+ E++ + +R++ R K+R + Q G + R K
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERK 187
Query: 448 SGD-SAAERKQESGISHRKEGGEE 470
+ + ERK+E R+E +E
Sbjct: 188 KRERNRKERKKERERKERRERKKE 211
Score = 68.2 bits (165), Expect = 2e-11
Identities = 56/226 (24%), Positives = 105/226 (46%), Gaps = 47/226 (20%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K+R + G + E +K + E+ E +E E K + +K
Sbjct: 67 EKRKREREKERKRERGKKEKKGERKK------EERERKKRRREKENKEGEEKEKRKKKEK 120
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
+ + K+R R+E+R+ R+E ERK++ E+ R+ KE +KR+RK +
Sbjct: 121 KERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG-------- 172
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSEL 316
+K E+ EKE +R+K ++ KE + R E
Sbjct: 173 ---------------EKEEERKEKERKERKKRERNRKERKKE------------RERKER 205
Query: 317 KDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRR 362
++ K +R + E ER++E ++D++ RE+ER KR+ +ER++
Sbjct: 206 RERKKERKKKE------ERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 94.4 bits (233), Expect = 2e-19
Identities = 77/339 (22%), Positives = 175/339 (51%), Gaps = 30/339 (8%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+K+ K R + + + + R+ E EKM E + E+ E K REL K
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEK-EEKIRELEEKMHEQE 404
Query: 201 LSFLKNKQRMREEK-REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPER 259
+ ++R EEK RE+ +R+E E K R+EE+ + ++EEK + ++ + ++ ++I E+
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIR-EQEEKIREQEKKMWRQEEKIHEQ 463
Query: 260 DKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDE 319
+K+++E K + ++ + +EK ++ E ++ +K + +E+ + K+ + + E
Sbjct: 464 EKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEK-------IRKQEEKVWRQE 516
Query: 320 KPKRPEDESGRDYRE---REREYERDQERILRERERLKRQ----EEERRRQKE--RYEKE 370
+ R ++E R+ E R+ E R+QE + RE E++ Q EEE+R+++E + +E
Sbjct: 517 EKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 371 KTFKRKEEEMKKEKDTLRDKGKKAESTES---------IGSSEKTEKKEEVVK--RDRIR 419
+ + +EE++ ++++ +R++ +K + E EK +++EE ++ ++IR
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 420 NKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
++ + + ++C ++ + + R++E
Sbjct: 637 EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEE 675
Score = 84.0 bits (206), Expect = 3e-16
Identities = 69/323 (21%), Positives = 160/323 (49%), Gaps = 17/323 (5%)
Query: 164 LESYATDNE---KMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRR 220
L++ +NE ++ E + E K +E K + ++++RE++ + RR+
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQ 340
Query: 221 REI---ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKG 277
E+ + ++ R +E W++EEK +R++ +K +++ ++++ E + K+ + EK
Sbjct: 341 EEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 400
Query: 278 DEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER 337
E+E + ++ K+ ++E + ++ + R + ++++++ K E E + +R+ E+
Sbjct: 401 HEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEK-KMWRQEEK 459
Query: 338 EYERD---QERILRERERLKRQEEERRRQKERY-EKEKTFKRKEEEMKKEKDTLRDKGKK 393
+E++ +E +E+E + RQEE+ Q+E + +KEK +++E+ K+E+ R + K
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519
Query: 394 AESTESI-GSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSA 452
E E I EK ++EE ++ ++ M + R D + +
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579
Query: 453 AER-----KQESGISHRKEGGEE 470
E+ +QE I ++E +E
Sbjct: 580 REQEEKVWRQEEKIREQEEKRQE 602
Score = 84.0 bits (206), Expect = 3e-16
Identities = 63/251 (25%), Positives = 137/251 (54%), Gaps = 12/251 (4%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
++K +K++ KV ++ + R+ E EKM E + E+ E E + +
Sbjct: 502 EEKIRKQEEKVWRQEE--KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERD 260
K +++ + R+E + RE E K R+EE+ + ++EEKR+ ++ + K+ ++I E++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIR-EQEEKRQEQEEKMWKQEEKIREQE 618
Query: 261 KLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLS----DERASGQSCTLPKRSDSEL 316
+ E + K+ ++ EK E+E +E+ +K+ ++ +E+ Q T+ ++ +
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 317 KDEKPKRPEDESGRDYREREREYER----DQERILRERERLKRQEEERRRQKER-YEKEK 371
+ EK R ++E R+ E +E E +E++ + E+++ QEE+ RRQ+E+ +E+E
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 372 TFKRKEEEMKK 382
+++EE+M++
Sbjct: 739 RLRQQEEKMQE 749
Score = 84.0 bits (206), Expect = 3e-16
Identities = 61/253 (24%), Positives = 140/253 (55%), Gaps = 12/253 (4%)
Query: 165 ESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIE 224
E EK+ E + E+ E K RE K + ++ REE++ + + E
Sbjct: 503 EKIRKQEEKVWRQEEKIREQ-EEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWE 561
Query: 225 RKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK 284
++++E+E + W++EEK + ++ + ++ ++I E+++ + E + K+ K+ EK E+E
Sbjct: 562 EEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKI 621
Query: 285 REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE----REREYE 340
+E+ +K+ ++ +E+ Q + + + ++ +++ K E E +E R+ E
Sbjct: 622 QEQEEKIREQ---EEKIREQE-EMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKI 677
Query: 341 RDQERILRERE-RLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTE 398
R+QE+ +RE+E +++ QEE + Q+E+ +E+E+ +EE+M+++++ +R + +K E
Sbjct: 678 REQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737
Query: 399 SIGSSEKTEKKEE 411
+ ++ EK +E
Sbjct: 738 -VRLRQQEEKMQE 749
Score = 81.3 bits (199), Expect = 2e-15
Identities = 68/298 (22%), Positives = 149/298 (50%), Gaps = 20/298 (6%)
Query: 179 ETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRR--REIERKRQREE---ER 233
E + E E K RE K + ++ EEKR+E+ R+ E+ ++EE ++
Sbjct: 436 EEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQK 495
Query: 234 RKWKEEEKRKRKDIEKL-KKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD 292
K E+E++ RK EK+ ++ ++I E+++ E + K+ ++ EK E+E RE+ K +
Sbjct: 496 EKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHE 555
Query: 293 KENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERER 352
+E + +E + R + ++++++ K E RE+E + + +E++ ++ E+
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE--KIREQEEKRQEQEEKMWKQEEK 613
Query: 353 LKRQEEERRRQKE--RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKT---- 406
++ QEE+ + Q+E R ++EK +++E ++E+ + K E E + E+T
Sbjct: 614 IREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQ 673
Query: 407 -EKKEEVVKR-----DRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
EK E K+ ++IR ++ + + ++C ++ + + R++E
Sbjct: 674 EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 731
Score = 79.0 bits (193), Expect = 9e-15
Identities = 71/276 (25%), Positives = 147/276 (53%), Gaps = 31/276 (11%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQ--- 228
+++ + + L +E+++ + +L A+ L N+Q+ + R+E + +E E K Q
Sbjct: 261 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 320
Query: 229 ---REEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKE---- 281
RE+E + ++EEK +R++ +K +++ ++++ E + K+ ++ E EKE
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 282 ------LDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRER 335
+K EK ++L+++ E+ Q KR + E E+ KR E E+ R
Sbjct: 381 RQEEMMWEKEEKIRELEEKMHEQEKIREQE---EKRQEEEKIREQEKRQEQEA---KMWR 434
Query: 336 EREYERDQERILRERE-RLKRQEE-----ERRRQKERYEKEKTFKRKEEEMKKEKDTLRD 389
+ E R+QE +RE+E ++ RQEE E+ R++E+ ++++ R+EE++ ++++ R
Sbjct: 435 QEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ 494
Query: 390 KGKKAESTESI-GSSEKTEKKEEVVK--RDRIRNKD 422
K K E E I EK ++EE ++ ++IR ++
Sbjct: 495 KEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530
Score = 49.7 bits (117), Expect = 6e-06
Identities = 73/366 (19%), Positives = 165/366 (45%), Gaps = 43/366 (11%)
Query: 135 PFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTP--ETLLEEIEAKN--- 189
P A TKK+ GT +PE ++ ++E+ S E L E+EA+
Sbjct: 76 PSVGTAASDTKKKKINNGT---NPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTI 132
Query: 190 RELIAKKTTPLLSFLKNKQRMREEKREERR-----------RREIERKRQREEERRKWKE 238
R L +KT ++ ++ +++ + E R E+E+ ++K +
Sbjct: 133 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 192
Query: 239 ---EEKRKRKDIEKLKKIDRIPERDKLKD-----EPKIKLLKKPEKGDEKELDKREKAKK 290
EE K +D L+ ++LK+ + K++L++ + E +L+ +E +K
Sbjct: 193 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS--EIQLNVKELKRK 250
Query: 291 LDKENL--SDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR 348
L++ L ++ ++ L K S + + E+E +++ E QE ++
Sbjct: 251 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 310
Query: 349 ERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI--GSSEKT 406
E E +++EE+ R E+E+ + +EE+M+++++ + +K +K E + EK
Sbjct: 311 EWEEKIQEQEEKIR-----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 407 EKKEEVV--KRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHR 464
++EE++ K +++R ++ +++ + R + K + +R++E I +
Sbjct: 366 RRQEEMMWEKEEKMRRQEE---MMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 465 KEGGEE 470
++ E+
Sbjct: 423 EKRQEQ 428
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 93.2 bits (230), Expect = 5e-19
Identities = 75/338 (22%), Positives = 171/338 (50%), Gaps = 31/338 (9%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K R+ + + + + R+ E EKM E + E+ E R+
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ----- 429
Query: 197 TTPLLSFLKNKQRMREEKREERRR-REIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
++ + K R EEK E+ + RE E KRQ EE K +E+EKR+ ++ + ++ ++
Sbjct: 430 -EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE---KIREQEKRQEQEAKMWRQEEK 485
Query: 256 IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENL--SDERASGQSCTLPKRSD 313
I E+++ E + K+ ++ EK E+E RE+ K+ ++E + +E+ Q ++
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQE-KIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Query: 314 SELKDEKPKRPEDESGRD---YREREREYERDQERILRERERLKRQEEERRRQKERY-EK 369
++EK ++ E++ R ++E + +E++ R+ E+++ QEE+ R Q+E+ E+
Sbjct: 545 IHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQ 604
Query: 370 EKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVK---------RDRIRN 420
E+ + +EE+M ++++ + ++ +K + E EK ++EE ++ ++IR
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQE-----EKMRRQEEKIREQEKKIREQEEKIRE 659
Query: 421 KDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
++ + + ++C ++ + + R++E
Sbjct: 660 QEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Score = 92.0 bits (227), Expect = 1e-18
Identities = 58/292 (19%), Positives = 152/292 (52%), Gaps = 15/292 (5%)
Query: 181 LLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE 240
L + + E + ++ + + + Q E+ RE+ + + ++ R +E W++EE
Sbjct: 351 LWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEE 410
Query: 241 KRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDER 300
K +R++ +K +++ ++++ E + K+ + EK E+E + ++ K+ ++E + ++
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 470
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD---QERILRERERLKRQE 357
+ R + ++++++ K E E + +R+ E+ +E++ +E +E+E + RQE
Sbjct: 471 KRQEQEAKMWRQEEKIREQEEKIREQEE-KMWRQEEKIHEQEKIREEEKRQEQEEMWRQE 529
Query: 358 EERR------RQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTES--IGSSEKTEK 408
E+ R RQKE+ +E+E+ +++EE+M ++++ + D+ +K E EK +
Sbjct: 530 EKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIRE 589
Query: 409 KEEVVK--RDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
+EE ++ ++IR ++ + + ++C ++ + + R++E
Sbjct: 590 QEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641
Score = 74.7 bits (182), Expect = 2e-13
Identities = 52/229 (22%), Positives = 126/229 (55%), Gaps = 34/229 (14%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIER---- 225
+ EK E +E + + +E I ++ + ++Q + K+EE+ R+ E+
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKI-----HEQEEKIRKQEEKMWRQEEKMHDQ 569
Query: 226 -KRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDK 284
++ RE+E + W++EEK + ++ + ++ ++I E++++ E + K+ ++ EK E+E
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKM 629
Query: 285 REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPK-RPEDESGRDYREREREYE--- 340
+E+ +K+ +R + ++++++ K R ++E R+ E +E E
Sbjct: 630 QEQEEKM------------------RRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKM 671
Query: 341 -RDQERILRERERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTL 387
+E++ + E+++ QEE+ RRQ+E+ +E+E +++EE+M++ ++ L
Sbjct: 672 WEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHL 720
Score = 72.0 bits (175), Expect = 1e-12
Identities = 58/264 (21%), Positives = 134/264 (50%), Gaps = 7/264 (2%)
Query: 154 IDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREE 213
I + E R+ E ++ + +E + + +E ++ + + K +E+
Sbjct: 453 IREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEK 512
Query: 214 KREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKK 273
REE +R+E E ++EE+ R+ +E ++K K E+ +KI + E+ ++E +K
Sbjct: 513 IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEK 572
Query: 274 PEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYR 333
+ +EK + EK ++ +++ E + + + + ++ +++ K E E +
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQ 632
Query: 334 E----REREYERDQERILRERERLKRQEEERRRQKER--YEKEKTFKRKEEEMKKEKDTL 387
E R+ E R+QE+ +RE+E R++EE +++E +E+E+ +EE+M+++++ +
Sbjct: 633 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 692
Query: 388 RDKGKKAESTESIGSSEKTEKKEE 411
R + +K E + ++ EK +E
Sbjct: 693 RRQEEKMWEQE-VRLRQQEEKMQE 715
Score = 48.5 bits (114), Expect = 1e-05
Identities = 68/315 (21%), Positives = 144/315 (45%), Gaps = 40/315 (12%)
Query: 135 PFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTP--ETLLEEIEAKN--- 189
P A TKK+ GT +PE ++ ++E+ S E L E+EA+
Sbjct: 137 PSVGTAASDTKKKKINNGT---NPETTTSGGCHSPEDEQKASHQHQEALRRELEAQVHTI 193
Query: 190 RELIAKKTTPLLSFLKNKQRMREEKREERR-----------RREIERKRQREEERRKWKE 238
R L +KT ++ ++ +++ + E R E+E+ ++K +
Sbjct: 194 RILTCQKTELQMALYYSQHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKAD 253
Query: 239 ---EEKRKRKDIEKLKKIDRIPERDKLKD-----EPKIKLLKKPEKGDEKELDKREKAKK 290
EE K +D L+ ++LK+ + K++L++ + E +L+ +E +K
Sbjct: 254 RYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKS--EIQLNVKELKRK 311
Query: 291 LDKENL--SDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR 348
L++ L ++ ++ L K S + + E+E +++ E QE ++
Sbjct: 312 LERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQ 371
Query: 349 ERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI--GSSEKT 406
E E +++EE+ R E+E+ + +EE+M+++++ + +K +K E + EK
Sbjct: 372 EWEEKIQEQEEKIR-----EQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 426
Query: 407 EKKEEVV--KRDRIR 419
++EE++ K ++IR
Sbjct: 427 RRQEEMMWEKEEKIR 441
Score = 40.8 bits (94), Expect = 0.003
Identities = 37/158 (23%), Positives = 79/158 (50%), Gaps = 17/158 (10%)
Query: 141 KKKTKKRDTKVGT----IDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
++K ++++ KV I + E + E + E+MT E + E E K E K
Sbjct: 570 EEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK- 628
Query: 197 TTPLLSFLKNKQRMREEK-REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
+ + K R +EEK RE+ ++ + ++ RE+E ++EEK ++ ++
Sbjct: 629 ----MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQE-------EK 677
Query: 256 IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDK 293
+ E+++ E + K+ ++ EK E+E+ R++ +K+ +
Sbjct: 678 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715
>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
Length = 290
Score = 92.8 bits (229), Expect = 6e-19
Identities = 70/224 (31%), Positives = 126/224 (56%), Gaps = 23/224 (10%)
Query: 206 NKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDE 265
++QR R+ RE + +E +R R+R+ ERR+ KE+E + +D EK +I+R ER+K K
Sbjct: 76 DRQRERDRVRE-KTEKERDRDRKRDRERRR-KEKETNRNRDREKQTEIERDREREKQKGR 133
Query: 266 PKIKLLKKPEKGDEKELDK-REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRP 324
+ + ++G E+E D+ REK ++E +++ GQ T +R + + + EK K
Sbjct: 134 ERER-----DRGRERERDRDREK----ERERQTEKDRDGQRETETER-ERDREREKQKER 183
Query: 325 EDESGRDYR---EREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMK 381
E E RD + E+ERE + D RER+R ++ + ER+R+ +R + +T +R+E +
Sbjct: 184 ETERDRDRQRDTEKERERQTD-----RERDRQRKTQTERQRETDREGERETDRRRERQRD 238
Query: 382 KE--KDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
++ K+ R++ +K E + K E+KE+ + R +K R
Sbjct: 239 RDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKR 282
Score = 85.1 bits (209), Expect = 1e-16
Identities = 64/215 (29%), Positives = 111/215 (51%), Gaps = 19/215 (8%)
Query: 188 KNRELIAKKTTPLLSFLKNKQRMREEKREERRRR---EIERKRQREEERRKWKEEEKRKR 244
+ R+ + +KT K+R R+ KR+ RRR E R R RE++ ++ E+ K+
Sbjct: 79 RERDRVREKT--------EKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDREREKQ 130
Query: 245 KDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGD-----EKELDKREKAKKLDKENLSDE 299
K E+ + R ERD+ +++ + + +K G E+E D RE+ K+ ++E D
Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERD-REREKQKERETERDR 189
Query: 300 RASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEE 359
+ +R +D + K + RE ERE +R +ER R+R+R K ++ E
Sbjct: 190 DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRER-QRDRDRGKERDRE 248
Query: 360 RRRQKERYEKEKTFKRKE-EEMKKEKDTLRDKGKK 393
R R++ER ++ K ++KE +E KKE+ DK +K
Sbjct: 249 RDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283
Score = 67.4 bits (163), Expect = 3e-11
Identities = 60/207 (28%), Positives = 101/207 (48%), Gaps = 19/207 (9%)
Query: 273 KPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDY 332
K GD+++ ++ +K +KE D + + +R + E + + + E RD
Sbjct: 70 KDADGDDRQRERDRVREKTEKERDRDRKRDRER----RRKEKETNRNRDREKQTEIERD- 124
Query: 333 REREREYERDQERIL-RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKG 391
RERE++ R++ER RERER + +E+ER RQ EK++ +R E E ++E+D R+K
Sbjct: 125 REREKQKGRERERDRGRERERDRDREKERERQT---EKDRDGQR-ETETERERDREREKQ 180
Query: 392 KKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAM-----QLYQPGARSRNRLCPPD--- 443
K+ E+ TEK+ E + DR R++ R + + G R +R
Sbjct: 181 KERETERDRDRQRDTEKERE-RQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239
Query: 444 DSTKSGDSAAERKQESGISHRKEGGEE 470
D K D +RK+E +KE +E
Sbjct: 240 DRGKERDRERDRKEERKKERKKERKKE 266
Score = 49.3 bits (116), Expect = 8e-06
Identities = 45/173 (26%), Positives = 82/173 (47%), Gaps = 8/173 (4%)
Query: 122 NKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETL 181
N+ ++ E ++ K+K ++R+ G + R+ T+ ++ ET
Sbjct: 110 NRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDR-DGQRETE 168
Query: 182 LEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREER--RRREIERKRQREEERRKWKEE 239
E + RE ++ T +++QR E++RE + R R+ +RK Q E +R +E
Sbjct: 169 TERERDREREKQKERETERD---RDRQRDTEKERERQTDRERDRQRKTQTERQRETDREG 225
Query: 240 EKRKRKDIEKLKKIDRIPERDKLKD--EPKIKLLKKPEKGDEKELDKREKAKK 290
E+ + E+ + DR ERD+ +D E + K KK K + KE K EK ++
Sbjct: 226 ERETDRRRERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRRE 278
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/93 (25%), Positives = 53/93 (56%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
K ++R + +R+ +R+ + ER+R+ + E + + + +++D ++ K+ DR +R + +
Sbjct: 197 KERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256
Query: 265 EPKIKLLKKPEKGDEKELDKREKAKKLDKENLS 297
+ + K KK K +KE +RE K+ E +S
Sbjct: 257 KERKKERKKERKEKKKEEKRREDKKRKWGEGIS 289
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/100 (31%), Positives = 53/100 (53%), Gaps = 8/100 (8%)
Query: 327 ESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKR---KEEEMKKE 383
++ +D +R+ ERD+ R E+ER + +R+R +ER KEK R +E++ + E
Sbjct: 67 QAHKDADGDDRQRERDRVREKTEKER----DRDRKRDRERRRKEKETNRNRDREKQTEIE 122
Query: 384 KDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
+D R+K K E G + ++ E +R+R KDR
Sbjct: 123 RDREREKQKGRERERDRGRERERDRDRE-KERERQTEKDR 161
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 92.0 bits (227), Expect = 1e-18
Identities = 83/314 (26%), Positives = 145/314 (46%), Gaps = 72/314 (22%)
Query: 158 PEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREE 217
PE ++ E D + +S E NRE + ++P+ +N + R+E+REE
Sbjct: 603 PERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREE 662
Query: 218 RR---------------RREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKL 262
RR RE ER R+RE ER + ++ E+ K +++E+ + +R ER+K
Sbjct: 663 RRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKE 722
Query: 263 KDEPKIKLLKKPEKGDEKELDK-REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKP 321
+D E+ +++ D+ RE+ ++ D+E K+ +
Sbjct: 723 RDR---------ERDRDRDHDRERERERERDRE----------------------KERER 751
Query: 322 KRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMK 381
+R E E RERERE ER++ER RERER + +++ER RQ++ +K+ K +++ +
Sbjct: 752 EREERE-----RERERERERERER-ERERERARERDKERERQRDWEDKD---KGRDDRRE 802
Query: 382 KEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCP 441
K ++ D+ + G E+ KK R RN+ P+ + + R P
Sbjct: 803 KREEIREDRNPRD------GHDERKSKK-------RYRNEGSPSP---RQSPKRRREHSP 846
Query: 442 PDDSTKSGDSAAER 455
D+ SGD E+
Sbjct: 847 DSDAYNSGDDKNEK 860
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/281 (24%), Positives = 121/281 (43%), Gaps = 44/281 (15%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEER---RKWKEEEKRKRKDIEKLKKI--DRIPE- 258
+ ++R RE +RE R RE ER R+R++ER R W++++K + EK ++I DR P
Sbjct: 756 RERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Query: 259 -----------RDKLKDEPKIKLLKKPEKGDEKEL-----DKREKAKKLDKENLSDERAS 302
R++ P+ ++ E + + DK EK + L + E S
Sbjct: 816 GHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRS 875
Query: 303 GQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER-------EYERDQERILRERERLKR 355
L + K+E K ES R Y E+E + +R+Q IL E R++
Sbjct: 876 LSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEIL-ESSRMRA 934
Query: 356 QE----------EERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTE--SIGSS 403
Q+ E R + +K+ ++K + KKE D ++G ++E + S
Sbjct: 935 QDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSP 994
Query: 404 EKTEKKEEVVKRDRIRNKDRPAM--QLYQPGARSRNRLCPP 442
+K +KK+ + K+ + D + Q + R PP
Sbjct: 995 KKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPP 1035
Score = 57.8 bits (138), Expect = 2e-08
Identities = 70/316 (22%), Positives = 131/316 (41%), Gaps = 55/316 (17%)
Query: 204 LKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPE----- 258
L++ + MR+ + R+ + R + R + R R+ + +K D PE
Sbjct: 470 LRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSY 529
Query: 259 -RDKLKDEP---KIKLLKKPEKGDEKELDKR-----------EKAKKLDKENLSDERASG 303
R+ L++E +I+ + E E D+ EK + + + D +S
Sbjct: 530 GRNHLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSN 589
Query: 304 QSC--TLPKRSDSELKDEKPKRPEDESGRD------YRERER------------------ 337
+ + RS +D P+R + RD + ER+R
Sbjct: 590 SNYHDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQG 649
Query: 338 ---EYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKA 394
E ERD+ R R +R+ + +ER R+++R E+E+ + +E E ++E+D R+K ++
Sbjct: 650 RNDELERDERREERRVDRVDDRRDERARERDR-ERERD-RERERERERERDREREKEREL 707
Query: 395 ESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAE 454
E E E+ +KE +RDR R+ DR + + R R + + + + E
Sbjct: 708 E-RERAREREREREKERDRERDRDRDHDR---ERERERERDREKEREREREERERERERE 763
Query: 455 RKQESGISHRKEGGEE 470
R++E +E E
Sbjct: 764 RERERERERERERARE 779
Score = 42.7 bits (99), Expect = 7e-04
Identities = 71/320 (22%), Positives = 123/320 (38%), Gaps = 73/320 (22%)
Query: 139 AAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTT 198
+ + ++ D+ + DD ++ L S + D EK S T E K+R K+
Sbjct: 1203 SGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREKTKSLEITG----ERKSRIDQLKRGE 1258
Query: 199 PLLSFLKNKQRMRE------------------------EKREERRRREIERKRQREEERR 234
P S ++Q R ++ +ER R E +R+R+RE
Sbjct: 1259 PSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDT 1318
Query: 235 KWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKE 294
+ +E ++ KD + + DR+ ER++ E+E DKR + LD+E
Sbjct: 1319 RQREWDRDADKDWPRNRDRDRLRERER-----------------ERERDKR---RDLDRE 1358
Query: 295 NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLK 354
ER S + D + E + + R + E E+ERD E R+ L
Sbjct: 1359 R---ERLISDSVERDRDRDRDRTFESSQ--IESVKRCEAKLEGEHERDLESTSRDSLAL- 1412
Query: 355 RQEEERRRQKERYEKEKTFKRKEEEMKKEKDT----LRDKGKKAESTESIGSSE------ 404
KER +K+ + EE K + T D K + S+GS
Sbjct: 1413 --------DKERMDKDLGSVQGFEETNKSERTESLEAGDDESKLDDAHSLGSGAGEGYEP 1464
Query: 405 -KTEKKEEVVKRDRIRNKDR 423
++ +E++ D + +D+
Sbjct: 1465 ISDDELDEILAGDAEKREDQ 1484
Score = 42.4 bits (98), Expect = 0.001
Identities = 74/378 (19%), Positives = 142/378 (37%), Gaps = 57/378 (15%)
Query: 143 KTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTP--- 199
+T + D+ G I+ D + LE +K+ L +E K E+I KK
Sbjct: 145 ETNRDDSDNGDINYDYVHELSLEM---KRQKIQRELMKLEQENMEKREEIIIKKEVSPEV 201
Query: 200 LLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKE-----EEKRKRKDIEKLKKID 254
+ S L +R+ + +R+ + +++R+ +++R K + KK
Sbjct: 202 VRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQSKKKGP 261
Query: 255 RIPERD-----------KLKDEPKIK--LLKKPEKGDEKELDKREKAKKLDKENLSDERA 301
R P K K++ K+K + +K G ++ D + +K DK +
Sbjct: 262 RTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAG 321
Query: 302 SGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR------------- 348
S + S + + S R R Y+R LR
Sbjct: 322 QHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSS 381
Query: 349 -ERERLKRQEEERRRQKERYEKEKT-------FKRKEEEMKK---EKDTLRDKGKKAEST 397
+R++ + R+K R++ E+T +R+E+ K EKD+ ++ + + +
Sbjct: 382 PQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQS 441
Query: 398 ESIGSSEKTEKKEEVVKRDRIRNKDRPAM---------QLYQPGARSRNRLCPPDDSTKS 448
S + E ++ +RD +DR + + + +R P DS +
Sbjct: 442 SSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRST 501
Query: 449 GDSAAERKQESGISHRKE 466
D+ R +E +HRKE
Sbjct: 502 RDAHDYRDREGRDTHRKE 519
Score = 40.8 bits (94), Expect = 0.003
Identities = 74/351 (21%), Positives = 127/351 (36%), Gaps = 38/351 (10%)
Query: 134 APFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELI 193
+P +A KK +K + D K +S + S P + E+I +
Sbjct: 224 SPKSSSASKKDRKTSAVSSPLLDQQRNSKTNQS-KKKGPRTPSPPPPIPEDIA------L 276
Query: 194 AKKTTPLLSFLKNKQRMREEKREERRR-REIERKRQREEERRKWKEEEKRKRKDIEKLKK 252
KK K K R+ E+ R+ + R R+ ER+R++ ++ R + +
Sbjct: 277 GKKYKEKY---KVKDRIEEKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHS 333
Query: 253 IDRIPERDKLKDEPKIKLLKKPEKGDEKELDK--REKAKKLDKENLSD--ERASGQSCTL 308
+ P + + P ++ L R A +LS + S
Sbjct: 334 SSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRS 393
Query: 309 PKRSD--------SELKDEKPKRPEDESGRDYRER----EREYERDQERILRERERLKRQ 356
P R S+ D + +R ED G+ RE+ EREYE+DQ R R
Sbjct: 394 PMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQ-----SSSRDHRD 448
Query: 357 EEERRRQKERYEKEKTFKRKE-EEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKR 415
+ E R ++R + T R+E + + +D+ + ++ ES + ++ R
Sbjct: 449 DREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTKESRDPRDSRSTRDAHDYR 508
Query: 416 DRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
DR Y +RS R + + S E + ES R E
Sbjct: 509 DREGRDTHRKEDTYPEESRSYGR-----NHLREESSRTEIRNESRNESRSE 554
Score = 40.4 bits (93), Expect = 0.003
Identities = 43/217 (19%), Positives = 83/217 (38%), Gaps = 30/217 (13%)
Query: 218 RRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKG 277
R R + K + + ER + + +R++ D +RD+ KD + + ++ +
Sbjct: 390 RHRSPMREKGRHDHERTSQSHDRRHERRE-------DTRGKRDREKDSREEREYEQDQSS 442
Query: 278 DEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER 337
D RE D+ + D R EL+D + R D RE R
Sbjct: 443 SRDHRDDREPRDGRDRRDARDTR-----------DRRELRDSRDMR-------DSREM-R 483
Query: 338 EYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAEST 397
+Y RD + R+ ++ R +E + RKE+ +E + + ES+
Sbjct: 484 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTH----RKEDTYPEESRSYGRNHLREESS 539
Query: 398 ESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGAR 434
+ +E + ++ DR+ +L + G+R
Sbjct: 540 RTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSR 576
Score = 36.6 bits (83), Expect = 0.050
Identities = 49/275 (17%), Positives = 97/275 (35%), Gaps = 19/275 (6%)
Query: 211 REEKREERRRREIERKRQREEERRKWKE-EEKRKRKDIEKLKKIDRIPERDKLKDEPKIK 269
R+ +++ R RE E+ + + R +E + R R+D + + + ++D +++
Sbjct: 424 RDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMR 483
Query: 270 LLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESG 329
+ K D R D + + T P+ S S ++ +
Sbjct: 484 DYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEI 543
Query: 330 RDYREREREYERDQERILRERERLKRQEEE-----RRRQKERYEKEKTFKRKEEEMKKEK 384
R+ E E +R+ R R R+ E+ R Q + + + E
Sbjct: 544 RNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYP 603
Query: 385 DTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPG---------ARS 435
+ RD+ + ++ + S + E +RD RP+ + G R
Sbjct: 604 E--RDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERRE 661
Query: 436 RNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
R+ DD + + A ER +E +E E
Sbjct: 662 ERRVDRVDD--RRDERARERDRERERDRERERERE 694
Score = 35.4 bits (80), Expect = 0.11
Identities = 51/256 (19%), Positives = 101/256 (39%), Gaps = 35/256 (13%)
Query: 220 RREIERK----RQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPE 275
RR ER R+R + +R+ + E +KR E + + R + +++ IK+ K+
Sbjct: 75 RRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERT 134
Query: 276 KGDEKELDKREKAKKLDKENLSDERASGQ-SCTLPKRSDSELKDEKPKRPEDESGRDYRE 334
E+E ++ E D+ +G + E+K +K +R + ++ E
Sbjct: 135 PESEEE--------NVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENME 186
Query: 335 REREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDT------LR 388
+ E +E + E R K R+ + K K+ + KK++ T L
Sbjct: 187 KREEIIIKKE-VSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAVSSPLL 245
Query: 389 DKGKKAESTESIGSSEKT---------------EKKEEVVKRDRIRNKDRPAMQLYQPGA 433
D+ + +++ +S +T + KE+ +DRI K R +
Sbjct: 246 DQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRDGKDRGRDFE 305
Query: 434 RSRNRLCPPDDSTKSG 449
R R + P ++ +G
Sbjct: 306 RQREKRDKPRSTSPAG 321
Score = 31.6 bits (70), Expect = 1.6
Identities = 53/295 (17%), Positives = 120/295 (40%), Gaps = 37/295 (12%)
Query: 195 KKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEE----KRKRKDIEKL 250
+ T L +KNK++ + + ++R E ++E R + +E+E ++R +
Sbjct: 80 RPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKERTPESEE 139
Query: 251 KKIDRIPERD-------------KLKDEPK-IKLLKKPEKGDEKELDKREKAKKLDKENL 296
+ ++ RD +L E K K+ ++ K +++ ++KRE+ + K+ +
Sbjct: 140 ENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENMEKREEI--IIKKEV 197
Query: 297 SDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQ 356
S E + P S + PKR +++R+ +L ++ K
Sbjct: 198 SPEVVRSKLSPSPSLRKS---SKSPKRKSSPKSSSASKKDRKTSAVSSPLLDQQRNSKTN 254
Query: 357 EEERRRQK-----ERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEE 411
+ +++ + ++ +K +E K KD + +K + G + + +
Sbjct: 255 QSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIEEKTRD-------GKDRGRDFERQ 307
Query: 412 VVKRDRIRNKDRPAMQLYQP-GARSRNRLCPPDDSTKSGDSAAERKQESGISHRK 465
KRD+ R+ PA Q + P +R + S + + RK+ S+++
Sbjct: 308 REKRDKPRSTS-PAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQR 361
Score = 30.4 bits (67), Expect = 3.6
Identities = 27/87 (31%), Positives = 37/87 (42%), Gaps = 8/87 (9%)
Query: 339 YERDQERI---LRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAE 395
Y R ER LRER + KRQ+ + QK E+ + RKE + ++ K K
Sbjct: 74 YRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKEDIKITKER 133
Query: 396 STESIGSSEKTEKKEEVVKRDRIRNKD 422
+ ES + E E RD N D
Sbjct: 134 TPES-----EEENVEWETNRDDSDNGD 155
>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
Length = 202
Score = 90.5 bits (223), Expect = 3e-18
Identities = 64/203 (31%), Positives = 115/203 (56%), Gaps = 14/203 (6%)
Query: 208 QRMREEKREERRRREIERKRQREEERRKWKEEEKRKR---KDIEKLKKIDRIPERDKLKD 264
+R RE KRE R +E ER+R R+ ER E E R R + E+ ++ DR ER++ K+
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 265 EPKIKLLKKPEKGDEKELDK-REKAKKLDKENLSD-ERASGQSCTLPKRSD-SELKDEKP 321
+ ++ E+ E+E ++ RE+ ++ +++ +D ER + + +D + ++ K
Sbjct: 62 RDR---QRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKG 118
Query: 322 KRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQ----KERYEKEKTFKRKE 377
R D+ R+RERE +R +ER R+R+R +++E +R RQ +E +KE+ +RK+
Sbjct: 119 GRERDKQTERERDRERERQRQRERE-RQRQRERKRETDRERQRWAEREERKKERKKERKK 177
Query: 378 EEMKKEKDTLRDKGKKAESTESI 400
E +K+K+ R + KK + E I
Sbjct: 178 ERKEKKKEEKRREDKKRKWGEGI 200
Score = 72.4 bits (176), Expect = 8e-13
Identities = 51/199 (25%), Positives = 109/199 (54%), Gaps = 17/199 (8%)
Query: 223 IERKRQREEERRKWKEEEK---RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDE 279
+ER+R+R+ E + KE E+ R+R+ + ++ +R +RD+ ++ + + ++ E+ +
Sbjct: 1 MERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDR-QTDREKERERQ 59
Query: 280 KELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDY------- 332
KE D++ + ++ + +R + +++D E ++ + + E+ R+
Sbjct: 60 KERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGG 119
Query: 333 REREREYERDQERILRERERLKRQEEERRRQKER---YEKEKTFKRKEEEMKKEKDTLRD 389
RER+++ ER+++ RERER +++E ER+RQ+ER ++E+ + EE KKE+ R
Sbjct: 120 RERDKQTERERD---RERERQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERK 176
Query: 390 KGKKAESTESIGSSEKTEK 408
K +K + E +K K
Sbjct: 177 KERKEKKKEEKRREDKKRK 195
Score = 64.3 bits (155), Expect = 2e-10
Identities = 48/182 (26%), Positives = 95/182 (52%), Gaps = 11/182 (6%)
Query: 299 ERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERIL-RERERLKRQE 357
ER + + ++E + ++ + E+++ R+ R R+R+ R+++R RE+ER +++E
Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61
Query: 358 EERRRQKERYEKEKTFKRKE----EEMKKEKDTLRDKGKKAE-STESIGSSEKTEK---- 408
+R+RQ+ER + +T +++E E K++ D RDK + E E+ + E+ K
Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRE 121
Query: 409 KEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGG 468
+++ +R+R R ++R Q + R R R D + ERK+E +KE
Sbjct: 122 RDKQTERERDRERER-QRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERK 180
Query: 469 EE 470
E+
Sbjct: 181 EK 182
Score = 62.0 bits (149), Expect = 1e-09
Identities = 48/188 (25%), Positives = 94/188 (50%), Gaps = 16/188 (8%)
Query: 276 KGDEKELDK-REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE 334
K E+E D+ RE+ + ++EN +R + +++D E + E+ K + + R+ RE
Sbjct: 15 KETERERDRQRERENQTERENRHRQRDRHRE--RDRQTDREKERERQKERDRQRQRE-RE 71
Query: 335 REREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMK----KEKDTLRDK 390
ERE ER +ER R+RER ++ + ER + ++R K +T + +E K ++K T R++
Sbjct: 72 TERETERQRER-QRQRERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERER 130
Query: 391 GKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGD 450
++ E ++ ++E +R+R R DR + + R + R K
Sbjct: 131 DRERE-------RQRQRERERQRQRERKRETDRERQRWAEREERKKERKKERKKERKEKK 183
Query: 451 SAAERKQE 458
+R+++
Sbjct: 184 KEEKRRED 191
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 90.5 bits (223), Expect = 3e-18
Identities = 68/287 (23%), Positives = 154/287 (53%), Gaps = 29/287 (10%)
Query: 141 KKKTKKRDTKVGT----IDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
++K ++R+ K+ I + E + E + E+ E ++ E E K REL K
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 197 TTPLLSFLKNKQRMREEKR-EERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
+ K R +EEKR EE + RE E++ +E+E + W++EEK + ++ ++
Sbjct: 354 HE------QEKIREQEEKRQEEEKIREQEKR--QEQEAKMWRQEEKIREQE-------EK 398
Query: 256 IPERDKLKDEPKIKLLKKPEK--GDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSD 313
I E++++ E + K+ ++ EK E+E+ ++E+ + +E + ++ + R
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 314 SELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERY-EKEKT 372
E+ E+ ++ ++ G+ E+E + + +E++ R+ E+++ QE++ R Q+E+ E+E+
Sbjct: 459 EEMMQEQEEKMGEQEGK-MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEM 517
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIR 419
+ +EE+M ++++ + ++ +K + E EK ++EE ++ +R
Sbjct: 518 MQEQEEKMWEQEEKMCEQEEKMQEQE-----EKMRRQEEKMREQEVR 559
Score = 86.7 bits (213), Expect = 4e-17
Identities = 60/306 (19%), Positives = 160/306 (52%), Gaps = 22/306 (7%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE 231
+++ + + L +E+++ + +L A+ L N+Q+ + R+E + +E E K Q +E
Sbjct: 249 QQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQE 308
Query: 232 ERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKL 291
E+ + ++EEK +R++ +K +++ ++++ E + K+ + EK E+E + ++ K+
Sbjct: 309 EKIR-EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQ 367
Query: 292 DKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERE 351
++E + ++ + R + ++++++ K E E +E+E + +E++ + E
Sbjct: 368 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMM--QEQEEKMGEQEEKMWEQEE 425
Query: 352 RLKRQEEERRRQKERY-EKEKTFKRKEEEMKKEKDTLRD--------KGKKAESTESI-G 401
++ QEE+ RRQ+E+ E+EK + +EE+++++++ +++ +GK E +
Sbjct: 426 EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQE 485
Query: 402 SSEKTEKKEEVVK---------RDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSA 452
EK ++EE ++ ++IR ++ + + ++C ++ + +
Sbjct: 486 QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEK 545
Query: 453 AERKQE 458
R++E
Sbjct: 546 MRRQEE 551
Score = 75.5 bits (184), Expect = 1e-13
Identities = 56/241 (23%), Positives = 133/241 (55%), Gaps = 31/241 (12%)
Query: 164 LESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREI 223
LE + EK+ E EE + + +E K+ + ++++RE+ EE+ R +
Sbjct: 349 LEEKMHEQEKIREQEEKRQEEEKIREQE---KRQEQEAKMWRQEEKIREQ--EEKIREQE 403
Query: 224 ERKRQREE-----ERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGD 278
E +++EE E + W++EE+ + ++ EK+++ + +K++++ K K+ ++ EK
Sbjct: 404 EMMQEQEEKMGEQEEKMWEQEEEMQEQE-EKMRR-----QEEKIREQEK-KIREQEEKIR 456
Query: 279 EKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERERE 338
E+E +E+ +K+ ++ G+ C + + + ++EK +R E++ RE+E++
Sbjct: 457 EQEEMMQEQEEKMGEQ-------EGKMC--EQEAKMQEQEEKMRRQEEK----IREQEKK 503
Query: 339 YERDQERILRERERLKRQEEERRRQKERY-EKEKTFKRKEEEMKKEKDTLRDKGKKAEST 397
+E+I + E ++ QEE+ Q+E+ E+E+ + +EE+M+++++ +R++ +
Sbjct: 504 IREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQ 563
Query: 398 E 398
E
Sbjct: 564 E 564
Score = 75.1 bits (183), Expect = 1e-13
Identities = 65/276 (23%), Positives = 149/276 (53%), Gaps = 37/276 (13%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE 231
E+ E ++E E K RE K ++ ++ M EK E+ RR+E E ++EE
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEK--------MRRQEEMMWEKEEKMRRQE-EMMWEKEE 344
Query: 232 ERRKWKE---EEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKA 288
+ R+ +E E+++ R+ EK ++ ++I E++K + E + K+ ++ EK E+E RE+
Sbjct: 345 KIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQE 403
Query: 289 KKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYE---RDQER 345
+ + ++ +E+ Q + ++ + + E+ R ++E R+ ++ RE E R+QE
Sbjct: 404 EMMQEQ---EEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 460
Query: 346 ILRERE-RLKRQE----EERRRQKERYEK-----------EKTFKRKEEEMKKEKDTLRD 389
+++E+E ++ QE E+ + +E+ EK EK + +EE+++++++ +++
Sbjct: 461 MMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 520
Query: 390 KGKK--AESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
+ +K + + EK +++EE ++R + +++
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQ 556
Score = 69.7 bits (169), Expect = 5e-12
Identities = 72/336 (21%), Positives = 160/336 (47%), Gaps = 40/336 (11%)
Query: 159 EYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKRE-- 216
E + L + AT +K E L +E +A + EL T LK K +EK +
Sbjct: 164 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITD--EELKEKNAKLQEKLQLV 221
Query: 217 ERRRREIE---RKRQREEERRKWKEEEKRKRKDIEKL-KKIDRIPER-----------DK 261
E + EI+ ++ +R+ ER K +++ + + + L K++ + + ++
Sbjct: 222 ESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR 281
Query: 262 LKDEPKIKLLKKPEKGDEKE---LDKREKAKKLDKENLSDERASGQSCTLPKRSDSEL-- 316
L + + K+ ++ EK E+E ++ EK ++ +++ E + +R + +
Sbjct: 282 LNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE 341
Query: 317 KDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERR--RQKERY-EKEKTF 373
K+EK + E++ + RE+E +R +E +RE+E KRQE+E + RQ+E+ E+E+
Sbjct: 342 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE--KRQEQEAKMWRQEEKIREQEEKI 399
Query: 374 KRKEEEMKKEKDTLRDKGKK--AESTESIGSSEKTEKKEEVVK---------RDRIRNKD 422
+ +EE M+++++ + ++ +K + E EK ++EE ++ ++IR ++
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459
Query: 423 RPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
+ + ++C + + + R++E
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEE 495
Score = 68.6 bits (166), Expect = 1e-11
Identities = 58/262 (22%), Positives = 130/262 (49%), Gaps = 10/262 (3%)
Query: 212 EEKREERRRREIERKRQRE--EERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIK 269
++K+ +R E+ ++R E R +E+ K K+ + +K+ + E +K + + +K
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLV-ESEKSEIQLNVK 233
Query: 270 LLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESG 329
LK+ K + +L ++ + + ++L E S + + ++EL + ++ E++
Sbjct: 234 ELKR--KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKM- 290
Query: 330 RDYREREREYERDQERILRERERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLR 388
+R+ E+ ER+ E+I + E+++ QEE+ RRQ+E +EKE+ +R+EE M ++++ +R
Sbjct: 291 --WRQEEKIQERE-EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 389 DKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKS 448
+ +K E I E+ ++EE ++ R + M + R + +
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ 407
Query: 449 GDSAAERKQESGISHRKEGGEE 470
+QE + ++E +E
Sbjct: 408 EQEEKMGEQEEKMWEQEEEMQE 429
Score = 42.7 bits (99), Expect = 7e-04
Identities = 29/143 (20%), Positives = 73/143 (51%), Gaps = 5/143 (3%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K R+ + + + + R+ E EKM + E+ EAK +E K
Sbjct: 432 EKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ-EAKMQEQEEKM 490
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
+ ++++RE++ + R + E+ +E+E + W++EEK ++ + ++ +++
Sbjct: 491 RRQEEKIREQEKKIREQEEKIREQEEM----MQEQEEKMWEQEEKMCEQEEKMQEQEEKM 546
Query: 257 PERDKLKDEPKIKLLKKPEKGDE 279
+++ E +++L ++ EK E
Sbjct: 547 RRQEEKMREQEVRLRQQEEKMQE 569
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 90.5 bits (223), Expect = 3e-18
Identities = 75/243 (30%), Positives = 124/243 (51%), Gaps = 32/243 (13%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKR 242
E ++++R K +K K+R++E+ RE+ R R E++R++E+ER K K+ +K
Sbjct: 363 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER--EKEREKEKERGKNKDRDKE 420
Query: 243 KRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE--R 300
+ KD EK K+ DR ER+K ++ + K K+ E+ EKE +K +++K++D++ D+ R
Sbjct: 421 REKDREKDKEKDREREREKEHEKDRDK-EKEKEQDKEKEREK-DRSKEIDEKRKKDKKSR 478
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDES--------------------GRDYREREREYE 340
+S +RS S ++ + +R S R+ ++++RE E
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Query: 341 RD--QERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK---GKKAE 395
RD ER RER R+ R KE+ EK T KE+E KE D+ K K A
Sbjct: 539 RDHISERRERERSTSMRKSSNDRDGKEKLEKNST-SLKEKEHNKEPDSSVSKEVDDKDAP 597
Query: 396 STE 398
TE
Sbjct: 598 RTE 600
Score = 88.6 bits (218), Expect = 1e-17
Identities = 73/256 (28%), Positives = 122/256 (47%), Gaps = 33/256 (12%)
Query: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL 270
RE+ +E+ R +E +R+++RE E+ + KE+E+ K KD +K ++ DR E+DK KD + +
Sbjct: 381 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR--EKDKEKDRERER- 437
Query: 271 LKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
EK EK+ DK EK K+ DKE ER +S + ++ + K P R + S R
Sbjct: 438 ----EKEHEKDRDK-EKEKEQDKEK---EREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 489
Query: 331 ---DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTL 387
RER R R R R + +KR+ + R +K+K + +KE+D +
Sbjct: 490 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK-------KREKERDHI 542
Query: 388 RDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTK 447
++ ++ ST SS + KE++ K + + N+ S +
Sbjct: 543 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE------------KEHNKEPDSSVSKE 590
Query: 448 SGDSAAERKQESGISH 463
D A R +E+ I H
Sbjct: 591 VDDKDAPRTEENKIQH 606
Score = 87.8 bits (216), Expect = 2e-17
Identities = 72/269 (26%), Positives = 121/269 (44%), Gaps = 44/269 (16%)
Query: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL 270
R+ + + R R R R R+++RR+ K K++ K E+ K R RDK KD
Sbjct: 326 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT----- 380
Query: 271 LKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
+++ ++E+ K+ D+E K + E + EK K R
Sbjct: 381 --------REKIKEKERVKEKDRE---------------KEREREKEREKEKERGKNKDR 417
Query: 331 DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK 390
D +ERE++ E+D+E+ +RER + +E E+ R KE+ +++ K +E++ KE D R K
Sbjct: 418 D-KEREKDREKDKEK---DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 473
Query: 391 GKKAES-TESIGSSEKTEKKEEVVKRDRIRNKDR--------PAMQLYQPGARSRNRLCP 441
KK+ + S +S ++ +R R R+ R P RSRN+
Sbjct: 474 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK--K 531
Query: 442 PDDSTKSGDSAAERKQ-ESGISHRKEGGE 469
K D +ER++ E S RK +
Sbjct: 532 DKKREKERDHISERRERERSTSMRKSSND 560
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 90.5 bits (223), Expect = 3e-18
Identities = 75/243 (30%), Positives = 124/243 (51%), Gaps = 32/243 (13%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKR 242
E ++++R K +K K+R++E+ RE+ R R E++R++E+ER K K+ +K
Sbjct: 247 ERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERER--EKEREKEKERGKNKDRDKE 304
Query: 243 KRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE--R 300
+ KD EK K+ DR ER+K ++ + K K+ E+ EKE +K +++K++D++ D+ R
Sbjct: 305 REKDREKDKEKDREREREKEHEKDRDK-EKEKEQDKEKEREK-DRSKEIDEKRKKDKKSR 362
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDES--------------------GRDYREREREYE 340
+S +RS S ++ + +R S R+ ++++RE E
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Query: 341 RD--QERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK---GKKAE 395
RD ER RER R+ R KE+ EK T KE+E KE D+ K K A
Sbjct: 423 RDHISERRERERSTSMRKSSNDRDGKEKLEKNST-SLKEKEHNKEPDSSVSKEVDDKDAP 481
Query: 396 STE 398
TE
Sbjct: 482 RTE 484
Score = 88.6 bits (218), Expect = 1e-17
Identities = 73/256 (28%), Positives = 122/256 (47%), Gaps = 33/256 (12%)
Query: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL 270
RE+ +E+ R +E +R+++RE E+ + KE+E+ K KD +K ++ DR E+DK KD + +
Sbjct: 265 REKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR--EKDKEKDRERER- 321
Query: 271 LKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
EK EK+ DK EK K+ DKE ER +S + ++ + K P R + S R
Sbjct: 322 ----EKEHEKDRDK-EKEKEQDKEK---EREKDRSKEIDEKRKKDKKSRTPPRSYNASRR 373
Query: 331 ---DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTL 387
RER R R R R + +KR+ + R +K+K + +KE+D +
Sbjct: 374 SRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK-------KREKERDHI 426
Query: 388 RDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTK 447
++ ++ ST SS + KE++ K + + N+ S +
Sbjct: 427 SERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE------------KEHNKEPDSSVSKE 474
Query: 448 SGDSAAERKQESGISH 463
D A R +E+ I H
Sbjct: 475 VDDKDAPRTEENKIQH 490
Score = 87.8 bits (216), Expect = 2e-17
Identities = 72/269 (26%), Positives = 121/269 (44%), Gaps = 44/269 (16%)
Query: 211 REEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL 270
R+ + + R R R R R+++RR+ K K++ K E+ K R RDK KD
Sbjct: 210 RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT----- 264
Query: 271 LKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
+++ ++E+ K+ D+E K + E + EK K R
Sbjct: 265 --------REKIKEKERVKEKDRE---------------KEREREKEREKEKERGKNKDR 301
Query: 331 DYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDK 390
D +ERE++ E+D+E+ +RER + +E E+ R KE+ +++ K +E++ KE D R K
Sbjct: 302 D-KEREKDREKDKEK---DREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK 357
Query: 391 GKKAES-TESIGSSEKTEKKEEVVKRDRIRNKDR--------PAMQLYQPGARSRNRLCP 441
KK+ + S +S ++ +R R R+ R P RSRN+
Sbjct: 358 DKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK--K 415
Query: 442 PDDSTKSGDSAAERKQ-ESGISHRKEGGE 469
K D +ER++ E S RK +
Sbjct: 416 DKKREKERDHISERRERERSTSMRKSSND 444
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 89.0 bits (219), Expect = 9e-18
Identities = 79/293 (26%), Positives = 149/293 (50%), Gaps = 43/293 (14%)
Query: 161 RKFLESYATDNEKMTST--PETLLEEIEAKNRELIAKKTTPLLSFL-KNKQRM----REE 213
R FL + + MT T P ++++ +N L + P SF+ K +QR+ R+E
Sbjct: 493 RTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPL---RMDPKCSFVEKERQRLENLRRKE 549
Query: 214 KREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLL-K 272
+ E+ RR+++E ++R E K K EE R RK ++ ++++++ E K + E K + +
Sbjct: 550 EAEQLRRQKVEEDKRRRLEEVKLKREE-RLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 608
Query: 273 KPEKGDEKEL-----DKREKAKKLDK-----------------ENLSDERASGQSCTLPK 310
K EK E+ L K+ AKK+++ + +ER + K
Sbjct: 609 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 668
Query: 311 RSDSEL--KDEKPKRPEDESGRDYREREREYE--RDQERILRERERLKRQ--EEERRRQK 364
+ E K + KR ++ ++ RE+ER + R+QER +ER +RQ E+ERRR++
Sbjct: 669 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 728
Query: 365 ERYEKEKTFKRKEEEMKKEKDTLR---DKGKKAESTESIGSSEKTEKKEEVVK 414
ER + E+ + +E+ ++ +K+ L+ ++ KK E + + + E++E+ K
Sbjct: 729 ERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Score = 86.3 bits (212), Expect = 6e-17
Identities = 77/313 (24%), Positives = 159/313 (50%), Gaps = 35/313 (11%)
Query: 161 RKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKRE--ER 218
R+ E+ +K+ LEE++ K E + K +L + ++M+EEK++ E+
Sbjct: 546 RRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRK----VLQARERVEQMKEEKKKQIEQ 601
Query: 219 RRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGD 278
+ +I+ K ++ +E R +E+ K+K KK++ + R K ++E + + E+ +
Sbjct: 602 KFAQIDEKTEKAKEERLAEEKAKKKAA----AKKMEEVEARRKQEEEARRLRWLQQEEEE 657
Query: 279 EKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERERE 338
+ + +K K+ ++E L R + ++ L ++ + E ++++ +R ++ ++ RE+ER
Sbjct: 658 RRHQELLQKKKEEEQERL---RKAAEAKRLAEQREQERREQE-RREQERREQERREQER- 712
Query: 339 YERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTE 398
R+QER L E+ER +R++E + ++E E+EK + ++E++++E + + K ++ E
Sbjct: 713 --REQERQLAEQER-RREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAE 769
Query: 399 SIGSSEKTEKKEEVVKRDRIRN----KDRPAMQLYQ---PGARSRNRLCP--------PD 443
E+ +K +E + N PA YQ G R+ ++ P D
Sbjct: 770 RQLQEEQEKKAKEAAGASKALNVTVDVQSPACTSYQMTPQGHRAPPKINPDNYGMDLNSD 829
Query: 444 DSTKSGDSAAERK 456
DST D A RK
Sbjct: 830 DST--DDEAHPRK 840
Score = 63.2 bits (152), Expect = 5e-10
Identities = 51/207 (24%), Positives = 110/207 (53%), Gaps = 24/207 (11%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
++ ++K K+ + K ID+ E K E + + +EE+EA+ ++ +
Sbjct: 589 EQMKEEKKKQIEQKFAQIDEKTEKAK--EERLAEEKAKKKAAAKKMEEVEARRKQEEEAR 646
Query: 197 TTPLLSFLKNKQRMRE------EKREERRRREIERKR---QREEERRKW--KEEEKR--K 243
L + ++R +E E+ +ER R+ E KR QRE+ERR+ +E+E+R +
Sbjct: 647 RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQE 706
Query: 244 RKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASG 303
R++ E+ ++ ++ E+++ +++ +++ E+EL +REKA +L KE L E
Sbjct: 707 RREQERREQERQLAEQERRREQERLQA--------ERELQEREKALRLQKEQLQRELEEK 758
Query: 304 QSCTLPKR-SDSELKDEKPKRPEDESG 329
+ +R ++ +L++E+ K+ ++ +G
Sbjct: 759 KKKEEQQRLAERQLQEEQEKKAKEAAG 785
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/203 (21%), Positives = 86/203 (42%), Gaps = 12/203 (5%)
Query: 224 ERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDE----PKIKLLKKPEKGDE 279
E K + + R+ + +RKR + + ++D E L+DE P+ K P +
Sbjct: 431 EAKTDQADGPREPPQSARRKRSYKQAVSELD---EEQHLEDEELQPPRSKTPSSPCPASK 487
Query: 280 KELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREY 339
R + + + S + S +K P R + + +ER+R
Sbjct: 488 VVRPLRTFLHTVQRNQMLMTPTSAPRSVMK----SFIKRNTPLRMDPKCSFVEKERQRLE 543
Query: 340 ERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTES 399
++ + R K +E++RRR +E K + RK + ++ + ++++ KK +
Sbjct: 544 NLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKF 603
Query: 400 IGSSEKTEK-KEEVVKRDRIRNK 421
EKTEK KEE + ++ + K
Sbjct: 604 AQIDEKTEKAKEERLAEEKAKKK 626
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 88.6 bits (218), Expect = 1e-17
Identities = 65/283 (22%), Positives = 150/283 (53%), Gaps = 17/283 (6%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREE 231
EKM + + E+ E K R+ K + +R+RE++ R ++++ ++ ++
Sbjct: 479 EKMREQEDQMWEQ-EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Query: 232 ERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKL 291
E +K +E+EK+ EK+++ +R+ ER+K E + + ++ EK E+E RE+ +K+
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKM 597
Query: 292 DKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERE 351
++ +E+ Q + ++ + + E+ + +++ + E+E + + +E++ + E
Sbjct: 598 WEQ---EEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW-EQEEKMQEQEEKMWEQEE 653
Query: 352 RLKRQEEERRRQKERYE-KEKTFKRKEEEMKKEKDTLRDKGKKAESTESI---------G 401
+++ QEE+ R Q+E+ + +E+ + +EE+M+ +++ +R++ +K E G
Sbjct: 654 KMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWG 713
Query: 402 SSEKTEKKEEV-VKRDRIRN-KDRPAMQLYQPGARSRNRLCPP 442
EK +EE+ K +RIR+ K++ +L + R PP
Sbjct: 714 QEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPP 756
Score = 84.0 bits (206), Expect = 3e-16
Identities = 66/293 (22%), Positives = 151/293 (51%), Gaps = 24/293 (8%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRR----EIERKRQREE---ERRK 235
EE++ KN EL K + + ++E KR+ R + +++ +EE + +
Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242
Query: 236 WKEEEKRKRKDIEKL-KKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKE 294
+E+EK+ RK EK+ ++ +R+ E++ E + K+ ++ ++ E+E + RE+ K+L ++
Sbjct: 243 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQ 302
Query: 295 NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLK 354
E+ + ++++++ K E E RE+E + R +ER+ + ++++
Sbjct: 303 KKLREQ------------EEQMQEQEEKMWEQEE--KMREQEEKMWRQEERLWEQEKQMR 348
Query: 355 RQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVV 413
QE++ R Q+ER +E+++ + KEE M +E++ + ++ +K + E I EK ++EE
Sbjct: 349 EQEQKMRDQEERMWEQDERLREKEERM-REQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 414 KRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
R++ + +++ + + P+ K + ++QE I ++E
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Score = 82.0 bits (201), Expect = 1e-15
Identities = 49/214 (22%), Positives = 121/214 (56%), Gaps = 10/214 (4%)
Query: 205 KNKQRMREEK-REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKL- 262
+ K+ R+EK RE+ + + ++ R++E++ W +EE+ +D +K +R+ E+ K+
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 263 KDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPK 322
+ E K++ KK ++ ++K D+ EK ++ ++ +++ + + ++ + + E+
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 323 RPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKER---YEKEKTFKRKEEE 379
R ++E E+E + + +E++ + E++ QEEE + Q++ +E+E+ + +EE+
Sbjct: 591 REQEEK---MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 380 MKKEKDTLRDKGKKAESTES--IGSSEKTEKKEE 411
M ++++ +R++ +K E G EK ++EE
Sbjct: 648 MWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/345 (20%), Positives = 174/345 (50%), Gaps = 24/345 (6%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+++ K RD + + D R+ E + EKM E + EE + RE ++
Sbjct: 349 EQEQKMRDQEERMWEQDERLRE-KEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERD 260
+ + K + +EE E+ +E +++R E++ + W E+EK + ++ + ++ ++I +++
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLW-EQEKMQEQEEKIWEQEEKIRDQE 466
Query: 261 KLKDEPKI-----KLLKKPEKGDEKELDKREKAKKL-DKENL---SDERASGQSCTLPKR 311
++ + K K+ ++ ++ E+E R++ +K+ D+E DER + + ++
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ 526
Query: 312 S-----DSELKDEKPKRPEDESGRDYREREREYER--DQERILRERERLKRQEEERRRQK 364
+ ++++EK + +++ D E+ RE ER ++E+ +RE E + R++EE+ +++
Sbjct: 527 KKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ 586
Query: 365 ER--YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVV-KRDRIRNK 421
E E+E+ +EE+M+++++ + ++ +K E +K +++EE++ +++ +
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE---EEDKMQEQEEMMWEQEEKMQE 643
Query: 422 DRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
M + R + + G R+QE + ++E
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688
Score = 80.9 bits (198), Expect = 2e-15
Identities = 73/299 (24%), Positives = 152/299 (50%), Gaps = 24/299 (8%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLE------EIEAKNR 190
+K +++ K R+ + + + + + E EKM E L E E E K R
Sbjct: 296 EKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 355
Query: 191 ELIAKKTTPLLSFLKNKQRMREEKR---------EERRRREIERKRQREEERRKWKEEEK 241
+ + + ++RMRE+++ EE R RE E+K REEE ++EEK
Sbjct: 356 DQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKK-MREEEETMREQEEK 414
Query: 242 RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENL-SDER 300
++++ ++ ++ ++ +L E K KL ++ + +++E ++ K D+E + E+
Sbjct: 415 MQKQEENMWEQEEKEWQQQRL-PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK 473
Query: 301 ASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYE---RDQERILRERERLKRQE 357
+ + ++ D + E+ R +++ D ER E + R++E +RE++++ +QE
Sbjct: 474 KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE 533
Query: 358 EERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI--GSSEKTEKKEEVVK 414
E+ R +K+ E+EK +EE+M +E++ +R++ KK E + EK +++EE ++
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKM-REEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Score = 80.9 bits (198), Expect = 2e-15
Identities = 54/256 (21%), Positives = 138/256 (53%), Gaps = 12/256 (4%)
Query: 170 DNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEK--REERRRREIERKR 227
+ EKM E + E+ E K R+ + + K R +E++ +E + R+ E+K
Sbjct: 444 EQEKMQEQEEKIWEQ-EEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKM 502
Query: 228 QREEER-----RKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKEL 282
+EER + +E+E+R R+ + ++ +++ E K +++ K ++ + +E+ +
Sbjct: 503 WDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERM 562
Query: 283 DKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD 342
+REK + ++E + ++ Q R E E+ ++ +++ + + + E+ +E++
Sbjct: 563 REREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE 622
Query: 343 QERILRERERLKRQEEERRRQKER--YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTES- 399
+E ++E+E + ++EE+ +++E +E+E+ + +EE+M+++++ ++ + +K E
Sbjct: 623 EEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEK 682
Query: 400 -IGSSEKTEKKEEVVK 414
G EK ++EE ++
Sbjct: 683 MQGQEEKMREQEEKMR 698
Score = 80.5 bits (197), Expect = 3e-15
Identities = 74/365 (20%), Positives = 178/365 (48%), Gaps = 40/365 (10%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLE---EIEAKNRELIAKKT 197
+KK +K++ K+ ++ R+ EKM + L E E+ + +EL +K
Sbjct: 247 EKKIRKQEEKMWRQEE--RLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKK 304
Query: 198 TPLLSFLKNKQRMREEK--REERRRREIERKRQREEER-----RKWKEEEKRKRKDIEKL 250
L + + + +EEK +E + RE E K R+EER ++ +E+E++ R E++
Sbjct: 305 ---LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERM 361
Query: 251 --------KKIDRIPER-------DKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKEN 295
+K +R+ E+ +K+++E +I+ +K + +E+ + ++E+ + +EN
Sbjct: 362 WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEEN 421
Query: 296 L-SDERASGQSCTLPKRSDSELKDEKPKRPED---ESGRDYREREREYERD-----QERI 346
+ E Q LP++ + + EK + E+ E R++E + ++ QE++
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 347 LRERERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEK 405
+ +++ QEE+ R Q+++ +++E+ ++E ++++++ +R++ K + E + +K
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKK 541
Query: 406 TEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRK 465
T+++E+ + ++ M+ + R + + R+QE + ++
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 466 EGGEE 470
E +E
Sbjct: 602 EKMQE 606
Score = 78.6 bits (192), Expect = 1e-14
Identities = 73/276 (26%), Positives = 143/276 (51%), Gaps = 39/276 (14%)
Query: 159 EYRKFLESYATDN---EKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKR 215
E KFL N E+M E L E+ E K R+ K + + +MRE++
Sbjct: 218 ERAKFLLPQVQTNTLQEEMWRQEEELREQ-EKKIRKQEEKMWRQEERLREQEGKMREQE- 275
Query: 216 EERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPE 275
E+ RR+ +R R++E+E R E+EK R E+ KL+++ + ++ ++ E
Sbjct: 276 -EKMRRQEKRLREQEKELR---EQEKELR-------------EQKKLREQEE-QMQEQEE 317
Query: 276 KGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRER 335
K E+E RE+ +K+ ++ +ER Q + ++ E+ +DE R+ ER
Sbjct: 318 KMWEQEEKMREQEEKMWRQ---EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 336 EREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKK-- 393
RE QE++ + E+++ +E R R+K+ E+E+T + +EE+M+K+++ + ++ +K
Sbjct: 375 MRE----QEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
Query: 394 -----AESTESIGSSEKTEKKEEVV--KRDRIRNKD 422
E E + EK +++EE + + ++IR+++
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466
Score = 73.6 bits (179), Expect = 4e-13
Identities = 63/271 (23%), Positives = 147/271 (54%), Gaps = 19/271 (7%)
Query: 159 EYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREER 218
E ++ L + +T ++K E L +E +A + EL T KN + + + E
Sbjct: 142 ELQRALSAVSTWHKKADRYIEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAES 201
Query: 219 RRREIE---RKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPE 275
+ EI+ ++ +R+ ER K+ + + E++ + + ++L+++ K K+ K+ E
Sbjct: 202 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWR-----QEEELREQEK-KIRKQEE 255
Query: 276 KGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRER 335
K +E RE+ K+ ++ +E+ Q L + + EL++++ + E + RE+
Sbjct: 256 KMWRQEERLREQEGKMREQ---EEKMRRQEKRL-REQEKELREQEKELREQ---KKLREQ 308
Query: 336 EREYERDQERILRERERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKK- 393
E + + +E++ + E+++ QEE+ RQ+ER +E+EK + +E++M+ +++ + ++ ++
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERL 368
Query: 394 AESTESIGSSEKT-EKKEEVVKRDRIRNKDR 423
E E + EK E++E++ + +RIR +++
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREK 399
Score = 73.6 bits (179), Expect = 4e-13
Identities = 59/277 (21%), Positives = 141/277 (50%), Gaps = 27/277 (9%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K ++ K R+ + + + + R + E+M E L E+ E + KK
Sbjct: 472 EKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ---KK 528
Query: 197 TTPLLSFLKNKQRMREEKR-EERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR 255
+ +++MREEK+ +E+ ++ +++ + EE R + E+K + ++ ++ ++
Sbjct: 529 ------MWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 256 IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKL------DKENLSDERASGQSCTLP 309
+ E+++ E + K+ ++ EK E+E E+ +K+ DK +E Q +
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQ 642
Query: 310 KRSDSELKDEKPKRPEDESGRDYRER----EREYERDQERILRERERLKRQEEERRRQKE 365
++ + + E+ R ++E R+ E+ E + +E++ + E+++ QEE+ R Q+E
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEE 702
Query: 366 RY--EKEKTFKRKE-----EEMKKEKDTLRDKGKKAE 395
+ ++EK + ++E EEM+++++ +RD+ +K +
Sbjct: 703 KMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ 739
Score = 41.2 bits (95), Expect = 0.002
Identities = 35/146 (23%), Positives = 70/146 (47%), Gaps = 21/146 (14%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
++K +++ K+ +++ + ++ E EKM E + E+ E K RE K
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ-EEKMREQEEKMREQE 666
Query: 201 LSFLKNKQRMREEK-----REERRRREIERKRQREE------------ERRKWKEEEKRK 243
+++MRE++ +EE+ R + E+ R +EE E + W +EE R+
Sbjct: 667 EKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMRE 726
Query: 244 RKDI---EKLKKIDRIPERDKLKDEP 266
+++ +K K +R+PE ++ EP
Sbjct: 727 KEERIRDQKEKMQERLPEHEERCSEP 752
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 88.6 bits (218), Expect = 1e-17
Identities = 84/342 (24%), Positives = 164/342 (47%), Gaps = 69/342 (20%)
Query: 135 PFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTP----------ETLLEE 184
P Q A +K++ K+ V +D++ E K S+P T L
Sbjct: 443 PPQSARRKRSYKQ--AVSELDEEQHLED--EELQPPRSKTPSSPCPASKVVRPLRTFLHT 498
Query: 185 IEAKNRELIAKKTTP---LLSFLKNKQRMREEKREERRRR--EIERKRQREEERRKWKEE 239
++ +N+ L+ + P + SF+K +R + +E+ R+R + RK + E+ RR+ EE
Sbjct: 499 VQ-RNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEE 557
Query: 240 EKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKG--DEKELDKREKAKKLDKENLS 297
+KR+R + KLK+ +R+ R L+ +++ +K+ +K ++K EK +K +E L+
Sbjct: 558 DKRRRLEEVKLKREERL--RKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLA 615
Query: 298 DERASGQSCT----------------------------------LPKRSDSEL----KDE 319
+E+A ++ L K+ + E K
Sbjct: 616 EEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 675
Query: 320 KPKRPEDESGRDYREREREYE--RDQERILRERERLKRQ--EEERRRQKERYEKEKTFKR 375
+ KR ++ ++ RE+ER + R+QER +ER +RQ E+ERRR++ER + E+ +
Sbjct: 676 EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQE 735
Query: 376 KEEEMKKEKDTLR---DKGKKAESTESIGSSEKTEKKEEVVK 414
+E+ ++ +K+ L+ ++ KK E + + + E++E+ K
Sbjct: 736 REKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Score = 86.7 bits (213), Expect = 4e-17
Identities = 84/343 (24%), Positives = 171/343 (49%), Gaps = 43/343 (12%)
Query: 138 KAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNE-------KMTSTPETLLEEIEAKNR 190
++ K KR+T + +D + R+ LE+ E K+ LEE++ K
Sbjct: 513 RSVMKSFIKRNTPL-RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
Query: 191 ELIAKKTTPLLSFLKNKQRMREEKRE--ERRRREIERKRQREEERRKWKEEEKRKRKDIE 248
E + K +L + ++M+EEK++ E++ +I+ K ++ +E R +E+ K+K
Sbjct: 572 ERLRK----VLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA--- 624
Query: 249 KLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTL 308
KK++ + R K ++E + + E+ + + + +K K+ ++E L R + ++ L
Sbjct: 625 -AKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERL---RKAAEAKRL 680
Query: 309 PKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYE 368
++ + E ++++ +R ++ ++ RE+ER R+QER L E+ER +R++E + ++E E
Sbjct: 681 AEQREQERREQE-RREQERREQERREQER---REQERQLAEQER-RREQERLQAERELQE 735
Query: 369 KEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRN----KDRP 424
+EK + ++E++++E + + K ++ E E+ +K +E + N P
Sbjct: 736 REKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795
Query: 425 AMQLYQ---PGARSRNRLCP--------PDDSTKSGDSAAERK 456
A YQ G R+ ++ P DDST D A RK
Sbjct: 796 ACTSYQMTPQGHRAPPKINPDNYGMDLNSDDST--DDEAHPRK 836
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 87.8 bits (216), Expect = 2e-17
Identities = 75/283 (26%), Positives = 131/283 (46%), Gaps = 71/283 (25%)
Query: 147 RDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKN 206
R K+GT + P ++ S + TPE L + E K T L S ++
Sbjct: 475 RKAKLGTPSNMPPNFPYISSPSVS----PPTPEPLHKVYEEK---------TKLPSSVEV 521
Query: 207 KQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR---IPERDKLK 263
K+++++E + + +++E +R R+RE+++ K K +EK K K+ EK K+ R P ++ LK
Sbjct: 522 KKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLK 581
Query: 264 DE----------------PKIKLL--------------KKPEKGDEKELDKREKAKKLDK 293
+E PK+KL KK + +K+ DKREK K DK
Sbjct: 582 EEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDK 641
Query: 294 ENLSDERASGQSCTLPKRS-------------------------DSELKDEKPKRPEDES 328
+A LP + +L +EK K E E
Sbjct: 642 GREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEK 701
Query: 329 GRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEK 371
+D +E++++ E+++E+ +ERE+ KR+ E+R ++KE+++ EK
Sbjct: 702 KKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEK 744
Score = 53.9 bits (128), Expect = 3e-07
Identities = 43/148 (29%), Positives = 83/148 (56%), Gaps = 16/148 (10%)
Query: 248 EKLKKIDRIPERDKLKDEPKIKLLKKPEKGD-EKELDK-REKAKKLDKENLSDERASGQS 305
EK K + + KLK E K K+ KK ++ D E+E DK ++K+K+ DK ++
Sbjct: 511 EKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEK------ 564
Query: 306 CTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKE 365
K + E K + ++E Y+ + +E+E D + ++ ++ L R+E+E+ + K+
Sbjct: 565 ---DKETGRETKYPWKEFLKEEEADPYKFKIKEFE-DVDPKVKLKDGLVRKEKEKHKDKK 620
Query: 366 RYEKEKTFKRKEEEMKKEKDTLRDKGKK 393
+ ++EK K K+ K+EK+ ++DKG++
Sbjct: 621 K-DREKGKKDKD---KREKEKVKDKGRE 644
Score = 45.8 bits (107), Expect = 8e-05
Identities = 30/135 (22%), Positives = 66/135 (48%), Gaps = 9/135 (6%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAK-------NRELI 193
K K KK+D + G D D ++ ++ +++ P +L E +
Sbjct: 615 KHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRV 674
Query: 194 AKKTTPLLSFLKNK--QRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLK 251
LL L K + + K +E+++ + E+K+++E+E+ K ++E ++++++ EK +
Sbjct: 675 PAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKRE 734
Query: 252 KIDRIPERDKLKDEP 266
K + +K+K EP
Sbjct: 735 KEKEKHKHEKIKVEP 749
>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
Length = 285
Score = 85.5 bits (210), Expect = 9e-17
Identities = 55/190 (28%), Positives = 107/190 (56%), Gaps = 15/190 (7%)
Query: 209 RMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKI 268
R RE +RE R+R+ ++R RE++R K+ ++++++D E+ + DR +R++ D +
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117
Query: 269 KLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDES 328
++ E+ + + KREK + ER + + K D E++ EK + E E
Sbjct: 118 TETERQEERERQRDRKREKDR---------ERQRQREIGIDK--DREIETEKDRDREREM 166
Query: 329 GRDYREREREYERDQERIL---RERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKD 385
G R R+RE ER ++R R+RER +R++E+R R ++R ++ + + +E E +++D
Sbjct: 167 GETERYRDRERERQKQRETRRDRDRER-QREKEDRERDRDRQKEREKDRYRERETGRDRD 225
Query: 386 TLRDKGKKAE 395
RD+ ++ E
Sbjct: 226 KERDRERQRE 235
Score = 79.3 bits (194), Expect = 7e-15
Identities = 55/205 (26%), Positives = 109/205 (53%), Gaps = 26/205 (12%)
Query: 221 REIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEK 280
RE ER+R+RE +R++ KE + K ++IEK + DR +RD+ + + + K+ GD
Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDR--DRQRKRDRERQRWRDRDRKRERWGDRD 115
Query: 281 ELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDY-REREREY 339
+ E+ ++ +++ D + + ++ ++ + E G D RE E E
Sbjct: 116 RETETERQEERERQR-----------------DRKREKDRERQRQREIGIDKDREIETEK 158
Query: 340 ERDQERILRERERLKRQEEERRRQKE-RYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTE 398
+RD+ER + E ER + +E ER++Q+E R ++++ +R++E+ ++++D +++ K
Sbjct: 159 DRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKEREKDRYRER 218
Query: 399 SIGSSEKTEKKEEVVKRDRIRNKDR 423
G E+ R+R R KDR
Sbjct: 219 ETGRDRDKER-----DRERQREKDR 238
Score = 61.6 bits (148), Expect = 1e-09
Identities = 38/151 (25%), Positives = 83/151 (54%), Gaps = 20/151 (13%)
Query: 205 KNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKD 264
+ ++R + RE R+ ER+RQR+ +R K +E ++++ I+K ++I+ +RD+ ++
Sbjct: 106 RKRERWGDRDRETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDRERE 165
Query: 265 EPKIKLLKKPEKGDEKELDKR---EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKP 321
+ + + E+ +K+ + R ++ ++ +KE+ +R D + + EK
Sbjct: 166 MGETERYRDRERERQKQRETRRDRDRERQREKEDRERDR------------DRQKEREKD 213
Query: 322 KRPEDESGRDY-----REREREYERDQERIL 347
+ E E+GRD RER+RE +RD+++ +
Sbjct: 214 RYRERETGRDRDKERDRERQREKDRDRQKAI 244
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/165 (29%), Positives = 82/165 (49%), Gaps = 24/165 (14%)
Query: 317 KDEKPKRPEDESGRDYREREREYERDQERIL---RERERLKRQEEERRRQKER-YEKEKT 372
KD + ++ D + RER+R +RD++R R+RE ++EER RQ++R EK++
Sbjct: 80 KDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQRDRKREKDRE 139
Query: 373 FKR-------KEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPA 425
+R K+ E++ EKD RD+ ++ TE E+ +K+ +RDR R + R
Sbjct: 140 RQRQREIGIDKDREIETEKD--RDREREMGETERYRDRERERQKQRETRRDRDRERQR-- 195
Query: 426 MQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKEGGEE 470
+ R R+R D K + R++E+G KE E
Sbjct: 196 ----EKEDRERDR-----DRQKEREKDRYRERETGRDRDKERDRE 231
Score = 52.4 bits (124), Expect = 9e-07
Identities = 31/83 (37%), Positives = 50/83 (60%), Gaps = 5/83 (6%)
Query: 346 ILRERERLKRQEEERRRQKERY-EKEKTFKRKEEEMKK---EKDTLRDKGKKAESTESIG 401
I+RERER + +E +R+R KER+ EK++ ++ + +K E+ RD+ +K E
Sbjct: 56 IIRERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRD 115
Query: 402 SSEKTEKKEEVVK-RDRIRNKDR 423
+TE++EE + RDR R KDR
Sbjct: 116 RETETERQEERERQRDRKREKDR 138
Score = 48.9 bits (115), Expect = 1e-05
Identities = 33/146 (22%), Positives = 74/146 (50%), Gaps = 11/146 (7%)
Query: 317 KDEKPKRPEDESGRDYREREREYE----RDQERILRERERLKRQEEERRRQKERYEKEKT 372
++ + +R R RE++ E RD++R R+RER + ++ +R+R++ +T
Sbjct: 60 RERQRERERQRKRAKERHREKDREIEKDRDRQR-KRDRERQRWRDRDRKRERWGDRDRET 118
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPG 432
++EE ++++D R+K ++ + IG + E + E +DR R ++ + Y+
Sbjct: 119 ETERQEERERQRDRKREKDRERQRQREIGIDKDREIETE---KDRDREREMGETERYRDR 175
Query: 433 ARSRNRLCPPDDSTKSGDSAAERKQE 458
R R + ++ + D +R++E
Sbjct: 176 ERERQK---QRETRRDRDRERQREKE 198
Score = 47.8 bits (112), Expect = 2e-05
Identities = 46/181 (25%), Positives = 82/181 (45%), Gaps = 24/181 (13%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTST-----PETLLEEIEAKNRE 191
+K AK++ +++D ++ D R D ++ ET E E + R+
Sbjct: 70 RKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEERERQ 129
Query: 192 LIAKKTTPLLSFLKNKQRMRE-----------EKREERRRREIERKRQREEERRKWKEEE 240
K+ + +QR RE EK +R R E +R R+ ER + K+ E
Sbjct: 130 RDRKREKD-----RERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRE 184
Query: 241 KRKRKDIEKLK-KIDRIPERDKLKDEPKIKLLKKPEKGD-EKELDK-REKAKKLDKENLS 297
R+ +D E+ + K DR +RD+ K+ K + ++ D +KE D+ R++ K D++
Sbjct: 185 TRRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAI 244
Query: 298 D 298
D
Sbjct: 245 D 245
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/123 (21%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K K + ++R ++G ID D E + D E+ E + + ++ ++
Sbjct: 132 RKREKDRERQRQREIG-IDKDREIETEKDR---DREREMGETERYRDRERERQKQRETRR 187
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
+ + R R+ R++ R ++ R+R+ +R K ++ E+++ KD ++ K ID +
Sbjct: 188 DRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKERDRERQREKDRDRQKAIDCV 247
Query: 257 PER 259
P R
Sbjct: 248 PGR 250
>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
[Homo sapiens]
Length = 213
Score = 82.8 bits (203), Expect = 6e-16
Identities = 64/246 (26%), Positives = 125/246 (50%), Gaps = 35/246 (14%)
Query: 140 AKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTP 199
+K + + T+ T+D E R+ + D K + T + E ++RE
Sbjct: 3 SKTEGRHTHTETETMDRQRERRRETDR-ERDRAKESKTEDRHSERDRQRDRE-------- 53
Query: 200 LLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPER 259
+N++R R+ +RE++ RE ER+R+RE +R + +E E+ + K+ E + + ER
Sbjct: 54 -----RNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRER 108
Query: 260 DKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDE 319
K K+ ++ E+ ++E REK K++ +E +D + ++++ E +
Sbjct: 109 QKQKE-------REMERVRDRE---REKQKEMGRERQTDRETDRER---ERQAERERETG 155
Query: 320 KPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEE 379
+ ++ ED +RERERE +R++ER +ER + + ER RQ+E K + ++ E
Sbjct: 156 RERKTEDR----HRERERERKRERERKRETKERERHTDMERERQRETDRK----RDRQRE 207
Query: 380 MKKEKD 385
++E+D
Sbjct: 208 SERERD 213
Score = 82.4 bits (202), Expect = 8e-16
Identities = 64/215 (29%), Positives = 115/215 (53%), Gaps = 29/215 (13%)
Query: 215 REERRRREIERKRQR-EEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKK 273
R+ RRRE +R+R R +E + + + E+ +++D E+ ++ DR ER+K D ++
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTD-------RE 71
Query: 274 PEKGDEKELDK---REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGR 330
E+ E+E D+ RE ++ DKE +D + ++++ + +K K E E R
Sbjct: 72 GERQRERERDRDRQRETERERDKERETD-----------RHTETDRERQKQKEREMERVR 120
Query: 331 DYREREREYERDQERIL-RERERLKRQEEERRRQKERYEK-EKTFKRKEEEMKKEKDTLR 388
D RERE++ E +ER RE +R + ++ ER R+ R K E + +E E K+E++ R
Sbjct: 121 D-REREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERERKRERERKR 179
Query: 389 DKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
+ ++ T+ E+ ++E KRDR R +R
Sbjct: 180 ETKERERHTD----MERERQRETDRKRDRQRESER 210
Score = 68.9 bits (167), Expect = 9e-12
Identities = 56/212 (26%), Positives = 101/212 (47%), Gaps = 36/212 (16%)
Query: 212 EEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLL 271
E K E R R+ ERR+ E R+R ++ K DR ERD+ +D
Sbjct: 2 ESKTEGRHTHTETETMDRQRERRR---ETDRERDRAKESKTEDRHSERDRQRDR------ 52
Query: 272 KKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD 331
E+ E++ D RE+ K+ D+E ER + ++ ++E + +K + + + D
Sbjct: 53 ---ERNRERDRD-REREKQTDREG---ERQRERERDRDRQRETERERDKERETDRHTETD 105
Query: 332 YREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKG 391
RER+++ ER+ ER+ ++ ER +QKE + +T +++T R++
Sbjct: 106 -RERQKQKEREMERV---------RDREREKQKEMGRERQT----------DRETDRERE 145
Query: 392 KKAESTESIGSSEKTEKKEEVVKRDRIRNKDR 423
++AE G KTE + +R+R R ++R
Sbjct: 146 RQAERERETGRERKTEDRHRERERERKRERER 177
Score = 59.3 bits (142), Expect = 7e-09
Identities = 46/169 (27%), Positives = 79/169 (46%), Gaps = 20/169 (11%)
Query: 310 KRSDSELKDEKPKRPEDE-SGRDY---REREREYERDQERIL-----------RERERLK 354
+ +D E K + ED S RD RER RE +RD+ER RER+R +
Sbjct: 25 RETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDR 84
Query: 355 RQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK-----K 409
++E ER R KER T +E + +KE++ R + ++ E + +G +T++ +
Sbjct: 85 QRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRER 144
Query: 410 EEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
E +R+R ++R ++ R R R TK + + ++E
Sbjct: 145 ERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERE 193
Score = 48.5 bits (114), Expect = 1e-05
Identities = 34/150 (22%), Positives = 77/150 (51%), Gaps = 23/150 (15%)
Query: 333 REREREYERDQER----------------ILRERERLKRQEEERRRQKERYEKEKTFKRK 376
R+RER E D+ER R+RER + ++ +R R+K+ + + + +
Sbjct: 19 RQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRER 78
Query: 377 EEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQPGARSR 436
E + ++++T R++ K+ E T+ +++ +K++ + +R+R+++R Q R
Sbjct: 79 ERDRDRQRETERERDKERE-TDRHTETDRERQKQKEREMERVRDRER-EKQKEMGRERQT 136
Query: 437 NRLCPPDDSTKSGDSAAERKQESGISHRKE 466
+R ++ + + AER++E+G + E
Sbjct: 137 DR-----ETDRERERQAERERETGRERKTE 161
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 82.0 bits (201), Expect = 1e-15
Identities = 74/305 (24%), Positives = 153/305 (50%), Gaps = 35/305 (11%)
Query: 138 KAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEA---KNRELIA 194
KA++K KKR++ + K L+ D K+T + + A K R L
Sbjct: 2054 KASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKERRLSI 2113
Query: 195 KKTTPLLSFL----KNKQRMREEKREERRRREIERKRQR--EEERRKWKEEEKRKRKDIE 248
+++ + K + ++EK+ R++R++ K +R +E + +EE K RK E
Sbjct: 2114 EQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSE 2173
Query: 249 KLKKIDRIPERDKLKDEPKIKLLK-------------KPEKGDEKELDKREKAKKLDKE- 294
+ + E +++E I LK KP++ ++D+ E + +E
Sbjct: 2174 VILDDE---EEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEM 2230
Query: 295 -NLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERL 353
+L DE +S + + E ++E+ +R E+E + ER+ E E +++++ +E E
Sbjct: 2231 ESLLDELEKQESLS---SEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEK 2287
Query: 354 KRQEEERRRQKERYEKEKTFKRKEEEMKKEK-DTLRDKGKKAESTESIGSSEKTEKKEEV 412
K++++E++++ E EKE+ F+ KEE M +E+ ++L D + E ES E+ ++++E+
Sbjct: 2288 KKKKKEKKKE-EVQEKEEVFEEKEEIMSEEETESLSD---EEEEEESCSLEEEVDREKEI 2343
Query: 413 VKRDR 417
+K+++
Sbjct: 2344 LKKEK 2348
Score = 70.9 bits (172), Expect = 2e-12
Identities = 68/225 (30%), Positives = 108/225 (48%), Gaps = 38/225 (16%)
Query: 118 VFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKVGTIDDDPEYRKFLESY--ATDNEKMT 175
V LD++ + E PF K ++ K+++ K G D KF E +
Sbjct: 2174 VILDDEEEGGIEEEEVIPFLK--RRWRKRKEAKRG----DKPKEKFSSQVDEVESEEHFS 2227
Query: 176 STPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRK 235
E+LL+E+E K L +++ EE+REE RE E R+ EEER
Sbjct: 2228 EEMESLLDELE-KQESLSSEE---------------EEEREEEEEREEEEVREEEEER-- 2269
Query: 236 WKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKEN 295
KEEE+ + K +EK + ++ K K++ K ++ +K E +EKE E + + E+
Sbjct: 2270 -KEEEEGEEKQVEK----EEEEKKKKKKEKKKEEVQEKEEVFEEKE----EIMSEEETES 2320
Query: 296 LSDERASGQSCTLPKRSDSE---LKDEKPKRPEDESGRDYRERER 337
LSDE +SC+L + D E LK EK + +++ + R RER
Sbjct: 2321 LSDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRER 2365
Score = 63.2 bits (152), Expect = 5e-10
Identities = 81/353 (22%), Positives = 152/353 (43%), Gaps = 66/353 (18%)
Query: 124 GQEYPAIVEFAPFQKAAK--KKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETL 181
G+E E FQK+ K +K +++ KVG I E K + + E+M TL
Sbjct: 1384 GKEISKKEEKKTFQKSPKQGRKAVQKERKVGKIKR--EMTKEERDMSEEVEEMA----TL 1437
Query: 182 LEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK 241
E++ + +L+ + TP S+ K+ E K+ R+ + + E E+R +EEEK
Sbjct: 1438 EEKVVKQEGKLVMIERTP--SWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEK 1495
Query: 242 RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERA 301
+ EKL PE + L+++ K+K E+ K++ + LS
Sbjct: 1496 LHQAG-EKLS-----PEEEMLQEDKKLKW---------------EEWKQVWENMLSS--- 1531
Query: 302 SGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERR 361
K + + KDE+ E+E R+ E+E++ +Q I E + + + R
Sbjct: 1532 --------KSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRAR 1583
Query: 362 RQKERYEKEKTFKRKEEEMKKEKDTLRDKGKK---------AESTESIGSSEKTEKKEEV 412
+K+R ++E+ ++EE++ +E+ L + +K + E + K +KEE
Sbjct: 1584 AEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEET 1643
Query: 413 V---------KRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERK 456
+ + +++ K + + ++ AR +L K G AE K
Sbjct: 1644 LAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKL------AKKGGKLAEVK 1690
Score = 62.4 bits (150), Expect = 9e-10
Identities = 83/339 (24%), Positives = 156/339 (46%), Gaps = 46/339 (13%)
Query: 160 YRKFLESYATDNEKMTSTPETLLEEIEAKNREL---IAKKTTPLLSFLKNKQRMREEKRE 216
+ L S + + + TL EE+ + E + ++ + K + R+ R
Sbjct: 1525 WENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRKRARA 1584
Query: 217 ERRRREIERKRQREEER-----RKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLL 271
E++R + ERK +EEE+ R+ +EE++ + K+ + DR + + K K + L
Sbjct: 1585 EKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETL 1644
Query: 272 ----KKPEKGDEKELDKREK-AKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPED 326
+K + EK KR+K AKK +K +E+ + + L + + L + + P+
Sbjct: 1645 AQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNI-LAQKVEELPQR 1703
Query: 327 ESGRDYRERE-----------------REYERDQE--RILRERERLKRQEEERRRQKERY 367
E D++E+E +E E +QE +++ E+++L +EE Q+E+
Sbjct: 1704 EQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKL 1763
Query: 368 EKEKTFKRKEEEMK-KEKDTL-RDKGKKAESTESIGSSEK--TEKKEEVV-KRDRIRNK- 421
+E+T +EEE+ +EK+ L + K K E E +G + EKK ++ KR+R N
Sbjct: 1764 SEEETKLAQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM 1823
Query: 422 ---DRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQ 457
+ M LYQ +N + + + A+RK+
Sbjct: 1824 EELTKNKMILYQ----KKNLAQEKKNLAQEKEKLAQRKE 1858
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/291 (23%), Positives = 128/291 (43%), Gaps = 34/291 (11%)
Query: 172 EKMTSTPETLLE---EIEAKNRELIAKKTTPLLSFLKNKQRMREE-KREERRRREIERKR 227
EKMT L E+ + E + ++ FLK + R R+E KR ++ + + +
Sbjct: 2158 EKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQV 2217
Query: 228 QREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKL--------LKKPEKGDE 279
E + EE + ++EK + + E ++ ++E + + K+ E+G+E
Sbjct: 2218 DEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEE 2277
Query: 280 KELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREY 339
K+++K E+ KK K+ E + ++ + ++E ++E + E E
Sbjct: 2278 KQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEV 2337
Query: 340 ERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEK---DTLRDKGKKAES 396
+R++E IL++ ++ K QE+ R+ + R E+ + R K L+ KK S
Sbjct: 2338 DREKE-ILKKEKQFKLQEQRRKSLRGR-ERVLSILRGVPHGKGRAIRLGVLKSPLKKLMS 2395
Query: 397 TESIGSSEKT------------EKKEEVVKRDR----IRNKDRPAMQLYQP 431
T ++ EKT +KK VV+ R +K+R M Y+P
Sbjct: 2396 T-ALEMKEKTPVPVPEKQISWEDKKATVVEIPRKFLGTMDKEREVMGKYEP 2445
Score = 52.8 bits (125), Expect = 7e-07
Identities = 71/354 (20%), Positives = 143/354 (40%), Gaps = 32/354 (9%)
Query: 131 VEFAPFQKAAKKKTKK-RDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKN 189
++ A +KA + K+ + K+ ++ K + KMT + L E +
Sbjct: 1954 LDIAKEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLE 2013
Query: 190 RELIAKKTTPLL----SFLKNKQRMREEKR--EERRRREIERKRQREEERRKWKEEEKRK 243
+++ + L K K +R + +R+ + R+ ++R +E +
Sbjct: 2014 EKILLHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKL 2073
Query: 244 RKDIEKLKKIDRIPERDKLKDEPKIKLLKKP------------EKGDEKELDKREKAKKL 291
K ++ L+K+ R ER ++E K+ +K+ K D KE D EK +L
Sbjct: 2074 NKILKALQKLTR-DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSEL 2132
Query: 292 DKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE----REREYERDQERI- 346
K+ R + +R + K+EK E + R + E E E ++E +
Sbjct: 2133 TKDEKKLARKQRKLANKMRRMIN--KEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVI 2190
Query: 347 --LRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSE 404
L+ R R +++ + + KE++ + EE +E ++L D+ E ES+ S E
Sbjct: 2191 PFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDE---LEKQESLSSEE 2247
Query: 405 KTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
+ E++EE + + ++ + + G + + K + E QE
Sbjct: 2248 EEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQE 2301
Score = 49.7 bits (117), Expect = 6e-06
Identities = 60/270 (22%), Positives = 124/270 (45%), Gaps = 20/270 (7%)
Query: 165 ESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRRE-- 222
E+ A EK+ S ET L A+ EL+ ++ L ++K++M EE+ R+RE
Sbjct: 1754 EALAWQREKL-SEEETKL----AQEEELLIQEKEKLA---QHKEKMPEEEERLGRKREQL 1805
Query: 223 IERKRQREEERRKW--KEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEK 280
IE+K + ++R +W EE K K I KK + + K + K KL ++ E
Sbjct: 1806 IEKKMKLAQKRERWINSMEELTKNKMILYQKK--NLAQEKKNLAQEKEKLAQRKEN---- 1859
Query: 281 ELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYE 340
L +E+ K+ + + G + + + +L EK + + E E++
Sbjct: 1860 LLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKE--KLAETEKKLV 1917
Query: 341 RDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESI 400
+ ++ + +++E+L +++ + +K + +K + + + K+EK + + AE +
Sbjct: 1918 QVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEMKRLAEEKMRL 1977
Query: 401 GSSEKTEKKEEVVKRDRIRNKDRPAMQLYQ 430
++T K E + R R + +L++
Sbjct: 1978 VEGKETLSKGETPETSRQRKMTQVEQELFE 2007
Score = 38.5 bits (88), Expect = 0.013
Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 29/211 (13%)
Query: 215 REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKP 274
RE+ + + + +E + +E+ ++K +D+ L++ I LK K+ L+
Sbjct: 1325 REDMIQGVTQEVIRHKEVMPREEEQAQKKARDMLGLEETQVI-----LKKGKKVIFLEPG 1379
Query: 275 EKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE 334
KE+ K+E+ K K +A E K K KR + RD E
Sbjct: 1380 NVTMGKEISKKEEKKTFQKSPKQGRKA----------VQKERKVGKIKREMTKEERDMSE 1429
Query: 335 REREYERDQERILRERERL-------------KRQEEERRRQKERYEKEKTFKRK-EEEM 380
E +E+++++ +L K +E ++ E + K +K + E+ +
Sbjct: 1430 EVEEMATLEEKVVKQEGKLVMIERTPSWQDWKKAWDEWKQVHGETRKSWKAWKEEWEKRL 1489
Query: 381 KKEKDTLRDKGKKAESTESIGSSEKTEKKEE 411
+E++ L G+K E + +K K EE
Sbjct: 1490 LQEEEKLHQAGEKLSPEEEMLQEDKKLKWEE 1520
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 82.0 bits (201), Expect = 1e-15
Identities = 74/250 (29%), Positives = 134/250 (53%), Gaps = 38/250 (15%)
Query: 178 PETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKR--EERRRREIE--------RKR 227
P+ L ++ +R+ + + P S KQ++ +E ++RRR++ E RKR
Sbjct: 410 PKLLAQQHPPPDRQAVPGRPGPFPS----KQQVADEDEIWKQRRRQQSEISAAVERARKR 465
Query: 228 QREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKK---PEKGDEKELDK 284
+ EEERR EE+RK EKLK++D K+ +L+K PE+ E+E +K
Sbjct: 466 REEEERRM---EEQRKAACAEKLKRLDE-----------KLGILEKQPSPEEIREREREK 511
Query: 285 -REKAKKLDKENLSD-ERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERD 342
RE+ K+L+KE + E+ + + + EL+ E+ K+ E E R +E+E+E ER
Sbjct: 512 EREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERK-QEKEKELERQ 570
Query: 343 QERILRERERLKRQEEERRRQKERYEKEKTFKRKE---EEMKKEKDTLRDKGKKAESTES 399
+E+ +E +++K QE+E +KER + E+ + +E E M +++++ K+ E +
Sbjct: 571 KEKE-KELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFT 629
Query: 400 IGSSEKTEKK 409
S ++EK+
Sbjct: 630 RQDSNRSEKE 639
Score = 66.6 bits (161), Expect = 5e-11
Identities = 47/179 (26%), Positives = 99/179 (55%), Gaps = 6/179 (3%)
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSEL 316
P + ++ DE +I ++ ++ + +R + ++ ++E +E+ KR D +L
Sbjct: 433 PSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKL 492
Query: 317 KD-EKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKR 375
EK PE+ R+ RE+ERE E++ E+ +E+ER K +E++R RQ+E+ ++ + +
Sbjct: 493 GILEKQPSPEEIRERE-REKEREREKELEK-EQEQEREKEREKDRERQQEKEKELEKEQE 550
Query: 376 KEEEMKKEKDTLRDK--GKKAESTESIGSSEKTEKKEEVVK-RDRIRNKDRPAMQLYQP 431
K+ EM+KE+ ++K ++ E + + ++ EK+ E+ K R+++ K P +P
Sbjct: 551 KQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEP 609
Score = 37.4 bits (85), Expect = 0.030
Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 18/163 (11%)
Query: 264 DEPKIKLLKKPEKG-----DEKELDKREKAKKLDKENLSDERASGQSCTLPK-------- 310
+ P K L P++ + + KR + + DE+ S S +PK
Sbjct: 897 EAPDQKTLSAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDS 956
Query: 311 RSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKE 370
+ E +EKPK+ + + E+ Y+ E R R+EE R R
Sbjct: 957 KEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPI 1016
Query: 371 KTFKRKEEEMKKEKDTLRDK-GKKAE--STESIGSSEKTEKKE 410
K K +MK+E++ ++K G+KAE + + + EKTEKK+
Sbjct: 1017 K--KPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKD 1057
Score = 30.8 bits (68), Expect = 2.8
Identities = 29/134 (21%), Positives = 56/134 (41%), Gaps = 23/134 (17%)
Query: 139 AAKKKTKKRDTKVGTIDDDP---EYRKFLESYATDNEK-MTSTPETLLEEIEAKNRELIA 194
A +K K+ D K+G ++ P E R+ + EK + E E+ K+RE
Sbjct: 480 ACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQ 539
Query: 195 KKTTPLLSFLKNKQRMREEKREERRR-------------------REIERKRQREEERRK 235
+K L + ++ M +E+++E+ + +E E +++RE+ K
Sbjct: 540 EKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEK 599
Query: 236 WKEEEKRKRKDIEK 249
+ E +EK
Sbjct: 600 IEPREPNLEPMVEK 613
Score = 30.4 bits (67), Expect = 3.6
Identities = 47/247 (19%), Positives = 92/247 (37%), Gaps = 31/247 (12%)
Query: 207 KQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDR----------- 255
K +R+ K E +R+E E ++ + + + EK ++KD+ +
Sbjct: 1018 KPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPIQPQSVP 1077
Query: 256 ---IPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRS 312
PE +K L +KP + EK L+ + +++ ++
Sbjct: 1078 PPIQPEAEKFPSTETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMAAPVVKEEKQ 1137
Query: 313 DSEL--KDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKE 370
++ KD +RP +S ++ R + RER+ Q R + E Y +
Sbjct: 1138 PEKVISKDLVIERPRPDSRPAVKKESTLPPRTYWKEARERDWFPDQGYRGRGRGEYYSRG 1197
Query: 371 KTFK-------RKEEEMKKEKDTLRDKGKKAESTES--IGSSEKTEKKEE------VVKR 415
++++ R ++ RD +AE S + E++E + E V KR
Sbjct: 1198 RSYRGSYGGRGRGGRGHTRDYPQYRDNKPRAEHIPSGPLRQREESETRSESSDFEVVPKR 1257
Query: 416 DRIRNKD 422
R R +
Sbjct: 1258 RRQRGSE 1264
Score = 29.3 bits (64), Expect = 8.1
Identities = 42/199 (21%), Positives = 79/199 (39%), Gaps = 18/199 (9%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
Q+ K++ K R+ + + + E K E ++ E LE + K +EL K
Sbjct: 525 QEREKEREKDRERQQ---EKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMK 581
Query: 197 TTPLLSFLKNKQRMREEKREER--------RRREIERKRQREEERRKWKEEEKRKRKDIE 248
L+ ++ EEK E R ++E E +EEE +++ R K+
Sbjct: 582 EQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEAT 641
Query: 249 KLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKR--EKAKKLDKENLSDERASG-QS 305
+ + PE +P+ +L K +K L R + +++ ++ ++ G
Sbjct: 642 PVVH-ETEPESG---SQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLP 697
Query: 306 CTLPKRSDSELKDEKPKRP 324
T+P + S P RP
Sbjct: 698 QTVPSQPSSSTVPPPPHRP 716
Score = 29.3 bits (64), Expect = 8.1
Identities = 55/282 (19%), Positives = 110/282 (39%), Gaps = 41/282 (14%)
Query: 152 GTIDDDPEYRKFLESYATDN----EKMTSTPETLLEEIEAKNR----ELIAKKTTPLLSF 203
G D P+YR DN E + S P EE E ++ E++ K+ S
Sbjct: 1213 GHTRDYPQYR--------DNKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSE 1264
Query: 204 LKNKQRMREEK--REERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDK 261
+ E ++ + ++ ++ +R E ++ K K + ++ +R+ E+
Sbjct: 1265 TDTDSEIHESASDKDSLSKGKLPKREERPENKKPVKPHSSFKPDNHVRID--NRLLEKPY 1322
Query: 262 LKDEPKIK--LLKKPE-----------KGDEKELDKREKAKKLDKENLSDERASGQSCTL 308
++D+ K K L K E +G + + L + D + + + +
Sbjct: 1323 VRDDDKAKPGFLPKGEPTRRGRGGTFRRGGRDPGGRPSRPSTLRRPAYRDNQWNPRQSEV 1382
Query: 309 PKRSDSELKDEKPKRPED----ESGRDYREREREYERDQERILRERERLKRQEEERRRQK 364
PK D E P+R E + + + ER+++ +ER R+R ++++ R +
Sbjct: 1383 PKPEDGE----PPRRHEQFIPIAADKRPPKFERKFDPARERPRRQRPTRPPRQDKPPRFR 1438
Query: 365 ERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKT 406
E+E K E T+ + ++ +T S KT
Sbjct: 1439 RLREREAASKSNEVVAVPTNGTVNNVAQEPVNTLGDISGNKT 1480
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 81.3 bits (199), Expect = 2e-15
Identities = 66/258 (25%), Positives = 130/258 (50%), Gaps = 32/258 (12%)
Query: 172 EKMTSTPETLLEEIEAKNRELIAK-KTTPLLSFLKNKQRMREEKREERRRREIERKRQRE 230
E++ L +E+E+ R+L A+ + +LS L +Q R ++EER R + ER R++E
Sbjct: 160 EQLQDETNHLRKELESVGRQLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQE 219
Query: 231 EERRKWKEEEKRKRKDIEKLKKID-RIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAK 289
E + E+E+R R+ E+L++ + R+ E+++ E + +L ++ E+ E+E RE+ +
Sbjct: 220 E---RLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEE 276
Query: 290 KLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILRE 349
+L ++ +ER Q L RE+E +ER+ +
Sbjct: 277 RLHEQ---EERLCEQEERL------------------------REQEERLCEQEERLREQ 309
Query: 350 RERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKK 409
ERL QEE R Q+ER +++ +E +++ + L + ++ E + E+
Sbjct: 310 EERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEV 369
Query: 410 EEVVKRDRIRNKDRPAMQ 427
EE+++++R+R +D Q
Sbjct: 370 EELLEQERLRQQDERLWQ 387
Score = 37.4 bits (85), Expect = 0.030
Identities = 42/179 (23%), Positives = 87/179 (48%), Gaps = 20/179 (11%)
Query: 287 KAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPK-RPEDESGRDYREREREYERDQER 345
K K E L+ E +G S +L+DE R E ES + E E +
Sbjct: 139 KLKNQTAEPLAPEPPAGPSKV------EQLQDETNHLRKELESVGRQLQAEVENNQMLSL 192
Query: 346 ILRERERLKRQEEERRRQKER--YEKEKTFKRKEEEMKKEKDTLRDKGKK-AESTESIGS 402
+ R +E R++EER R++E E+E+ +EE ++++++ LR++ ++ E E +
Sbjct: 193 LNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLRE 252
Query: 403 SEK--TEKKEEVVKR-DRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQE 458
E+ E++E + ++ +R+R ++ +L++ RLC ++ + + ++E
Sbjct: 253 HEERLCEQEERLCEQEERLREQEE---RLHE----QEERLCEQEERLREQEERLCEQEE 304
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 81.3 bits (199), Expect = 2e-15
Identities = 59/227 (25%), Positives = 129/227 (56%), Gaps = 20/227 (8%)
Query: 207 KQRMREEK--REERRRREIERKRQREEERRKWKEEEK------RKRKDIEKL-KKIDRIP 257
K R +EEK R+E + E E K RE+E + W++EEK + R+ EK+ ++ ++I
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKI-REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 258 ERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKE-NLSDERASGQSCTLPKRSDSEL 316
E+D+ E + ++ ++ EK E+E ++EK + +K+ DE+ Q + ++ +
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 317 KDEKPKRPEDESGRDYRER----EREYERDQERILRERERLKRQEEERRRQKERYEKEKT 372
+ E+ + ++E R+ E+ E + + +E+I R+ E+++ QEE+ RQ++ ++E+
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIR 419
+EE+M ++++ + ++ +K + E EK +++EE ++ +R
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQE-----EKMQRQEEKMREQEVR 539
Score = 79.3 bits (194), Expect = 7e-15
Identities = 63/313 (20%), Positives = 153/313 (48%), Gaps = 20/313 (6%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K R+ + + + + E +KM E + E+ E K RE K
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ-EEKIREQEEKM 369
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
+ ++++E++ E R+ E R+++ + + + W++E+K + +D EK+++
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD-EKIRE---- 424
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSD--ERASGQSCTLPKRSDS 314
E + + E KI+ L++ + E++L + E+ + ++E + + E+ Q + ++ +
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 315 ELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKER-------- 366
+ EK + E++ E+E + R +E++ + E+++ QEE+ +RQ+E+
Sbjct: 485 TWRQEKLLKQEEKIW----EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 367 YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAM 426
+++E+ + +E +++ ++ L G+KAE G +++ + ++ K + A
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Query: 427 QLYQPGARSRNRL 439
L Q R L
Sbjct: 601 SLQQQQDHYRGHL 613
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/248 (25%), Positives = 134/248 (54%), Gaps = 27/248 (10%)
Query: 179 ETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERK------RQREEE 232
+ L +E+++ + +L A+ L L N+Q+ + R+E + +E E K + RE+E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 233 RRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD 292
+ W++EEK ++ + ++ D++ +++ E + K+ ++ EK +E RE+ +K+
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 293 KEN----LSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR 348
++ +E+ Q KR + + EK R +DE RE+E E R +E+I
Sbjct: 385 EQEEEMWRQEEKIREQE---EKRQEKMWRQEKKMREQDEK---IREQEEEMWRQEEKIRE 438
Query: 349 ERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK 408
E ++ QEE+ R +E+ ++E EE+M+++++ ++ + +K + E EKT +
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEE------EEKMQEQEEKIQRQEEKIQEQE-----EKTWR 487
Query: 409 KEEVVKRD 416
+E+++K++
Sbjct: 488 QEKLLKQE 495
Score = 57.0 bits (136), Expect = 4e-08
Identities = 61/294 (20%), Positives = 137/294 (46%), Gaps = 22/294 (7%)
Query: 191 ELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKL 250
+L ++ P L +N + +E+ +E+ E+ R E E+ + + K ++ +E+
Sbjct: 194 KLTKERDAPSLELYRNT--ITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERA 251
Query: 251 KKIDRIP------ERDKLKDEPKIKLLKKPEKGDEKEL------DKREKA-KKLDKENLS 297
+ + +P E D+L E + K + +E EL + EK ++ +K
Sbjct: 252 QLL--LPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQ 309
Query: 298 DERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRE---REREYERDQERILRERE-RL 353
+E+ Q + ++ + + E+ ++E R+ + R+ E R+QE +RE+E ++
Sbjct: 310 EEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKM 369
Query: 354 KRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEV 412
RQEE+ R Q E+ E+E+ R+EE+++++++ ++K + E + E++EE+
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429
Query: 413 VKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHRKE 466
+++ + MQ + R ++ ++QE I ++E
Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Score = 55.8 bits (133), Expect = 8e-08
Identities = 48/234 (20%), Positives = 115/234 (49%), Gaps = 14/234 (5%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+KK +++D K+ +++ +R+ E + E+M E L E+E K +E K
Sbjct: 412 EKKMREQDEKIREQEEEM-WRQ--EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQR--EEERRKWKEEEKRKRKDIEKLKKIDRIPE 258
+ +++++E++ + R+ ++ ++ ++ E+E + W++EEK ++ + ++ +++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 259 RDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE------RASGQS--CTLPK 310
+++ E +++L ++ EK E+E+ +E ++L K E R SG TL
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP 588
Query: 311 RSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQK 364
ELK ++ + + + YR ++Y +++ +E L + R K
Sbjct: 589 ILQVELKSQEAQSLQQQQDH-YRGHLQQYVAAYQQLASGKEALPSCSSRKLRAK 641
Score = 33.9 bits (76), Expect = 0.33
Identities = 47/225 (20%), Positives = 89/225 (39%), Gaps = 20/225 (8%)
Query: 223 IERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKEL 282
I + Q+ + R K + + K EK ++ E + + K + K+ ++ D+ E
Sbjct: 36 INKLEQQSKVRNKGHGKPREKSIADEKFFQLS---EMEAYLENRKRRGTKRWDEDDDLEE 92
Query: 283 DK-----REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER 337
+ +E K++ DE + K++ E+K KR E + ++Y R+R
Sbjct: 93 SEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKR 152
Query: 338 EYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKD---------TLR 388
+ L E KR E + ++ E++ KE+D T+
Sbjct: 153 VVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDAPSLELYRNTIT 212
Query: 389 D---KGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAMQLYQ 430
D K K AE E + E + + ++ +D R +R + L Q
Sbjct: 213 DEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQ 257
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 81.3 bits (199), Expect = 2e-15
Identities = 59/227 (25%), Positives = 129/227 (56%), Gaps = 20/227 (8%)
Query: 207 KQRMREEK--REERRRREIERKRQREEERRKWKEEEK------RKRKDIEKL-KKIDRIP 257
K R +EEK R+E + E E K RE+E + W++EEK + R+ EK+ ++ ++I
Sbjct: 319 KIREQEEKMWRQEEKMHEQEEKI-REQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 258 ERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKE-NLSDERASGQSCTLPKRSDSEL 316
E+D+ E + ++ ++ EK E+E ++EK + +K+ DE+ Q + ++ +
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIR 437
Query: 317 KDEKPKRPEDESGRDYRER----EREYERDQERILRERERLKRQEEERRRQKERYEKEKT 372
+ E+ + ++E R+ E+ E + + +E+I R+ E+++ QEE+ RQ++ ++E+
Sbjct: 438 ELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEK 497
Query: 373 FKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIR 419
+EE+M ++++ + ++ +K + E EK +++EE ++ +R
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQE-----EKMQRQEEKMREQEVR 539
Score = 79.3 bits (194), Expect = 7e-15
Identities = 63/313 (20%), Positives = 153/313 (48%), Gaps = 20/313 (6%)
Query: 137 QKAAKKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKK 196
+K +++ K R+ + + + + E +KM E + E+ E K RE K
Sbjct: 311 EKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ-EEKIREQEEKM 369
Query: 197 TTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEKRKRKDIEKLKKIDRI 256
+ ++++E++ E R+ E R+++ + + + W++E+K + +D EK+++
Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD-EKIRE---- 424
Query: 257 PERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSD--ERASGQSCTLPKRSDS 314
E + + E KI+ L++ + E++L + E+ + ++E + + E+ Q + ++ +
Sbjct: 425 QEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEK 484
Query: 315 ELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKER-------- 366
+ EK + E++ E+E + R +E++ + E+++ QEE+ +RQ+E+
Sbjct: 485 TWRQEKLLKQEEKIW----EQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRL 540
Query: 367 YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNKDRPAM 426
+++E+ + +E +++ ++ L G+KAE G +++ + ++ K + A
Sbjct: 541 WQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQ 600
Query: 427 QLYQPGARSRNRL 439
L Q R L
Sbjct: 601 SLQQQQDHYRGHL 613
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/248 (25%), Positives = 134/248 (54%), Gaps = 27/248 (10%)
Query: 179 ETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERK------RQREEE 232
+ L +E+++ + +L A+ L L N+Q+ + R+E + +E E K + RE+E
Sbjct: 265 DRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQE 324
Query: 233 RRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLD 292
+ W++EEK ++ + ++ D++ +++ E + K+ ++ EK +E RE+ +K+
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 293 KEN----LSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQERILR 348
++ +E+ Q KR + + EK R +DE RE+E E R +E+I
Sbjct: 385 EQEEEMWRQEEKIREQE---EKRQEKMWRQEKKMREQDEK---IREQEEEMWRQEEKIRE 438
Query: 349 ERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK 408
E ++ QEE+ R +E+ ++E EE+M+++++ ++ + +K + E EKT +
Sbjct: 439 LEEMMQDQEEKLREVEEKMQEE------EEKMQEQEEKIQRQEEKIQEQE-----EKTWR 487
Query: 409 KEEVVKRD 416
+E+++K++
Sbjct: 488 QEKLLKQE 495
Score = 55.8 bits (133), Expect = 8e-08
Identities = 65/302 (21%), Positives = 142/302 (47%), Gaps = 50/302 (16%)
Query: 183 EEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRR--REIERKRQREE---ERRKWK 237
EE++ KN EL + K R+ E ++ E + ++++RK +R + +++ +
Sbjct: 214 EELKEKNAEL------------QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQ 261
Query: 238 EEEKRKRKDIEKLK-KIDRIPERDKL------KDEPKI-----KLLKKPEKGDEKELDKR 285
E R K+++ + K+ E ++L + E K+ K+ ++ EK E+EL R
Sbjct: 262 VEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR 321
Query: 286 EKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYREREREYERDQER 345
E+ +K+ ++ +E+ Q +EK + ED+ R +E + +E+
Sbjct: 322 EQEEKMWRQ---EEKMHEQ-------------EEKIREQEDKMWR----QEEKIREQEEK 361
Query: 346 ILRERERLKRQEEERRRQKER-YEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSE 404
I + E++ RQEE+ R Q E+ E+E+ R+EE+++++++ ++K + E +
Sbjct: 362 IREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEK 421
Query: 405 KTEKKEEVVKRDRIRNKDRPAMQLYQPGARSRNRLCPPDDSTKSGDSAAERKQESGISHR 464
E++EE+ +++ + MQ + R ++ ++QE I +
Sbjct: 422 IREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQ 481
Query: 465 KE 466
+E
Sbjct: 482 EE 483
Score = 55.8 bits (133), Expect = 8e-08
Identities = 48/234 (20%), Positives = 115/234 (49%), Gaps = 14/234 (5%)
Query: 141 KKKTKKRDTKVGTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPL 200
+KK +++D K+ +++ +R+ E + E+M E L E+E K +E K
Sbjct: 412 EKKMREQDEKIREQEEEM-WRQ--EEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQE 468
Query: 201 LSFLKNKQRMREEKREERRRREIERKRQR--EEERRKWKEEEKRKRKDIEKLKKIDRIPE 258
+ +++++E++ + R+ ++ ++ ++ E+E + W++EEK ++ + ++ +++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQR 528
Query: 259 RDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDE------RASGQS--CTLPK 310
+++ E +++L ++ EK E+E+ +E ++L K E R SG TL
Sbjct: 529 QEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTP 588
Query: 311 RSDSELKDEKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQK 364
ELK ++ + + + YR ++Y +++ +E L + R K
Sbjct: 589 ILQVELKSQEAQSLQQQQDH-YRGHLQQYVAAYQQLASGKEALPSCSSRKLRAK 641
Score = 35.0 bits (79), Expect = 0.15
Identities = 43/211 (20%), Positives = 86/211 (40%), Gaps = 12/211 (5%)
Query: 223 IERKRQREEERRKWKEEEKRKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKEL 282
I + Q+ + R K + + K EK ++ E + + K + K+ ++ D+ E
Sbjct: 36 INKLEQQSKVRNKGHGKPREKSIADEKFFQLS---EMEAYLENRKRRGTKRWDEDDDLEE 92
Query: 283 DK-----REKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRDYRERER 337
+ +E K++ DE + K++ E+K KR E + ++Y R+R
Sbjct: 93 SEDSKQCKESLKRVTFTLPDDEAIEDAGVSHVKKNSDEVKSSFKKRQEKMNEKNYTFRKR 152
Query: 338 EYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAEST 397
+ L E KR E + ++ E++ KE+D L + +
Sbjct: 153 VVIKKPWLRLGEVTAQKRPENSLLEETLHFDHAVRMGTYIEKLTKERDALSLELYR---- 208
Query: 398 ESIGSSEKTEKKEEVVKRDRIRNKDRPAMQL 428
+I E EK E+ ++ R+ ++ +QL
Sbjct: 209 NTITDEELKEKNAELQEKLRLVESEKSEIQL 239
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.128 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,124,571
Number of Sequences: 37866
Number of extensions: 1113687
Number of successful extensions: 49225
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 912
Number of HSP's successfully gapped in prelim test: 1377
Number of HSP's that attempted gapping in prelim test: 9130
Number of HSP's gapped (non-prelim): 12883
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.