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Search of human proteins with 4504805
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504805 basic leucine zipper nuclear factor 1 [Homo sapiens]
(400 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504805 basic leucine zipper nuclear factor 1 [Homo sapiens] 790 0.0
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 47 2e-05
gi|221219020 NYD-SP11 protein [Homo sapiens] 46 5e-05
gi|31982906 cingulin-like 1 [Homo sapiens] 46 5e-05
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 46 5e-05
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap... 45 1e-04
gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C... 45 1e-04
gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo sapi... 45 1e-04
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 45 2e-04
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 44 3e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 44 3e-04
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 44 3e-04
gi|58530840 desmoplakin isoform I [Homo sapiens] 44 3e-04
gi|56550047 uveal autoantigen with coiled-coil domains and ankyr... 44 3e-04
gi|59850762 uveal autoantigen with coiled-coil domains and ankyr... 44 3e-04
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens] 43 4e-04
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens] 43 4e-04
gi|169208458 PREDICTED: similar to golgi autoantigen, golgin sub... 42 8e-04
gi|154937324 hypothetical protein LOC440295 [Homo sapiens] 42 8e-04
gi|94721321 coiled-coil domain containing 11 [Homo sapiens] 42 0.001
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 42 0.001
gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo sap... 42 0.001
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 41 0.002
gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo ... 41 0.002
gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo sa... 41 0.002
gi|115527097 CDC42-binding protein kinase beta [Homo sapiens] 41 0.002
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 40 0.003
gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens] 40 0.003
gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens] 40 0.003
gi|114155142 nuclear pore complex-associated protein TPR [Homo s... 40 0.004
>gi|4504805 basic leucine zipper nuclear factor 1 [Homo sapiens]
Length = 400
Score = 790 bits (2039), Expect = 0.0
Identities = 400/400 (100%), Positives = 400/400 (100%)
Query: 1 MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESP 60
MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESP
Sbjct: 1 MTTKNLETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESP 60
Query: 61 GVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPN 120
GVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPN
Sbjct: 61 GVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPN 120
Query: 121 KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL 180
KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL
Sbjct: 121 KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL 180
Query: 181 AREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQN 240
AREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQN
Sbjct: 181 AREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQN 240
Query: 241 RDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNH 300
RDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNH
Sbjct: 241 RDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNH 300
Query: 301 KLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFE 360
KLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFE
Sbjct: 301 KLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDPVTCKESSPDNPFFE 360
Query: 361 SSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL 400
SSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL
Sbjct: 361 SSPTTLLATKKNIGRFHPYTRYENITFNCCNHCRGELIAL 400
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 47.4 bits (111), Expect = 2e-05
Identities = 41/168 (24%), Positives = 76/168 (45%), Gaps = 24/168 (14%)
Query: 124 SEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLARE 183
++ K +KLK+ E +LQ +E L++ R + +E D+L A
Sbjct: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQER---------DELADEITNSASG 1723
Query: 184 KNQLILENEALGRNTAQLSEQLE--------------RMSIQCDVWRSKFLASRVMADEL 229
K+ L+ E L AQL E+LE + ++Q D ++ A R A +
Sbjct: 1724 KSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKS 1783
Query: 230 TNSRAALQRQNRDAHGAIQDLL-SEREQFRQEMIATQKLLEELLVSLQ 276
N+R L+RQN++ +Q+L + + +F+ + A + + +L L+
Sbjct: 1784 DNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLE 1831
Score = 44.7 bits (104), Expect = 2e-04
Identities = 37/188 (19%), Positives = 91/188 (48%), Gaps = 22/188 (11%)
Query: 108 EFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQL--------RVQTEVNR 159
+ L + + K++ + +E L+ ++++LL+D E LS +L +++ NR
Sbjct: 1365 QVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNR 1424
Query: 160 ELKKLLVASVGDDLQY----HFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVW 215
++L +V D Q + E+ ++ +QL+ E +++ +A+ +E+ +R +
Sbjct: 1425 LQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSI---SARYAEERDRAEAEAREK 1481
Query: 216 RSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSERE-------QFRQEMIATQKLL 268
+K L+ +E ++ +RQN+ ++DL+S ++ + + A ++ +
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541
Query: 269 EELLVSLQ 276
EE+ L+
Sbjct: 1542 EEMRTQLE 1549
Score = 30.4 bits (67), Expect = 3.0
Identities = 34/152 (22%), Positives = 67/152 (44%), Gaps = 19/152 (12%)
Query: 120 NKELSEVKNVLEKLKNSERRLLQDKEGLSNQLR-VQTEVNRELK---KLLVASVGDDLQY 175
N EL+ ++ +K N+ ++L + + L +L+ ++ V + K L A +G L+
Sbjct: 1770 NAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQ-LEE 1828
Query: 176 HFERLAREK--------------NQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLA 221
E+ A+E+ ++ ++ E R+ Q EQ+E+ + + + +
Sbjct: 1829 QLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEE 1888
Query: 222 SRVMADELTNSRAALQRQNRDAHGAIQDLLSE 253
+ A SR LQR+ DA A + L E
Sbjct: 1889 AEEEATRANASRRKLQRELDDATEANEGLSRE 1920
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 46.2 bits (108), Expect = 5e-05
Identities = 64/304 (21%), Positives = 122/304 (40%), Gaps = 45/304 (14%)
Query: 41 SRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVK 100
++K L W+K E + GK+ K + + V L + N + + K
Sbjct: 1659 AQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQ------NLDWQEK 1712
Query: 101 SLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRE 160
L E E + +EL++ + KL +++L +++E L+ Q +E +
Sbjct: 1713 ELAQELEELEWDMEELSWKEEELNQEEG---KLVEEKKKLAEEEEALAWQREKLSEEETK 1769
Query: 161 LKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFL 220
L A + L E+LA+ K ++ E E LGR QL E+ +++ + + W +
Sbjct: 1770 L-----AQEEELLIQEKEKLAQHKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSM- 1823
Query: 221 ASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGRE 280
+ELT ++ L ++ ++L E++ QE + E LL
Sbjct: 1824 ------EELTKNKMILYQK--------KNLAQEKKNLAQEKEKLAQRKENLL-------- 1861
Query: 281 QTYSPSVQPHSTAELALTNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETV 340
Y+ HS +L +KL + + ++K+ E EK+AET
Sbjct: 1862 --YNKERLTHSKKQLVQVKNKLG------MFNKILAQVEEKLTQEKETVIKKKEKLAETE 1913
Query: 341 LRIL 344
+++
Sbjct: 1914 KKLV 1917
Score = 43.1 bits (100), Expect = 4e-04
Identities = 56/277 (20%), Positives = 112/277 (40%), Gaps = 32/277 (11%)
Query: 131 EKLKNSERRLLQDKEGLSNQLRVQTEVNREL---------KKLLVASVGDDLQYHFERLA 181
EKL ER+L Q++ L+ T+ +RE+ K+ +A G+ L E+LA
Sbjct: 1600 EKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLA 1659
Query: 182 REKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNR 241
+++ +L + E + R +L+++ +++ ++ K L L ++
Sbjct: 1660 QKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELE 1719
Query: 242 DAHGAIQDLLSEREQFRQE---MIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELAL- 297
+ +++L + E+ QE ++ +K L E +L W RE+ + EL +
Sbjct: 1720 ELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQ 1779
Query: 298 TNHKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILDP----VTCKESS 353
KLA+ +++K+P E E++ E +++ + E
Sbjct: 1780 EKEKLAQ-------------HKEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEEL 1826
Query: 354 PDNPFFESSPTTLLATKKNIGRFHP--YTRYENITFN 388
N L KKN+ + R EN+ +N
Sbjct: 1827 TKNKMILYQKKNLAQEKKNLAQEKEKLAQRKENLLYN 1863
Score = 37.7 bits (86), Expect = 0.019
Identities = 59/293 (20%), Positives = 107/293 (36%), Gaps = 73/293 (24%)
Query: 52 KKAVPSESPGVLQLGKMLTEKAMEVKAVR---------------ILVPKAAITHDIPNKN 96
K+ +P E + + + L EK M++ R IL K + + N
Sbjct: 1788 KEKMPEEEERLGRKREQLIEKKMKLAQKRERWINSMEELTKNKMILYQKKNLAQEKKNLA 1847
Query: 97 TKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVL-------------------------E 131
+ + L K L E + K+L +VKN L E
Sbjct: 1848 QEKEKLAQRKENLLYNKERLTHSKKQLVQVKNKLGMFNKILAQVEEKLTQEKETVIKKKE 1907
Query: 132 KLKNSERRLLQDKEGLSNQLR--VQTEVNRELKKLLV------------ASVGDDLQYHF 177
KL +E++L+Q ++ L+ + Q ++ L+K +V A L
Sbjct: 1908 KLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIAKEEKALNLEM 1967
Query: 178 ERLAREKNQLILENEALGR-NTAQLSEQLERMSIQCDVWRSKF-LASRVMAD-------- 227
+RLA EK +L+ E L + T + S Q + ++ +++ K L +++
Sbjct: 1968 KRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKILLHEDRILAME 2027
Query: 228 ---------ELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
E T + + R A + L+ +RE +E K+L+ L
Sbjct: 2028 ESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKILKAL 2080
Score = 30.0 bits (66), Expect = 3.9
Identities = 22/109 (20%), Positives = 52/109 (47%), Gaps = 5/109 (4%)
Query: 100 KSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNR 159
+ L + + + E + + +L+++ L+KL ER+L Q++ ++ R R
Sbjct: 2050 RKLAKASRKLIKKRESLSKEPAKLNKILKALQKLTRDERKLTQEEIKMTKMKRALFVKER 2109
Query: 160 ELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERM 208
L + S D ++ F + ++++L + + L R +L+ ++ RM
Sbjct: 2110 RLS--IEQSKLDIKEWDF---SEKRSELTKDEKKLARKQRKLANKMRRM 2153
>gi|31982906 cingulin-like 1 [Homo sapiens]
Length = 1302
Score = 46.2 bits (108), Expect = 5e-05
Identities = 49/190 (25%), Positives = 85/190 (44%), Gaps = 19/190 (10%)
Query: 121 KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL 180
K E++ + E+L++ +R QD+ QL QT + E + + + DD +++
Sbjct: 1009 KMQDEMRLMEEELRDYQRA--QDEALTKRQLLEQTLKDLEYELEAKSHLKDDRSRLVKQM 1066
Query: 181 AREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQN 240
+ +QL +E E N+ LSE++ R Q + R++ L R +L + +L+RQN
Sbjct: 1067 EDKVSQLEMELEEERNNSDLLSERISRSREQMEQLRNELLQERAARQDLECDKISLERQN 1126
Query: 241 RDAHGAIQDL----LSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAELA 296
+D I L S +E +M A LE+ L S + A L
Sbjct: 1127 KDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLES-------------EERDRANLQ 1173
Query: 297 LTNHKLAKAV 306
L+N +L + V
Sbjct: 1174 LSNRRLERKV 1183
Score = 32.0 bits (71), Expect = 1.0
Identities = 36/176 (20%), Positives = 72/176 (40%), Gaps = 34/176 (19%)
Query: 113 SEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGD- 171
SE + +++ +++N L + + + + L DK L Q N++LK ++ G
Sbjct: 1088 SERISRSREQMEQLRNELLQERAARQDLECDKISLERQ-------NKDLKSRIIHLEGSY 1140
Query: 172 ----------------DLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVW 215
+L+ E R++ L L N L R +L Q++
Sbjct: 1141 RSSKEGLVVQMEARIAELEDRLESEERDRANLQLSNRRLERKVKELVMQVD--------- 1191
Query: 216 RSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
+ L+ D+L+ A++RQ +A I L S +++ ++E+ + E L
Sbjct: 1192 -DEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSKKKLQRELEEQMDMNEHL 1246
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 46.2 bits (108), Expect = 5e-05
Identities = 62/274 (22%), Positives = 117/274 (42%), Gaps = 44/274 (16%)
Query: 38 GVQSRKHHSLQSPWKKAVPSESPGVLQLGKM-LTEKAMEVKAVRILVP-----KAAITHD 91
G + + H LQ +A ++ L+LG+ +TEK ++ V+ L+ K +
Sbjct: 1604 GHKKEELHLLQGSMVQA-KADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQ 1662
Query: 92 IPNKNTKVKSLGHHKGEFLGQSEGVI----EPNKELSEVKNVLEKLKNSERRL----LQD 143
I + T++ + K E + E + + +K +E+KN+L+ L+ L LQ
Sbjct: 1663 ISERKTQLTLI---KQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQH 1719
Query: 144 KEGLSNQLRVQTEVNRELKKL-----LVASVGDDLQYHFERLAREKNQL---ILENEALG 195
+ +S + Q V E +L + ++++ + L R+K ++ E+ AL
Sbjct: 1720 DQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQ 1779
Query: 196 RNTAQLSEQLERMSIQCDVWRSKFL-ASRVMADELTNSR-----------------AALQ 237
LS++ E + +CD+W K RV+A NS+ L
Sbjct: 1780 SCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELD 1839
Query: 238 RQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
+ NRD D+ + ++Q +++ A L EEL
Sbjct: 1840 QLNRDKLSLHNDISAMQQQLQEKREAVNSLQEEL 1873
Score = 31.6 bits (70), Expect = 1.3
Identities = 44/209 (21%), Positives = 87/209 (41%), Gaps = 15/209 (7%)
Query: 63 LQLGKMLTE---KAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEP 119
LQ+ K E K E+K ++I I + ++K H K + G+ + +
Sbjct: 517 LQMEKQKQEIAGKQKEIKDLQIA---------IDSLDSKDPKHSHMKAQKSGKEQQLDIM 567
Query: 120 NKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRV-QTEVNRELKKLLVASVGDDLQYHFE 178
NK+ ++++ L+++ + + ++ + L QL Q N LKK L + LQ +
Sbjct: 568 NKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISG-LQEYLG 626
Query: 179 RLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQR 238
+ + Q E L L ++L + + D + + M EL +ALQ
Sbjct: 627 TIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQE 686
Query: 239 QNRDAHGAIQDLLSEREQFRQEMIATQKL 267
Q+ + + ++Q + + E+ A L
Sbjct: 687 QH-EVNASLQQTQGDLSAYEAELEARLNL 714
Score = 31.2 bits (69), Expect = 1.7
Identities = 42/229 (18%), Positives = 87/229 (37%), Gaps = 24/229 (10%)
Query: 106 KGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLL 165
KGE Q + + +E+ + L++ L ++KE L + + + + K++L
Sbjct: 1751 KGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVL 1810
Query: 166 VASVGDD----------------LQYHFERLAREKNQLILENEALGRNTAQ-------LS 202
A+ + LQ ++L R+K L + A+ + + L
Sbjct: 1811 AAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQ 1870
Query: 203 EQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMI 262
E+L + ++ + L + D L + + LQ+ + +D E E +Q++
Sbjct: 1871 EELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQ 1930
Query: 263 ATQKLLEELLVSLQWGREQTYSPSVQPHSTAELALTNHKLAKAVNSHLL 311
Q +EE + L +E + + + E L K+ H L
Sbjct: 1931 VLQNEIEENKLKLV-QQEMMFQRLQKERESEESKLETSKVTLKEQQHQL 1978
Score = 30.8 bits (68), Expect = 2.3
Identities = 30/114 (26%), Positives = 60/114 (52%), Gaps = 20/114 (17%)
Query: 110 LGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQ---DKEGLSNQLRVQTEVN-----REL 161
L ++E + KE + KN +EK +++R LLQ D E L + + +T VN ++L
Sbjct: 1442 LAEAESELSCTKE--KTKNAVEKFTDAKRSLLQTESDAEELERRAQ-ETAVNLVKADQQL 1498
Query: 162 KKLLVASVGDDLQYH---FERLAREKNQLILENEA----LGRNTAQLSEQLERM 208
+ L + DL+ H E + +E N+++ ++ L + +L+E+L+++
Sbjct: 1499 RSL--QADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKL 1550
>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
sapiens]
Length = 693
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/199 (27%), Positives = 81/199 (40%), Gaps = 37/199 (18%)
Query: 126 VKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKN 185
V +V+E+L++ + L Q+ EGL +L+ Q E N+ L LL LQ E L ++
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALS-LLSKEQKQRLQEQEEMLREQEA 351
Query: 186 QLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHG 245
Q + E E +L EQ ER L + LQ Q
Sbjct: 352 QRVREQE-------RLCEQNER---------------------LREQQKTLQEQGERLRK 383
Query: 246 AIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAE--LALT-NHKL 302
Q L + E+ R+E QK + L W +E+ + E LAL+ NHKL
Sbjct: 384 QEQRLRKQEERLRKEEERLQKQEKRL-----WDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 303 AKAVNSHLLGNVGINNQKK 321
K + +NN+KK
Sbjct: 439 DKQLAEPQCSFEDLNNEKK 457
Score = 35.0 bits (79), Expect = 0.12
Identities = 49/231 (21%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Query: 62 VLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
+ +L + L+E ++ L P A +T + + K L G+ + +E N+
Sbjct: 268 IQELERSLSELKNQMAEPPSLAPPA-VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 122 ELSEV-KNVLEKLKNSER--------------RLLQDKEGLSNQLRVQTEVNRELKKL-- 164
LS + K ++L+ E RL + E L Q + E L+K
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 165 LVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLAS-R 223
+ + L+ ERL +++ +L + E L + +L +Q ER+++ + K LA +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQ 446
Query: 224 VMADELTNSRAA---LQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
++L N + + L++Q ++ + + E R + + TQ L L
Sbjct: 447 CSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVAL 497
>gi|51472437 PREDICTED: golgi autoantigen, golgin subfamily a, 6C
isoform 1 [Homo sapiens]
Length = 693
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/199 (27%), Positives = 81/199 (40%), Gaps = 37/199 (18%)
Query: 126 VKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKN 185
V +V+E+L++ + L Q+ EGL +L+ Q E N+ L LL LQ E L ++
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALS-LLSKEQKQRLQEQEEMLREQEA 351
Query: 186 QLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHG 245
Q + E E +L EQ ER L + LQ Q
Sbjct: 352 QRVREQE-------RLCEQNER---------------------LREQQKTLQEQGERLRK 383
Query: 246 AIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAE--LALT-NHKL 302
Q L + E+ R+E QK + L W +E+ + E LAL+ NHKL
Sbjct: 384 QEQRLRKQEERLRKEEERLQKQEKRL-----WDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 303 AKAVNSHLLGNVGINNQKK 321
K + +NN+KK
Sbjct: 439 DKQLAEPQCSFEDLNNEKK 457
Score = 35.0 bits (79), Expect = 0.12
Identities = 49/231 (21%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Query: 62 VLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
+ +L + L+E ++ L P A +T + + K L G+ + +E N+
Sbjct: 268 IQELERSLSELKNQMAEPPSLAPPA-VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 122 ELSEV-KNVLEKLKNSER--------------RLLQDKEGLSNQLRVQTEVNRELKKL-- 164
LS + K ++L+ E RL + E L Q + E L+K
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 165 LVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLAS-R 223
+ + L+ ERL +++ +L + E L + +L +Q ER+++ + K LA +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQ 446
Query: 224 VMADELTNSRAA---LQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
++L N + + L++Q ++ + + E R + + TQ L L
Sbjct: 447 CSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVAL 497
>gi|146133848 golgi autoantigen, golgin subfamily a, 6 [Homo
sapiens]
Length = 693
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/199 (27%), Positives = 81/199 (40%), Gaps = 37/199 (18%)
Query: 126 VKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKN 185
V +V+E+L++ + L Q+ EGL +L+ Q E N+ L LL LQ E L ++
Sbjct: 293 VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQALS-LLSKEQKQRLQEQEEMLREQEA 351
Query: 186 QLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHG 245
Q + E E +L EQ ER L + LQ Q
Sbjct: 352 QRVREQE-------RLCEQNER---------------------LREQQKTLQEQGERLRK 383
Query: 246 AIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHSTAE--LALT-NHKL 302
Q L + E+ R+E QK + L W +E+ + E LAL+ NHKL
Sbjct: 384 QEQRLRKQEERLRKEEERLQKQEKRL-----WDQEERLWKKEERLQKQEERLALSQNHKL 438
Query: 303 AKAVNSHLLGNVGINNQKK 321
K + +NN+KK
Sbjct: 439 DKQLAEPQCSFEDLNNEKK 457
Score = 34.3 bits (77), Expect = 0.20
Identities = 48/231 (20%), Positives = 97/231 (41%), Gaps = 22/231 (9%)
Query: 62 VLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
+ +L + L+E ++ L P A +T + + K L G+ + +E N+
Sbjct: 268 IQELERSLSELKNQMAEPPSLAPPA-VTSVVEQLQDEAKHLRQEVEGLEGKLQSQVENNQ 326
Query: 122 ELSEV-KNVLEKLKNSER--------------RLLQDKEGLSNQLRVQTEVNRELKKL-- 164
LS + K ++L+ E RL + E L Q + E L+K
Sbjct: 327 ALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQ 386
Query: 165 LVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLAS-R 223
+ + L+ ERL +++ +L + E L + +L +Q ER+++ + K LA +
Sbjct: 387 RLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDKQLAEPQ 446
Query: 224 VMADELTNSRAA---LQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEEL 271
++L N + + L++Q ++ + + E + + + TQ L L
Sbjct: 447 CSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASHQNQQLETQLSLVAL 497
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 44.7 bits (104), Expect = 2e-04
Identities = 62/277 (22%), Positives = 111/277 (40%), Gaps = 32/277 (11%)
Query: 34 EVTSGVQSRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEVKAVRILVPKAAITHDIP 93
E S +Q R+ + Q E L+L + + + +E + A+ +P
Sbjct: 764 EEKSALQGRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLP 823
Query: 94 N----KNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSN 149
++ + L + G+ + + + +E LE+ + L ++ GL+
Sbjct: 824 TLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAREKEALAKEHAGLAV 883
Query: 150 QLRVQTEVNREL----------KKLLVASVGD------DLQYHFERLAREKNQLILENEA 193
QL R L K+ L S+ + L+ E+L E L+L E
Sbjct: 884 QLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAKET 943
Query: 194 LGRNTAQLSEQL----ERMSIQCDVWRSKFL-ASRVMADELTNSRAA----LQRQNRDAH 244
L A L +Q+ E+ S+ ++ K + A R L RAA LQR R+
Sbjct: 944 LTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQREKE 1003
Query: 245 GAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQ 281
A ++L +ER Q + ++ Q+ EELL L+ +E+
Sbjct: 1004 AAWRELEAERAQLQSQL---QREQEELLARLEAEKEE 1037
Score = 40.0 bits (92), Expect = 0.004
Identities = 54/280 (19%), Positives = 119/280 (42%), Gaps = 28/280 (10%)
Query: 7 ETKVTVTSSPIRGAGDGMETEEPPKSVEVTSGVQSRKHHSLQSPWKKAVPSESPGVLQLG 66
E ++ +RG G T PP+ G R+ S S+S + +
Sbjct: 474 ERTADASNGSLRGLS-GQRTPSPPRRSSPGRGRSPRRGPS-------PACSDSSTLALIH 525
Query: 67 KMLTEKAMEVKAVRILVPKA-----AITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
L ++ ++V+ +R + + + + ++ ++L +++G ++ ++
Sbjct: 526 SALHKRQLQVQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHE 585
Query: 122 ELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT----EVNRELKKLLVASVGDDLQYHF 177
+ + +++L+++ L ++K L++ L+V E+ +E +KL A ++L+
Sbjct: 586 D---AQREVQRLRSANELLSREKSNLAHSLQVAQQQAEELRQEREKLQAAQ--EELRRQR 640
Query: 178 ERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQ 237
+RL E+ + + + R + QLE++ + LA ++ SRA LQ
Sbjct: 641 DRLEEEQEDAVQDGARVRRELERSHRQLEQLE-----GKRSVLAKELVEVREALSRATLQ 695
Query: 238 RQNRDAHGA-IQDLLSEREQFRQEMIATQKLLEELLVSLQ 276
R A A + + L++ E R E+ + L SLQ
Sbjct: 696 RDMLQAEKAEVAEALTKAEAGRVELELSMTKLRAEEASLQ 735
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 43.9 bits (102), Expect = 3e-04
Identities = 59/219 (26%), Positives = 89/219 (40%), Gaps = 35/219 (15%)
Query: 88 ITHD-IPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDK-- 144
I H+ I ++K+ + K + + E E + E++N L L+ E LLQ K
Sbjct: 591 ILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEK-ENELLQKKIT 649
Query: 145 ---------EGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALG 195
E L + NR+LKK L + +L + E L +E +QL EN L
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSF--KNLTFQLESLEKENSQLDEENLELR 707
Query: 196 RNTAQLS--------EQLERMSIQCDVWRSK-----FLASRVMADELTNSRAALQRQNR- 241
RN L QLE ++ + + K AS + L S L +N+
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR 767
Query: 242 ------DAHGAIQDLLSEREQFRQEMIATQKLLEELLVS 274
+++ IQ L SE + E QK LEEL +S
Sbjct: 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS 806
Score = 33.1 bits (74), Expect = 0.46
Identities = 30/141 (21%), Positives = 56/141 (39%), Gaps = 16/141 (11%)
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGD--DLQY 175
E +EL +VK+ L +++ + L +K+ L QL+ N L+ ++A LQ
Sbjct: 1036 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1095
Query: 176 HFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAA 235
L + +L +EN L + L Q ++ IQ L N +
Sbjct: 1096 QNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ--------------QSSLENENES 1141
Query: 236 LQRQNRDAHGAIQDLLSEREQ 256
+ ++ D L+ + E+
Sbjct: 1142 VIKEREDLKSLYDSLIKDHEK 1162
Score = 29.3 bits (64), Expect = 6.6
Identities = 33/189 (17%), Positives = 82/189 (43%), Gaps = 22/189 (11%)
Query: 99 VKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEG------------ 146
+K+L + + + + + N +L ++ + LEK+ ++ RLL D++
Sbjct: 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESK 960
Query: 147 LSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLARE-----KNQLIL----ENEALGRN 197
L + L+ E+ E L A + + Y+ ++L +E KN L + E + ++
Sbjct: 961 LESTLKKSLEIKEEKIAALEARLEESTNYN-QQLRQELKTVKKNYEALKQRQDEERMVQS 1019
Query: 198 TAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQF 257
+ +S + + + + L + E+ + A LQ + + ++ L ++
Sbjct: 1020 SPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNL 1079
Query: 258 RQEMIATQK 266
+ +++A Q+
Sbjct: 1080 QAQILALQR 1088
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 43.9 bits (102), Expect = 3e-04
Identities = 59/219 (26%), Positives = 89/219 (40%), Gaps = 35/219 (15%)
Query: 88 ITHD-IPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDK-- 144
I H+ I ++K+ + K + + E E + E++N L L+ E LLQ K
Sbjct: 591 ILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEK-ENELLQKKIT 649
Query: 145 ---------EGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALG 195
E L + NR+LKK L + +L + E L +E +QL EN L
Sbjct: 650 NLKITCEKIEALEQENSELERENRKLKKTLDSF--KNLTFQLESLEKENSQLDEENLELR 707
Query: 196 RNTAQLS--------EQLERMSIQCDVWRSK-----FLASRVMADELTNSRAALQRQNR- 241
RN L QLE ++ + + K AS + L S L +N+
Sbjct: 708 RNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQR 767
Query: 242 ------DAHGAIQDLLSEREQFRQEMIATQKLLEELLVS 274
+++ IQ L SE + E QK LEEL +S
Sbjct: 768 LQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKIS 806
Score = 33.1 bits (74), Expect = 0.46
Identities = 30/141 (21%), Positives = 56/141 (39%), Gaps = 16/141 (11%)
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGD--DLQY 175
E +EL +VK+ L +++ + L +K+ L QL+ N L+ ++A LQ
Sbjct: 1035 ETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQE 1094
Query: 176 HFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAA 235
L + +L +EN L + L Q ++ IQ L N +
Sbjct: 1095 QNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ--------------QSSLENENES 1140
Query: 236 LQRQNRDAHGAIQDLLSEREQ 256
+ ++ D L+ + E+
Sbjct: 1141 VIKEREDLKSLYDSLIKDHEK 1161
Score = 29.6 bits (65), Expect = 5.0
Identities = 33/188 (17%), Positives = 82/188 (43%), Gaps = 21/188 (11%)
Query: 99 VKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEG-----------L 147
+K+L + + + + + N +L ++ + LEK+ ++ RLL D++ L
Sbjct: 901 IKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDRYKLLESKL 960
Query: 148 SNQLRVQTEVNRELKKLLVASVGDDLQYHFERLARE-----KNQLIL----ENEALGRNT 198
+ L+ E+ E L A + + Y+ ++L +E KN L + E + +++
Sbjct: 961 ESTLKKSLEIKEEKIAALEARLEESTNYN-QQLRQELKTVKKNYEALKQRQDEERMVQSS 1019
Query: 199 AQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFR 258
+S + + + + L + E+ + A LQ + + ++ L ++ +
Sbjct: 1020 PPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQ 1079
Query: 259 QEMIATQK 266
+++A Q+
Sbjct: 1080 AQILALQR 1087
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 43.5 bits (101), Expect = 3e-04
Identities = 40/185 (21%), Positives = 86/185 (46%), Gaps = 32/185 (17%)
Query: 116 VIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQL-----------RVQTEVNRELKKL 164
V + K++ + LE + +R+L +D EGLS + + +T + +EL L
Sbjct: 1366 VADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDL 1425
Query: 165 LVASVGDDLQY------HFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSK 218
LV DL + + E+ ++ +QL+ E + + +A+ +E+ +R + +K
Sbjct: 1426 LV-----DLDHQRQSACNLEKKQKKFDQLLAEEKTI---SAKYAEERDRAEAEAREKETK 1477
Query: 219 FLASRVMADELTNSRAALQRQNRDAHGAIQDLLSERE-------QFRQEMIATQKLLEEL 271
L+ +E +A L+R N+ ++DL+S ++ + + A ++ +EE+
Sbjct: 1478 ALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEM 1537
Query: 272 LVSLQ 276
L+
Sbjct: 1538 KTQLE 1542
Score = 40.8 bits (94), Expect = 0.002
Identities = 54/258 (20%), Positives = 103/258 (39%), Gaps = 55/258 (21%)
Query: 67 KMLTEKAMEVKAVRILVPKAAITHDIPNKN-----TKVKSL---GHHKGEFLGQSEGVIE 118
K ++ ++ A+++L A + N TKVK L + E + + E +++
Sbjct: 797 KAFAKRQQQLTAMKVLQRNCAAYLKLRNWQWWRLFTKVKPLLQVSRQEEEMMAKEEELVK 856
Query: 119 PNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNREL---------KKLLVASV 169
++ +N L +++ + +L+ +K L QL+ +TE+ E KK + +
Sbjct: 857 VREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEI 916
Query: 170 GDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLE-----RMSIQ------------- 211
DL+ E L E + + +N +L EQLE R +Q
Sbjct: 917 CHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKL 976
Query: 212 -----------CDVWRSKFLASRVMADELTN---------SRAALQRQNRDAHGAIQDLL 251
C + + K L +A+ TN S A L+ ++ +++ L
Sbjct: 977 EEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERL 1036
Query: 252 SEREQFRQEMIATQKLLE 269
E+ RQE+ T++ LE
Sbjct: 1037 RREEKQRQELEKTRRKLE 1054
Score = 40.0 bits (92), Expect = 0.004
Identities = 34/133 (25%), Positives = 65/133 (48%), Gaps = 5/133 (3%)
Query: 123 LSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLL--VASVGDDLQYHFE-- 178
L++ K +KLK+ E ++Q +E L+ R + + +E +L +A+ E
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 179 -RLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQ 237
RL QL E E NT ++++L++ ++Q D + R A + N+R L+
Sbjct: 1725 RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLE 1784
Query: 238 RQNRDAHGAIQDL 250
RQN++ +Q++
Sbjct: 1785 RQNKELKVKLQEM 1797
Score = 28.9 bits (63), Expect = 8.6
Identities = 28/142 (19%), Positives = 66/142 (46%), Gaps = 4/142 (2%)
Query: 120 NKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFER 179
N +L+ ++ +K +N+ ++L + + L +L+ E+ +K AS+ L+ +
Sbjct: 1763 NTDLNLERSHAQKNENARQQLERQNKELKVKLQ---EMEGTVKSKYKASI-TALEAKIAQ 1818
Query: 180 LAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQ 239
L + + E +A + + ++L+ + +Q D R + AD+ + L+RQ
Sbjct: 1819 LEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQ 1878
Query: 240 NRDAHGAIQDLLSEREQFRQEM 261
+A Q + R + ++E+
Sbjct: 1879 LEEAEEEAQRANASRRKLQREL 1900
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 43.5 bits (101), Expect = 3e-04
Identities = 57/249 (22%), Positives = 98/249 (39%), Gaps = 14/249 (5%)
Query: 31 KSVEVTSGVQSRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEVKAVRILVPKAAITH 90
KSVE Q + LQ + + L+ K + EK E++ +R+L+ + T
Sbjct: 1126 KSVEDRFDQQKNDYDQLQKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEG-TR 1184
Query: 91 DIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQ 150
+N K H+ E NK +E+ +K + D + L NQ
Sbjct: 1185 KREYENELAKVRNHYNEEMSNLR------NKYETEINITKTTIKEISMQKEDDSKNLRNQ 1238
Query: 151 LRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSI 210
L + NR+LK +V LQ +R E+N L+ +A G Q + LE
Sbjct: 1239 LDRLSRENRDLKDEIVRLNDSILQATEQRRRAEEN--ALQQKACGSEIMQKKQHLEIELK 1296
Query: 211 QCDVWRSKFLASRVMADELTNSRAALQRQNRDAH---GAIQDLLSEREQFRQEMIATQKL 267
Q RS+ A L + +Q +N++ Q+ R ++ E+ +
Sbjct: 1297 QVMQQRSEDNARH--KQSLEEAAKTIQDKNKEIERLKAEFQEEAKRRWEYENELSKVRNN 1354
Query: 268 LEELLVSLQ 276
+E ++SL+
Sbjct: 1355 YDEEIISLK 1363
Score = 36.6 bits (83), Expect = 0.041
Identities = 47/182 (25%), Positives = 72/182 (39%), Gaps = 38/182 (20%)
Query: 134 KNSERRLLQDKEGLSNQLRVQTEVNRELKKLL--VASVGDDL-------------QYHFE 178
K SE L Q ++ L LR + EL++L V ++ L HF+
Sbjct: 1627 KRSEDDLRQQRDVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRNEHFQ 1686
Query: 179 RLAREKNQLILEN-----------EALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMAD 227
+ +K++ + E+ E L + L E+L + ++ D R R AD
Sbjct: 1687 KAIEDKSRSLNESKIEIERLQSLTENLTKEHLMLEEELRNLRLEYDDLRR----GRSEAD 1742
Query: 228 ELTNS-----RAALQRQNR---DAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGR 279
N+ R+ LQ N + G I DL ERE RQE+ QK E +Q +
Sbjct: 1743 SDKNATILELRSQLQISNNRTLELQGLINDLQRERENLRQEIEKFQKQALEASNRIQESK 1802
Query: 280 EQ 281
Q
Sbjct: 1803 NQ 1804
Score = 31.2 bits (69), Expect = 1.7
Identities = 42/193 (21%), Positives = 77/193 (39%), Gaps = 36/193 (18%)
Query: 109 FLGQSEGVIEPNKELSE----VKNVLEKLKNSERRLLQD--------------KEGLSNQ 150
+ Q + + N+ LSE +KN L + + RR+ +D K+ L +
Sbjct: 1391 YRAQIDNLTRENRSLSEEIKRLKNTLTQTTENLRRVEEDIQQQKATGSEVSQRKQQLEVE 1450
Query: 151 LRVQTEVNRELKKLLVASVGD------DLQYHFERLAREKNQLILENEALGRNTAQLSEQ 204
LR T++ E S+ D D ERL + +++ E R + E
Sbjct: 1451 LRQVTQMRTEESVRYKQSLDDAAKTIQDKNKEIERLKQ-----LIDKETNDRKCLE-DEN 1504
Query: 205 LERMSIQCDVWRSKFLAS------RVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFR 258
+Q D+ ++ A+ +V ELT R +R +++ QD+ + +
Sbjct: 1505 ARLQRVQYDLQKANSSATETINKLKVQEQELTRLRIDYERVSQERTVKDQDITRFQNSLK 1564
Query: 259 QEMIATQKLLEEL 271
+ + QK+ EEL
Sbjct: 1565 ELQLQKQKVEEEL 1577
Score = 30.4 bits (67), Expect = 3.0
Identities = 24/136 (17%), Positives = 62/136 (45%), Gaps = 1/136 (0%)
Query: 125 EVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVA-SVGDDLQYHFERLARE 183
E +N+ ++++ +++ L+ + T+V +E + LLV V + + +RL E
Sbjct: 1776 ERENLRQEIEKFQKQALEASNRIQESKNQCTQVVQERESLLVKIKVLEQDKARLQRLEDE 1835
Query: 184 KNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDA 243
N+ EA R +L + +++ + W++++ ++ + R +R+
Sbjct: 1836 LNRAKSTLEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSL 1895
Query: 244 HGAIQDLLSEREQFRQ 259
I+ L +E ++ +
Sbjct: 1896 RSEIERLQAEIKRIEE 1911
>gi|56550047 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 2 [Homo sapiens]
Length = 1403
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/217 (21%), Positives = 95/217 (43%), Gaps = 11/217 (5%)
Query: 62 VLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
+L + + TEK +E++ ++L+ +++ D+ T H+ E + ++E K
Sbjct: 755 LLDVTQKYTEKKLEME--KLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKK 812
Query: 122 ELSEVKNVL----EKLKNSERRLLQDKEGLSNQ---LRVQTEVNRELKKLLVASVGD--D 172
+LSE+K EK+ K+ +SNQ ++ EV L L + + D
Sbjct: 813 QLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 872
Query: 173 LQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNS 232
++ FE + +E ++ +NE L RN Q++ I +K + ++ +S
Sbjct: 873 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 932
Query: 233 RAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLE 269
A + R I L +E + ++E+ Q+ ++
Sbjct: 933 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIK 969
Score = 34.3 bits (77), Expect = 0.20
Identities = 48/243 (19%), Positives = 102/243 (41%), Gaps = 37/243 (15%)
Query: 66 GKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSE 125
G+ +TE + K + + + N + + + + K + L + E E K LSE
Sbjct: 593 GRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMER--EHEKSLSE 650
Query: 126 VKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKN 185
++ + +L+N + +L Q V+ E + ++K L G+ L ++
Sbjct: 651 IRQLKRELENVKAKLAQ---------HVKPEEHEQVKSRLEQKSGE--------LGKKIT 693
Query: 186 QLILENEALGRNTAQ-------LSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQR 238
+L L+N+ L + + L EQ ++I+ ++ ++ +V D + A +
Sbjct: 694 ELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIE---MKNHYVPLKVSEDMKKSHDAIIDD 750
Query: 239 QNRDAHGAIQDLLSEREQFRQEMIATQK-LLEELLVSLQWGREQTYSPSVQPHSTAELAL 297
NR LL +++ ++ + +K LLE +S R +T + H +AL
Sbjct: 751 LNR-------KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIAL 803
Query: 298 TNH 300
++
Sbjct: 804 KSN 806
Score = 29.3 bits (64), Expect = 6.6
Identities = 50/246 (20%), Positives = 88/246 (35%), Gaps = 58/246 (23%)
Query: 122 ELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT------EVNRELKKLLVASVGDDLQY 175
E ++K L K++ +R LL GL QL + E RE K L+A+ +
Sbjct: 289 ENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEE 348
Query: 176 HFERLAREKNQL-ILENEALGRNTAQLSEQLERMSI----------QC------------ 212
+ KN+ E++ LG + S + E M + QC
Sbjct: 349 SLRTIEALKNRFKYFESDHLGSGS-HFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR 407
Query: 213 -------------------DVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSE 253
++ + + A R + R LQ + + L E
Sbjct: 408 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE 467
Query: 254 REQFRQEMIATQKLLEELLVSLQWG---------REQTYSPSVQPHSTAELALTNHKLAK 304
E+ +++ K LE+ L +Q + QT+ +++ H T+E A NH+L +
Sbjct: 468 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE 527
Query: 305 AVNSHL 310
+ L
Sbjct: 528 ELKDQL 533
>gi|59850762 uveal autoantigen with coiled-coil domains and ankyrin
repeats isoform 1 [Homo sapiens]
Length = 1416
Score = 43.5 bits (101), Expect = 3e-04
Identities = 46/217 (21%), Positives = 95/217 (43%), Gaps = 11/217 (5%)
Query: 62 VLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNK 121
+L + + TEK +E++ ++L+ +++ D+ T H+ E + ++E K
Sbjct: 768 LLDVTQKYTEKKLEME--KLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKK 825
Query: 122 ELSEVKNVL----EKLKNSERRLLQDKEGLSNQ---LRVQTEVNRELKKLLVASVGD--D 172
+LSE+K EK+ K+ +SNQ ++ EV L L + + D
Sbjct: 826 QLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 885
Query: 173 LQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNS 232
++ FE + +E ++ +NE L RN Q++ I +K + ++ +S
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 233 RAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLE 269
A + R I L +E + ++E+ Q+ ++
Sbjct: 946 NAEILANYRKGQEEIVTLHAEIKAQKKELDTIQECIK 982
Score = 34.3 bits (77), Expect = 0.20
Identities = 48/243 (19%), Positives = 102/243 (41%), Gaps = 37/243 (15%)
Query: 66 GKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSE 125
G+ +TE + K + + + N + + + + K + L + E E K LSE
Sbjct: 606 GRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMER--EHEKSLSE 663
Query: 126 VKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKN 185
++ + +L+N + +L Q V+ E + ++K L G+ L ++
Sbjct: 664 IRQLKRELENVKAKLAQ---------HVKPEEHEQVKSRLEQKSGE--------LGKKIT 706
Query: 186 QLILENEALGRNTAQ-------LSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQR 238
+L L+N+ L + + L EQ ++I+ ++ ++ +V D + A +
Sbjct: 707 ELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIE---MKNHYVPLKVSEDMKKSHDAIIDD 763
Query: 239 QNRDAHGAIQDLLSEREQFRQEMIATQK-LLEELLVSLQWGREQTYSPSVQPHSTAELAL 297
NR LL +++ ++ + +K LLE +S R +T + H +AL
Sbjct: 764 LNR-------KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIAL 816
Query: 298 TNH 300
++
Sbjct: 817 KSN 819
Score = 29.3 bits (64), Expect = 6.6
Identities = 50/246 (20%), Positives = 88/246 (35%), Gaps = 58/246 (23%)
Query: 122 ELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT------EVNRELKKLLVASVGDDLQY 175
E ++K L K++ +R LL GL QL + E RE K L+A+ +
Sbjct: 302 ENEDLKERLRKIQQEQRILLDKVNGLQLQLNEEVMVADDLESEREKLKSLLAAKEKQHEE 361
Query: 176 HFERLAREKNQL-ILENEALGRNTAQLSEQLERMSI----------QC------------ 212
+ KN+ E++ LG + S + E M + QC
Sbjct: 362 SLRTIEALKNRFKYFESDHLGSGS-HFSNRKEDMLLKQGQMYMADSQCTSPGIPAHMQSR 420
Query: 213 -------------------DVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSE 253
++ + + A R + R LQ + + L E
Sbjct: 421 SMLRPLELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALE 480
Query: 254 REQFRQEMIATQKLLEELLVSLQWG---------REQTYSPSVQPHSTAELALTNHKLAK 304
E+ +++ K LE+ L +Q + QT+ +++ H T+E A NH+L +
Sbjct: 481 CERVKEDSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTE 540
Query: 305 AVNSHL 310
+ L
Sbjct: 541 ELKDQL 546
>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
Length = 3907
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/191 (20%), Positives = 88/191 (46%), Gaps = 21/191 (10%)
Query: 108 EFLGQ-SEGVIEPNKELSEVKNVLEKLKNSERRLLQDKE---GLSNQLRVQTEVNRELKK 163
+ LG+ E +++ N+E+ +K L K ER+ ++ + G +L+ + + + +
Sbjct: 357 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFET 416
Query: 164 LLVASVGDDLQYHFERLAREKNQLI------LENEALGRNTAQLSEQLERMSIQCDVWRS 217
+V + + Q E+L E +++ ++ E + ++ AQ+ E R + +
Sbjct: 417 DIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALR 476
Query: 218 KFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEM-------IATQKLLEE 270
+ V D++ A+ N +QD S++E+ ++E+ A Q+ LE+
Sbjct: 477 SYSNITVNEDQIKLMNVAINELNIK----LQDTNSQKEKLKEELGLILEEKCALQRQLED 532
Query: 271 LLVSLQWGREQ 281
L+ L + REQ
Sbjct: 533 LVEELSFSREQ 543
Score = 32.7 bits (73), Expect = 0.60
Identities = 31/163 (19%), Positives = 71/163 (43%), Gaps = 17/163 (10%)
Query: 121 KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL 180
+ELS++K LE L+D G+ + ++ N +K+ + +Q+ + L
Sbjct: 635 EELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKI------ETMQFEKDNL 688
Query: 181 AREKNQLILE--------NEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVM---ADEL 229
++NQLILE + + +++ Q+ + + ++ R + + EL
Sbjct: 689 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 748
Query: 230 TNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELL 272
L++Q ++ +Q+ ++ E + +K LE++L
Sbjct: 749 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791
Score = 32.0 bits (71), Expect = 1.0
Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%)
Query: 123 LSEVKNVLEKLKNSERRLLQDK-EGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLA 181
L +VK+ LE KN + + K + L+ +L +Q +N K+ + +D + E L
Sbjct: 871 LLKVKDDLEDSKNKQELEYKSKLKALNEELHLQ-RINPTTVKMKSSVFDEDKTFVAETLE 929
Query: 182 REKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNR 241
E + ++T +L E+LE R K S+ ++D L Q +
Sbjct: 930 M--------GEVVEKDTTELMEKLEVTK------REKLELSQRLSD--------LSEQLK 967
Query: 242 DAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGR-EQTYSPSVQPHSTAELALT-N 299
HG I L E + +QE EL + + R E S Q S + +T
Sbjct: 968 QKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMT 1027
Query: 300 HKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILD--PVTCKESS 353
+ A+ S + + G ++ + V F + + ++ ILD P KESS
Sbjct: 1028 SRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESS 1083
Score = 30.4 bits (67), Expect = 3.0
Identities = 33/158 (20%), Positives = 72/158 (45%), Gaps = 13/158 (8%)
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNREL--KKLLVASVGDDL-- 173
+P++EL E ++ + ++L+ + LS+ TE+ +L +K++VA + +L
Sbjct: 3116 KPSQELLEYN-----IQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQ 3170
Query: 174 -QYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNS 232
+ E + +++ + E EA ++ ++ + + + D S+ SR + L
Sbjct: 3171 TKLELETTLKAQHKHLKELEAF---RLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKE 3227
Query: 233 RAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEE 270
+A L R ++DL E +Q + LLE+
Sbjct: 3228 KAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQ 3265
Score = 29.3 bits (64), Expect = 6.6
Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 108 EFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVA 167
E L + V N+E++ +KNVL++ +L Q+ L + RE + + +
Sbjct: 2394 EKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRE--------RESVEKIQS 2445
Query: 168 SVGDDLQYHFERLAREKNQL--ILENEAL----GRNTAQLSEQLERMSIQCDVWRSKFLA 221
+ + + L+++K +L +L +AL + + E+ + SI R L
Sbjct: 2446 IPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLE 2505
Query: 222 SRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQ 281
S V A +L ++ Q ++ G + + +++ + I +K+ L+ +Q Q
Sbjct: 2506 STVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQ 2565
Query: 282 TYSPSVQPHST 292
Y+ Q + T
Sbjct: 2566 EYAKFCQDNQT 2576
>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
Length = 3899
Score = 43.1 bits (100), Expect = 4e-04
Identities = 40/191 (20%), Positives = 88/191 (46%), Gaps = 21/191 (10%)
Query: 108 EFLGQ-SEGVIEPNKELSEVKNVLEKLKNSERRLLQDKE---GLSNQLRVQTEVNRELKK 163
+ LG+ E +++ N+E+ +K L K ER+ ++ + G +L+ + + + +
Sbjct: 357 KLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFET 416
Query: 164 LLVASVGDDLQYHFERLAREKNQLI------LENEALGRNTAQLSEQLERMSIQCDVWRS 217
+V + + Q E+L E +++ ++ E + ++ AQ+ E R + +
Sbjct: 417 DIVQRMEQETQRKLEQLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALR 476
Query: 218 KFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEM-------IATQKLLEE 270
+ V D++ A+ N +QD S++E+ ++E+ A Q+ LE+
Sbjct: 477 SYSNITVNEDQIKLMNVAINELNIK----LQDTNSQKEKLKEELGLILEEKCALQRQLED 532
Query: 271 LLVSLQWGREQ 281
L+ L + REQ
Sbjct: 533 LVEELSFSREQ 543
Score = 32.7 bits (73), Expect = 0.60
Identities = 31/163 (19%), Positives = 71/163 (43%), Gaps = 17/163 (10%)
Query: 121 KELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERL 180
+ELS++K LE L+D G+ + ++ N +K+ + +Q+ + L
Sbjct: 635 EELSKLKEDLEIEHRINIEKLKDNLGIHYKQQIDGLQNEMSQKI------ETMQFEKDNL 688
Query: 181 AREKNQLILE--------NEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVM---ADEL 229
++NQLILE + + +++ Q+ + + ++ R + + EL
Sbjct: 689 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 748
Query: 230 TNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELL 272
L++Q ++ +Q+ ++ E + +K LE++L
Sbjct: 749 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDML 791
Score = 32.0 bits (71), Expect = 1.0
Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 28/236 (11%)
Query: 123 LSEVKNVLEKLKNSERRLLQDK-EGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLA 181
L +VK+ LE KN + + K + L+ +L +Q +N K+ + +D + E L
Sbjct: 871 LLKVKDDLEDSKNKQELEYKSKLKALNEELHLQ-RINPTTVKMKSSVFDEDKTFVAETLE 929
Query: 182 REKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNR 241
E + ++T +L E+LE R K S+ ++D L Q +
Sbjct: 930 M--------GEVVEKDTTELMEKLEVTK------REKLELSQRLSD--------LSEQLK 967
Query: 242 DAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGR-EQTYSPSVQPHSTAELALT-N 299
HG I L E + +QE EL + + R E S Q S + +T
Sbjct: 968 QKHGEISFLNEEVKSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDGVVTMT 1027
Query: 300 HKLAKAVNSHLLGNVGINNQKKIPSTVEFCSTPAEKMAETVLRILD--PVTCKESS 353
+ A+ S + + G ++ + V F + + ++ ILD P KESS
Sbjct: 1028 SRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHLPSVTKESS 1083
Score = 30.4 bits (67), Expect = 3.0
Identities = 33/158 (20%), Positives = 72/158 (45%), Gaps = 13/158 (8%)
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNREL--KKLLVASVGDDL-- 173
+P++EL E ++ + ++L+ + LS+ TE+ +L +K++VA + +L
Sbjct: 3108 KPSQELLEYN-----IQQKQSQMLEMQVELSSMKDRATELQEQLSSEKMVVAELKSELAQ 3162
Query: 174 -QYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNS 232
+ E + +++ + E EA ++ ++ + + + D S+ SR + L
Sbjct: 3163 TKLELETTLKAQHKHLKELEAF---RLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKE 3219
Query: 233 RAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEE 270
+A L R ++DL E +Q + LLE+
Sbjct: 3220 KAKLGRSEERDKEELEDLKFSLESQKQRNLQLNLLLEQ 3257
Score = 29.3 bits (64), Expect = 6.6
Identities = 39/191 (20%), Positives = 82/191 (42%), Gaps = 14/191 (7%)
Query: 108 EFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVA 167
E L + V N+E++ +KNVL++ +L Q+ L + RE + + +
Sbjct: 2386 EKLALEQQVETANEEMTFMKNVLKETNFKMNQLTQELFSLKRE--------RESVEKIQS 2437
Query: 168 SVGDDLQYHFERLAREKNQL--ILENEAL----GRNTAQLSEQLERMSIQCDVWRSKFLA 221
+ + + L+++K +L +L +AL + + E+ + SI R L
Sbjct: 2438 IPENSVNVAIDHLSKDKPELEVVLTEDALKSLENQTYFKSFEENGKGSIINLETRLLQLE 2497
Query: 222 SRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQ 281
S V A +L ++ Q ++ G + + +++ + I +K+ L+ +Q Q
Sbjct: 2498 STVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQLEAVQ 2557
Query: 282 TYSPSVQPHST 292
Y+ Q + T
Sbjct: 2558 EYAKFCQDNQT 2568
>gi|169208458 PREDICTED: similar to golgi autoantigen, golgin
subfamily a-like [Homo sapiens]
Length = 432
Score = 42.4 bits (98), Expect = 8e-04
Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Query: 99 VKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVN 158
V+ LG + Q+ + P K +E+L++ L ++ E + QL+ + E N
Sbjct: 130 VQKLGRSLFKLKNQTAEPLAPQPPAGPSK--VEQLQDETNHLRKELESVGRQLQAEVE-N 186
Query: 159 RELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSK 218
++ LL + L+ ERL ++ +L + E L +L EQ ER+ Q + +
Sbjct: 187 NQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQE 246
Query: 219 FLASRVMADELTNSRAALQRQNRDAH-----GAIQDLLSE---REQ----FRQEMIATQK 266
L V ++L + Q R +++LL + R+Q ++QE + +
Sbjct: 247 RLLEEV--EKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELE 304
Query: 267 LLEELLVSLQWGREQTYSPSVQPHSTAE 294
L EL L+ G E Y +P S E
Sbjct: 305 RLRELERMLELGWEALYEQRAEPRSGFE 332
>gi|154937324 hypothetical protein LOC440295 [Homo sapiens]
Length = 432
Score = 42.4 bits (98), Expect = 8e-04
Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Query: 99 VKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVN 158
V+ LG + Q+ + P K +E+L++ L ++ E + QL+ + E N
Sbjct: 130 VQKLGRSLFKLKNQTAEPLAPQPPAGPSK--VEQLQDETNHLRKELESVGRQLQAEVE-N 186
Query: 159 RELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSK 218
++ LL + L+ ERL ++ +L + E L +L EQ ER+ Q + +
Sbjct: 187 NQMLSLLNRRQEERLREQEERLREQEERLCEQEERLCEQEERLREQEERLCEQEKLPGQE 246
Query: 219 FLASRVMADELTNSRAALQRQNRDAH-----GAIQDLLSE---REQ----FRQEMIATQK 266
L V ++L + Q R +++LL + R+Q ++QE + +
Sbjct: 247 RLLEEV--EKLLKQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELE 304
Query: 267 LLEELLVSLQWGREQTYSPSVQPHSTAE 294
L EL L+ G E Y +P S E
Sbjct: 305 RLRELERMLELGWEALYEQRAEPRSGFE 332
>gi|94721321 coiled-coil domain containing 11 [Homo sapiens]
Length = 514
Score = 42.0 bits (97), Expect = 0.001
Identities = 45/188 (23%), Positives = 88/188 (46%), Gaps = 19/188 (10%)
Query: 98 KVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEV 157
+V+ L H+ + + + I N+ELS K V E++ + L +++ L+ + R E
Sbjct: 165 RVELLSIHQKKVCEERKAQIAFNEELSRQKLVEEQMFSK----LWEEDRLAKEKREAQEA 220
Query: 158 NRELKKLLVASVGDDLQYHFERLAREKNQLILENEA--LGRNTAQLSEQLERMSIQCDVW 215
R+ + + +G + Q + R+ QL+ E EA + N AQ+ + E+ ++
Sbjct: 221 RRQKELMENTRLGLNAQITSIKAQRQATQLLKEEEARLVESNNAQIKHENEQDMLKKQ-- 278
Query: 216 RSKFLASRVMADELTNSRAALQRQNRDAHG--------AIQDLLSE---REQFRQEMIAT 264
++K ++ L +Q++ RD A+QDL E ++Q R++MI
Sbjct: 279 KAKQETRTILQKALQERIEHIQQEYRDEQDLNMKLVQRALQDLQEEADKKKQKREDMIRE 338
Query: 265 QKLLEELL 272
QK+ + L
Sbjct: 339 QKIYHKYL 346
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 41.6 bits (96), Expect = 0.001
Identities = 47/183 (25%), Positives = 81/183 (44%), Gaps = 21/183 (11%)
Query: 112 QSEGVIEPNKELS--------EVKNVLEKLKNSERRLLQDKEGLSNQ---LRVQTEVNRE 160
Q + +E N+ LS ++ E+L+ E RL + +E L Q LR Q E RE
Sbjct: 179 QLQAEVENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLRE 238
Query: 161 LKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFL 220
++ L + L+ H ERL ++ +L + E L +L EQ ER+ Q + R +
Sbjct: 239 QEERLCEQE-ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQ-- 295
Query: 221 ASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQF--RQEMIATQKLLEELLVSLQWG 278
+ L L+ Q + L + E+ ++++ ++LLEE+ L+
Sbjct: 296 -----EERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQE 350
Query: 279 REQ 281
R Q
Sbjct: 351 RRQ 353
Score = 39.7 bits (91), Expect = 0.005
Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 21/198 (10%)
Query: 112 QSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQ---LRVQTEVNRELKKLLVAS 168
Q E + E + L E + E+L+ E RL + +E L Q LR Q E E ++ L
Sbjct: 232 QEERLREQEERLCEQE---ERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQ 288
Query: 169 VGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADE 228
+ L+ ERL ++ +L + E L +L EQ ER+ Q + + L V ++
Sbjct: 289 E-ERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEV--EK 345
Query: 229 LTNSRAALQRQNR--DAHGAIQDL--LSEREQFRQ--------EMIATQKLLEELLVSLQ 276
L + Q R + ++++ L E+E+ RQ E + + L EL L+
Sbjct: 346 LLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLE 405
Query: 277 WGREQTYSPSVQPHSTAE 294
G E Y +P S E
Sbjct: 406 LGWEALYEQRAEPRSGFE 423
>gi|239745259 PREDICTED: hypothetical protein isoform 2 [Homo
sapiens]
Length = 432
Score = 41.6 bits (96), Expect = 0.001
Identities = 50/208 (24%), Positives = 89/208 (42%), Gaps = 17/208 (8%)
Query: 99 VKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVN 158
V+ LG + Q+ + P K +E+L++ L ++ E + QL+ + E N
Sbjct: 130 VQKLGRSLFKLKNQTAEPLAPEPPAGPSK--VEQLQDETNHLRKELESVGRQLQAEVE-N 186
Query: 159 RELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSK 218
++ LL + L+ ERL ++ +L + E L +L EQ ER+ Q + +
Sbjct: 187 NQMLSLLNRRQEERLREQEERLREQEERLHEQEERLCEQEERLCEQEERLCEQEKLPGQE 246
Query: 219 FLASRVMADELTNSRAALQRQNRDAH-----GAIQDLLSE---REQ----FRQEMIATQK 266
L V ++L + Q R +++LL + R+Q ++QE + +
Sbjct: 247 RLLEEV--EKLLEQERRQEEQERLLERERLLDEVEELLEQERLRQQDERLWQQETLRELE 304
Query: 267 LLEELLVSLQWGREQTYSPSVQPHSTAE 294
L EL L+ G E Y +P S E
Sbjct: 305 RLRELERMLELGWEALYEQRAEPRSGFE 332
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 9/117 (7%)
Query: 100 KSLGHHKGEFLGQSEGVI-EPNKELSEVKNVLEKLKNSERRL-----LQDKEGLSNQLRV 153
+ LGH +G G+S I E K + +K V+EK++ +L + E ++N +
Sbjct: 2112 RKLGHVRGS--GRSGKTIPELEKTIGLMKKVVEKVQRENEQLKKASGILTSEKMANIEQE 2169
Query: 154 QTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSI 210
++ EL+KL A +G L H+E + ++I ENE L + + ++ E++ I
Sbjct: 2170 NEKLKAELEKLK-AHLGHQLSMHYESKTKGTEKIIAENERLRKELKKETDAAEKLRI 2225
Score = 30.4 bits (67), Expect = 3.0
Identities = 33/167 (19%), Positives = 71/167 (42%), Gaps = 8/167 (4%)
Query: 118 EPNKELSEVKNVLEKLKNSERR-----LLQDKEGLSNQLRVQTEVNRELKKLLVASVGDD 172
+ KE +K+ L+ K + R + E L +QL ++ + + L + L+ +
Sbjct: 1696 QSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLALKEKQQKALSRALLELRAEM 1755
Query: 173 LQYHFERL---AREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADEL 229
ER+ +K + + + R+T +L Q+E ++ + S+ + L
Sbjct: 1756 TAAAEERIISATSQKEAHLNVQQIVDRHTRELKTQVEDLNENLLKLKEALKTSKNRENSL 1815
Query: 230 TNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQ 276
T++ L + + A +L E+E+ QE ++ ++ L LQ
Sbjct: 1816 TDNLNDLNNELQKKQKAYNKILREKEEIDQENDELKRQIKRLTSGLQ 1862
>gi|214010165 rab11-family interacting protein 3 isoform 2 [Homo
sapiens]
Length = 460
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/136 (29%), Positives = 57/136 (41%), Gaps = 22/136 (16%)
Query: 123 LSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAR 182
L E + E L ER + E L +L+ E N EL+ S L+ + ERL
Sbjct: 224 LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELR-----SCTPCLKANIERLEE 278
Query: 183 EKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRD 242
EK +L+ E E+L T +LSE+ E R M D L++ R QR
Sbjct: 279 EKQKLLDEIESL---TLRLSEEQEN--------------KRRMGDRLSHERHQFQRDKEA 321
Query: 243 AHGAIQDLLSEREQFR 258
I+DL + E +
Sbjct: 322 TQELIEDLRKQLEHLQ 337
Score = 39.7 bits (91), Expect = 0.005
Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 19/169 (11%)
Query: 116 VIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT--------EVNRELKKLLVA 167
V+E K+ + +L+ +L+ L QL+ Q E R K+LL
Sbjct: 177 VLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELL-C 235
Query: 168 SVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMAD 227
+ + E L QL EN L T L +ER+ + + + D
Sbjct: 236 KMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEE----------KQKLLD 285
Query: 228 ELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQ 276
E+ + L + + L ER QF+++ ATQ+L+E+L L+
Sbjct: 286 EIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLE 334
Score = 31.2 bits (69), Expect = 1.7
Identities = 45/227 (19%), Positives = 97/227 (42%), Gaps = 27/227 (11%)
Query: 65 LGKMLTEKAMEVKAVRILVPK-----AAITHDIPNKNTKVKSLGHHKGEFLGQSEGV-IE 118
L KM EK++E++ ++ + + + + P ++ L K + L + E + +
Sbjct: 234 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 293
Query: 119 PNKELSEVKNVLEKLKNSERRLLQDKEG---LSNQLRVQTE------VNRELKKLLVASV 169
++E + + ++L + + +DKE L LR Q E + E ++ +S+
Sbjct: 294 LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSM 353
Query: 170 GDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADEL 229
G +YH E Q + + RN + +E+L I + +K L S ++ L
Sbjct: 354 GLQ-EYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESL 412
Query: 230 TNSRAALQRQNRDAHGAIQDLLSEREQFRQEM-IATQKLLEELLVSL 275
+++ R D L E Q ++E+ Q ++ ++V++
Sbjct: 413 AAEISSVSR----------DELMEAIQKQEEINFRLQDYIDRIIVAI 449
>gi|7662234 rab11-family interacting protein 3 isoform 1 [Homo
sapiens]
Length = 756
Score = 40.8 bits (94), Expect = 0.002
Identities = 40/136 (29%), Positives = 57/136 (41%), Gaps = 22/136 (16%)
Query: 123 LSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAR 182
L E + E L ER + E L +L+ E N EL+ S L+ + ERL
Sbjct: 520 LEETRRQKELLCKMEREKSIEIENLQTRLQQLDEENSELR-----SCTPCLKANIERLEE 574
Query: 183 EKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRD 242
EK +L+ E E+L T +LSE+ E R M D L++ R QR
Sbjct: 575 EKQKLLDEIESL---TLRLSEEQEN--------------KRRMGDRLSHERHQFQRDKEA 617
Query: 243 AHGAIQDLLSEREQFR 258
I+DL + E +
Sbjct: 618 TQELIEDLRKQLEHLQ 633
Score = 39.7 bits (91), Expect = 0.005
Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 19/169 (11%)
Query: 116 VIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT--------EVNRELKKLLVA 167
V+E K+ + +L+ +L+ L QL+ Q E R K+LL
Sbjct: 473 VLELEKDTAATGEQHSRLRQENLQLVHRANALEEQLKEQELRACEMVLEETRRQKELL-C 531
Query: 168 SVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMAD 227
+ + E L QL EN L T L +ER+ + + + D
Sbjct: 532 KMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEE----------KQKLLD 581
Query: 228 ELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSLQ 276
E+ + L + + L ER QF+++ ATQ+L+E+L L+
Sbjct: 582 EIESLTLRLSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLE 630
Score = 31.2 bits (69), Expect = 1.7
Identities = 45/227 (19%), Positives = 97/227 (42%), Gaps = 27/227 (11%)
Query: 65 LGKMLTEKAMEVKAVRILVPK-----AAITHDIPNKNTKVKSLGHHKGEFLGQSEGV-IE 118
L KM EK++E++ ++ + + + + P ++ L K + L + E + +
Sbjct: 530 LCKMEREKSIEIENLQTRLQQLDEENSELRSCTPCLKANIERLEEEKQKLLDEIESLTLR 589
Query: 119 PNKELSEVKNVLEKLKNSERRLLQDKEG---LSNQLRVQTE------VNRELKKLLVASV 169
++E + + ++L + + +DKE L LR Q E + E ++ +S+
Sbjct: 590 LSEEQENKRRMGDRLSHERHQFQRDKEATQELIEDLRKQLEHLQLLKLEAEQRRGRSSSM 649
Query: 170 GDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADEL 229
G +YH E Q + + RN + +E+L I + +K L S ++ L
Sbjct: 650 GLQ-EYHSRARESELEQEVRRLKQDNRNLKEQNEELNGQIITLSIQGAKSLFSTAFSESL 708
Query: 230 TNSRAALQRQNRDAHGAIQDLLSEREQFRQEM-IATQKLLEELLVSL 275
+++ R D L E Q ++E+ Q ++ ++V++
Sbjct: 709 AAEISSVSR----------DELMEAIQKQEEINFRLQDYIDRIIVAI 745
>gi|115527097 CDC42-binding protein kinase beta [Homo sapiens]
Length = 1711
Score = 40.8 bits (94), Expect = 0.002
Identities = 49/211 (23%), Positives = 87/211 (41%), Gaps = 19/211 (9%)
Query: 69 LTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKN 128
L +A E + R+ K ++ + V+SL H L S +KE+ ++
Sbjct: 438 LQMEAYERRIRRLEQEKLELSRKLQESTQTVQSL-HGSSRALSNSNR----DKEIKKLNE 492
Query: 129 VLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREK--NQ 186
+E+LKN + D L QL + +E + G + Q+ R +E+ Q
Sbjct: 493 EIERLKNK----IADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQEKEELHKQ 548
Query: 187 LILENEALGRNTAQLSE--QLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAH 244
L+ +E L +L + Q ++++Q +F EL + + RQ RD
Sbjct: 549 LVEASERLKSQAKELKDAHQQRKLALQ------EFSELNERMAELRAQKQKVSRQLRDKE 602
Query: 245 GAIQDLLSEREQFRQEMIATQKLLEELLVSL 275
++ + + RQEM +KL +EL L
Sbjct: 603 EEMEVATQKVDAMRQEMRRAEKLRKELEAQL 633
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 40.4 bits (93), Expect = 0.003
Identities = 60/285 (21%), Positives = 114/285 (40%), Gaps = 39/285 (13%)
Query: 22 DGMETEEPPKSVE-----VTSGVQSRKHHSLQSPWKKAVPSESPGVLQLGKMLTEKAMEV 76
D + EE K E + + + + HSLQ K + +L + E E+
Sbjct: 1076 DKQQIEEKLKKKEFELSQLQAKIDDEQVHSLQFQKK---------IKELQARIEELEEEI 1126
Query: 77 KAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNS 136
+A L +A I + +++ + E G + IE NK K +
Sbjct: 1127 EAEHTL--RAKIEKQRSDLARELEEISERLEEASGATSAQIEMNK----------KREAE 1174
Query: 137 ERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVG---DDLQYHFERLAREKNQLILENEA 193
+++ +D E + Q R+ + VA +G D+LQ ++L +EK++L +E +
Sbjct: 1175 FQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQKLEKEKSELKMEIDD 1234
Query: 194 LGRNTAQLSEQLERMSIQCDVWRSKFLASRV-------MADELTNSRAALQRQNRDAHGA 246
+ N LS+ + C +F + + +L +A LQ QN +
Sbjct: 1235 MASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNMQKARLQTQNGELSHR 1294
Query: 247 IQDLLSEREQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQPHS 291
+++ S Q + A + LEEL ++ E+T + + H+
Sbjct: 1295 VEEKESLISQLTKSKQALTQQLEELKRQME---EETKAKNAMAHA 1336
Score = 38.9 bits (89), Expect = 0.008
Identities = 39/215 (18%), Positives = 83/215 (38%), Gaps = 7/215 (3%)
Query: 74 MEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKL 133
+ ++ R+ ++H + K + + L K Q E + +E ++ KN +
Sbjct: 1277 LNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAKNAMAHA 1336
Query: 134 KNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASVGDDLQYHFERLAREKNQLILENEA 193
S R D + L Q + E EL++ L + + Q+ + + I E
Sbjct: 1337 LQSSR---HDCDLLREQYEEEQEAKAELQRALSKANSEVAQWR----TKYETDAIQRTEE 1389
Query: 194 LGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSE 253
L +L+++L+ + SK + L L R +H A L +
Sbjct: 1390 LEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKK 1449
Query: 254 REQFRQEMIATQKLLEELLVSLQWGREQTYSPSVQ 288
+ F + + ++ L+E L+ ++++ S S +
Sbjct: 1450 QRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTE 1484
Score = 33.1 bits (74), Expect = 0.46
Identities = 48/204 (23%), Positives = 84/204 (41%), Gaps = 38/204 (18%)
Query: 116 VIEPNKELSEVK-----------NVLE---KLKNSERRLLQDKEGLSNQLRVQT-EVNRE 160
VIE ++E+ ++K +VL+ + +N RL + EG N++ +Q NR+
Sbjct: 1580 VIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQ 1639
Query: 161 L---KKLLVASVGD--DLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVW 215
+ +K L G D Q H + R L + + R L E+LE M
Sbjct: 1640 MAETQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEM------- 1692
Query: 216 RSKFLASRVMADELTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVSL 275
+V ++ +R +++ DA +Q L S+ +I T+K LE +
Sbjct: 1693 -------KVALEQTERTRRLSEQELLDASDRVQLLHSQ----NTSLINTKKKLEADIAQC 1741
Query: 276 QWGREQTYSPSVQPHSTAELALTN 299
Q E + S A+ A+T+
Sbjct: 1742 QAEVENSIQESRNAEEKAKKAITD 1765
>gi|154350244 hypothetical protein LOC79632 isoform 2 [Homo sapiens]
Length = 971
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Query: 111 GQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASV- 169
GQ + E+ + +LE+L+ ++L++D EG N + Q+ REL L + +
Sbjct: 95 GQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLN--KAQSFYERELDTLKRSQLF 152
Query: 170 -GDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADE 228
+ LQ E+ A + + + L + +L +L+ + + K +
Sbjct: 153 TAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAI 212
Query: 229 LTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEE 270
N+ LQ+Q DA LLS+ ++ E+ A ++ L++
Sbjct: 213 AENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQ 254
>gi|154350226 hypothetical protein LOC79632 isoform 1 [Homo sapiens]
Length = 1140
Score = 40.4 bits (93), Expect = 0.003
Identities = 36/162 (22%), Positives = 72/162 (44%), Gaps = 4/162 (2%)
Query: 111 GQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELKKLLVASV- 169
GQ + E+ + +LE+L+ ++L++D EG N + Q+ REL L + +
Sbjct: 215 GQEKAEELHRMEVESLNKMLEELRLERKKLIEDYEGKLN--KAQSFYERELDTLKRSQLF 272
Query: 170 -GDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADE 228
+ LQ E+ A + + + L + +L +L+ + + K +
Sbjct: 273 TAESLQASKEKEADLRKEFQGQEAILRKTIGKLKTELQMVQDEAGSLLDKCQKLQTALAI 332
Query: 229 LTNSRAALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEE 270
N+ LQ+Q DA LLS+ ++ E+ A ++ L++
Sbjct: 333 AENNVQVLQKQLDDAKEGEMALLSKHKEVESELAAARERLQQ 374
>gi|114155142 nuclear pore complex-associated protein TPR [Homo
sapiens]
Length = 2363
Score = 40.0 bits (92), Expect = 0.004
Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 2/109 (1%)
Query: 103 GHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNRELK 162
G H+ + + E K LS + L + L + E L+NQL+ TE N+EL+
Sbjct: 41 GRHEKFKVESEQQYFEIEKRLSHSQERLVNETRECQSLRLELEKLNNQLKALTEKNKELE 100
Query: 163 KLLVASVGDDLQY--HFERLAREKNQLILENEALGRNTAQLSEQLERMS 209
++ Q+ E L EK LI NE L + L+E ++R++
Sbjct: 101 IAQDRNIAIQSQFTRTKEELEAEKRDLIRTNERLSQELEYLTEDVKRLN 149
Score = 37.4 bits (85), Expect = 0.024
Identities = 32/121 (26%), Positives = 54/121 (44%), Gaps = 17/121 (14%)
Query: 100 KSLGHHKGEFLGQSEGVIEPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQ-TEVN 158
K+L + E E ++ ELS + R+ LQD+ QLR Q TE
Sbjct: 1502 KTLSEKETEARNLQEQTVQLQSELSRL-----------RQDLQDRTTQEEQLRQQITEKE 1550
Query: 159 RELKKLLVASVGDDLQYHFERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSK 218
+ +K +VA+ + LA K+QL ENE L + L +Q + + ++ +S+
Sbjct: 1551 EKTRKAIVAA-----KSKIAHLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQ 1605
Query: 219 F 219
+
Sbjct: 1606 Y 1606
Score = 35.8 bits (81), Expect = 0.070
Identities = 61/269 (22%), Positives = 114/269 (42%), Gaps = 52/269 (19%)
Query: 116 VIEPNKELSEVKN---------VLEKLKNSE-----RRLLQDKEGLSNQLRVQTEVNREL 161
+++P +L+E+ N +LEKL+N ++++ E + L+ Q E
Sbjct: 388 IVKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERA 447
Query: 162 KKLLVASVGDDLQYHFERLAR--------EKNQLILE--NEALGRNTAQLSEQLERMSIQ 211
+K VAS+ L+ + + R K +LE N + LS+Q+ + ++
Sbjct: 448 QKA-VASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLME 506
Query: 212 CDVWRSKFL-------------ASRVMADELTNSR--AALQRQNRDAHGAIQDLLSEREQ 256
+ R + +S V++ L + R LQ+QN+ A+++L RE+
Sbjct: 507 LEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLLVALRELGETRER 566
Query: 257 FRQEMIAT-----QKLLEELLVSLQWGRE------QTYSPSVQPHSTAELALTNHK-LAK 304
QE ++ Q LE L L+ R+ Q V+ + L+ +A
Sbjct: 567 EEQETTSSKITELQLKLESALTELEQLRKSRQHQMQLVDSIVRQRDMYRILLSQTTGVAI 626
Query: 305 AVNSHLLGNVGINNQKKIPSTVEFCSTPA 333
+++ L +V + + K PST + STPA
Sbjct: 627 PLHASSLDDVSLASTPKRPSTSQTVSTPA 655
Score = 33.1 bits (74), Expect = 0.46
Identities = 44/238 (18%), Positives = 101/238 (42%), Gaps = 46/238 (19%)
Query: 58 ESPGVLQLGKMLTEKAMEVKAVRILVPKAAITHDIPNKNTKVKSLGHHKGEFLGQSEGVI 117
+ P + K+L+EK + K ++ L + +G K E +
Sbjct: 1347 KDPDTEEYRKLLSEKEVHTKRIQQLT----------------EEIGRLKAE-------IA 1383
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQT-EVNRELKKLL-VASVGDDLQY 175
N L+ +N+++ LK ++ +KE + L + ++ ++K + V +G +
Sbjct: 1384 RSNASLTNNQNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKT 1443
Query: 176 HFERLAREKNQLILENEALGRN-------TAQLSEQLERMSIQCDVWRSKFLASRV---- 224
+E L ++++ ++E A + Q ++L+ Q + +SK L S+V
Sbjct: 1444 QYEELKAQQDK-VMETSAQSSGDHQEQHVSVQEMQELKETLNQAET-KSKSLESQVENLQ 1501
Query: 225 --MADELTNSR------AALQRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEELLVS 274
++++ T +R LQ + +QD ++ EQ RQ++ ++ + +V+
Sbjct: 1502 KTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQEEQLRQQITEKEEKTRKAIVA 1559
Score = 32.7 bits (73), Expect = 0.60
Identities = 36/154 (23%), Positives = 64/154 (41%), Gaps = 13/154 (8%)
Query: 118 EPNKELSEVKNVLEKLKNSERRLLQDKEGLSNQLRVQTEVNR-ELKKLLVASVGDDLQYH 176
E NK V+N LEK ++ + +G + +V++E E++K L S Q
Sbjct: 13 ELNKLPKSVQNKLEKFLADQQSEIDGLKGRHEKFKVESEQQYFEIEKRLSHS-----QER 67
Query: 177 FERLAREKNQLILENEALGRNTAQLSEQLERMSIQCDVWRSKFLASRVMADELTNSRAAL 236
RE L LE E L L+E+ + + I D + + + T ++ L
Sbjct: 68 LVNETRECQSLRLELEKLNNQLKALTEKNKELEIAQD-------RNIAIQSQFTRTKEEL 120
Query: 237 QRQNRDAHGAIQDLLSEREQFRQEMIATQKLLEE 270
+ + RD + L E E +++ + L+E
Sbjct: 121 EAEKRDLIRTNERLSQELEYLTEDVKRLNEKLKE 154
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.357
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,906,613
Number of Sequences: 37866
Number of extensions: 596890
Number of successful extensions: 2817
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 288
Number of HSP's that attempted gapping in prelim test: 2355
Number of HSP's gapped (non-prelim): 692
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.