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Search of human proteins with 4504697
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504697 inhibin alpha subunit precursor [Homo sapiens]
(366 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504697 inhibin alpha subunit precursor [Homo sapiens] 764 0.0
gi|13899338 activin beta E [Homo sapiens] 65 1e-10
gi|126507087 bone morphogenetic protein 3 preproprotein [Homo sa... 61 2e-09
gi|110349792 growth differentiation factor 1 [Homo sapiens] 57 2e-08
gi|48475062 growth differentiation factor 6 precursor [Homo sapi... 57 3e-08
gi|4826740 growth differentiation factor 10 precursor [Homo sapi... 55 8e-08
gi|10190670 growth differentiation factor 3 precursor [Homo sapi... 53 5e-07
gi|7656928 bone morphogenetic protein 10 preproprotein [Homo sap... 51 1e-06
gi|61835232 growth differentiation factor 7 preproprotein [Homo ... 51 2e-06
gi|4504699 inhibin beta A precursor [Homo sapiens] 50 3e-06
gi|157276597 bone morphogenetic protein 4 preproprotein [Homo sa... 49 5e-06
gi|157276595 bone morphogenetic protein 4 preproprotein [Homo sa... 49 5e-06
gi|157276593 bone morphogenetic protein 4 preproprotein [Homo sa... 49 5e-06
gi|4503969 growth differentiation factor 5 preproprotein [Homo s... 49 5e-06
gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens] 49 9e-06
gi|5031795 inhibin beta C chain preproprotein [Homo sapiens] 49 9e-06
gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens] 48 2e-05
gi|4502425 bone morphogenetic protein 6 preproprotein [Homo sapi... 47 2e-05
gi|222352098 nodal precursor [Homo sapiens] 47 3e-05
gi|7705308 growth differentiation factor 2 [Homo sapiens] 47 3e-05
gi|29571106 bone morphogenetic protein 8B preproprotein [Homo sa... 47 3e-05
gi|4557369 bone morphogenetic protein 2 preproprotein [Homo sapi... 46 6e-05
gi|4885261 growth differentiation factor 9 precursor [Homo sapiens] 46 6e-05
gi|145611428 bone morphogenetic protein 8A [Homo sapiens] 46 6e-05
gi|10835091 bone morphogenetic protein 5 preproprotein [Homo sap... 45 8e-05
gi|5031613 growth differentiation factor 11 precursor [Homo sapi... 45 1e-04
gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens] 44 2e-04
gi|4885259 myostatin [Homo sapiens] 44 2e-04
gi|153792495 growth differentiation factor 15 [Homo sapiens] 41 0.001
gi|239757187 PREDICTED: similar to growth differentiation factor... 41 0.001
>gi|4504697 inhibin alpha subunit precursor [Homo sapiens]
Length = 366
Score = 764 bits (1974), Expect = 0.0
Identities = 366/366 (100%), Positives = 366/366 (100%)
Query: 1 MVLHLLLFLLLTPQGGHSCQGLELARELVLAKVRALFLDALGPPAVTREGGDPGVRRLPR 60
MVLHLLLFLLLTPQGGHSCQGLELARELVLAKVRALFLDALGPPAVTREGGDPGVRRLPR
Sbjct: 1 MVLHLLLFLLLTPQGGHSCQGLELARELVLAKVRALFLDALGPPAVTREGGDPGVRRLPR 60
Query: 61 RHALGGFTHRGSEPEEEEDVSQAILFPATDASCEDKSAARGLAQEAEEGLFRYMFRPSQH 120
RHALGGFTHRGSEPEEEEDVSQAILFPATDASCEDKSAARGLAQEAEEGLFRYMFRPSQH
Sbjct: 61 RHALGGFTHRGSEPEEEEDVSQAILFPATDASCEDKSAARGLAQEAEEGLFRYMFRPSQH 120
Query: 121 TRSRQVTSAQLWFHTGLDRQGTAASNSSEPLLGLLALSPGGPVAVPMSLGHAPPHWAVLH 180
TRSRQVTSAQLWFHTGLDRQGTAASNSSEPLLGLLALSPGGPVAVPMSLGHAPPHWAVLH
Sbjct: 121 TRSRQVTSAQLWFHTGLDRQGTAASNSSEPLLGLLALSPGGPVAVPMSLGHAPPHWAVLH 180
Query: 181 LATSALSLLTHPVLVLLLRCPLCTCSARPEATPFLVAHTRTRPPSGGERARRSTPLMSWP 240
LATSALSLLTHPVLVLLLRCPLCTCSARPEATPFLVAHTRTRPPSGGERARRSTPLMSWP
Sbjct: 181 LATSALSLLTHPVLVLLLRCPLCTCSARPEATPFLVAHTRTRPPSGGERARRSTPLMSWP 240
Query: 241 WSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP 300
WSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP
Sbjct: 241 WSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP 300
Query: 301 PNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLT 360
PNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLT
Sbjct: 301 PNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLT 360
Query: 361 QHCACI 366
QHCACI
Sbjct: 361 QHCACI 366
>gi|13899338 activin beta E [Homo sapiens]
Length = 350
Score = 64.7 bits (156), Expect = 1e-10
Identities = 64/208 (30%), Positives = 83/208 (39%), Gaps = 44/208 (21%)
Query: 176 WAVLHLATSALSLLTHPVLVLLLRC-PL---CTCSARPEAT--------PFLVAHTRTRP 223
W L L +S L VL L L C PL T + +P PFL R
Sbjct: 168 WHTLTLPSSGLRGEKSGVLKLQLDCRPLEGNSTVTGQPRRLLDTAGHQQPFLELKIRANE 227
Query: 224 PSGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYP 283
P G RARR TP EPA C R + FQELGW WI+ P
Sbjct: 228 PGAG-RARRRTPTC-----------------EPATPLCCRRDHY-VDFQELGWRDWILQP 268
Query: 284 PSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL------PGAQPCCAALPGTMRP 337
+ +YC G C PP+L+ A + +SLL P + CC +P RP
Sbjct: 269 EGYQLNYCSGQC----PPHLAGSPGIAASFHSAVFSLLKANNPWPASTSCC--VPTARRP 322
Query: 338 LHVRTTSDGGYSFKYETVPNLLTQHCAC 365
L + G K + VP+++ + C C
Sbjct: 323 LSLLYLDHNGNVVKTD-VPDMVVEACGC 349
>gi|126507087 bone morphogenetic protein 3 preproprotein [Homo
sapiens]
Length = 472
Score = 60.8 bits (146), Expect = 2e-09
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 4/106 (3%)
Query: 261 NCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSL 320
NC R L + F ++GW WI+ P SF +YC G C +P +L + + +
Sbjct: 369 NCARRYLKVDFADIGWSEWIISPKSFDAYYCSGACQFPMPKSLKPSNHATIQSIVRAVGV 428
Query: 321 LPG-AQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+PG +PCC +P M L + D + + PN+ + CAC
Sbjct: 429 VPGIPEPCC--VPEKMSSLSI-LFFDENKNVVLKVYPNMTVESCAC 471
>gi|110349792 growth differentiation factor 1 [Homo sapiens]
Length = 372
Score = 57.4 bits (137), Expect = 2e-08
Identities = 36/114 (31%), Positives = 54/114 (47%), Gaps = 19/114 (16%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPT------PA 315
C L +SF+E+GW RW++ P F+ +YC G C L + +L G PP A
Sbjct: 267 CRARRLYVSFREVGWHRWVIAPRGFLANYCQGQCALPV----ALSGSGGPPALNHAVLRA 322
Query: 316 QPYSLLPGAQ--PCCAALPGTMRPLHVR--TTSDGGYSFKYETVPNLLTQHCAC 365
++ PGA PCC +P + P+ V SD +YE +++ C C
Sbjct: 323 LMHAAAPGAADLPCC--VPARLSPISVLFFDNSDNVVLRQYE---DMVVDECGC 371
>gi|48475062 growth differentiation factor 6 precursor [Homo
sapiens]
Length = 455
Score = 57.0 bits (136), Expect = 3e-08
Identities = 38/151 (25%), Positives = 64/151 (42%), Gaps = 19/151 (12%)
Query: 223 PPSGGERARRSTPLMSWPWSPSALRLLQRPP--------EEPAAHANCHRVALNISFQEL 274
PPSG AR PW PS R +R + C + L+++F+EL
Sbjct: 315 PPSGAPDAR--------PWLPSPGRRRRRTAFASRHGKRHGKKSRLRCSKKPLHVNFKEL 366
Query: 275 GWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGT 334
GW+ WI+ P + ++C G C + +L T S+ PG+ P +P
Sbjct: 367 GWDDWIIAPLEYEAYHCEGVCDFPLRSHLEPTNHAIIQTLMN--SMDPGSTPPSCCVPTK 424
Query: 335 MRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+ P+ + D G + Y+ +++ + C C
Sbjct: 425 LTPISI-LYIDAGNNVVYKQYEDMVVESCGC 454
>gi|4826740 growth differentiation factor 10 precursor [Homo
sapiens]
Length = 478
Score = 55.5 bits (132), Expect = 8e-08
Identities = 31/105 (29%), Positives = 47/105 (44%), Gaps = 4/105 (3%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL 321
C R L + F ++GW WI+ P SF +YC G C +P + + + ++
Sbjct: 376 CSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGII 435
Query: 322 PG-AQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
PG +PCC +P M L V D + + PN+ CAC
Sbjct: 436 PGIPEPCC--VPDKMNSLGV-LFLDENRNVVLKVYPNMSVDTCAC 477
>gi|10190670 growth differentiation factor 3 precursor [Homo
sapiens]
Length = 364
Score = 52.8 bits (125), Expect = 5e-07
Identities = 23/62 (37%), Positives = 35/62 (56%)
Query: 243 PSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPN 302
PS R P + + CHR L I+F++LGW +WI+ P F+ +YCHG C + +
Sbjct: 245 PSRKRRAAIPVPKLSCKNLCHRHQLFINFRDLGWHKWIIAPKGFMANYCHGECPFSLTIS 304
Query: 303 LS 304
L+
Sbjct: 305 LN 306
>gi|7656928 bone morphogenetic protein 10 preproprotein [Homo
sapiens]
Length = 424
Score = 51.2 bits (121), Expect = 1e-06
Identities = 28/106 (26%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL 321
C R L I F+E+GW+ WI+ PP + + C G C + +L+ +
Sbjct: 323 CKRTPLYIDFKEIGWDSWIIAPPGYEAYECRGVCNYPLAEHLTPTKHAIIQALVHLKNSQ 382
Query: 322 PGAQPCCAALPGTMRPLHVRTTSDG--GYSFKYETVPNLLTQHCAC 365
++ CC +P + P+ + G Y FKYE + C C
Sbjct: 383 KASKACC--VPTKLEPISILYLDKGVVTYKFKYE---GMAVSECGC 423
>gi|61835232 growth differentiation factor 7 preproprotein [Homo
sapiens]
Length = 450
Score = 50.8 bits (120), Expect = 2e-06
Identities = 26/106 (24%), Positives = 48/106 (45%), Gaps = 3/106 (2%)
Query: 260 ANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYS 319
+ C R L++ F+ELGW+ WI+ P + ++C G C + +L T S
Sbjct: 347 SRCSRKPLHVDFKELGWDDWIIAPLDYEAYHCEGLCDFPLRSHLEPTNHAIIQTLLN--S 404
Query: 320 LLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+ P A P +P + P+ + D + Y+ +++ + C C
Sbjct: 405 MAPDAAPASCCVPARLSPISI-LYIDAANNVVYKQYEDMVVEACGC 449
>gi|4504699 inhibin beta A precursor [Homo sapiens]
Length = 426
Score = 50.1 bits (118), Expect = 3e-06
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIP----PNLSLPVPGAPPTPAQP 317
C + +SF+++GW WI+ P + +YC G C HI +LS +
Sbjct: 321 CCKKQFFVSFKDIGWNDWIIAPSGYHANYCEGECPSHIAGTSGSSLSFHSTVINHYRMRG 380
Query: 318 YSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+S + CC +P +RP+ + DG K + + N++ + C C
Sbjct: 381 HSPFANLKSCC--VPTKLRPMSMLYYDDGQNIIK-KDIQNMIVEECGC 425
>gi|157276597 bone morphogenetic protein 4 preproprotein [Homo
sapiens]
Length = 408
Score = 49.3 bits (116), Expect = 5e-06
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 247 RLLQRPPEEPAAHA-----NCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPP 301
R +R P+ + A NC R +L + F ++GW WIV PP + YCHG C +
Sbjct: 288 RRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLAD 347
Query: 302 NLS 304
+L+
Sbjct: 348 HLN 350
>gi|157276595 bone morphogenetic protein 4 preproprotein [Homo
sapiens]
Length = 408
Score = 49.3 bits (116), Expect = 5e-06
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 247 RLLQRPPEEPAAHA-----NCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPP 301
R +R P+ + A NC R +L + F ++GW WIV PP + YCHG C +
Sbjct: 288 RRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLAD 347
Query: 302 NLS 304
+L+
Sbjct: 348 HLN 350
>gi|157276593 bone morphogenetic protein 4 preproprotein [Homo
sapiens]
Length = 408
Score = 49.3 bits (116), Expect = 5e-06
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 247 RLLQRPPEEPAAHA-----NCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPP 301
R +R P+ + A NC R +L + F ++GW WIV PP + YCHG C +
Sbjct: 288 RRAKRSPKHHSQRARKKNKNCRRHSLYVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLAD 347
Query: 302 NLS 304
+L+
Sbjct: 348 HLN 350
>gi|4503969 growth differentiation factor 5 preproprotein [Homo
sapiens]
Length = 501
Score = 49.3 bits (116), Expect = 5e-06
Identities = 30/124 (24%), Positives = 55/124 (44%), Gaps = 5/124 (4%)
Query: 242 SPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPP 301
+P A R +RP + A C R AL+++F+++GW+ WI+ P + +C G C P
Sbjct: 382 APLATRQGKRPSKN--LKARCSRKALHVNFKDMGWDDWIIAPLEYEAFHCEGLC--EFPL 437
Query: 302 NLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQ 361
L S+ P + P +P + P+ + D + Y+ +++ +
Sbjct: 438 RSHLEPTNHAVIQTLMNSMDPESTPPTCCVPTRLSPISI-LFIDSANNVVYKQYEDMVVE 496
Query: 362 HCAC 365
C C
Sbjct: 497 SCGC 500
>gi|154813204 inhibin beta B subunit preproprotein [Homo sapiens]
Length = 407
Score = 48.5 bits (114), Expect = 9e-06
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 16/147 (10%)
Query: 227 GERARRSTPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSF 286
GE + R ++ S R+ +R E C R I F+ +GW WI+ P +
Sbjct: 268 GEESHRPFVVVQARLGDSRHRIRKRGLECDGRTNLCCRQQFFIDFRLIGWNDWIIAPTGY 327
Query: 287 IFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGAQPCCAALPGTMR----PLHVRT 342
+YC G C ++ G P + + ++ + PGT+ P + T
Sbjct: 328 YGNYCEGSCPAYL--------AGVPGSASSFHTAVVNQYRMRGLNPGTVNSCCIPTKLST 379
Query: 343 TS----DGGYSFKYETVPNLLTQHCAC 365
S D Y+ VPN++ + C C
Sbjct: 380 MSMLYFDDEYNIVKRDVPNMIVEECGC 406
>gi|5031795 inhibin beta C chain preproprotein [Homo sapiens]
Length = 352
Score = 48.5 bits (114), Expect = 9e-06
Identities = 93/388 (23%), Positives = 139/388 (35%), Gaps = 69/388 (17%)
Query: 5 LLLFLLL------TPQGGHSCQG-------LELARELVLAKVRALFLDALGPPAVTREGG 51
LL FLLL TP+ G C LE REL+L + LD L +T+
Sbjct: 6 LLAFLLLAPTTVATPRAGGQCPACGGPTLELESQRELLLDLAKRSILDKLH---LTQR-- 60
Query: 52 DPGVRRLPRRHALG-GFTHRGSEPEEEEDVSQAILFPATDASCEDKSAARGLAQEAEEGL 110
P + R R AL H P+ A+L + CE S A +
Sbjct: 61 -PTLNRPVSRAALRTALQHLHGVPQG------ALLEDNREQECEIISFAETGLSTINQTR 113
Query: 111 FRYMFRPSQHTRSRQVTSAQLWFHTGLDRQGTAASNSSEPL-LGLLALSPGGP---VAVP 166
+ F + R+V A L F L SN++ L + +L L P +A
Sbjct: 114 LDFHFSSDRTAGDREVQQASLMFFVQLP------SNTTWTLKVRVLVLGPHNTNLTLATQ 167
Query: 167 MSLGHAPPHWAVLHLATSALSLLT--HPVLVLLLRCPLCTCSA---RPEATPFLVAHTRT 221
L W L L A + + H L L+L + S PF+ A R
Sbjct: 168 YLLEVDASGWHQLPLGPEAQAACSQGHLTLELVLEGQVAQSSVILGGAAHRPFVAARVRV 227
Query: 222 RPPSGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIV 281
GG+ ++ +R + C R + F+E+GW WI+
Sbjct: 228 ----GGKH-----------------QIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWII 266
Query: 282 YPPSFIFHYCHGGCGLHIP--PNLSLPVPGAPPT--PAQPYSLLPGAQPCCAALPGTMRP 337
P + ++C G C LHI P ++ A A + G CC +P RP
Sbjct: 267 QPEGYAMNFCIGQCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCC--VPTARRP 324
Query: 338 LHVRTTSDGGYSFKYETVPNLLTQHCAC 365
L + D + +P+++ + C C
Sbjct: 325 LSL-LYYDRDSNIVKTDIPDMVVEACGC 351
>gi|4502427 bone morphogenetic protein 7 precursor [Homo sapiens]
Length = 431
Score = 47.8 bits (112), Expect = 2e-05
Identities = 38/161 (23%), Positives = 66/161 (40%), Gaps = 13/161 (8%)
Query: 213 PFLVA-------HTRTRPPSGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHAN-CHR 264
PF+VA H R+ +G ++ RS P + ALR+ + C +
Sbjct: 275 PFMVAFFKATEVHFRSIRSTGSKQ--RSQNRSKTPKNQEALRMANVAENSSSDQRQACKK 332
Query: 265 VALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGA 324
L +SF++LGW+ WI+ P + +YC G C + ++ T +
Sbjct: 333 HELYVSFRDLGWQDWIIAPEGYAAYYCEGECAFPLNSYMNATNHAIVQTLVHFINPETVP 392
Query: 325 QPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+PCCA P + + V D + + N++ + C C
Sbjct: 393 KPCCA--PTQLNAISVLYFDDSS-NVILKKYRNMVVRACGC 430
>gi|4502425 bone morphogenetic protein 6 preproprotein [Homo
sapiens]
Length = 513
Score = 47.4 bits (111), Expect = 2e-05
Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 3/104 (2%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL 321
C + L +SFQ+LGW+ WI+ P + +YC G C + +++ T +
Sbjct: 412 CRKHELYVSFQDLGWQDWIIAPKGYAANYCDGECSFPLNAHMNATNHAIVQTLVHLMNPE 471
Query: 322 PGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+PCCA P + + V D + + N++ + C C
Sbjct: 472 YVPKPCCA--PTKLNAISVLYFDDNS-NVILKKYRNMVVRACGC 512
>gi|222352098 nodal precursor [Homo sapiens]
Length = 347
Score = 47.0 bits (110), Expect = 3e-05
Identities = 37/138 (26%), Positives = 53/138 (38%), Gaps = 25/138 (18%)
Query: 237 MSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCG 296
+SW W R P C +V + F +GW WI+YP + + C G C
Sbjct: 227 LSWEWGKR-----HRRHHLPDRSQLCRKVKFQVDFNLIGWGSWIIYPKQYNAYRCEGEC- 280
Query: 297 LHIPPNLSLPVPGA--PPTPAQPYSLLPGAQP------CCAALPGTMRPLHVRTTSDGGY 348
PN PV P A SLL QP CCA P +PL + +G
Sbjct: 281 ----PN---PVGEEFHPTNHAYIQSLLKRYQPHRVPSTCCA--PVKTKPLSMLYVDNGRV 331
Query: 349 SFKYETVPNLLTQHCACI 366
+ +++ + C C+
Sbjct: 332 LLDHH--KDMIVEECGCL 347
>gi|7705308 growth differentiation factor 2 [Homo sapiens]
Length = 429
Score = 47.0 bits (110), Expect = 3e-05
Identities = 25/117 (21%), Positives = 47/117 (40%), Gaps = 2/117 (1%)
Query: 249 LQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVP 308
L R A ++C + +L ++F+++GW+ WI+ P + + C GGC + +++
Sbjct: 314 LARRKRSAGAGSHCQKTSLRVNFEDIGWDSWIIAPKEYEAYECKGGCFFPLADDVTPTKH 373
Query: 309 GAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
T + CC +P + P+ V D G + C C
Sbjct: 374 AIVQTLVHLKFPTKVGKACC--VPTKLSPISVLYKDDMGVPTLKYHYEGMSVAECGC 428
>gi|29571106 bone morphogenetic protein 8B preproprotein [Homo
sapiens]
Length = 402
Score = 47.0 bits (110), Expect = 3e-05
Identities = 44/166 (26%), Positives = 64/166 (38%), Gaps = 23/166 (13%)
Query: 213 PFLVAHTRTRP-----PSGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHAN--CHRV 265
PF+V R P P RR P S P A RL + +H C R
Sbjct: 246 PFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNEL-PQANRLPGIFDDVHGSHGRQVCRRH 304
Query: 266 ALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGAQ 325
L +SFQ+LGW W++ P + +YC G C P + + + + ++P A
Sbjct: 305 ELYVSFQDLGWLDWVIAPQGYSAYYCEGECS--FPLDSCMNATNHAILQSLVHLMMPDAV 362
Query: 326 P--CCAALPGTMRPLHVRTTS----DGGYSFKYETVPNLLTQHCAC 365
P CCA P + TS D + N++ + C C
Sbjct: 363 PKACCA-------PTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401
>gi|4557369 bone morphogenetic protein 2 preproprotein [Homo
sapiens]
Length = 396
Score = 45.8 bits (107), Expect = 6e-05
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 260 ANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLS 304
++C R L + F ++GW WIV PP + YCHG C + +L+
Sbjct: 294 SSCKRHPLYVDFSDVGWNDWIVAPPGYHAFYCHGECPFPLADHLN 338
>gi|4885261 growth differentiation factor 9 precursor [Homo sapiens]
Length = 454
Score = 45.8 bits (107), Expect = 6e-05
Identities = 33/128 (25%), Positives = 49/128 (38%), Gaps = 7/128 (5%)
Query: 240 PWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHI 299
P P++ L + + C +SF +L W+ WIV P + YC G C +
Sbjct: 331 PLGPASFNLSEYFRQFLLPQNECELHDFRLSFSQLKWDNWIVAPHRYNPRYCKGDCPRAV 390
Query: 300 PPNLSLPVPGAPPTPAQP--YSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPN 357
PV T Q Y L + P + +P PL V T G S Y+ +
Sbjct: 391 GHRYGSPV----HTMVQNIIYEKLDSSVPRPSCVPAKYSPLSVLTIEPDG-SIAYKEYED 445
Query: 358 LLTQHCAC 365
++ C C
Sbjct: 446 MIATKCTC 453
>gi|145611428 bone morphogenetic protein 8A [Homo sapiens]
Length = 402
Score = 45.8 bits (107), Expect = 6e-05
Identities = 44/166 (26%), Positives = 63/166 (37%), Gaps = 23/166 (13%)
Query: 213 PFLVAHTRTRP-----PSGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHAN--CHRV 265
PF+V R P P RR P S P A RL + +H C R
Sbjct: 246 PFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNEL-PQANRLPGIFDDVRGSHGRQVCRRH 304
Query: 266 ALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLLPGAQ 325
L +SFQ+LGW W++ P + +YC G C P + + + + + P A
Sbjct: 305 ELYVSFQDLGWLDWVIAPQGYSAYYCEGECS--FPLDSCMNATNHAILQSLVHLMKPNAV 362
Query: 326 P--CCAALPGTMRPLHVRTTS----DGGYSFKYETVPNLLTQHCAC 365
P CCA P + TS D + N++ + C C
Sbjct: 363 PKACCA-------PTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401
>gi|10835091 bone morphogenetic protein 5 preproprotein [Homo
sapiens]
Length = 454
Score = 45.4 bits (106), Expect = 8e-05
Identities = 27/106 (25%), Positives = 45/106 (42%), Gaps = 7/106 (6%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL 321
C + L +SF++LGW+ WI+ P + YC G C P N + + +
Sbjct: 353 CKKHELYVSFRDLGWQDWIIAPEGYAAFYCDGECS--FPLNAHMNATNHAIVQTLVHLMF 410
Query: 322 PG--AQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
P +PCCA P + + V D + + N++ + C C
Sbjct: 411 PDHVPKPCCA--PTKLNAISVLYFDDSS-NVILKKYRNMVVRSCGC 453
>gi|5031613 growth differentiation factor 11 precursor [Homo
sapiens]
Length = 407
Score = 44.7 bits (104), Expect = 1e-04
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 16/115 (13%)
Query: 254 EEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCG---LHIPPNLSLPVPGA 310
+E ++ + C R L + F+ GW+ WI+ P + +YC G C + P+ L V A
Sbjct: 305 DEHSSESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGQCEYMFMQKYPHTHL-VQQA 362
Query: 311 PPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
P + A PCC P M P+++ +D Y +P ++ C C
Sbjct: 363 NPRGS--------AGPCCT--PTKMSPINMLYFND-KQQIIYGKIPGMVVDRCGC 406
>gi|4885097 bone morphogenetic protein 15 precursor [Homo sapiens]
Length = 392
Score = 44.3 bits (103), Expect = 2e-04
Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 3/104 (2%)
Query: 262 CHRVALNISFQELGWERWIVYPPSFIFHYCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL 321
C ISF++LGW+ WI+ PP + +YC G C + L+ P L+
Sbjct: 291 CSLHPFQISFRQLGWDHWIIAPPFYTPNYCKGTCLRVLRDGLNSPNHAIIQNLIN--QLV 348
Query: 322 PGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
+ P + +P P+ V G S Y+ ++ + C C
Sbjct: 349 DQSVPRPSCVPYKYVPISVLMIEANG-SILYKEYEGMIAESCTC 391
>gi|4885259 myostatin [Homo sapiens]
Length = 375
Score = 43.9 bits (102), Expect = 2e-04
Identities = 32/115 (27%), Positives = 50/115 (43%), Gaps = 16/115 (13%)
Query: 254 EEPAAHANCHRVALNISFQELGWERWIVYPPSFIFHYCHGGCG---LHIPPNLSLPVPGA 310
+E + + C R L + F+ GW+ WI+ P + +YC G C L P+ L V A
Sbjct: 273 DEHSTESRCCRYPLTVDFEAFGWD-WIIAPKRYKANYCSGECEFVFLQKYPHTHL-VHQA 330
Query: 311 PPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCAC 365
P + A PCC P M P+++ +G Y +P ++ C C
Sbjct: 331 NPRGS--------AGPCCT--PTKMSPINM-LYFNGKEQIIYGKIPAMVVDRCGC 374
>gi|153792495 growth differentiation factor 15 [Homo sapiens]
Length = 308
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/178 (24%), Positives = 62/178 (34%), Gaps = 35/178 (19%)
Query: 207 ARPEATPFLVAHTRTRPPSGGE-----RARRSTPLMSWPWSPSALRLLQRPPEEPAAHAN 261
ARP+A H R PP + + P + P A R +R H
Sbjct: 148 ARPQAPAL---HLRLSPPPSQSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCP 204
Query: 262 ------CHRVALNISFQELGWERWIVYPPSFIFHYCHGGC-------GLHIPPNLSLPVP 308
C + S ++LGW W++ P C G C +H SL
Sbjct: 205 LGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRL 264
Query: 309 GAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCACI 366
PA PCC +P + P+ + +D G S +T +LL + C CI
Sbjct: 265 KPDTVPA----------PCC--VPASYNPMVLIQKTDTGVSL--QTYDDLLAKDCHCI 308
>gi|239757187 PREDICTED: similar to growth differentiation factor 15
[Homo sapiens]
Length = 270
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/178 (24%), Positives = 62/178 (34%), Gaps = 35/178 (19%)
Query: 207 ARPEATPFLVAHTRTRPPSGGE-----RARRSTPLMSWPWSPSALRLLQRPPEEPAAHAN 261
ARP+A H R PP + + P + P A R +R H
Sbjct: 110 ARPQAPAL---HLRLSPPPSQSDQLLAESSSARPQLELHLRPQAARGRRRARARNGDHCP 166
Query: 262 ------CHRVALNISFQELGWERWIVYPPSFIFHYCHGGC-------GLHIPPNLSLPVP 308
C + S ++LGW W++ P C G C +H SL
Sbjct: 167 LGPGRCCRLHTVRASLEDLGWADWVLSPREVQVTMCIGACPSQFRAANMHAQIKTSLHRL 226
Query: 309 GAPPTPAQPYSLLPGAQPCCAALPGTMRPLHVRTTSDGGYSFKYETVPNLLTQHCACI 366
PA PCC +P + P+ + +D G S +T +LL + C CI
Sbjct: 227 KPDTVPA----------PCC--VPASYNPMVLIQKTDTGVSL--QTYDDLLAKDCHCI 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,438,717
Number of Sequences: 37866
Number of extensions: 1032738
Number of successful extensions: 5185
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 4932
Number of HSP's gapped (non-prelim): 294
length of query: 366
length of database: 18,247,518
effective HSP length: 104
effective length of query: 262
effective length of database: 14,309,454
effective search space: 3749076948
effective search space used: 3749076948
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.