Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4504383
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4504383 HGF activator preproprotein [Homo sapiens]
(655 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4504383 HGF activator preproprotein [Homo sapiens] 1415 0.0
gi|145275213 coagulation factor XII precursor [Homo sapiens] 459 e-129
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi... 307 2e-83
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei... 294 2e-79
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein... 293 3e-79
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot... 277 2e-74
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa... 277 3e-74
gi|4505881 plasminogen [Homo sapiens] 208 1e-53
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens] 185 1e-46
gi|4506153 prostasin preproprotein [Homo sapiens] 185 1e-46
gi|170932492 transmembrane protease, serine 5 [Homo sapiens] 180 3e-45
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 167 2e-41
gi|33667063 transmembrane protease, serine 9 [Homo sapiens] 165 1e-40
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 163 5e-40
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 162 9e-40
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s... 160 3e-39
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho... 160 3e-39
gi|223942069 enterokinase precursor [Homo sapiens] 160 3e-39
gi|4503627 coagulation factor XI precursor [Homo sapiens] 160 5e-39
gi|4506115 protein C [Homo sapiens] 157 2e-38
gi|117956391 protease, serine, 33 [Homo sapiens] 157 2e-38
gi|11545839 protease, serine, 22 [Homo sapiens] 157 2e-38
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 157 3e-38
gi|4503635 coagulation factor II preproprotein [Homo sapiens] 156 6e-38
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 156 6e-38
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 156 6e-38
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-... 156 6e-38
gi|222831592 transmembrane protease, serine 7 [Homo sapiens] 155 1e-37
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 155 1e-37
gi|4506143 neurotrypsin precursor [Homo sapiens] 154 2e-37
>gi|4504383 HGF activator preproprotein [Homo sapiens]
Length = 655
Score = 1415 bits (3664), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 1 MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV 60
MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV
Sbjct: 1 MGRWAWVPSPWPPPGLGPFLLLLLLLLLLPRGFQPQPGGNRTESPEPNATATPAIPTILV 60
Query: 61 TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH 120
TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH
Sbjct: 61 TSVTSETPATSAPEAEGPQSGGLPPPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLH 120
Query: 121 ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD 180
ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD
Sbjct: 121 ACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAALDPCASGPCLNGGSCSNTQD 180
Query: 181 PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT 240
PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT
Sbjct: 181 PQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGT 240
Query: 241 RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST 300
RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST
Sbjct: 241 RHTACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST 300
Query: 301 SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE 360
SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE
Sbjct: 301 SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE 360
Query: 361 YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP 420
YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP
Sbjct: 361 YCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHP 420
Query: 421 WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE 480
WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE
Sbjct: 421 WLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIE 480
Query: 481 KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW 540
KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW
Sbjct: 481 KYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGW 540
Query: 541 GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG 600
GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG
Sbjct: 541 GHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGG 600
Query: 601 PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS 655
PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS
Sbjct: 601 PLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRPPRRLVAPS 655
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 459 bits (1181), Expect = e-129
Identities = 239/607 (39%), Positives = 326/607 (53%), Gaps = 65/607 (10%)
Query: 86 PPRAVPSSSSPQAQ----ALTEDGRPCRFPFRYGGRMLHACTSEGS-AHRKWCATTHNYD 140
PP P +A+ LT G PC FPF+Y ++ H CT +G + WCATT N+D
Sbjct: 21 PPWEAPKEHKYKAEEHTVVLTVTGEPCHFPFQYHRQLYHKCTHKGRPGPQPWCATTPNFD 80
Query: 141 RDRAWGYCVEATPPPGGPAALDPCAS-GPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGT 199
+D+ WGYC+E D C+ PC GG+C N P HC CP+ TG C
Sbjct: 81 QDQRWGYCLEPKK------VKDHCSKHSPCQKGGTCVNM--PSGPHCLCPQHLTGNHCQK 132
Query: 200 EKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLI 259
EKCF+ + + W R Q V +C+C G C+ AC ++PCL+GG C +
Sbjct: 133 EKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQACRTNPCLHGGRC--L 190
Query: 260 VATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQEL 319
G +C CP G+ G C+++ C+ G G YRG+A T+ SG C W S+ Y+ +
Sbjct: 191 EVEGHRLCHCPVGYTGAFCDVDTKASCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNV 250
Query: 320 HVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRV------ 373
+ A GLG HA+CRNPDND RPWC+V+ LSWEYC L C++ T+
Sbjct: 251 TAEQ---ARNWGLGGHAFCRNPDNDIRPWCFVLNRDRLSWEYCDLAQCQTPTQAAPPTPV 307
Query: 374 --QLSPDLLATLPEPASP-----------------------------GRQACGRRHKKRT 402
+L L+ P P P G +CG+R +K
Sbjct: 308 SPRLHVPLMPAQPAPPKPQPTTRTPPQSQTPGALPAKREQPPSLTRNGPLSCGQRLRKSL 367
Query: 403 FLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 462
R++GG +L G+HP++AA+Y G SFCAGSL+ CWV++AAHC P + ++VVL
Sbjct: 368 SSMTRVVGGLVALRGAHPYIAALYWGHSFCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVL 427
Query: 463 GQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSD--HDLVLIRLKKKGD-RCATRSQFVQP 519
GQ N + + QT + Y L+ F+P HDL L+RL++ D CA S +VQP
Sbjct: 428 GQERRNHSCEPCQTLAVRSY---RLHEAFSPVSYQHDLALLRLQEDADGSCALLSPYVQP 484
Query: 520 ICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISP 579
+CLP + CQ+AGWGH E Y+S L+EA VP ++ +CS+P+V+G+ I P
Sbjct: 485 VCLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGSSILP 544
Query: 580 NMLCAGYFDCKSDACQGDSGGPLACEKNGV---AYLYGIISWGDGCGRLHKPGVYTRVAN 636
MLCAG+ + +DACQGDSGGPL CE L GIISWG GCG +KPGVYT VA
Sbjct: 545 GMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGSGCGDRNKPGVYTDVAY 604
Query: 637 YVDWIND 643
Y+ WI +
Sbjct: 605 YLAWIRE 611
>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
sapiens]
Length = 560
Score = 307 bits (786), Expect = 2e-83
Identities = 178/498 (35%), Positives = 260/498 (52%), Gaps = 30/498 (6%)
Query: 162 DPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYEYLEGGDRWARVR 221
DPC PC +GG C ++ CSC F+G C + T + G + +
Sbjct: 75 DPCQPNPCEHGGDC--LVHGSTFTCSCLAPFSGNKC---QKVQNTCKDNPCGRGQCLITQ 129
Query: 222 QGHVEQCECFGGRTWCEGTRHT-ACLSSPCLNGGTCHLIVATGTTVCACPPGFAGRLCNI 280
+C C T ++ C +PC NG TC CACP F G+ C I
Sbjct: 130 SPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEI 189
Query: 281 EPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRN 340
D+ C++G+G YRG + + + +CL WNS LL QE + + A G+G H +CRN
Sbjct: 190 GSDD-CYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRN 248
Query: 341 PDNDERPWCYV-VKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGRRHK 399
PD DE+PWC++ V + + WEYC + AC + + P+ T P PG +CG+
Sbjct: 249 PDADEKPWCFIKVTNDKVKWEYCDVSACSA--QDVAYPEESPTEPSTKLPGFDSCGKTEI 306
Query: 400 KRTFLRPRIIGGSSSLPGSHPWLAAIYIG---------DSFCAGSLVHTCWVVSAAHCFS 450
++ RI GG S G HPW A++ FC G+L+H CWV++AAHC
Sbjct: 307 AERKIK-RIYGGFKSTAGKHPWQASLQSSLPLTISMPQGHFCGGALIHPCWVLTAAHCTD 365
Query: 451 HSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH-DLVLIRLKKKGDR 509
+ VVLG + Q+F +EK Y+ Y+ + H D+ L++LK
Sbjct: 366 IKTRH--LKVVLGDQDLKKEEFHEQSFRVEKIFKYSHYNERDEIPHNDIALLKLKPVDGH 423
Query: 510 CATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSS 569
CA S++V+ +CLP+ +FP+G +C I+GWG + E G S L +A V L+A+ C+S
Sbjct: 424 CALESKYVKTVCLPD--GSFPSGSECHISGWG-VTETGKG-SRQLLDAKVKLIANTLCNS 479
Query: 570 PEVYGADISPNMLCAGYFDCK-SDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKP 628
++Y I +M+CAG D CQGDSGGPL CEK+G Y+YGI+SWG CG+ +P
Sbjct: 480 RQLYDHMIDDSMICAGNLQKPGQDTCQGDSGGPLTCEKDGTYYVYGIVSWGLECGK--RP 537
Query: 629 GVYTRVANYVDWINDRIR 646
GVYT+V +++WI I+
Sbjct: 538 GVYTQVTKFLNWIKATIK 555
Score = 44.7 bits (104), Expect = 3e-04
Identities = 37/133 (27%), Positives = 51/133 (38%), Gaps = 24/133 (18%)
Query: 102 TED-GRPCR-FPFRYGGRML-----HACTSEGSAHRKWCATTHNYDRDRAWG--YCVEAT 152
TED PC+ P +GG L C+ C N +D G C+
Sbjct: 70 TEDQADPCQPNPCEHGGDCLVHGSTFTCSCLAPFSGNKCQKVQNTCKDNPCGRGQCLITQ 129
Query: 153 PPP----------GGPAA---LDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDC-- 197
PP GP+ + C PC NG +CS + + C+CP F GK C
Sbjct: 130 SPPYYRCVCKHPYTGPSCSQVVPVCRPNPCQNGATCSRHKRRSKFTCACPDQFKGKFCEI 189
Query: 198 GTEKCFDETRYEY 210
G++ C+ Y Y
Sbjct: 190 GSDDCYVGDGYSY 202
>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
[Homo sapiens]
Length = 516
Score = 294 bits (753), Expect = 2e-79
Identities = 179/526 (34%), Positives = 259/526 (49%), Gaps = 77/526 (14%)
Query: 157 GPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEK---CFDETRYEYLEG 213
G + C+ C NGG+C + C CP F GK C + C+++ Y
Sbjct: 33 GARSYQGCSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYR-- 90
Query: 214 GDRWARVRQGHVEQCECFGGRTWCE----GTR----------HTACLSSPCLNGGTCHLI 259
W+ G +C + + G R H C + + C++
Sbjct: 91 -GTWSTAESG--AECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVF 147
Query: 260 VAT--GTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ 317
A + C+ P C+ E + C+ GNG+ YRG S + SG SCL WNS +L
Sbjct: 148 KAGKYSSEFCSTPA------CS-EGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIG 200
Query: 318 ELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLSP 377
+++ +A LGLG H YCRNPD D +PWC+V+K+ L+WEYC + +C +
Sbjct: 201 KVYTAQNPSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST-------- 252
Query: 378 DLLATLPEPASPGRQACG-RRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDS 430
CG R++ + F RI GG + SHPW AAI+ G+
Sbjct: 253 ----------------CGLRQYSQPQF---RIKGGLFADIASHPWQAAIFAKHRRSPGER 293
Query: 431 F-CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYS 489
F C G L+ +CW++SAAHCF P ++V+LG+ + + Q F +EKYI + +
Sbjct: 294 FLCGGILISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD 353
Query: 490 VFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSG 549
+ D+D+ L++LK RCA S V+ +CLP P +C+++G+G +
Sbjct: 354 -DDTYDNDIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPF 412
Query: 550 YSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGGP 601
YS L+EA V L +C+S + ++ NMLCAG D +S DACQGDSGGP
Sbjct: 413 YSERLKEAHVRLYPSSRCTSQHLLNRTVTDNMLCAG--DTRSGGPQANLHDACQGDSGGP 470
Query: 602 LACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRP 647
L C +G L GIISWG GCG+ PGVYT+V NY+DWI D +RP
Sbjct: 471 LVCLNDGRMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP 516
>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
[Homo sapiens]
Length = 562
Score = 293 bits (751), Expect = 3e-79
Identities = 178/519 (34%), Positives = 257/519 (49%), Gaps = 77/519 (14%)
Query: 164 CASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEK---CFDETRYEYLEGGDRWARV 220
C+ C NGG+C + C CP F GK C + C+++ Y W+
Sbjct: 86 CSEPRCFNGGTCQQALYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYR---GTWSTA 142
Query: 221 RQGHVEQCECFGGRTWCE----GTR----------HTACLSSPCLNGGTCHLIVAT--GT 264
G +C + + G R H C + + C++ A +
Sbjct: 143 ESG--AECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSS 200
Query: 265 TVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSV 324
C+ P C+ E + C+ GNG+ YRG S + SG SCL WNS +L +++
Sbjct: 201 EFCSTPA------CS-EGNSDCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQN 253
Query: 325 GAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLP 384
+A LGLG H YCRNPD D +PWC+V+K+ L+WEYC + +C +
Sbjct: 254 PSAQALGLGKHNYCRNPDGDAKPWCHVLKNRRLTWEYCDVPSCST--------------- 298
Query: 385 EPASPGRQACG-RRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI------GDSF-CAGSL 436
CG R++ + F RI GG + SHPW AAI+ G+ F C G L
Sbjct: 299 ---------CGLRQYSQPQF---RIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGIL 346
Query: 437 VHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH 496
+ +CW++SAAHCF P ++V+LG+ + + Q F +EKYI + + + D+
Sbjct: 347 ISSCWILSAAHCFQERFPPHHLTVILGRTYRVVPGEEEQKFEVEKYIVHKEFD-DDTYDN 405
Query: 497 DLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLRE 556
D+ L++LK RCA S V+ +CLP P +C+++G+G + YS L+E
Sbjct: 406 DIALLQLKSDSSRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKE 465
Query: 557 ALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKS--------DACQGDSGGPLACEKNG 608
A V L +C+S + ++ NMLCAG D +S DACQGDSGGPL C +G
Sbjct: 466 AHVRLYPSSRCTSQHLLNRTVTDNMLCAG--DTRSGGPQANLHDACQGDSGGPLVCLNDG 523
Query: 609 VAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIRP 647
L GIISWG GCG+ PGVYT+V NY+DWI D +RP
Sbjct: 524 RMTLVGIISWGLGCGQKDVPGVYTKVTNYLDWIRDNMRP 562
Score = 139 bits (351), Expect = 6e-33
Identities = 69/168 (41%), Positives = 81/168 (48%), Gaps = 2/168 (1%)
Query: 202 CFDETRYEYLEGGDRWAR--VRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLI 259
C DE + W R +R VE C C GR C +C C NGGTC
Sbjct: 41 CRDEKTQMIYQQHQSWLRPVLRSNRVEYCWCNSGRAQCHSVPVKSCSEPRCFNGGTCQQA 100
Query: 260 VATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQEL 319
+ VC CP GFAG+ C I+ C+ G YRG ST+ SG C WNS L Q+
Sbjct: 101 LYFSDFVCQCPEGFAGKCCEIDTRATCYEDQGISYRGTWSTAESGAECTNWNSSALAQKP 160
Query: 320 HVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEAC 367
+ A LGLG H YCRNPD D +PWCYV K S E+C AC
Sbjct: 161 YSGRRPDAIRLGLGNHNYCRNPDRDSKPWCYVFKAGKYSSEFCSTPAC 208
>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
[Homo sapiens]
Length = 431
Score = 277 bits (709), Expect = 2e-74
Identities = 159/418 (38%), Positives = 213/418 (50%), Gaps = 31/418 (7%)
Query: 242 HTACLSSPCLNGGTC-HLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVAST 300
H + CLNGGTC + C CP F G+ C I+ + C+ GNG YRG AST
Sbjct: 25 HQVPSNCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKAST 84
Query: 301 SASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWE 360
G CL WNS + Q+ + A LGLG H YCRNPDN RPWCYV +
Sbjct: 85 DTMGRPCLPWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQ 144
Query: 361 YCRLEACESLTRVQLSPDLLATLPEPASPGRQA---CGRRHKKRTFLRPR--IIGGSSSL 415
C + C A +P+SP + CG++ LRPR IIGG +
Sbjct: 145 ECMVHDC-------------ADGKKPSSPPEELKFQCGQKT-----LRPRFKIIGGEFTT 186
Query: 416 PGSHPWLAAIYI---GDSF---CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNR 469
+ PW AAIY G S C GSL+ CWV+SA HCF P ++ V LG+ N
Sbjct: 187 IENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNS 246
Query: 470 TTDVTQTFGIEKYIPYTLYSVFNPSDH-DLVLIRLKKKGDRCATRSQFVQPICLPEPGST 528
T F +E I + YS + H D+ L++++ K RCA S+ +Q ICLP +
Sbjct: 247 NTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYND 306
Query: 529 FPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFD 588
G C+I G+G + Y L+ +V L++ +C P YG++++ MLCA
Sbjct: 307 PQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQ 366
Query: 589 CKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
K+D+CQGDSGGPL C G L GI+SWG GC KPGVYTRV++++ WI +
Sbjct: 367 WKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 424
Score = 36.6 bits (83), Expect = 0.075
Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 3/42 (7%)
Query: 169 CLNGGSC-SNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYE 209
CLNGG+C SN + C+CP+ F G+ C +K +T YE
Sbjct: 33 CLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDK--SKTCYE 72
>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
sapiens]
Length = 414
Score = 277 bits (708), Expect = 3e-74
Identities = 158/410 (38%), Positives = 211/410 (51%), Gaps = 31/410 (7%)
Query: 250 CLNGGTC-HLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCL 308
CLNGGTC + C CP F G+ C I+ + C+ GNG YRG AST G CL
Sbjct: 16 CLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDKSKTCYEGNGHFYRGKASTDTMGRPCL 75
Query: 309 AWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACE 368
WNS + Q+ + A LGLG H YCRNPDN RPWCYV + C + C
Sbjct: 76 PWNSATVLQQTYHAHRSDALQLGLGKHNYCRNPDNRRRPWCYVQVGLKPLVQECMVHDC- 134
Query: 369 SLTRVQLSPDLLATLPEPASPGRQA---CGRRHKKRTFLRPR--IIGGSSSLPGSHPWLA 423
A +P+SP + CG++ LRPR IIGG + + PW A
Sbjct: 135 ------------ADGKKPSSPPEELKFQCGQKT-----LRPRFKIIGGEFTTIENQPWFA 177
Query: 424 AIYI---GDSF---CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTF 477
AIY G S C GSL+ CWV+SA HCF P ++ V LG+ N T F
Sbjct: 178 AIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKF 237
Query: 478 GIEKYIPYTLYSVFNPSDH-DLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQ 536
+E I + YS + H D+ L++++ K RCA S+ +Q ICLP + G C+
Sbjct: 238 EVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTICLPSMYNDPQFGTSCE 297
Query: 537 IAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQG 596
I G+G + Y L+ +V L++ +C P YG++++ MLCA K+D+CQG
Sbjct: 298 ITGFGKENSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQG 357
Query: 597 DSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
DSGGPL C G L GI+SWG GC KPGVYTRV++++ WI +
Sbjct: 358 DSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK 407
Score = 37.0 bits (84), Expect = 0.057
Identities = 19/46 (41%), Positives = 27/46 (58%), Gaps = 3/46 (6%)
Query: 165 ASGPCLNGGSC-SNTQDPQSYHCSCPRAFTGKDCGTEKCFDETRYE 209
A+ CLNGG+C SN + C+CP+ F G+ C +K +T YE
Sbjct: 12 ANCDCLNGGTCVSNKYFSNIHWCNCPKKFGGQHCEIDK--SKTCYE 55
>gi|4505881 plasminogen [Homo sapiens]
Length = 810
Score = 208 bits (530), Expect = 1e-53
Identities = 165/577 (28%), Positives = 237/577 (41%), Gaps = 90/577 (15%)
Query: 92 SSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC--- 148
S+ +P T + PC+ + C + WC TT++ R W YC
Sbjct: 300 SAQTPHTHNRTPENFPCK------NLDENYCRNPDGKRAPWCHTTNSQVR---WEYCKIP 350
Query: 149 -VEATP------PPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCGTEK 201
+++P P P L P C +G D QSY + TGK C +
Sbjct: 351 SCDSSPVSTEQLAPTAPPELTPVVQD-CYHG-------DGQSYRGTSSTTTTGKKCQSWS 402
Query: 202 CFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCHLIVA 261
R++ A + + + G WC T P + C+L
Sbjct: 403 SMTPHRHQKTPENYPNAGLTMNYCRNPDADKG-PWCFTT-------DPSVRWEYCNLKKC 454
Query: 262 TGTTVCACPPGFAGRLCNIEP--DERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQEL 319
+GT P L ++E +E C GNG GYRG +T+ +G C W + QE
Sbjct: 455 SGTEASVVAPPPVVLLPDVETPSEEDCMFGNGKGYRGKRATTVTGTPCQDWAA----QEP 510
Query: 320 HVDSVGAAALLGLGPHA-----YCRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRV 373
H S+ P A YCRNPD D PWCY L ++YC + C
Sbjct: 511 HRHSIFTPET---NPRAGLEKNYCRNPDGDVGGPWCYTTNPRKL-YDYCDVPQC------ 560
Query: 374 QLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGDSF 431
A+P CG+ + R++GG + P S PW ++ G F
Sbjct: 561 -------------AAPSFD-CGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHF 606
Query: 432 CAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYS-- 489
C G+L+ WV++AAHC SP S V+LG H Q +E ++ S
Sbjct: 607 CGGTLISPEWVLTAAHCLEKSPRPSSYKVILGAH---------QEVNLEPHVQEIEVSRL 657
Query: 490 VFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSG 549
P+ D+ L++L A + V P CLP P +C I GWG
Sbjct: 658 FLEPTRKDIALLKLSSP----AVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG- 712
Query: 550 YSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGV 609
+ L+EA +P++ + C+ E + LCAG+ +D+CQGDSGGPL C +
Sbjct: 713 -AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDK 771
Query: 610 AYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
L G+ SWG GC R +KPGVY RV+ +V WI +R
Sbjct: 772 YILQGVTSWGLGCARPNKPGVYVRVSRFVTWIEGVMR 808
Score = 67.4 bits (163), Expect = 4e-11
Identities = 40/130 (30%), Positives = 59/130 (45%), Gaps = 16/130 (12%)
Query: 267 CACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGA 326
C PP +G P +C G G YRG + + SG +C W++ +
Sbjct: 262 CTTPPPSSG------PTYQCLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFP 315
Query: 327 AALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACES--LTRVQLSPDLLATLP 384
L YCRNPD PWC+ +S + WEYC++ +C+S ++ QL+P T P
Sbjct: 316 CKNL---DENYCRNPDGKRAPWCHTT-NSQVRWEYCKIPSCDSSPVSTEQLAP----TAP 367
Query: 385 EPASPGRQAC 394
+P Q C
Sbjct: 368 PELTPVVQDC 377
Score = 58.2 bits (139), Expect = 2e-08
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Query: 280 IEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCR 339
+E +E C +G Y G S + SGL C AW+S + ++ S L YCR
Sbjct: 179 LECEEECMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKN---YCR 235
Query: 340 NPDNDERPWCYVVKDSALSWEYCRLEAC 367
NPD + RPWC+ D WE C + C
Sbjct: 236 NPDRELRPWCFTT-DPNKRWELCDIPRC 262
Score = 57.8 bits (138), Expect = 3e-08
Identities = 30/84 (35%), Positives = 43/84 (51%), Gaps = 5/84 (5%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDND- 344
C GNG YRG S + +G++C W+S ++ + + L YCRNPDND
Sbjct: 103 CKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGL---EENYCRNPDNDP 159
Query: 345 ERPWCYVVKDSALSWEYCRLEACE 368
+ PWCY D ++YC + CE
Sbjct: 160 QGPWCYTT-DPEKRYDYCDILECE 182
>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
Length = 2040
Score = 185 bits (470), Expect = 1e-46
Identities = 168/639 (26%), Positives = 247/639 (38%), Gaps = 101/639 (15%)
Query: 48 NATATPAIPT-ILVTSVTSETPATSAPEAEGP-QSGGLPPPPRAVPSSSSPQAQALTEDG 105
N T P + +L T + P+T AP + P + + S + T G
Sbjct: 1461 NLTRCPVTESSVLTTPTVAPVPSTEAPSEQAPPEKSPVVQDCYHGDGRSYRGISSTTVTG 1520
Query: 106 RPC------------RFPFRY--GGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC--V 149
R C R P Y G + C + S + WC TT R W YC
Sbjct: 1521 RTCQSWSSMIPHWHQRTPENYPNAGLTENYCRNPDSGKQPWCYTTDPCVR---WEYCNLT 1577
Query: 150 EATPPPGGPAALDPCASGPCLNGGS--CSNTQDP----------QSYHCSCPRAFTGKDC 197
+ + G P + S Q P QSY + TG+ C
Sbjct: 1578 QCSETESGVLETPTVVPVPSMEAHSEAAPTEQTPVVRQCYHGNGQSYRGTFSTTVTGRTC 1637
Query: 198 GTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGGTCH 257
+ R++ + + + G WC P + C+
Sbjct: 1638 QSWSSMTPHRHQRTPENYPNDGLTMNYCRNPDADTG-PWC-------FTMDPSIRWEYCN 1689
Query: 258 LIVATGTTVCACPPGFAGRLCNIEP--DERCFLGNGTGYRGVASTSASGLSCLAWNSDLL 315
L + T P ++ ++ P ++ C GNG GYRG +T+ +G C W +
Sbjct: 1690 LTRCSDTEGTVVAPPTVIQVPSLGPPSEQDCMFGNGKGYRGKKATTVTGTPCQEWAA--- 1746
Query: 316 YQELHVDSV---GAAALLGLGPHAYCRNPDND-ERPWCYVVKDSALSWEYCRLEACESLT 371
QE H S G GL + YCRNPD D PWCY + L ++YC + C S +
Sbjct: 1747 -QEPHRHSTFIPGTNKWAGLEKN-YCRNPDGDINGPWCYTMNPRKL-FDYCDIPLCASSS 1803
Query: 372 RVQLSPDLLATLPEPASPGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIY--IGD 429
CG+ + I+GG + P S PW ++ G
Sbjct: 1804 F--------------------DCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGK 1843
Query: 430 SFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYS 489
FC G+L+ WV++AAHC S S V+LG H Q +E ++ S
Sbjct: 1844 HFCGGTLISPEWVLTAAHCLKKSSRPSSYKVILGAH---------QEVNLESHVQEIEVS 1894
Query: 490 --VFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENV 547
P+ D+ L++L R A + V P CLP P A +C I GWG
Sbjct: 1895 RLFLEPTQADIALLKLS----RPAVITDKVMPACLPSPDYMVTARTECYITGWGETQGTF 1950
Query: 548 SGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKN 607
+ L+EA + ++ + C+ + +CA + +D+CQGDSGGPL C +
Sbjct: 1951 G--TGLLKEAQLLVIENEVCNHYKY---------ICAEHLARGTDSCQGDSGGPLVCFEK 1999
Query: 608 GVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
L G+ SWG GC R +KPGVY RV+ +V WI +R
Sbjct: 2000 DKYILQGVTSWGLGCARPNKPGVYARVSRFVTWIEGMMR 2038
Score = 82.4 bits (202), Expect = 1e-15
Identities = 91/377 (24%), Positives = 131/377 (34%), Gaps = 57/377 (15%)
Query: 47 PNATATPAIPTILVTSVTSETPATS------APEAEGPQSGGLPPPPRAVPSSSSPQAQA 100
PN P++ ++T ETP G S + SS +P +
Sbjct: 1028 PNVILAPSLEAFFEQALTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHS 1087
Query: 101 LTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYC------------ 148
T + P G + C + + R WC T D W YC
Sbjct: 1088 RTPENYP------NAGLTRNYCRNPDAEIRPWCYTM---DPSVRWEYCNLTQCLVTESSV 1138
Query: 149 ---VEATPPPGGPAALDPCASGPCLNGGSCSNTQDPQSYHCSCPRAFTGKDCG-----TE 200
+ P P A+ + + C + D QSY S TG+ C T
Sbjct: 1139 LATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG-DGQSYRGSFSTTVTGRTCQSWSSMTP 1197
Query: 201 KCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWC----EGTRHTACLSSPCLNGGTC 256
T Y GG R E WC R C + C T
Sbjct: 1198 HWHQRTTEYYPNGGLTRNYCRNPDAEISP------WCYTMDPNVRWEYCNLTQC--PVTE 1249
Query: 257 HLIVATGTTVCACPPGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLY 316
++AT T V P + C+ G+G YRG ST+ +G +C +W+S +
Sbjct: 1250 SSVLATSTAVSEQAPTEQSPTV-----QDCYHGDGQSYRGSFSTTVTGRTCQSWSS--MT 1302
Query: 317 QELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQLS 376
H + GL + YCRNPD + RPWCY + D ++ WEYC L C + L+
Sbjct: 1303 PHWHQRTTEYYPNGGLTRN-YCRNPDAEIRPWCYTM-DPSVRWEYCNLTQCPVMESTLLT 1360
Query: 377 PDLLATLPEPASPGRQA 393
+ +P P +A
Sbjct: 1361 TPTVVPVPSTELPSEEA 1377
Score = 80.1 bits (196), Expect = 6e-15
Identities = 96/379 (25%), Positives = 131/379 (34%), Gaps = 66/379 (17%)
Query: 57 TILVTSVTSETPATSAPEAEGP--QSGGLPPPPRAVPSSSSPQAQALTEDGRPCRF---- 110
++L T P+T A E P QS G+ S + + T GR C+
Sbjct: 1137 SVLATLTVVPDPSTEASSEEAPTEQSPGVQDCYHG-DGQSYRGSFSTTVTGRTCQSWSSM 1195
Query: 111 ----------PFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRAWGYCVEATPPPGGPAA 160
+ GG + C + + WC T D + W YC P +
Sbjct: 1196 TPHWHQRTTEYYPNGGLTRNYCRNPDAEISPWCYTM---DPNVRWEYCNLTQCPVTESSV 1252
Query: 161 LD---------PCASGP----CLNGGSCSNTQDPQSYHCSCPRAFTGKDCG-----TEKC 202
L P P C +G D QSY S TG+ C T
Sbjct: 1253 LATSTAVSEQAPTEQSPTVQDCYHG-------DGQSYRGSFSTTVTGRTCQSWSSMTPHW 1305
Query: 203 FDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWC----EGTRHTACLSSPCLNGGTCHL 258
T Y GG R E R WC R C + C
Sbjct: 1306 HQRTTEYYPNGGLTRNYCRNPDAEI------RPWCYTMDPSVRWEYCNLTQC---PVMES 1356
Query: 259 IVATGTTVCACP----PGFAGRLCNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDL 314
+ T TV P P N + C+ G+G YRG ST+ +G +C +W+S
Sbjct: 1357 TLLTTPTVVPVPSTELPSEEAPTENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMT 1416
Query: 315 LYQELHVDSVGAAALLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACESLTRVQ 374
+ + A L YCRNPD + RPWCY + D ++ WEYC L C
Sbjct: 1417 PHWHRRIPLYYPNAGL---TRNYCRNPDAEIRPWCYTM-DPSVRWEYCNLTRCPVTESSV 1472
Query: 375 LSPDLLATLPEPASPGRQA 393
L+ +A +P +P QA
Sbjct: 1473 LTTPTVAPVPSTEAPSEQA 1491
Score = 74.7 bits (182), Expect = 2e-13
Identities = 37/110 (33%), Positives = 54/110 (49%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 824 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDP 880
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D ++ WEYC L C ++P + +P +P QA
Sbjct: 881 VAAPYCY-TRDPSVRWEYCNLTQCSDAEGTAVAPPTITPIPSLEAPSEQA 929
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 140 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 196
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 197 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 245
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 254 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 310
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 311 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 359
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 368 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 424
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 425 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 473
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 482 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 538
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 539 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 587
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 596 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 652
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 653 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 701
Score = 73.6 bits (179), Expect = 6e-13
Identities = 37/110 (33%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG YRG ST+ +G +C AW+S + A L + YCRNPD
Sbjct: 710 QECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMN---YCRNPDA 766
Query: 344 DERPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 767 VAAPYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 815
Score = 71.6 bits (174), Expect = 2e-12
Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 4/108 (3%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
C+ G+G YRG ST+ +G +C AW+S +Q A L + YCRNPD
Sbjct: 28 CYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMN---YCRNPDAVA 84
Query: 346 RPWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQA 393
P+CY +D + WEYC L C ++P + +P +P QA
Sbjct: 85 APYCY-TRDPGVRWEYCNLTQCSDAEGTAVAPPTVTPVPSLEAPSEQA 131
Score = 62.8 bits (151), Expect = 1e-09
Identities = 40/121 (33%), Positives = 55/121 (45%), Gaps = 14/121 (11%)
Query: 284 ERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDN 343
+ C+ GNG Y+G + +G +C AW+S + H + GL + YCRNPD
Sbjct: 938 QECYHGNGQSYQGTYFITVTGRTCQAWSS--MTPHSHSRTPAYYPNAGLIKN-YCRNPDP 994
Query: 344 DERPWCYVVKDSALSWEYCRLEACESL-------TRVQLSPDLLATLPE---PASPGRQA 393
PWCY D ++ WEYC L C V L+P L A + +PG Q
Sbjct: 995 VAAPWCYTT-DPSVRWEYCNLTRCSDAEWTAFVPPNVILAPSLEAFFEQALTEETPGVQD 1053
Query: 394 C 394
C
Sbjct: 1054 C 1054
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 185 bits (469), Expect = 1e-46
Identities = 100/258 (38%), Positives = 147/258 (56%), Gaps = 17/258 (6%)
Query: 407 RIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 465
RI GGSS++ G PW +I Y G C GSLV WV+SAAHCF +++ V LG H
Sbjct: 44 RITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAH 103
Query: 466 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 525
+ ++ + ++ IP+ Y + S D+ L++L R T S++++PICLP
Sbjct: 104 QLDSYSEDAKVSTLKDIIPHPSY-LQEGSQGDIALLQLS----RPITFSRYIRPICLPAA 158
Query: 526 GSTFPAGHKCQIAGWGHLDENVSGYSSS-LREALVPLVADHKCSSPEVYGADISP----- 579
++FP G C + GWGH+ +VS + L++ VPL++ C+ +Y D P
Sbjct: 159 NASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNC--LYNIDAKPEEPHF 216
Query: 580 ---NMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVAN 636
+M+CAGY + DACQGDSGGPL+C G+ YL GI+SWGD CG ++PGVYT ++
Sbjct: 217 VQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASS 276
Query: 637 YVDWINDRIRPPRRLVAP 654
Y WI ++ + V P
Sbjct: 277 YASWIQSKVTELQPRVVP 294
>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
Length = 457
Score = 180 bits (457), Expect = 3e-45
Identities = 109/284 (38%), Positives = 146/284 (51%), Gaps = 24/284 (8%)
Query: 374 QLSPDLLATLPEPASPGRQA------------CGRRHKKRTFLRPRIIGGSSSLPGSHPW 421
QLSP L L E P CG R L RI+GG S PG PW
Sbjct: 177 QLSPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARP-----LASRIVGGQSVAPGRWPW 231
Query: 422 LAAIYIGDSF-CAGSLVHTCWVVSAAHCF-SHSPPRDSVSVVLGQHFFNRTTDVTQTFGI 479
A++ +G C GS++ WVV+AAHC S R S V + Q +
Sbjct: 232 QASVALGFRHTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGALV 291
Query: 480 EKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAG 539
E+ IP+ LYS N D+D+ L+RL+ S V +CLP FP G +C ++G
Sbjct: 292 ERIIPHPLYSAQN-HDYDVALLRLQT----ALNFSDTVGAVCLPAKEQHFPKGSRCWVSG 346
Query: 540 WGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSG 599
WGH + + S L++ +VPL + C+S VY ++P MLCAGY D ++DACQGDSG
Sbjct: 347 WGHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSG 406
Query: 600 GPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 643
GPL C L G++SWG GC + PGVY +VA ++DWI+D
Sbjct: 407 GPLVCPDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWIHD 450
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 167 bits (424), Expect = 2e-41
Identities = 90/254 (35%), Positives = 142/254 (55%), Gaps = 12/254 (4%)
Query: 393 ACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSH 451
ACG R + RI+GG+ SL PW A++ + G C GS++ W+++AAHC
Sbjct: 206 ACGHRRGYSS----RIVGGNMSLLSQWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYD 261
Query: 452 SPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCA 511
S ++ +G + + + +EK + ++ Y +D+ L++L
Sbjct: 262 LYLPKSWTIQVG--LVSLLDNPAPSHLVEKIVYHSKYKP-KRLGNDIALMKLAGP----L 314
Query: 512 TRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPE 571
T ++ +QP+CLP FP G C +GWG ++ S L A VPL+++ C+ +
Sbjct: 315 TFNEMIQPVCLPNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRD 374
Query: 572 VYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVY 631
VYG ISP+MLCAGY D+CQGDSGGPL C++ + L G S+G GC ++KPGVY
Sbjct: 375 VYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVY 434
Query: 632 TRVANYVDWINDRI 645
TRV +++DWI++++
Sbjct: 435 TRVTSFLDWIHEQM 448
>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
Length = 1059
Score = 165 bits (417), Expect = 1e-40
Identities = 88/251 (35%), Positives = 136/251 (54%), Gaps = 9/251 (3%)
Query: 407 RIIGGSSSLPGSHPWLAAIYIG-DSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 465
RI+GG + PG PW A++ + FC ++++ W+VSAAHCF+ +G
Sbjct: 202 RIVGGMEASPGEFPWQASLRENKEHFCGAAIINARWLVSAAHCFNEFQDPTKWVAYVGAT 261
Query: 466 FFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEP 525
+ + + T + + + + LY+ + +D D+ ++ L + +QP+CLP
Sbjct: 262 YLSGSEASTVRAQVVQIVKHPLYNA-DTADFDVAVLELTSP----LPFGRHIQPVCLPAA 316
Query: 526 GSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAG 585
FP KC I+GWG+L E+ L++A V L+ C+S +YG ++ M+CAG
Sbjct: 317 THIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS--LYGHSLTDRMVCAG 374
Query: 586 YFDCKSDACQGDSGGPLACEK-NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDR 644
Y D K D+CQGDSGGPL CE+ +G +L GI+SWG GC +PGVY RV DWI +
Sbjct: 375 YLDGKVDSCQGDSGGPLVCEEPSGRFFLAGIVSWGIGCAEARRPGVYARVTRLRDWILEA 434
Query: 645 IRPPRRLVAPS 655
+AP+
Sbjct: 435 TTKASMPLAPT 445
Score = 164 bits (414), Expect = 3e-40
Identities = 94/257 (36%), Positives = 136/257 (52%), Gaps = 16/257 (6%)
Query: 389 PGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAH 447
P Q CG R R++GG + G PW ++ G FC ++V W++SAAH
Sbjct: 487 PKLQECGARPAMEK--PTRVVGGFGAASGEVPWQVSLKEGSRHFCGATVVGDRWLLSAAH 544
Query: 448 CFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPS--DHDLVLIRLKK 505
CF+H+ + V LG G+ + + + LY NP D DL ++ L
Sbjct: 545 CFNHTKV-EQVRAHLGTASLLGLGGSPVKIGLRRVVLHPLY---NPGILDFDLAVLELAS 600
Query: 506 KGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADH 565
++++QP+CLP FP G KC I+GWG+ E + L++A V ++
Sbjct: 601 P----LAFNKYIQPVCLPLAIQKFPVGRKCMISGWGNTQEGNATKPELLQKASVGIIDQK 656
Query: 566 KCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKN-GVAYLYGIISWGDGCGR 624
CS +Y ++ M+CAG+ + K D+CQGDSGGPLACE+ GV YL GI+SWG GC +
Sbjct: 657 TCSV--LYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACEEAPGVFYLAGIVSWGIGCAQ 714
Query: 625 LHKPGVYTRVANYVDWI 641
+ KPGVYTR+ WI
Sbjct: 715 VKKPGVYTRITRLKGWI 731
Score = 152 bits (385), Expect = 7e-37
Identities = 95/244 (38%), Positives = 131/244 (53%), Gaps = 15/244 (6%)
Query: 407 RIIGGSSSLPGSHPWLAAIYIG--DSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQ 464
RI+GGS++ G PW ++++ + C LV W++SAAHCF + LG
Sbjct: 826 RIVGGSAAGRGEWPWQVSLWLRRREHRCGAVLVAERWLLSAAHCFDVYGDPKQWAAFLGT 885
Query: 465 HFFNRTT-DVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 523
F + + + I K+ Y LY++ D+D+ L+ L RS+ V+PICLP
Sbjct: 886 PFLSGAEGQLERVARIYKHPFYNLYTL----DYDVALLELAGP----VRRSRLVRPICLP 937
Query: 524 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 583
EP P G +C I GWG + E S + L++A V L+++ C Y IS MLC
Sbjct: 938 EPAPRPPDGTRCVITGWGSVREGGS-MARQLQKAAVRLLSEQTCR--RFYPVQISSRMLC 994
Query: 584 AGYFDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIN 642
AG+ D+C GD+GGPLAC E +G L G+ SWG GCGR H PGVYTRVA WI
Sbjct: 995 AGFPQGGVDSCSGDAGGPLACREPSGRWVLTGVTSWGYGCGRPHFPGVYTRVAAVRGWIG 1054
Query: 643 DRIR 646
I+
Sbjct: 1055 QHIQ 1058
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 163 bits (412), Expect = 5e-40
Identities = 102/294 (34%), Positives = 153/294 (52%), Gaps = 16/294 (5%)
Query: 360 EYCRLEACESLTRVQL--SPDLLATLPEPASP-GRQAC--GRRHKKRTFLRPRIIGGSSS 414
E C+ E C+ R+ + SP +A + +S + C G T RI+GG++S
Sbjct: 338 EDCKEEKCKCFLRLSMDGSPTRIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNS 397
Query: 415 LPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRT 470
G PW ++ + + C GSL+ WV++AAHCF P +D + G +
Sbjct: 398 SWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDI 457
Query: 471 TDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFP 530
T T I++ I + Y V + +HD+ LI+L+ ++F +PICLP G T
Sbjct: 458 TKDTPFSQIKEIIIHQNYKV-SEGNHDIALIKLQAP----LNYTEFQKPICLPSKGDTST 512
Query: 531 AGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDCK 590
C + GWG E + L++ +PLV + +C I+ M+CAGY +
Sbjct: 513 IYTNCWVTGWGFSKEK-GEIQNILQKVNIPLVTNEECQK-RYQDYKITQRMVCAGYKEGG 570
Query: 591 SDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDR 644
DAC+GDSGGPL C+ NG+ L GI SWG+GC R +PGVYT+VA Y+DWI ++
Sbjct: 571 KDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWILEK 624
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 162 bits (410), Expect = 9e-40
Identities = 101/268 (37%), Positives = 141/268 (52%), Gaps = 18/268 (6%)
Query: 384 PEPASPGRQAC----GRRHKKRTFLRP--RIIGGSSSLPGSHPWLAAIYI-GDSFCAGSL 436
P P GR C H P RI+GG+ S G PW A++ + G C G+L
Sbjct: 547 PNPQCDGRPDCRDGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGAL 606
Query: 437 VHTCWVVSAAHCFSHSPPRDSV--SVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPS 494
+ WV++AAHCF +V +V LG+ + N +F + + + + Y +
Sbjct: 607 IADRWVITAAHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHP-YHEEDSH 665
Query: 495 DHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSL 554
D+D+ L++L D RS V+P+CLP F G C I GWG L E S++L
Sbjct: 666 DYDVALLQL----DHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREG-GPISNAL 720
Query: 555 REALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEK-NGVAYLY 613
++ V L+ CS EVY ++P MLCAGY K DACQGDSGGPL C+ +G +L
Sbjct: 721 QKVDVQLIPQDLCS--EVYRYQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLA 778
Query: 614 GIISWGDGCGRLHKPGVYTRVANYVDWI 641
G++SWG GCGR + GVYTR+ + WI
Sbjct: 779 GLVSWGLGCGRPNYFGVYTRITGVISWI 806
>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
sapiens]
Length = 723
Score = 160 bits (406), Expect = 3e-39
Identities = 110/368 (29%), Positives = 165/368 (44%), Gaps = 36/368 (9%)
Query: 278 CNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAY 337
C++ + C+ GNG Y G S + SGL+C W+ ++ H+ A+ L Y
Sbjct: 378 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN---ENY 434
Query: 338 CRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGR 396
CRNPD+D PWCY + + W+YC + CE T + L P +C +
Sbjct: 435 CRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTT-----PTIVNLDHPVI----SCAK 484
Query: 397 RHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRD 456
+ R ++ G + ++ Y C GSL+ WV++A CF P RD
Sbjct: 485 TKQLR------VVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCF---PSRD 535
Query: 457 --SVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRS 514
LG H + D K + V+ P DLVL++L R A
Sbjct: 536 LKDYEAWLGIHDVHGRGDEKC-----KQVLNVSQLVYGPEGSDLVLMKLA----RPAVLD 586
Query: 515 QFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYG 574
FV I LP G T P C + GWG+ + Y LR A + ++ + KCS
Sbjct: 587 DFVSTIDLPNYGCTIPEKTSCSVYGWGYT--GLINYDGLLRVAHLYIMGNEKCSQHHRGK 644
Query: 575 ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRV 634
++ + +CAG S C+GD GGPL CE++ + + G+I G GC ++PG++ RV
Sbjct: 645 VTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRV 704
Query: 635 ANYVDWIN 642
A Y WI+
Sbjct: 705 AYYAKWIH 712
Score = 56.6 bits (135), Expect = 7e-08
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLG-PHAYCRNPDND 344
C NG YRG+ + SG C W+ +Q H G YCRNPD
Sbjct: 206 CMTCNGESYRGLMDHTESGKICQRWD----HQTPHRHKFLPERYPDKGFDDNYCRNPDGQ 261
Query: 345 ERPWCYVVKDSALSWEYCRLEACESLT 371
RPWCY + D WEYC ++ C T
Sbjct: 262 PRPWCYTL-DPHTRWEYCAIKTCADNT 287
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ-ELHVDSVGAAALLGLGPHAYCRNPDND 344
C G G GYRG +T +G+ C W+S ++ ++ ++ L YCRNPD
Sbjct: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLR----ENYCRNPDGS 355
Query: 345 ERPWCYVVKDSALSWEYC 362
E PWC+ D + YC
Sbjct: 356 ESPWCFTT-DPNIRVGYC 372
Score = 46.6 bits (109), Expect = 7e-05
Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
C +G G Y+G S + SG+ C W+S + H S L YCRNP +E
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMI----PHEHSYRGKDL----QENYCRNPRGEE 179
Query: 346 -RPWCYVVKDSALSWEYCRLEACESL 370
PWC+ + + +E C + C +
Sbjct: 180 GGPWCF-TSNPEVRYEVCDIPQCSEV 204
>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
sapiens]
Length = 728
Score = 160 bits (406), Expect = 3e-39
Identities = 110/368 (29%), Positives = 165/368 (44%), Gaps = 36/368 (9%)
Query: 278 CNIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAY 337
C++ + C+ GNG Y G S + SGL+C W+ ++ H+ A+ L Y
Sbjct: 383 CDMSHGQDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLN---ENY 439
Query: 338 CRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLATLPEPASPGRQACGR 396
CRNPD+D PWCY + + W+YC + CE T + L P +C +
Sbjct: 440 CRNPDDDAHGPWCYT-GNPLIPWDYCPISRCEGDTT-----PTIVNLDHPVI----SCAK 489
Query: 397 RHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSFCAGSLVHTCWVVSAAHCFSHSPPRD 456
+ R ++ G + ++ Y C GSL+ WV++A CF P RD
Sbjct: 490 TKQLR------VVNGIPTRTNIGWMVSLRYRNKHICGGSLIKESWVLTARQCF---PSRD 540
Query: 457 --SVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRS 514
LG H + D K + V+ P DLVL++L R A
Sbjct: 541 LKDYEAWLGIHDVHGRGDEKC-----KQVLNVSQLVYGPEGSDLVLMKLA----RPAVLD 591
Query: 515 QFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYG 574
FV I LP G T P C + GWG+ + Y LR A + ++ + KCS
Sbjct: 592 DFVSTIDLPNYGCTIPEKTSCSVYGWGYT--GLINYDGLLRVAHLYIMGNEKCSQHHRGK 649
Query: 575 ADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRV 634
++ + +CAG S C+GD GGPL CE++ + + G+I G GC ++PG++ RV
Sbjct: 650 VTLNESEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRV 709
Query: 635 ANYVDWIN 642
A Y WI+
Sbjct: 710 AYYAKWIH 717
Score = 56.6 bits (135), Expect = 7e-08
Identities = 31/87 (35%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLG-PHAYCRNPDND 344
C NG YRG+ + SG C W+ +Q H G YCRNPD
Sbjct: 211 CMTCNGESYRGLMDHTESGKICQRWD----HQTPHRHKFLPERYPDKGFDDNYCRNPDGQ 266
Query: 345 ERPWCYVVKDSALSWEYCRLEACESLT 371
RPWCY + D WEYC ++ C T
Sbjct: 267 PRPWCYTL-DPHTRWEYCAIKTCADNT 292
Score = 50.8 bits (120), Expect = 4e-06
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ-ELHVDSVGAAALLGLGPHAYCRNPDND 344
C G G GYRG +T +G+ C W+S ++ ++ ++ L YCRNPD
Sbjct: 305 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLR----ENYCRNPDGS 360
Query: 345 ERPWCYVVKDSALSWEYC 362
E PWC+ D + YC
Sbjct: 361 ESPWCFTT-DPNIRVGYC 377
Score = 49.3 bits (116), Expect = 1e-05
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 5/86 (5%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
C +G G Y+G S + SG+ C W+S + ++ + S L YCRNP +E
Sbjct: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 184
Query: 346 -RPWCYVVKDSALSWEYCRLEACESL 370
PWC+ + + +E C + C +
Sbjct: 185 GGPWCF-TSNPEVRYEVCDIPQCSEV 209
>gi|223942069 enterokinase precursor [Homo sapiens]
Length = 1019
Score = 160 bits (406), Expect = 3e-39
Identities = 90/253 (35%), Positives = 148/253 (58%), Gaps = 11/253 (4%)
Query: 392 QACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDSF-CAGSLVHTCWVVSAAHC-F 449
++CG++ + + P+I+GGS++ G+ PW+ +Y G C SLV + W+VSAAHC +
Sbjct: 770 KSCGKKLAAQD-ITPKIVGGSNAKEGAWPWVVGLYYGGRLLCGASLVSSDWLVSAAHCVY 828
Query: 450 SHSPPRDSVSVVLGQHF-FNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGD 508
+ + +LG H N T+ T I++ + Y+ D+D+ ++ L+ K
Sbjct: 829 GRNLEPSKWTAILGLHMKSNLTSPQTVPRLIDEIVINPHYNR-RRKDNDIAMMHLEFK-- 885
Query: 509 RCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCS 568
+ ++QPICLPE FP G C IAGWG + + ++ L+EA VPL+++ +C
Sbjct: 886 --VNYTDYIQPICLPEENQVFPPGRNCSIAGWGTVVYQGTT-ANILQEADVPLLSNERCQ 942
Query: 569 SPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKP 628
++ +I+ NM+CAGY + D+CQGDSGGPL C++N +L G+ S+G C ++P
Sbjct: 943 Q-QMPEYNITENMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFGYKCALPNRP 1001
Query: 629 GVYTRVANYVDWI 641
GVY RV+ + +WI
Sbjct: 1002 GVYARVSRFTEWI 1014
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 160 bits (404), Expect = 5e-39
Identities = 90/257 (35%), Positives = 143/257 (55%), Gaps = 15/257 (5%)
Query: 394 CGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS----FCAGSLVHTCWVVSAAHCF 449
C ++ T ++PRI+GG++S+ G PW ++ C GS++ W+++AAHCF
Sbjct: 374 CKMDNECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCF 433
Query: 450 SHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDR 509
+ V G + + T FG+++ I + Y + S +D+ L++L+ +
Sbjct: 434 YGVESPKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKMAE-SGYDIALLKLETTVNY 492
Query: 510 CATRSQFVQPICLPEPGSTFPAGHKCQIAGWGH--LDENVSGYSSSLREALVPLVADHKC 567
T SQ +PICLP G C + GWG+ L + + ++L++A +PLV + +C
Sbjct: 493 --TDSQ--RPICLPSKGDRNVIYTDCWVTGWGYRKLRDKIQ---NTLQKAKIPLVTNEEC 545
Query: 568 SSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHK 627
G I+ M+CAGY + DAC+GDSGGPL+C+ N V +L GI SWG+GC + +
Sbjct: 546 QK-RYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRER 604
Query: 628 PGVYTRVANYVDWINDR 644
PGVYT V YVDWI ++
Sbjct: 605 PGVYTNVVEYVDWILEK 621
>gi|4506115 protein C [Homo sapiens]
Length = 461
Score = 157 bits (398), Expect = 2e-38
Identities = 107/322 (33%), Positives = 154/322 (47%), Gaps = 38/322 (11%)
Query: 361 YCRLEA----CESLTRVQLSPDLLATLPEPASPGRQACGRRHKKRTFLR----------- 405
YC E C +L DLL P P + R KKR+ L+
Sbjct: 150 YCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTEDQEDQVD 209
Query: 406 PRIIGGSSSLPGSHPWLAAIYIGDS--FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLG 463
PR+I G + G PW + C L+H WV++AAHC S + V LG
Sbjct: 210 PRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESK---KLLVRLG 266
Query: 464 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 523
++ R I++ + YS + +D+D+ L+ L + AT SQ + PICLP
Sbjct: 267 EYDLRRWEKWELDLDIKEVFVHPNYSK-STTDNDIALLHLAQP----ATLSQTIVPICLP 321
Query: 524 EPG----STFPAGHKCQIAGWGHLD----ENVSGYSSSLREALVPLVADHKCSSPEVYGA 575
+ G AG + + GWG+ E + L +P+V ++CS EV
Sbjct: 322 DSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECS--EVMSN 379
Query: 576 DISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVA 635
+S NMLCAG + DAC+GDSGGP+ +G +L G++SWG+GCG LH GVYT+V+
Sbjct: 380 MVSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGEGCGLLHNYGVYTKVS 439
Query: 636 NYVDWINDRIR---PPRRLVAP 654
Y+DWI+ IR P++ AP
Sbjct: 440 RYLDWIHGHIRDKEAPQKSWAP 461
Score = 30.0 bits (66), Expect = 7.0
Identities = 28/98 (28%), Positives = 36/98 (36%), Gaps = 10/98 (10%)
Query: 195 KDCGTEKCFDETRYEYLEGGDRWARVRQGHVEQCECFGGRTWCEGTRHTACLSSPCLNGG 254
++C E C E E + D HV+ +C H +S C G
Sbjct: 57 RECIEEICDFEEAKEIFQNVDDTLAFWSKHVDGDQCL-----VLPLEHPC--ASLCCGHG 109
Query: 255 TCHLIVATGTTVCACPPGFAGRLCNIEPD-ERCFLGNG 291
TC I G+ C C G+ GR C E C L NG
Sbjct: 110 TC--IDGIGSFSCDCRSGWEGRFCQREVSFLNCSLDNG 145
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 157 bits (398), Expect = 2e-38
Identities = 103/278 (37%), Positives = 137/278 (49%), Gaps = 21/278 (7%)
Query: 379 LLATLPEPASPGRQ--ACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAI-YIGDSFCAGS 435
LL L + GR+ ACG+ + RI+GG G PW A+I + G C GS
Sbjct: 11 LLLVLGAAGTQGRKSAACGQPR-----MSSRIVGGRDGRDGEWPWQASIQHRGAHVCGGS 65
Query: 436 LVHTCWVVSAAHCFSHSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSD 495
L+ WV++AAHCF V LG T+ T + + + + YS + +
Sbjct: 66 LIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSE-DGAR 124
Query: 496 HDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYS-SSL 554
DL L++L+ R S VQP+CLP PG+ P G C++ GWG L V L
Sbjct: 125 GDLALLQLR----RPVPLSARVQPVCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPL 180
Query: 555 REALVPLVADHKCSSPEVYGADIS-------PNMLCAGYFDCKSDACQGDSGGPLACEKN 607
+ VPL+ C GAD+ P LCAGY DACQGDSGGPL C ++
Sbjct: 181 QGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQS 240
Query: 608 GVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWINDRI 645
G L G++SWG GC ++PGVYT VA Y WI R+
Sbjct: 241 GSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWIQARV 278
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 157 bits (398), Expect = 2e-38
Identities = 92/259 (35%), Positives = 137/259 (52%), Gaps = 15/259 (5%)
Query: 389 PGRQACGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAH 447
P ACG+ + R++GG S PW+ +I G CAGSL+ + WV++AAH
Sbjct: 36 PVPPACGKPQQLN-----RVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAH 90
Query: 448 CFSHSPPRDSV-SVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKK 506
CF + + + SV+LG +Q G+ P+ +YS + D+ L+RL
Sbjct: 91 CFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRL--- 147
Query: 507 GDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVS-GYSSSLREALVPLVADH 565
+R S+ V PICLP+ P C I+GWG + + V + +L++ VP++
Sbjct: 148 -ERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSE 206
Query: 566 KCSSPEVYGADISP---NMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGC 622
CS GA P +MLCAGY + + DAC GDSGGPL C+ +G L GIISWG+GC
Sbjct: 207 VCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGC 266
Query: 623 GRLHKPGVYTRVANYVDWI 641
++PGVY ++ + W+
Sbjct: 267 AERNRPGVYISLSAHRSWV 285
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 157 bits (397), Expect = 3e-38
Identities = 88/242 (36%), Positives = 128/242 (52%), Gaps = 11/242 (4%)
Query: 407 RIIGGSSSLPGSHPWLAAIYIGDS-FCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQH 465
RI+GG+ + PW +++ G + C G+L+ WV++AAHCF + + V+ G
Sbjct: 325 RIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREK----VLEGWK 380
Query: 466 FFNRTTDVTQTFGIEKYIPYTLYSVFNPS--DHDLVLIRLKKKGDRCATRSQFVQPICLP 523
+ T+++ Q + S + D+D+ L+RL K T S + P CLP
Sbjct: 381 VYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKP----LTLSAHIHPACLP 436
Query: 524 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 583
G TF C I G+G E S LRE V L+ KC+ VY + ++P M+C
Sbjct: 437 MHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMC 496
Query: 584 AGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWIND 643
AG D+CQGDSGGPL CE+N YL G+ SWG GCG+ +KPGVYT+V + WI
Sbjct: 497 AGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYS 556
Query: 644 RI 645
++
Sbjct: 557 KM 558
Score = 36.6 bits (83), Expect = 0.075
Identities = 40/144 (27%), Positives = 52/144 (36%), Gaps = 23/144 (15%)
Query: 39 GNRTESPEPNATATPAIPTILVTSVTSETPATSAPEAEGPQSGGLP-------------- 84
GN + + P+A A+PA + T +PA ++P P G P
Sbjct: 7 GNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASP--AGTPPGRASPAQASPAGT 64
Query: 85 PPPRAVPSSSSPQAQALTEDGRPCRFPFRYGGRMLHACTSEGSAHRKWCATTHNYDRDRA 144
PP RA P +SP AQA P R A S S+ R A + +
Sbjct: 65 PPGRASPGRASP-AQASPAQASPAR------ASPALASLSRSSSGRSSSARSASVTTSPT 117
Query: 145 WGYCVEATPPPGGPAALDPCASGP 168
Y V ATP P P S P
Sbjct: 118 RVYLVRATPVGAVPIRSSPARSAP 141
>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
Length = 622
Score = 156 bits (394), Expect = 6e-38
Identities = 139/464 (29%), Positives = 192/464 (41%), Gaps = 76/464 (16%)
Query: 236 WCEGTRHTACLSSPCLNGGTCHLIVATGTTVC-ACPPGFAGRLCNIEPD-ERCFLGNGTG 293
WC T P + C + V V A P G N+ P E+C G
Sbjct: 168 WCYTT-------DPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPDRGQQ 220
Query: 294 YRGVASTSASGLSCLAWNS-DLLYQELHVDSVGAAALLGLGPHAYCRNPDNDERP-WCYV 351
Y+G + + GL CLAW S H D A L+ +CRNPD DE WCYV
Sbjct: 221 YQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLV----ENFCRNPDGDEEGVWCYV 276
Query: 352 VKDSALSWEYCRLEACESLTRVQLSPDL-----------LATL-------PEPASPGRQA 393
+ YC L CE + L AT P G
Sbjct: 277 AGKPG-DFGYCDLNYCEEAVEEETGDGLDEDSDRAIEGRTATSEYQTFFNPRTFGSGEAD 335
Query: 394 CGRR---HKK-----------RTFLRPRIIGGSSSLPGSHPWLAAIYIG---DSFCAGSL 436
CG R KK +++ RI+ GS + G PW ++ + C SL
Sbjct: 336 CGLRPLFEKKSLEDKTERELLESYIDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASL 395
Query: 437 VHTCWVVSAAHCFSHSP-----PRDSVSVVLGQHFFNR-TTDVTQTFGIEKYIPYTLYSV 490
+ WV++AAHC + P + + V +G+H R ++ + +EK + Y+
Sbjct: 396 ISDRWVLTAAHCLLYPPWDKNFTENDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW 455
Query: 491 FNPSDHDLVLIRLKKKGDRCATRSQFVQPICLPE---PGSTFPAGHKCQIAGWGHLDE-- 545
D D+ L++LKK S ++ P+CLP+ S AG+K ++ GWG+L E
Sbjct: 456 RENLDRDIALMKLKKP----VAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETW 511
Query: 546 --NVS-GYSSSLREALVPLVADHKCSSPEVYGADISPNMLCAGYFDC---KSDACQGDSG 599
NV G S L+ +P+V C I+ NM CAGY + DAC+GDSG
Sbjct: 512 TANVGKGQPSVLQVVNLPIVERPVCKDST--RIRITDNMFCAGYKPDEGKRGDACEGDSG 569
Query: 600 GPLACEK--NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 641
GP + N Y GI+SWG+GC R K G YT V WI
Sbjct: 570 GPFVMKSPFNNRWYQMGIVSWGEGCDRDGKYGFYTHVFRLKKWI 613
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 22/125 (17%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQ-ELHVDSVGAAALLGLGPHAYCRNPDND 344
C G GT YRG + + SG+ C W S ++ E++ + A L +CRNPD+
Sbjct: 108 CAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADL----QENFCRNPDSS 163
Query: 345 ER-PWCYVVKDSALSWEYCRLEAC------------ESLTRVQLSPDLLATLPEPASPGR 391
PWCY D + + C + C + V LSP L +P+ G+
Sbjct: 164 TTGPWCYTT-DPTVRRQECSIPVCGQDQVTVAMTPRSEGSSVNLSPPLEQCVPD---RGQ 219
Query: 392 QACGR 396
Q GR
Sbjct: 220 QYQGR 224
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 156 bits (394), Expect = 6e-38
Identities = 88/245 (35%), Positives = 134/245 (54%), Gaps = 15/245 (6%)
Query: 407 RIIGGSSSLPGSHPWLAAIYIGD-SFCAGSLVHTCWVVSAAHCFS---HSPPR-DSVSVV 461
RI+GG S+LPG+ PW ++++ + C GS++ W+V+AAHC ++P + + +
Sbjct: 292 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 351
Query: 462 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 521
L Q F + +EK I + Y ++D+ L++L+K T + V+P+C
Sbjct: 352 LRQSFMFYGAG----YQVEKVISHPNYDS-KTKNNDIALMKLQKP----LTFNDLVKPVC 402
Query: 522 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 581
LP PG C I+GWG +E S L A V L+ +C+S VY I+P M
Sbjct: 403 LPNPGMMLQPEQLCWISGWGATEEK-GKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM 461
Query: 582 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 641
+CAG+ D+CQGDSGGPL KN + +L G SWG GC + ++PGVY V + DWI
Sbjct: 462 ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521
Query: 642 NDRIR 646
++R
Sbjct: 522 YRQMR 526
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 156 bits (394), Expect = 6e-38
Identities = 88/245 (35%), Positives = 134/245 (54%), Gaps = 15/245 (6%)
Query: 407 RIIGGSSSLPGSHPWLAAIYIGD-SFCAGSLVHTCWVVSAAHCFS---HSPPR-DSVSVV 461
RI+GG S+LPG+ PW ++++ + C GS++ W+V+AAHC ++P + + +
Sbjct: 255 RIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGI 314
Query: 462 LGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPIC 521
L Q F + +EK I + Y ++D+ L++L+K T + V+P+C
Sbjct: 315 LRQSFMFYGAG----YQVEKVISHPNYDS-KTKNNDIALMKLQKP----LTFNDLVKPVC 365
Query: 522 LPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNM 581
LP PG C I+GWG +E S L A V L+ +C+S VY I+P M
Sbjct: 366 LPNPGMMLQPEQLCWISGWGATEEK-GKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAM 424
Query: 582 LCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 641
+CAG+ D+CQGDSGGPL KN + +L G SWG GC + ++PGVY V + DWI
Sbjct: 425 ICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484
Query: 642 NDRIR 646
++R
Sbjct: 485 YRQMR 489
>gi|205277383 macrophage stimulating 1 (hepatocyte growth
factor-like) [Homo sapiens]
Length = 725
Score = 156 bits (394), Expect = 6e-38
Identities = 121/392 (30%), Positives = 176/392 (44%), Gaps = 46/392 (11%)
Query: 271 PGFAGRLC--------NIEPDERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVD 322
PG C ++ P + C+ G G YRG S + G+ C W+++ ++
Sbjct: 362 PGMRAAFCYQIRRCTDDVRPQD-CYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTF 420
Query: 323 SVGAAALLGLGPHAYCRNPDNDER-PWCYVVKDSALSWEYCRLEACESLTRVQLSPDLLA 381
+ A L +CRNPD D PWCY + D ++YC L C P +L
Sbjct: 421 TSEPHAQL---EENFCRNPDGDSHGPWCYTM-DPRTPFDYCALRRCAD----DQPPSIL- 471
Query: 382 TLPEPASPGRQACGRRHKKRTFLRP--RIIGGSSSLPGSHPWLAAIYI--GDSFCAGSLV 437
P + CG+R + R R++GG PG+ PW ++ G FC GSLV
Sbjct: 472 --DPPDQVQFEKCGKRVDRLDQRRSKLRVVGGH---PGNSPWTVSLRNRQGQHFCGGSLV 526
Query: 438 HTCWVVSAAHCFSHSP-PRDSVSVVLGQHFFN--RTTDVTQTFGIEKYIPYTLYSVFNPS 494
W+++A CFS P V LG F N Q + K V PS
Sbjct: 527 KEQWILTARQCFSSCHMPLTGYEVWLGTLFQNPQHGEPSLQRVPVAKM-------VCGPS 579
Query: 495 DHDLVLIRLKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSL 554
LVL++L +R T +Q V ICLP P G KC+IAGWG + +G + L
Sbjct: 580 GSQLVLLKL----ERSVTLNQRVALICLPPEWYVVPPGTKCEIAGWG--ETKGTGNDTVL 633
Query: 555 REALVPLVADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYG 614
AL+ ++++ +C+ + + + +C AC+GD GGPLAC + L G
Sbjct: 634 NVALLNVISNQECNIK--HRGRVRESEMCTEGLLAPVGACEGDYGGPLACFTHNCWVLEG 691
Query: 615 IISWGDGCGRLHKPGVYTRVANYVDWINDRIR 646
II C R P V+TRV+ +VDWI+ +R
Sbjct: 692 IIIPNRVCARSRWPAVFTRVSVFVDWIHKVMR 723
Score = 60.8 bits (146), Expect = 4e-09
Identities = 37/101 (36%), Positives = 45/101 (44%), Gaps = 6/101 (5%)
Query: 271 PGFAGRLCNIEP--DERCFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAA 328
P + C I+ + C NG YRG + SG C W DL + H G
Sbjct: 188 PAVRFQSCGIKSCREAACVWCNGEEYRGAVDRTESGRECQRW--DLQHPHQHPFEPGKFL 245
Query: 329 LLGLGPHAYCRNPDNDERPWCYVVKDSALSWEYCRLEACES 369
GL + YCRNPD ERPWCY D + E+C L C S
Sbjct: 246 DQGLDDN-YCRNPDGSERPWCYTT-DPQIEREFCDLPRCGS 284
Score = 58.9 bits (141), Expect = 1e-08
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 3/89 (3%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
CF G G GYRG A+T+ +G+ C W++ + +Q A L +CRNPD E
Sbjct: 297 CFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDL---RENFCRNPDGSE 353
Query: 346 RPWCYVVKDSALSWEYCRLEACESLTRVQ 374
PWC+ ++ + ++ C R Q
Sbjct: 354 APWCFTLRPGMRAAFCYQIRRCTDDVRPQ 382
Score = 56.6 bits (135), Expect = 7e-08
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 7/83 (8%)
Query: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345
C + NG GYRG +T+ GL C AW+ + ++ GL + +CRNPD D
Sbjct: 124 CIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRN----GLEEN-FCRNPDGDP 178
Query: 346 -RPWCYVVKDSALSWEYCRLEAC 367
PWCY D A+ ++ C +++C
Sbjct: 179 GGPWCYTT-DPAVRFQSCGIKSC 200
>gi|222831592 transmembrane protease, serine 7 [Homo sapiens]
Length = 717
Score = 155 bits (392), Expect = 1e-37
Identities = 91/241 (37%), Positives = 134/241 (55%), Gaps = 14/241 (5%)
Query: 407 RIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHSPPRDSV--SVVLG 463
RIIGG+ +L G PW ++ ++G ++C S++ W++SAAHCF + D + LG
Sbjct: 479 RIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLG 538
Query: 464 QHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKKGDRCATRSQFVQPICLP 523
+ V+ + + + + Y+ D+D+ L++L T Q +QPIC+P
Sbjct: 539 MYVQGNAKFVSP---VRRIVVHEYYNS-QTFDYDIALLQLSIAWPE--TLKQLIQPICIP 592
Query: 524 EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGADISPNMLC 583
G +G KC + GWG E + S L++A V L+ C S YG I+ MLC
Sbjct: 593 PTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVS--TYGI-ITSRMLC 649
Query: 584 AGYFDCKSDACQGDSGGPLACEK--NGVAYLYGIISWGDGCGRLHKPGVYTRVANYVDWI 641
AG K DAC+GDSGGPL+C + +G L GI+SWG G GR + PGVYTRV+N+V WI
Sbjct: 650 AGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWI 709
Query: 642 N 642
+
Sbjct: 710 H 710
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 155 bits (392), Expect = 1e-37
Identities = 89/263 (33%), Positives = 137/263 (52%), Gaps = 32/263 (12%)
Query: 394 CGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAI-YIGDSFCAGSLVHTCWVVSAAHCFSHS 452
CGR+ +I+ G SSL G+ PW A++ + G +C SL+ + W++SAAHCF+
Sbjct: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKK 230
Query: 453 PPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDH----------DLVLIR 502
N + D T FGI PY V N H D+ L++
Sbjct: 231 ---------------NNSKDWTVNFGIVVNKPYMTRKVQNIIFHENYSSPGLHDDIALVQ 275
Query: 503 LKKKGDRCATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLV 562
L ++ + +++++ ICLPE + GWG L N S + L+E + ++
Sbjct: 276 LAEE----VSFTEYIRKICLPEAKMKLSENDNVVVTGWGTLYMNGS-FPVILQEDFLKII 330
Query: 563 ADHKCSSPEVYGADISPNMLCAGYFDCKSDACQGDSGGPLAC-EKNGVAYLYGIISWGDG 621
+ C++ Y ++ MLCAG+ ++DACQ DSGGPLA + + +L GI+SWGDG
Sbjct: 331 DNKICNASYAYSGFVTDTMLCAGFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDG 390
Query: 622 CGRLHKPGVYTRVANYVDWINDR 644
CG+ +KPGVYTRV +Y +WI +
Sbjct: 391 CGKKNKPGVYTRVTSYRNWITSK 413
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 154 bits (390), Expect = 2e-37
Identities = 95/262 (36%), Positives = 141/262 (53%), Gaps = 25/262 (9%)
Query: 394 CGRRHKKRTFLRPRIIGGSSSLPGSHPWLAAIYIGDS------FCAGSLVHTCWVVSAAH 447
CG R R + RIIGG +SL G PW ++ + S C +L+ +CWV++AAH
Sbjct: 619 CGLRLLHRR--QKRIIGGKNSLRGGWPWQVSLRLKSSHGDGRLLCGATLLSSCWVLTAAH 676
Query: 448 CFS-HSPPRDSVSVVLGQHFFNRTTDVTQTFGIEKYIPYTLYSVFNPSDHDLVLIRLKKK 506
CF + S +V +G + + + G+++ + + Y + SD+D+ L+RL+
Sbjct: 677 CFKRYGNSTRSYAVRVGDYHTLVPEEFEEEIGVQQIVIHREYRP-DRSDYDIALVRLQGP 735
Query: 507 GDRCATRSQFVQPICLP----EPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLV 562
++CA S V P CLP P T C I GWG + YS +L++A +PL+
Sbjct: 736 EEQCARFSSHVLPACLPLWRERPQKT---ASNCYITGWG---DTGRAYSRTLQQAAIPLL 789
Query: 563 ADHKCSSPEVYGADISPNMLCAG--YFDCKSDACQGDSGGPLACEKNGVAYL-YGIISWG 619
C E Y + MLCAG + + D+CQGDSGGPL CE+ G +++ YG+ SWG
Sbjct: 790 PKRFCE--ERYKGRFTGRMLCAGNLHEHKRVDSCQGDSGGPLMCERPGESWVVYGVTSWG 847
Query: 620 DGCGRLHKPGVYTRVANYVDWI 641
GCG PGVYT+V+ +V WI
Sbjct: 848 YGCGVKDSPGVYTKVSAFVPWI 869
Score = 33.9 bits (76), Expect = 0.49
Identities = 13/29 (44%), Positives = 16/29 (55%), Gaps = 1/29 (3%)
Query: 335 HAYCRNPDNDERPWC-YVVKDSALSWEYC 362
H +CR+PD RPWC Y + W YC
Sbjct: 135 HNFCRSPDGAGRPWCFYGDARGKVDWGYC 163
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.466
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,875,021
Number of Sequences: 37866
Number of extensions: 2053437
Number of successful extensions: 14752
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 279
Number of HSP's successfully gapped in prelim test: 491
Number of HSP's that attempted gapping in prelim test: 9797
Number of HSP's gapped (non-prelim): 3590
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.