Guide to the Human Genome
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Name: HGF Sequence: fasta or formatted (728aa) NCBI GI: 33859835
Description:

hepatocyte growth factor isoform 1 preproprotein

Referenced in:

Coagulation
Interleukins and Their Receptors
Liver
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [290aa] hepatocyte growth factor isoform 2 precursor
alt prot [285aa] hepatocyte growth factor isoform 4 precursor
alt prot [210aa] hepatocyte growth factor isoform 5 precursor
alt prot [723aa] hepatocyte growth factor isoform 3 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.3         24           1
 C cysteine            5.6         41           1
 D aspartate           5.9         43           3
 E glutamate           5.4         39           2
 F phenylalanine       2.5         18           1
 G glycine             8.0         58           2
 H histidine           3.6         26           2
 I isoleucine          5.8         42           2
 K lysine              6.5         47           2
 L leucine             6.9         50           4
 M methionine          2.2         16           1
 N asparagine          5.5         40           1
 P proline             6.6         48           1
 Q glutamine           3.3         24           1
 R arginine            5.9         43           2
 S serine              5.5         40           2
 T threonine           5.8         42           2
 V valine              4.8         35           2
 W tryptophan          2.6         19           1
 Y tyrosine            4.5         33           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hepatocyte growth factor isoform 1 preproprotein [Ho... 
HGF                   0.990   hepatocyte growth factor isoform 3 precursor 
HGF                   0.388   hepatocyte growth factor isoform 2 precursor 
MST1                  0.386   macrophage stimulating 1 (hepatocyte growth factor-...
HGF                   0.378   hepatocyte growth factor isoform 4 precursor 
PLG                   0.286   plasminogen 
LPA                   0.270   lipoprotein Lp(a) precursor 
HGF                   0.267   hepatocyte growth factor isoform 5 precursor 
PLAT                  0.099   plasminogen activator, tissue isoform 1 preproprotein...
PLAT                  0.099   plasminogen activator, tissue isoform 3 preproprotei...
HGFAC                 0.086   HGF activator preproprotein 
F2                    0.084   coagulation factor II preproprotein 
F12                   0.075   coagulation factor XII precursor 
PLAU                  0.073   plasminogen activator, urokinase isoform 1 preproprot...
HABP2                 0.071   hyaluronan binding protein 2 preproprotein 
PLAU                  0.071   plasminogen activator, urokinase isoform 2 
TPSB2                 0.066   tryptase beta 2 precursor 
PRSS7                 0.065   enterokinase precursor 
KLKB1                 0.064   plasma kallikrein B1 precursor 
TPSAB1                0.064   tryptase alpha/beta 1 precursor 
PRSS8                 0.063   prostasin preproprotein 
HPN                   0.062   hepsin 
HPN                   0.062   hepsin 
KLK6                  0.061   kallikrein-related peptidase 6 isoform A preproprote...
KLK6                  0.061   kallikrein-related peptidase 6 isoform A preproprotei...
KLK13                 0.061   kallikrein 13 precursor 
PRSS33                0.060   protease, serine, 33 
TMPRSS3               0.060   transmembrane protease, serine 3 isoform 1 
PRSS1                 0.060   protease, serine, 1 preproprotein 
PRSS27                0.059   marapsin 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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