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Search of human proteins with 4503729
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503729 FK506 binding protein 52 [Homo sapiens]
(459 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503729 FK506 binding protein 52 [Homo sapiens] 914 0.0
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 519 e-147
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 519 e-147
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 519 e-147
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 268 6e-72
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens] 104 1e-22
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens] 104 1e-22
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa... 99 6e-21
gi|52630440 FK506-binding protein 8 [Homo sapiens] 93 4e-19
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens] 93 6e-19
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens] 93 6e-19
gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens] 93 6e-19
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi... 92 1e-18
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 92 1e-18
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 92 1e-18
gi|4826932 peptidylprolyl isomerase D [Homo sapiens] 91 2e-18
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens] 90 4e-18
gi|33469985 FK506 binding protein 9 [Homo sapiens] 85 2e-16
gi|192448443 FK506 binding protein 10 [Homo sapiens] 79 7e-15
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H... 77 3e-14
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H... 77 3e-14
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo... 76 6e-14
gi|27262638 sperm associated antigen 1 [Homo sapiens] 75 2e-13
gi|27262636 sperm associated antigen 1 [Homo sapiens] 75 2e-13
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H... 74 3e-13
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s... 74 4e-13
gi|201860300 aryl hydrocarbon receptor interacting protein [Homo... 71 2e-12
gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled... 70 4e-12
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa... 70 4e-12
gi|74272280 aryl hydrocarbon receptor interacting protein-like 1... 67 4e-11
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 914 bits (2362), Expect = 0.0
Identities = 459/459 (100%), Positives = 459/459 (100%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW
Sbjct: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
Query: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP
Sbjct: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
Query: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD
Sbjct: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
Query: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN
Sbjct: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
Query: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL
Sbjct: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
Query: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG
Sbjct: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
Query: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE
Sbjct: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
Query: 421 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 459
EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA
Sbjct: 421 EENKAKAEASSGDHPTDTEMKEEQKSNTAGSQSQVETEA 459
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 519 bits (1336), Expect = e-147
Identities = 252/454 (55%), Positives = 340/454 (74%), Gaps = 11/454 (2%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
KIP NATL FE+EL +FKGEDL E DGGIIRR + +GEGY+ PNEGA VE+ LEG
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
Query: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN
Sbjct: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238
Query: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
AEL YE+ LKSFEKAKESWEM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWL
Sbjct: 239 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298
Query: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
E E S +E++ +++ LA+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRG
Sbjct: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358
Query: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
EA L +N+FE A+ DF+KVL++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE
Sbjct: 359 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418
Query: 421 EENKAKAEASSG---------DHPTDTEMKEEQK 445
++ K +A + G + TD++ EE+K
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEK 452
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 519 bits (1336), Expect = e-147
Identities = 252/454 (55%), Positives = 340/454 (74%), Gaps = 11/454 (2%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
KIP NATL FE+EL +FKGEDL E DGGIIRR + +GEGY+ PNEGA VE+ LEG
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
Query: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN
Sbjct: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238
Query: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
AEL YE+ LKSFEKAKESWEM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWL
Sbjct: 239 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298
Query: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
E E S +E++ +++ LA+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRG
Sbjct: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358
Query: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
EA L +N+FE A+ DF+KVL++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE
Sbjct: 359 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418
Query: 421 EENKAKAEASSG---------DHPTDTEMKEEQK 445
++ K +A + G + TD++ EE+K
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEK 452
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 519 bits (1336), Expect = e-147
Identities = 252/454 (55%), Positives = 340/454 (74%), Gaps = 11/454 (2%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
KIP NATL FE+EL +FKGEDL E DGGIIRR + +GEGY+ PNEGA VE+ LEG
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLFE--DGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
Query: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPN 240
++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P Y FG GK KF I PN
Sbjct: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPN 238
Query: 241 AELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWL 300
AEL YE+ LKSFEKAKESWEM+++EKLEQ+ IVKE+GTVYFK GKY QA++QY KIVSWL
Sbjct: 239 AELIYEVTLKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWL 298
Query: 301 EYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRG 360
E E S +E++ +++ LA+ LNLAMC+LKL+ ++ A+E C+KAL LDS NEKGL+RRG
Sbjct: 299 EMEYGLSEKESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRG 358
Query: 361 EAHLAVNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAE 420
EA L +N+FE A+ DF+KVL++ P NKAA+ Q+++CQ++ + R++++YANMF++ AE
Sbjct: 359 EAQLLMNEFESAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNERDRRIYANMFKKFAE 418
Query: 421 EENKAKAEASSG---------DHPTDTEMKEEQK 445
++ K +A + G + TD++ EE+K
Sbjct: 419 QDAKEEANKAMGKKTSEGVTNEKGTDSQAMEEEK 452
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 268 bits (686), Expect = 6e-72
Identities = 128/223 (57%), Positives = 167/223 (74%), Gaps = 2/223 (0%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGW 60
MT +E + +A + +G DI+ K+D GVLK++KR G G E PMIGD+V+VHY G
Sbjct: 1 MTTDEGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGK 60
Query: 61 LLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPP 120
L +G KFDSS DR + F F LGKG+VIKAWDI +ATMK GE+CH+ CKPEYAYGSAGS P
Sbjct: 61 LSNGKKFDSSHDRNEPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAGSLP 120
Query: 121 KIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD 180
KIP NATL FE+EL +FKGEDL EDGGIIRR + +GEGY+ PNEGA VE+ LEG
Sbjct: 121 KIPSNATLFFEIELLDFKGEDLF--EDGGIIRRTKRKGEGYSNPNEGATVEIHLEGRCGG 178
Query: 181 KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKP 223
++FD R++ F +GEGE+ D+P G+++A+++M++ E I+YL P
Sbjct: 179 RMFDCRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGP 221
Score = 55.5 bits (132), Expect = 1e-07
Identities = 39/122 (31%), Positives = 63/122 (51%), Gaps = 10/122 (8%)
Query: 138 KGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-KLFDQRELR-----FE 191
+GED+T ++D G+++ ++ G G P G V V +G + K FD R F
Sbjct: 21 QGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNGKKFDSSHDRNEPFVFS 80
Query: 192 IGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKS 251
+G+G+ + + + M+KGE + KP YA+GS G +IP NA L +E+ L
Sbjct: 81 LGKGQVIK---AWDIGVATMKKGEICHLLCKPEYAYGSAGSLP-KIPSNATLFFEIELLD 136
Query: 252 FE 253
F+
Sbjct: 137 FK 138
>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 104 bits (260), Expect = 1e-22
Identities = 51/98 (52%), Positives = 62/98 (63%)
Query: 41 GTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVG 100
G G P G VHYTG L DG KFDSS DR F F LGK EVI+ W+ +A M VG
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70
Query: 101 EVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFK 138
+ +T P+YAYG+ G P IPP+ATLVF+VEL + +
Sbjct: 71 QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 10/102 (9%)
Query: 158 GEGYAKPNEGAIVEVALEGYYKD-KLFDQ-----RELRFEIGEGENLDLPYGLERAIQRM 211
G+G P G V G +D K FD + +F +G+ E + G E + +M
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIR---GWEEGVAQM 67
Query: 212 EKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE 253
G+ + + + P YA+G+ G IPP+A L +++ L E
Sbjct: 68 SVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 104 bits (260), Expect = 1e-22
Identities = 51/98 (52%), Positives = 62/98 (63%)
Query: 41 GTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVG 100
G G P G VHYTG L DG KFDSS DR F F LGK EVI+ W+ +A M VG
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGWEEGVAQMSVG 70
Query: 101 EVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFK 138
+ +T P+YAYG+ G P IPP+ATLVF+VEL + +
Sbjct: 71 QRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE 108
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/102 (28%), Positives = 48/102 (47%), Gaps = 10/102 (9%)
Query: 158 GEGYAKPNEGAIVEVALEGYYKD-KLFDQ-----RELRFEIGEGENLDLPYGLERAIQRM 211
G+G P G V G +D K FD + +F +G+ E + G E + +M
Sbjct: 11 GDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIR---GWEEGVAQM 67
Query: 212 EKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE 253
G+ + + + P YA+G+ G IPP+A L +++ L E
Sbjct: 68 SVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
sapiens]
Length = 108
Score = 99.4 bits (246), Expect = 6e-21
Identities = 48/98 (48%), Positives = 60/98 (61%)
Query: 41 GTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVG 100
G G P G VHYTG L +G KFDSS DR F F +GK EVIK ++ A M +G
Sbjct: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAAQMSLG 70
Query: 101 EVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFK 138
+ +TC P+ AYG+ G P IPPNATL+F+VEL +
Sbjct: 71 QRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108
Score = 37.4 bits (85), Expect = 0.029
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Query: 158 GEGYAKPNEGAIVEVALEGYYKD-KLFDQ-----RELRFEIGEGENLDLPYGLERAIQRM 211
G+G P +G V G ++ K FD + +F IG+ E + G E +M
Sbjct: 11 GDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIK---GFEEGAAQM 67
Query: 212 EKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE 253
G+ + + P A+G+ G IPPNA L +++ L + E
Sbjct: 68 SLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 93.2 bits (230), Expect = 4e-19
Identities = 72/261 (27%), Positives = 128/261 (49%), Gaps = 11/261 (4%)
Query: 160 GYAKPNEGAIVEVALEGYYKD--KLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHS 217
G ++P +G +V V L+ ++ ++ ++ EL F +G+ D+ L+ ++ M+ GE +
Sbjct: 113 GSSRPVKGQVVTVHLQTSLENGTRVQEEPELVFTLGD---CDVIQALDLSVPLMDVGETA 169
Query: 218 IVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERG 277
+V Y +G G IPP+A L E+ LK+ + + +E++ + +E G
Sbjct: 170 MVTADSKYCYGPQGSRSPYIPPHAALCLEVTLKTAVDGPDLEMLTGQERVALANRKRECG 229
Query: 278 TVYFKEGKYKQALLQY----KKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQ 333
+++ + A Y K I S + + +F EEAQ Q L++ NLA LKL
Sbjct: 230 NAHYQRADFVLAANSYDLAIKAITSSAKVDMTFE-EEAQLLQ-LKVKCLNNLAASQLKLD 287
Query: 334 AFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQL 393
+ AA+ SC+ LE +N K LFR+G+ ++ A + L+L P+NK +L
Sbjct: 288 HYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAEL 347
Query: 394 AVCQQRIRRQLAREKKLYANM 414
+ ++ Q + E LY M
Sbjct: 348 SKLVKKHAAQRSTETALYRKM 368
Score = 62.8 bits (151), Expect = 6e-10
Identities = 47/137 (34%), Positives = 67/137 (48%), Gaps = 10/137 (7%)
Query: 1 MTAEEMKATESGAQSAPLPMEGVDISPKQDEGVL--KVIKREGTGTEMPMIGDRVFVHYT 58
+ E + A E AP P E +DI G+L K + G+ P+ G V VH
Sbjct: 72 LAREFLAAMEPEPAPAPAPEEWLDIL---GNGLLRKKTLVPGPPGSSRPVKGQVVTVHLQ 128
Query: 59 GWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGS 118
L +GT+ + + + F LG +VI+A D+++ M VGE +T +Y YG GS
Sbjct: 129 TSLENGTR----VQEEPELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGS 184
Query: 119 -PPKIPPNATLVFEVEL 134
P IPP+A L EV L
Sbjct: 185 RSPYIPPHAALCLEVTL 201
>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
Length = 322
Score = 92.8 bits (229), Expect = 6e-19
Identities = 76/287 (26%), Positives = 139/287 (48%), Gaps = 24/287 (8%)
Query: 147 DGGIIRRIQTRGEGYAKPNEGAIVEVALEGY--YKDKLFDQRELR-----FEIGEGENLD 199
D G+++ + G G + +++ V GY + D+ FD R ++GE L
Sbjct: 30 DRGVLKDVIREGAGDLVAPDASVL-VKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITL- 87
Query: 200 LPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESW 259
+G+E + M +GE + KP+YA+G++G IPPN + +E+ L F ES
Sbjct: 88 --WGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDCAESD 144
Query: 260 E---MNSEEK--------LEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSN 308
+ +++E++ L+ + +E G F++ ++ A ++YK+ + L S+
Sbjct: 145 KFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSA-PP 203
Query: 309 EEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVND 368
EE +A +L LNL+ +LKL + A+ +AL +D N K LFR G+A L + +
Sbjct: 204 EEQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACLLLTE 263
Query: 369 FELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMF 415
++ AR + + P N +L R + +EK+++ MF
Sbjct: 264 YQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 310
Score = 77.4 bits (189), Expect = 3e-14
Identities = 43/109 (39%), Positives = 63/109 (57%), Gaps = 2/109 (1%)
Query: 30 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTK-FDSSLDRKDKFSFDLGKGEVIK 88
D GVLK + REG G ++ V V Y+G+L + FDS+ RK LG+ +
Sbjct: 30 DRGVLKDVIREGAG-DLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLW 88
Query: 89 AWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEF 137
++ + +M+ GE+ KP YAYG+ G PP IPPN T++FE+EL +F
Sbjct: 89 GMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDF 137
>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
Length = 327
Score = 92.8 bits (229), Expect = 6e-19
Identities = 76/287 (26%), Positives = 139/287 (48%), Gaps = 24/287 (8%)
Query: 147 DGGIIRRIQTRGEGYAKPNEGAIVEVALEGY--YKDKLFDQRELR-----FEIGEGENLD 199
D G+++ + G G + +++ V GY + D+ FD R ++GE L
Sbjct: 35 DRGVLKDVIREGAGDLVAPDASVL-VKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITL- 92
Query: 200 LPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESW 259
+G+E + M +GE + KP+YA+G++G IPPN + +E+ L F ES
Sbjct: 93 --WGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIELLDFLDCAESD 149
Query: 260 E---MNSEEK--------LEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSN 308
+ +++E++ L+ + +E G F++ ++ A ++YK+ + L S+
Sbjct: 150 KFCALSAEQQDQFPLQKVLKVAATEREFGNYLFRQNRFYDAKVRYKRALLLLRRRSA-PP 208
Query: 309 EEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVND 368
EE +A +L LNL+ +LKL + A+ +AL +D N K LFR G+A L + +
Sbjct: 209 EEQHLVEAAKLPVLLNLSFTYLKLDRPTIALCYGEQALIIDQKNAKALFRCGQACLLLTE 268
Query: 369 FELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMF 415
++ AR + + P N +L R + +EK+++ MF
Sbjct: 269 YQKARDFLVRAQKEQPFNHDINNELKKLASCYRDYVDKEKEMWHRMF 315
Score = 77.4 bits (189), Expect = 3e-14
Identities = 43/109 (39%), Positives = 63/109 (57%), Gaps = 2/109 (1%)
Query: 30 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTK-FDSSLDRKDKFSFDLGKGEVIK 88
D GVLK + REG G ++ V V Y+G+L + FDS+ RK LG+ +
Sbjct: 35 DRGVLKDVIREGAG-DLVAPDASVLVKYSGYLEHMDRPFDSNYFRKTPRLMKLGEDITLW 93
Query: 89 AWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEF 137
++ + +M+ GE+ KP YAYG+ G PP IPPN T++FE+EL +F
Sbjct: 94 GMELGLLSMRRGELARFLFKPNYAYGTLGCPPLIPPNTTVLFEIELLDF 142
>gi|17149853 WAF-1/CIP1 stabilizing protein 39 [Homo sapiens]
Length = 349
Score = 92.8 bits (229), Expect = 6e-19
Identities = 72/258 (27%), Positives = 116/258 (44%), Gaps = 25/258 (9%)
Query: 138 KGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQRELRFEIGEGEN 197
+ DL DG +++I RG G KP G+ V G+ + +G G
Sbjct: 92 QASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPW 151
Query: 198 LDLPYG--LERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKA 255
+ +G +E+ ++ M +GE + + Q+P ++ L L SF +
Sbjct: 152 REETWGELIEKCLESMCQGEEA----------------ELQLPGHSGPPVRLTLASFTQG 195
Query: 256 KESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQ 315
++SWE+ + EK + + RGT F+ G + A Y + + L E
Sbjct: 196 RDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRALRLLLTLPPPGPPE----- 250
Query: 316 ALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARAD 375
R H NLA C L L A +SC++ LE + + K L+RRG A A+ + E A AD
Sbjct: 251 --RTVLHANLAACQLLLGQPQLAAQSCDRVLEREPGHLKALYRRGVAQAALGNLEKATAD 308
Query: 376 FQKVLQLYPNNKAAKTQL 393
+KVL + P N+AA+ +L
Sbjct: 309 LKKVLAIDPKNRAAQEEL 326
>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
Length = 142
Score = 91.7 bits (226), Expect = 1e-18
Identities = 46/89 (51%), Positives = 56/89 (62%)
Query: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
GD + +HYTG L DGT+FDSSL + F F LG G+VIK WD + M GE +
Sbjct: 49 GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 108
Query: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFK 138
E YG G+PPKIP ATLVFEVEL + +
Sbjct: 109 ELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 91.7 bits (226), Expect = 1e-18
Identities = 46/89 (51%), Positives = 56/89 (62%)
Query: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
GD + +HYTG L DGT+FDSSL + F F LG G+VIK WD + M GE +
Sbjct: 49 GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 108
Query: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFK 138
E YG G+PPKIP ATLVFEVEL + +
Sbjct: 109 ELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 91.7 bits (226), Expect = 1e-18
Identities = 46/89 (51%), Positives = 56/89 (62%)
Query: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
GD + +HYTG L DGT+FDSSL + F F LG G+VIK WD + M GE +
Sbjct: 49 GDVLHMHYTGKLEDGTEFDSSLPQNQPFVFSLGTGQVIKGWDQGLLGMCEGEKRKLVIPS 108
Query: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFK 138
E YG G+PPKIP ATLVFEVEL + +
Sbjct: 109 ELGYGERGAPPKIPGGATLVFEVELLKIE 137
>gi|4826932 peptidylprolyl isomerase D [Homo sapiens]
Length = 370
Score = 91.3 bits (225), Expect = 2e-18
Identities = 45/144 (31%), Positives = 83/144 (57%), Gaps = 1/144 (0%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESS-FSNEEAQKAQALRLASHLNLAMCHLK 331
+K G +FK ++ A+ +Y +++ +++ + + K Q + L+ LN+ C LK
Sbjct: 226 LKNIGNTFFKSQNWEMAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLK 285
Query: 332 LQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKT 391
+ + AI+SC +ALELD +N K L+RR + + +++ A AD +K + P +KA +
Sbjct: 286 MSNWQGAIDSCLEALELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQA 345
Query: 392 QLAVCQQRIRRQLAREKKLYANMF 415
+L +Q+I+ Q +EK +YA MF
Sbjct: 346 ELLKVKQKIKAQKDKEKAVYAKMF 369
>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
Length = 224
Score = 90.1 bits (222), Expect = 4e-18
Identities = 53/118 (44%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
Query: 27 PKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK-------FSF 79
PK + VLK +G T P GD V YTG L DGT FD+++ K SF
Sbjct: 109 PKYTKSVLK----KGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
Query: 80 DLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSP-PKIPPNATLVFEVELFE 136
+G G+VI+ WD A+ TM GE + +PE+AYG G P KIPPNA L FEVEL +
Sbjct: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVD 222
Score = 50.1 bits (118), Expect = 4e-06
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 136 EFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-------------KL 182
E K E+ +E + + +G+ P +G +V G +D K
Sbjct: 97 ETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKK 156
Query: 183 FDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAE 242
+ + L F++G G+ + G + A+ M KGE + + ++P +A+G G+ +IPPNA+
Sbjct: 157 KNAKPLSFKVGVGKVIR---GWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAK 213
Query: 243 LKYELHL 249
L +E+ L
Sbjct: 214 LTFEVEL 220
>gi|33469985 FK506 binding protein 9 [Homo sapiens]
Length = 570
Score = 84.7 bits (208), Expect = 2e-16
Identities = 73/239 (30%), Positives = 105/239 (43%), Gaps = 25/239 (10%)
Query: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
GD V HY G DG KFDSS DR F+ +GKG++I D A+ M V E + P
Sbjct: 54 GDFVRYHYVGTFPDGQKFDSSYDRDSTFNVFVGKGQLITGMDQALVGMCVNERRFVKIPP 113
Query: 110 EYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKP----- 164
+ AYG+ G IPPN+ L F+V L D+ ED Q + Y KP
Sbjct: 114 KLAYGNEGVSGVIPPNSVLHFDVLLM-----DIWNSED-------QVQIHTYFKPPSCPR 161
Query: 165 --NEGAIVEVALEGYYKD-KLFDQRELR---FEIGEGENLDLPYGLERAIQRMEKGEHSI 218
V G + D LFD R ++ G +P G+++ + M GE I
Sbjct: 162 TIQVSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIP-GMDKGLLGMCVGEKRI 220
Query: 219 VYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERG 277
+ + P A+G G K IP A L +++ L K+S + ++ E + + G
Sbjct: 221 ITIPPFLAYGEDGDGK-DIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSG 278
Score = 81.6 bits (200), Expect = 1e-15
Identities = 64/235 (27%), Positives = 106/235 (45%), Gaps = 16/235 (6%)
Query: 49 IGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCK 108
+ D V HY G LDGT FDSS +R + +G G +I D + M VGE IT
Sbjct: 165 VSDFVRYHYNGTFLDGTLFDSSHNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKRIITIP 224
Query: 109 PEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGII----RRIQTRGEGYAKP 164
P AYG G IP A+LVF+V L + + + ++ RI G+
Sbjct: 225 PFLAYGEDGDGKDIPGQASLVFDVALLDLHNPKDSISIENKVVPENCERISQSGDFLRYH 284
Query: 165 NEGAIVEVAL--EGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLK 222
G +++ L Y +++ FD IG+G + G++ + + GE + +
Sbjct: 285 YNGTLLDGTLFDSSYSRNRTFDT-----YIGQGYVIP---GMDEGLLGVCIGEKRRIVVP 336
Query: 223 PSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERG 277
P +G G+ IP +A L +++H+ F +S + S K +++ ++G
Sbjct: 337 PHLGYGEEGRG--NIPGSAVLVFDIHVIDFHNPSDSISITSHYKPPDCSVLSKKG 389
Score = 65.1 bits (157), Expect = 1e-10
Identities = 33/87 (37%), Positives = 48/87 (55%)
Query: 50 GDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCKP 109
GD + HY LLDGT DS+ + ++ LG G+V+ D+ + M VGE + P
Sbjct: 389 GDYLKYHYNASLLDGTLLDSTWNLGKTYNIVLGSGQVVLGMDMGLREMCVGEKRTVIIPP 448
Query: 110 EYAYGSAGSPPKIPPNATLVFEVELFE 136
YG AG ++P +A LVF++EL E
Sbjct: 449 HLGYGEAGVDGEVPGSAVLVFDIELLE 475
>gi|192448443 FK506 binding protein 10 [Homo sapiens]
Length = 582
Score = 79.3 bits (194), Expect = 7e-15
Identities = 68/245 (27%), Positives = 105/245 (42%), Gaps = 11/245 (4%)
Query: 23 VDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLG 82
+D+ K+D + + R M GD V HY G LLDGT FD+S + + +G
Sbjct: 147 LDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVG 206
Query: 83 KGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDL 142
G +IK D + M GE I P AYG G IPP A+LVF V L D+
Sbjct: 207 SGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLI-----DV 261
Query: 143 TEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-KLFD---QRELRFEIGEGENL 198
+D + ++ + G + G D LFD R + G+
Sbjct: 262 HNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGY 321
Query: 199 DLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKES 258
+P G+++ +Q GE + + P A+G G +IP +A L + +H+ F +
Sbjct: 322 IIP-GMDQGLQGACMGERRRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVIDFHNPADV 379
Query: 259 WEMNS 263
E+ +
Sbjct: 380 VEIRT 384
Score = 76.6 bits (187), Expect = 4e-14
Identities = 67/239 (28%), Positives = 103/239 (43%), Gaps = 19/239 (7%)
Query: 23 VDISPKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLG 82
+D+ +D L+ ++ GD + HY G L+DGT FDSS R ++ +G
Sbjct: 259 IDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIG 318
Query: 83 KGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFEFKG-ED 141
+G +I D + +GE IT P AYG G+ KIP +A L+F V + +F D
Sbjct: 319 QGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPAD 378
Query: 142 LTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKDKLFDQREL--RFEIGEGENLD 199
+ E I+T NE + + +Y L D +L + G +
Sbjct: 379 VVE---------IRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEAT 429
Query: 200 LP-----YGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELHLKSFE 253
L GL+ +Q M GE + + P A G G +P +A L +E+ L S E
Sbjct: 430 LGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGAR--GVPGSAVLLFEVELVSRE 486
Score = 75.1 bits (183), Expect = 1e-13
Identities = 63/224 (28%), Positives = 92/224 (41%), Gaps = 17/224 (7%)
Query: 49 IGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAIATMKVGEVCHITCK 108
+GD V HY G DG KFDSS DR + +G G +I D + M V E +
Sbjct: 61 MGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVGRLITGMDRGLMGMCVNERRRLIVP 120
Query: 109 PEYAYGSAGSPPKIPPNATLVFEVELFEFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGA 168
P YGS G IPP+ATL F+V L D+ +ED + + +G
Sbjct: 121 PHLGYGSIGLAGLIPPDATLYFDVVLL-----DVWNKEDTVQVSTLLRPPHCPRMVQDGD 175
Query: 169 IVEVALEGYYKDKLFDQRELRFEIGEGENLD-------LPYGLERAIQRMEKGEHSIVYL 221
V +Y L D +G D L G+++ + M GE + +
Sbjct: 176 FVRY----HYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIII 231
Query: 222 KPSYAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEE 265
P A+G G IPP A L + + L K++ ++ + E
Sbjct: 232 PPFLAYGEKGYGTV-IPPQASLVFHVLLIDVHNPKDAVQLETLE 274
>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
sapiens]
Length = 506
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/194 (29%), Positives = 101/194 (52%), Gaps = 23/194 (11%)
Query: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305
++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++
Sbjct: 101 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 151
Query: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365
A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A
Sbjct: 152 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 203
Query: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKA 425
+ A+ DF+ VL L P NK A T+L+ +I+++L EK + ++F + +N
Sbjct: 204 LGKLNEAKQDFETVLLLEPGNKQAVTELS----KIKKELI-EKGHWDDVFLDSTQRQNVV 258
Query: 426 KAEASSGDHPTDTE 439
K + HP T+
Sbjct: 259 K-PIDNPPHPGSTK 271
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/104 (32%), Positives = 56/104 (53%), Gaps = 7/104 (6%)
Query: 324 NLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLY 383
N A + +L+ F+ A CN A+ L+ + K RRG A A+ E A+ D+++VL+L
Sbjct: 13 NRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELE 72
Query: 384 PNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424
PNN A +L ++I + LA ++ Y A++ + E E K
Sbjct: 73 PNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 112
>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
sapiens]
Length = 665
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/194 (29%), Positives = 101/194 (52%), Gaps = 23/194 (11%)
Query: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305
++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 310
Query: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365
A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A
Sbjct: 311 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Query: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEEENKA 425
+ A+ DF+ VL L P NK A T+L+ +I+++L EK + ++F + +N
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELS----KIKKELI-EKGHWDDVFLDSTQRQNVV 417
Query: 426 KAEASSGDHPTDTE 439
K + HP T+
Sbjct: 418 K-PIDNPPHPGSTK 430
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 22/178 (12%)
Query: 250 KSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309
+S + ES E +++ ++KE+G YFK+GKY +A+ Y K
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK-------------- 158
Query: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDF 369
A N A + +L+ F+ A CN A+ L+ + K RRG A A+
Sbjct: 159 -GMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217
Query: 370 ELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424
E A+ D+++VL+L PNN A +L ++I + LA ++ Y A++ + E E K
Sbjct: 218 EEAKKDYERVLELEPNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 271
>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
sapiens]
Length = 309
Score = 76.3 bits (186), Expect = 6e-14
Identities = 44/152 (28%), Positives = 78/152 (51%), Gaps = 15/152 (9%)
Query: 239 PNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVS 298
P+ K KS E + S +E++ ++KE G K+G +K+A+ +Y + +
Sbjct: 162 PSENHKEMAKSKSKETTATKNRVPSAGDVEKARVLKEEGNELVKKGNHKKAIEKYSESLL 221
Query: 299 WLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFR 358
ES A++ N A+C+L L+ ++ A++ C +AL+LD N K +R
Sbjct: 222 CSNLES---------------ATYSNRALCYLVLKQYTEAVKDCTEALKLDGKNVKAFYR 266
Query: 359 RGEAHLAVNDFELARADFQKVLQLYPNNKAAK 390
R +AH A+ D++ + AD +LQ+ P N A+
Sbjct: 267 RAQAHKALKDYKSSFADISNLLQIEPRNGPAQ 298
Score = 50.8 bits (120), Expect = 3e-06
Identities = 44/183 (24%), Positives = 76/183 (41%), Gaps = 10/183 (5%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
++ G F+ G+Y +A Y + + L+ + S EE + N A CHLK
Sbjct: 12 LRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEES-------VLYSNRAACHLKD 64
Query: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQ 392
I+ C AL L + K L RR A+ A+ + +A D++ VLQ+ N +A
Sbjct: 65 GNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSAVEG 124
Query: 393 LAVCQQRIRRQLAREKKLYANMFERLAEEENKAKAEASSGDHPTDTEMKEEQKSNTAGSQ 452
+ + + L E +L + K S +H EM + + T ++
Sbjct: 125 INRMTRALMDSLGPEWRLKLPSIPLVPVSAQKRWNSLPSENH---KEMAKSKSKETTATK 181
Query: 453 SQV 455
++V
Sbjct: 182 NRV 184
>gi|27262638 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/194 (27%), Positives = 87/194 (44%), Gaps = 24/194 (12%)
Query: 248 HLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFS 307
HL E ++ + +EK +T KE+G F G Y++A++ Y + +S L +++
Sbjct: 187 HLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTVVAYN 246
Query: 308 NEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVN 367
N A +KLQ +++A + C K LEL+ N K L RR + N
Sbjct: 247 NR----------------AQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQN 290
Query: 368 DFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLA------REKKLYANMFERLAEE 421
A D KVL + P+N AK L+ ++ ++ A + K++ E +E
Sbjct: 291 KLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDE 350
Query: 422 ENKA--KAEASSGD 433
E K+ K E GD
Sbjct: 351 EGKSGRKHEDGGGD 364
Score = 59.3 bits (142), Expect = 7e-09
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 15/121 (12%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
+KE G + YK AL +Y + + +N+E A + N A+C+LKL
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIYTNRALCYLKL 670
Query: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQ 392
F A + C++AL+L N K +RR AH + +++ + D KV+ L P+ AK +
Sbjct: 671 CQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKME 730
Query: 393 L 393
L
Sbjct: 731 L 731
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
+K +G F+ G++ +A +Y ++ LE S E A L + N A C+LK
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGS---EIADDLSIL----YSNRAACYLKE 500
Query: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQL 382
S I+ CN+ALEL + K L RR A+ + + A D++ VLQ+
Sbjct: 501 GNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQI 550
>gi|27262636 sperm associated antigen 1 [Homo sapiens]
Length = 926
Score = 74.7 bits (182), Expect = 2e-13
Identities = 53/194 (27%), Positives = 87/194 (44%), Gaps = 24/194 (12%)
Query: 248 HLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFS 307
HL E ++ + +EK +T KE+G F G Y++A++ Y + +S L +++
Sbjct: 187 HLSKIETRIDTAGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTVVAYN 246
Query: 308 NEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVN 367
N A +KLQ +++A + C K LEL+ N K L RR + N
Sbjct: 247 NR----------------AQAEIKLQNWNSAFQDCEKVLELEPGNVKALLRRATTYKHQN 290
Query: 368 DFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLA------REKKLYANMFERLAEE 421
A D KVL + P+N AK L+ ++ ++ A + K++ E +E
Sbjct: 291 KLREATEDLSKVLDVEPDNDLAKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDE 350
Query: 422 ENKA--KAEASSGD 433
E K+ K E GD
Sbjct: 351 EGKSGRKHEDGGGD 364
Score = 59.3 bits (142), Expect = 7e-09
Identities = 37/121 (30%), Positives = 60/121 (49%), Gaps = 15/121 (12%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
+KE G + YK AL +Y + + +N+E A + N A+C+LKL
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLK-------INNKEC--------AIYTNRALCYLKL 670
Query: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQ 392
F A + C++AL+L N K +RR AH + +++ + D KV+ L P+ AK +
Sbjct: 671 CQFEEAKQDCDQALQLADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILLDPSIIEAKME 730
Query: 393 L 393
L
Sbjct: 731 L 731
Score = 52.0 bits (123), Expect = 1e-06
Identities = 35/110 (31%), Positives = 55/110 (50%), Gaps = 7/110 (6%)
Query: 273 VKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKL 332
+K +G F+ G++ +A +Y ++ LE S E A L + N A C+LK
Sbjct: 448 LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGS---EIADDLSIL----YSNRAACYLKE 500
Query: 333 QAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQL 382
S I+ CN+ALEL + K L RR A+ + + A D++ VLQ+
Sbjct: 501 GNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKAYVDYKTVLQI 550
>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
sapiens]
Length = 631
Score = 73.9 bits (180), Expect = 3e-13
Identities = 49/163 (30%), Positives = 88/163 (53%), Gaps = 17/163 (10%)
Query: 246 ELHLKSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESS 305
++ +KS E ++ ++ +++ +Q+ K+RG +FKEGKY++A+ Y + ++
Sbjct: 260 DIVIKSTEGERK--QIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIA------- 310
Query: 306 FSNEEAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLA 365
A A AL A N AM +LK+Q + A + C +A+ LD + K RRG A
Sbjct: 311 -----ADGANALLPA---NRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTF 362
Query: 366 VNDFELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREK 408
+ A+ DF+ VL L P NK A T+L+ +++ +++ E+
Sbjct: 363 LGKLNEAKQDFETVLLLEPGNKQAVTELSKIKKKPLKKVIIEE 405
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/178 (28%), Positives = 84/178 (47%), Gaps = 22/178 (12%)
Query: 250 KSFEKAKESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNE 309
+S + ES E +++ ++KE+G YFK+GKY +A+ Y K
Sbjct: 113 ESLSQESESEEDGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTK-------------- 158
Query: 310 EAQKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDF 369
A N A + +L+ F+ A CN A+ L+ + K RRG A A+
Sbjct: 159 -GMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKL 217
Query: 370 ELARADFQKVLQLYPNNKAAKTQLAVCQQRIRRQLAREKKLY---ANMFERLAEEENK 424
E A+ D+++VL+L PNN A +L ++I + LA ++ Y A++ + E E K
Sbjct: 218 EEAKKDYERVLELEPNNFEATNEL----RKISQALASKENSYPKEADIVIKSTEGERK 271
>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
sapiens]
Length = 221
Score = 73.6 bits (179), Expect = 4e-13
Identities = 54/166 (32%), Positives = 80/166 (48%), Gaps = 16/166 (9%)
Query: 30 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLL-DGTKFDSSLDRKDKFS--FDLGKGEV 86
+E ++V+ R ++ GD + HY G+L DG+KF S + + F LG G+V
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 87 IKAWDIAIATMKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELF----------E 136
IK DIA+ M GE + P +AYG G KIPP+ATL+FE+EL+
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEGKIPPDATLIFEIELYAVTKGPRSIET 152
Query: 137 FKGEDLTEEED---GGIIRRIQTRGEGYAKPNEGAIVEVALEGYYK 179
FK D+ + I +Q E KP + + + LE +K
Sbjct: 153 FKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFK 198
Score = 39.7 bits (91), Expect = 0.006
Identities = 43/150 (28%), Positives = 71/150 (47%), Gaps = 22/150 (14%)
Query: 138 KGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYY-KD--KLFDQRELR----- 189
K E+ TEE ++ R + + K G ++ +GY KD K + R
Sbjct: 27 KKEESTEEVKIEVLHRPENCSKTSKK---GDLLNAHYDGYLAKDGSKFYCSRTQNEGHPK 83
Query: 190 -FEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELH 248
F +G G+ + GL+ A+ M GE V + PS+A+G G E +IPP+A L +E+
Sbjct: 84 WFVLGVGQVIK---GLDIAMTDMCPGEKRKVVIPPSFAYGKEGYEG-KIPPDATLIFEIE 139
Query: 249 LKSFEKAKESWE------MNSEEKLEQSTI 272
L + K S E M+++ +L ++ I
Sbjct: 140 LYAVTKGPRSIETFKQIDMDNDRQLSKAEI 169
>gi|201860300 aryl hydrocarbon receptor interacting protein [Homo
sapiens]
Length = 330
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/165 (28%), Positives = 81/165 (49%), Gaps = 6/165 (3%)
Query: 256 KESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEY----ESSFSNEEA 311
++ W M EEK + ++ + G ++EG K+A +Y ++ L+ E S E
Sbjct: 165 QDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWI 224
Query: 312 QKAQALRLASHLNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFEL 371
Q Q + LN C L ++ + ++ C+ L +N K F+RG+AH AV + +
Sbjct: 225 QLDQQITPLL-LNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQE 283
Query: 372 ARADFQKVLQLYPN-NKAAKTQLAVCQQRIRRQLAREKKLYANMF 415
A+ADF KVL+L P +L + RIR++ +K + +F
Sbjct: 284 AQADFAKVLELDPALAPVVSRELQALEARIRQKDEEDKARFRGIF 328
Score = 37.7 bits (86), Expect = 0.022
Identities = 25/87 (28%), Positives = 40/87 (45%), Gaps = 5/87 (5%)
Query: 25 ISPKQDEGVLKVIKREGTGTEMPMI--GDRVFVHYTGWLLD--GTKFDSSLDRKDKFSFD 80
I+ +++G+ K + +EG G E+P G + HY D GT D S R
Sbjct: 5 IARLREDGIQKRVIQEGRG-ELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELI 63
Query: 81 LGKGEVIKAWDIAIATMKVGEVCHITC 107
+GK + W+ + TM+ GE+ C
Sbjct: 64 IGKKFKLPVWETIVCTMREGEIAQFLC 90
>gi|225543461 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 1 isoform 1 [Homo sapiens]
Length = 1861
Score = 70.1 bits (170), Expect = 4e-12
Identities = 50/174 (28%), Positives = 83/174 (47%), Gaps = 4/174 (2%)
Query: 275 ERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHLKLQA 334
E G V +K+GK K+A +Y+ + E E+ + LR++ +LNL+ C K
Sbjct: 1294 EEGNVMYKKGKMKEAAQRYQYALRKFPREGF--GEDMRPFNELRVSLYLNLSRCRRKTND 1351
Query: 335 FSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYPNNKAAKTQLA 394
F A E +KALEL + + + R A F A AD Q+ ++L P N+ K LA
Sbjct: 1352 FGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLA 1411
Query: 395 VCQQRIRR-QLAREKKLYANMFERLAEEENKAKAEASS-GDHPTDTEMKEEQKS 446
++ ++ Q ++++K + L + EN+ DH E +EE+ S
Sbjct: 1412 RVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETS 1465
>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
sapiens]
Length = 222
Score = 70.1 bits (170), Expect = 4e-12
Identities = 54/167 (32%), Positives = 81/167 (48%), Gaps = 17/167 (10%)
Query: 30 DEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLL-DGTKFDSSLDRKDKFS--FDLGKGEV 86
+E ++V+ R ++ GD + HY G+L DG+KF S + + F LG G+V
Sbjct: 33 EEVKIEVLHRPENCSKTSKKGDLLNAHYDGYLAKDGSKFYCSRTQNEGHPKWFVLGVGQV 92
Query: 87 IKAWDIAIATMKVGEVCHITCKPEYAYGSAG-SPPKIPPNATLVFEVELF---------- 135
IK DIA+ M GE + P +AYG G + KIPP+ATL+FE+EL+
Sbjct: 93 IKGLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIELYAVTKGPRSIE 152
Query: 136 EFKGEDLTEEED---GGIIRRIQTRGEGYAKPNEGAIVEVALEGYYK 179
FK D+ + I +Q E KP + + + LE +K
Sbjct: 153 TFKQIDMDNDRQLSKAEINLYLQREFEKDEKPRDKSYQDAVLEDIFK 199
Score = 42.0 bits (97), Expect = 0.001
Identities = 42/150 (28%), Positives = 71/150 (47%), Gaps = 21/150 (14%)
Query: 138 KGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYY-KD--KLFDQRELR----- 189
K E+ TEE ++ R + + K G ++ +GY KD K + R
Sbjct: 27 KKEESTEEVKIEVLHRPENCSKTSKK---GDLLNAHYDGYLAKDGSKFYCSRTQNEGHPK 83
Query: 190 -FEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAELKYELH 248
F +G G+ + GL+ A+ M GE V + PS+A+G G + +IPP+A L +E+
Sbjct: 84 WFVLGVGQVIK---GLDIAMTDMCPGEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIE 140
Query: 249 LKSFEKAKESWE------MNSEEKLEQSTI 272
L + K S E M+++ +L ++ I
Sbjct: 141 LYAVTKGPRSIETFKQIDMDNDRQLSKAEI 170
>gi|74272280 aryl hydrocarbon receptor interacting protein-like 1
isoform 3 [Homo sapiens]
Length = 324
Score = 66.6 bits (161), Expect = 4e-11
Identities = 53/212 (25%), Positives = 96/212 (45%), Gaps = 11/212 (5%)
Query: 256 KESWEMNSEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQ 315
+E+W +++ EK++ ++ G FK G+Y++A +Y++ + L + + E+ + Q
Sbjct: 104 RETWNLSNHEKMKAVPVLHGEGNRLFKLGRYEEASSKYQEAIICLR--NLQTKEKPWEVQ 161
Query: 316 ALRLASH-----LNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFE 370
L+L LN C LK + + +E + L K + R AH V +
Sbjct: 162 WLKLEKMINTLILNYCQCLLKKEEYYEVLEHTSDILRHHPGIVKAYYVRARAHAEVWNEA 221
Query: 371 LARADFQKVLQLYPN-NKAAKTQLAVCQQRIRRQLAREKKLYANMFERLAEE---ENKAK 426
A+AD QKVL+L P+ KA + +L + + R+ + E+ NM + A + E +
Sbjct: 222 EAKADLQKVLELEPSMQKAVRRELRLLENRMAEKQEEERLRCRNMLSQGATQPPAEPPTE 281
Query: 427 AEASSGDHPTDTEMKEEQKSNTAGSQSQVETE 458
A S P +AG ++ TE
Sbjct: 282 PPAQSSTEPPAEPPTAPSAELSAGPPAEPATE 313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,000,028
Number of Sequences: 37866
Number of extensions: 783677
Number of successful extensions: 2744
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 2439
Number of HSP's gapped (non-prelim): 296
length of query: 459
length of database: 18,247,518
effective HSP length: 106
effective length of query: 353
effective length of database: 14,233,722
effective search space: 5024503866
effective search space used: 5024503866
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.