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Search of human proteins with 4503727
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
(224 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens] 454 e-128
gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo sapi... 93 2e-19
gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 93 2e-19
gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens] 93 2e-19
gi|4503729 FK506 binding protein 52 [Homo sapiens] 90 1e-18
gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens] 89 3e-18
gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens] 89 3e-18
gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo sa... 84 1e-16
gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens] 81 8e-16
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens] 81 8e-16
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens] 81 8e-16
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens] 81 8e-16
gi|31317231 FK506 binding protein 7 isoform a precursor [Homo sa... 75 5e-14
gi|206725547 FK506 binding protein 7 isoform b precursor [Homo s... 71 9e-13
gi|8923659 FK506 binding protein 14 [Homo sapiens] 69 3e-12
gi|192448443 FK506 binding protein 10 [Homo sapiens] 65 4e-11
gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo sa... 65 4e-11
gi|33469985 FK506 binding protein 9 [Homo sapiens] 62 3e-10
gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo ... 57 1e-08
gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens] 53 2e-07
gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens] 49 3e-06
gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens] 49 3e-06
gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo s... 46 3e-05
gi|118498337 HECT domain containing 1 [Homo sapiens] 45 5e-05
gi|52630440 FK506-binding protein 8 [Homo sapiens] 43 2e-04
gi|53759134 endonuclease G precursor [Homo sapiens] 34 0.089
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 34 0.089
gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens] 33 0.26
gi|42518068 trans-golgi network protein 2 [Homo sapiens] 33 0.26
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 30 1.3
>gi|4503727 FK506 binding protein 3, 25kDa [Homo sapiens]
Length = 224
Score = 454 bits (1169), Expect = e-128
Identities = 224/224 (100%), Positives = 224/224 (100%)
Query: 1 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV 60
MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV
Sbjct: 1 MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLV 60
Query: 61 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD 120
TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD
Sbjct: 61 TAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGD 120
Query: 121 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL 180
KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL
Sbjct: 121 KTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALL 180
Query: 181 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
Sbjct: 181 TMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
>gi|206725530 FK506 binding protein 2, 13kDa precursor [Homo
sapiens]
Length = 142
Score = 92.8 bits (229), Expect = 2e-19
Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 9/120 (7%)
Query: 106 EGPPKYTKSVLKKGDKTNFP-KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
EG K V K+ D +KGDV+H YTG L+DGT FD+++ + +P F
Sbjct: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQN-------QPFVF 78
Query: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+G G+VI+GWD+ LL M +GEK +L I E YG++G P KIP A L FEVEL+ I+
Sbjct: 79 SLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAP-PKIPGGATLVFEVELLKIE 137
>gi|17149844 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 92.8 bits (229), Expect = 2e-19
Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 9/120 (7%)
Query: 106 EGPPKYTKSVLKKGDKTNFP-KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
EG K V K+ D +KGDV+H YTG L+DGT FD+++ + +P F
Sbjct: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQN-------QPFVF 78
Query: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+G G+VI+GWD+ LL M +GEK +L I E YG++G P KIP A L FEVEL+ I+
Sbjct: 79 SLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAP-PKIPGGATLVFEVELLKIE 137
>gi|17149842 FK506 binding protein 2, 13kDa precursor [Homo sapiens]
Length = 142
Score = 92.8 bits (229), Expect = 2e-19
Identities = 53/120 (44%), Positives = 72/120 (60%), Gaps = 9/120 (7%)
Query: 106 EGPPKYTKSVLKKGDKTNFP-KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
EG K V K+ D +KGDV+H YTG L+DGT FD+++ + +P F
Sbjct: 26 EGKRKLQIGVKKRVDHCPIKSRKGDVLHMHYTGKLEDGTEFDSSLPQN-------QPFVF 78
Query: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+G G+VI+GWD+ LL M +GEK +L I E YG++G P KIP A L FEVEL+ I+
Sbjct: 79 SLGTGQVIKGWDQGLLGMCEGEKRKLVIPSELGYGERGAP-PKIPGGATLVFEVELLKIE 137
>gi|4503729 FK506 binding protein 52 [Homo sapiens]
Length = 459
Score = 90.1 bits (222), Expect = 1e-18
Identities = 53/118 (44%), Positives = 66/118 (55%), Gaps = 12/118 (10%)
Query: 109 PKYTKSVLK----KGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSF 164
PK + VLK +G T P GD V YTG L DGT FD+++ K SF
Sbjct: 27 PKQDEGVLKVIKREGTGTEMPMIGDRVFVHYTGWLLDGTKFDSSLDRKDK-------FSF 79
Query: 165 KVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVD 222
+G G+VI+ WD A+ TM GE + +PE+AYG G P KIPPNA L FEVEL +
Sbjct: 80 DLGKGEVIKAWDIAIATMKVGEVCHITCKPEYAYGSAGSP-PKIPPNATLVFEVELFE 136
Score = 50.1 bits (118), Expect = 2e-06
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 16/127 (12%)
Query: 97 ETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKK 156
E K E+ +E + + +G+ P +G +V G +D K
Sbjct: 136 EFKGEDLTEEEDGGIIRRIQTRGEGYAKPNEGAIVEVALEGYYKD-------------KL 182
Query: 157 KNAKPLSFKVGVGKVIR---GWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAK 213
+ + L F++G G+ + G + A+ M KGE + + ++P +A+G G+ +IPPNA+
Sbjct: 183 FDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPSYAFGSVGKEKFQIPPNAE 242
Query: 214 LTFEVEL 220
L +E+ L
Sbjct: 243 LKYELHL 249
>gi|17149836 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 89.0 bits (219), Expect = 3e-18
Identities = 45/109 (41%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 116 LKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGW 175
+ GD FPK+G YTG L+DG FD++ + KP F +G +VIRGW
Sbjct: 8 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-------RDRNKPFKFMLGKQEVIRGW 60
Query: 176 DEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+E + MS G++A+L I P++AYG G P IPP+A L F+VEL+ ++
Sbjct: 61 EEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|4503725 FK506 binding protein 1A, 12kDa [Homo sapiens]
Length = 108
Score = 89.0 bits (219), Expect = 3e-18
Identities = 45/109 (41%), Positives = 65/109 (59%), Gaps = 8/109 (7%)
Query: 116 LKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGW 175
+ GD FPK+G YTG L+DG FD++ + KP F +G +VIRGW
Sbjct: 8 ISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSS-------RDRNKPFKFMLGKQEVIRGW 60
Query: 176 DEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+E + MS G++A+L I P++AYG G P IPP+A L F+VEL+ ++
Sbjct: 61 EEGVAQMSVGQRAKLTISPDYAYGATGHPGI-IPPHATLVFDVELLKLE 108
>gi|4758380 FK506 binding protein 1B, 12.6 kDa isoform a [Homo
sapiens]
Length = 108
Score = 84.0 bits (206), Expect = 1e-16
Identities = 44/109 (40%), Positives = 64/109 (58%), Gaps = 8/109 (7%)
Query: 116 LKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGW 175
+ GD FPKKG YTG LQ+G FD++ + KP F++G +VI+G+
Sbjct: 8 ISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-------RDRNKPFKFRIGKQEVIKGF 60
Query: 176 DEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID 224
+E MS G++A+L P+ AYG G P IPPNA L F+VEL++++
Sbjct: 61 EEGAAQMSLGQRAKLTCTPDVAYGATGHPGV-IPPNATLIFDVELLNLE 108
>gi|224809331 FK506 binding protein 5 isoform 2 [Homo sapiens]
Length = 268
Score = 80.9 bits (198), Expect = 8e-16
Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)
Query: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142
+ K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
Query: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202
FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G
Sbjct: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
Query: 203 QPDAKIPPNAKLTFEVELVD 222
KIP NA L FE+EL+D
Sbjct: 118 SL-PKIPSNATLFFEIELLD 136
>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 80.9 bits (198), Expect = 8e-16
Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)
Query: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142
+ K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
Query: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202
FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G
Sbjct: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
Query: 203 QPDAKIPPNAKLTFEVELVD 222
KIP NA L FE+EL+D
Sbjct: 118 SL-PKIPSNATLFFEIELLD 136
Score = 45.1 bits (105), Expect = 5e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 99 KSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKN 158
K E+ ++G + +KG+ + P +G V G G +FD
Sbjct: 138 KGEDLFEDGG--IIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------ 182
Query: 159 AKPLSFKVGVGK---VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLT 215
+ ++F VG G+ + G D+AL M + E+ L + P + +G+ G+P I PNA+L
Sbjct: 183 CRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242
Query: 216 FEVEL 220
+EV L
Sbjct: 243 YEVTL 247
>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 80.9 bits (198), Expect = 8e-16
Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)
Query: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142
+ K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
Query: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202
FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G
Sbjct: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
Query: 203 QPDAKIPPNAKLTFEVELVD 222
KIP NA L FE+EL+D
Sbjct: 118 SL-PKIPSNATLFFEIELLD 136
Score = 45.1 bits (105), Expect = 5e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 99 KSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKN 158
K E+ ++G + +KG+ + P +G V G G +FD
Sbjct: 138 KGEDLFEDGG--IIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------ 182
Query: 159 AKPLSFKVGVGK---VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLT 215
+ ++F VG G+ + G D+AL M + E+ L + P + +G+ G+P I PNA+L
Sbjct: 183 CRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242
Query: 216 FEVEL 220
+EV L
Sbjct: 243 YEVTL 247
>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
Length = 457
Score = 80.9 bits (198), Expect = 8e-16
Identities = 52/140 (37%), Positives = 72/140 (51%), Gaps = 11/140 (7%)
Query: 86 KNVKLNEDKPKETKSEETLDEGPPK---YTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDG 142
+ K NE+ P T +E+ D K K V + G+ P GD V+ Y G L +G
Sbjct: 5 EGAKNNEESPTATVAEQGEDITSKKDRGVLKIVKRVGNGEETPMIGDKVYVHYKGKLSNG 64
Query: 143 TVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKG 202
FD++ + +P F +G G+VI+ WD + TM KGE L +PE+AYG G
Sbjct: 65 KKFDSSHDRN-------EPFVFSLGKGQVIKAWDIGVATMKKGEICHLLCKPEYAYGSAG 117
Query: 203 QPDAKIPPNAKLTFEVELVD 222
KIP NA L FE+EL+D
Sbjct: 118 SL-PKIPSNATLFFEIELLD 136
Score = 45.1 bits (105), Expect = 5e-05
Identities = 35/125 (28%), Positives = 59/125 (47%), Gaps = 18/125 (14%)
Query: 99 KSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKN 158
K E+ ++G + +KG+ + P +G V G G +FD
Sbjct: 138 KGEDLFEDGG--IIRRTKRKGEGYSNPNEGATVEIHLEGRC-GGRMFD------------ 182
Query: 159 AKPLSFKVGVGK---VIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLT 215
+ ++F VG G+ + G D+AL M + E+ L + P + +G+ G+P I PNA+L
Sbjct: 183 CRDVAFTVGEGEDHDIPIGIDKALEKMQREEQCILYLGPRYGFGEAGKPKFGIEPNAELI 242
Query: 216 FEVEL 220
+EV L
Sbjct: 243 YEVTL 247
>gi|31317231 FK506 binding protein 7 isoform a precursor [Homo
sapiens]
Length = 222
Score = 75.1 bits (183), Expect = 5e-14
Identities = 41/96 (42%), Positives = 60/96 (62%), Gaps = 6/96 (6%)
Query: 126 KKGDVVHCWYTGTL-QDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSK 184
KKGD+++ Y G L +DG+ F ++ + P F +GVG+VI+G D A+ M
Sbjct: 51 KKGDLLNAHYDGYLAKDGSKF-----YCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCP 105
Query: 185 GEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
GEK ++ I P +AYGK+G + KIPP+A L FE+EL
Sbjct: 106 GEKRKVVIPPSFAYGKEGYAEGKIPPDATLIFEIEL 141
>gi|206725547 FK506 binding protein 7 isoform b precursor [Homo
sapiens]
Length = 221
Score = 70.9 bits (172), Expect = 9e-13
Identities = 41/96 (42%), Positives = 60/96 (62%), Gaps = 7/96 (7%)
Query: 126 KKGDVVHCWYTGTL-QDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSK 184
KKGD+++ Y G L +DG+ F ++ + P F +GVG+VI+G D A+ M
Sbjct: 51 KKGDLLNAHYDGYLAKDGSKF-----YCSRTQNEGHPKWFVLGVGQVIKGLDIAMTDMCP 105
Query: 185 GEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
GEK ++ I P +AYGK+G + KIPP+A L FE+EL
Sbjct: 106 GEKRKVVIPPSFAYGKEGY-EGKIPPDATLIFEIEL 140
>gi|8923659 FK506 binding protein 14 [Homo sapiens]
Length = 211
Score = 68.9 bits (167), Expect = 3e-12
Identities = 38/99 (38%), Positives = 59/99 (59%), Gaps = 8/99 (8%)
Query: 126 KKGDVVHCWYTGTLQ-DGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSK 184
K GD++ Y G L+ DG++F S K N +P+ F +G+ + ++GWD+ L M
Sbjct: 43 KGGDLMLVHYEGYLEKDGSLFH-----STHKHNNGQPIWFTLGILEALKGWDQGLKGMCV 97
Query: 185 GEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
GEK +L I P YGK+G+ KIPP + L F ++L++I
Sbjct: 98 GEKRKLIIPPALGYGKEGK--GKIPPESTLIFNIDLLEI 134
>gi|192448443 FK506 binding protein 10 [Homo sapiens]
Length = 582
Score = 65.5 bits (158), Expect = 4e-11
Identities = 40/96 (41%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
GD V Y GTL DGT FDT+ VG G +I+G D+ LL M GE+
Sbjct: 174 GDFVRYHYNGTLLDGTSFDTSYSKGGT-------YDTYVGSGWLIKGMDQGLLGMCPGER 226
Query: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
++ I P AYG+KG IPP A L F V L+D+
Sbjct: 227 RKIIIPPFLAYGEKGY-GTVIPPQASLVFHVLLIDV 261
Score = 59.3 bits (142), Expect = 3e-09
Identities = 35/96 (36%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
GD V Y GT +DG FD++ + ++ VGVG++I G D L+ M E+
Sbjct: 62 GDFVRYHYNGTFEDGKKFDSSYDRNTL-------VAIVVGVGRLITGMDRGLMGMCVNER 114
Query: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
RL + P YG G IPP+A L F+V L+D+
Sbjct: 115 RRLIVPPHLGYGSIGLA-GLIPPDATLYFDVVLLDV 149
Score = 58.5 bits (140), Expect = 4e-09
Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 8/95 (8%)
Query: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
GD + Y G+L DGT+FD++ + + +G G +I G D+ L GE+
Sbjct: 286 GDFMRYHYNGSLMDGTLFDSSYSRN-------HTYNTYIGQGYIIPGMDQGLQGACMGER 338
Query: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVD 222
R+ I P AYG+ G D KIP +A L F V ++D
Sbjct: 339 RRITIPPHLAYGENGTGD-KIPGSAVLIFNVHVID 372
Score = 50.1 bits (118), Expect = 2e-06
Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 9/96 (9%)
Query: 126 KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKG 185
K GD V Y +L DGT T+ A P +G KVI G D L M G
Sbjct: 397 KLGDFVRYHYNCSLLDGTQLFTSHDYGA-------PQEATLGANKVIEGLDTGLQGMCVG 449
Query: 186 EKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELV 221
E+ +L + P A+G+ G +P +A L FEVELV
Sbjct: 450 ERRQLIVPPHLAHGESGA--RGVPGSAVLLFEVELV 483
>gi|7706131 FK506 binding protein 11 isoform 1 precursor [Homo
sapiens]
Length = 201
Score = 65.5 bits (158), Expect = 4e-11
Identities = 44/132 (33%), Positives = 65/132 (49%), Gaps = 19/132 (14%)
Query: 90 LNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNI 149
L + P T ETL E P + GD +H YTG+L DG + DT++
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAF----------GDTLHIHYTGSLVDGRIIDTSL 78
Query: 150 QTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIP 209
PL ++G +VI G +++LL M GEK R I AYGK+G P + +P
Sbjct: 79 TRD--------PLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFPPS-VP 129
Query: 210 PNAKLTFEVELV 221
+A + ++VEL+
Sbjct: 130 ADAVVQYDVELI 141
>gi|33469985 FK506 binding protein 9 [Homo sapiens]
Length = 570
Score = 62.4 bits (150), Expect = 3e-10
Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 12/122 (9%)
Query: 104 LDEGPPKYTKSVLKKGDKTN---FPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAK 160
LD PK + S+ K N + GD + Y GTL DGT+FD++ + +
Sbjct: 251 LDLHNPKDSISIENKVVPENCERISQSGDFLRYHYNGTLLDGTLFDSSYSRN-------R 303
Query: 161 PLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
+G G VI G DE LL + GEK R+ + P YG++G+ IP +A L F++ +
Sbjct: 304 TFDTYIGQGYVIPGMDEGLLGVCIGEKRRIVVPPHLGYGEEGR--GNIPGSAVLVFDIHV 361
Query: 221 VD 222
+D
Sbjct: 362 ID 363
Score = 59.3 bits (142), Expect = 3e-09
Identities = 36/98 (36%), Positives = 53/98 (54%), Gaps = 8/98 (8%)
Query: 126 KKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKG 185
+ GD V Y GT DG FD++ + + VG G++I G D+AL+ M
Sbjct: 52 RSGDFVRYHYVGTFPDGQKFDSSYDRDST-------FNVFVGKGQLITGMDQALVGMCVN 104
Query: 186 EKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
E+ ++I P+ AYG +G IPPN+ L F+V L+DI
Sbjct: 105 ERRFVKIPPKLAYGNEG-VSGVIPPNSVLHFDVLLMDI 141
Score = 58.2 bits (139), Expect = 6e-09
Identities = 39/96 (40%), Positives = 50/96 (52%), Gaps = 10/96 (10%)
Query: 129 DVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKA 188
D V Y GT DGT+FD++ K VG+G +I G D+ LL M GEK
Sbjct: 167 DFVRYHYNGTFLDGTLFDSS-------HNRMKTYDTYVGIGWLIPGMDKGLLGMCVGEKR 219
Query: 189 RLEIEPEWAYGKKGQPDAK-IPPNAKLTFEVELVDI 223
+ I P AYG+ G D K IP A L F+V L+D+
Sbjct: 220 IITIPPFLAYGEDG--DGKDIPGQASLVFDVALLDL 253
Score = 56.6 bits (135), Expect = 2e-08
Identities = 35/107 (32%), Positives = 54/107 (50%), Gaps = 8/107 (7%)
Query: 117 KKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWD 176
K D + KKGD + Y +L DGT+ D+ K + +G G+V+ G D
Sbjct: 378 KPPDCSVLSKKGDYLKYHYNASLLDGTLLDSTWNLG-------KTYNIVLGSGQVVLGMD 430
Query: 177 EALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDI 223
L M GEK + I P YG+ G D ++P +A L F++EL+++
Sbjct: 431 MGLREMCVGEKRTVIIPPHLGYGEAG-VDGEVPGSAVLVFDIELLEL 476
>gi|219842220 FK506 binding protein 11 isoform 3 precursor [Homo
sapiens]
Length = 146
Score = 57.4 bits (137), Expect = 1e-08
Identities = 39/115 (33%), Positives = 53/115 (46%), Gaps = 18/115 (15%)
Query: 90 LNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNI 149
L + P T ETL E P + GD +H YTG+L DG + DT++
Sbjct: 29 LETESPVRTLQVETLVEPPEPCAEPAAF----------GDTLHIHYTGSLVDGRIIDTSL 78
Query: 150 QTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQP 204
PL ++G +VI G +++LL M GEK R I AYGK+G P
Sbjct: 79 TRD--------PLVIELGQKQVIPGLEQSLLDMCVGEKRRAIIPSHLAYGKRGFP 125
>gi|150010552 FK506 binding protein 15, 133kDa [Homo sapiens]
Length = 1219
Score = 53.1 bits (126), Expect = 2e-07
Identities = 34/93 (36%), Positives = 47/93 (50%), Gaps = 3/93 (3%)
Query: 128 GDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEK 187
GD + YTG L V ++A K K L K+G GKVI+GW++ +L M KG K
Sbjct: 197 GDSLEVAYTGWLFQNHVLGQVFDSTANKDKL---LRLKLGSGKVIKGWEDGMLGMKKGGK 253
Query: 188 ARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
L + P A G +G ++ L FEVE+
Sbjct: 254 RLLIVPPACAVGSEGVIGWTQATDSILVFEVEV 286
>gi|206725544 FK506 binding protein 6 isoform b [Homo sapiens]
Length = 322
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 161 PLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
P K+G + G + LL+M +GE AR +P +AYG G P IPPN + FE+EL
Sbjct: 76 PRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIEL 134
Query: 221 VD 222
+D
Sbjct: 135 LD 136
>gi|146229346 FK506 binding protein 6 isoform a [Homo sapiens]
Length = 327
Score = 48.9 bits (115), Expect = 3e-06
Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Query: 161 PLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
P K+G + G + LL+M +GE AR +P +AYG G P IPPN + FE+EL
Sbjct: 81 PRLMKLGEDITLWGMELGLLSMRRGELARFLFKPNYAYGTLGCPPL-IPPNTTVLFEIEL 139
Query: 221 VD 222
+D
Sbjct: 140 LD 141
>gi|17149839 FK506 binding protein 1B, 12.6 kDa isoform b [Homo
sapiens]
Length = 80
Score = 45.8 bits (107), Expect = 3e-05
Identities = 23/62 (37%), Positives = 34/62 (54%), Gaps = 7/62 (11%)
Query: 116 LKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGW 175
+ GD FPKKG YTG LQ+G FD++ + KP F++G +VI+G+
Sbjct: 8 ISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSS-------RDRNKPFKFRIGKQEVIKGF 60
Query: 176 DE 177
+E
Sbjct: 61 EE 62
>gi|118498337 HECT domain containing 1 [Homo sapiens]
Length = 2610
Score = 45.1 bits (105), Expect = 5e-05
Identities = 22/63 (34%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Query: 10 WTVEQ----LRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNH 65
W++E L +++LPK D+I +LQ++ +FL KL G K++ K N L+ AY
Sbjct: 1894 WSIEHVEQYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKD 1953
Query: 66 LFE 68
E
Sbjct: 1954 FCE 1956
>gi|52630440 FK506-binding protein 8 [Homo sapiens]
Length = 413
Score = 42.7 bits (99), Expect = 2e-04
Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 22/120 (18%)
Query: 101 EETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAK 160
++TL GPP ++ P KG VV +L++GT + +
Sbjct: 104 KKTLVPGPPGSSR-----------PVKGQVVTVHLQTSLENGT-----------RVQEEP 141
Query: 161 PLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVEL 220
L F +G VI+ D ++ M GE A + + ++ YG +G IPP+A L EV L
Sbjct: 142 ELVFTLGDCDVIQALDLSVPLMDVGETAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 201
>gi|53759134 endonuclease G precursor [Homo sapiens]
Length = 297
Score = 34.3 bits (77), Expect = 0.089
Identities = 25/82 (30%), Positives = 35/82 (42%), Gaps = 1/82 (1%)
Query: 10 WTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFET 69
W VEQLR E+L + DS A H+ N ++ HL A NH +
Sbjct: 94 WVVEQLRPERLRGDGDRRECDFREDDSVHAYHRAT-NADYRGSGFDRGHLAAAANHRWSQ 152
Query: 70 KRFKGTESISKVSEQVKNVKLN 91
K T +S V+ QV ++ N
Sbjct: 153 KAMDDTFYLSNVAPQVPHLNQN 174
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 34.3 bits (77), Expect = 0.089
Identities = 41/120 (34%), Positives = 57/120 (47%), Gaps = 18/120 (15%)
Query: 7 QRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHL 66
++A EQ R++QL +K +QE E K+ G N K A +D L TA
Sbjct: 379 EKAKVEEQKRNKQLEEKK--HAMQETKIKGEKVEQKIEGKWVN-EKKAQEDKLQTA---- 431
Query: 67 FETKRFKGTESISKVSEQVKNVKLNEDKP---KETKSEETL--DEGPPKYTKSVL--KKG 119
+ +G E +KV Q K KL EDKP KE +E + D+ P + KS + KKG
Sbjct: 432 --VLKKQGEEKGTKV--QAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKG 487
>gi|219842217 FK506 binding protein 11 isoform 2 [Homo sapiens]
Length = 99
Score = 32.7 bits (73), Expect = 0.26
Identities = 17/40 (42%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 182 MSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELV 221
M GEK R I AYGK+G P + +P +A + ++VEL+
Sbjct: 1 MCVGEKRRAIIPSHLAYGKRGFPPS-VPADAVVQYDVELI 39
>gi|42518068 trans-golgi network protein 2 [Homo sapiens]
Length = 437
Score = 32.7 bits (73), Expect = 0.26
Identities = 20/52 (38%), Positives = 31/52 (59%), Gaps = 3/52 (5%)
Query: 65 HLFETKRFKGTESISKVSEQVKNVKLNED-KPKETKSEETLDE--GPPKYTK 113
H F+T+ + T+ IS E+VK+ + ED +PKE + ++T E PPK K
Sbjct: 292 HAFKTESGEETDLISPPQEEVKSSEPTEDVEPKEAEDDDTGPEEGSPPKEEK 343
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 30.4 bits (67), Expect = 1.3
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 9/47 (19%)
Query: 76 ESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKT 122
E +S E KN LN+DK LDE PK + +LK+ D+T
Sbjct: 713 EELSLKDELEKNENLNDDK---------LDEENPKISAHILKENDRT 750
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.130 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,360,240
Number of Sequences: 37866
Number of extensions: 347046
Number of successful extensions: 1054
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 976
Number of HSP's gapped (non-prelim): 64
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.