Search of human proteins with 4503529

Search of human proteins with 4503529

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503529 eukaryotic translation initiation factor 4A isoform
1 [Homo sapiens]
         (406 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503529 eukaryotic translation initiation factor 4A isoform 1...   799   0.0  
gi|83700235 eukaryotic translation initiation factor 4A2 [Homo s...   736   0.0  
gi|7661920 eukaryotic translation initiation factor 4A, isoform ...   540   e-154
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi...   277   1e-74
gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [H...   270   1e-72
gi|8922886 DDX19-like protein [Homo sapiens]                          268   7e-72
gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo sap...   264   1e-70
gi|4758112 HLA-B associated transcript 1 [Homo sapiens]               255   6e-68
gi|18375623 HLA-B associated transcript 1 [Homo sapiens]              255   6e-68
gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo sapi...   254   1e-67
gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3 [...   251   8e-67
gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2 [...   243   2e-64
gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo sapi...   242   5e-64
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap...   210   2e-54
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...   203   2e-52
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ...   203   3e-52
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ...   202   4e-52
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [...   202   4e-52
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...   200   2e-51
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap...   199   3e-51
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo...   197   1e-50
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap...   196   4e-50
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]         195   5e-50
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]          195   5e-50
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ...   195   7e-50
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1...   195   7e-50
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]    193   2e-49
gi|21071032 DEAD-box protein abstrakt [Homo sapiens]                  187   1e-47
gi|13129006 nucleolar protein GU2 [Homo sapiens]                      185   6e-47
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi...   184   1e-46

>gi|4503529 eukaryotic translation initiation factor 4A isoform 1
           [Homo sapiens]
          Length = 406

 Score =  799 bits (2064), Expect = 0.0
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 1   MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60
           MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ
Sbjct: 1   MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60

Query: 61  RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120
           RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV
Sbjct: 61  RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120

Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180
           MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV
Sbjct: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180

Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240
           LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE
Sbjct: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240

Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300
           LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS
Sbjct: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300

Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360
           AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI
Sbjct: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360

Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
           GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI
Sbjct: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406


>gi|83700235 eukaryotic translation initiation factor 4A2 [Homo
           sapiens]
          Length = 407

 Score =  736 bits (1901), Expect = 0.0
 Identities = 364/403 (90%), Positives = 388/403 (96%)

Query: 4   SQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAI 63
           S D      GP+GM+P+GVIESNWNEIVD+FDDMNL ESLLRGIYAYGFEKPSAIQQRAI
Sbjct: 5   SADYNREHGGPEGMDPDGVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAI 64

Query: 64  LPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMAL 123
           +PCIKGYDVIAQAQSGTGKTATFAISILQQ+E++ K TQALVLAPTRELAQQIQKV++AL
Sbjct: 65  IPCIKGYDVIAQAQSGTGKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILAL 124

Query: 124 GDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDE 183
           GDYMGA+CHACIGGTNVR E+QKLQ EAPHI+VGTPGRVFDMLNRRYLSPK+IKMFVLDE
Sbjct: 125 GDYMGATCHACIGGTNVRNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDE 184

Query: 184 ADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTL 243
           ADEMLSRGFKDQIY+IFQKLN++ QVVLLSATMP+DVLEVTKKFMRDPIRILVKKEELTL
Sbjct: 185 ADEMLSRGFKDQIYEIFQKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKEELTL 244

Query: 244 EGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMH 303
           EGI+QFYINVEREEWKLDTLCDLYETLTITQAVIF+NTRRKVDWLTEKMHARDFTVSA+H
Sbjct: 245 EGIKQFYINVEREEWKLDTLCDLYETLTITQAVIFLNTRRKVDWLTEKMHARDFTVSALH 304

Query: 304 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 363
           GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG
Sbjct: 305 GDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRG 364

Query: 364 GRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
           GRFGRKGVAIN VTEEDKR LRDIETFYNT++EEMP+NVADLI
Sbjct: 365 GRFGRKGVAINFVTEEDKRILRDIETFYNTTVEEMPMNVADLI 407


>gi|7661920 eukaryotic translation initiation factor 4A, isoform 3
           [Homo sapiens]
          Length = 411

 Score =  540 bits (1391), Expect = e-154
 Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%)

Query: 1   MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 60
           M+ S  +R R    + M       S   ++  +FD M L E LLRGIYAYGFEKPSAIQQ
Sbjct: 7   MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66

Query: 61  RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 120
           RAI   IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK +
Sbjct: 67  RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126

Query: 121 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 180
           +ALGDYM   CHACIGGTNV  +++KL     H++ GTPGRVFDM+ RR L  + IKM V
Sbjct: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185

Query: 181 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 240
           LDEADEML++GFK+QIYD+++ L   TQVVL+SAT+P ++LE+T KFM DPIRILVK++E
Sbjct: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245

Query: 241 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 300
           LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM   +FTVS
Sbjct: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305

Query: 301 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 360
           +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI
Sbjct: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365

Query: 361 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
           GR GR+GRKGVAIN V  +D R LRDIE +Y+T I+EMP+NVADLI
Sbjct: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411


>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
           sapiens]
          Length = 483

 Score =  277 bits (708), Expect = 1e-74
 Identities = 144/372 (38%), Positives = 232/372 (62%), Gaps = 4/372 (1%)

Query: 32  DSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISIL 91
           + F+D  L   LL GI+  G+EKPS IQ+ +I   + G D++A+A++GTGK+  + I +L
Sbjct: 96  NEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLL 155

Query: 92  QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMG-ASCHACIGGTNVRAEVQKLQME 150
           ++++L     QA+V+ PTRELA Q+ ++ + +  +MG A   A  GGTN+R ++ +L  +
Sbjct: 156 ERLDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLD-D 214

Query: 151 APHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVV 210
             H+++ TPGR+ D++ +      +++M VLDEAD++LS+ F   + DI   L  N Q++
Sbjct: 215 TVHVVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQIL 274

Query: 211 LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETL 270
           L SAT P  V +     ++ P  I +  EELTL+G+ Q+Y  V  E  K+  L  L+  L
Sbjct: 275 LYSATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRL 332

Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330
            I Q++IF N+ ++V+ L +K+    ++   +H  M Q+ R+ +  +FR+G  R L+ TD
Sbjct: 333 QINQSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTD 392

Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETF 390
           L  RGID+Q V++VIN+D P   E Y+HRIGR GRFG  G+AIN++T +D+  L+ IE  
Sbjct: 393 LFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQ 452

Query: 391 YNTSIEEMPLNV 402
             T I+ +P N+
Sbjct: 453 LGTEIKPIPSNI 464


>gi|6005743 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 1 [Homo
           sapiens]
          Length = 479

 Score =  270 bits (691), Expect = 1e-72
 Identities = 157/388 (40%), Positives = 237/388 (61%), Gaps = 16/388 (4%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFA 87
           V SF+++ L   LL+G+YA GF +PS IQ+ A LP +      ++IAQ+QSGTGKTA F 
Sbjct: 91  VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFV 149

Query: 88  ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147
           +++L Q+E   K  Q L L+PT ELA Q  KV+  +G +      A     N     QK+
Sbjct: 150 LAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 209

Query: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNS 205
             +   I++GTPG V D  ++ +++ PK IK+FVLDEAD M++ +G +DQ   I + L  
Sbjct: 210 SEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 266

Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
           N Q++L SAT    V +  +K + DP  I +K+EE TL+ I+Q+Y+     + K   LC+
Sbjct: 267 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCN 326

Query: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325
           LY  +TI QA+IF +TR+   WL  ++      V+ + G+M  ++R  ++  FR G  +V
Sbjct: 327 LYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKV 386

Query: 326 LITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TE 378
           L+TT++ ARGIDV+QVS+VIN+DLP ++      E Y+HRIGR GRFG++G+A+NMV ++
Sbjct: 387 LVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 446

Query: 379 EDKRTLRDIETFYNTSIEEMPLNVADLI 406
                L  I+  +N  IE +  +  D I
Sbjct: 447 HSMNILNRIQEHFNKKIERLDTDDLDEI 474


>gi|8922886 DDX19-like protein [Homo sapiens]
          Length = 478

 Score =  268 bits (685), Expect = 7e-72
 Identities = 155/388 (39%), Positives = 237/388 (61%), Gaps = 16/388 (4%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFA 87
           V SF+++ L   LL+G+YA GF +PS IQ+ A LP +      ++IAQ+QSGTGKTA F 
Sbjct: 90  VKSFEELRLKPQLLQGVYAMGFNRPSKIQENA-LPMMLAEPPQNLIAQSQSGTGKTAAFV 148

Query: 88  ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKL 147
           +++L ++E   +  Q L L+PT ELA Q  KV+  +G +      A     N     QK+
Sbjct: 149 LAMLSRVEPSDRYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI 208

Query: 148 QMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNS 205
             +   I++GTPG V D  ++ +++ PK IK+FVLDEAD M++ +G +DQ   I + L  
Sbjct: 209 SEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPR 265

Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
           N Q++L SAT    V +  +K + DP  I +K+EE TL+ I+Q+Y+     + K   LC+
Sbjct: 266 NCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCN 325

Query: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRV 325
           LY  +TI QA+IF +TR+   WL  ++      V+ + G+M  ++R  ++  FR G  +V
Sbjct: 326 LYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKV 385

Query: 326 LITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TE 378
           L+TT++ ARGIDV+QVS+VIN+DLP ++      E Y+HRIGR GRFG++G+A+NMV ++
Sbjct: 386 LVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSK 445

Query: 379 EDKRTLRDIETFYNTSIEEMPLNVADLI 406
                L  I+  +N  IE +  +  D I
Sbjct: 446 HSMNILNRIQEHFNKKIERLDTDDLDEI 473


>gi|164419732 DEAD (Asp-Glu-Ala-Asp) box polypeptide 25 [Homo
           sapiens]
          Length = 483

 Score =  264 bits (674), Expect = 1e-70
 Identities = 157/387 (40%), Positives = 235/387 (60%), Gaps = 19/387 (4%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY---DVIAQAQSGTGKTATFA 87
           V +F+++ L E LL+GIYA GF +PS IQ+ A LP +  +   ++IAQ+QSGTGKTA F 
Sbjct: 96  VKTFEELRLKEELLKGIYAMGFNRPSKIQEMA-LPMMLAHPPQNLIAQSQSGTGKTAAFV 154

Query: 88  ISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDY-MGASCHACIGGTNVRAEVQK 146
           +++L ++       Q L LAPT ELA Q  +VV  +G + +       I G  +      
Sbjct: 155 LAMLSRVNALELFPQCLCLAPTYELALQTGRVVEQMGKFCVDVQVMYAIRGNRIPRGTDI 214

Query: 147 LQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEML-SRGFKDQIYDIFQKLN 204
            +     II+GTPG V D   + + +    I++FVLDEAD M+ ++GF D    I + L 
Sbjct: 215 TKQ----IIIGTPGTVLDWCFKLKLIDLTKIRVFVLDEADVMIDTQGFSDHSIRIQRALP 270

Query: 205 SNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLC 264
           S  Q++L SAT    V    ++ + DP  I ++KEELTL  IRQ+Y+  E  + K   LC
Sbjct: 271 SECQMLLFSATFEDSVWHFAERIIPDPNVIKLRKEELTLNNIRQYYVLCEHRKDKYQALC 330

Query: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324
           ++Y ++TI QA+IF  TRR   WLT +M      VS + G++  ++R  I++ FR G  +
Sbjct: 331 NIYGSITIGQAIIFCQTRRNAKWLTVEMIQDGHQVSLLSGELTVEQRASIIQRFRDGKEK 390

Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGRGGRFGRKGVAINMVTE 378
           VLITT++ ARGIDV+QV++V+N+DLP  +      E Y+HRIGR GRFG+KG+A NM+  
Sbjct: 391 VLITTNVCARGIDVKQVTIVVNFDLPVKQGEEPDYETYLHRIGRTGRFGKKGLAFNMIEV 450

Query: 379 EDKRTLRDIETFYNTSIEEMPLNVADL 405
           ++  +L  I+  +N+SI++  LN  D+
Sbjct: 451 DELPSLMKIQDHFNSSIKQ--LNAEDM 475


>gi|4758112 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  255 bits (651), Expect = 6e-68
 Identities = 139/370 (37%), Positives = 217/370 (58%), Gaps = 5/370 (1%)

Query: 34  FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93
           F D  L   LLR I   GFE PS +Q   I   I G DV+ QA+SG GKTA F ++ LQQ
Sbjct: 47  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106

Query: 94  IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152
           +E        LV+  TRELA QI K       YM         GG +++ + + L+   P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166

Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211
           HI+VGTPGR+  +   + L+ K+IK F+LDE D+ML +   +  + +IF+      QV++
Sbjct: 167 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 226

Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETL 270
            SAT+  ++  V +KFM+DP+ I V  E +LTL G++Q+Y+ ++  E K   L DL + L
Sbjct: 227 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 285

Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330
              Q VIF+ + ++   L + +  ++F   A+H  M Q+ER    ++F+    R+L+ T+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345

Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIET 389
           L  RG+D+++V++  NYD+P + + Y+HR+ R GRFG KG+AI  V++E D + L D++ 
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405

Query: 390 FYNTSIEEMP 399
            +  +I E+P
Sbjct: 406 RFEVNISELP 415


>gi|18375623 HLA-B associated transcript 1 [Homo sapiens]
          Length = 428

 Score =  255 bits (651), Expect = 6e-68
 Identities = 139/370 (37%), Positives = 217/370 (58%), Gaps = 5/370 (1%)

Query: 34  FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93
           F D  L   LLR I   GFE PS +Q   I   I G DV+ QA+SG GKTA F ++ LQQ
Sbjct: 47  FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 106

Query: 94  IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152
           +E        LV+  TRELA QI K       YM         GG +++ + + L+   P
Sbjct: 107 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 166

Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQIYDIFQKLNSNTQVVL 211
           HI+VGTPGR+  +   + L+ K+IK F+LDE D+ML +   +  + +IF+      QV++
Sbjct: 167 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 226

Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVEREEWKLDTLCDLYETL 270
            SAT+  ++  V +KFM+DP+ I V  E +LTL G++Q+Y+ ++  E K   L DL + L
Sbjct: 227 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 285

Query: 271 TITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTD 330
              Q VIF+ + ++   L + +  ++F   A+H  M Q+ER    ++F+    R+L+ T+
Sbjct: 286 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 345

Query: 331 LLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEE-DKRTLRDIET 389
           L  RG+D+++V++  NYD+P + + Y+HR+ R GRFG KG+AI  V++E D + L D++ 
Sbjct: 346 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 405

Query: 390 FYNTSIEEMP 399
            +  +I E+P
Sbjct: 406 RFEVNISELP 415


>gi|21040371 DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 [Homo
           sapiens]
          Length = 427

 Score =  254 bits (648), Expect = 1e-67
 Identities = 142/386 (36%), Positives = 224/386 (58%), Gaps = 6/386 (1%)

Query: 19  PEGVIESNWNEIVDS-FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQ 77
           P+  I+ ++  I  S F D  L   LLR I   GFE PS +Q   I   I G DV+ QA+
Sbjct: 30  PKKDIKGSYVSIHSSGFRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAK 89

Query: 78  SGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIG 136
           SG GKTA F ++ LQQIE        LV+  TRELA QI K       YM         G
Sbjct: 90  SGMGKTAVFVLATLQQIEPVNGQVTVLVMCHTRELAFQISKEYERFSKYMPSVKVSVFFG 149

Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSR-GFKDQ 195
           G +++ + + L+   PH++VGTPGR+  ++  R  S K +K FVLDE D+ML +   +  
Sbjct: 150 GLSIKKDEEVLKKNCPHVVVGTPGRILALVRNRSFSLKNVKHFVLDECDKMLEQLDMRRD 209

Query: 196 IYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVE 254
           + +IF+      Q ++ SAT+  D+  V +KFM+DP+ + V  E +LTL G++Q+Y+ ++
Sbjct: 210 VQEIFRLTPHEKQCMMFSATLSKDIRPVCRKFMQDPMEVFVDDETKLTLHGLQQYYVKLK 269

Query: 255 REEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVI 314
             E K   L DL + L   Q +IF+ + ++   L + +  ++F   A+H  M Q+ER   
Sbjct: 270 DSE-KNRKLFDLLDVLEFNQVIIFVKSVQRCMALAQLLVEQNFPAIAIHRGMAQEERLSR 328

Query: 315 MREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAIN 374
            ++F+    R+L+ T+L  RG+D+++V++V NYD+P + + Y+HR+ R GRFG KG+AI 
Sbjct: 329 YQQFKDFQRRILVATNLFGRGMDIERVNIVFNYDMPEDSDTYLHRVARAGRFGTKGLAIT 388

Query: 375 MVTEE-DKRTLRDIETFYNTSIEEMP 399
            V++E D + L D++  +  ++ E+P
Sbjct: 389 FVSDENDAKILNDVQDRFEVNVAELP 414


>gi|62241022 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 3
           [Homo sapiens]
          Length = 370

 Score =  251 bits (641), Expect = 8e-67
 Identities = 148/368 (40%), Positives = 223/368 (60%), Gaps = 16/368 (4%)

Query: 51  GFEKPSAIQQRAILPCIKG---YDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLA 107
           GF +PS IQ+ A LP +      ++IAQ+QSGTGKTA F +++L Q+E   K  Q L L+
Sbjct: 2   GFNRPSKIQENA-LPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLS 60

Query: 108 PTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLN 167
           PT ELA Q  KV+  +G +      A     N     QK+  +   I++GTPG V D  +
Sbjct: 61  PTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCS 117

Query: 168 R-RYLSPKYIKMFVLDEADEMLS-RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTK 225
           + +++ PK IK+FVLDEAD M++ +G +DQ   I + L  N Q++L SAT    V +  +
Sbjct: 118 KLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQ 177

Query: 226 KFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKV 285
           K + DP  I +K+EE TL+ I+Q+Y+     + K   LC+LY  +TI QA+IF +TR+  
Sbjct: 178 KVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTA 237

Query: 286 DWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVI 345
            WL  ++      V+ + G+M  ++R  ++  FR G  +VL+TT++ ARGIDV+QVS+VI
Sbjct: 238 SWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVI 297

Query: 346 NYDLPTNR------ENYIHRIGRGGRFGRKGVAINMV-TEEDKRTLRDIETFYNTSIEEM 398
           N+DLP ++      E Y+HRIGR GRFG++G+A+NMV ++     L  I+  +N  IE +
Sbjct: 298 NFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERL 357

Query: 399 PLNVADLI 406
             +  D I
Sbjct: 358 DTDDLDEI 365


>gi|62241024 DEAD (Asp-Glu-Ala-As) box polypeptide 19 isoform 2
           [Homo sapiens]
          Length = 448

 Score =  243 bits (620), Expect = 2e-64
 Identities = 139/345 (40%), Positives = 211/345 (61%), Gaps = 12/345 (3%)

Query: 71  DVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130
           ++IAQ+QSGTGKTA F +++L Q+E   K  Q L L+PT ELA Q  KV+  +G +    
Sbjct: 102 NLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPEL 161

Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNR-RYLSPKYIKMFVLDEADEMLS 189
             A     N     QK+  +   I++GTPG V D  ++ +++ PK IK+FVLDEAD M++
Sbjct: 162 KLAYAVRGNKLERGQKISEQ---IVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIA 218

Query: 190 -RGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248
            +G +DQ   I + L  N Q++L SAT    V +  +K + DP  I +K+EE TL+ I+Q
Sbjct: 219 TQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQ 278

Query: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308
           +Y+     + K   LC+LY  +TI QA+IF +TR+   WL  ++      V+ + G+M  
Sbjct: 279 YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMV 338

Query: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNR------ENYIHRIGR 362
           ++R  ++  FR G  +VL+TT++ ARGIDV+QVS+VIN+DLP ++      E Y+HRIGR
Sbjct: 339 EQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGR 398

Query: 363 GGRFGRKGVAINMV-TEEDKRTLRDIETFYNTSIEEMPLNVADLI 406
            GRFG++G+A+NMV ++     L  I+  +N  IE +  +  D I
Sbjct: 399 TGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTDDLDEI 443


>gi|14251212 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 [Homo
           sapiens]
          Length = 824

 Score =  242 bits (617), Expect = 5e-64
 Identities = 138/363 (38%), Positives = 216/363 (59%), Gaps = 13/363 (3%)

Query: 34  FDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQ 93
           F+ + LS  +L G+ A GFE+PS +Q +AI     G D+I QA+SGTGKT  F+   L  
Sbjct: 64  FESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLIVQAKSGTGKTCVFSTIALDS 123

Query: 94  IELDLKATQALVLAPTRELAQQIQKVVMALGDYM-GASCHACIGGTNVRAEVQKLQMEAP 152
           + L+  +TQ L+LAPTRE+A QI  V+ A+G  M G  CH  IGGT +  +  K +++  
Sbjct: 124 LVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECHVFIGGTPLSQD--KTRLKKC 181

Query: 153 HIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRG-FKDQIYDIFQKLNSNTQVVL 211
           HI VG+PGR+  ++   YL+P  I++F+LDEAD++L  G F++QI  I+  L ++ Q++ 
Sbjct: 182 HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSFQEQINWIYSSLPASKQMLA 241

Query: 212 LSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVERE-------EWKLDTLC 264
           +SAT P  +     K+MRDP  + +   + +L G++Q+Y  V          E K   L 
Sbjct: 242 VSATYPEFLANALTKYMRDPTFVRLNSSDPSLIGLKQYYKVVNSYPLAHKVFEEKTQHLQ 301

Query: 265 DLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324
           +L+  +   QA++F N   +   L + + ++ F    + G+M+Q +R   M + +    R
Sbjct: 302 ELFSRIPFNQALVFSNLHSRAQHLADILSSKGFPAECISGNMNQNQRLDAMAKLKHFHCR 361

Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVT--EEDKR 382
           VLI+TDL +RGID ++V+LV+N D+P + E Y+HRIGR GRFG  G+ +      EE+  
Sbjct: 362 VLISTDLTSRGIDAEKVNLVVNLDVPLDWETYMHRIGRAGRFGTLGLTVTYCCRGEEENM 421

Query: 383 TLR 385
            +R
Sbjct: 422 MMR 424


>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
           sapiens]
          Length = 796

 Score =  210 bits (535), Expect = 2e-54
 Identities = 126/383 (32%), Positives = 214/383 (55%), Gaps = 16/383 (4%)

Query: 16  GMEPEGVIE--SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVI 73
           G E  G  E  S ++E + SF DMNLS  LL+ I A GF++P+ IQ+  I   + G D+ 
Sbjct: 201 GQEAGGFFEDASQYDENL-SFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDIC 259

Query: 74  AQAQSGTGKTATFAISILQQI---ELDLKATQALVLAPTRELAQQIQKVVMALGDYMGAS 130
           A A +GTGKTA FA+ +L+++         T+ LVL PTREL  Q+  V   L  +   +
Sbjct: 260 ACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQVHSVTRQLAQFCNIT 319

Query: 131 CHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKY----IKMFVLDEADE 186
               +GG +V+++   L+  AP I++ TPGR+ D L+     P +    I++ +LDEAD 
Sbjct: 320 TCLAVGGLDVKSQEAALRA-APDILIATPGRLIDHLHN---CPSFHLSSIEVLILDEADR 375

Query: 187 MLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGI 246
           ML   F++Q+ +I +  + + Q +L SATM  +V ++    +++P+RI V         +
Sbjct: 376 MLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFL 435

Query: 247 RQFYINVE-REEWKLDTLCDLYETLTITQAV-IFINTRRKVDWLTEKMHARDFTVSAMHG 304
           RQ +I +    E   + +     T T T  V +F  T+++   +   +      V  +HG
Sbjct: 436 RQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLMGLQVGELHG 495

Query: 305 DMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGG 364
           ++ Q +R   +R F+     +L+ TD+ ARG+D++ V  VIN+ +P   ++Y+HR+GR  
Sbjct: 496 NLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTA 555

Query: 365 RFGRKGVAINMVTEEDKRTLRDI 387
           R GR G ++++V E++++ L++I
Sbjct: 556 RAGRAGRSVSLVGEDERKMLKEI 578


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score =  203 bits (517), Expect = 2e-52
 Identities = 118/366 (32%), Positives = 197/366 (53%), Gaps = 11/366 (3%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           + S+    +S  +L  +  +G+EKP+ IQ +AI   + G D+I  A++G+GKT  F + +
Sbjct: 371 IKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPM 430

Query: 91  LQQIELDLKATQ------ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEV 144
            + I +D ++ +      A+++ PTRELA QI K        +G       GGT +  ++
Sbjct: 431 FRHI-MDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQI 489

Query: 145 QKLQMEAPHIIVGTPGRVFDML---NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ 201
            +L+  A  IIV TPGR+ DML   + R  + + +   VLDEAD M   GF+ Q+  I  
Sbjct: 490 AELKRGA-EIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVD 548

Query: 202 KLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLD 261
            +  + Q V+ SAT P  +  + ++ +  PI + V    +    + Q  I +E E+  L 
Sbjct: 549 NVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVIEEEKKFLK 608

Query: 262 TLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSG 321
            L  L         +IF++ +   D L + +    +   ++HG +DQ +RD I+ +F++G
Sbjct: 609 LLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDSIINDFKNG 668

Query: 322 SSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDK 381
           + ++L+ T + ARG+DV+ + LV+NY  P + E+Y+HR GR GR G KG A   +TE+  
Sbjct: 669 TCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAYTFITEDQA 728

Query: 382 RTLRDI 387
           R   DI
Sbjct: 729 RYAGDI 734


>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
           [Homo sapiens]
          Length = 455

 Score =  203 bits (516), Expect = 3e-52
 Identities = 119/372 (31%), Positives = 202/372 (54%), Gaps = 3/372 (0%)

Query: 29  EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 88
           E   +F D+ +++ L       G+ KP+ IQ  AI   ++G D+I  A++G+GKT  FA+
Sbjct: 21  EETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAFAL 80

Query: 89  SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 148
            IL  +    +   ALVL PTRELA QI +   ALG  +G      +GG +  ++   L 
Sbjct: 81  PILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLAL- 139

Query: 149 MEAPHIIVGTPGRVFDML-NRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNT 207
            + PHII+ TPGR+ D L N +  + + +K  V+DEAD +L+  F+ ++  I + +  + 
Sbjct: 140 AKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDR 199

Query: 208 QVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLY 267
           +  L SATM   V ++ +  +++P++  V  +  T+E ++Q+YI +   ++K   L  + 
Sbjct: 200 KTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQYYIFIP-SKFKDTYLVYIL 258

Query: 268 ETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLI 327
             L     +IF +T          +    FT   +HG M Q +R   + +F++ +  +L+
Sbjct: 259 NELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILL 318

Query: 328 TTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDI 387
            TD+ +RG+D+  V +V+N+D+PT+ ++YIHR+GR  R GR G AI  VT+ D    + I
Sbjct: 319 ATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRI 378

Query: 388 ETFYNTSIEEMP 399
           E      +   P
Sbjct: 379 EHLIGKKLPGFP 390


>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  202 bits (514), Expect = 4e-52
 Identities = 130/398 (32%), Positives = 216/398 (54%), Gaps = 25/398 (6%)

Query: 25  SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY-DVIAQAQSGTGKT 83
           SN    +++F D+++ E ++  I    + +P+ +Q+ AI P IKG  D++A AQ+G+GKT
Sbjct: 171 SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKT 229

Query: 84  ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125
           A F + IL QI  D     LKA +             +LVLAPTRELA QI +       
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289

Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185
                     GG ++  +++ L+    H++V TPGR+ DM+ R  +   + K  VLDEAD
Sbjct: 290 RSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 348

Query: 186 EMLSRGFKDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241
            ML  GF+ QI  I ++     + V    + SAT P ++  + + F+ + I + V +   
Sbjct: 349 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 408

Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301
           T E I Q  + VE  + +   L  L  T + +  ++F+ T++  D L + ++   +  ++
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468

Query: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361
           +HGD  Q++R+  + +FRSG S +L+ T + ARG+D+  V  VIN+DLP++ E Y+HRIG
Sbjct: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528

Query: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399
           R GR G  G+A +   E++    +D+      + +E+P
Sbjct: 529 RTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566


>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
           [Homo sapiens]
          Length = 660

 Score =  202 bits (514), Expect = 4e-52
 Identities = 130/398 (32%), Positives = 216/398 (54%), Gaps = 25/398 (6%)

Query: 25  SNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGY-DVIAQAQSGTGKT 83
           SN    +++F D+++ E ++  I    + +P+ +Q+ AI P IKG  D++A AQ+G+GKT
Sbjct: 171 SNCPPHIENFSDIDMGEIIMGNIELTRYTRPTPVQKHAI-PIIKGKRDLMACAQTGSGKT 229

Query: 84  ATFAISILQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGD 125
           A F + IL QI  D     LKA +             +LVLAPTRELA QI +       
Sbjct: 230 AAFLLPILSQIYTDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSY 289

Query: 126 YMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEAD 185
                     GG ++  +++ L+    H++V TPGR+ DM+ R  +   + K  VLDEAD
Sbjct: 290 RSRVRPCVVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEAD 348

Query: 186 EMLSRGFKDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEEL 241
            ML  GF+ QI  I ++     + V    + SAT P ++  + + F+ + I + V +   
Sbjct: 349 RMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGS 408

Query: 242 TLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSA 301
           T E I Q  + VE  + +   L  L  T + +  ++F+ T++  D L + ++   +  ++
Sbjct: 409 TSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTS 468

Query: 302 MHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIG 361
           +HGD  Q++R+  + +FRSG S +L+ T + ARG+D+  V  VIN+DLP++ E Y+HRIG
Sbjct: 469 IHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIG 528

Query: 362 RGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399
           R GR G  G+A +   E++    +D+      + +E+P
Sbjct: 529 RTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQEVP 566


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score =  200 bits (508), Expect = 2e-51
 Identities = 122/393 (31%), Positives = 201/393 (51%), Gaps = 37/393 (9%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           + S+ D +L   +L  I   G+++P+ IQ++AI   ++  D+I  A++G+GKTA F I +
Sbjct: 390 IRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPL 449

Query: 91  L---------QQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVR 141
           L          +IE   +   A++LAPTRELAQQI++  +  G  +G    A IGG +  
Sbjct: 450 LVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISRE 509

Query: 142 AEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQ 201
            +  +L+M    I++ TPGR+ D+L  RYL        VLDEAD M+  GF+  +  I +
Sbjct: 510 DQGFRLRMGC-EIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILE 568

Query: 202 KL--------------------------NSNTQVVLLSATMPSDVLEVTKKFMRDPIRIL 235
            +                          +   Q V+ +ATMP  V  + + ++R P  + 
Sbjct: 569 HMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVY 628

Query: 236 VKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHAR 295
           +       E + Q    +   E K   L  + E       +IF+N ++  D L + +   
Sbjct: 629 IGSAGKPHERVEQKVFLMSESE-KRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKM 687

Query: 296 DFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNREN 355
            +    +HG   Q++R+  +   ++G+  +L+ TD+  RGID+Q VS+V+NYD+  N E+
Sbjct: 688 GYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIED 747

Query: 356 YIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIE 388
           YIHRIGR GR G+ GVAI  +T+ED     +++
Sbjct: 748 YIHRIGRTGRAGKSGVAITFLTKEDSAVFYELK 780


>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
           sapiens]
          Length = 648

 Score =  199 bits (507), Expect = 3e-51
 Identities = 125/375 (33%), Positives = 203/375 (54%), Gaps = 10/375 (2%)

Query: 33  SFDD-MNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS-- 89
           +FDD       ++  I   GF+KP+ IQ +A    ++G D+I  AQ+GTGKT  + +   
Sbjct: 242 TFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIVLQGIDLIGVAQTGTGKTLCYLMPGF 301

Query: 90  ILQQIELDLKATQ----ALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ 145
           I   ++  LK  +     LVL PTRELA Q++        Y G       GG N   +++
Sbjct: 302 IHLVLQPSLKGQRNRPGMLVLTPTRELALQVEGECCKYS-YKGLRSVCVYGGGNRDEQIE 360

Query: 146 KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS 205
           +L+ +   II+ TPGR+ D+    +++ K I   VLDEAD+ML  GF+ QI  I   +  
Sbjct: 361 ELK-KGVDIIIATPGRLNDLQMSNFVNLKNITYLVLDEADKMLDMGFEPQIMKILLDVRP 419

Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
           + Q V+ SAT P  V  + + ++++P+ + V   +L      +  I V  EE K   +  
Sbjct: 420 DRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGTLDLVAVSSVKQNIIVTTEEEKWSHMQT 479

Query: 266 LYETLTITQAVI-FINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSR 324
             ++++ T  VI F++ +   D L+  +   + +V ++HGD +Q++R+  +  F++G  R
Sbjct: 480 FLQSMSSTDKVIVFVSRKAVADHLSSDLILGNISVESLHGDREQRDREKALENFKTGKVR 539

Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTL 384
           +LI TDL +RG+DV  V+ V N+D P N E Y+HRIGR GR GR GV+I  +T  D R  
Sbjct: 540 ILIATDLASRGLDVHDVTHVYNFDFPRNIEEYVHRIGRTGRAGRTGVSITTLTRNDWRVA 599

Query: 385 RDIETFYNTSIEEMP 399
            ++      + + +P
Sbjct: 600 SELINILERANQSIP 614


>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
           sapiens]
          Length = 662

 Score =  197 bits (502), Expect = 1e-50
 Identities = 124/391 (31%), Positives = 208/391 (53%), Gaps = 23/391 (5%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           ++SF D+ + E ++  I    + +P+ +Q+ AI    +  D++A AQ+G+GKTA F + I
Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238

Query: 91  LQQIELD-----LKATQ-------------ALVLAPTRELAQQIQKVVMALGDYMGASCH 132
           L QI  D     L+A +             +LVLAPTRELA QI +              
Sbjct: 239 LSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPC 298

Query: 133 ACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGF 192
              GG ++  +++ L+    H++V TPGR+ DM+ R  +   + K  VLDEAD ML  GF
Sbjct: 299 VVYGGADIGQQIRDLERGC-HLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGF 357

Query: 193 KDQIYDIFQKLNSNTQVV----LLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQ 248
           + QI  I ++     + V    + SAT P ++  + + F+ + I + V +   T E I Q
Sbjct: 358 EPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQ 417

Query: 249 FYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQ 308
             + VE  + +   L  L  T   +  ++F+ T++  D L + ++   +  +++HGD  Q
Sbjct: 418 KVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQ 477

Query: 309 KERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGR 368
           ++R+  + +FRSG S +L+ T + ARG+D+  V  VIN+DLP++ E Y+HRIGR GR G 
Sbjct: 478 RDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGN 537

Query: 369 KGVAINMVTEEDKRTLRDIETFYNTSIEEMP 399
            G+A +   E +    +D+      + +E+P
Sbjct: 538 LGLATSFFNERNINITKDLLDLLVEAKQEVP 568


>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
           sapiens]
          Length = 619

 Score =  196 bits (497), Expect = 4e-50
 Identities = 113/363 (31%), Positives = 204/363 (56%), Gaps = 9/363 (2%)

Query: 30  IVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAIS 89
           I+D F+  +L E L   +   G+E P+ IQ + I   + G D++A A +G+GKTA F + 
Sbjct: 202 IID-FEHCSLPEVLNHNLKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTAAFLLP 260

Query: 90  ILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGA-SCHACIGGTNVRAEVQKLQ 148
           ++ +   + K   AL+L PTRELA QI++    L   +        +GG  +  ++ +LQ
Sbjct: 261 VIMRALFESKTPSALILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGLPLPPQLYRLQ 320

Query: 149 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 208
                +I+ TPGR+ D++ +  +    +K+ V+DEAD ML  GF+ Q+ DI + + ++ Q
Sbjct: 321 QHVK-VIIATPGRLLDIIKQSSVELCGVKIVVVDEADTMLKMGFQQQVLDILENIPNDCQ 379

Query: 209 VVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVE---REEWKLDTLCD 265
            +L+SAT+P+ + ++  + + +P+RI+  ++ L    +RQ  + VE   +++   + L D
Sbjct: 380 TILVSATIPTSIEQLASQLLHNPVRIITGEKNLPCANVRQIILWVEDPAKKKKLFEILND 439

Query: 266 LYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS-AMHGDMDQKERDVIMREFRSGSSR 324
             + L     ++F++ +   D L+E +       S ++H +  Q ER  I++    G   
Sbjct: 440 --KKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKNILKGLLEGDYE 497

Query: 325 VLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTL 384
           V+++T +L RG+D+  V LV+N+D+P++ + Y+H+IGR GR G+ G AI  +    KR  
Sbjct: 498 VVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAITFINNNSKRLF 557

Query: 385 RDI 387
            DI
Sbjct: 558 WDI 560


>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
          Length = 731

 Score =  195 bits (496), Expect = 5e-50
 Identities = 121/365 (33%), Positives = 187/365 (51%), Gaps = 9/365 (2%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           V +F   N  + ++  +    F +P+ IQ +     + G D++  AQ+G+GKT  + +  
Sbjct: 170 VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPA 229

Query: 91  LQQIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ 145
           +  I       +      LVLAPTRELAQQ+Q+V    G           GG     +++
Sbjct: 230 IVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289

Query: 146 KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS 205
            L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I  ++  
Sbjct: 290 DLE-RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 348

Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
           + Q ++ SAT P +V ++ + F+RD  +I V   EL+        ++V  E  K   L  
Sbjct: 349 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 408

Query: 266 LYETLTI---TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGS 322
           L E +      + +IF+ T+R+ D LT +M    +    +HGD  Q ERD ++ EFRSG 
Sbjct: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 468

Query: 323 SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382
           + +LI TD+ +RG+DV+ V  VINYD P + E+Y+HRIGR  R   KG A    T  + +
Sbjct: 469 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 528

Query: 383 TLRDI 387
             R++
Sbjct: 529 QAREL 533


>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
          Length = 729

 Score =  195 bits (496), Expect = 5e-50
 Identities = 121/365 (33%), Positives = 187/365 (51%), Gaps = 9/365 (2%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           V +F   N  + ++  +    F +P+ IQ +     + G D++  AQ+G+GKT  + +  
Sbjct: 170 VFAFHHANFPQYVMDVLMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPA 229

Query: 91  LQQIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQ 145
           +  I       +      LVLAPTRELAQQ+Q+V    G           GG     +++
Sbjct: 230 IVHINHQPYLERGDGPICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIR 289

Query: 146 KLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNS 205
            L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I  ++  
Sbjct: 290 DLE-RGVEICIATPGRLIDFLESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRP 348

Query: 206 NTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCD 265
           + Q ++ SAT P +V ++ + F+RD  +I V   EL+        ++V  E  K   L  
Sbjct: 349 DRQTLMWSATWPKEVRQLAEDFLRDYTQINVGNLELSANHNILQIVDVCMESEKDHKLIQ 408

Query: 266 LYETLTI---TQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGS 322
           L E +      + +IF+ T+R+ D LT +M    +    +HGD  Q ERD ++ EFRSG 
Sbjct: 409 LMEEIMAEKENKTIIFVETKRRCDDLTRRMRRDGWPAMCIHGDKSQPERDWVLNEFRSGK 468

Query: 323 SRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKR 382
           + +LI TD+ +RG+DV+ V  VINYD P + E+Y+HRIGR  R   KG A    T  + +
Sbjct: 469 APILIATDVASRGLDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLK 528

Query: 383 TLRDI 387
             R++
Sbjct: 529 QAREL 533


>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
           [Homo sapiens]
          Length = 881

 Score =  195 bits (495), Expect = 7e-50
 Identities = 125/416 (30%), Positives = 210/416 (50%), Gaps = 23/416 (5%)

Query: 1   MSASQDSRSRDNGPDGMEPE-------GVIESNWNEIVDS----------FDDMNLSESL 43
           + A  D+R+R  GP    P          +E +  E+V +          F  M LS  +
Sbjct: 48  IQAEDDARARKLGPGRPLPTFPTSECTSDVEPDTREMVRAQNKKKKKSGGFQSMGLSYPV 107

Query: 44  LRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKAT-- 101
            +GI   G++ P+ IQ++ I   + G DV+A A++G+GKTA F + + ++++     T  
Sbjct: 108 FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGA 167

Query: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161
           +AL+L+PTRELA Q  K    LG + G      +GG  +  +   L  E P II+ TPGR
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALH-ENPDIIIATPGR 226

Query: 162 VFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVL 221
           +  +     L  + ++  V DEAD +   GF +Q+ +I  +L    Q VL SAT+P  ++
Sbjct: 227 LVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLV 286

Query: 222 EVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ--AVIFI 279
           E  +  + +P+ I +  +    E ++  +  V RE+ K   L  L   +   Q   V+F+
Sbjct: 287 EFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVVRPQDQTVVFV 345

Query: 280 NTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQ 339
            T+   ++LTE +  +  + + ++  +D   R + + +F  G    LI TDL ARG+D+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 340 QVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSI 395
            +  VINY  P   + ++HR+GR  R GR G A ++V  ++   L D+  F   S+
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLFLGRSL 461


>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
           [Homo sapiens]
          Length = 882

 Score =  195 bits (495), Expect = 7e-50
 Identities = 125/416 (30%), Positives = 210/416 (50%), Gaps = 23/416 (5%)

Query: 1   MSASQDSRSRDNGPDGMEPE-------GVIESNWNEIVDS----------FDDMNLSESL 43
           + A  D+R+R  GP    P          +E +  E+V +          F  M LS  +
Sbjct: 48  IQAEDDARARKLGPGRPLPTFPTSECTSDVEPDTREMVRAQNKKKKKSGGFQSMGLSYPV 107

Query: 44  LRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKAT-- 101
            +GI   G++ P+ IQ++ I   + G DV+A A++G+GKTA F + + ++++     T  
Sbjct: 108 FKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFERLKTHSAQTGA 167

Query: 102 QALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGR 161
           +AL+L+PTRELA Q  K    LG + G      +GG  +  +   L  E P II+ TPGR
Sbjct: 168 RALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALH-ENPDIIIATPGR 226

Query: 162 VFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVL 221
           +  +     L  + ++  V DEAD +   GF +Q+ +I  +L    Q VL SAT+P  ++
Sbjct: 227 LVHVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQTVLFSATLPKLLV 286

Query: 222 EVTKKFMRDPIRILVKKEELTLEGIRQFYINVEREEWKLDTLCDLYETLTITQ--AVIFI 279
           E  +  + +P+ I +  +    E ++  +  V RE+ K   L  L   +   Q   V+F+
Sbjct: 287 EFARAGLTEPVLIRLDVDTKLNEQLKTSFFLV-REDTKAAVLLHLLHNVVRPQDQTVVFV 345

Query: 280 NTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQ 339
            T+   ++LTE +  +  + + ++  +D   R + + +F  G    LI TDL ARG+D+ 
Sbjct: 346 ATKHHAEYLTELLTTQRVSCAHIYSALDPTARKINLAKFTLGKCSTLIVTDLAARGLDIP 405

Query: 340 QVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSI 395
            +  VINY  P   + ++HR+GR  R GR G A ++V  ++   L D+  F   S+
Sbjct: 406 LLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYLLDLHLFLGRSL 461


>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
          Length = 614

 Score =  193 bits (491), Expect = 2e-49
 Identities = 123/371 (33%), Positives = 196/371 (52%), Gaps = 25/371 (6%)

Query: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
           +F + N   +++  I    F +P+AIQ +     + G D++  AQ+G+GKT ++ +  + 
Sbjct: 95  NFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIV 154

Query: 93  QIELDLKATQA-----LVLAPTRELAQQIQKVVMALGDYMGASCHAC-------IGGTNV 140
            I       +      LVLAPTRELAQQ+Q+V     +Y    C AC        GG   
Sbjct: 155 HINHQPFLERGDGPICLVLAPTRELAQQVQQVA---AEY----CRACRLKSTCIYGGAPK 207

Query: 141 RAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF 200
             +++ L+     I + TPGR+ D L     + +     VLDEAD ML  GF+ QI  I 
Sbjct: 208 GPQIRDLE-RGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIV 266

Query: 201 QKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEELTLEG----IRQFYINVERE 256
            ++  + Q ++ SAT P +V ++ + F++D I I +   EL+       I     +VE++
Sbjct: 267 DQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALELSANHNILQIVDVCHDVEKD 326

Query: 257 EWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316
           E KL  L +   +    + ++F+ T+R+ D LT KM    +    +HGD  Q+ERD ++ 
Sbjct: 327 E-KLIRLMEEIMSEKENKTIVFVETKRRCDELTRKMRRDGWPAMGIHGDKSQQERDWVLN 385

Query: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376
           EF+ G + +LI TD+ +RG+DV+ V  VINYD P + E+YIHRIGR  R  + G A    
Sbjct: 386 EFKHGKAPILIATDVASRGLDVEDVKFVINYDYPNSSEDYIHRIGRTARSTKTGTAYTFF 445

Query: 377 TEEDKRTLRDI 387
           T  + + + D+
Sbjct: 446 TPNNIKQVSDL 456


>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
          Length = 622

 Score =  187 bits (475), Expect = 1e-47
 Identities = 117/385 (30%), Positives = 197/385 (51%), Gaps = 20/385 (5%)

Query: 31  VDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISI 90
           + SF +M    ++LRG+   G   P+ IQ + I   + G D+I  A +G+GKT  F + +
Sbjct: 180 IKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPV 239

Query: 91  L-----QQIELDLKATQA---LVLAPTRELAQQIQKVVMALGDYMGAS------CHACIG 136
           +     Q+  L     +    L++ P+RELA+Q   ++      +         C  CIG
Sbjct: 240 IMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIG 299

Query: 137 GTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQI 196
           G +V+ +++ ++    H++V TPGR+ D+L ++ +S    +   LDEAD M+  GF+  I
Sbjct: 300 GMSVKEQMETIR-HGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDI 358

Query: 197 YDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKE-ELTLEGIRQFYINVER 255
             IF       Q +L SATMP  +    K  +  P+ I V +    +L+ I++  +   +
Sbjct: 359 RTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQE--VEYVK 416

Query: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315
           EE K+  L +  +  T    +IF   +  VD + E +  +     A+HG  DQ+ER   +
Sbjct: 417 EEAKMVYLLECLQK-TPPPVLIFAEKKADVDAIHEYLLLKGVEAVAIHGGKDQEERTKAI 475

Query: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINM 375
             FR G   VL+ TD+ ++G+D   +  VINYD+P   ENY+HRIGR GR G  G+A   
Sbjct: 476 EAFREGKKDVLVATDVASKGLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTF 535

Query: 376 VTEE-DKRTLRDIETFYNTSIEEMP 399
           + +  D+  L D++     + +++P
Sbjct: 536 INKACDESVLMDLKALLLEAKQKVP 560


>gi|13129006 nucleolar protein GU2 [Homo sapiens]
          Length = 737

 Score =  185 bits (470), Expect = 6e-47
 Identities = 119/373 (31%), Positives = 201/373 (53%), Gaps = 23/373 (6%)

Query: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
           +F +  +SE  ++ +   G      IQ +   P  +G D+IAQA++GTGKT +FAI +++
Sbjct: 138 AFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFAIPLIE 197

Query: 93  QIELDL------KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK 146
           +++ +       ++ + LVLAPTRELA Q+ K    +   +  +C    GGT+ ++++  
Sbjct: 198 RLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRKLSVACF--YGGTSYQSQINH 255

Query: 147 LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKL--- 203
           ++     I+VGTPGR+ D L    L    ++  VLDE D+ML  GF +Q+ DI  +    
Sbjct: 256 IR-NGIDILVGTPGRIKDHLQSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIHESYKT 314

Query: 204 --NSNTQVVLLSATMPSDVLEVTKKFMR------DPIRILVKKEELTLEGIRQFYINVER 255
               N Q +L SAT P  V +V KK+M+      D +  + +K   T+E +     +  +
Sbjct: 315 DSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLA-IQCHWSQ 373

Query: 256 EEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIM 315
               +  +  +Y   +  +A+IF  T++ V  +    H +      +HGD+ Q +R++ +
Sbjct: 374 RPAVIGDVLQVYSG-SEGRAIIFCETKKNVTEMAMNPHIKQ-NAQCLHGDIAQSQREITL 431

Query: 316 REFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINM 375
           + FR GS +VL+ T++ ARG+D+ +V LVI    P + E+YIHR GR GR GR G+ I  
Sbjct: 432 KGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGRTGICICF 491

Query: 376 VTEEDKRTLRDIE 388
               ++  LR +E
Sbjct: 492 YQPRERGQLRYVE 504


>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
           sapiens]
          Length = 783

 Score =  184 bits (467), Expect = 1e-46
 Identities = 121/372 (32%), Positives = 198/372 (53%), Gaps = 21/372 (5%)

Query: 33  SFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAISILQ 92
           +F +  +SE  ++ +   G      IQ +       G D+IAQA++GTGKT +FAI +++
Sbjct: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246

Query: 93  QIELDL------KATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQK 146
           ++  +L      +A Q LVLAPTRELA Q+ K    +   +  +C    GGT    + ++
Sbjct: 247 KLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKKLSVACF--YGGTPYGGQFER 304

Query: 147 LQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIF-----Q 201
           ++     I+VGTPGR+ D +    L    +K  VLDE D+ML  GF DQ+ +I      +
Sbjct: 305 MR-NGIDILVGTPGRIKDHIQNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKK 363

Query: 202 KLNSNTQVVLLSATMPSDVLEVTKKFMR---DPIRILVKKEELTLEGIRQFYINVEREEW 258
               N Q +L SAT P  V  V KK+M+   + + ++ KK + T   +    I     + 
Sbjct: 364 DSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQ- 422

Query: 259 KLDTLCDLYETLTITQA--VIFINTRRKVDWLTEKMHARDFTVSAMHGDMDQKERDVIMR 316
           +   + D+    +  Q   +IF  T+++   L++    +     ++HGD+ QK+R++ ++
Sbjct: 423 RAAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQ-DAQSLHGDIPQKQREITLK 481

Query: 317 EFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRIGRGGRFGRKGVAINMV 376
            FR+GS  VL+ T++ ARG+D+ +V LVI    P + E+YIHR GR GR GR GV I   
Sbjct: 482 GFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICFY 541

Query: 377 TEEDKRTLRDIE 388
             +++  L  +E
Sbjct: 542 QHKEEYQLVQVE 553


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.136    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,402,397
Number of Sequences: 37866
Number of extensions: 532722
Number of successful extensions: 1486
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 1242
Number of HSP's gapped (non-prelim): 106
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.