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Search of human proteins with 4503515
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503515 eukaryotic translation initiation factor 3, subunit
3 gamma, 40kDa [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503515 eukaryotic translation initiation factor 3, subunit 3... 702 0.0
gi|5031981 proteasome 26S subunit, non-ATPase 14 [Homo sapiens] 65 9e-11
gi|4503519 eukaryotic translation initiation factor 3, subunit 5... 55 1e-07
gi|25777615 proteasome 26S non-ATPase subunit 7 [Homo sapiens] 44 3e-04
gi|90903231 huntingtin [Homo sapiens] 40 0.002
gi|34147637 COP9 signalosome subunit 6 [Homo sapiens] 38 0.016
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re... 36 0.045
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re... 36 0.045
gi|110347429 mediator complex subunit 12 [Homo sapiens] 36 0.059
gi|24307933 transcription factor EB [Homo sapiens] 36 0.059
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 35 0.077
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 35 0.077
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 35 0.10
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 35 0.10
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 35 0.13
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 35 0.13
gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens] 34 0.17
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s... 34 0.17
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.17
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa... 34 0.17
gi|221139761 zinc finger protein 853 [Homo sapiens] 34 0.23
gi|189491748 ataxin 1 [Homo sapiens] 34 0.23
gi|51479158 ataxin 1 [Homo sapiens] 34 0.23
gi|52485606 formin-like 2 [Homo sapiens] 34 0.23
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 34 0.23
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 33 0.29
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 33 0.29
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 33 0.29
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 33 0.29
gi|50083279 centrosome protein 4 [Homo sapiens] 33 0.29
>gi|4503515 eukaryotic translation initiation factor 3, subunit 3
gamma, 40kDa [Homo sapiens]
Length = 352
Score = 702 bits (1812), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGT 60
MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGT
Sbjct: 1 MASRKEGTGSTATSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGT 60
Query: 61 EVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWY 120
EVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWY
Sbjct: 61 EVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWY 120
Query: 121 QSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEK 180
QSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEK
Sbjct: 121 QSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEK 180
Query: 181 DFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLG 240
DFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLG
Sbjct: 181 DFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLG 240
Query: 241 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEED 300
KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEED
Sbjct: 241 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEED 300
Query: 301 LSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN 352
LSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN
Sbjct: 301 LSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN 352
>gi|5031981 proteasome 26S subunit, non-ATPase 14 [Homo sapiens]
Length = 310
Score = 65.1 bits (157), Expect = 9e-11
Identities = 67/282 (23%), Positives = 127/282 (45%), Gaps = 32/282 (11%)
Query: 20 GAAGKGKGKGGSGDS----AVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVVED- 74
G G G+G D+ +QV I L +LK++KH + G EV+ G++LG V+D
Sbjct: 8 GGGMPGLGQGPPTDAPAVDTAEQVYISSLALLKMLKHGRA-GVPMEVM-GLMLGEFVDDY 65
Query: 75 RLEITNCFPFPQH-TEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQS-TYYGSFVTRA 132
+ + + F PQ T + + +Q +M+ L+ + VGWY S +G +++
Sbjct: 66 TVRVIDVFAMPQSGTGVSVEAVDPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGV 125
Query: 133 LLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVC----KEKDFSPEALK 188
+++Q S++ E +V ++ DPI++ +G + + A+RL M V ++ + L
Sbjct: 126 DINTQQSFEALSERAVAVVVDPIQSVKGKVVIDAFRLINANMMVLGHEPRQTTSNLGHLN 185
Query: 189 KANIT-----FEYMFEEVPIVIKNSHLINVLMWELEKKSAVAD----------KHELLSL 233
K +I + + I + + L ++ L KKS + KH +
Sbjct: 186 KPSIQALIHGLNRHYYSITINYRKNELEQKMLLNLHKKSWMEGLTLQDYSEHCKHNESVV 245
Query: 234 ASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKH 275
L KN ++ D+M+ + ++N KQ ++H
Sbjct: 246 KEMLELAKNYNKAVEEEDKMTPE----QLAIKNVGKQDPKRH 283
>gi|4503519 eukaryotic translation initiation factor 3, subunit 5
epsilon, 47kDa [Homo sapiens]
Length = 357
Score = 54.7 bits (130), Expect = 1e-07
Identities = 39/155 (25%), Positives = 69/155 (44%), Gaps = 10/155 (6%)
Query: 13 TSSSSTAGAAGKGKGKGGSGDSAVKQVQIDGLVVLKIIKHYQEEGQGTEVVQGVLLGLVV 72
T + + G A G GG + V++ +++ I+ Y+ +G V G LLG V
Sbjct: 72 TPAPALPGPALPGPFPGG------RVVRLHPVILASIVDSYERRNEGAARVIGTLLGTVD 125
Query: 73 EDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHLHVGWYQSTYYGSFVTRA 132
+ +E+TNCF P + +D ++++ M + V+ + L +GWY + G +T
Sbjct: 126 KHSVEVTNCFSVPHNESEDEVAVDMEFAKNMYELHKKVSPNELILGWYAT---GHDITEH 182
Query: 133 LLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAY 167
+ Y + L D G +S+KAY
Sbjct: 183 SVLIHEYYSREAPNPIHLTVD-TSLQNGRMSIKAY 216
>gi|25777615 proteasome 26S non-ATPase subunit 7 [Homo sapiens]
Length = 324
Score = 43.5 bits (101), Expect = 3e-04
Identities = 31/94 (32%), Positives = 47/94 (50%), Gaps = 7/94 (7%)
Query: 35 AVKQVQIDGLVVLKIIKHYQEEGQ--GTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDA 92
AV++V + LV+L ++ H+ G+ + V GVLLG + L+++N F P EDD
Sbjct: 5 AVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVP-FDEDDK 63
Query: 93 D----FDEVQYQMEMMRSLRHVNIDHLHVGWYQS 122
D F + Y M + VN VGWY +
Sbjct: 64 DDSVWFLDHDYLENMYGMFKKVNARERIVGWYHT 97
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 40.4 bits (93), Expect = 0.002
Identities = 21/50 (42%), Positives = 30/50 (60%), Gaps = 3/50 (6%)
Query: 269 KQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLL 318
+QQQQ+ Q QQ++QQ+ Q+Q + PP P +L PQPP + LL
Sbjct: 18 QQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQL---PQPPPQAQPLL 64
>gi|34147637 COP9 signalosome subunit 6 [Homo sapiens]
Length = 327
Score = 37.7 bits (86), Expect = 0.016
Identities = 30/125 (24%), Positives = 52/125 (41%), Gaps = 17/125 (13%)
Query: 12 ATSSSSTAGAAGKGKGKGGSGDSAVK------------QVQIDGLVVLKIIKHY----QE 55
A ++++ A G G G D+AV V + LV+L I H+ +
Sbjct: 2 AAAAAAAAATNGTGGSSGMEVDAAVVPSVMACGVTGSVSVALHPLVILNISDHWIRMRSQ 61
Query: 56 EGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRHVNIDHL 115
EG+ +V+ G L+G +E+ N F HT ++ + +Y + V +
Sbjct: 62 EGRPVQVI-GALIGKQEGRNIEVMNSFELLSHTVEEKIIIDKEYYYTKEEQFKQVFKELE 120
Query: 116 HVGWY 120
+GWY
Sbjct: 121 FLGWY 125
>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform a [Homo sapiens]
Length = 1590
Score = 36.2 bits (82), Expect = 0.045
Identities = 14/30 (46%), Positives = 23/30 (76%)
Query: 269 KQQQQKHQYQQRRQQENMQRQSRGEPPLPE 298
+QQQQ+ Q QQ++QQ+ Q+Q + +PP P+
Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQ 247
Score = 28.9 bits (63), Expect = 7.3
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 8/39 (20%)
Query: 272 QQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQP 310
QQ+ Q QQ++QQ+ Q+Q + + P + PPQP
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQ--------PPQP 246
>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin a2 isoform b [Homo sapiens]
Length = 1572
Score = 36.2 bits (82), Expect = 0.045
Identities = 14/30 (46%), Positives = 23/30 (76%)
Query: 269 KQQQQKHQYQQRRQQENMQRQSRGEPPLPE 298
+QQQQ+ Q QQ++QQ+ Q+Q + +PP P+
Sbjct: 218 QQQQQQQQQQQQQQQQQQQQQPQQQPPQPQ 247
Score = 28.9 bits (63), Expect = 7.3
Identities = 14/39 (35%), Positives = 22/39 (56%), Gaps = 8/39 (20%)
Query: 272 QQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQP 310
QQ+ Q QQ++QQ+ Q+Q + + P + PPQP
Sbjct: 216 QQQQQQQQQQQQQQQQQQQQQQQPQQQ--------PPQP 246
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 35.8 bits (81), Expect = 0.059
Identities = 17/57 (29%), Positives = 30/57 (52%), Gaps = 2/57 (3%)
Query: 252 EMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQE--NMQRQSRGEPPLPEEDLSKLFK 306
+ Q I++ + +QQQQ+ Q QQ++QQ+ Q+Q + PP P+ F+
Sbjct: 2082 QQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Score = 33.5 bits (75), Expect = 0.29
Identities = 14/41 (34%), Positives = 25/41 (60%)
Query: 270 QQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQP 310
+QQQ+ Q QQ++QQ+ Q+Q + + ++ + PPQP
Sbjct: 2089 RQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQP 2129
Score = 32.7 bits (73), Expect = 0.50
Identities = 18/74 (24%), Positives = 34/74 (45%)
Query: 244 QLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSK 303
Q ++ + + Q + + +QQQQ+HQ QQ++Q Q Q + +P + L +
Sbjct: 2085 QQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQ 2144
Query: 304 LFKPPQPPARMDSL 317
+ Q A + L
Sbjct: 2145 TQQQQQTAALVRQL 2158
Score = 30.4 bits (67), Expect = 2.5
Identities = 12/41 (29%), Positives = 26/41 (63%)
Query: 269 KQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQ 309
+QQQQ+ Q QQ++QQ+ Q+Q + + + ++ ++ + Q
Sbjct: 2052 QQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQ 2092
Score = 29.3 bits (64), Expect = 5.6
Identities = 12/34 (35%), Positives = 21/34 (61%)
Query: 258 VKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSR 291
V+ + +QQQQ+ Q QQ++QQ+ Q+Q +
Sbjct: 2042 VRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQ 2075
>gi|24307933 transcription factor EB [Homo sapiens]
Length = 476
Score = 35.8 bits (81), Expect = 0.059
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 16/96 (16%)
Query: 264 MRNTSKQQQQKHQYQQR------RQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSL 317
MR ++Q++Q+ + QQ+ +QQ+ Q+Q G PP P + F+ P PP + L
Sbjct: 12 MREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSP-PPVPGEVL 70
Query: 318 LIAGQI---------NTYCQNIKEFTAQNLGKLFMA 344
+ + + Q ++E+ ++ G F A
Sbjct: 71 KVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAA 106
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 35.4 bits (80), Expect = 0.077
Identities = 49/231 (21%), Positives = 95/231 (41%), Gaps = 22/231 (9%)
Query: 131 RALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKA 190
+ L+ ++ +H+ + ++ + + + S A++ P+ E +E LKK
Sbjct: 3575 KELVQTEIQERHSFTKEIIALKNFFQQTTTSFQNMAFQDHPEKSEQFEELQ---SILKKG 3631
Query: 191 NITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRV 250
+TFE + E+ + IK S + ++ E+E + K +L + N L
Sbjct: 3632 KLTFENIMEK--LRIKYSEMYTIVPAEIESQVEECRK----ALEDIDEKISNEVLKSSPS 3685
Query: 251 DEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFK---- 306
M + I + N + N K QQK + ++ Q+ +Q++ E L L++L
Sbjct: 3686 YAMRRKIEEINNGLHNVEKMLQQKSKNIEKAQE--IQKKMWDELDLWHSKLNELDSEVQD 3743
Query: 307 -----PPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN 352
P Q MD+L+I Q E L K + ++EY++
Sbjct: 3744 IVEQDPGQAQEWMDNLMIPFQQYQQVSQRAECRTSQLNKATV--KMEEYSD 3792
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 35.4 bits (80), Expect = 0.077
Identities = 49/231 (21%), Positives = 95/231 (41%), Gaps = 22/231 (9%)
Query: 131 RALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKA 190
+ L+ ++ +H+ + ++ + + + S A++ P+ E +E LKK
Sbjct: 3575 KELVQTEIQERHSFTKEIIALKNFFQQTTTSFQNMAFQDHPEKSEQFEELQ---SILKKG 3631
Query: 191 NITFEYMFEEVPIVIKNSHLINVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRV 250
+TFE + E+ + IK S + ++ E+E + K +L + N L
Sbjct: 3632 KLTFENIMEK--LRIKYSEMYTIVPAEIESQVEECRK----ALEDIDEKISNEVLKSSPS 3685
Query: 251 DEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFK---- 306
M + I + N + N K QQK + ++ Q+ +Q++ E L L++L
Sbjct: 3686 YAMRRKIEEINNGLHNVEKMLQQKSKNIEKAQE--IQKKMWDELDLWHSKLNELDSEVQD 3743
Query: 307 -----PPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQALQEYNN 352
P Q MD+L+I Q E L K + ++EY++
Sbjct: 3744 IVEQDPGQAQEWMDNLMIPFQQYQQVSQRAECRTSQLNKATV--KMEEYSD 3792
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 35.0 bits (79), Expect = 0.10
Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
Query: 255 QDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPP 311
Q I + ++ ++ Q Q+ Q QQ++QQ+ Q+ + +PP+ + + + PQPP
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ----PQPP 281
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 35.0 bits (79), Expect = 0.10
Identities = 16/57 (28%), Positives = 32/57 (56%), Gaps = 4/57 (7%)
Query: 255 QDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPP 311
Q I + ++ ++ Q Q+ Q QQ++QQ+ Q+ + +PP+ + + + PQPP
Sbjct: 229 QQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQ----PQPP 281
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 250 VDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQ 309
V + S++++ ++ + + QQ+ Q QQ++QQ+ Q+Q + + ++ PP
Sbjct: 1226 VAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPN 1285
Query: 310 PPA--RMDSLL 318
A MD LL
Sbjct: 1286 VTASPSMDGLL 1296
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 242 NLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDL 301
N Q++ R E+ + +QQQQ+ Q QQ++QQ+ Q+Q + ++
Sbjct: 1222 NAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQ 1276
Query: 302 SKLFKPPQPPARMDSL--LIAG 321
++ F PP S+ L+AG
Sbjct: 1277 TQAFSPPPNVTASPSMDGLLAG 1298
Score = 30.0 bits (66), Expect = 3.3
Identities = 14/55 (25%), Positives = 27/55 (49%)
Query: 241 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPP 295
++ +LL + ++ + +QQQQ+ Q QQ++QQ+ Q+ PP
Sbjct: 1229 RSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPP 1283
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 34.7 bits (78), Expect = 0.13
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 2/71 (2%)
Query: 250 VDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQ 309
V + S++++ ++ + + QQ+ Q QQ++QQ+ Q+Q + + ++ PP
Sbjct: 1222 VAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPN 1281
Query: 310 PPA--RMDSLL 318
A MD LL
Sbjct: 1282 VTASPSMDGLL 1292
Score = 33.9 bits (76), Expect = 0.23
Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 7/82 (8%)
Query: 242 NLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDL 301
N Q++ R E+ + +QQQQ+ Q QQ++QQ+ Q+Q + ++
Sbjct: 1218 NAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQ 1272
Query: 302 SKLFKPPQPPARMDSL--LIAG 321
++ F PP S+ L+AG
Sbjct: 1273 TQAFSPPPNVTASPSMDGLLAG 1294
Score = 30.0 bits (66), Expect = 3.3
Identities = 14/55 (25%), Positives = 27/55 (49%)
Query: 241 KNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPP 295
++ +LL + ++ + +QQQQ+ Q QQ++QQ+ Q+ PP
Sbjct: 1225 RSRELLSHHFRQQRVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPP 1279
>gi|172072597 retinoblastoma-like 2 (p130) [Homo sapiens]
Length = 1139
Score = 34.3 bits (77), Expect = 0.17
Identities = 39/159 (24%), Positives = 62/159 (38%), Gaps = 10/159 (6%)
Query: 154 PIKTAQGSLSL-KAYRLTP-KLMEVCKEKDFSPEALKKANITFEYMFEEVPIVIKNSHLI 211
P KT+ SL K Y L +L ++C + D S E KK FE+ + P ++ + HL
Sbjct: 830 PRKTSSLSLFFRKVYHLAAVRLRDLCAKLDISDELRKKIWTCFEFSIIQCPELMMDRHLD 889
Query: 212 NVLMWELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQ 271
+LM + + V + + + N + R ++K RN+
Sbjct: 890 QLLMCAIYVMAKVTKEDK----SFQNIMRCYRTQPQARSQVYRSVLIKGKRKRRNSGSSD 945
Query: 272 QQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLFKPPQP 310
+ H Q + N R SR P+ S PQP
Sbjct: 946 SRSH--QNSPTELNKDRTSRDSSPVMRS--SSTLPVPQP 980
>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1662
Score = 34.3 bits (77), Expect = 0.17
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 225 ADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQE 284
A + ELL A + +N L+ +E + RN ++QQQQ+ Q QQ++QQ+
Sbjct: 1569 AQRQELL--AKVEEVVRNYTFLLRAAEESTA---------RNLNQQQQQQQQQQQQQQQQ 1617
Query: 285 NMQRQSRGEPPLPEEDLSKLFKPPQPP 311
Q+Q + + + + PP P
Sbjct: 1618 QQQQQQQQQQQVAAAAGAATEHPPGSP 1644
>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 34.3 bits (77), Expect = 0.17
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 225 ADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQE 284
A + ELL A + +N L+ +E + RN ++QQQQ+ Q QQ++QQ+
Sbjct: 1717 AQRQELL--AKVEEVVRNYTFLLRAAEESTA---------RNLNQQQQQQQQQQQQQQQQ 1765
Query: 285 NMQRQSRGEPPLPEEDLSKLFKPPQPP 311
Q+Q + + + + PP P
Sbjct: 1766 QQQQQQQQQQQVAAAAGAATEHPPGSP 1792
>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
sapiens]
Length = 1810
Score = 34.3 bits (77), Expect = 0.17
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 11/87 (12%)
Query: 225 ADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQE 284
A + ELL A + +N L+ +E + RN ++QQQQ+ Q QQ++QQ+
Sbjct: 1717 AQRQELL--AKVEEVVRNYTFLLRAAEESTA---------RNLNQQQQQQQQQQQQQQQQ 1765
Query: 285 NMQRQSRGEPPLPEEDLSKLFKPPQPP 311
Q+Q + + + + PP P
Sbjct: 1766 QQQQQQQQQQQVAAAAGAATEHPPGSP 1792
>gi|221139761 zinc finger protein 853 [Homo sapiens]
Length = 659
Score = 33.9 bits (76), Expect = 0.23
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 219 EKKSAVADKHELLSLASSNHLGKNL-----QLLMDRVDEMSQDIVKYNTYMRNTSKQQQQ 273
+++ + + +LL L L + L L ++ E Q ++ ++ + QQQ
Sbjct: 230 QQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQ 289
Query: 274 KHQYQQRRQQENMQRQSRGEPPL-PEED 300
+ Q ++QQE +Q+Q PPL PEE+
Sbjct: 290 QQQQLLQQQQEQLQQQQLQPPPLEPEEE 317
Score = 29.3 bits (64), Expect = 5.6
Identities = 20/87 (22%), Positives = 41/87 (47%), Gaps = 2/87 (2%)
Query: 217 ELEKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEM--SQDIVKYNTYMRNTSKQQQQK 274
EL+++ + +L L H + Q L + M Q + + +QQQ++
Sbjct: 117 ELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQ 176
Query: 275 HQYQQRRQQENMQRQSRGEPPLPEEDL 301
Q QQ ++Q+ +Q+Q + + + E+ L
Sbjct: 177 LQTQQAQEQQVLQQQEQLQQQVQEQQL 203
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 33.9 bits (76), Expect = 0.23
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 246 LMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLF 305
L+ + +SQ + +QQQQ+HQ+QQ++QQ+ Q+Q + P L
Sbjct: 180 LLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAP-----GLI 234
Query: 306 KPPQPP 311
P PP
Sbjct: 235 TPGSPP 240
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 33.9 bits (76), Expect = 0.23
Identities = 20/66 (30%), Positives = 32/66 (48%), Gaps = 5/66 (7%)
Query: 246 LMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENMQRQSRGEPPLPEEDLSKLF 305
L+ + +SQ + +QQQQ+HQ+QQ++QQ+ Q+Q + P L
Sbjct: 180 LLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAP-----GLI 234
Query: 306 KPPQPP 311
P PP
Sbjct: 235 TPGSPP 240
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 33.9 bits (76), Expect = 0.23
Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 17/154 (11%)
Query: 87 HTEDDADFD-EVQYQM------EMMRSLRHVNIDHLHVGWYQSTYYGSFVTRALLDSQFS 139
H+ +D +F +QY+ E + L+H D L V Q+ F ALL+ +
Sbjct: 329 HSVEDMNFRVHLQYEFTKLGLDEYLDKLKHTESDKLQVQ-IQAYLDNVFDVGALLEDAET 387
Query: 140 YQHAIE------ESVVLIYDPIKTAQGSLSLKAYRLTPKLMEVCKEKDFSPEALKKANI- 192
A+E E++ + + ++ + K L +LM+ KE D E K AN
Sbjct: 388 KNAALERVEELEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQ 447
Query: 193 --TFEYMFEEVPIVIKNSHLINVLMWELEKKSAV 224
T M +E I+ + + ELEK+ +
Sbjct: 448 VHTLRKMVKEKEEAIQRQSTLEKKIHELEKQGTI 481
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 33.9 bits (76), Expect = 0.23
Identities = 13/32 (40%), Positives = 22/32 (68%)
Query: 264 MRNTSKQQQQKHQYQQRRQQENMQRQSRGEPP 295
++ +QQQQ+ Q QQ++QQ+ Q+Q + PP
Sbjct: 260 LQQQQQQQQQQQQQQQQQQQQQQQQQLQARPP 291
Score = 29.6 bits (65), Expect = 4.3
Identities = 12/31 (38%), Positives = 22/31 (70%)
Query: 269 KQQQQKHQYQQRRQQENMQRQSRGEPPLPEE 299
+QQQQ+ Q QQ++QQ+ Q+Q + + P++
Sbjct: 263 QQQQQQQQQQQQQQQQQQQQQQQLQARPPQQ 293
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 33.5 bits (75), Expect = 0.29
Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 219 EKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQ 278
++++ + + +L +LQLL + + Q +QQQQ+ Q Q
Sbjct: 124 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ-------------QQQQQQQQQQ 170
Query: 279 QRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQI 323
Q++QQ+ Q+Q + + ++ K K Q + L A Q+
Sbjct: 171 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 215
Score = 32.7 bits (73), Expect = 0.50
Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 227 KHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENM 286
+ ++LS L + Q +M + ++ + K + QQQQ+ Q QQ++QQ+
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
Query: 287 QRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQA 346
Q+Q + + ++ + + Q P + A + Q ++ AQ L +F Q
Sbjct: 169 QQQQQQQQQQQQQQQQQQQQQQQHPGKQ-----AKEQQQQQQQQQQLAAQQL--VFQQQL 221
Query: 347 LQ 348
LQ
Sbjct: 222 LQ 223
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 33.5 bits (75), Expect = 0.29
Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 219 EKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQ 278
++++ + + +L +LQLL + + Q +QQQQ+ Q Q
Sbjct: 32 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ-------------QQQQQQQQQQ 78
Query: 279 QRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQI 323
Q++QQ+ Q+Q + + ++ K K Q + L A Q+
Sbjct: 79 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 123
Score = 32.7 bits (73), Expect = 0.50
Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 227 KHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENM 286
+ ++LS L + Q +M + ++ + K + QQQQ+ Q QQ++QQ+
Sbjct: 17 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 76
Query: 287 QRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQA 346
Q+Q + + ++ + + Q P + A + Q ++ AQ L +F Q
Sbjct: 77 QQQQQQQQQQQQQQQQQQQQQQQHPGKQ-----AKEQQQQQQQQQQLAAQQL--VFQQQL 129
Query: 347 LQ 348
LQ
Sbjct: 130 LQ 131
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 33.5 bits (75), Expect = 0.29
Identities = 23/105 (21%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 219 EKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQ 278
++++ + + +L +LQLL + + Q +QQQQ+ Q Q
Sbjct: 149 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ-------------QQQQQQQQQQ 195
Query: 279 QRRQQENMQRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQI 323
Q++QQ+ Q+Q + + ++ K K Q + L A Q+
Sbjct: 196 QQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQL 240
Score = 32.7 bits (73), Expect = 0.50
Identities = 28/122 (22%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 227 KHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQRRQQENM 286
+ ++LS L + Q +M + ++ + K + QQQQ+ Q QQ++QQ+
Sbjct: 134 QQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
Query: 287 QRQSRGEPPLPEEDLSKLFKPPQPPARMDSLLIAGQINTYCQNIKEFTAQNLGKLFMAQA 346
Q+Q + + ++ + + Q P + A + Q ++ AQ L +F Q
Sbjct: 194 QQQQQQQQQQQQQQQQQQQQQQQHPGKQ-----AKEQQQQQQQQQQLAAQQL--VFQQQL 246
Query: 347 LQ 348
LQ
Sbjct: 247 LQ 248
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 33.5 bits (75), Expect = 0.29
Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 18/141 (12%)
Query: 161 SLSLKAYRLTPKLMEVCKEKDFSPEALKKANITFEYMFEEVPIVIKNSHL-INVLMWELE 219
+LSL+ YR T + E LK+ N + + V L + L +LE
Sbjct: 192 ALSLELYRNT-----------ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLE 240
Query: 220 KKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIVKYNTYMRNTSKQQQQKHQYQQ 279
+ + + +L A ++HLGK LQ V Q V+ N ++QQ++K Q+
Sbjct: 241 RAKLLLPQQQLQ--AEADHLGKELQ----SVSAKLQAQVEENELWNRLNQQQEEKMWRQE 294
Query: 280 RRQQENMQRQSRGEPPLPEED 300
+ QE ++ E + E++
Sbjct: 295 EKIQEREEKIQEQEEKIREQE 315
>gi|50083279 centrosome protein 4 [Homo sapiens]
Length = 1140
Score = 33.5 bits (75), Expect = 0.29
Identities = 55/271 (20%), Positives = 99/271 (36%), Gaps = 65/271 (23%)
Query: 50 IKHYQEEGQGTEVVQGVLLGLVVEDRLEITNCFPFPQHTEDDADFDEVQYQMEMMRSLRH 109
+K +Q EG+ + V RLE+ + +H + + E + Q H
Sbjct: 895 VKAHQAEGESSSV------------RLELLSIDTERRHLRERVELLEKEIQ-------EH 935
Query: 110 VNIDHLHVGWYQSTYYGSFVTRALLDSQFSYQHAIEESVVLIYDPIKTAQGSLSLKAYRL 169
+N H Y+S S + +A+ + +H +E ++ D
Sbjct: 936 INAHHA----YESQI--SSMAKAMSRLEEELRHQEDEKATVLND---------------- 973
Query: 170 TPKLMEVCKE----KDFSPEALKKANITFEYMFEEVPIVIKNSHLINVLMWE-------L 218
L E+C + KD + L N+ FE + E+ V S L+ + L
Sbjct: 974 LSSLRELCIKLDSGKDIMTQQLNSKNLEFERVVVELENVKSESDLLKKQLSNERHTVKNL 1033
Query: 219 EKKSAVADKHELLSLASSNHLGKNLQLLMDRVDEMSQDIV---KYNTYMR---------- 265
E A E S +S+ +QLL +++ + + NT +R
Sbjct: 1034 ESLLATNRDKEFHSHLTSHEKDTEIQLLKEKLTLSESKLTSQSRENTMLRAKVAQLQTDY 1093
Query: 266 NTSKQQQQKHQYQQRRQQENMQRQSRGEPPL 296
+ K+Q +Y++ R + M+R PPL
Sbjct: 1094 DALKRQISTERYERERAIQEMRRHGLATPPL 1124
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.367
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,022,448
Number of Sequences: 37866
Number of extensions: 592341
Number of successful extensions: 6672
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 80
Number of HSP's that attempted gapping in prelim test: 4749
Number of HSP's gapped (non-prelim): 990
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.