Guide to the Human Genome
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Search of human proteins with 4503381

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503381 down-regulator of transcription 1 [Homo sapiens]
         (176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503381 down-regulator of transcription 1 [Homo sapiens]           339   6e-94
gi|5453780 nuclear transcription factor Y, beta [Homo sapiens]         73   1e-13
gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens]      60   1e-09
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    39   0.002
gi|197333737 guanylate-binding protein 5 [Homo sapiens]                39   0.002
gi|16418425 guanylate-binding protein 5 [Homo sapiens]                 39   0.002
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]                39   0.002
gi|116875842 tRNA-intron endonuclease 34 [Homo sapiens]                38   0.005
gi|116875840 tRNA-intron endonuclease 34 [Homo sapiens]                38   0.005
gi|206725450 TAF12 RNA polymerase II, TATA box binding protein (...    37   0.009
gi|5032153 TAF12 RNA polymerase II, TATA box binding protein (TB...    37   0.009
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    37   0.009
gi|4507379 TATA box binding protein [Homo sapiens]                     37   0.012
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   36   0.015
gi|22538413 forkhead box P2 isoform III [Homo sapiens]                 36   0.015
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 36   0.015
gi|110347429 mediator complex subunit 12 [Homo sapiens]                36   0.015
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      36   0.020
gi|41281453 serine/threonine kinase 2 [Homo sapiens]                   36   0.020
gi|55956910 meningioma  1 [Homo sapiens]                               35   0.026
gi|221139761 zinc finger protein 853 [Homo sapiens]                    35   0.034
gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo s...    35   0.034
gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...    35   0.034
gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo sa...    35   0.034
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    35   0.034
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...    35   0.044
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ...    35   0.044
gi|194272186 enhancer of polycomb homolog 2 [Homo sapiens]             35   0.044
gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]     34   0.057
gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]    34   0.057

>gi|4503381 down-regulator of transcription 1 [Homo sapiens]
          Length = 176

 Score =  339 bits (870), Expect = 6e-94
 Identities = 176/176 (100%), Positives = 176/176 (100%)

Query: 1   MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK 60
           MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK
Sbjct: 1   MASSSGNDDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNK 60

Query: 61  SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR 120
           SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR
Sbjct: 61  SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELLR 120

Query: 121 QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI 176
           QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI
Sbjct: 121 QQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI 176


>gi|5453780 nuclear transcription factor Y, beta [Homo sapiens]
          Length = 207

 Score = 72.8 bits (177), Expect = 1e-13
 Identities = 37/103 (35%), Positives = 66/103 (64%), Gaps = 2/103 (1%)

Query: 2   ASSSGNDDDLTIPRAAINKMIKETLPNV-RVANDARELVVNCCTEFIHLISSEANEICNK 60
           +  S  + D+ +P A + +++K  +P   ++A DA+E V  C +EFI  I+SEA+E C++
Sbjct: 48  SKESFREQDIYLPIANVARIMKNAIPQTGKIAKDAKECVQECVSEFISFITSEASERCHQ 107

Query: 61  SEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRK 103
            ++KTI+ E ++ A+ +LGF SY+  +K  LQ+ +  A+K  K
Sbjct: 108 EKRKTINGEDILFAMSTLGFDSYVEPLKLYLQKFRE-AMKGEK 149


>gi|224586804 DNA-directed DNA polymerase epsilon 3 [Homo sapiens]
          Length = 147

 Score = 60.1 bits (144), Expect = 1e-09
 Identities = 29/100 (29%), Positives = 58/100 (58%), Gaps = 1/100 (1%)

Query: 9   DDLTIPRAAINKMIKETLPN-VRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
           +DL +P A I ++IKE LP+ V ++ +AR  +    + F+   +S AN    K ++KT++
Sbjct: 6   EDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCANNFAMKGKRKTLN 65

Query: 68  PEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSR 107
              V+ A+E + F  +++ +KE L+  +     +++AS +
Sbjct: 66  ASDVLSAMEEMEFQRFVTPLKEALEAYRREQKGKKEASEQ 105


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 29/86 (33%), Positives = 46/86 (53%), Gaps = 3/86 (3%)

Query: 86   EVKEVLQECKTVALKRRKASSRLENLGIPEEE-LLRQQQELFAKARQQQAELAQQEWLQM 144
            E +E   + +    ++ K   R E +   E+E  L Q +    +AR++Q +  QQ+  Q 
Sbjct: 1235 EEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQARRAHEEARRRQEQ--QQQQRQE 1292

Query: 145  QQAAQQAQLAAASASASNQAGSSQDE 170
            QQ  QQ Q AA +A+A+ QA SSQ +
Sbjct: 1293 QQQQQQQQAAAVAAAATPQAQSSQPQ 1318


>gi|197333737 guanylate-binding protein 5 [Homo sapiens]
          Length = 586

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 6/109 (5%)

Query: 53  EANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLG 112
           +A E+  K  K   S  H I   +       ++E ++  +E +  A   +  + RL  + 
Sbjct: 454 QAEEVLQKYLKSKESVSHAILQTDQA-----LTETEKKKKEAQVKAEAEKAEAQRLAAIQ 508

Query: 113 IPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASAS 161
              E+++++++ L  + + +Q E+A+Q WL  QQ  Q+ Q+   +A  S
Sbjct: 509 RQNEQMMQERERLHQE-QVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLS 556


>gi|16418425 guanylate-binding protein 5 [Homo sapiens]
          Length = 586

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 26/109 (23%), Positives = 53/109 (48%), Gaps = 6/109 (5%)

Query: 53  EANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLG 112
           +A E+  K  K   S  H I   +       ++E ++  +E +  A   +  + RL  + 
Sbjct: 454 QAEEVLQKYLKSKESVSHAILQTDQA-----LTETEKKKKEAQVKAEAEKAEAQRLAAIQ 508

Query: 113 IPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASAS 161
              E+++++++ L  + + +Q E+A+Q WL  QQ  Q+ Q+   +A  S
Sbjct: 509 RQNEQMMQERERLHQE-QVRQMEIAKQNWLAEQQKMQEQQMQEQAAQLS 556


>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
          Length = 2017

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 30/87 (34%), Positives = 44/87 (50%), Gaps = 2/87 (2%)

Query: 88   KEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQ-QEWLQMQQ 146
            KE++ + K V  +R   +S  E     EE+L R Q+E  A  R+ +AE AQ Q  LQ +Q
Sbjct: 966  KELMAQ-KLVQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQ 1024

Query: 147  AAQQAQLAAASASASNQAGSSQDEEDD 173
                A+L A     S +  + Q E D+
Sbjct: 1025 EELLARLEAEKEELSEEIAALQQERDE 1051


>gi|116875842 tRNA-intron endonuclease 34 [Homo sapiens]
          Length = 310

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 23/73 (31%), Positives = 41/73 (56%)

Query: 102 RKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASAS 161
           R  S  L +    +EE  ++Q  L A+AR+ + +   ++  + Q A +Q    A+ AS+S
Sbjct: 77  RHHSLALTSFKRQQEESFQEQSALAAEARETRRQELLEKITEGQAAKKQKLEQASGASSS 136

Query: 162 NQAGSSQDEEDDD 174
            +AGSSQ  ++D+
Sbjct: 137 QEAGSSQAAKEDE 149


>gi|116875840 tRNA-intron endonuclease 34 [Homo sapiens]
          Length = 310

 Score = 37.7 bits (86), Expect = 0.005
 Identities = 23/73 (31%), Positives = 41/73 (56%)

Query: 102 RKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASAS 161
           R  S  L +    +EE  ++Q  L A+AR+ + +   ++  + Q A +Q    A+ AS+S
Sbjct: 77  RHHSLALTSFKRQQEESFQEQSALAAEARETRRQELLEKITEGQAAKKQKLEQASGASSS 136

Query: 162 NQAGSSQDEEDDD 174
            +AGSSQ  ++D+
Sbjct: 137 QEAGSSQAAKEDE 149


>gi|206725450 TAF12 RNA polymerase II, TATA box binding protein
           (TBP)-associated factor, 20 kD [Homo sapiens]
          Length = 161

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 8/106 (7%)

Query: 8   DDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
           +++  + +  +  +++E  PN ++  D  E+++    +FI  + + A ++    +  T+ 
Sbjct: 53  ENNQVLTKKKLQDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLE 112

Query: 68  PEHVIQALESL------GFGSYISEVKEVLQECKTVALKRRKASSR 107
            + V   LE        GFGS   E++   + C T A K+R A  R
Sbjct: 113 VKDVQLHLERQWNMWIPGFGS--EEIRPYKKACTTEAHKQRMALIR 156


>gi|5032153 TAF12 RNA polymerase II, TATA box binding protein
           (TBP)-associated factor, 20 kD [Homo sapiens]
          Length = 161

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 8/106 (7%)

Query: 8   DDDLTIPRAAINKMIKETLPNVRVANDARELVVNCCTEFIHLISSEANEICNKSEKKTIS 67
           +++  + +  +  +++E  PN ++  D  E+++    +FI  + + A ++    +  T+ 
Sbjct: 53  ENNQVLTKKKLQDLVREVDPNEQLDEDVEEMLLQIADDFIESVVTAACQLARHRKSSTLE 112

Query: 68  PEHVIQALESL------GFGSYISEVKEVLQECKTVALKRRKASSR 107
            + V   LE        GFGS   E++   + C T A K+R A  R
Sbjct: 113 VKDVQLHLERQWNMWIPGFGS--EEIRPYKKACTTEAHKQRMALIR 156


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 37.0 bits (84), Expect = 0.009
 Identities = 25/79 (31%), Positives = 42/79 (53%), Gaps = 10/79 (12%)

Query: 84  ISEVKEVLQECKTVALKRRK--ASSRLENLGIPEEE--------LLRQQQELFAKARQQQ 133
           + E+++ LQE   + +K R+   S R+    + EEE         L+++QE + +  QQ+
Sbjct: 431 LEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQE 490

Query: 134 AELAQQEWLQMQQAAQQAQ 152
            E  QQE  Q  ++ QQAQ
Sbjct: 491 KEELQQEMAQQSRSLQQAQ 509



 Score = 31.2 bits (69), Expect = 0.49
 Identities = 29/108 (26%), Positives = 50/108 (46%), Gaps = 10/108 (9%)

Query: 75  LESLGFGSYISEVKEVLQECKTVALKRRKASS----RLENLG------IPEEELLRQQQE 124
           L++ G  S   ++K+  +E +    +RR A      RL+ L       + E ELL++ Q 
Sbjct: 313 LQAEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQR 372

Query: 125 LFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEED 172
              +  Q++ E  + +  ++QQA +     A  A AS QA     EE+
Sbjct: 373 QAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEE 420


>gi|4507379 TATA box binding protein [Homo sapiens]
          Length = 339

 Score = 36.6 bits (83), Expect = 0.012
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 3/62 (4%)

Query: 110 NLGIPEEELLRQQQELFAKARQQQAE---LAQQEWLQMQQAAQQAQLAAASASASNQAGS 166
           +L I EE+  +QQQ+   + +QQQ +     QQ+  Q QQ  QQ Q  A +A+A  Q+ S
Sbjct: 48  SLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTS 107

Query: 167 SQ 168
            Q
Sbjct: 108 QQ 109



 Score = 35.8 bits (81), Expect = 0.020
 Identities = 21/70 (30%), Positives = 37/70 (52%)

Query: 99  LKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASA 158
           ++   + S LE     +++  +QQQ+   + +QQQ +  QQ+  Q QQ  QQ  +AAA+ 
Sbjct: 43  IQNTNSLSILEEQQRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAV 102

Query: 159 SASNQAGSSQ 168
             S    ++Q
Sbjct: 103 QQSTSQQATQ 112



 Score = 31.6 bits (70), Expect = 0.37
 Identities = 16/54 (29%), Positives = 30/54 (55%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQ 168
           +++  +QQQ+   + +QQQ +  QQ+  Q QQA   A +  +++  + Q  S Q
Sbjct: 64  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQ 117



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 15/50 (30%), Positives = 26/50 (52%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQA 164
           +++  +QQQ+   + +QQQ +  QQ+      A QQ+    A+   S QA
Sbjct: 69  QQQQQQQQQQQQQQQQQQQQQQQQQQQAVAAAAVQQSTSQQATQGTSGQA 118


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 36.2 bits (82), Expect = 0.015
 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 8/114 (7%)

Query: 64  KTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRR------KASSRLENLGIPEEE 117
           + I+P+ + Q L+         +++ +LQ+ + V L+++      K      +L + +++
Sbjct: 97  QVITPQQMQQILQQQVLSP--QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 154

Query: 118 LLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
             +QQQ+   + +QQQ +  QQ+  Q QQ  QQ Q       A  Q    Q ++
Sbjct: 155 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 208



 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAA 155
           +++  +QQQ+   + +QQQ    +Q   Q QQ  QQ QLAA
Sbjct: 172 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQL 153
           +++  +QQQ    +A++QQ +  QQ+ L  QQ   Q QL
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 221



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 11/46 (23%)

Query: 114 PEEELLRQQQELFAKARQQQAELA------QQEWLQMQQAAQQAQL 153
           P ++   QQQ+     +QQQ +LA      QQ+ LQMQQ  QQ  L
Sbjct: 193 PGKQAKEQQQQ-----QQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 233



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 14/54 (25%), Positives = 26/54 (48%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQ 168
           +++  +QQQ+   + +QQQ +  QQ+  Q Q   +QA+          Q  + Q
Sbjct: 161 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 214


>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
          Length = 623

 Score = 36.2 bits (82), Expect = 0.015
 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 8/114 (7%)

Query: 64  KTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRR------KASSRLENLGIPEEE 117
           + I+P+ + Q L+         +++ +LQ+ + V L+++      K      +L + +++
Sbjct: 5   QVITPQQMQQILQQQVLSP--QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 62

Query: 118 LLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
             +QQQ+   + +QQQ +  QQ+  Q QQ  QQ Q       A  Q    Q ++
Sbjct: 63  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 116



 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAA 155
           +++  +QQQ+   + +QQQ    +Q   Q QQ  QQ QLAA
Sbjct: 80  QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQL 153
           +++  +QQQ    +A++QQ +  QQ+ L  QQ   Q QL
Sbjct: 91  QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 129



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 11/46 (23%)

Query: 114 PEEELLRQQQELFAKARQQQAELA------QQEWLQMQQAAQQAQL 153
           P ++   QQQ+     +QQQ +LA      QQ+ LQMQQ  QQ  L
Sbjct: 101 PGKQAKEQQQQ-----QQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 141



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 14/54 (25%), Positives = 26/54 (48%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQ 168
           +++  +QQQ+   + +QQQ +  QQ+  Q Q   +QA+          Q  + Q
Sbjct: 69  QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 122


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 36.2 bits (82), Expect = 0.015
 Identities = 27/114 (23%), Positives = 54/114 (47%), Gaps = 8/114 (7%)

Query: 64  KTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRR------KASSRLENLGIPEEE 117
           + I+P+ + Q L+         +++ +LQ+ + V L+++      K      +L + +++
Sbjct: 122 QVITPQQMQQILQQQVLSP--QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQ 179

Query: 118 LLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
             +QQQ+   + +QQQ +  QQ+  Q QQ  QQ Q       A  Q    Q ++
Sbjct: 180 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQ 233



 Score = 29.3 bits (64), Expect = 1.8
 Identities = 16/41 (39%), Positives = 24/41 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAA 155
           +++  +QQQ+   + +QQQ    +Q   Q QQ  QQ QLAA
Sbjct: 197 QQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 14/39 (35%), Positives = 23/39 (58%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQL 153
           +++  +QQQ    +A++QQ +  QQ+ L  QQ   Q QL
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL 246



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 11/46 (23%)

Query: 114 PEEELLRQQQELFAKARQQQAELA------QQEWLQMQQAAQQAQL 153
           P ++   QQQ+     +QQQ +LA      QQ+ LQMQQ  QQ  L
Sbjct: 218 PGKQAKEQQQQ-----QQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 258



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 14/54 (25%), Positives = 26/54 (48%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQ 168
           +++  +QQQ+   + +QQQ +  QQ+  Q Q   +QA+          Q  + Q
Sbjct: 186 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQ 239


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 36.2 bits (82), Expect = 0.015
 Identities = 19/50 (38%), Positives = 29/50 (58%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQA 164
            ++++LRQQQ+   + +QQQ +  QQ+  Q QQ  QQ Q  AA      Q+
Sbjct: 2084 QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQS 2133



 Score = 32.0 bits (71), Expect = 0.28
 Identities = 17/57 (29%), Positives = 27/57 (47%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +++  +QQQ+   + +QQQ  L QQ+  Q QQ  QQ Q          Q    Q ++
Sbjct: 2067 QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQ 2123



 Score = 31.6 bits (70), Expect = 0.37
 Identities = 16/59 (27%), Positives = 29/59 (49%)

Query: 113  IPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +PE++  +QQQ+   + +QQQ +  QQ+   ++Q  QQ  L         Q    Q ++
Sbjct: 2048 LPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQ 2106



 Score = 31.2 bits (69), Expect = 0.49
 Identities = 18/52 (34%), Positives = 24/52 (46%)

Query: 119  LRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDE 170
            +RQQQ+     +QQQ +  QQ+  Q QQ  QQ Q          QA   Q +
Sbjct: 2079 IRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQ 2130



 Score = 30.8 bits (68), Expect = 0.63
 Identities = 15/57 (26%), Positives = 28/57 (49%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +++  +QQQ+ +   +QQQ ++ +Q+  Q QQ  QQ Q          Q    Q ++
Sbjct: 2066 QQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQ 2122



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 16/57 (28%), Positives = 27/57 (47%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +++  +QQQ+   + +QQQ +  QQ   Q QQ A   Q    S     + G  Q ++
Sbjct: 2091 QQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ 2147



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 112  GIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQ-----AAQQAQLAAASASASNQAGS 166
            G+    +L +QQ+   + +QQQ +  QQ+  Q QQ       QQ Q+         Q   
Sbjct: 2041 GVRSTAILPEQQQQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100

Query: 167  SQDEE 171
             Q ++
Sbjct: 2101 QQQQQ 2105



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 14/57 (24%), Positives = 27/57 (47%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +++  +QQQ+   + +QQQ  + QQ+  Q+ +  QQ Q          Q    Q ++
Sbjct: 2058 QQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQQQQQQQQQQQQQ 2114


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 35.8 bits (81), Expect = 0.020
 Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 2/101 (1%)

Query: 76  ESLGFGSYISEVKE-VLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQA 134
           +S+ F   I+   E VLQ+   +   RR+    LE+LG+   E       ++ + +Q+  
Sbjct: 169 QSMLFDKLITNTAEAVLQKMDDMKKMRRQRMRELEDLGV-FNETEESNLNMYTRGKQKDI 227

Query: 135 ELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDD 175
           +   +E    Q+ + ++          +      DE+DDDD
Sbjct: 228 QRTDEETTDNQEGSVESSEEGEDQEHEDDGEDEDDEDDDDD 268


>gi|41281453 serine/threonine kinase 2 [Homo sapiens]
          Length = 1235

 Score = 35.8 bits (81), Expect = 0.020
 Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 10/117 (8%)

Query: 45   EFIHLISSEANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKA 104
            E  + +  EA  I  + EK+    +++++  +       I+EV++  +E +   +KRRK 
Sbjct: 895  EHTNRLRDEAKRIKGEQEKELSKFQNMLKNRKK----EVINEVEKAPKELRKELMKRRKE 950

Query: 105  SSRLENLGIPEEELLRQQQELFAKAR----QQQAELA--QQEWLQMQQAAQQAQLAA 155
                      +E + +QQQEL    +    QQ+AELA  ++E L  +Q   +A+ AA
Sbjct: 951  ELAQSQHAQEQEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAA 1007


>gi|55956910 meningioma  1 [Homo sapiens]
          Length = 1320

 Score = 35.4 bits (80), Expect = 0.026
 Identities = 18/50 (36%), Positives = 28/50 (56%)

Query: 114 PEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQ 163
           P+ + L+QQQ+   + +QQQ +  QQ+  Q QQ  Q A L     ++ NQ
Sbjct: 517 PDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ 566



 Score = 28.9 bits (63), Expect = 2.4
 Identities = 16/48 (33%), Positives = 25/48 (52%)

Query: 116 EELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQ 163
           + L +QQQ+   + +QQQ +  QQ+  Q QQ    A +    AS + Q
Sbjct: 520 QSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQ 567


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 35.0 bits (79), Expect = 0.034
 Identities = 17/51 (33%), Positives = 31/51 (60%)

Query: 102 RKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQ 152
           ++   +L+     E+++L+QQ++L  + ++QQ    QQE LQ QQ  QQ +
Sbjct: 171 QQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE 221



 Score = 33.5 bits (75), Expect = 0.098
 Identities = 20/41 (48%), Positives = 26/41 (63%), Gaps = 1/41 (2%)

Query: 114 PEEELLRQQQELFAKARQQQAEL-AQQEWLQMQQAAQQAQL 153
           PE +L+ QQQ+L  +  Q+Q  L  QQE LQ QQA +Q  L
Sbjct: 148 PELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVL 188



 Score = 32.0 bits (71), Expect = 0.28
 Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 3/66 (4%)

Query: 107 RLENLGIPEEELLRQQQE-LFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAG 165
           +L+   + E++ L+QQQE L  +  Q+Q  L QQE  Q+QQ  Q+ QL         Q  
Sbjct: 158 QLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQE--QLQQQVQEQQLLQQQQEQLQQQQ 215

Query: 166 SSQDEE 171
             Q +E
Sbjct: 216 LLQQQE 221



 Score = 31.6 bits (70), Expect = 0.37
 Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 1/117 (0%)

Query: 60  KSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLGIPEEELL 119
           + +++ +  + ++Q  E L    +  + +E LQ+ + + L +++   + + L   + +L 
Sbjct: 205 QQQQEQLQQQQLLQQQEQLQQQQF-QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQ 263

Query: 120 RQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEEDDDDI 176
           +Q  E      QQQ  L QQE LQ QQ  Q  Q                + E+++++
Sbjct: 264 QQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEV 320



 Score = 29.6 bits (65), Expect = 1.4
 Identities = 17/41 (41%), Positives = 24/41 (58%), Gaps = 1/41 (2%)

Query: 113 IPEEELLRQQQELFAKARQ-QQAELAQQEWLQMQQAAQQAQ 152
           + E++LL+QQQE   + +  QQ E  QQ+  Q QQ   Q Q
Sbjct: 198 VQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQ 238



 Score = 27.3 bits (59), Expect = 7.0
 Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 2/40 (5%)

Query: 115 EEELLRQQQELFAKARQQQAELAQQEWLQM--QQAAQQAQ 152
           + + L +QQEL  +  Q+Q +L  QE LQ   QQ  QQ Q
Sbjct: 338 QRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQ 377


>gi|239757877 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1662

 Score = 35.0 bits (79), Expect = 0.034
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 17/127 (13%)

Query: 53   EANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLG 112
            E    C +      SP H++ A+     GS+   +  +++    +    R  + R E L 
Sbjct: 1522 ELRASCRRVANVDKSPTHMLAAIT----GSF-QVLSSLIETFVRLVFIVRSEAQRQELLA 1576

Query: 113  IPEEE------LLRQQQELFAK------ARQQQAELAQQEWLQMQQAAQQAQLAAASASA 160
              EE       LLR  +E  A+       +QQQ +  QQ+  Q QQ  QQ Q+AAA+ +A
Sbjct: 1577 KVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1636

Query: 161  SNQAGSS 167
            +     S
Sbjct: 1637 TEHPPGS 1643


>gi|89060961 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 35.0 bits (79), Expect = 0.034
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 17/127 (13%)

Query: 53   EANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLG 112
            E    C +      SP H++ A+     GS+   +  +++    +    R  + R E L 
Sbjct: 1670 ELRASCRRVANVDKSPTHMLAAIT----GSF-QVLSSLIETFVRLVFIVRSEAQRQELLA 1724

Query: 113  IPEEE------LLRQQQELFAK------ARQQQAELAQQEWLQMQQAAQQAQLAAASASA 160
              EE       LLR  +E  A+       +QQQ +  QQ+  Q QQ  QQ Q+AAA+ +A
Sbjct: 1725 KVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784

Query: 161  SNQAGSS 167
            +     S
Sbjct: 1785 TEHPPGS 1791


>gi|89059963 PREDICTED: FERM and PDZ domain containing 3 [Homo
            sapiens]
          Length = 1810

 Score = 35.0 bits (79), Expect = 0.034
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 17/127 (13%)

Query: 53   EANEICNKSEKKTISPEHVIQALESLGFGSYISEVKEVLQECKTVALKRRKASSRLENLG 112
            E    C +      SP H++ A+     GS+   +  +++    +    R  + R E L 
Sbjct: 1670 ELRASCRRVANVDKSPTHMLAAIT----GSF-QVLSSLIETFVRLVFIVRSEAQRQELLA 1724

Query: 113  IPEEE------LLRQQQELFAK------ARQQQAELAQQEWLQMQQAAQQAQLAAASASA 160
              EE       LLR  +E  A+       +QQQ +  QQ+  Q QQ  QQ Q+AAA+ +A
Sbjct: 1725 KVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAA 1784

Query: 161  SNQAGSS 167
            +     S
Sbjct: 1785 TEHPPGS 1791


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 35.0 bits (79), Expect = 0.034
 Identities = 20/58 (34%), Positives = 30/58 (51%), Gaps = 3/58 (5%)

Query: 113  IPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDE 170
            + +++ L+QQQ+L    +QQQ +L QQ+ LQ QQ  QQ Q          Q    Q +
Sbjct: 3900 LQQQQQLQQQQQL---QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQ 3954



 Score = 32.7 bits (73), Expect = 0.17
 Identities = 19/57 (33%), Positives = 35/57 (61%), Gaps = 3/57 (5%)

Query: 99   LKRRKASSRLENLGIPEEELLRQQQEL---FAKARQQQAELAQQEWLQMQQAAQQAQ 152
            L++++   + + L   +++ L+QQQ+L     + +QQQ +L QQ+  Q+QQ  QQ Q
Sbjct: 3900 LQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQ 3956



 Score = 32.3 bits (72), Expect = 0.22
 Identities = 17/54 (31%), Positives = 31/54 (57%)

Query: 99   LKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQ 152
            L++++     +   + +++L +QQQ+   + +QQQ    QQ+ LQ QQ  QQ Q
Sbjct: 3912 LQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQ 3965



 Score = 32.3 bits (72), Expect = 0.22
 Identities = 16/57 (28%), Positives = 31/57 (54%)

Query: 115  EEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDEE 171
            +++L +QQQ+   + +QQ  +  QQ+  Q QQ  QQ Q+   + S +  +   Q ++
Sbjct: 3937 QQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQ 3993



 Score = 30.4 bits (67), Expect = 0.83
 Identities = 17/51 (33%), Positives = 24/51 (47%)

Query: 120  RQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQDE 170
            +QQQ+L  + + QQ +L QQ+  Q  Q  QQ QL         Q    Q +
Sbjct: 3915 QQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQ 3965



 Score = 29.3 bits (64), Expect = 1.8
 Identities = 24/71 (33%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 97   VALKRRKASSRLENLGIPEEELLRQQQ--ELFAKARQQQAELAQQEWLQMQQAAQQAQLA 154
            +AL+     SRL    + E +L  QQQ  +L  K +QQQ +  QQ+ L  Q A QQ Q  
Sbjct: 3704 LALRSLGPDSRL----LQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQ 3759

Query: 155  AASASASNQAG 165
                  +   G
Sbjct: 3760 GPGVQTNQALG 3770



 Score = 28.1 bits (61), Expect = 4.1
 Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 6/55 (10%)

Query: 112  GIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGS 166
            G+ + EL +Q+Q      RQ+  EL  ++ +Q     Q+ + AAA+A A    GS
Sbjct: 2671 GLSQTELEKQRQ------RQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGS 2719



 Score = 26.9 bits (58), Expect = 9.2
 Identities = 19/80 (23%), Positives = 39/80 (48%), Gaps = 13/80 (16%)

Query: 88   KEVLQECKTVALKRRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQ-- 145
            ++ LQ+ + +  ++ +   + + L   +++ L+QQQ+   + +QQQ +  QQ+  Q Q  
Sbjct: 3917 QQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976

Query: 146  -----------QAAQQAQLA 154
                       Q  QQ Q+A
Sbjct: 3977 LLNQSRTLLSPQQQQQQQVA 3996


>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
           sapiens]
          Length = 1134

 Score = 34.7 bits (78), Expect = 0.044
 Identities = 18/58 (31%), Positives = 30/58 (51%)

Query: 106 SRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQ 163
           + L+ +   +++ +  QQ+L A   Q+   L QQ+  Q QQ A+Q +L      A NQ
Sbjct: 135 AELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQ 192


>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
           sapiens]
          Length = 1005

 Score = 34.7 bits (78), Expect = 0.044
 Identities = 18/58 (31%), Positives = 30/58 (51%)

Query: 106 SRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQ 163
           + L+ +   +++ +  QQ+L A   Q+   L QQ+  Q QQ A+Q +L      A NQ
Sbjct: 6   AELQEMASRQQQQIEAQQQLLATKEQRLKFLKQQDQRQQQQVAEQEKLKRLKEIAENQ 63


>gi|194272186 enhancer of polycomb homolog 2 [Homo sapiens]
          Length = 807

 Score = 34.7 bits (78), Expect = 0.044
 Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 2/58 (3%)

Query: 112 GIPEEELLRQQQELFAKARQQQAELAQQEWLQMQQAAQQAQLAAASASASNQAGSSQD 169
           GI EE+    QQ+L    RQQ A+L Q++  Q Q ++QQ    A  +S S+    + D
Sbjct: 577 GITEEQFQTHQQQLVQMQRQQLAQLQQKQ--QSQHSSQQTHPKAQGSSTSDCMSKTLD 632


>gi|29789058 WW and C2 domain containing 1 isoform 3 [Homo sapiens]
          Length = 1113

 Score = 34.3 bits (77), Expect = 0.057
 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 6/66 (9%)

Query: 101 RRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQM-----QQAAQQAQLAA 155
           RR+    L++  +  +E L  Q+E++ + +QQ+ ELAQQE+ Q+      +   Q  L +
Sbjct: 89  RREQEHMLKDYLVVAQEALSAQKEIY-QVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVS 147

Query: 156 ASASAS 161
            S+S+S
Sbjct: 148 GSSSSS 153


>gi|242247257 WW and C2 domain containing 1 isoform 2 [Homo sapiens]
          Length = 1118

 Score = 34.3 bits (77), Expect = 0.057
 Identities = 21/66 (31%), Positives = 38/66 (57%), Gaps = 6/66 (9%)

Query: 101 RRKASSRLENLGIPEEELLRQQQELFAKARQQQAELAQQEWLQM-----QQAAQQAQLAA 155
           RR+    L++  +  +E L  Q+E++ + +QQ+ ELAQQE+ Q+      +   Q  L +
Sbjct: 89  RREQEHMLKDYLVVAQEALSAQKEIY-QVKQQRLELAQQEYQQLHAVWEHKLGSQVSLVS 147

Query: 156 ASASAS 161
            S+S+S
Sbjct: 148 GSSSSS 153


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.122    0.323 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,574,011
Number of Sequences: 37866
Number of extensions: 205277
Number of successful extensions: 3540
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 1970
Number of HSP's gapped (non-prelim): 1158
length of query: 176
length of database: 18,247,518
effective HSP length: 95
effective length of query: 81
effective length of database: 14,650,248
effective search space: 1186670088
effective search space used: 1186670088
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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