Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4503357
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503357 docking protein 1 [Homo sapiens]
(481 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503357 docking protein 1 [Homo sapiens] 995 0.0
gi|41406050 docking protein 2 [Homo sapiens] 203 2e-52
gi|221554537 docking protein 3 isoform 1 [Homo sapiens] 183 3e-46
gi|221554539 docking protein 3 isoform 2 [Homo sapiens] 143 3e-34
gi|47575849 docking protein 6 [Homo sapiens] 72 1e-12
gi|29544726 docking protein 5 [Homo sapiens] 72 1e-12
gi|20070302 docking protein 4 [Homo sapiens] 70 4e-12
gi|221554541 docking protein 3 isoform 3 [Homo sapiens] 62 2e-09
gi|5730059 fibroblast growth factor receptor substrate 3 [Homo s... 62 2e-09
gi|110347414 fibroblast growth factor receptor substrate 2 [Homo... 60 6e-09
gi|110347408 fibroblast growth factor receptor substrate 2 [Homo... 60 6e-09
gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens] 42 0.002
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 39 0.014
gi|66529407 tensin [Homo sapiens] 37 0.030
gi|116292174 fidgetin-like 2 [Homo sapiens] 36 0.068
gi|55750053 atrophin-1 [Homo sapiens] 36 0.089
gi|55750041 atrophin-1 [Homo sapiens] 36 0.089
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 35 0.12
gi|77681565 NG5 protein [Homo sapiens] 35 0.12
gi|148727255 microtubule associated serine/threonine kinase fami... 35 0.15
gi|31543148 hypothetical protein LOC79173 [Homo sapiens] 35 0.15
gi|222537752 Src homology 2 domain containing transforming prote... 35 0.20
gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens] 35 0.20
gi|94400925 synaptonemal complex protein 2-like [Homo sapiens] 35 0.20
gi|71274152 hypothetical protein LOC388939 [Homo sapiens] 34 0.26
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 34 0.34
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 34 0.34
gi|54633319 PDZ domain-containing guanine nucleotide exchange fa... 33 0.44
gi|227430410 POU class 5 homeobox 1B [Homo sapiens] 33 0.44
gi|112421108 capicua homolog [Homo sapiens] 33 0.44
>gi|4503357 docking protein 1 [Homo sapiens]
Length = 481
Score = 995 bits (2573), Expect = 0.0
Identities = 481/481 (100%), Positives = 481/481 (100%)
Query: 1 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRL 60
MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRL
Sbjct: 1 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRL 60
Query: 61 DCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCRNAFP 120
DCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCRNAFP
Sbjct: 61 DCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCRNAFP 120
Query: 121 KGSWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEA 180
KGSWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEA
Sbjct: 121 KGSWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEA 180
Query: 181 ERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGND 240
ERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGND
Sbjct: 181 ERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGND 240
Query: 241 IFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLPSPPGPQELLDSPPALYAEPL 300
IFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLPSPPGPQELLDSPPALYAEPL
Sbjct: 241 IFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLPSPPGPQELLDSPPALYAEPL 300
Query: 301 DSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDP 360
DSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDP
Sbjct: 301 DSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDP 360
Query: 361 IYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPL 420
IYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPL
Sbjct: 361 IYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPL 420
Query: 421 LAPKPQGPAFPEPGTATGSGIKSHNSALYSQVQKSGASGSWDCGLSRVGTDKTGVKSEGS 480
LAPKPQGPAFPEPGTATGSGIKSHNSALYSQVQKSGASGSWDCGLSRVGTDKTGVKSEGS
Sbjct: 421 LAPKPQGPAFPEPGTATGSGIKSHNSALYSQVQKSGASGSWDCGLSRVGTDKTGVKSEGS 480
Query: 481 T 481
T
Sbjct: 481 T 481
>gi|41406050 docking protein 2 [Homo sapiens]
Length = 412
Score = 203 bits (517), Expect = 2e-52
Identities = 160/433 (36%), Positives = 209/433 (48%), Gaps = 67/433 (15%)
Query: 2 DGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLD 61
DGAV +G L+LQ Q+ K+WR+ A LY S +ARLE + G RR +
Sbjct: 3 DGAVKQGFLYLQQQQTFGKKWRRFGASLYGGSDCALARLELQE--------GPEKPRRCE 54
Query: 62 C--KVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCRNAF 119
KVIRL++C+ VA E +AF L+T +R +LLAA A WVQ +C AF
Sbjct: 55 AARKVIRLSDCLRVAEAGGEASSPRDTSAFFLETKERLYLLAAPAAERGDWVQAICLLAF 114
Query: 120 PKGSWTLAPTDNPPKLSALEMLENSLYSPT---WEGSQFWVTVQRTEAAERCGLHGSYVL 176
P L+ + +E EN LYS +F VT++ TEA+ERC L GSY L
Sbjct: 115 PGQRKELSGPEGKQSRPCME--ENELYSSAVTVGPHKEFAVTMRPTEASERCHLRGSYTL 172
Query: 177 RVEAERLTLL---TVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTF 233
R L L G Q L WPY LRR+GRDKV FSFEAGRRC SG G F F
Sbjct: 173 RAGESALELWGGPEPGTQ------LYDWPYRFLRRFGRDKVTFSFEAGRRCVSGEGNFEF 226
Query: 234 QTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLPSPPGPQELLDSPP 293
+T QGN+IF A+E AI QK A + LP P P
Sbjct: 227 ETRQGNEIFLALEEAISAQKNAAPA--------TPQPQPATIPASLPRPDSP-------- 270
Query: 294 ALYAEPLDSL----RIAPCPS-----QDSLYSDPLDSTSAQAGE---GVQRKKP--LYWD 339
Y+ P DSL P P+ Q+ Y+ P D+ + G+ G+ P L
Sbjct: 271 --YSRPHDSLPPPSPTTPVPAPRPRGQEGEYAVPFDAVARSLGKNFRGILAVPPQLLADP 328
Query: 340 LYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPK-DAWWCQARVKEEGY 398
LY+ ++ L P+ D IYDEPEG+A + LYD P+EP+ +AW QA +
Sbjct: 329 LYDSIEETL------PPRPDHIYDEPEGVAAL---SLYDSPQEPRGEAWRRQATADRDPA 379
Query: 399 ELPY-NPATDDYA 410
L + PA D++
Sbjct: 380 GLQHVQPAGQDFS 392
>gi|221554537 docking protein 3 isoform 1 [Homo sapiens]
Length = 496
Score = 183 bits (464), Expect = 3e-46
Identities = 137/370 (37%), Positives = 187/370 (50%), Gaps = 18/370 (4%)
Query: 1 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHK----GSSSGGGRGS 56
++ + +G L+ Q +FG K WRK WA+LY P GVARLE ++ + G++ G
Sbjct: 60 LETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGP 119
Query: 57 SRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCR 116
RR + +VIRLA+CVSV P E+ P AF L T +RSHLLAA AW+ +C+
Sbjct: 120 GRRGERRVIRLADCVSVLPADGESCPRDTG-AFLLTTTERSHLLAAQ--HRQAWMGPICQ 176
Query: 117 NAFP-KGSWTLAPTD-NPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSY 174
AFP G + TD PK + M ENS+YS E +F V VQRTEAA RC L G
Sbjct: 177 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 236
Query: 175 VLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQ 234
+L + + + L +++ + L SWPY LR++G DK +FSFEAGRRC SG G F F
Sbjct: 237 LLVLGPDAIQL----REAKGTQALYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFS 292
Query: 235 TAQGNDIFQAVETAIHRQK---AQGKAGQGHDVLRADSHEGEVAEGKL-PSPPGPQELLD 290
T D+ +AV AI RQ+ + Q + RA S G+L PPGP+
Sbjct: 293 TPCAPDLCRAVAGAIARQRERLPELTRPQPCPLPRATSLPSLDTPGELREMPPGPEPPTS 352
Query: 291 SPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLK 350
L SL + P + L S L ++ + G + LY +L L
Sbjct: 353 RKMHLAEPGPQSLPLLLGPEPNDLASG-LYASVCKRASGPPGNEHLYENLCVLEASPTLH 411
Query: 351 AKLTDPKEDP 360
+P E P
Sbjct: 412 GGEPEPHEGP 421
>gi|221554539 docking protein 3 isoform 2 [Homo sapiens]
Length = 330
Score = 143 bits (361), Expect = 3e-34
Identities = 90/221 (40%), Positives = 126/221 (57%), Gaps = 13/221 (5%)
Query: 1 MDGAVMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHK----GSSSGGGRGS 56
++ + +G L+ Q +FG K WRK WA+LY P GVARLE ++ + G++ G
Sbjct: 4 LETPIKDGILYQQHVKFGKKCWRKVWALLYAGGPSGVARLESWEVRDGGLGAAGDRSAGP 63
Query: 57 SRRLDCKVIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAAWVQTLCR 116
RR + +VIRLA+CVSV P E+ P AF L T +RSHLLAA AW+ +C+
Sbjct: 64 GRRGERRVIRLADCVSVLPADGESCPR-DTGAFLLTTTERSHLLAAQ--HRQAWMGPICQ 120
Query: 117 NAFP-KGSWTLAPTD-NPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSY 174
AFP G + TD PK + M ENS+YS E +F V VQRTEAA RC L G
Sbjct: 121 LAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPA 180
Query: 175 VLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVM 215
+L + + + L +++ + L SWPY LR++G DK++
Sbjct: 181 LLVLGPDAIQL----REAKGTQALYSWPYHFLRKFGSDKIL 217
>gi|47575849 docking protein 6 [Homo sapiens]
Length = 331
Score = 71.6 bits (174), Expect = 1e-12
Identities = 67/245 (27%), Positives = 107/245 (43%), Gaps = 28/245 (11%)
Query: 5 VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKV 64
V +G + ++S++ G +R+ W V AS G RLE F + + + R KV
Sbjct: 9 VKQGYVKIRSRKLGI--FRRCWLVFKKASSKGPRRLEKFPDE-------KAAYFRNFHKV 59
Query: 65 IRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAA-WVQTLCRNAFPKGS 123
L ++ + ET A F +T S A ++ A W + LC
Sbjct: 60 TELHNIKNITRLPRETKKHAVAIIFHDET---SKTFACESELEAEEWCKHLCMEC----- 111
Query: 124 WTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERL 183
L N L ++L + + +F V + T + ++G +++ E +
Sbjct: 112 --LGTRLNDISLGEPDLLAAGVQRE--QNERFNVYLMPTPNLD---IYGECTMQITHENI 164
Query: 184 TLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQ 243
L + L+ WP + LRRYGRD F+FE+GR C +G G FTFQT +G I+Q
Sbjct: 165 YLWDI---HNAKVKLVMWPLSSLRRYGRDSTWFTFESGRMCDTGEGLFTFQTREGEMIYQ 221
Query: 244 AVETA 248
V +A
Sbjct: 222 KVHSA 226
>gi|29544726 docking protein 5 [Homo sapiens]
Length = 306
Score = 71.6 bits (174), Expect = 1e-12
Identities = 70/245 (28%), Positives = 105/245 (42%), Gaps = 28/245 (11%)
Query: 5 VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKV 64
V +G + ++S+R G +++ W V AS G RLE F + R + R KV
Sbjct: 9 VKQGYVRIRSRRLGI--YQRCWLVFKKASSKGPKRLEKFSDE-------RAAYFRCYHKV 59
Query: 65 IRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSA-AWVQTLCRNAFPKGS 123
L +VA + T F DT S A ++ A W + L
Sbjct: 60 TELNNVKNVARLPKSTKKHAIGIYFNDDT---SKTFACESDLEADEWCKVLQMEC----- 111
Query: 124 WTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERL 183
+ N L ++L + E ++ + +HG L++ E +
Sbjct: 112 --VGTRINDISLGEPDLLATGVEREQSERFNVYLM-----PSPNLDVHGECALQITYEYI 164
Query: 184 TLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQ 243
L V Q+ ++ L+SWP + LRRYGRD F+FEAGR C +G G F FQT G I+Q
Sbjct: 165 CLWDV--QNPRVK-LISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQ 221
Query: 244 AVETA 248
V +A
Sbjct: 222 KVHSA 226
>gi|20070302 docking protein 4 [Homo sapiens]
Length = 326
Score = 70.1 bits (170), Expect = 4e-12
Identities = 69/246 (28%), Positives = 107/246 (43%), Gaps = 30/246 (12%)
Query: 5 VMEGPLFLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDC-K 63
V +G + ++S++ G +R+ W V +S G RLE + + S G C K
Sbjct: 9 VKQGYVKMKSRKLGI--YRRCWLVFRKSSSKGPQRLEKYPDEKSVCLRG--------CPK 58
Query: 64 VIRLAECVSVAPVTVETPPEPGATAFRLDTAQRSHLLAADAPSSAA-WVQTLCRNAFPKG 122
V ++ V + ET + A F D+A+ D+ A W +TL G
Sbjct: 59 VTEISNVKCVTRLPKETKRQAVAIIFTDDSART---FTCDSELEAEEWYKTLSVECL--G 113
Query: 123 SWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAER 182
S +L+ + + E L +P + Q ++G L++ E
Sbjct: 114 S----------RLNDISLGEPDLLAPGVQCEQTDRFNVFLLPCPNLDVYGECKLQITHEN 163
Query: 183 LTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIF 242
+ L + L+SWP LRRYGRD F+FEAGR C +G G +TFQT +G I+
Sbjct: 164 IYLWDIHNPRV---KLVSWPLCSLRRYGRDATRFTFEAGRMCDAGEGLYTFQTQEGEQIY 220
Query: 243 QAVETA 248
Q V +A
Sbjct: 221 QRVHSA 226
>gi|221554541 docking protein 3 isoform 3 [Homo sapiens]
Length = 228
Score = 61.6 bits (148), Expect = 2e-09
Identities = 34/83 (40%), Positives = 49/83 (59%), Gaps = 4/83 (4%)
Query: 133 PKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGSYVLRVEAERLTLLTVGAQS 192
PK + M ENS+YS E +F V VQRTEAA RC L G +L + + + L ++
Sbjct: 37 PKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQL----REA 92
Query: 193 QILEPLLSWPYTLLRRYGRDKVM 215
+ + L SWPY LR++G DK++
Sbjct: 93 KGTQALYSWPYHFLRKFGSDKIL 115
>gi|5730059 fibroblast growth factor receptor substrate 3 [Homo
sapiens]
Length = 492
Score = 61.6 bits (148), Expect = 2e-09
Identities = 30/83 (36%), Positives = 46/83 (55%), Gaps = 2/83 (2%)
Query: 201 WPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQAVETAIHRQKAQGKAGQ 260
WPY LRRYG D +FSFE+GRRC +G G F F+ ++ +IF ++ + Q +
Sbjct: 57 WPYLCLRRYGYDSNLFSFESGRRCQTGQGIFAFKCSRAEEIFNLLQDLM--QCNSINVME 114
Query: 261 GHDVLRADSHEGEVAEGKLPSPP 283
++ +SH E+ + P PP
Sbjct: 115 EPVIITRNSHPAELDLPRAPQPP 137
>gi|110347414 fibroblast growth factor receptor substrate 2 [Homo
sapiens]
Length = 508
Score = 59.7 bits (143), Expect = 6e-09
Identities = 60/235 (25%), Positives = 95/235 (40%), Gaps = 41/235 (17%)
Query: 172 GSYVLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTF 231
GS ++ + L L T S + W Y LRRYG D +FSFE+GRRC +G G F
Sbjct: 34 GSGIMELTDTELILYTRKRDS------VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIF 87
Query: 232 TFQTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLP-SPPGPQELLD 290
F+ A+ ++F ++ + V+ ++H+ E+ + P +P P
Sbjct: 88 AFKCARAEELFNMLQEIMQNNSINVVE---EPVVERNNHQTELEVPRTPRTPTTPGFAAQ 144
Query: 291 SPPALY-------------AEPLDSLRIAPCPSQDSLYSDPLDSTSAQA-----GEGVQR 332
+ P Y + S+ A PS + PL Q GVQ
Sbjct: 145 NLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQE 204
Query: 333 KKPLYWDLYEHAQQQLLKAKLTDPKEDP---------IYDEPEG----LAPVPPQ 374
++ ++ + ++ A+ + PKE+P I EPEG L P P Q
Sbjct: 205 ERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQ 259
>gi|110347408 fibroblast growth factor receptor substrate 2 [Homo
sapiens]
Length = 508
Score = 59.7 bits (143), Expect = 6e-09
Identities = 60/235 (25%), Positives = 95/235 (40%), Gaps = 41/235 (17%)
Query: 172 GSYVLRVEAERLTLLTVGAQSQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTF 231
GS ++ + L L T S + W Y LRRYG D +FSFE+GRRC +G G F
Sbjct: 34 GSGIMELTDTELILYTRKRDS------VKWHYLCLRRYGYDSNLFSFESGRRCQTGQGIF 87
Query: 232 TFQTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEGEVAEGKLP-SPPGPQELLD 290
F+ A+ ++F ++ + V+ ++H+ E+ + P +P P
Sbjct: 88 AFKCARAEELFNMLQEIMQNNSINVVE---EPVVERNNHQTELEVPRTPRTPTTPGFAAQ 144
Query: 291 SPPALY-------------AEPLDSLRIAPCPSQDSLYSDPLDSTSAQA-----GEGVQR 332
+ P Y + S+ A PS + PL Q GVQ
Sbjct: 145 NLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQE 204
Query: 333 KKPLYWDLYEHAQQQLLKAKLTDPKEDP---------IYDEPEG----LAPVPPQ 374
++ ++ + ++ A+ + PKE+P I EPEG L P P Q
Sbjct: 205 ERKNRTSVHVPLEARVSNAESSTPKEEPSSIEDRDPQILLEPEGVKFVLGPTPVQ 259
>gi|44662836 breast cancer anti-estrogen resistance 1 [Homo sapiens]
Length = 870
Score = 41.6 bits (96), Expect = 0.002
Identities = 59/237 (24%), Positives = 87/237 (36%), Gaps = 48/237 (20%)
Query: 225 PSGPGTFTFQT----AQGNDIFQAVETAIHRQKAQG-----------KAGQGHDVLRADS 269
P GP +Q G+DI+Q V ++ + +G + GQG+ A
Sbjct: 171 PGGPAQDIYQVPPSAGMGHDIYQ-VPPSMDTRSWEGTKPPAKVVVPTRVGQGYVYEAAQP 229
Query: 270 HEGEVAEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEG 329
+ E + PGPQ++ D PP P S Y + T A +G
Sbjct: 230 EQDEYDIPRHLLAPGPQDIYDVPPVRGLLP-------------SQYGQEVYDTPPMAVKG 276
Query: 330 VQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQG------LYDLP--- 380
+ PL ++Y+ ++ L +YD P ++ P G YD+P
Sbjct: 277 PNGRDPLL-EVYDVPPS--VEKGLPPSNHHAVYDVPPSVSKDVPDGPLLREETYDVPPAF 333
Query: 381 --REPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGT 435
+P D + + P PA D Y VPPP P L P G P PGT
Sbjct: 334 AKAKPFDPARTPLVLAAPPPDSP--PAEDVYDVPPP---APDLYDVPPGLRRPGPGT 385
Score = 33.1 bits (74), Expect = 0.57
Identities = 41/140 (29%), Positives = 52/140 (37%), Gaps = 48/140 (34%)
Query: 282 PPGP---QELLDSPPALY-AEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLY 337
P GP +E D PPA A+P D P + L + P DS A+
Sbjct: 317 PDGPLLREETYDVPPAFAKAKPFD-----PARTPLVLAAPPPDSPPAE------------ 359
Query: 338 WDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPRE---PKDAWWCQARVK 394
D+Y+ P +YD P GL P LYD+PRE P + V
Sbjct: 360 -DVYD-----------VPPPAPDLYDVPPGLRRPGPGTLYDVPRERVLPPEV--ADGGVV 405
Query: 395 EEGYELPYNPATDDYAVPPP 414
+ G YAVPPP
Sbjct: 406 DSGV----------YAVPPP 415
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 38.5 bits (88), Expect = 0.014
Identities = 36/154 (23%), Positives = 56/154 (36%), Gaps = 27/154 (17%)
Query: 282 PPGPQELLDSPP--ALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWD 339
PP + L PP + + P ++ R++P P +DS S P + + V R PL
Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSP-PPEDSPMSPPPEESPMSPPPEVSRLSPL--- 656
Query: 340 LYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYE 399
++ P+E P+ PE PP L P+D+
Sbjct: 657 -------PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDS------------- 696
Query: 400 LPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEP 433
P +P +D PP + P + P P P
Sbjct: 697 -PTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Score = 37.7 bits (86), Expect = 0.023
Identities = 40/167 (23%), Positives = 63/167 (37%), Gaps = 18/167 (10%)
Query: 280 PSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYWD 339
P P P+EL SPP ++ R++P P + + P +S + E + P
Sbjct: 553 PLSPPPEELPTSPPP------EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606
Query: 340 -LYEHAQQQLLK-----AKLTDPKED-PIYDEPEGLAPVPPQGLYDLPREPKDAWWCQAR 392
L ++ L ++L+ P ED P+ PE PP + L P +R
Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP-----VVSR 661
Query: 393 VKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGS 439
+ E P +P ++ PP L P P P P + S
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Score = 35.4 bits (80), Expect = 0.12
Identities = 41/164 (25%), Positives = 57/164 (34%), Gaps = 22/164 (13%)
Query: 281 SPPGPQEL-LDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGE-GVQRKKPLYW 338
SPP P + D P ALY + S PL + G+ GVQ + L
Sbjct: 373 SPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEA 432
Query: 339 DLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGY 398
L E L P+E P+ PE PP L P+
Sbjct: 433 PLNEEMPL------LPPPEESPLSPPPEESPTSPPPEASRLSPPPE-------------- 472
Query: 399 ELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGSGIK 442
ELP +P + + P PL P + P P P ++ S ++
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516
Score = 34.7 bits (78), Expect = 0.20
Identities = 37/157 (23%), Positives = 59/157 (37%), Gaps = 13/157 (8%)
Query: 280 PSPPGPQELLDSPP---ALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPL 336
P P P+E SPP + + P + L +P P L S PL+ + + PL
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHL-SRPLEESPLSPPP---EESPL 503
Query: 337 YWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEE 396
L ++ L+ P+E P E PP+ P + ++ +
Sbjct: 504 SPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA------SPLSPPFEESPLSPP 557
Query: 397 GYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEP 433
ELP +P + + PP P+ P + P P P
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Score = 30.0 bits (66), Expect = 4.9
Identities = 35/163 (21%), Positives = 59/163 (36%), Gaps = 19/163 (11%)
Query: 281 SPPGPQELLDSPPALYAEPLDSLRIAPC-PSQDSLYSDPLDSTSAQAGEGVQRKKPLYWD 339
SPP + L PP + P L +P P ++S S L++ + E P
Sbjct: 495 SPPPEESPLSPPPE--SSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEES 552
Query: 340 LYEHAQQQLLKAKLTD-------PKEDPIYDEPEG--LAPVPPQGLYDLPREPKDAWWCQ 390
++L + + P+E P+ PE ++P P P E +
Sbjct: 553 PLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE-------E 605
Query: 391 ARVKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEP 433
+ + E P +P + + PP P+ P + P P P
Sbjct: 606 SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
>gi|66529407 tensin [Homo sapiens]
Length = 1735
Score = 37.4 bits (85), Expect = 0.030
Identities = 50/188 (26%), Positives = 72/188 (38%), Gaps = 30/188 (15%)
Query: 268 DSHEGEVAEGKLP-------SPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDP-- 318
D H A LP SPPGPQ+ S P L A+PL S + A + +P
Sbjct: 808 DFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLN 867
Query: 319 LDSTSAQAGEGVQRKK--------PLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAP 370
L+ A GVQ ++ PL Q + + T P+ + + ++P
Sbjct: 868 LEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSP 927
Query: 371 -------VPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPL--L 421
+ P G P+EP + +A + EG P +P PP + PL L
Sbjct: 928 ELALTIALNPGG---RPKEPHLHSYKEAFEEMEGTS-PSSPPPSGVRSPPGLAKTPLSAL 983
Query: 422 APKPQGPA 429
KP PA
Sbjct: 984 GLKPHNPA 991
Score = 29.3 bits (64), Expect = 8.3
Identities = 44/190 (23%), Positives = 70/190 (36%), Gaps = 25/190 (13%)
Query: 273 EVAEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQR 332
E EG PS P P + SPP L PL +L + P +P D G +R
Sbjct: 954 EEMEGTSPSSPPPSGVR-SPPGLAKTPLSALGLKP--------HNPADILLHPTGVTRRR 1004
Query: 333 KKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQAR 392
+P E + +++ +P+ E +A G EPK +
Sbjct: 1005 IQP------EEDEGKVVVRLSEEPR-----SYVESVARTAVAGPRAQDSEPKS--FSAPA 1051
Query: 393 VKEEGYELPYNPAT--DDYAVPPPRST-KPLLAPKPQGPAFPEPGTATGSGIKSHNSALY 449
+ G+E+P T + P P ST P+L+ G ++ G ++ L
Sbjct: 1052 TQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLL 1111
Query: 450 SQVQKSGASG 459
+SG+ G
Sbjct: 1112 ESGFRSGSLG 1121
>gi|116292174 fidgetin-like 2 [Homo sapiens]
Length = 653
Score = 36.2 bits (82), Expect = 0.068
Identities = 47/182 (25%), Positives = 66/182 (36%), Gaps = 25/182 (13%)
Query: 267 ADSHEGEVAEGKLPSPPGPQELLDSPPALYAEP-LDSLRIAPCPSQDSLYSDPLDSTSAQ 325
A + + G LP PPGP PPA Y P L + P P+ + Y P + A+
Sbjct: 207 AGGYAAQPGYGALPPPPGP------PPAPYLTPGLPAPTPLPAPAPPTAYGFPTAAPGAE 260
Query: 326 AGEGVQRKKPLYW--DLYEHAQQQLLKAKLTDPKEDPIYDEPE----GLAPVPPQGLYDL 379
+G ++RK Y + KA + D P D E G PP
Sbjct: 261 SGLSLKRKAADEGPEGRYRKYAYEPAKAPVADGASYPAADNGECRGNGFRAKPP----GA 316
Query: 380 PREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGS 439
E + +K G + Y P + + P R AP P+G F P T
Sbjct: 317 AEEASGKYGGGVPLKVLGSPV-YGPQLEPFEKFPER------APAPRG-GFAVPSGETPK 368
Query: 440 GI 441
G+
Sbjct: 369 GV 370
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 35.8 bits (81), Expect = 0.089
Identities = 60/267 (22%), Positives = 93/267 (34%), Gaps = 54/267 (20%)
Query: 221 GRRCPSGPGTFTF--------QTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEG 272
GR P G T + QTA+ + +A +++Q G+ ++ ++S E
Sbjct: 31 GRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQ------GRSEEISESESEET 84
Query: 273 EV-----AEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAG 327
E +LP P P +L + LD + D SDP D
Sbjct: 85 NAPKKTKTEQELPRPQSPSDL---------DSLDGRSL-----NDDGSSDPRD-----ID 125
Query: 328 EGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAW 387
+ + P + + L+ P + P L P PQ PR+P+ ++
Sbjct: 126 QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP--LFPPSPQPPDSTPRQPEASF 183
Query: 388 WCQARVKEEGYELPYNPATDDYAVPPPRSTKP-----------LLAPKPQGPAFPEPGTA 436
V GY P P T PP + P +L+ P GP ++
Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASS 243
Query: 437 TG--SGIKSHNSALYS-QVQKSGASGS 460
G +G K H V SGASG+
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGA 270
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 35.8 bits (81), Expect = 0.089
Identities = 60/267 (22%), Positives = 93/267 (34%), Gaps = 54/267 (20%)
Query: 221 GRRCPSGPGTFTF--------QTAQGNDIFQAVETAIHRQKAQGKAGQGHDVLRADSHEG 272
GR P G T + QTA+ + +A +++Q G+ ++ ++S E
Sbjct: 31 GRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQ------GRSEEISESESEET 84
Query: 273 EV-----AEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAG 327
E +LP P P +L + LD + D SDP D
Sbjct: 85 NAPKKTKTEQELPRPQSPSDL---------DSLDGRSL-----NDDGSSDPRD-----ID 125
Query: 328 EGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAW 387
+ + P + + L+ P + P L P PQ PR+P+ ++
Sbjct: 126 QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP--LFPPSPQPPDSTPRQPEASF 183
Query: 388 WCQARVKEEGYELPYNPATDDYAVPPPRSTKP-----------LLAPKPQGPAFPEPGTA 436
V GY P P T PP + P +L+ P GP ++
Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASS 243
Query: 437 TG--SGIKSHNSALYS-QVQKSGASGS 460
G +G K H V SGASG+
Sbjct: 244 VGGPNGGKQHPPPTTPISVSSSGASGA 270
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 35.4 bits (80), Expect = 0.12
Identities = 34/106 (32%), Positives = 42/106 (39%), Gaps = 9/106 (8%)
Query: 341 YEHAQQQLLKAKLTDPKEDPIYDEPEGLAPV---PPQGLYDLPREPKDAWWCQARV--KE 395
Y+ + ++ L +D + PEGL P+ PP G P P V KE
Sbjct: 768 YDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKE 827
Query: 396 EGYELPYNPA-TDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGSG 440
E ELP P PPP P+ P PQ PE GT G G
Sbjct: 828 EPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQ--LVPE-GTPGGGG 870
Score = 32.3 bits (72), Expect = 0.98
Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 5/83 (6%)
Query: 358 EDPIYDEPEGLAP--VPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPR 415
EDPI P G P +PP + R P+ A+ + + E+ +DD V P
Sbjct: 736 EDPIL-APSGTPPPTIPPDETFG-GRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPE 793
Query: 416 STKPLLAPKPQGPAFPEPGTATG 438
PL P P G A P P TG
Sbjct: 794 GLPPLPPPPPSG-ATPPPIAPTG 815
>gi|77681565 NG5 protein [Homo sapiens]
Length = 306
Score = 35.4 bits (80), Expect = 0.12
Identities = 25/74 (33%), Positives = 30/74 (40%), Gaps = 9/74 (12%)
Query: 360 PIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKP 419
P + P A PP G LPR P D + ++E +E P P A PPP P
Sbjct: 85 PHHAPPGPAAGAPPPGCATLPRMPPDPY-----LQETRFEGPLPPPPPAAAAPPP----P 135
Query: 420 LLAPKPQGPAFPEP 433
A Q P F P
Sbjct: 136 APAQTAQAPGFVVP 149
>gi|148727255 microtubule associated serine/threonine kinase family
member 4 isoform a [Homo sapiens]
Length = 2434
Score = 35.0 bits (79), Expect = 0.15
Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 3/109 (2%)
Query: 351 AKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQARVKEEGYELPYNPATDDYA 410
AK + KE P+ P + P PP DL P C + G E P+T + +
Sbjct: 1927 AKEPERKEQPLQRHPSSIPP-PPLTAKDLS-SPAARQHCSSPSHASGREPGAKPSTAEPS 1984
Query: 411 VPPPRSTKPLLAPKPQGPAFPEPGTATGSGIKSH-NSALYSQVQKSGAS 458
P KP+ A P PG G H + +L SQ GA+
Sbjct: 1985 SSPQDPPKPVAAHSESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGAT 2033
>gi|31543148 hypothetical protein LOC79173 [Homo sapiens]
Length = 637
Score = 35.0 bits (79), Expect = 0.15
Identities = 44/196 (22%), Positives = 68/196 (34%), Gaps = 21/196 (10%)
Query: 270 HEGEVAEGKLPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEG 329
H E EGKL P Q+ + P + D +PC +P +Q G
Sbjct: 41 HHPEEPEGKLGPVPSTQQHGEEPGKAVSSSPDEETGSPCRLLRQPEKEPAPLPPSQNSFG 100
Query: 330 VQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWC 389
R P Q K++ T +++ + DE G L + + C
Sbjct: 101 --RFVP-----------QFAKSRKTVTRKEEMKDEDRGSGAF---SLETIAESSAQSPGC 144
Query: 390 QARVKEEGYELPY-----NPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATGSGIKSH 444
Q V+ G L +P D A P S P+ A G + P+ G+G+ +
Sbjct: 145 QLLVETLGVPLQEATELGDPTQADSARPEQSSQSPVQAVPGSGDSQPDDPPDRGTGLSAS 204
Query: 445 NSALYSQVQKSGASGS 460
A + + GA S
Sbjct: 205 QRASQDHLSEQGADDS 220
>gi|222537752 Src homology 2 domain containing transforming protein
D [Homo sapiens]
Length = 340
Score = 34.7 bits (78), Expect = 0.20
Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 18/97 (18%)
Query: 342 EHAQQQLLKAKLTDPKE---------DPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQAR 392
E A KA L P E DP +P P PP Y EP DA W +
Sbjct: 82 EAADMARAKALLGGPGEELEADTEYLDPFDAQPH---PAPPDDGY---MEPYDAQWVMSE 135
Query: 393 VKEEG---YELPYNPATDDYAVPPPRSTKPLLAPKPQ 426
+ G Y+ PY + A PP KP + PQ
Sbjct: 136 LPGRGVQLYDTPYEEQDPETADGPPSGQKPRQSRMPQ 172
Score = 29.3 bits (64), Expect = 8.3
Identities = 44/157 (28%), Positives = 63/157 (40%), Gaps = 19/157 (12%)
Query: 284 GPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDST---SAQAGEGVQRKKPLYWDL 340
GP E L++ Y +P D+ + P P D Y +P D+ S G GVQ LY
Sbjct: 95 GPGEELEADTE-YLDPFDA-QPHPAPPDDG-YMEPYDAQWVMSELPGRGVQ----LYDTP 147
Query: 341 YEHAQQQLLKAKLTD--PKEDPIYDEPEGLAPVPPQGLYDLPREPKDAWWCQA-RVKEEG 397
YE + + P++ + E E P YD P E K +A V+ +
Sbjct: 148 YEEQDPETADGPPSGQKPRQSRMPQEDER-----PADEYDQPWEWKKDHISRAFAVQFDS 202
Query: 398 YELPYNPAT-DDYAVPPPRSTKPLLAPKPQGPAFPEP 433
E P + + PPPRS +P P P +P
Sbjct: 203 PEWERTPGSAKELRRPPPRSPQPAERVDPALPLEKQP 239
>gi|111185957 downstream of tyrosine kinase 7 [Homo sapiens]
Length = 504
Score = 34.7 bits (78), Expect = 0.20
Identities = 28/85 (32%), Positives = 34/85 (40%), Gaps = 12/85 (14%)
Query: 201 WPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFTFQTAQGNDIFQAVETAIHRQKAQGKAGQ 260
W + LRRYG F FE G RC G F +A+G I + I R + K
Sbjct: 152 WKLSDLRRYGAVPSGFIFEGGTRCGYWAGVFFLSSAEGEQI-SFLFDCIVRGISPTKGPF 210
Query: 261 GHDVLRADSHEGEVAEGKLPSPPGP 285
G + D PSPPGP
Sbjct: 211 GLRPVLPD-----------PSPPGP 224
>gi|94400925 synaptonemal complex protein 2-like [Homo sapiens]
Length = 812
Score = 34.7 bits (78), Expect = 0.20
Identities = 17/40 (42%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 348 LLKAKLTDPKEDPIYDEPEG---LAPVPPQGLYDLPREPK 384
L+ L D E P+ EP L PVPP G+ D P++PK
Sbjct: 458 LITLHLNDQSEPPVIGEPASDSHLQPVPPFGVPDFPQQPK 497
>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
Length = 1288
Score = 34.3 bits (77), Expect = 0.26
Identities = 43/184 (23%), Positives = 67/184 (36%), Gaps = 31/184 (16%)
Query: 262 HDVLRADSHEGEVAEGKLPSPPGPQELLDSP-----PALYAEPLDSLRIAPCPSQDSLYS 316
H V +AD + P+ P P + P P + + P R +P P Q L +
Sbjct: 1000 HWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSP-PHQPKLPN 1058
Query: 317 DPLDSTSAQAGEGVQRKKPLYWDLYEHAQQQLLKAKLTDPKEDPIYDEPEGLAPVPPQGL 376
P +S AQ ++ P+ P + P P+ P
Sbjct: 1059 PPPESAPAQC--------------------KVPSPPTQHPEASPPFSIPSPSPPMSPSQE 1098
Query: 377 YDLPREPKDAWWCQARVKEEGYELPYNPATDD-YAVPPPRSTKPLLAPKPQGPAFPEPGT 435
+ R+ +D+ A+V + + + PAT + PP ST L P P P PE G
Sbjct: 1099 HKETRDSEDSQAVIAKVSGNTHSI-FCPATSSLFEAKPPLSTAHPLTP-PSLP--PEAGG 1154
Query: 436 ATGS 439
G+
Sbjct: 1155 PLGN 1158
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 33.9 bits (76), Expect = 0.34
Identities = 53/242 (21%), Positives = 87/242 (35%), Gaps = 33/242 (13%)
Query: 11 FLQSQRFGTKRWRKTWAVLYPASPHGVARLEFFDHKGSSSGGGRGSSRRLDCKVIRLAEC 70
+L+ Q+ G +R+ VL + ARLE++++ R ++ A
Sbjct: 84 YLRKQKHGHRRY----FVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIP 139
Query: 71 VSVAPVTVETPPEPGATAFRLDTAQRSHLLAA------------DAPSSAAWVQTLCRNA 118
+ P V T + + + R D R HL+A + +W L R
Sbjct: 140 PLIPPRRVITLYQCFSVSQRADARYR-HLIALFTQDEYFAMVAENESEQESWYLLLSRLI 198
Query: 119 FPK-----GSWTLAPTDNPPKLSALEMLENSLYSPTWEGSQFWVTVQRTEAAERCGLHGS 173
G+ P P L+A E Y W+ V V+ R L G
Sbjct: 199 LESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQ-----VIVKPRGLGHRKELSGV 253
Query: 174 YVLRVEAERLTLLTVGAQ-SQILEPLLSWPYTLLRRYGRDKVMFSFEAGRRCPSGPGTFT 232
+ L + E + + + + + ++ LLS +RR G + F E GR GPG
Sbjct: 254 FRLCLTDEEVVFVRLNTEVASVVVQLLS-----IRRCGHSEQYFFLEVGRSTVIGPGELW 308
Query: 233 FQ 234
Q
Sbjct: 309 MQ 310
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 33.9 bits (76), Expect = 0.34
Identities = 42/155 (27%), Positives = 52/155 (33%), Gaps = 21/155 (13%)
Query: 279 LPSPPGPQELLDSPPALYAEPLDSLRIAPCPSQDSLYSDPLDSTSAQAGEGVQRKKPLYW 338
LPSPP P A L L+ P P S PL + S QA +
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS-PLATPSPQAPNALA------- 657
Query: 339 DLYEHAQQQLLKAKLTDPKEDPIYD--EPEGLAPVPPQGLYDLPREPKDAWWCQARVKEE 396
LL+A + P P+ P PV P P A A +
Sbjct: 658 -------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA----APPLQV 706
Query: 397 GYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFP 431
P +P A PPP++ PL AP Q P P
Sbjct: 707 PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741
>gi|54633319 PDZ domain-containing guanine nucleotide exchange factor
I [Homo sapiens]
Length = 1601
Score = 33.5 bits (75), Expect = 0.44
Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 6/68 (8%)
Query: 309 PSQDSLYSDPLDSTSAQAGEGVQRKK---PLYWDLYEHAQQQLLKAKLTDPKEDPIYDEP 365
P+ ++ L+ST A++ EG+ K P+Y + ++ L+ +T PK+D Y EP
Sbjct: 1445 PNYGTVKRRVLESTPAESSEGLDPKDATDPVYKTVTSSTEKGLIVYCVTSPKKDDRYREP 1504
Query: 366 EGLAPVPP 373
P PP
Sbjct: 1505 ---PPTPP 1509
>gi|227430410 POU class 5 homeobox 1B [Homo sapiens]
Length = 359
Score = 33.5 bits (75), Expect = 0.44
Identities = 23/74 (31%), Positives = 30/74 (40%), Gaps = 5/74 (6%)
Query: 379 LPREPKDAWWCQARVKEEGYELPYNPATDDYAVPPPRSTKPLLAPKPQGPAFPEPGTATG 438
L ++ W+C R K + Y D A P S P+ P GP F PG +
Sbjct: 268 LEKDVVRVWFCNRRQKGKRSSSDYAQREDFEAAGSPFSGGPVSFPPAPGPHFGTPGYGS- 326
Query: 439 SGIKSHNSALYSQV 452
H +ALYS V
Sbjct: 327 ----PHFTALYSSV 336
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 33.5 bits (75), Expect = 0.44
Identities = 24/64 (37%), Positives = 30/64 (46%), Gaps = 3/64 (4%)
Query: 418 KPLLAPKPQGPAFPEPGTATGSGIKSHNSALYSQVQKSGASGSWDCGLSRVGTDKTGVKS 477
+P L P+P GP P+P A G G S S+ S S AS + L GT K
Sbjct: 507 RPPLDPEPPGP--PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGS-GTFKAQESG 563
Query: 478 EGST 481
+GST
Sbjct: 564 QGST 567
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,058,532
Number of Sequences: 37866
Number of extensions: 1284772
Number of successful extensions: 4570
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 4378
Number of HSP's gapped (non-prelim): 262
length of query: 481
length of database: 18,247,518
effective HSP length: 106
effective length of query: 375
effective length of database: 14,233,722
effective search space: 5337645750
effective search space used: 5337645750
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.