Guide to the Human Genome
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Name: SHD Sequence: fasta or formatted (340aa) NCBI GI: 222537752
Description:

Src homology 2 domain containing transforming protein D

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.9         27           2
 C cysteine            0.6          2           1
 D aspartate           7.9         27           2
 E glutamate           8.8         30           2
 F phenylalanine       2.6          9           1
 G glycine             6.2         21           2
 H histidine           2.4          8           1
 I isoleucine          0.9          3           1
 K lysine              4.1         14           2
 L leucine             9.4         32           2
 M methionine          1.5          5           1
 N asparagine          1.5          5           1
 P proline            13.8         47           3
 Q glutamine           5.6         19           1
 R arginine            7.1         24           2
 S serine              7.1         24           2
 T threonine           2.9         10           1
 V valine              3.8         13           2
 W tryptophan          1.8          6           1
 Y tyrosine            4.1         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Src homology 2 domain containing transforming prote... 
SHB                   0.323   Src homology 2 domain containing adaptor protein B ...
SHF                   0.317   Src homology 2 domain containing F 
SHE                   0.255   Src homology 2 domain containing E 
ABL2                  0.062   arg tyrosine kinase isoform c 
ABL2                  0.062   arg tyrosine kinase isoform b 
ABL2                  0.062   arg tyrosine kinase isoform e 
ABL2                  0.062   arg tyrosine kinase isoform d 
ABL2                  0.062   arg tyrosine kinase isoform a 
ABL1                  0.053   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.053   c-abl oncogene 1, receptor tyrosine kinase isoform b...
SHC1                  0.045   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.045   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.043   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.043   SHC (Src homology 2 domain containing) transforming ...
SH2D2A                0.043   SH2 domain protein 2A isoform 4 
SH2D2A                0.043   SH2 domain protein 2A isoform 3 
SH2D2A                0.043   SH2 domain protein 2A isoform 2 
SH2D2A                0.043   SH2 domain protein 2A isoform 2 
NCK1                  0.040   NCK adaptor protein 1 
SH2B3                 0.039   SH2B adaptor protein 3 
SH2B2                 0.039   SH2B adaptor protein 2 
GRAP2                 0.035   GRB2-related adaptor protein 2 
RASA1                 0.035   RAS p21 protein activator 1 isoform 1 
RASA1                 0.035   RAS p21 protein activator 1 isoform 2 
LOC100291393          0.035   PREDICTED: hypothetical protein XP_002347924 
NCK2                  0.035   NCK adaptor protein 2 isoform A 
NCK2                  0.035   NCK adaptor protein 2 isoform A 
FRK                   0.035   fyn-related kinase 
SHC2                  0.035   SHC (Src homology 2 domain containing) transforming...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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