Search of human proteins with 4502179

Search of human proteins with 4502179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502179 aquaporin 2 [Homo sapiens]
         (271 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502179 aquaporin 2 [Homo sapiens]                                 537   e-153
gi|4502183 aquaporin 5 [Homo sapiens]                                 348   3e-96
gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]       326   1e-89
gi|86792455 aquaporin 6 [Homo sapiens]                                299   2e-81
gi|4755125 aquaporin 4 isoform b [Homo sapiens]                       233   2e-61
gi|4502181 aquaporin 4 isoform a [Homo sapiens]                       233   2e-61
gi|37694062 aquaporin 1 [Homo sapiens]                                230   9e-61
gi|45446752 aquaporin 8 [Homo sapiens]                                119   2e-27
gi|4502187 aquaporin 7 [Homo sapiens]                                  96   3e-20
gi|157266307 aquaporin 9 [Homo sapiens]                                91   1e-18
gi|4826645 aquaporin 3 [Homo sapiens]                                  76   3e-14
gi|22538420 aquaporin 10 [Homo sapiens]                                57   1e-08
gi|40538880 aquaporin 12A [Homo sapiens]                               34   0.12 
gi|156447037 aquaporin 12B [Homo sapiens]                              33   0.26 
gi|83921614 cytochrome b5 outer mitochondrial membrane precursor...    31   1.3  
gi|188528618 solute carrier family 6 (neurotransmitter transport...    30   2.9  
gi|185136021 spinster homolog 2 [Homo sapiens]                         29   3.8  
gi|169168886 PREDICTED: hypothetical protein [Homo sapiens]            29   5.0  
gi|239752881 PREDICTED: hypothetical protein [Homo sapiens]            28   6.5  
gi|239747434 PREDICTED: hypothetical protein [Homo sapiens]            28   6.5  
gi|239741258 PREDICTED: hypothetical protein XP_002342146 [Homo ...    28   6.5  
gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]               28   6.5  
gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]               28   6.5  
gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]                28   6.5  
gi|47933389 solute carrier family 2, member 9 protein isoform 2 ...    28   8.5  
gi|47933387 solute carrier family 2, member 9 protein isoform 1 ...    28   8.5  
gi|24497589 aristaless related homeobox [Homo sapiens]                 28   8.5  

>gi|4502179 aquaporin 2 [Homo sapiens]
          Length = 271

 Score =  537 bits (1383), Expect = e-153
 Identities = 271/271 (100%), Positives = 271/271 (100%)

Query: 1   MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALG 60
           MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALG
Sbjct: 1   MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALG 60

Query: 61  HISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNA 120
           HISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNA
Sbjct: 61  HISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNA 120

Query: 121 LSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTG 180
           LSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTG
Sbjct: 121 LSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTG 180

Query: 181 CSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL 240
           CSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL
Sbjct: 181 CSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL 240

Query: 241 EPDTDWEEREVRRRQSVELHSPQSLPRGTKA 271
           EPDTDWEEREVRRRQSVELHSPQSLPRGTKA
Sbjct: 241 EPDTDWEEREVRRRQSVELHSPQSLPRGTKA 271


>gi|4502183 aquaporin 5 [Homo sapiens]
          Length = 265

 Score =  348 bits (893), Expect = 3e-96
 Identities = 171/259 (66%), Positives = 213/259 (82%), Gaps = 2/259 (0%)

Query: 3   ELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHI 62
           E+ S+AF +AVFAEFLATL+FVFFGLGSAL WP ALP++LQIA+AFGL IGTL QALG +
Sbjct: 4   EVCSVAFLKAVFAEFLATLIFVFFGLGSALKWPSALPTILQIALAFGLAIGTLAQALGPV 63

Query: 63  SGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALS 122
           SG HINPA+T+A LVG  +S+LRA FYVAAQL+GA+AGA +L+ + P + RG+LAVNAL+
Sbjct: 64  SGGHINPAITLALLVGNQISLLRAFFYVAAQLVGAIAGAGILYGVAPLNARGNLAVNALN 123

Query: 123 NSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCS 182
           N+TT GQA+ VEL LT QL LCIFASTD RR    G+PALSIG SV LGHL+GI++TGCS
Sbjct: 124 NNTTQGQAMVVELILTFQLALCIFASTDSRRTSPVGSPALSIGLSVTLGHLVGIYFTGCS 183

Query: 183 MNPARSLAPAVVTGKFDD-HWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKG-L 240
           MNPARS  PAVV  +F   HWVFW+GP+VGA+L ++LY Y+LFP + SLSER+A++KG  
Sbjct: 184 MNPARSFGPAVVMNRFSPAHWVFWVGPIVGAVLAAILYFYLLFPNSLSLSERVAIIKGTY 243

Query: 241 EPDTDWEEREVRRRQSVEL 259
           EPD DWEE+   R++++EL
Sbjct: 244 EPDEDWEEQREERKKTMEL 262


>gi|6912506 major intrinsic protein of lens fiber [Homo sapiens]
          Length = 263

 Score =  326 bits (836), Expect = 1e-89
 Identities = 161/261 (61%), Positives = 206/261 (78%), Gaps = 1/261 (0%)

Query: 1   MWELRSIAFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALG 60
           MWELRS +F RA+FAEF ATL +VFFGLGS+L W      VLQ+AMAFGL + TLVQ++G
Sbjct: 1   MWELRSASFWRAIFAEFFATLFYVFFGLGSSLRWAPGPLHVLQVAMAFGLALATLVQSVG 60

Query: 61  HISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNA 120
           HISGAH+NPAVT A LVG  +S+LRA  Y+AAQLLGAVAGAA+L+ +TP  +RG+LA+N 
Sbjct: 61  HISGAHVNPAVTFAFLVGSQMSLLRAFCYMAAQLLGAVAGAAVLYSVTPPAVRGNLALNT 120

Query: 121 LSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTG 180
           L  + + GQA TVE+FLTLQ VLCIFA+ DERR    G+ AL++GFS+ALGHL G++YTG
Sbjct: 121 LHPAVSVGQATTVEIFLTLQFVLCIFATYDERRNGQLGSVALAVGFSLALGHLFGMYYTG 180

Query: 181 CSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGL 240
             MNPARS APA++TG F +HWV+W+GP++G  LGSLLY+++LFP  KS+SERL+VLKG 
Sbjct: 181 AGMNPARSFAPAILTGNFTNHWVYWVGPIIGGGLGSLLYDFLLFPRLKSISERLSVLKGA 240

Query: 241 EPDTDWEEREVRRRQSVELHS 261
           +PD    + EV   + VEL++
Sbjct: 241 KPDVSNGQPEV-TGEPVELNT 260


>gi|86792455 aquaporin 6 [Homo sapiens]
          Length = 282

 Score =  299 bits (765), Expect = 2e-81
 Identities = 148/232 (63%), Positives = 178/232 (76%), Gaps = 2/232 (0%)

Query: 8   AFSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHI 67
           A SRA+FAEFLAT L+VFFG+GS + WP ALPSVLQIA+ F L     VQ     SGAH 
Sbjct: 22  AISRALFAEFLATGLYVFFGVGSVMRWPTALPSVLQIAITFNLVTAMAVQVTWKASGAHA 81

Query: 68  NPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSNSTTA 127
           NPAVT+A LVG H+S+ RA  YVAAQL+GA  GAALL+ + P DIR  L +N + NS + 
Sbjct: 82  NPAVTLAFLVGSHISLPRAVAYVAAQLVGATVGAALLYGVMPGDIRETLGINVVRNSVST 141

Query: 128 GQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPAR 187
           GQAV VEL LTLQLVLC+FASTD R  +  G+PA  IG SVALGHL+GIH+TGCSMNPAR
Sbjct: 142 GQAVAVELLLTLQLVLCVFASTDSR--QTSGSPATMIGISVALGHLIGIHFTGCSMNPAR 199

Query: 188 SLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKG 239
           S  PA++ GKF  HWVFW+GPL+GA+L SL+YN+VLFP  K+L++RLA+L G
Sbjct: 200 SFGPAIIIGKFTVHWVFWVGPLMGALLASLIYNFVLFPDTKTLAQRLAILTG 251


>gi|4755125 aquaporin 4 isoform b [Homo sapiens]
          Length = 301

 Score =  233 bits (593), Expect = 2e-61
 Identities = 114/222 (51%), Positives = 154/222 (69%), Gaps = 4/222 (1%)

Query: 8   AFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQALGHIS 63
           AF +AV AEFLA L+FV   LGS +NW    + LP  ++ I++ FGL I T+VQ  GHIS
Sbjct: 11  AFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHIS 70

Query: 64  GAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSN 123
           G HINPAVTVA +    +S+ ++ FY+AAQ LGA+ GA +L+ +TP  + G L V  +  
Sbjct: 71  GGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHG 130

Query: 124 STTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSM 183
           + TAG  + VEL +T QLV  IFAS D +R +  G+ AL+IGFSVA+GHL  I+YTG SM
Sbjct: 131 NLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASM 190

Query: 184 NPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFP 225
           NPARS  PAV+ G +++HW++W+GP++GA+L   LY YV  P
Sbjct: 191 NPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 232


>gi|4502181 aquaporin 4 isoform a [Homo sapiens]
          Length = 323

 Score =  233 bits (593), Expect = 2e-61
 Identities = 114/222 (51%), Positives = 154/222 (69%), Gaps = 4/222 (1%)

Query: 8   AFSRAVFAEFLATLLFVFFGLGSALNW---PQALP-SVLQIAMAFGLGIGTLVQALGHIS 63
           AF +AV AEFLA L+FV   LGS +NW    + LP  ++ I++ FGL I T+VQ  GHIS
Sbjct: 33  AFWKAVTAEFLAMLIFVLLSLGSTINWGGTEKPLPVDMVLISLCFGLSIATMVQCFGHIS 92

Query: 64  GAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNALSN 123
           G HINPAVTVA +    +S+ ++ FY+AAQ LGA+ GA +L+ +TP  + G L V  +  
Sbjct: 93  GGHINPAVTVAMVCTRKISIAKSVFYIAAQCLGAIIGAGILYLVTPPSVVGGLGVTMVHG 152

Query: 124 STTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSM 183
           + TAG  + VEL +T QLV  IFAS D +R +  G+ AL+IGFSVA+GHL  I+YTG SM
Sbjct: 153 NLTAGHGLLVELIITFQLVFTIFASCDSKRTDVTGSIALAIGFSVAIGHLFAINYTGASM 212

Query: 184 NPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFP 225
           NPARS  PAV+ G +++HW++W+GP++GA+L   LY YV  P
Sbjct: 213 NPARSFGPAVIMGNWENHWIYWVGPIIGAVLAGGLYEYVFCP 254


>gi|37694062 aquaporin 1 [Homo sapiens]
          Length = 269

 Score =  230 bits (587), Expect = 9e-61
 Identities = 114/241 (47%), Positives = 159/241 (65%), Gaps = 7/241 (2%)

Query: 3   ELRSIAFSRAVFAEFLATLLFVFFGLGSAL-------NWPQALPSVLQIAMAFGLGIGTL 55
           E +   F RAV AEFLAT LFVF  +GSAL       N   A+   +++++AFGL I TL
Sbjct: 4   EFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATL 63

Query: 56  VQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGD 115
            Q++GHISGAH+NPAVT+  L+ C +S+ RA  Y+ AQ +GA+   A+L  IT +     
Sbjct: 64  AQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNS 123

Query: 116 LAVNALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLG 175
           L  N L++   +GQ + +E+  TLQLVLC+ A+TD RR +  G+  L+IG SVALGHLL 
Sbjct: 124 LGRNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLA 183

Query: 176 IHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLA 235
           I YTGC +NPARS   AV+T  F +HW+FW+GP +G  L  L+Y+++L P +  L++R+ 
Sbjct: 184 IDYTGCGINPARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVK 243

Query: 236 V 236
           V
Sbjct: 244 V 244


>gi|45446752 aquaporin 8 [Homo sapiens]
          Length = 261

 Score =  119 bits (299), Expect = 2e-27
 Identities = 74/214 (34%), Positives = 113/214 (52%), Gaps = 7/214 (3%)

Query: 9   FSRAVFAEFLATLLFVFFGLGSALNWPQALPSVLQIAMAFGLGIGTLVQALGHISGAHIN 68
           F +    E L + LF+F G  S +        +LQ A+A GL +G ++  LG+ISG H N
Sbjct: 34  FVQPCLVELLGSALFIFIGCLSVIE-NGTDTGLLQPALAHGLALGLVIATLGNISGGHFN 92

Query: 69  PAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPAD----IRGDLAVNALSNS 124
           PAV++A ++   ++++    Y  +QLLG + GAAL   ++P +      G   V      
Sbjct: 93  PAVSLAAMLIGGLNLVMLLPYWVSQLLGGMLGAALAKAVSPEERFWNASGAAFVTVQEQG 152

Query: 125 TTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHYTGCSMN 184
             AG A+  E+ LT  L L +       + + P  P  SIGF+V +  L G   +G  MN
Sbjct: 153 QVAG-ALVAEIILTTLLALAVCMGAINEKTKGPLAP-FSIGFAVTVDILAGGPVSGGCMN 210

Query: 185 PARSLAPAVVTGKFDDHWVFWIGPLVGAILGSLL 218
           PAR+  PAVV   ++ HW++W+GPL+  +L  LL
Sbjct: 211 PARAFGPAVVANHWNFHWIYWLGPLLAGLLVGLL 244


>gi|4502187 aquaporin 7 [Homo sapiens]
          Length = 342

 Score = 95.9 bits (237), Expect = 3e-20
 Identities = 85/240 (35%), Positives = 117/240 (48%), Gaps = 33/240 (13%)

Query: 11  RAVFAEFLATLLFVFFGLGSALNWP--QALPSVLQIAMAFGLGIGTLVQALGHISGAHIN 68
           R   AEF++T + + FGLGS  +    +   S L + + FG G+   V   G ISGAH+N
Sbjct: 35  REFLAEFMSTYVMMVFGLGSVAHMVLNKKYGSYLGVNLGFGFGVTMGVHVAGRISGAHMN 94

Query: 69  PAVTVA-CLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADI----RGDLAVNA--- 120
            AVT A C +G  V   +   YV  Q LG+   AA ++ +    I     G L V     
Sbjct: 95  AAVTFANCALG-RVPWRKFPVYVLGQFLGSFLAAATIYSLFYTAILHFSGGQLMVTGPVA 153

Query: 121 --------LSNSTTAGQAVTVELFLTLQLVLCIFASTD-ERRGENPGTPALSIGFSVA-L 170
                   L +  T  +    E +LT  L LC+FA TD E     PGT AL IG  V  +
Sbjct: 154 TAGIFATYLPDHMTLWRGFLNEAWLTGMLQLCLFAITDQENNPALPGTEALVIGILVVII 213

Query: 171 GHLLGIHYTGCSMNPARSLAPAVVT-----GK--FDD----HWVFWIGPLVGAILGSLLY 219
           G  LG++ TG ++NP+R L P + T     GK  F +     WV  + PL+GA LG ++Y
Sbjct: 214 GVSLGMN-TGYAINPSRDLPPRIFTFIAGWGKQVFSNGENWWWVPVVAPLLGAYLGGIIY 272


>gi|157266307 aquaporin 9 [Homo sapiens]
          Length = 295

 Score = 90.9 bits (224), Expect = 1e-18
 Identities = 75/251 (29%), Positives = 121/251 (48%), Gaps = 40/251 (15%)

Query: 8   AFSRAVFAEFLATLLFVFFGLGSALNWPQALPS------VLQIAMAFGLGIGTLVQALGH 61
           + ++   +EFL T + +  G G      QA+ S      V+ I + F + +   +   G 
Sbjct: 21  SLAKETLSEFLGTFILIVLGCGCVA---QAILSRGRFGGVITINVGFSMAVAMAIYVAGG 77

Query: 62  ISGAHINPAVTVA-CLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIR----GDL 116
           +SG HINPAV++A CL G  +   +  FYV AQ LGA  GAA +  I    +     G L
Sbjct: 78  VSGGHINPAVSLAMCLFG-RMKWFKLPFYVGAQFLGAFVGAATVFGIYYDGLMSFAGGKL 136

Query: 117 AV---NALSN--------STTAGQAVTVELFLTLQLVLCIFASTDERR-GENPGTPALSI 164
            +   NA ++          +   A   ++  T+ L++ +FA  D R  G   G   ++I
Sbjct: 137 LIVGENATAHIFATYPAPYLSLANAFADQVVATMILLIIVFAIFDSRNLGAPRGLEPIAI 196

Query: 165 G-FSVALGHLLGIHYTGCSMNPARSLAPAVVTGKF-----------DDHWVFWIGPLVGA 212
           G   + +   LG++ +GC+MNPAR L+P + T              +  W+  +GPLVGA
Sbjct: 197 GLLIIVIASSLGLN-SGCAMNPARDLSPRLFTALAGWGFEVFRAGNNFWWIPVVGPLVGA 255

Query: 213 ILGSLLYNYVL 223
           ++G L+Y  V+
Sbjct: 256 VIGGLIYVLVI 266


>gi|4826645 aquaporin 3 [Homo sapiens]
          Length = 292

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 71/246 (28%), Positives = 105/246 (42%), Gaps = 36/246 (14%)

Query: 11  RAVFAEFLATLLFVFFGLGSALNWPQALPS---VLQIAMAFGLGIGTLVQALGHISGAHI 67
           R   AE L TL+ V FG GS      +  +    L I +AFG  +   +   G +SGAH+
Sbjct: 23  RQALAECLGTLILVMFGCGSVAQVVLSRGTHGGFLTINLAFGFAVTLGILIAGQVSGAHL 82

Query: 68  NPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITPADIRGDLAVNAL---SNS 124
           NPAVT A         ++   Y  AQ LGA  GA ++  +   D     A N L     +
Sbjct: 83  NPAVTFAMCFLAREPWIKLPIYTLAQTLGAFLGAGIVFGLY-YDAIWHFADNQLFVSGPN 141

Query: 125 TTAGQAVTV-------------ELFLTLQLVLCIFASTDERRGENP-GTPALSIGFSV-A 169
            TAG   T              +   T  L++C+ A  D      P G  A ++G  V  
Sbjct: 142 GTAGIFATYPSGHLDMINGFFDQFIGTASLIVCVLAIVDPYNNPVPRGLEAFTVGLVVLV 201

Query: 170 LGHLLGIHYTGCSMNPARSLAPAVVTG---------KFDDHWVFW---IGPLVGAILGSL 217
           +G  +G + +G ++NPAR   P + T              HW +W   + PL+G+I G  
Sbjct: 202 IGTSMGFN-SGYAVNPARDFGPRLFTALAGWGSAVFTTGQHW-WWVPIVSPLLGSIAGVF 259

Query: 218 LYNYVL 223
           +Y  ++
Sbjct: 260 VYQLMI 265


>gi|22538420 aquaporin 10 [Homo sapiens]
          Length = 301

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 62/252 (24%), Positives = 108/252 (42%), Gaps = 35/252 (13%)

Query: 4   LRSIAFSRAVFAEFLATLLFVFFGLGS---ALNWPQALPSVLQIAMAFGLGIGTLVQALG 60
           +RS+  +R   AEFL   + +    G+   A+   +   +   + +A  L +   +   G
Sbjct: 16  IRSL-LARQCLAEFLGVFVLMLLTQGAVAQAVTSGETKGNFFTMFLAGSLAVTIAIYVGG 74

Query: 61  HISGAHINPAVTVA-CLVGCHVSVLRAAFYVAAQLLGAVAGA----ALLHEITPADIRGD 115
           ++SGAH+NPA ++A C+VG  +  ++   Y+  QLL A   +     L H+       G+
Sbjct: 75  NVSGAHLNPAFSLAMCIVG-RLPWVKLPIYILVQLLSAFCASGATYVLYHDALQNYTGGN 133

Query: 116 LAVNALSNST-----------TAGQAVTVELFLTLQLVLCIFASTDER-RGENPGTPALS 163
           L V     +            +       ++  T  L++ + A  D R +G   G   + 
Sbjct: 134 LTVTGPKETASIFATYPAPYLSLNNGFLDQVLGTGMLIVGLLAILDRRNKGVPAGLEPVV 193

Query: 164 IGFSV-ALGHLLGIHYTGCSMNPARSLAPAVVT-----------GKFDDHWVFWIGPLVG 211
           +G  + ALG  +G +  G  +NPAR L P + T                 WV  + PLVG
Sbjct: 194 VGMLILALGLSMGAN-CGIPLNPARDLGPRLFTYVAGWGPEVFSAGNGWWWVPVVAPLVG 252

Query: 212 AILGSLLYNYVL 223
           A +G+  Y  ++
Sbjct: 253 ATVGTATYQLLV 264


>gi|40538880 aquaporin 12A [Homo sapiens]
          Length = 295

 Score = 34.3 bits (77), Expect = 0.12
 Identities = 39/167 (23%), Positives = 63/167 (37%), Gaps = 12/167 (7%)

Query: 62  ISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITP---ADIRGDLAV 118
           + GA  NP V++   +    S+      +AAQ LG  A   L+        +D+    ++
Sbjct: 75  LDGASANPTVSLQEFLMAEQSLPGTLLKLAAQGLGMQAACTLMRLCWAWELSDLHLLQSL 134

Query: 119 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHY 178
            A S S+    +V     +      C   +    R   P     ++   V +       +
Sbjct: 135 MAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPF 194

Query: 179 TGCSMNPARSLAPAVVTGKFDDHW------VFWIGPLVGAILGSLLY 219
           T    NPA +   A VT     H       V+W+GPL G +L  LL+
Sbjct: 195 TSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 238


>gi|156447037 aquaporin 12B [Homo sapiens]
          Length = 307

 Score = 33.1 bits (74), Expect = 0.26
 Identities = 39/167 (23%), Positives = 62/167 (37%), Gaps = 12/167 (7%)

Query: 62  ISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGAVAGAALLHEITP---ADIRGDLAV 118
           + GA  NP V++   +    S+      +AAQ LG  A   L         +D+    ++
Sbjct: 87  LDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAACTLTRLCWAWELSDLHLLQSL 146

Query: 119 NALSNSTTAGQAVTVELFLTLQLVLCIFASTDERRGENPGTPALSIGFSVALGHLLGIHY 178
            A S S+    +V     +      C   +    R   P     ++   V +       +
Sbjct: 147 MAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAYSGPAVALLVTVTAYTAGPF 206

Query: 179 TGCSMNPARSLAPAVVTGKFDDHW------VFWIGPLVGAILGSLLY 219
           T    NPA +   A VT     H       V+W+GPL G +L  LL+
Sbjct: 207 TSAFFNPALA---ASVTFACSGHTLLEYVQVYWLGPLTGMVLAVLLH 250


>gi|83921614 cytochrome b5 outer mitochondrial membrane precursor
           [Homo sapiens]
          Length = 150

 Score = 30.8 bits (68), Expect = 1.3
 Identities = 10/20 (50%), Positives = 14/20 (70%)

Query: 202 WVFWIGPLVGAILGSLLYNY 221
           W +WI P++GA+L   LY Y
Sbjct: 123 WAYWILPIIGAVLLGFLYRY 142


>gi|188528618 solute carrier family 6 (neurotransmitter transporter,
           GABA), member 1 [Homo sapiens]
          Length = 599

 Score = 29.6 bits (65), Expect = 2.9
 Identities = 16/45 (35%), Positives = 26/45 (57%), Gaps = 4/45 (8%)

Query: 38  LPSVLQIAMAFGLGIGTLVQALGHISGAHIN---PAVTVACLVGC 79
           L +  QI  ++GLG+G+L+ ALG  +  H N    ++ V C+  C
Sbjct: 286 LDAATQIFFSYGLGLGSLI-ALGSYNSFHNNVYRDSIIVCCINSC 329


>gi|185136021 spinster homolog 2 [Homo sapiens]
          Length = 549

 Score = 29.3 bits (64), Expect = 3.8
 Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 14/75 (18%)

Query: 155 ENPGTPALSIG-FSVALGHLLGIHYTGCSMNPARSLAPAVVTGKFDDHWVFWIGPLVGAI 213
           +N  T  LS+  F++ LG  LG + TG S+  A            D HW   + P++G I
Sbjct: 224 KNTRTLMLSVFYFAIPLGSGLG-YITGSSVKQAAG----------DWHWALRVSPVLGMI 272

Query: 214 LGSLLYNYVLFPPAK 228
            G+L+   +L P  K
Sbjct: 273 TGTLI--LILVPATK 285


>gi|169168886 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 278

 Score = 28.9 bits (63), Expect = 5.0
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 10/65 (15%)

Query: 45  AMAFGLG-IGTLVQALGHISGAHINPAVTVACLVGCHVSVLRAAFYVAAQLLGA--VAGA 101
           A++F  G +G   +A GH+       AV  A L G H  +        AQLLGA   A A
Sbjct: 92  AVSFSSGRVGVREEAAGHL-------AVGAAGLTGAHADLAVGRGAELAQLLGADAAAAA 144

Query: 102 ALLHE 106
           A+ HE
Sbjct: 145 AVQHE 149


>gi|239752881 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 254

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 12/124 (9%)

Query: 150 DERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAV----VTGKFD-DHWVF 204
           DER  E PG   +++G  ++L     +H     + P   L P      +T   D DH   
Sbjct: 99  DERAVEGPGDSKVTVGNILSLQDASELHRLAHRVQPLLCLQPNSEFFGLTSWLDVDHGS- 157

Query: 205 WIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQS 264
            +G L G    S+     +  P   L+   A+++ L+ +    E E    Q V+ H PQ+
Sbjct: 158 -LGTLSG---HSIPRPIRILDPLGGLAVEFALVRRLQVEDG--EAEGGPPQLVQPHLPQA 211

Query: 265 LPRG 268
           LP G
Sbjct: 212 LPLG 215


>gi|239747434 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 254

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 12/124 (9%)

Query: 150 DERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAV----VTGKFD-DHWVF 204
           DER  E PG   +++G  ++L     +H     + P   L P      +T   D DH   
Sbjct: 99  DERAVEGPGDSKVTVGNILSLQDASELHRLAHRVQPLLCLQPNSEFFGLTSWLDVDHGS- 157

Query: 205 WIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQS 264
            +G L G    S+     +  P   L+   A+++ L+ +    E E    Q V+ H PQ+
Sbjct: 158 -LGTLSG---HSIPRPIRILDPLGGLAVEFALVRRLQVEDG--EAEGGPPQLVQPHLPQA 211

Query: 265 LPRG 268
           LP G
Sbjct: 212 LPLG 215


>gi|239741258 PREDICTED: hypothetical protein XP_002342146 [Homo
           sapiens]
          Length = 254

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 12/124 (9%)

Query: 150 DERRGENPGTPALSIGFSVALGHLLGIHYTGCSMNPARSLAPAV----VTGKFD-DHWVF 204
           DER  E PG   +++G  ++L     +H     + P   L P      +T   D DH   
Sbjct: 99  DERAVEGPGDSKVTVGNILSLQDASELHRLAHRVQPLLCLQPNSEFFGLTSWLDVDHGS- 157

Query: 205 WIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEEREVRRRQSVELHSPQS 264
            +G L G    S+     +  P   L+   A+++ L+ +    E E    Q V+ H PQ+
Sbjct: 158 -LGTLSG---HSIPRPIRILDPLGGLAVEFALVRRLQVEDG--EAEGGPPQLVQPHLPQA 211

Query: 265 LPRG 268
           LP G
Sbjct: 212 LPLG 215


>gi|215490100 spinster homolog 1 isoform 2 [Homo sapiens]
          Length = 455

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 199 DDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEE-REVRRRQSV 257
           D HW   + P +G +   LL+  V  PP +   ER + L  L P + W + R + R  S 
Sbjct: 142 DWHWALRVTPGLGVVAVLLLFLVVREPP-RGAVERHSDLPPLNPTSWWADLRALARNPSF 200

Query: 258 ELHS 261
            L S
Sbjct: 201 VLSS 204


>gi|215490096 spinster homolog 1 isoform 1 [Homo sapiens]
          Length = 528

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 199 DDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEE-REVRRRQSV 257
           D HW   + P +G +   LL+  V  PP +   ER + L  L P + W + R + R  S 
Sbjct: 215 DWHWALRVTPGLGVVAVLLLFLVVREPP-RGAVERHSDLPPLNPTSWWADLRALARNPSF 273

Query: 258 ELHS 261
            L S
Sbjct: 274 VLSS 277


>gi|14042968 spinster homolog 1 isoform 1 [Homo sapiens]
          Length = 528

 Score = 28.5 bits (62), Expect = 6.5
 Identities = 21/64 (32%), Positives = 30/64 (46%), Gaps = 2/64 (3%)

Query: 199 DDHWVFWIGPLVGAILGSLLYNYVLFPPAKSLSERLAVLKGLEPDTDWEE-REVRRRQSV 257
           D HW   + P +G +   LL+  V  PP +   ER + L  L P + W + R + R  S 
Sbjct: 215 DWHWALRVTPGLGVVAVLLLFLVVREPP-RGAVERHSDLPPLNPTSWWADLRALARNPSF 273

Query: 258 ELHS 261
            L S
Sbjct: 274 VLSS 277


>gi|47933389 solute carrier family 2, member 9 protein isoform 2
           [Homo sapiens]
          Length = 511

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 18/93 (19%)

Query: 40  SVLQIAMAFGLGIGTL-VQALGHISG------AHINPAVTVACLVGCHVSVLRAAF---Y 89
           SV     A G  +GTL V+ +G + G      A+   A++ A L+ C  S+   AF    
Sbjct: 82  SVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMAC--SLQAGAFEMLI 139

Query: 90  VAAQLLGAVAGAAL------LHEITPADIRGDL 116
           V   ++G   G AL      L EI+P +IRG L
Sbjct: 140 VGRFIMGIDGGVALSVLPMYLSEISPKEIRGSL 172


>gi|47933387 solute carrier family 2, member 9 protein isoform 1
           [Homo sapiens]
          Length = 540

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 18/93 (19%)

Query: 40  SVLQIAMAFGLGIGTL-VQALGHISG------AHINPAVTVACLVGCHVSVLRAAF---Y 89
           SV     A G  +GTL V+ +G + G      A+   A++ A L+ C  S+   AF    
Sbjct: 111 SVTVSIFAIGGLVGTLIVKMIGKVLGRKHTLLANNGFAISAALLMAC--SLQAGAFEMLI 168

Query: 90  VAAQLLGAVAGAAL------LHEITPADIRGDL 116
           V   ++G   G AL      L EI+P +IRG L
Sbjct: 169 VGRFIMGIDGGVALSVLPMYLSEISPKEIRGSL 201


>gi|24497589 aristaless related homeobox [Homo sapiens]
          Length = 562

 Score = 28.1 bits (61), Expect = 8.5
 Identities = 23/69 (33%), Positives = 33/69 (47%), Gaps = 5/69 (7%)

Query: 63  SGAHINPAVTVACLVGCHVSVLRAAF----YVAAQLLGAVAGAALLHEITPADIRGDLAV 118
           SGA +  +  +   V  H + +  AF       A L  A   AALL + TPA + G +A 
Sbjct: 456 SGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTPA-VEGAVAS 514

Query: 119 NALSNSTTA 127
            AL++  TA
Sbjct: 515 GALADPATA 523


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.138    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,589,856
Number of Sequences: 37866
Number of extensions: 391717
Number of successful extensions: 1229
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1190
Number of HSP's gapped (non-prelim): 27
length of query: 271
length of database: 18,247,518
effective HSP length: 101
effective length of query: 170
effective length of database: 14,423,052
effective search space: 2451918840
effective search space used: 2451918840
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.5 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.