Guide to the Human Genome
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Search of human proteins with 4502141

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
sapiens]
         (618 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo sap...  1266   0.0  
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa...   907   0.0  
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap...   907   0.0  
gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo sa...   282   6e-76
gi|119393878 NLR family, apoptosis inhibitory protein isoform 1 ...   159   6e-39
gi|44680139 baculoviral IAP repeat-containing 8 [Homo sapiens]        119   1e-26
gi|11545910 livin inhibitor of apoptosis isoform beta [Homo sapi...   112   1e-24
gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo sap...   112   1e-24
gi|119393876 NLR family, apoptosis inhibitory protein isoform 2 ...    75   2e-13
gi|38788243 myosin regulatory light chain interacting protein [H...    67   5e-11
gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens]        63   9e-10
gi|62865649 rififylin [Homo sapiens]                                   60   5e-09
gi|17432433 rififylin [Homo sapiens]                                   60   5e-09
gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]            57   5e-08
gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]            57   5e-08
gi|30348954 mindbomb homolog 1 [Homo sapiens]                          56   1e-07
gi|53729363 leucine rich repeat and sterile alpha motif containi...    55   2e-07
gi|53729361 leucine rich repeat and sterile alpha motif containi...    55   2e-07
gi|53729359 leucine rich repeat and sterile alpha motif containi...    55   2e-07
gi|59859878 baculoviral IAP repeat-containing protein 5 isoform ...    52   1e-06
gi|21264330 mindbomb homolog 2 [Homo sapiens]                          50   5e-06
gi|14042925 ring finger protein 26 [Homo sapiens]                      50   5e-06
gi|47716512 mex-3 homolog B [Homo sapiens]                             49   1e-05
gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]    49   1e-05
gi|217416388 neuralized homolog 1B [Homo sapiens]                      47   4e-05
gi|5729765 cell growth regulator with ring finger domain 1 [Homo...    47   5e-05
gi|223278368 neuralized-like [Homo sapiens]                            46   9e-05
gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1 ...    46   9e-05
gi|147902746 MEX3A protein [Homo sapiens]                              46   9e-05
gi|40788015 caspase recruitment domain protein 12 [Homo sapiens]       45   2e-04

>gi|4502141 baculoviral IAP repeat-containing protein 2 [Homo
           sapiens]
          Length = 618

 Score = 1266 bits (3277), Expect = 0.0
 Identities = 618/618 (100%), Positives = 618/618 (100%)

Query: 1   MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV 60
           MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV
Sbjct: 1   MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV 60

Query: 61  PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS 120
           PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS
Sbjct: 61  PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS 120

Query: 121 LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA 180
           LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA
Sbjct: 121 LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA 180

Query: 181 MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH 240
           MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH
Sbjct: 181 MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH 240

Query: 241 RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR 300
           RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR
Sbjct: 241 RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR 300

Query: 301 NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL 360
           NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL
Sbjct: 301 NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL 360

Query: 361 STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT 420
           STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT
Sbjct: 361 STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT 420

Query: 421 GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD 480
           GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD
Sbjct: 421 GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD 480

Query: 481 NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF 540
           NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF
Sbjct: 481 NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF 540

Query: 541 VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR 600
           VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR
Sbjct: 541 VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR 600

Query: 601 KCPICRGIIKGTVRTFLS 618
           KCPICRGIIKGTVRTFLS
Sbjct: 601 KCPICRGIIKGTVRTFLS 618


>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score =  907 bits (2345), Expect = 0.0
 Identities = 438/603 (72%), Positives = 509/603 (84%), Gaps = 4/603 (0%)

Query: 20  SIMEDSTILSDWTNS-NKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN 78
           +I+E+S  LS+   S N  ++KYD SCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN
Sbjct: 2   NIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN 61

Query: 79  DKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS-LGSTSKNTSPMR-NSFA 136
           DKVKCFCCGLMLDNWK GDSP +KHK+LYPSC F+Q+L S + L +TS+ T P    +  
Sbjct: 62  DKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNST 121

Query: 137 HSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPL 196
           HSL P  E+S  F GSYS+   NP+NSRA +D S+   + Y  AM+ E AR LT+  WPL
Sbjct: 122 HSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPL 181

Query: 197 TFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLE- 255
           TFLSP++LA+AGFYYIGPGDRVACFACGGKLSNWEPKD+AMSEH RHFP CPF+EN L+ 
Sbjct: 182 TFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQD 241

Query: 256 TLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRC 315
           T R+++SNLSMQTHAAR +TF  WPSSV V PEQLASAGFYYVG +DDVKCFCCDGGLRC
Sbjct: 242 TSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRC 301

Query: 316 WESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPI 375
           WESGDDPWV+HAKWFPRCE+LIR+KGQEF+ ++Q  YPHLLEQLLSTSD+ G+ENA+  I
Sbjct: 302 WESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSI 361

Query: 376 IHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALL 435
           IHF PGE  SEDA+MMNTPV+ +A+EMGF+R LVKQTVQ KIL TGENY+ VND+V  LL
Sbjct: 362 IHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLL 421

Query: 436 NAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDI 495
           NAEDE REEE+E+  EE  S+DL LIRKNRMALFQ LTCV+PILD+LL A +IN+QEHD+
Sbjct: 422 NAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDV 481

Query: 496 IKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSG 555
           IKQKTQ  LQARELIDTILVKGN AA +F+N L+E ++ LY++LFV +++KYIPTEDVS 
Sbjct: 482 IKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSD 541

Query: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRT 615
           L +EEQLRRLQEERTCKVCMDKEVS+VFIPCGHLVVC++CAPSLRKCPICR  IKGTVRT
Sbjct: 542 LPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRT 601

Query: 616 FLS 618
           FLS
Sbjct: 602 FLS 604


>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
           sapiens]
          Length = 604

 Score =  907 bits (2345), Expect = 0.0
 Identities = 438/603 (72%), Positives = 509/603 (84%), Gaps = 4/603 (0%)

Query: 20  SIMEDSTILSDWTNS-NKQKMKYDFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN 78
           +I+E+S  LS+   S N  ++KYD SCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN
Sbjct: 2   NIVENSIFLSNLMKSANTFELKYDLSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVN 61

Query: 79  DKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS-LGSTSKNTSPMR-NSFA 136
           DKVKCFCCGLMLDNWK GDSP +KHK+LYPSC F+Q+L S + L +TS+ T P    +  
Sbjct: 62  DKVKCFCCGLMLDNWKRGDSPTEKHKKLYPSCRFVQSLNSVNNLEATSQPTFPSSVTNST 121

Query: 137 HSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPL 196
           HSL P  E+S  F GSYS+   NP+NSRA +D S+   + Y  AM+ E AR LT+  WPL
Sbjct: 122 HSLLPGTENSGYFRGSYSNSPSNPVNSRANQDFSALMRSSYHCAMNNENARLLTFQTWPL 181

Query: 197 TFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLE- 255
           TFLSP++LA+AGFYYIGPGDRVACFACGGKLSNWEPKD+AMSEH RHFP CPF+EN L+ 
Sbjct: 182 TFLSPTDLAKAGFYYIGPGDRVACFACGGKLSNWEPKDNAMSEHLRHFPKCPFIENQLQD 241

Query: 256 TLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRC 315
           T R+++SNLSMQTHAAR +TF  WPSSV V PEQLASAGFYYVG +DDVKCFCCDGGLRC
Sbjct: 242 TSRYTVSNLSMQTHAARFKTFFNWPSSVLVNPEQLASAGFYYVGNSDDVKCFCCDGGLRC 301

Query: 316 WESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPI 375
           WESGDDPWV+HAKWFPRCE+LIR+KGQEF+ ++Q  YPHLLEQLLSTSD+ G+ENA+  I
Sbjct: 302 WESGDDPWVQHAKWFPRCEYLIRIKGQEFIRQVQASYPHLLEQLLSTSDSPGDENAESSI 361

Query: 376 IHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALL 435
           IHF PGE  SEDA+MMNTPV+ +A+EMGF+R LVKQTVQ KIL TGENY+ VND+V  LL
Sbjct: 362 IHFEPGEDHSEDAIMMNTPVINAAVEMGFSRSLVKQTVQRKILATGENYRLVNDLVLDLL 421

Query: 436 NAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILDNLLKANVINKQEHDI 495
           NAEDE REEE+E+  EE  S+DL LIRKNRMALFQ LTCV+PILD+LL A +IN+QEHD+
Sbjct: 422 NAEDEIREEERERATEEKESNDLLLIRKNRMALFQHLTCVIPILDSLLTAGIINEQEHDV 481

Query: 496 IKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLFVDKNMKYIPTEDVSG 555
           IKQKTQ  LQARELIDTILVKGN AA +F+N L+E ++ LY++LFV +++KYIPTEDVS 
Sbjct: 482 IKQKTQTSLQARELIDTILVKGNIAATVFRNSLQEAEAVLYEHLFVQQDIKYIPTEDVSD 541

Query: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRT 615
           L +EEQLRRLQEERTCKVCMDKEVS+VFIPCGHLVVC++CAPSLRKCPICR  IKGTVRT
Sbjct: 542 LPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPICRSTIKGTVRT 601

Query: 616 FLS 618
           FLS
Sbjct: 602 FLS 604


>gi|32528299 baculoviral IAP repeat-containing protein 4 [Homo
           sapiens]
          Length = 497

 Score =  282 bits (722), Expect = 6e-76
 Identities = 164/447 (36%), Positives = 243/447 (54%), Gaps = 41/447 (9%)

Query: 42  DFSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQ 101
           +F  E  R+ T++ FP+G PVS  +LARAGF YTG  D V+CF C   +D W+ GDS + 
Sbjct: 22  EFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVG 81

Query: 102 KHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSF-AHSLSPTLEHSSLFSGSYSSLSPNP 160
           +H+++ P+C FI      +  + S N+      +   +   + +H +L   S +  +   
Sbjct: 82  RHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETH-ADYL 140

Query: 161 LNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWP-LTFLSPSELARAGFYYIGPGDRVA 219
           L +  V DIS +   P + AM +EEAR  ++  WP    L+P ELA AG YY G GD+V 
Sbjct: 141 LRTGQVVDISDT-IYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQ 199

Query: 220 CFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENSLETLRFSIS----------------N 263
           CF CGGKL NWEP D A SEHRRHFPNC F+      +R                    N
Sbjct: 200 CFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRN 259

Query: 264 LSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPW 323
            SM  + AR+ TF  W  SV    EQLA AGFY +G  D VKCF C GGL  W+  +DPW
Sbjct: 260 PSMADYEARIFTFGTWIYSV--NKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPW 317

Query: 324 VEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQ-LLSTSDTTGEENADPPIIHFGPGE 382
            +HAKW+P C++L+  KGQE+++ I     H LE+ L+ T++ T             P  
Sbjct: 318 EQHAKWYPGCKYLLEQKGQEYINNI--HLTHSLEECLVRTTEKT-------------PSL 362

Query: 383 SSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKR 442
           +   D  +   P+V+ A+ MGF+   +K+ ++ KI  +G NYK++  +V+ L+NA+ +  
Sbjct: 363 TRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSM 422

Query: 443 EEEKEK---QAEEMASDDLSLIRKNRM 466
           ++E  +   Q E    + L  +++ ++
Sbjct: 423 QDESSQTSLQKEISTEEQLRRLQEEKL 449



 Score = 87.4 bits (215), Expect = 3e-17
 Identities = 34/63 (53%), Positives = 50/63 (79%)

Query: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRT 615
           +S EEQLRRLQEE+ CK+CMD+ +++VF+PCGHLV C++CA ++ KCP+C  +I    + 
Sbjct: 435 ISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKI 494

Query: 616 FLS 618
           F+S
Sbjct: 495 FMS 497



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 48/153 (31%), Positives = 71/153 (46%), Gaps = 11/153 (7%)

Query: 17  NIKSIMEDSTILSDWTNSNKQKMKYDFSCELY--RMSTYSTFPAGVPVSERSLARAGFYY 74
           NI+S  E   + SD    N   +  + S   Y  R+ T+ T+   V  ++  LARAGFY 
Sbjct: 236 NIRS--ESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSV--NKEQLARAGFYA 291

Query: 75  TGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNS 134
            G  DKVKCF CG  L +WK  + P ++H + YP C ++        G    N   + +S
Sbjct: 292 LGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLE----QKGQEYINNIHLTHS 347

Query: 135 FAHSLSPTLEHS-SLFSGSYSSLSPNPLNSRAV 166
               L  T E + SL      ++  NP+   A+
Sbjct: 348 LEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAI 380


>gi|119393878 NLR family, apoptosis inhibitory protein isoform 1
           [Homo sapiens]
          Length = 1403

 Score =  159 bits (403), Expect = 6e-39
 Identities = 113/367 (30%), Positives = 158/367 (43%), Gaps = 76/367 (20%)

Query: 46  ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ 105
           E  R+ T+ T+        + +A AGFY+TGV   ++CFCC L+L    L   PI+ HK+
Sbjct: 60  EAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKR 119

Query: 106 LYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRA 165
            +P C F+ N     +G+ +K    ++N                                
Sbjct: 120 FHPDCGFLLN---KDVGNIAKYDIRVKNL------------------------------- 145

Query: 166 VEDISSSRTNPYSYAMSTEEARFLTYHMWPLTF--LSPSELARAGFYYIGPGDRVACFAC 223
                 SR          EEAR  ++  WP     +SP  L+ AGF + G  D V CF+C
Sbjct: 146 -----KSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSC 200

Query: 224 GGKLSNWEPKDDAMSEHRRHFPNCPFL---ENSLETLRFSIS------------------ 262
           GG L NWE  DD   EH + FP C FL   ++S E  ++  S                  
Sbjct: 201 GGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYIQSYKGFVDITGEHFVNSWVQ 260

Query: 263 -NLSMQT----------HAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDG 311
             L M +             R+ +F  WP    V    LA AG +Y G  D V+CF C G
Sbjct: 261 RELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGG 320

Query: 312 GLRCWESGDDPWVEHAKWFPRCEFLIRMKGQ-EFVDEIQGRYPHLLEQLLSTSDTTGEEN 370
            L  W+ GDDP  +H + FP C FL  MK   E   ++Q R   L E L +TS++  E++
Sbjct: 321 CLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQSR-GELCELLETTSESNLEDS 379

Query: 371 -ADPPII 376
            A  PI+
Sbjct: 380 IAVGPIV 386



 Score =  118 bits (296), Expect = 1e-26
 Identities = 72/207 (34%), Positives = 98/207 (47%), Gaps = 22/207 (10%)

Query: 177 YSYAMSTEEARFLTYHMW-PLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDD 235
           Y+  M +E  R  T+  + P +   P E+A AGFY+ G    + CF C   L        
Sbjct: 53  YNSQMRSEAKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRL 112

Query: 236 AMSEHRRHFPNCPFLEN----SLETLRFSISNLSM---------QTHAARMRTFMYWPSS 282
            + +H+R  P+C FL N    ++      + NL           Q   AR+ +F  WP  
Sbjct: 113 PIEDHKRFHPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFY 172

Query: 283 VP-VQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKG 341
           V  + P  L+ AGF + G+ D V+CF C G L  WE GDDPW EHAKWFP+CEFL   K 
Sbjct: 173 VQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKS 232

Query: 342 QEFVDEIQGRYPHLLEQLLSTSDTTGE 368
            E + +    Y   +       D TGE
Sbjct: 233 SEEITQYIQSYKGFV-------DITGE 252



 Score =  114 bits (286), Expect = 2e-25
 Identities = 69/217 (31%), Positives = 107/217 (49%), Gaps = 24/217 (11%)

Query: 38  KMKYDFSCELYRMSTYSTFPAGVP-VSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLG 96
           KM+Y    E  R++++  +P  V  +S   L+ AGF +TG  D V+CF CG  L NW+ G
Sbjct: 153 KMRYQE--EEARLASFRNWPFYVQGISPCVLSEAGFVFTGKQDTVQCFSCGGCLGNWEEG 210

Query: 97  DSPIQKHKQLYPSCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSL 156
           D P ++H + +P C F++          SK +S     +  S          + G     
Sbjct: 211 DDPWKEHAKWFPKCEFLR----------SKKSSEEITQYIQS----------YKGFVDIT 250

Query: 157 SPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMWPL-TFLSPSELARAGFYYIGPG 215
             + +NS    ++  +         + EE R  ++  WP  + +  + LA+AG +Y G  
Sbjct: 251 GEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIK 310

Query: 216 DRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLEN 252
           D V CF+CGG L  W+  DD + +H R FPNCPFL+N
Sbjct: 311 DIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQN 347



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 30/78 (38%), Positives = 50/78 (64%)

Query: 43  FSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQK 102
           F+ E  R+ ++  +P    V   +LA+AG +YTG+ D V+CF CG  L+ W+ GD P+  
Sbjct: 275 FAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDD 334

Query: 103 HKQLYPSCSFIQNLVSAS 120
           H + +P+C F+QN+ S++
Sbjct: 335 HTRCFPNCPFLQNMKSSA 352


>gi|44680139 baculoviral IAP repeat-containing 8 [Homo sapiens]
          Length = 236

 Score =  119 bits (297), Expect = 1e-26
 Identities = 64/180 (35%), Positives = 100/180 (55%), Gaps = 16/180 (8%)

Query: 266 MQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVE 325
           M  + AR+ TF  W  SV    EQLA AGFY +G+ D V+CF C GGL  W+  +DPW +
Sbjct: 1   MTGYEARLITFGTWMYSV--NKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQ 58

Query: 326 HAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPIIHFGPGESSS 385
           HAKW+P C++L+  KG E+++ I     HL   L      T ++          P  +  
Sbjct: 59  HAKWYPGCKYLLEEKGHEYINNI-----HLTRSLEGALVQTTKKT---------PSLTKR 104

Query: 386 EDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEE 445
               +   P+++ A+ MGF+   VK+ ++ +I T+G NYKT+  +V+ L++A+ +  E E
Sbjct: 105 ISDTIFPNPMLQEAIRMGFDFKDVKKIMEERIQTSGSNYKTLEVLVADLVSAQKDTTENE 164



 Score = 86.7 bits (213), Expect = 6e-17
 Identities = 35/63 (55%), Positives = 49/63 (77%)

Query: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRT 615
           +S EE LRRLQEE+ CK+CMD+ ++VVFIPCGHLV C++CA ++ +CP+C  +I    R 
Sbjct: 174 ISPEEPLRRLQEEKLCKICMDRHIAVVFIPCGHLVTCKQCAEAVDRCPMCSAVIDFKQRV 233

Query: 616 FLS 618
           F+S
Sbjct: 234 FMS 236



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 32/70 (45%), Positives = 47/70 (67%), Gaps = 1/70 (1%)

Query: 181 MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH 240
           M+  EAR +T+  W  + ++  +LARAGFY IG  D+V CF CGG L+NW+PK+D   +H
Sbjct: 1   MTGYEARLITFGTWMYS-VNKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQH 59

Query: 241 RRHFPNCPFL 250
            + +P C +L
Sbjct: 60  AKWYPGCKYL 69



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 39/119 (32%), Positives = 59/119 (49%), Gaps = 7/119 (5%)

Query: 49  RMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYP 108
           R+ T+ T+   V  ++  LARAGFY  G  DKV+CF CG  L NWK  + P ++H + YP
Sbjct: 7   RLITFGTWMYSV--NKEQLARAGFYAIGQEDKVQCFHCGGGLANWKPKEDPWEQHAKWYP 64

Query: 109 SCSFIQNLVSASLGSTSKNTSPMRNSFAHSLSPTLEHS-SLFSGSYSSLSPNPLNSRAV 166
            C ++        G    N   +  S   +L  T + + SL      ++ PNP+   A+
Sbjct: 65  GCKYLLE----EKGHEYINNIHLTRSLEGALVQTTKKTPSLTKRISDTIFPNPMLQEAI 119


>gi|11545910 livin inhibitor of apoptosis isoform beta [Homo
           sapiens]
          Length = 280

 Score =  112 bits (279), Expect = 1e-24
 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 4/138 (2%)

Query: 266 MQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVE 325
           M +   R+ +F  WP +  V PE LA+AGF++ G  D V+CF C GGL+ W+ GDDPW E
Sbjct: 84  MGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTE 143

Query: 326 HAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPIIHFGPGESSS 385
           HAKWFP C+FL+R KG++FV  +Q  +     QLL + D   E     P+    P     
Sbjct: 144 HAKWFPSCQFLLRSKGRDFVHSVQETH----SQLLGSWDPWEEPEDAAPVAPSVPASGYP 199

Query: 386 EDAVMMNTPVVKSALEMG 403
           E          +SA E G
Sbjct: 200 ELPTPRREVQSESAQEPG 217



 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 43/61 (70%), Positives = 51/61 (83%), Gaps = 1/61 (1%)

Query: 558 LEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFL 617
           +E QLRRLQEERTCKVC+D+ VS+VF+PCGHL VC ECAP L+ CPICR  ++  VRTFL
Sbjct: 221 VEAQLRRLQEERTCKVCLDRAVSIVFVPCGHL-VCAECAPGLQLCPICRAPVRSRVRTFL 279

Query: 618 S 618
           S
Sbjct: 280 S 280



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 65/222 (29%), Positives = 94/222 (42%), Gaps = 32/222 (14%)

Query: 76  GVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLG-STSKNTSPMRNS 134
           G  D  KC   G    +W  GD P Q+       C   ++L S  LG  T +    +   
Sbjct: 2   GPKDSAKCLHRGPQPSHWAAGDGPTQER------CG-PRSLGSPVLGLDTCRAWDHVDGQ 54

Query: 135 FAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMW 194
               L P  E      G+ ++LS  P                    M +EE R  +++ W
Sbjct: 55  ILGQLRPLTEEEEE-EGAGATLSRGPAFP----------------GMGSEELRLASFYDW 97

Query: 195 PLTFLSPSEL-ARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENS 253
           PLT   P EL A AGF++ G  D+V CF C G L +W+  DD  +EH + FP+C FL   
Sbjct: 98  PLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFL--- 154

Query: 254 LETLRFSISNLSMQTHAARMRTFMYW---PSSVPVQPEQLAS 292
           L +      +   +TH+  + ++  W     + PV P   AS
Sbjct: 155 LRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPAS 196



 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 28/68 (41%), Positives = 41/68 (60%)

Query: 46  ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ 105
           E  R++++  +P    V    LA AGF++TG  DKV+CF C   L +WK GD P  +H +
Sbjct: 87  EELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAK 146

Query: 106 LYPSCSFI 113
            +PSC F+
Sbjct: 147 WFPSCQFL 154


>gi|21536421 livin inhibitor of apoptosis isoform alpha [Homo
           sapiens]
          Length = 298

 Score =  112 bits (279), Expect = 1e-24
 Identities = 56/138 (40%), Positives = 75/138 (54%), Gaps = 4/138 (2%)

Query: 266 MQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVE 325
           M +   R+ +F  WP +  V PE LA+AGF++ G  D V+CF C GGL+ W+ GDDPW E
Sbjct: 84  MGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTE 143

Query: 326 HAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTSDTTGEENADPPIIHFGPGESSS 385
           HAKWFP C+FL+R KG++FV  +Q  +     QLL + D   E     P+    P     
Sbjct: 144 HAKWFPSCQFLLRSKGRDFVHSVQETH----SQLLGSWDPWEEPEDAAPVAPSVPASGYP 199

Query: 386 EDAVMMNTPVVKSALEMG 403
           E          +SA E G
Sbjct: 200 ELPTPRREVQSESAQEPG 217



 Score = 96.3 bits (238), Expect = 7e-20
 Identities = 43/61 (70%), Positives = 51/61 (83%), Gaps = 1/61 (1%)

Query: 558 LEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFL 617
           +E QLRRLQEERTCKVC+D+ VS+VF+PCGHL VC ECAP L+ CPICR  ++  VRTFL
Sbjct: 239 VEAQLRRLQEERTCKVCLDRAVSIVFVPCGHL-VCAECAPGLQLCPICRAPVRSRVRTFL 297

Query: 618 S 618
           S
Sbjct: 298 S 298



 Score = 77.4 bits (189), Expect = 4e-14
 Identities = 65/222 (29%), Positives = 94/222 (42%), Gaps = 32/222 (14%)

Query: 76  GVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSASLG-STSKNTSPMRNS 134
           G  D  KC   G    +W  GD P Q+       C   ++L S  LG  T +    +   
Sbjct: 2   GPKDSAKCLHRGPQPSHWAAGDGPTQER------CG-PRSLGSPVLGLDTCRAWDHVDGQ 54

Query: 135 FAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYAMSTEEARFLTYHMW 194
               L P  E      G+ ++LS  P                    M +EE R  +++ W
Sbjct: 55  ILGQLRPLTEEEEE-EGAGATLSRGPAFP----------------GMGSEELRLASFYDW 97

Query: 195 PLTFLSPSEL-ARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRRHFPNCPFLENS 253
           PLT   P EL A AGF++ G  D+V CF C G L +W+  DD  +EH + FP+C FL   
Sbjct: 98  PLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFL--- 154

Query: 254 LETLRFSISNLSMQTHAARMRTFMYW---PSSVPVQPEQLAS 292
           L +      +   +TH+  + ++  W     + PV P   AS
Sbjct: 155 LRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPAS 196



 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 28/68 (41%), Positives = 41/68 (60%)

Query: 46  ELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQ 105
           E  R++++  +P    V    LA AGF++TG  DKV+CF C   L +WK GD P  +H +
Sbjct: 87  EELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAK 146

Query: 106 LYPSCSFI 113
            +PSC F+
Sbjct: 147 WFPSCQFL 154


>gi|119393876 NLR family, apoptosis inhibitory protein isoform 2
           [Homo sapiens]
          Length = 1241

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 30/78 (38%), Positives = 50/78 (64%)

Query: 43  FSCELYRMSTYSTFPAGVPVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQK 102
           F+ E  R+ ++  +P    V   +LA+AG +YTG+ D V+CF CG  L+ W+ GD P+  
Sbjct: 113 FAYEELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDD 172

Query: 103 HKQLYPSCSFIQNLVSAS 120
           H + +P+C F+QN+ S++
Sbjct: 173 HTRCFPNCPFLQNMKSSA 190



 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 43/107 (40%), Positives = 58/107 (54%), Gaps = 3/107 (2%)

Query: 272 RMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFP 331
           R+ +F  WP    V    LA AG +Y G  D V+CF C G L  W+ GDDP  +H + FP
Sbjct: 119 RLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFP 178

Query: 332 RCEFLIRMKGQ-EFVDEIQGRYPHLLEQLLSTSDTTGEEN-ADPPII 376
            C FL  MK   E   ++Q R   L E L +TS++  E++ A  PI+
Sbjct: 179 NCPFLQNMKSSAEVTPDLQSR-GELCELLETTSESNLEDSIAVGPIV 224



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 32/70 (45%), Positives = 44/70 (62%), Gaps = 1/70 (1%)

Query: 184 EEARFLTYHMWPL-TFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEHRR 242
           EE R  ++  WP  + +  + LA+AG +Y G  D V CF+CGG L  W+  DD + +H R
Sbjct: 116 EELRLDSFKDWPRESAVGVAALAKAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTR 175

Query: 243 HFPNCPFLEN 252
            FPNCPFL+N
Sbjct: 176 CFPNCPFLQN 185


>gi|38788243 myosin regulatory light chain interacting protein [Homo
           sapiens]
          Length = 445

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 25/60 (41%), Positives = 39/60 (65%)

Query: 558 LEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFL 617
           L+E+LR+L+E   C VC ++E++  F PCGH V C+ CA  L+ CP+CR  ++     +L
Sbjct: 374 LQEKLRKLKEAMLCMVCCEEEINSTFCPCGHTVCCESCAAQLQSCPVCRSRVEHVQHVYL 433


>gi|153792694 baculoviral IAP repeat-containing 6 [Homo sapiens]
          Length = 4857

 Score = 62.8 bits (151), Expect = 9e-10
 Identities = 32/77 (41%), Positives = 41/77 (53%), Gaps = 6/77 (7%)

Query: 181 MSTEEARFLTYHMWP---LTFLSPSELARAGFYY---IGPGDRVACFACGGKLSNWEPKD 234
           M +E  R  T+  WP     +  P  +A+AGFY+       DR  CF C   L  WEP D
Sbjct: 283 MYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTD 342

Query: 235 DAMSEHRRHFPNCPFLE 251
           +  SEH RH PNCPF++
Sbjct: 343 EPWSEHERHSPNCPFVK 359



 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 5/82 (6%)

Query: 260 SISNLSMQTHAARMRTFMYWPSSVP--VQPEQLASAGFYYV---GRNDDVKCFCCDGGLR 314
           S+    M + A R  TF  WP       QP+ +A AGFY+      +D   CF C   L 
Sbjct: 277 SVDRSLMYSEANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLV 336

Query: 315 CWESGDDPWVEHAKWFPRCEFL 336
           CWE  D+PW EH +  P C F+
Sbjct: 337 CWEPTDEPWSEHERHSPNCPFV 358



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 22/74 (29%), Positives = 42/74 (56%), Gaps = 5/74 (6%)

Query: 46  ELYRMSTYSTFP-AGVPVSERS-LARAGFYY---TGVNDKVKCFCCGLMLDNWKLGDSPI 100
           E  R  T++++P  G   ++   +A+AGFY+   +  +D+  CF C + L  W+  D P 
Sbjct: 286 EANRRETFTSWPHVGYRWAQPDPMAQAGFYHQPASSGDDRAMCFTCSVCLVCWEPTDEPW 345

Query: 101 QKHKQLYPSCSFIQ 114
            +H++  P+C F++
Sbjct: 346 SEHERHSPNCPFVK 359


>gi|62865649 rififylin [Homo sapiens]
          Length = 363

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 14/102 (13%)

Query: 524 FKNC-----LKEIDSTLYKNLFVDKNMKYIPT--EDVSGLSLEEQLRRLQEERTCKVCMD 576
           +K C     L E  + LYK+    K ++++ +  ED +G ++   L    EE  CK+CMD
Sbjct: 269 YKGCCEKWELMERVTRLYKD---QKGLQHLVSGAEDQNGGAVPSGL----EENLCKICMD 321

Query: 577 KEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
             +  V + CGH+V C +C   + +CPICR  +   V  F S
Sbjct: 322 SPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS 363


>gi|17432433 rififylin [Homo sapiens]
          Length = 363

 Score = 60.5 bits (145), Expect = 5e-09
 Identities = 34/102 (33%), Positives = 53/102 (51%), Gaps = 14/102 (13%)

Query: 524 FKNC-----LKEIDSTLYKNLFVDKNMKYIPT--EDVSGLSLEEQLRRLQEERTCKVCMD 576
           +K C     L E  + LYK+    K ++++ +  ED +G ++   L    EE  CK+CMD
Sbjct: 269 YKGCCEKWELMERVTRLYKD---QKGLQHLVSGAEDQNGGAVPSGL----EENLCKICMD 321

Query: 577 KEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
             +  V + CGH+V C +C   + +CPICR  +   V  F S
Sbjct: 322 SPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHVFRS 363


>gi|37595539 ring finger protein 34 isoform 1 [Homo sapiens]
          Length = 373

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 21/58 (36%), Positives = 34/58 (58%)

Query: 561 QLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
           QL+  +++  C++CMD  +  V + CGH+V C +C   + +CPICR  +   V  F S
Sbjct: 316 QLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS 373


>gi|37595537 ring finger protein 34 isoform 2 [Homo sapiens]
          Length = 372

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 21/58 (36%), Positives = 34/58 (58%)

Query: 561 QLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
           QL+  +++  C++CMD  +  V + CGH+V C +C   + +CPICR  +   V  F S
Sbjct: 315 QLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS 372


>gi|30348954 mindbomb homolog 1 [Homo sapiens]
          Length = 1006

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 22/58 (37%), Positives = 36/58 (62%)

Query: 556 LSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTV 613
           L  +EQ++   +   C VC DK+ +V+F PCGH+  C+ CA  ++KC  CR +++  V
Sbjct: 851 LICKEQVQSRTKIEECVVCSDKKAAVLFQPCGHMCACENCANLMKKCVQCRAVVERRV 908



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 21/53 (39%), Positives = 36/53 (67%), Gaps = 2/53 (3%)

Query: 558  LEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIK 610
            L++QL+ ++E+  C VC+D+  +++F+ CGH   CQ C   + +CPICR  I+
Sbjct: 950  LQQQLQDIKEQTMCPVCLDRLKNMIFL-CGH-GTCQLCGDRMSECPICRKAIE 1000



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 16/36 (44%), Positives = 23/36 (63%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICR 606
           C VC D +   +F PCGH+  C  C+P ++KC IC+
Sbjct: 819 CMVCSDMKRDTLFGPCGHIATCSLCSPRVKKCLICK 854


>gi|53729363 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 20/48 (41%), Positives = 31/48 (64%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
           C VC+++E  ++F+ CGH+  CQ+C   LR CP+CR  I   +R + S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722


>gi|53729361 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 20/48 (41%), Positives = 31/48 (64%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
           C VC+++E  ++F+ CGH+  CQ+C   LR CP+CR  I   +R + S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722


>gi|53729359 leucine rich repeat and sterile alpha motif containing
           1 [Homo sapiens]
          Length = 723

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 20/48 (41%), Positives = 31/48 (64%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFLS 618
           C VC+++E  ++F+ CGH+  CQ+C   LR CP+CR  I   +R + S
Sbjct: 675 CVVCLEREAQMIFLNCGHVCCCQQCCQPLRTCPLCRQDIAQRLRIYHS 722


>gi|59859878 baculoviral IAP repeat-containing protein 5 isoform 1
           [Homo sapiens]
          Length = 142

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 6/83 (7%)

Query: 174 TNPYSYAMSTEEARFLTYHMWPLT---FLSPSELARAGFYYI---GPGDRVACFACGGKL 227
           T P ++    ++ R  T+  WP       +P  +A AGF +       D   CF C  +L
Sbjct: 5   TLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKEL 64

Query: 228 SNWEPKDDAMSEHRRHFPNCPFL 250
             WEP DD + EH++H   C FL
Sbjct: 65  EGWEPDDDPIEEHKKHSSGCAFL 87



 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 5/70 (7%)

Query: 272 RMRTFMYWP--SSVPVQPEQLASAGFYYVGRNDD---VKCFCCDGGLRCWESGDDPWVEH 326
           R+ TF  WP        PE++A AGF +    ++    +CF C   L  WE  DDP  EH
Sbjct: 18  RISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEEH 77

Query: 327 AKWFPRCEFL 336
            K    C FL
Sbjct: 78  KKHSSGCAFL 87



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 22/71 (30%), Positives = 37/71 (52%), Gaps = 5/71 (7%)

Query: 48  YRMSTYSTFP--AGVPVSERSLARAGFYYTGVN---DKVKCFCCGLMLDNWKLGDSPIQK 102
           +R+ST+  +P   G   +   +A AGF +       D  +CF C   L+ W+  D PI++
Sbjct: 17  HRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFCFKELEGWEPDDDPIEE 76

Query: 103 HKQLYPSCSFI 113
           HK+    C+F+
Sbjct: 77  HKKHSSGCAFL 87


>gi|21264330 mindbomb homolog 2 [Homo sapiens]
          Length = 1013

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 22/60 (36%), Positives = 36/60 (60%), Gaps = 2/60 (3%)

Query: 558  LEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVRTFL 617
            L+ + R+++E  TC +C+D  + +VF  CGH   C  C  +L  CPICR  I+  ++ F+
Sbjct: 956  LQSRYRQMEERITCPICIDSHIRLVF-QCGH-GACAPCGSALSACPICRQPIRDRIQIFV 1013



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 18/48 (37%), Positives = 28/48 (58%)

Query: 567 EERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLRKCPICRGIIKGTVR 614
           E   C VC +  + V+F PC H  VC+ECA  ++KC  C+ ++   +R
Sbjct: 886 EAAECLVCSELALLVLFSPCQHRTVCEECARRMKKCIRCQVVVSKKLR 933


>gi|14042925 ring finger protein 26 [Homo sapiens]
          Length = 433

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 22/63 (34%), Positives = 34/63 (53%), Gaps = 7/63 (11%)

Query: 562 LRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSL-------RKCPICRGIIKGTVR 614
           L+  +E + C +C D+  +V+ +PC HL +CQ C   L       R CP+CR  I  T+ 
Sbjct: 371 LKEQEERKKCVICQDQSKTVLLLPCRHLCLCQACTEILMRHPVYHRNCPLCRRGILQTLN 430

Query: 615 TFL 617
            +L
Sbjct: 431 VYL 433


>gi|47716512 mex-3 homolog B [Homo sapiens]
          Length = 569

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 25/68 (36%), Positives = 33/68 (48%), Gaps = 6/68 (8%)

Query: 554 SGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECA-----PSLRKCPICRGI 608
           S  S    LRR +  R C VC + EV    +PCGH + C ECA      S  +CP+C   
Sbjct: 502 SSSSSSSGLRR-KGSRDCSVCFESEVIAALVPCGHNLFCMECANRICEKSEPECPVCHTA 560

Query: 609 IKGTVRTF 616
           +   +R F
Sbjct: 561 VTQAIRIF 568


>gi|45387949 ring finger and SPRY domain containing 1 [Homo sapiens]
          Length = 576

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 27/83 (32%), Positives = 39/83 (46%), Gaps = 12/83 (14%)

Query: 544 NMKYIPTEDVSGLSLEEQL-----RRLQ-------EERTCKVCMDKEVSVVFIPCGHLVV 591
           +MK+    D + L+ EE++     RRL         E  C +C D+       PCGH  +
Sbjct: 488 SMKFSTFNDYAFLTAEEKIILPRHRRLALLKQVSIRENCCSLCCDEVADTQLKPCGHSDL 547

Query: 592 CQECAPSLRKCPICRGIIKGTVR 614
           C +CA  L  CP+CR  I   +R
Sbjct: 548 CMDCALQLETCPLCRKEIVSRIR 570


>gi|217416388 neuralized homolog 1B [Homo sapiens]
          Length = 555

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 20/51 (39%), Positives = 27/51 (52%), Gaps = 5/51 (9%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRK-----CPICRGIIKGTVRTF 616
           C VC D EV  V   CGH+ +C  C   L++     CPICR  IK  ++ +
Sbjct: 503 CTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIY 553


>gi|5729765 cell growth regulator with ring finger domain 1 [Homo
           sapiens]
          Length = 332

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 24/88 (27%), Positives = 39/88 (44%), Gaps = 14/88 (15%)

Query: 537 KNLFVDKNMKYIPTEDVS--------------GLSLEEQLRRLQEERTCKVCMDKEVSVV 582
           K LF+  N  + P+ + S              GLS  E     +  + C VC +  V+ V
Sbjct: 226 KQLFMSANNNFTPSNNSSSEEKNTDRSLLEKVGLSESEVEPSEENSKDCVVCQNGTVNWV 285

Query: 583 FIPCGHLVVCQECAPSLRKCPICRGIIK 610
            +PC H  +C  C    ++CP+CR  ++
Sbjct: 286 LLPCRHTCLCDGCVKYFQQCPMCRQFVQ 313


>gi|223278368 neuralized-like [Homo sapiens]
          Length = 574

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 5/53 (9%)

Query: 571 CKVCMDKEVSVVFIPCGHLVVCQECAPSLRK-----CPICRGIIKGTVRTFLS 618
           C +C +  V  V   CGH+ +C  C   L+K     CPICR  IK  ++T+ S
Sbjct: 521 CTICYEHAVDTVIYTCGHMCLCYACGLRLKKALHACCPICRRPIKDIIKTYRS 573


>gi|171542821 mitochondrial ubiquitin ligase activator of NFKB 1
           [Homo sapiens]
          Length = 352

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 48/215 (22%), Positives = 88/215 (40%), Gaps = 14/215 (6%)

Query: 407 DLVKQTVQSKILTTGENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRM 466
           DL  +TV  K   + +++    D++   ++ E  K  +E     EEM     +L     +
Sbjct: 149 DLGLETVYEKFHPSIQSF---TDVIGHYISGERPKGIQE----TEEMLKVGATLTGVGEL 201

Query: 467 ALFQQLTCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKN 526
            L      + P    +     ++ Q+ D + Q+ +  ++  +++   LV G A       
Sbjct: 202 VLDNNSVRLQPPKQGM--QYYLSSQDFDSLLQRQESSVRLWKVL--ALVFGFATCATLFF 257

Query: 527 CLKEIDSTLYKNLFVDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPC 586
            L++      + L + +  +     +   LS  +   R   +  C VC+    S VF+ C
Sbjct: 258 ILRKQYLQRQERLRLKQMQEEFQEHEAQLLSRAKPEDRESLKSACVVCLSSFKSCVFLEC 317

Query: 587 GHLVVCQEC---APSLRKCPICRGIIKGTVRTFLS 618
           GH+  C EC    P  +KCPICR  I   +  + S
Sbjct: 318 GHVCSCTECYRALPEPKKCPICRQAITRVIPLYNS 352


>gi|147902746 MEX3A protein [Homo sapiens]
          Length = 520

 Score = 46.2 bits (108), Expect = 9e-05
 Identities = 19/53 (35%), Positives = 27/53 (50%), Gaps = 5/53 (9%)

Query: 569 RTCKVCMDKEVSVVFIPCGHLVVCQECAPSL-----RKCPICRGIIKGTVRTF 616
           R C VC + EV+   +PCGH + C ECA  +      +CP+C       +R F
Sbjct: 467 RDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIF 519


>gi|40788015 caspase recruitment domain protein 12 [Homo sapiens]
          Length = 1024

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/84 (34%), Positives = 49/84 (58%), Gaps = 2/84 (2%)

Query: 458 LSLIRKNRMALFQQL--TCVLPILDNLLKANVINKQEHDIIKQKTQIPLQARELIDTILV 515
           ++ I+ N  AL Q++  T +  I D+L   NV+N++E +II  +      AR +I  IL 
Sbjct: 1   MNFIKDNSRALIQRMGMTVIKQITDDLFVWNVLNREEVNIICCEKVEQDAARGIIHMILK 60

Query: 516 KGNAAANIFKNCLKEIDSTLYKNL 539
           KG+ + N+F   LKE +  L+++L
Sbjct: 61  KGSESCNLFLKSLKEWNYPLFQDL 84


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,169,678
Number of Sequences: 37866
Number of extensions: 1109849
Number of successful extensions: 5721
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 5457
Number of HSP's gapped (non-prelim): 341
length of query: 618
length of database: 18,247,518
effective HSP length: 108
effective length of query: 510
effective length of database: 14,157,990
effective search space: 7220574900
effective search space used: 7220574900
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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