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Search of human proteins with 44680154
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44680154 myotubularin-related protein 2 isoform 1 [Homo
sapiens]
(643 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 1302 0.0
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 1169 0.0
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 1169 0.0
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 925 0.0
gi|4557896 myotubularin [Homo sapiens] 800 0.0
gi|21361759 myotubularin related protein 8 [Homo sapiens] 377 e-104
gi|134142348 myotubularin related protein 6 [Homo sapiens] 371 e-102
gi|225543474 myotubularin related protein 7 [Homo sapiens] 357 2e-98
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 350 2e-96
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 350 2e-96
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 350 2e-96
gi|19923424 myotubularin related protein 9 [Homo sapiens] 333 2e-91
gi|217272865 myotubularin related protein 4 [Homo sapiens] 329 4e-90
gi|29788755 SET binding factor 2 [Homo sapiens] 174 2e-43
gi|124028527 myotubularin related protein 10 [Homo sapiens] 165 1e-40
gi|239735519 SET binding factor 1 [Homo sapiens] 147 4e-35
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 144 2e-34
gi|94721263 myotubularin related protein 12 [Homo sapiens] 144 3e-34
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 141 2e-33
gi|117938274 jumpy isoform 3 [Homo sapiens] 40 0.009
gi|117938272 jumpy isoform 1 [Homo sapiens] 40 0.009
gi|117938270 jumpy isoform 2 [Homo sapiens] 40 0.009
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 33 0.81
gi|22027646 angiomotin like 1 [Homo sapiens] 33 1.1
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 32 1.8
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 32 1.8
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 32 1.8
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s... 32 1.8
gi|71774083 myc proto-oncogene protein [Homo sapiens] 32 2.4
gi|21735415 centromere protein B [Homo sapiens] 32 2.4
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 1302 bits (3370), Expect = 0.0
Identities = 643/643 (100%), Positives = 643/643 (100%)
Query: 1 MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPD 60
MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPD
Sbjct: 1 MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPD 60
Query: 61 LRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERD 120
LRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERD
Sbjct: 61 LRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERD 120
Query: 121 PPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLM 180
PPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLM
Sbjct: 121 PPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLM 180
Query: 181 KYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTY 240
KYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTY
Sbjct: 181 KYAFPVSNNLPLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTY 240
Query: 241 PALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDE 300
PALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDE
Sbjct: 241 PALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDE 300
Query: 301 KYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMR 360
KYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMR
Sbjct: 301 KYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMR 360
Query: 361 ESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDG 420
ESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDG
Sbjct: 361 ESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDG 420
Query: 421 WDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVF 480
WDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVF
Sbjct: 421 WDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVF 480
Query: 481 LQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSL 540
LQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSL
Sbjct: 481 LQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSL 540
Query: 541 WSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKEL 600
WSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKEL
Sbjct: 541 WSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKEL 600
Query: 601 LAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV 643
LAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 601 LAKRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQTVV 643
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 1169 bits (3023), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 73 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 132
MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 133 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 192
NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 193 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 252
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 253 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 312
EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 313 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 372
SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 373 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 432
NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 433 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 492
LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 493 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 552
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 553 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 612
NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 613 ELQREISNRSTSSSERASSPAQCVTPVQTVV 643
ELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 1169 bits (3023), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 73 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 132
MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 133 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 192
NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 193 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 252
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 253 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 312
EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 313 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 372
SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 373 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 432
NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 433 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 492
LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 493 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 552
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 553 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 612
NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 613 ELQREISNRSTSSSERASSPAQCVTPVQTVV 643
ELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 925 bits (2391), Expect = 0.0
Identities = 442/634 (69%), Positives = 530/634 (83%), Gaps = 2/634 (0%)
Query: 11 GSQPAAARPPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKL 70
G A +R PSV++L S + SH E +A++ S S S +++N S D + LR+ NKL
Sbjct: 33 GGATAGSRQPSVETLDSPTGSHVEWCKQLIAATISSQISGSVTSENVSRDYKALRDGNKL 92
Query: 71 AEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLG 130
A+MEE PL PGE+IK + KDV YICPF GAV GTLTVT+++LYFK++ERDP F+LD LG
Sbjct: 93 AQMEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLG 152
Query: 131 VINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNL 190
VI+RVEKIG A S G+NS G+E VCKD+RNLR A+K E +++ IFENL K+AFP+SN
Sbjct: 153 VISRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQ 211
Query: 191 PLFAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANI 250
LFAF YKE FP NGWK+YDP+ EY+RQG+PNESW+I+KIN YE CDTYPA++VVP ++
Sbjct: 212 ALFAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSV 271
Query: 251 PDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSN 310
D++L +VA+FR++GR+PVLSWIHPESQATITRCSQP+VG + KR KEDEKYLQ IMD+N
Sbjct: 272 KDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDAN 331
Query: 311 AQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV 370
AQSHK+ IFDAR + A NK KGGGYESE AY NAELVFL+IHNIHVMRESLRKLKEIV
Sbjct: 332 AQSHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIV 391
Query: 371 YPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSL 430
YP+I+E WLSN++ THWLE+I+++LAGA+RIADK+ESGKTSVVVHCSDGWDRTAQLTSL
Sbjct: 392 YPSIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSL 451
Query: 431 AMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQM 490
AMLMLD YYRTI+GFE LVEKEW+SFGHRF LRVGHG+ NHADADRSP+FLQF+DCVWQM
Sbjct: 452 AMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQM 511
Query: 491 TRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLED 550
TRQFP+AFEFNE FLITILDHLYSCLFGTFLCN EQQR KE++ +T+SLWSYINSQL++
Sbjct: 512 TRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDE 571
Query: 551 FTNPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKK 610
F+NP + +Y NHVLYPVAS+ HLELWV YY+RWNPRM+PQ PIH KELLA RAELQK+
Sbjct: 572 FSNPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKR 631
Query: 611 VEELQREISNRS-TSSSERASSPAQCVTPVQTVV 643
VE LQRE++ R+ +SSSER SSP+ T V T V
Sbjct: 632 VEGLQREVATRAVSSSSERGSSPSHSATSVHTSV 665
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 800 bits (2067), Expect = 0.0
Identities = 393/620 (63%), Positives = 480/620 (77%), Gaps = 22/620 (3%)
Query: 25 LSSASTS-HSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKLAEMEEPPLLPGEN 83
++SASTS ++ +S+ +S TS D + DL E P LPGE
Sbjct: 1 MASASTSKYNSHSLENESIK-------RTSRDGVNRDLT-----------EAVPRLPGET 42
Query: 84 IKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASS 143
+ K+V YICPF G ++G + +TNYRLY +S+E D +LD LGVI+R+EK+GGA+S
Sbjct: 43 LIT-DKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVISRIEKMGGATS 101
Query: 144 RGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPE 203
RGENSYGL+ CKD+RNLRFA K EG +RR +FE L +YAFP++++LPLFAF +E F
Sbjct: 102 RGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLFAFLNEEKFNV 161
Query: 204 NGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRS 263
+GW +Y+P+ EYRRQG+PN WRIT IN+ YELCDTYPALLVVP D++L+RVA+FRS
Sbjct: 162 DGWTVYNPVEEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRVATFRS 221
Query: 264 RGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARP 323
R RIPVLSWIHPE++ I RCSQP+VG+SGKR+K+DEKYL I ++N Q K+ I+DARP
Sbjct: 222 RNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTIYDARP 281
Query: 324 SVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNL 383
SVNAVANKA GGGYES+DAY NAEL FLDIHNIHVMRESL+K+K+IVYPN+EE+HWLS+L
Sbjct: 282 SVNAVANKATGGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPNVEESHWLSSL 341
Query: 384 ESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIR 443
ESTHWLEHIKL+L GA+++ADKV SGK+SV+VHCSDGWDRTAQLTSLAMLMLD +YR+I
Sbjct: 342 ESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAMLMLDSFYRSIE 401
Query: 444 GFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEY 503
GFE+LV+KEW+SFGH+F R+GHGDKNH DADRSP+FLQFIDCVWQM++QFPTAFEFNE
Sbjct: 402 GFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQFPTAFEFNEQ 461
Query: 504 FLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHV 563
FLI ILDHLYSC FGTFL N E R ++ + +RTVSLWS INS E F NP Y N V
Sbjct: 462 FLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLINSNKEKFKNPFYTKEINRV 521
Query: 564 LYPVASMRHLELWVGYYIRWNPRMKPQE--PIHNRYKELLAKRAELQKKVEELQREISNR 621
LYPVASMRHLELWV YYIRWNPR+K Q+ P+ RY ELLA R E K++EELQ S +
Sbjct: 522 LYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKRLEELQLANSAK 581
Query: 622 STSSSERASSPAQCVTPVQT 641
+ SSP+Q + VQT
Sbjct: 582 LSDPPTSPSSPSQMMPHVQT 601
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 377 bits (969), Expect = e-104
Identities = 200/481 (41%), Positives = 294/481 (61%), Gaps = 20/481 (4%)
Query: 159 RNLRFAH--KPEGRTRRSIFENLMKYAFPVSNNLP--LFAFEYK----EVFPENGWKLYD 210
+N R AH ++ +L+K + P LP L+AF Y + E+GWKL D
Sbjct: 75 KNFRVAHFVLDSDLVCHEVYISLLKLSQPA---LPEDLYAFSYNPKSSKEMRESGWKLID 131
Query: 211 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 270
P+ ++ R GIPN +W IT N YE+C TYP +VVP ++ + + FRS+ R+PVL
Sbjct: 132 PISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVL 191
Query: 271 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 330
S+++ E+ A I RCSQP+ G R +DE L+AI +N S +++ D RP +NA+AN
Sbjct: 192 SYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMAN 250
Query: 331 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTH 387
+A G GYE+ED Y N F+ I NIHVMR SL+KL E+ P + E +LS LES+
Sbjct: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE--FLSGLESSG 308
Query: 388 WLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEV 447
WL HIK I+ + I V+ K SV+VHCSDGWDRTAQ+ S+A ++LD +YRT +G +
Sbjct: 309 WLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMI 368
Query: 448 LVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 507
L+EKEW+S GH+F R GH D + + SP+F QF+DC+WQ+ QFP AFEFNE FL+
Sbjct: 369 LIEKEWISMGHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLE 426
Query: 508 ILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH-VLYP 566
I DH++SC FG FL N ++ R + ++T S+W ++ + DF NPLY ++ + VL P
Sbjct: 427 IHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNP 486
Query: 567 VASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSS 626
+++ W G Y R++ ++P++ + E+ +RA L+ V EL++++ R
Sbjct: 487 STVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPE 546
Query: 627 E 627
E
Sbjct: 547 E 547
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 371 bits (952), Expect = e-102
Identities = 203/535 (37%), Positives = 308/535 (57%), Gaps = 19/535 (3%)
Query: 100 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 159
++ GTL +T L F + ++L + VEK+ +S L CK+ R
Sbjct: 24 SLTGTLYLTATHLLFIDSHQKETWILHHHIA---SVEKLALTTS----GCPLVIQCKNFR 76
Query: 160 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----GWKLYDPLLEY 215
+ F P R I+ +L++ + L+AF Y ++ GW+L D EY
Sbjct: 77 TVHFI-VPRERDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAEEY 134
Query: 216 RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHP 275
+R G+PN W+++ N Y++C+TYP L VP + + FRS+GR PVLS+ H
Sbjct: 135 KRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQ 194
Query: 276 ESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGG 335
+ +A I RCSQP+ G S R EDE LQAI +N + +++ D RP +NA+AN+A G
Sbjct: 195 DKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGK 253
Query: 336 GYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV-YPNIEETHWLSNLESTHWLEHIKL 394
GYE+ED Y N F+ I NIHVMR SL+KL E+ + + S LES+ WL HIK
Sbjct: 254 GYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKA 313
Query: 395 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 454
++ A+ +A + SV+VHCSDGWDRT+Q+ SL L+LD YYRTI+GF VL+EK+W+
Sbjct: 314 VMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWI 373
Query: 455 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYS 514
SFGH+F R G D + + SPVF QF++CVW +T QFP AFEF+E FL+ I +H++S
Sbjct: 374 SFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHS 431
Query: 515 CLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH--VLYPVASMRH 572
C FG FL N +++R + L ++T SLW ++ + + NPLY S S+ VL P +
Sbjct: 432 CQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFN 491
Query: 573 LELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSE 627
+ W Y +++ + P++ + N + + +L+K +++L+ +I R ++
Sbjct: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTD 546
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 357 bits (916), Expect = 2e-98
Identities = 207/531 (38%), Positives = 307/531 (57%), Gaps = 32/531 (6%)
Query: 100 AVRGTLTVTNYRLYFKSMERDP---PFVLDASLGVINRVEKIGGASSRGENSYGLETVCK 156
A GTL +T + F DP ++L + + I + + L CK
Sbjct: 23 AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK-------QATTATGCPLLIRCK 75
Query: 157 DIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP----ENGWKLYDPL 212
+ + ++ P+ R ++ +L++ A PV L+ F + + E GW L D
Sbjct: 76 NFQIIQLII-PQERDCHDVYISLIRLARPVKYE-ELYCFSFNPMLDKEEREQGWVLIDLS 133
Query: 213 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSW 272
EY R G+PN W+++ +N Y +CD+YP L VP + + + FRSR R PVLS+
Sbjct: 134 EEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSY 193
Query: 273 IHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 332
+ ++ A+I R SQP+ G S R EDE+ LQAI +N S +++ D RP +NA+AN+A
Sbjct: 194 YYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRA 252
Query: 333 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTHWL 389
G GYE+ED Y N + F+ I NIHVMR SL+K+ E+ P++ + W LE++ WL
Sbjct: 253 AGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWL 310
Query: 390 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV 449
HIK I+ + IA V SV+VHCSDGWDRTAQ+ S+A L+LD +YRT++GF VL+
Sbjct: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
Query: 450 EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITIL 509
EK+W+SFGH+F R G+ D + + SPV QFI+CVWQ+ QFP AFEFNE FLI I
Sbjct: 371 EKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
Query: 510 DHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLY---GSYSNHVLY- 565
H+YSC FG FLCNS+++R + + +RT SLW+++ D+ NPL+ S + L+
Sbjct: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
Query: 566 PVASMRHL-ELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ 615
P + + W G Y R+ M+P++ + + L+A + E Q+ EEL+
Sbjct: 489 PTTPCNFMYKFWSGMYNRFEKGMQPRQSVTD---YLMAVKEETQQLEEELE 536
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 105 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 164
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 165 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 210
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 211 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 261
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 262 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 308
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 309 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 336
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 337 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 396
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 397 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 456
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 457 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 516
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 517 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 576
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 577 VGYYIRWNPRMKPQEPI 593
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 105 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 164
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 165 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 210
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 211 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 261
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 262 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 308
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 309 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 336
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 337 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 396
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 397 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 456
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 457 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 516
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 517 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 576
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 577 VGYYIRWNPRMKPQEPI 593
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 105 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 164
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 165 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 210
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 211 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 261
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 262 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 308
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 309 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 336
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 337 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 396
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 397 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 456
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 457 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 516
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 517 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 576
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 577 VGYYIRWNPRMKPQEPI 593
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 333 bits (855), Expect = 2e-91
Identities = 199/547 (36%), Positives = 305/547 (55%), Gaps = 30/547 (5%)
Query: 96 PFTGAVRGTLTVTNYRLYFKSMERDPP--FVLDASLGVINRVEKIGGASSRGENSYGLET 153
PF AV GTL +T + L S + + ++L +++ I++ R S G
Sbjct: 20 PFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDK---------RFVGSLGTII 70
Query: 154 V-CKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP--ENGWKLYD 210
+ CKD R ++ P +I ++ + S L ++ F Y+ +F E+GW +
Sbjct: 71 IKCKDFRIIQL-DIPGMEECLNIASSIEALSTLDSITL-MYPFFYRPMFEVIEDGWHSFL 128
Query: 211 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 270
P E+ WR++ +N+ + +C +YP ++ VP +I DE L++VA+FR GR PVL
Sbjct: 129 PEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVL 188
Query: 271 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 330
S+ H ++ I R QP+ G +G+R KEDEK + A + + + +I D R A
Sbjct: 189 SYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRG---YIIDTRSLNVAQQT 245
Query: 331 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETH----WLSNLEST 386
+AKGGG+E E Y + I H+++ESL KL E ++TH WLS LE++
Sbjct: 246 RAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACN---DQTHNMDRWLSKLEAS 302
Query: 387 HWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFE 446
+WL HIK IL A A ++ S+++H ++G D T Q+TSLA ++L+ RTIRGFE
Sbjct: 303 NWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFE 362
Query: 447 VLVEKEWLSFGHRFQLRVGHGDK-NHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFL 505
L+E+EWL GH FQ R N +PVFL F+DCVWQ+ RQFP +FEFNE FL
Sbjct: 363 ALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFL 422
Query: 506 ITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN--SQLEDFTNPLYGSYSNHV 563
I + +H Y+ FGTFL N+E +R K L ++T+SLWS++N S+L FTNPL+ + +N V
Sbjct: 423 IMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEA-NNLV 481
Query: 564 LYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRST 623
++P + + L LW G ++RWN K + + ++ ELQ KV L+R+++ T
Sbjct: 482 IWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELET 541
Query: 624 SSSERAS 630
+ S
Sbjct: 542 EDGMQES 548
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 329 bits (844), Expect = 4e-90
Identities = 205/583 (35%), Positives = 303/583 (51%), Gaps = 83/583 (14%)
Query: 55 DNFSPDLRVLRESNKLAEMEEP-PLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLY 113
D F P V E N ++ P +L GE ++ + + A + ++NYRL+
Sbjct: 16 DLFPPKELVKEEEN----LQVPFTVLQGEGVEFLGR----------AADALIAISNYRLH 61
Query: 114 FKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRR 173
K + V++ L +I+ VE + + L CKD + +R H + +
Sbjct: 62 IKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSKVVR-CHFSTFKQCQ 108
Query: 174 SIFENLMKYAFPVSNNLPLFAFEYKE-----VFPENGWKLYDP--------LLEYRRQGI 220
L + + LFAF Y + L P E R G
Sbjct: 109 EWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEHIRCRQEAELARMGF 168
Query: 221 PNES-WRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQA 279
++ WR++ IN Y+LC +YP L+VP I D+EL+ VASFRS RIPV+ + H + A
Sbjct: 169 DLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWKRIPVVVYRHLRNGA 228
Query: 280 TITRCSQPMVGVSGKRSKEDEKYLQAI--------------------------------- 306
I RCSQP + G R+ +DE + +I
Sbjct: 229 AIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLSTGNNDTSEACDADFD 288
Query: 307 --------MDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHV 358
++S A K+ I DAR AVAN+AKGGG E E+ Y N E+VF+ + NIH
Sbjct: 289 SSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYPNCEVVFMGMANIHA 348
Query: 359 MRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCS 418
+R S + L+ + + ++WLS LEST WL+H+ ++L A+ +A+ V+ V+VHCS
Sbjct: 349 IRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVANTVDREGRPVLVHCS 408
Query: 419 DGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSP 478
DGWDRT Q+ +LA ++LD YYRT+ GF+VLVE +WL FGH+F R GH + ++ P
Sbjct: 409 DGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQENVEDQNEQCP 468
Query: 479 VFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTV 538
VFLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL N+ +R K N+ KRT
Sbjct: 469 VFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCEREKRNIYKRTC 528
Query: 539 SLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581
S+W+ + + ++F N LY S+ VL+PV +R L LW Y+
Sbjct: 529 SVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 174 bits (442), Expect = 2e-43
Identities = 136/452 (30%), Positives = 198/452 (43%), Gaps = 96/452 (21%)
Query: 223 ESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATIT 282
E +RIT N Y LC +YP LLVVP + D L RVA R+PV+ W + S +
Sbjct: 1136 EYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLL 1195
Query: 283 RC-------------------SQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIF------ 317
R + P + S E EKYLQA++++ + K+
Sbjct: 1196 RSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLT 1255
Query: 318 ---IFDARPSVNA---------------------VANKAKGGGYESEDAYQN-------- 345
F P V A +A K + + QN
Sbjct: 1256 VRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAA 1315
Query: 346 --------------------AELVFLDIHNIHVMRESLRKLKEIVYPNI----EETHWLS 381
E V ++ H I ++ S +KL P+ E +L
Sbjct: 1316 LYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLK 1375
Query: 382 NLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRT 441
L + W + I+ A+ +++ +E+G +SV+V +GWD TAQ+TSL L+ D +YRT
Sbjct: 1376 ALGDSEWFPQLHRIMQLAVVVSEVLENG-SSVLVCLEEGWDITAQVTSLVQLLSDPFYRT 1434
Query: 442 IRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFN 501
+ GF++LVEKEWLSFGH+F R N + +PVFLQF+DCV Q+ Q+PT FEFN
Sbjct: 1435 LEGFQMLVEKEWLSFGHKFSQR-SSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFN 1493
Query: 502 EYFLITILDHLYSCLFGTFLCNSEQQRGK---------ENLPKRTVSLWSYI---NSQLE 549
Y+L + H S F TFL +S+ +R + E K+ V +W I + +
Sbjct: 1494 LYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSP 1553
Query: 550 DFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 581
F N LY L P ++ L+ W YYI
Sbjct: 1554 IFFNYLYSPLEIEALKPNVNVSSLKKW-DYYI 1584
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 165 bits (418), Expect = 1e-40
Identities = 144/521 (27%), Positives = 228/521 (43%), Gaps = 103/521 (19%)
Query: 75 EPPLLPGENIKDMAKDVTYI--CPFTGAVR----GTLTVTNYRLYFKSM----------- 117
EP LLPGE + +V ++ C T + G L +N+++ F +
Sbjct: 35 EPVLLPGEIV---VNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYR 91
Query: 118 -----ERDPPFVLDASLGVIN---RVEKIGGASSRGE-NSYGLETVCKDIRNLRFAHKPE 168
E D P + +N R +K+ G + + + N L CKD R +RF
Sbjct: 92 NLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDES 151
Query: 169 G-RTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----------------------- 204
G + + + + Y+ P L LFAFEY N
Sbjct: 152 GPESAKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGA 210
Query: 205 --GWKLYDPLLE--------YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEE 254
G PL E +R G WR+ INE Y + P +VVP+++ D++
Sbjct: 211 GGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVPSSLADQD 268
Query: 255 LKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSH 314
LK + R+P+ W H A + ++ ++ K D++ AI S+ Q
Sbjct: 269 LKIFSHSFVGRRMPLWCWSHSNGSALV---RMALIKDVLQQRKIDQRICNAITKSHPQRS 325
Query: 315 KIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEI-VYPN 373
++ D + + NI ++ + KLK++ V
Sbjct: 326 DVYKSDLDKT----------------------------LPNIQEVQAAFVKLKQLCVNEP 357
Query: 374 IEETH--WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 431
EET WLS+LE+T WLE+++ L + + +ES SVV+ +G D + + SL
Sbjct: 358 FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLV 417
Query: 432 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 491
+MLD Y+RTI GF+ L++KEW+ G++F R H ++ + SP+FL F+D WQ+
Sbjct: 418 QVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLL 474
Query: 492 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKEN 532
Q+P AFEF+E +L + D LFGTFL NS QR K++
Sbjct: 475 EQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 147 bits (370), Expect = 4e-35
Identities = 94/281 (33%), Positives = 151/281 (53%), Gaps = 21/281 (7%)
Query: 317 FIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEE 376
F+ R ++ + +KA+ G S D Q ELV +++ ++ S +KL + P
Sbjct: 1344 FLRPQRAALYILGDKAQLKGVRS-DPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPA 1402
Query: 377 TH-----WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 431
+L +LE + WL I +L ++ + + ++SG +SV+V DGWD T Q+ SL
Sbjct: 1403 AEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSG-SSVLVGLEDGWDITTQVVSLV 1461
Query: 432 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 491
L+ D +YRT+ GF +LVEKEWLSFGHRF R H + + +PVFLQF+DCV Q+
Sbjct: 1462 QLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQS-SGFTPVFLQFLDCVHQVH 1520
Query: 492 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSE----------QQRGKENLPKRTVSLW 541
QFP FEF++++L + H S F TFL +S+ +++G+ S+W
Sbjct: 1521 LQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGERRGQVPCRSVW 1580
Query: 542 SYI---NSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGY 579
Y+ + + F N +Y VL P +++ +L++W Y
Sbjct: 1581 EYVDRLSKRTPVFHNYMYAPEDAEVLRPYSNVSNLKVWDFY 1621
Score = 59.7 bits (143), Expect = 8e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 17/105 (16%)
Query: 222 NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATI 281
+E +RI+ +N Y +C +YP LL+VP ++ D L+RV+ + R PV+ W S+A +
Sbjct: 1147 SEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVL 1206
Query: 282 TR-----------------CSQPMVGVSGKRSKEDEKYLQAIMDS 309
R P + S E EKYLQA++ S
Sbjct: 1207 LRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSS 1251
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 144 bits (364), Expect = 2e-34
Identities = 148/555 (26%), Positives = 237/555 (42%), Gaps = 98/555 (17%)
Query: 55 DNFSPDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYF 114
+N P+ R + S+ LA LPGE I A V + GTL TN+R+ F
Sbjct: 26 ENRMPEPRSRQPSSCLASR----CLPGEQILAWAPGVRK--GLEPELSGTLICTNFRVTF 79
Query: 115 K----SMERDPPFVLDASLGVIN--RVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPE 168
+ +D P + ++N R+E + G S G ++ K I H +
Sbjct: 80 QPCGWQWNQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPG--SLHKFIPEEILIHGRD 137
Query: 169 GRTRRSIFE--NLMKYAFPVSNNLPLFAFEYKEVFPENGWKLYD------------PLLE 214
R R FE L AF V+ + + + +G L PL+E
Sbjct: 138 FRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPLME 197
Query: 215 Y------RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIP 268
R+ WR++ +NER+++ + P VP I D E++R +GR P
Sbjct: 198 TAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGP 257
Query: 269 VLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAV 328
LSW HP + + RC + +KED + ++ ++ A + + D + ++
Sbjct: 258 RLSWHHP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSL 312
Query: 329 ANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLEST 386
A D+ H+ +L+ + P ++ E WLS LE T
Sbjct: 313 A----------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGT 344
Query: 387 HWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFE 446
WL++++ L A I+ V S SV++ D L+SL L+ RT+ GF+
Sbjct: 345 RWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQ 404
Query: 447 VLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLI 506
LV++EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+
Sbjct: 405 SLVQREWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLL 460
Query: 507 TILDHLYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS--- 542
+ D + TFL N+ +RGK+ N +S+W
Sbjct: 461 ALHDSVRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDL 520
Query: 543 -YINSQLEDFTNPLY 556
Y N+Q+ F NP Y
Sbjct: 521 RYSNAQILQFQNPGY 535
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 144 bits (362), Expect = 3e-34
Identities = 126/435 (28%), Positives = 196/435 (45%), Gaps = 69/435 (15%)
Query: 155 CKDIRNLRFA--HKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVF-------PENG 205
CKD+R +F + E +R I ++ + LF F Y P+N
Sbjct: 143 CKDLRVFQFCLRYTKEEEVKR-IVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNH 201
Query: 206 WKLYDPLLEY-----RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVAS 260
++D L ++ R +G N ++ +NE Y++C+ PA VVP +P+E ++R
Sbjct: 202 TVMFDTLKDWCWELERTKG--NMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENVQR--- 256
Query: 261 FRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFD 320
F+ G IP+ W A + + P KE + + I S I+
Sbjct: 257 FQGHG-IPIWCWSCHNGSALLKMSALP---------KEQDDGILQIQKSFLDG--IYKTI 304
Query: 321 ARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEE---- 376
RP V ++ED N FL + I ++L + N E
Sbjct: 305 HRPPYEIV---------KTEDLSSN----FLSLQEIQTAYSKFKQL--FLIDNSTEFWDT 349
Query: 377 -THWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLML 435
W S LES+ WL+ I+ L A+ I + +E+ +V++ + D ++SL LM+
Sbjct: 350 DIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMM 409
Query: 436 DGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFP 495
D + RT GF+ L++KEW+ GH F R H +N D + PVFL F+DCVWQ+ Q P
Sbjct: 410 DPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQN--DKEEVPVFLLFLDCVWQLVHQHP 467
Query: 496 TAFEFNEYFLITILDHLYSCLFGTFLCNSEQQR----GKE-----NLPKRTVSLWSYINS 546
AFEF E +L + D LY +F TF NS Q+ G+E + P +++W + +
Sbjct: 468 PAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDW-SV 526
Query: 547 QLED-----FTNPLY 556
Q E NPLY
Sbjct: 527 QFEPKAQTLLKNPLY 541
Score = 31.6 bits (70), Expect = 2.4
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
Query: 531 ENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH------VLYPVASMRHLELWVGYYIRWN 584
+NL + +S + +L+D Y S+ + +L P +++W Y+RW
Sbjct: 588 KNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWI 647
Query: 585 PRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERASSPAQCV 636
P + + L+K E+ ++V+ LQ +I R S + + A C+
Sbjct: 648 PE---AQILGGGQVATLSKLLEMMEEVQSLQEKIDERH-HSQQAPQAEAPCL 695
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 141 bits (355), Expect = 2e-33
Identities = 105/370 (28%), Positives = 171/370 (46%), Gaps = 64/370 (17%)
Query: 214 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWI 273
E R+ WR++ +NER+++ + P VP I D E++R +GR P LSW
Sbjct: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
Query: 274 HPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAK 333
HP + + RC + +KED + ++ ++ A + + D + ++A
Sbjct: 191 HP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA---- 241
Query: 334 GGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEH 391
D+ H+ +L+ + P ++ E WLS LE T WL++
Sbjct: 242 ------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDY 277
Query: 392 IKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK 451
++ L A I+ V S SV++ D L+SL L+ RT+ GF+ LV++
Sbjct: 278 VRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQR 337
Query: 452 EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDH 511
EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D
Sbjct: 338 EWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDS 393
Query: 512 LYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS----YINS 546
+ TFL N+ +RGK+ N +S+W Y N+
Sbjct: 394 VRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNA 453
Query: 547 QLEDFTNPLY 556
Q+ F NP Y
Sbjct: 454 QILQFQNPGY 463
>gi|117938274 jumpy isoform 3 [Homo sapiens]
Length = 538
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 411 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 464
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 465 GHGDK 469
G++
Sbjct: 384 SKGEE 388
>gi|117938272 jumpy isoform 1 [Homo sapiens]
Length = 598
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 411 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 464
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 465 GHGDK 469
G++
Sbjct: 384 SKGEE 388
>gi|117938270 jumpy isoform 2 [Homo sapiens]
Length = 650
Score = 39.7 bits (91), Expect = 0.009
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 411 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 464
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 465 GHGDK 469
G++
Sbjct: 384 SKGEE 388
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 33.1 bits (74), Expect = 0.81
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 385 STHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLM 434
S HW +++ A+ D+ S K V+VHC G R+ +T +A LM
Sbjct: 299 SDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVT-VAYLM 347
>gi|22027646 angiomotin like 1 [Homo sapiens]
Length = 956
Score = 32.7 bits (73), Expect = 1.1
Identities = 17/53 (32%), Positives = 28/53 (52%)
Query: 19 PPSVDSLSSASTSHSENSVHTKSASVVSSDSISTSADNFSPDLRVLRESNKLA 71
PP +LSS +++ + +S H K+ S SS SA+ F P + L +L+
Sbjct: 848 PPPTSALSSIASTTAASSAHAKTGSKDSSTQTDKSAELFWPSMASLPSRGRLS 900
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 32.0 bits (71), Expect = 1.8
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 9 SLGSQPAAARPPSVDSLSSASTSHSENSVHTKSAS 43
+L QPA A+PPS S S T +N H +S+S
Sbjct: 356 ALDDQPAEAQPPSPRSSSPCRTPEPDNDAHLRSSS 390
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 32.0 bits (71), Expect = 1.8
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 9 SLGSQPAAARPPSVDSLSSASTSHSENSVHTKSAS 43
+L QPA A+PPS S S T +N H +S+S
Sbjct: 356 ALDDQPAEAQPPSPRSSSPCRTPEPDNDAHLRSSS 390
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 32.0 bits (71), Expect = 1.8
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 9 SLGSQPAAARPPSVDSLSSASTSHSENSVHTKSAS 43
+L QPA A+PPS S S T +N H +S+S
Sbjct: 356 ALDDQPAEAQPPSPRSSSPCRTPEPDNDAHLRSSS 390
>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
sapiens]
Length = 1050
Score = 32.0 bits (71), Expect = 1.8
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 596 RYKELLA---KRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQ 640
R ELL KRAE+QK++EE+++++ T+ ER + P +
Sbjct: 428 REAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTK 475
>gi|71774083 myc proto-oncogene protein [Homo sapiens]
Length = 454
Score = 31.6 bits (70), Expect = 2.4
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 5/66 (7%)
Query: 1 MEKSSSCESLGSQPAAARPPSVDSLSSASTSHSENS-----VHTKSASVVSSDSISTSAD 55
+ SSS +S SQ ++A PS DSL S++ S + S +H ++ SSDS D
Sbjct: 214 LNDSSSPKSCASQDSSAFSPSSDSLLSSTESSPQGSPEPLVLHEETPPTTSSDSEEEQED 273
Query: 56 NFSPDL 61
D+
Sbjct: 274 EEEIDV 279
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 31.6 bits (70), Expect = 2.4
Identities = 29/123 (23%), Positives = 51/123 (41%), Gaps = 10/123 (8%)
Query: 3 KSSSCESLGSQPAAARPPSV-------DSLSSASTSHSENSVHTKSASVVSSDSISTSAD 55
+ S + G + +PPSV D S+ TS + + ++A + D A
Sbjct: 163 EGSGGSTTGWRAREEQPPSVAEGYASQDVFSATETSLWYDFLPDQAAGLCGGDGRPRQA- 221
Query: 56 NFSPDLRVLRESNKLAEMEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFK 115
+ L VL +N + PPL+ G++ K A C +T +G +T Y K
Sbjct: 222 --TQRLSVLLCANADGSEKLPPLVAGKSAKPRAGQAGLPCDYTANSKGGVTTQALAKYLK 279
Query: 116 SME 118
+++
Sbjct: 280 ALD 282
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.396
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,669,854
Number of Sequences: 37866
Number of extensions: 1072796
Number of successful extensions: 4028
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 33
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 3926
Number of HSP's gapped (non-prelim): 78
length of query: 643
length of database: 18,247,518
effective HSP length: 109
effective length of query: 534
effective length of database: 14,120,124
effective search space: 7540146216
effective search space used: 7540146216
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.