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Search of human proteins with 44662817
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|44662817 IQ motif containing F2 [Homo sapiens]
(164 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44662817 IQ motif containing F2 [Homo sapiens] 340 2e-94
gi|229577354 IQ motif containing F1 [Homo sapiens] 156 7e-39
gi|222831628 IQ motif containing F5 [Homo sapiens] 142 2e-34
gi|146261997 IQ motif containing F3 [Homo sapiens] 122 1e-28
gi|254028213 IQ motif containing F6 [Homo sapiens] 115 2e-26
gi|20270345 spermatogenesis associated 17 [Homo sapiens] 43 1e-04
gi|197313718 IQ motif containing G [Homo sapiens] 42 2e-04
gi|14165288 IQ motif containing G [Homo sapiens] 42 2e-04
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 42 3e-04
gi|215982794 myosin VA isoform 2 [Homo sapiens] 40 7e-04
gi|215982791 myosin VA isoform 1 [Homo sapiens] 40 7e-04
gi|124494247 myosin IC isoform b [Homo sapiens] 40 0.001
gi|124494238 myosin IC isoform a [Homo sapiens] 40 0.001
gi|124494240 myosin IC isoform c [Homo sapiens] 40 0.001
gi|156119615 myosin IXA [Homo sapiens] 39 0.002
gi|194272142 myosin IXB isoform 2 [Homo sapiens] 39 0.003
gi|33356170 myosin IXB isoform 1 [Homo sapiens] 39 0.003
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 37 0.006
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 37 0.006
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 37 0.006
gi|122937512 myosin VIIB [Homo sapiens] 37 0.010
gi|55956786 spindle assembly associated Sfi1 homolog isoform a [... 36 0.013
gi|55956784 spindle assembly associated Sfi1 homolog isoform b [... 36 0.013
gi|39753961 IQ motif containing GTPase activating protein 3 [Hom... 36 0.013
gi|116089337 IQ motif containing GTPase activating protein 2 [Ho... 36 0.013
gi|224451032 KIAA1683 isoform a [Homo sapiens] 36 0.017
gi|224451036 KIAA1683 isoform c [Homo sapiens] 36 0.017
gi|54606862 KIAA1683 isoform b [Homo sapiens] 36 0.017
gi|122937315 leucine-rich repeats and IQ motif containing 4 [Hom... 35 0.038
gi|120953300 leucine-rich repeats and IQ motif containing 1 isof... 33 0.14
>gi|44662817 IQ motif containing F2 [Homo sapiens]
Length = 164
Score = 340 bits (873), Expect = 2e-94
Identities = 164/164 (100%), Positives = 164/164 (100%)
Query: 1 MRVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVR 60
MRVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVR
Sbjct: 1 MRVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVR 60
Query: 61 RTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYC 120
RTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYC
Sbjct: 61 RTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYC 120
Query: 121 QVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEIINS 164
QVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEIINS
Sbjct: 121 QVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEIINS 164
>gi|229577354 IQ motif containing F1 [Homo sapiens]
Length = 205
Score = 156 bits (395), Expect = 7e-39
Identities = 76/151 (50%), Positives = 104/151 (68%), Gaps = 4/151 (2%)
Query: 12 ILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAW 71
+LV + V+ + E + Q+K+ +K + TK IQAWWRGTLVRR LLHAAL A
Sbjct: 41 VLVETQTVDNANEKSEKPPENQKKLSDKDTVATK----IQAWWRGTLVRRALLHAALSAC 96
Query: 72 IIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQG 131
IIQCWWR+ LS++L+K+RQAAL A++ +E A + LQS RMWR+R RYCQVLNA+ IIQ
Sbjct: 97 IIQCWWRLILSKILKKRRQAALEAFSRKEWAAVTLQSQARMWRIRRRYCQVLNAVRIIQA 156
Query: 132 HWQCHNCQTCALLQGHCVVTATHLQFHIEII 162
+W+C +C + ++G VTA L +EI+
Sbjct: 157 YWRCRSCASRGFIKGQYRVTANQLHLQLEIL 187
>gi|222831628 IQ motif containing F5 [Homo sapiens]
Length = 148
Score = 142 bits (357), Expect = 2e-34
Identities = 65/116 (56%), Positives = 83/116 (71%)
Query: 46 AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIK 105
AAV IQAWWRG LVRRTLLHAALRAWIIQCWWR L ++L K+R+ L Y +E A ++
Sbjct: 14 AAVFIQAWWRGMLVRRTLLHAALRAWIIQCWWRQVLEKLLAKRRRMVLEFYVQQEWAAVR 73
Query: 106 LQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEI 161
LQS VRMW VR RYC++LNA+ IIQ +W+ H+C + ++GH + L +EI
Sbjct: 74 LQSWVRMWCVRQRYCRLLNAVRIIQVYWRWHSCHSRVFIEGHYELKENQLNIQLEI 129
Score = 27.3 bits (59), Expect = 6.1
Identities = 16/51 (31%), Positives = 26/51 (50%)
Query: 28 LQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
L K+++ + E + AAV++Q+W R VR+ IIQ +WR
Sbjct: 52 LLAKRRRMVLEFYVQQEWAAVRLQSWVRMWCVRQRYCRLLNAVRIIQVYWR 102
>gi|146261997 IQ motif containing F3 [Homo sapiens]
Length = 154
Score = 122 bits (307), Expect = 1e-28
Identities = 64/144 (44%), Positives = 91/144 (63%), Gaps = 2/144 (1%)
Query: 20 EESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRM 79
E+++E + QK ++ + R+ KAA +IQAWWRG LVRRTLL AALRAW+IQCWWR
Sbjct: 12 EDAVERQRRQKLLLAQLHHRKRV--KAAGQIQAWWRGVLVRRTLLVAALRAWMIQCWWRT 69
Query: 80 TLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQ 139
+ R + ++RQA L Y +E+A +KLQS +RMW+ R Y Q+ NA+ + Q Q
Sbjct: 70 LVQRRIRQRRQALLRVYVIQEQATVKLQSCIRMWQCRQCYRQMCNALCLFQVPESSLAFQ 129
Query: 140 TCALLQGHCVVTATHLQFHIEIIN 163
T LQ + + +FHIEI++
Sbjct: 130 TDGFLQVQYAIPSKQPEFHIEILS 153
>gi|254028213 IQ motif containing F6 [Homo sapiens]
Length = 107
Score = 115 bits (287), Expect = 2e-26
Identities = 54/105 (51%), Positives = 74/105 (70%)
Query: 58 LVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRW 117
+VRRTLL AALRAW+IQCWWR +++LE++R+ AL Y +E AV+K+Q+ VRMW+ R
Sbjct: 1 MVRRTLLQAALRAWVIQCWWRSMQAKMLEQRRRLALRLYTCQEWAVVKVQAQVRMWQARR 60
Query: 118 RYCQVLNAIYIIQGHWQCHNCQTCALLQGHCVVTATHLQFHIEII 162
R+ Q A IIQ HW+ H QT L++GH V A+ L+ IEI+
Sbjct: 61 RFLQARQAACIIQSHWRWHASQTRGLIRGHYEVRASRLELDIEIL 105
Score = 32.7 bits (73), Expect = 0.14
Identities = 24/63 (38%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 25 WKTLQKKK-QQKIKEKLRIRTK---AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMT 80
W+++Q K +Q+ + LR+ T A VK+QA R RR L A A IIQ WR
Sbjct: 20 WRSMQAKMLEQRRRLALRLYTCQEWAVVKVQAQVRMWQARRRFLQARQAACIIQSHWRWH 79
Query: 81 LSR 83
S+
Sbjct: 80 ASQ 82
>gi|20270345 spermatogenesis associated 17 [Homo sapiens]
Length = 361
Score = 43.1 bits (100), Expect = 1e-04
Identities = 28/76 (36%), Positives = 39/76 (51%), Gaps = 7/76 (9%)
Query: 46 AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATR-----E 100
AAVKIQ+W+RG VR + H IIQ WWR L R ++ + +AY T
Sbjct: 35 AAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGR--KQYQLTVQVAYYTMMMNLYN 92
Query: 101 RAVIKLQSLVRMWRVR 116
+++Q R +RVR
Sbjct: 93 AMAVRIQRRWRGYRVR 108
>gi|197313718 IQ motif containing G [Homo sapiens]
Length = 443
Score = 42.0 bits (97), Expect = 2e-04
Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 1/54 (1%)
Query: 10 NLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTL 63
+L +I E + IE + +++ ++K+K+ L + K+ +K+QAWWRGT++RR +
Sbjct: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIKLQAWWRGTMIRREI 413
>gi|14165288 IQ motif containing G [Homo sapiens]
Length = 443
Score = 42.0 bits (97), Expect = 2e-04
Identities = 19/54 (35%), Positives = 37/54 (68%), Gaps = 1/54 (1%)
Query: 10 NLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTL 63
+L +I E + IE + +++ ++K+K+ L + K+ +K+QAWWRGT++RR +
Sbjct: 361 DLAKMIREYEQVIIEDRIEKERSKKKVKQDL-LELKSVIKLQAWWRGTMIRREI 413
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 41.6 bits (96), Expect = 3e-04
Identities = 45/151 (29%), Positives = 66/151 (43%), Gaps = 20/151 (13%)
Query: 2 RVRFCTKGNLILVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRR 61
R R T N + I + V++ W ++ Q + KLR + + IQA +RG RR
Sbjct: 2202 RYRQQTYFNKLKKITKTVQQRY-WAMKERNIQFQRYNKLR---HSVIYIQAIFRGKKARR 2257
Query: 62 TLLHAALRAWIIQCWWR--MTLSRVLEKKRQAALIAYATR--------------ERAVIK 105
L + A +IQ +R M R L K+ A LI R + AVIK
Sbjct: 2258 HLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIK 2317
Query: 106 LQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
+QS R W +R R ++ A IQ ++ H
Sbjct: 2318 IQSSYRRWMIRKRMREMHRAATFIQSTFRMH 2348
Score = 41.2 bits (95), Expect = 4e-04
Identities = 36/109 (33%), Positives = 50/109 (45%), Gaps = 19/109 (17%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALR---------AWIIQCWWRMTLSRVLEK 87
K++LR R AA+ IQ +WR L +R LL A +IQ +WR R +
Sbjct: 1309 KQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWR----RYSTR 1364
Query: 88 KRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
+R L Y+ I LQS +RM Y + L A IQ HW+ +
Sbjct: 1365 QRFLKLKYYS------IILQSRIRMIIAVTSYKRYLWATVTIQRHWRAY 1407
Score = 40.8 bits (94), Expect = 5e-04
Identities = 31/102 (30%), Positives = 51/102 (50%), Gaps = 15/102 (14%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAY 96
KE L ++ K A+KIQ+ +RG VRR + H A I+ ++M SR I+Y
Sbjct: 2088 KEYLNLK-KTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSR----------ISY 2136
Query: 97 ATRERAVIKLQSLVRMW----RVRWRYCQVLNAIYIIQGHWQ 134
T +A I +Q R + R +Y +L A+ ++Q ++
Sbjct: 2137 HTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFR 2178
Score = 40.4 bits (93), Expect = 7e-04
Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 16/115 (13%)
Query: 27 TLQKKKQQKIKEKLRI-----RTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTL 81
T+QK + +K K+ + AA+++QA +R L L A +IQ +WRM
Sbjct: 1516 TIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFR-RLKAHNLCRQIRAACVIQSYWRMRQ 1574
Query: 82 SRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
RV + ++ +IK Q+ VR + R +Y ++ A IIQ H++ +
Sbjct: 1575 DRV----------RFLNLKKTIIKFQAHVRKHQQRQKYKKMKKAAVIIQTHFRAY 1619
Score = 40.0 bits (92), Expect = 0.001
Identities = 21/81 (25%), Positives = 46/81 (56%), Gaps = 10/81 (12%)
Query: 33 QQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
Q++ ++ +RT+A + IQ+++RG VR+ + + A +IQ ++RM A
Sbjct: 2655 QRRYRKLTAVRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRM----------HRA 2704
Query: 93 LIAYATRERAVIKLQSLVRMW 113
+ Y T++ A++ +Q+ R++
Sbjct: 2705 KVDYETKKTAIVVIQNYYRLY 2725
Score = 38.1 bits (87), Expect = 0.003
Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 22/122 (18%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKR------- 89
KE L ++ A +K+Q+ + R+ LH A IQ +R ++ +KR
Sbjct: 1673 KEFLSLKN-ATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRS--KKIAAQKREEYMQMR 1729
Query: 90 ------QAALIAYATRE------RAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHN 137
QA + Y R+ +AVI LQS RM + R Y ++ AI +IQ ++ +
Sbjct: 1730 ESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKARQYYLKMYKAIIVIQNYYHAYK 1789
Query: 138 CQ 139
Q
Sbjct: 1790 AQ 1791
Score = 38.1 bits (87), Expect = 0.003
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 14/104 (13%)
Query: 28 LQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEK 87
L K Q+++ ++R + + IQA +G + +R IQ WR R K
Sbjct: 2897 LSAKHQRQVYLQIR---SSVIIIQARSKGFIQKRKFQEIKNSTIKIQAMWR----RYRAK 2949
Query: 88 KRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQG 131
K Y + +A K+Q+ R WR Y +L A+ IIQG
Sbjct: 2950 K-------YLCKVKAACKIQAWYRCWRAHKEYLAILKAVKIIQG 2986
Score = 35.4 bits (80), Expect = 0.022
Identities = 36/151 (23%), Positives = 64/151 (42%), Gaps = 19/151 (12%)
Query: 29 QKKKQQKIKEKL-RIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEK 87
Q+K KEKL +++ KAA IQ +WR R+ L + I+Q RM ++ K
Sbjct: 1332 QRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYK 1391
Query: 88 KRQAALIAYATRERAVIK-----------------LQSLVRMWRVRWRYCQVLNAIYIIQ 130
+ A + RA ++ +QS+ R W+ R QV A I+Q
Sbjct: 1392 RYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQV-KATVILQ 1450
Query: 131 GHWQCHNCQTCALLQGHCVVTATHLQFHIEI 161
++ + + A + ++ + + H E+
Sbjct: 1451 RAFREWHLRKQAKEENSAIIIQSWYRMHKEL 1481
Score = 35.4 bits (80), Expect = 0.022
Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 43 RTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRERA 102
R +AA IQA +RG R+ L A IIQ + R + E+ I Y +++
Sbjct: 3029 RHRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHER------IKYIEFKKS 3082
Query: 103 VIKLQSLVRMWRVRWRYCQ 121
+ LQ+LVR W VR R+ +
Sbjct: 3083 TVILQALVRGWLVRKRFLE 3101
Score = 35.0 bits (79), Expect = 0.029
Identities = 30/112 (26%), Positives = 54/112 (48%), Gaps = 9/112 (8%)
Query: 27 TLQKK-KQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR-MTLSRV 84
TLQ + K++++++ KAAV IQ+ +R ++ A IIQ W+R + ++
Sbjct: 2026 TLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNH 2085
Query: 85 LEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
K+ Y ++ IK+QS+ R RVR + A I+ ++ H
Sbjct: 2086 QHKE-------YLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMH 2130
Score = 34.7 bits (78), Expect = 0.038
Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 17/108 (15%)
Query: 46 AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEK--KRQAALI--------- 94
A + +Q+ W+G +RR L A IIQ ++RM + + K K+ A LI
Sbjct: 1950 AVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSI 2009
Query: 95 ------AYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
Y + AV+ LQS R +VR R A IQ ++ +
Sbjct: 2010 GREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAY 2057
Score = 33.1 bits (74), Expect = 0.11
Identities = 33/121 (27%), Positives = 56/121 (46%), Gaps = 24/121 (19%)
Query: 13 LVIIEDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWI 72
+++I++ + + + Q+K ++K KAA +QA +RG VR+ + ++ A
Sbjct: 1778 IIVIQNYYHAYKAQVNQRKNFLQVK-------KAATCLQAAYRGYKVRQLIKQQSIAALK 1830
Query: 73 IQCWWRMTLSRVLEKKRQAALI-------AYAT----------RERAVIKLQSLVRMWRV 115
IQ +R RV + ++I AY T + AVI LQS R W+V
Sbjct: 1831 IQSAFRGYNKRVKYQSVLQSIIKIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKV 1890
Query: 116 R 116
R
Sbjct: 1891 R 1891
Score = 32.3 bits (72), Expect = 0.19
Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 34/142 (23%)
Query: 24 EWKTLQKKKQQKIKEK-----------LRIRTK---AAVKIQAWWRGTLVRRTLLHAALR 69
+WK Q+K Q ++K LR + K +A+ IQ+W+R R ++
Sbjct: 1433 KWK--QRKMQSQVKATVILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSC 1490
Query: 70 AWIIQCWWRMTLSRVLEKKRQAALIA-----------------YATRERAVIKLQSLVRM 112
IIQ +R ++ L K+R+ +++ Y + A I+LQ+ R
Sbjct: 1491 VVIIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRR 1550
Query: 113 WRVRWRYCQVLNAIYIIQGHWQ 134
+ C+ + A +IQ +W+
Sbjct: 1551 LKAH-NLCRQIRAACVIQSYWR 1571
Score = 31.6 bits (70), Expect = 0.32
Identities = 29/111 (26%), Positives = 48/111 (43%), Gaps = 19/111 (17%)
Query: 46 AAVKIQAWWRGTLVRRT------LLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAY--- 96
A V IQ WR L R+ +L ++ IIQ +R R ++ + +A +I
Sbjct: 1396 ATVTIQRHWRAYLRRKQDQQRYEMLKSS--TLIIQSMFRKWKQRKMQSQVKATVILQRAF 1453
Query: 97 --------ATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQ 139
A E + I +QS RM + +Y + + + IIQ ++C Q
Sbjct: 1454 REWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQ 1504
Score = 31.6 bits (70), Expect = 0.32
Identities = 29/125 (23%), Positives = 56/125 (44%), Gaps = 16/125 (12%)
Query: 42 IRTKAAV-KIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAALIAYATRE 100
++TKAAV +Q+ +RG VR+ + A IQ +RM K Q + T
Sbjct: 1872 LKTKAAVISLQSAYRGWKVRKQIRREHQAALKIQSAFRMA-------KAQKQFRLFKT-- 1922
Query: 101 RAVIKLQSLVRMWRVRWRYC----QVLNAIYIIQGHWQCHNCQTCALLQGHC-VVTATHL 155
A + +Q R W + C ++ +A+ ++Q W+ + Q C ++ ++
Sbjct: 1923 -AALVIQQNFRAWTAGRKQCMEYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYY 1981
Query: 156 QFHIE 160
+ H++
Sbjct: 1982 RMHVQ 1986
Score = 31.2 bits (69), Expect = 0.42
Identities = 23/85 (27%), Positives = 44/85 (51%), Gaps = 5/85 (5%)
Query: 33 QQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
+ K+ + L +R KAA+ IQ+ +R +V++ L A +IQ +RM + + + + A
Sbjct: 2448 KHKLYQFLHLR-KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHA 2506
Query: 93 LIA----YATRERAVIKLQSLVRMW 113
I Y T A ++ ++ +R W
Sbjct: 2507 SILIQQHYRTYRAAKLQRENYIRQW 2531
Score = 31.2 bits (69), Expect = 0.42
Identities = 28/108 (25%), Positives = 52/108 (48%), Gaps = 15/108 (13%)
Query: 32 KQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQA 91
+ IK++++ + +AA+ IQ + +R+ LH LRA ++ ++R
Sbjct: 2613 QDMNIKKQIQEQHQAAIIIQKHCKAFKIRKHYLH--LRATVVSI-----------QRRYR 2659
Query: 92 ALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQ 139
L A R +AVI +QS R ++VR + A +IQ ++ H +
Sbjct: 2660 KLTA--VRTQAVICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAK 2705
Score = 30.8 bits (68), Expect = 0.55
Identities = 26/103 (25%), Positives = 48/103 (46%), Gaps = 16/103 (15%)
Query: 48 VKIQAWWRGTLV---RRTLLHAALRAWI-IQCWWRMTLSRVLEKKRQAALIA-------- 95
V IQ W++ + + + H+ RA + IQ + ++R LE ++ AAL
Sbjct: 2792 VMIQEWYKASGLACSQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAV 2851
Query: 96 ----YATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQ 134
+ ++RA I LQ R W+ R ++ A ++Q H++
Sbjct: 2852 YRRRFVQQKRAAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYR 2894
Score = 30.4 bits (67), Expect = 0.72
Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 34/137 (24%)
Query: 28 LQKKKQQKIK---------------EKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWI 72
+QK+K Q+IK +K + KAA KIQAW+R + L I
Sbjct: 2924 IQKRKFQEIKNSTIKIQAMWRRYRAKKYLCKVKAACKIQAWYRCWRAHKEYLAILKAVKI 2983
Query: 73 IQCWWRMTLSR-----------VLEKKRQAALIA--------YATRERAVIKLQSLVRMW 113
IQ + L R ++++K +A L A R RA +Q+ R +
Sbjct: 2984 IQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAKIAHEHFLMIKRHRAACLIQAHYRGY 3043
Query: 114 RVRWRYCQVLNAIYIIQ 130
+ R + + +A IIQ
Sbjct: 3044 KGRQVFLRQKSAALIIQ 3060
Score = 30.0 bits (66), Expect = 0.94
Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 16/119 (13%)
Query: 34 QKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRV--------- 84
+K + L++ AA IQ +R ++RR L A +IQ +R L
Sbjct: 2253 KKARRHLKMMHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQ 2312
Query: 85 -----LEKKRQAALIAYATRE--RAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
++ + +I RE RA +QS RM R+ RY + A +IQ +Q +
Sbjct: 2313 NAVIKIQSSYRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQAN 2371
Score = 29.6 bits (65), Expect = 1.2
Identities = 28/119 (23%), Positives = 51/119 (42%), Gaps = 17/119 (14%)
Query: 35 KIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMT------LSRVLEKK 88
K + L+ +A IQ+ +R LVRR + +Q +R T L + L +
Sbjct: 2399 KTRRHLKSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLR 2458
Query: 89 RQAALIAYATR-----------ERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCH 136
+ A I + R +RA + +Q+ RM+R + +A +IQ H++ +
Sbjct: 2459 KAAITIQSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTY 2517
Score = 27.7 bits (60), Expect = 4.6
Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 18/126 (14%)
Query: 29 QKKKQQKIKEKLRIRTK-AAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSR---- 83
Q + K++ + +R + +AV +QA +RG RR L A +IQ +R L R
Sbjct: 2369 QANRAAKLQRQHYLRQRHSAVILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRRFI 2428
Query: 84 -------VLEKKRQAALIA------YATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQ 130
+++K +A + A + +A I +QS R V+ + ++ A +IQ
Sbjct: 2429 SLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITIQSSYRRLMVKKKLQEMQRAAVLIQ 2488
Query: 131 GHWQCH 136
++ +
Sbjct: 2489 ATFRMY 2494
Score = 27.3 bits (59), Expect = 6.1
Identities = 24/104 (23%), Positives = 46/104 (44%), Gaps = 6/104 (5%)
Query: 27 TLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLE 86
T+QK + + KL + AA++IQ + + + RR + A +Q ++R +R
Sbjct: 2820 TIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKRAAITLQHYFRTWQTRKQF 2879
Query: 87 KKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQ 130
+ A + RA + + R Y Q+ +++ IIQ
Sbjct: 2880 LLYRKAAVVLQNHYRAFLSAK------HQRQVYLQIRSSVIIIQ 2917
Score = 26.9 bits (58), Expect = 7.9
Identities = 17/42 (40%), Positives = 22/42 (52%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
+EK KA +QA +RG VRRTL A +IQ +R
Sbjct: 2160 REKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYR 2201
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 40.4 bits (93), Expect = 7e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 33 QQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
Q + K RTKAA IQ +WR +VRR ++Q + R L+R +K
Sbjct: 804 QARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK---- 859
Query: 93 LIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQ 130
RE + +Q VR W R Y + ++AI +Q
Sbjct: 860 ----ILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQ 893
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 40.4 bits (93), Expect = 7e-04
Identities = 30/98 (30%), Positives = 44/98 (44%), Gaps = 8/98 (8%)
Query: 33 QQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
Q + K RTKAA IQ +WR +VRR ++Q + R L+R +K
Sbjct: 804 QARCYAKFLRRTKAATIIQKYWRMYVVRRRYKIRRAATIVLQSYLRGFLARNRYRK---- 859
Query: 93 LIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQ 130
RE + +Q VR W R Y + ++AI +Q
Sbjct: 860 ----ILREHKAVIIQKRVRGWLARTHYKRSMHAIIYLQ 893
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 43 RTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
R A KIQA WRG R+ L A IQ WWR TL R KR+ A
Sbjct: 715 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 764
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 43 RTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
R A KIQA WRG R+ L A IQ WWR TL R KR+ A
Sbjct: 734 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 783
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 40.0 bits (92), Expect = 0.001
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 43 RTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAA 92
R A KIQA WRG R+ L A IQ WWR TL R KR+ A
Sbjct: 699 RQSLATKIQAAWRGFHWRQKFLRVKRSAICIQSWWRGTLGRRKAAKRKWA 748
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 39.3 bits (90), Expect = 0.002
Identities = 28/108 (25%), Positives = 53/108 (49%), Gaps = 2/108 (1%)
Query: 28 LQKKKQQKIKEKLRIRT-KAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLE 86
L+++++Q +++ L + + +Q W+R L R+ LH + IIQ +WR L++
Sbjct: 1003 LKEQERQHLQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQV 1062
Query: 87 KKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQ 134
+ A+ A + LQ+ R R RY ++ A +IQ W+
Sbjct: 1063 RDAAVQKDAFVMASAAAL-LQASWRAHLERQRYLELRAAAIVIQQKWR 1109
>gi|194272142 myosin IXB isoform 2 [Homo sapiens]
Length = 2022
Score = 38.5 bits (88), Expect = 0.003
Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 13/110 (11%)
Query: 28 LQKKKQQKIKEKL-RIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQ-CWWRMTLSRVL 85
L++ ++Q ++E L R + + +Q+W+R L RR L A IQ CW + R L
Sbjct: 940 LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRAL 999
Query: 86 EKKRQAALI-----------AYATRERAVIKLQSLVRMWRVRWRYCQVLN 124
E+ + A + Y +++++I+LQSL R R + Q+++
Sbjct: 1000 ERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMIS 1049
Score = 34.7 bits (78), Expect = 0.038
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Query: 17 EDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCW 76
E + +E + K+ Q K K+ ++ +Q +VR+ LL +Q W
Sbjct: 915 EVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILL--------LQSW 966
Query: 77 WRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYI---IQGHW 133
+RM VLE++ + +RA + +Q+ R +RVR + A+Y+ +G+W
Sbjct: 967 FRM----VLERRH------FLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYW 1016
Query: 134 Q----CHNCQTCALLQGHC 148
Q H Q+ LQ C
Sbjct: 1017 QRKLYRHQKQSIIRLQSLC 1035
>gi|33356170 myosin IXB isoform 1 [Homo sapiens]
Length = 2157
Score = 38.5 bits (88), Expect = 0.003
Identities = 30/110 (27%), Positives = 55/110 (50%), Gaps = 13/110 (11%)
Query: 28 LQKKKQQKIKEKL-RIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQ-CWWRMTLSRVL 85
L++ ++Q ++E L R + + +Q+W+R L RR L A IQ CW + R L
Sbjct: 940 LKETERQALQETLHREVVRKILLLQSWFRMVLERRHFLQMKRAAVTIQACWRSYRVRRAL 999
Query: 86 EKKRQAALI-----------AYATRERAVIKLQSLVRMWRVRWRYCQVLN 124
E+ + A + Y +++++I+LQSL R R + Q+++
Sbjct: 1000 ERTQAAVYLQASWRGYWQRKLYRHQKQSIIRLQSLCRGHLQRKSFSQMIS 1049
Score = 34.7 bits (78), Expect = 0.038
Identities = 35/139 (25%), Positives = 61/139 (43%), Gaps = 25/139 (17%)
Query: 17 EDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCW 76
E + +E + K+ Q K K+ ++ +Q +VR+ LL +Q W
Sbjct: 915 EVISTLLEKMKIDKRNYQIGKTKVFLKETERQALQETLHREVVRKILL--------LQSW 966
Query: 77 WRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYI---IQGHW 133
+RM VLE++ + +RA + +Q+ R +RVR + A+Y+ +G+W
Sbjct: 967 FRM----VLERRH------FLQMKRAAVTIQACWRSYRVRRALERTQAAVYLQASWRGYW 1016
Query: 134 Q----CHNCQTCALLQGHC 148
Q H Q+ LQ C
Sbjct: 1017 QRKLYRHQKQSIIRLQSLC 1035
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 37.4 bits (85), Expect = 0.006
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 5/67 (7%)
Query: 77 WRMTLSRVLEKKRQAALIAYATRERA----VIKLQSLVRMWRVRWRYCQVLNAIYIIQGH 132
W++ +++ K L+ R++A VI LQ ++R ++ R + ++ NA +IQ H
Sbjct: 719 WQIGKTKIFLKDHHDMLLE-VERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRH 777
Query: 133 WQCHNCQ 139
W+ HNC+
Sbjct: 778 WRGHNCR 784
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 37.4 bits (85), Expect = 0.006
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 5/67 (7%)
Query: 77 WRMTLSRVLEKKRQAALIAYATRERA----VIKLQSLVRMWRVRWRYCQVLNAIYIIQGH 132
W++ +++ K L+ R++A VI LQ ++R ++ R + ++ NA +IQ H
Sbjct: 719 WQIGKTKIFLKDHHDMLLE-VERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRH 777
Query: 133 WQCHNCQ 139
W+ HNC+
Sbjct: 778 WRGHNCR 784
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 37.4 bits (85), Expect = 0.006
Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 5/67 (7%)
Query: 77 WRMTLSRVLEKKRQAALIAYATRERA----VIKLQSLVRMWRVRWRYCQVLNAIYIIQGH 132
W++ +++ K L+ R++A VI LQ ++R ++ R + ++ NA +IQ H
Sbjct: 719 WQIGKTKIFLKDHHDMLLE-VERDKAITDRVILLQKVIRGFKDRSNFLKLKNAATLIQRH 777
Query: 133 WQCHNCQ 139
W+ HNC+
Sbjct: 778 WRGHNCR 784
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 36.6 bits (83), Expect = 0.010
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 15/109 (13%)
Query: 38 EKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSR-------------- 83
++ ++ +AA+ IQ RG R+ L A +Q WWR +R
Sbjct: 758 QRSQVLDRAALSIQKVLRGYRYRKEFLRQRRAAVTLQAWWRGYCNRRNFKLILVGFERLQ 817
Query: 84 VLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGH 132
+ + + A A R+R V +LQ+L R + VR + A+ +IQ H
Sbjct: 818 AIARSQPLARQYQAMRQRTV-QLQALCRGYLVRQQVQAKRRAVVVIQAH 865
>gi|55956786 spindle assembly associated Sfi1 homolog isoform a
[Homo sapiens]
Length = 1242
Score = 36.2 bits (82), Expect = 0.013
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 17/126 (13%)
Query: 25 WKTLQKKKQQKIKEKLRIRTK-AAVKIQAWWRGTL----VRRTLLHAALRAW------II 73
WKT +++Q+ + +R A K++ W+ L VRRT L A I+
Sbjct: 161 WKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIIL 220
Query: 74 QCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQ-----VLNAIYI 128
+ WW R+ + + AL A A + RA+ WR + Y Q V++A+
Sbjct: 221 RVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKH 280
Query: 129 IQGHWQ 134
Q HWQ
Sbjct: 281 HQ-HWQ 285
>gi|55956784 spindle assembly associated Sfi1 homolog isoform b
[Homo sapiens]
Length = 1211
Score = 36.2 bits (82), Expect = 0.013
Identities = 35/126 (27%), Positives = 55/126 (43%), Gaps = 17/126 (13%)
Query: 25 WKTLQKKKQQKIKEKLRIRTK-AAVKIQAWWRGTL----VRRTLLHAALRAW------II 73
WKT +++Q+ + +R A K++ W+ L VRRT L A I+
Sbjct: 161 WKTYVRQQQEMRNKYIRAEVHDAKQKMRQAWKSWLIYVVVRRTKLQMQTTALEFRQRIIL 220
Query: 74 QCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQ-----VLNAIYI 128
+ WW R+ + + AL A A + RA+ WR + Y Q V++A+
Sbjct: 221 RVWWSTWRQRLGQVRVSRALHASALKHRALSLQVQAWSQWREQLLYVQKEKQKVVSAVKH 280
Query: 129 IQGHWQ 134
Q HWQ
Sbjct: 281 HQ-HWQ 285
>gi|39753961 IQ motif containing GTPase activating protein 3 [Homo
sapiens]
Length = 1631
Score = 36.2 bits (82), Expect = 0.013
Identities = 36/137 (26%), Positives = 60/137 (43%), Gaps = 21/137 (15%)
Query: 17 EDVEESIEWKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAA--LRAWI-- 72
E+++ ++ T +QQ K + +++QA RG LVR+ + LR W+
Sbjct: 708 EEIQSAVTKVTAAYDRQQLWKANVGF----VIQLQARLRGFLVRQKFAEHSHFLRTWLPA 763
Query: 73 ---IQCWWRMTLSRVLEKKRQAALIAYATRERAVIKLQSLVRMWRVRWRYCQVL------ 123
IQ WR R + + L + A+IK+Q+ RMW R +Y + L
Sbjct: 764 VIKIQAHWRGYRQRKIYLEW---LQYFKANLDAIIKIQAWARMWAARRQYLRRLHYFQKN 820
Query: 124 -NAIYIIQGHWQCHNCQ 139
N+I IQ ++ Q
Sbjct: 821 VNSIVKIQAFFRARKAQ 837
>gi|116089337 IQ motif containing GTPase activating protein 2 [Homo
sapiens]
Length = 1575
Score = 36.2 bits (82), Expect = 0.013
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 12/91 (13%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWI--------IQCWWRMTLSRVLEKK 88
K L + + VKIQA+W+G R+ +H + +I IQ W+RM +R K
Sbjct: 684 KSFLHEQEENVVKIQAFWKGYKQRKEYMHRR-QTFIDNTDSIVKIQSWFRMATAR---KS 739
Query: 89 RQAALIAYATRERAVIKLQSLVRMWRVRWRY 119
+ L + ++K+QSL+R + R Y
Sbjct: 740 YLSRLQYFRDHNNEIVKIQSLLRANKARDDY 770
>gi|224451032 KIAA1683 isoform a [Homo sapiens]
Length = 1367
Score = 35.8 bits (81), Expect = 0.017
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
+ ++R+ + A+ IQA WRG VRR L H IQ WR
Sbjct: 1130 RRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWR 1171
Score = 33.9 bits (76), Expect = 0.065
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 45 KAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAAL 93
KAA IQ+ WRG +R+ + + A I+Q WR +R K +A L
Sbjct: 1302 KAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSCLKNTEALL 1350
Score = 30.0 bits (66), Expect = 0.94
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 29 QKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
Q K + E + +AA IQA WRG +R+ L+ + A IQ WR
Sbjct: 89 QAFKNILVDEMDMMHARAATLIQANWRGYWLRQKLISQMMAAKAIQEAWR 138
Score = 27.7 bits (60), Expect = 4.6
Identities = 12/43 (27%), Positives = 25/43 (58%)
Query: 99 RERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTC 141
+++A +QS R +++R + Q A I+Q W+ H+ ++C
Sbjct: 1300 QDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSC 1342
Score = 27.3 bits (59), Expect = 6.1
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 42 IRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
IR A + IQA RG L RR + A +IQ WR
Sbjct: 1112 IRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWR 1148
>gi|224451036 KIAA1683 isoform c [Homo sapiens]
Length = 1134
Score = 35.8 bits (81), Expect = 0.017
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
+ ++R+ + A+ IQA WRG VRR L H IQ WR
Sbjct: 897 RRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWR 938
Score = 33.9 bits (76), Expect = 0.065
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 45 KAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAAL 93
KAA IQ+ WRG +R+ + + A I+Q WR +R K +A L
Sbjct: 1069 KAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSCLKNTEALL 1117
Score = 30.0 bits (66), Expect = 0.94
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 29 QKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
Q K + E + +AA IQA WRG +R+ L+ + A IQ WR
Sbjct: 43 QAFKNILVDEMDMMHARAATLIQANWRGYWLRQKLISQMMAAKAIQEAWR 92
Score = 27.7 bits (60), Expect = 4.6
Identities = 12/43 (27%), Positives = 25/43 (58%)
Query: 99 RERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTC 141
+++A +QS R +++R + Q A I+Q W+ H+ ++C
Sbjct: 1067 QDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSC 1109
Score = 27.3 bits (59), Expect = 6.1
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 42 IRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
IR A + IQA RG L RR + A +IQ WR
Sbjct: 879 IRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWR 915
>gi|54606862 KIAA1683 isoform b [Homo sapiens]
Length = 1180
Score = 35.8 bits (81), Expect = 0.017
Identities = 17/42 (40%), Positives = 23/42 (54%)
Query: 37 KEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
+ ++R+ + A+ IQA WRG VRR L H IQ WR
Sbjct: 943 RRRIRLWHRGAMVIQATWRGYRVRRNLAHLCRATTTIQSAWR 984
Score = 33.9 bits (76), Expect = 0.065
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 45 KAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWRMTLSRVLEKKRQAAL 93
KAA IQ+ WRG +R+ + + A I+Q WR +R K +A L
Sbjct: 1115 KAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSCLKNTEALL 1163
Score = 30.0 bits (66), Expect = 0.94
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 29 QKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
Q K + E + +AA IQA WRG +R+ L+ + A IQ WR
Sbjct: 89 QAFKNILVDEMDMMHARAATLIQANWRGYWLRQKLISQMMAAKAIQEAWR 138
Score = 27.7 bits (60), Expect = 4.6
Identities = 12/43 (27%), Positives = 25/43 (58%)
Query: 99 RERAVIKLQSLVRMWRVRWRYCQVLNAIYIIQGHWQCHNCQTC 141
+++A +QS R +++R + Q A I+Q W+ H+ ++C
Sbjct: 1113 QDKAATAIQSAWRGFKIRQQMRQQQMAAKIVQATWRGHHTRSC 1155
Score = 27.3 bits (59), Expect = 6.1
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 42 IRTKAAVKIQAWWRGTLVRRTLLHAALRAWIIQCWWR 78
IR A + IQA RG L RR + A +IQ WR
Sbjct: 925 IRILAVITIQAGVRGYLARRRIRLWHRGAMVIQATWR 961
>gi|122937315 leucine-rich repeats and IQ motif containing 4 [Homo
sapiens]
Length = 560
Score = 34.7 bits (78), Expect = 0.038
Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 9/37 (24%)
Query: 25 WKTLQKKKQQKIKEKLRIRTKAAVKIQAWWRGTLVRR 61
WK L++ + + I A KIQAWWRGT+V+R
Sbjct: 495 WKYLKENRNRNIM---------ATKIQAWWRGTMVQR 522
>gi|120953300 leucine-rich repeats and IQ motif containing 1 isoform 1
[Homo sapiens]
Length = 1722
Score = 32.7 bits (73), Expect = 0.14
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 8/87 (9%)
Query: 46 AAVKIQAWWRGTLVRR-----TLLHAALRAWIIQCWWRMTLSRVLEK-KRQAALIAYATR 99
AAV IQ++WRG L+RR T LH A + + +L+K KR+ + R
Sbjct: 1338 AAVVIQSYWRGYLMRRQTHFSTRLHTAATEGLPNS--SIKNQTILKKGKRENIVNIRKQR 1395
Query: 100 ERAVIKLQSLVRMWRVRWRYCQVLNAI 126
E+A I +Q++ + + +R + L AI
Sbjct: 1396 EKAAILIQAVWKGFILRKKLTTALEAI 1422
Score = 32.3 bits (72), Expect = 0.19
Identities = 19/46 (41%), Positives = 30/46 (65%), Gaps = 1/46 (2%)
Query: 22 SIEWKTLQKK-KQQKIKEKLRIRTKAAVKIQAWWRGTLVRRTLLHA 66
SI+ +T+ KK K++ I + R KAA+ IQA W+G ++R+ L A
Sbjct: 1373 SIKNQTILKKGKRENIVNIRKQREKAAILIQAVWKGFILRKKLTTA 1418
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.135 0.453
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,496,539
Number of Sequences: 37866
Number of extensions: 193719
Number of successful extensions: 1233
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1073
Number of HSP's gapped (non-prelim): 129
length of query: 164
length of database: 18,247,518
effective HSP length: 94
effective length of query: 70
effective length of database: 14,688,114
effective search space: 1028167980
effective search space used: 1028167980
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.