Guide to the Human Genome
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Name: IQGAP2 Sequence: fasta or formatted (1575aa) NCBI GI: 116089337
Description:

IQ motif containing GTPase activating protein 2

Referenced in:

Additional Interaction Domain Families

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6        104           3
 C cysteine            0.6         10           1
 D aspartate           5.9         93           2
 E glutamate           9.3        147           3
 F phenylalanine       2.4         38           2
 G glycine             3.5         55           2
 H histidine           1.6         25           1
 I isoleucine          6.5        103           2
 K lysine              8.4        132           4
 L leucine            11.4        179           3
 M methionine          2.0         32           1
 N asparagine          6.3        100           2
 P proline             3.2         51           2
 Q glutamine           5.2         82           2
 R arginine            4.5         71           3
 S serine              6.0         94           2
 T threonine           4.9         77           2
 V valine              6.6        104           2
 W tryptophan          0.8         13           1
 Y tyrosine            4.1         65           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   IQ motif containing GTPase activating protein 2 [Ho... 
IQGAP1                0.584   IQ motif containing GTPase activating protein 1 [Homo...
IQGAP3                0.394   IQ motif containing GTPase activating protein 3 [Hom...
NF1                   0.017   neurofibromin isoform 2 
NF1                   0.014   neurofibromin isoform 1 
RASAL2                0.011   RAS protein activator like 2 isoform 1 
SYNGAP1               0.010   synaptic Ras GTPase activating protein 1 
RASA1                 0.010   RAS p21 protein activator 1 isoform 1 
RASA1                 0.010   RAS p21 protein activator 1 isoform 2 
DAB2IP                0.009   disabled homolog 2 interacting protein isoform 2 [Ho...
DAB2IP                0.009   disabled homolog 2 interacting protein isoform 1 [Ho...
TRIP11                0.009   thyroid hormone receptor interactor 11 
GAPVD1                0.008   GTPase activating protein and VPS9 domains 1 
RASAL2                0.008   RAS protein activator like 2 isoform 2 
RASAL1                0.008   RAS protein activator like 1 
HMMR                  0.008   hyaluronan-mediated motility receptor isoform d [Ho...
HMMR                  0.008   hyaluronan-mediated motility receptor isoform a [Ho...
HMMR                  0.008   hyaluronan-mediated motility receptor isoform c [Ho...
HMMR                  0.008   hyaluronan-mediated motility receptor isoform b [Ho...
DCTN1                 0.007   dynactin 1 isoform 4 
DCTN1                 0.007   dynactin 1 isoform 3 
DCTN1                 0.007   dynactin 1 isoform 2 
DCTN1                 0.007   dynactin 1 isoform 1 
ASPM                  0.007   asp (abnormal spindle)-like, microcephaly associate...
LEKR1                 0.006   leucine, glutamate and lysine rich 1 
NES                   0.005   nestin 
MYH15                 0.005   myosin, heavy polypeptide 15 
RASAL3                0.005   RAS protein activator like 3 
GCC2                  0.005   GRIP and coiled-coil domain-containing 2 
GOLGA4                0.005   golgi autoantigen, golgin subfamily a, 4 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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