Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 42544179

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
[Homo sapiens]
         (898 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1 ...  1819   0.0  
gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1 [...  1819   0.0  
gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3 ...  1629   0.0  
gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2 ...  1616   0.0  
gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4 ...  1554   0.0  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    89   1e-17
gi|38788274 bromodomain PHD finger transcription factor isoform ...    89   1e-17
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       89   2e-17
gi|221139761 zinc finger protein 853 [Homo sapiens]                    85   3e-16
gi|148612879 polyhomeotic like 3 [Homo sapiens]                        83   1e-15
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              82   3e-15
gi|148277037 AP2 associated kinase 1 [Homo sapiens]                    81   4e-15
gi|91208418 transcription elongation regulator 1 isoform 2 [Homo...    81   4e-15
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       78   4e-14
gi|33286444 mastermind-like 2 [Homo sapiens]                           74   5e-13
gi|38788260 bromodomain PHD finger transcription factor isoform ...    74   8e-13
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    73   1e-12
gi|110349719 titin isoform N2-A [Homo sapiens]                         72   2e-12
gi|146134388 YLP motif containing 1 [Homo sapiens]                     72   3e-12
gi|50345997 E1A binding protein p300 [Homo sapiens]                    71   4e-12
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              71   4e-12
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    71   5e-12
gi|56549696 E1A binding protein p400 [Homo sapiens]                    71   5e-12
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   70   7e-12
gi|21327715 transcription elongation regulator 1 isoform 1 [Homo...    70   9e-12
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 68   3e-11
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s...    68   3e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          68   4e-11
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          68   4e-11
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          68   4e-11

>gi|196115147 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1819 bits (4711), Expect = 0.0
 Identities = 898/898 (100%), Positives = 898/898 (100%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
           VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
           LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|42544179 CDKN1A interacting zinc finger protein 1 isoform 1
           [Homo sapiens]
          Length = 898

 Score = 1819 bits (4711), Expect = 0.0
 Identities = 898/898 (100%), Positives = 898/898 (100%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360

Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
           VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ
Sbjct: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420

Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
           LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480

Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540

Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600

Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660

Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720

Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780

Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840

Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898


>gi|196115153 CDKN1A interacting zinc finger protein 1 isoform 3
           [Homo sapiens]
          Length = 837

 Score = 1629 bits (4219), Expect = 0.0
 Identities = 826/898 (91%), Positives = 827/898 (92%), Gaps = 61/898 (6%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
           PQKQARTSSSTTPNRK     TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRK-----TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 235

Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 236 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 295

Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
           EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ
Sbjct: 296 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 355

Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
           VQPQLQQEAEPQKQVQPQV  QA                    QP VQPQ H  PP QV 
Sbjct: 356 VQPQLQQEAEPQKQVQPQVHTQA--------------------QPSVQPQEH--PPAQVS 393

Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
           +Q                          PP Q   QP        HTQPQVSLLAPEQTP
Sbjct: 394 VQ--------------------------PPEQTHEQP--------HTQPQVSLLAPEQTP 419

Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 420 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 479

Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 480 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 539

Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 540 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 599

Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 600 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 659

Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 660 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 719

Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 720 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 779

Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 780 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 837


>gi|196115141 CDKN1A interacting zinc finger protein 1 isoform 2
           [Homo sapiens]
          Length = 842

 Score = 1616 bits (4184), Expect = 0.0
 Identities = 819/898 (91%), Positives = 830/898 (92%), Gaps = 56/898 (6%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180

Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240

Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300

Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
           EALEAQVLPRFQPRVLQVQAQVQS           Q QP++     T T          Q
Sbjct: 301 EALEAQVLPRFQPRVLQVQAQVQS-----------QTQPRIPS---TDT----------Q 336

Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
           VQP+LQ++A+ Q               P  + LQQ     KQVQPQ+Q +A  +P +QVQ
Sbjct: 337 VQPKLQKQAQTQTS-------------PEHLVLQQ-----KQVQPQLQQEA--EPQKQVQ 376

Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
                       PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 377 ------------PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 424

Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 425 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 484

Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 485 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 544

Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 545 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 604

Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 605 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 664

Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 665 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 724

Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 725 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 784

Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 785 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 842


>gi|196115158 CDKN1A interacting zinc finger protein 1 isoform 4
           [Homo sapiens]
          Length = 818

 Score = 1554 bits (4023), Expect = 0.0
 Identities = 795/898 (88%), Positives = 806/898 (89%), Gaps = 80/898 (8%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP
Sbjct: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
           PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG                        
Sbjct: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG------------------------ 96

Query: 121 NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
           NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN
Sbjct: 97  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 156

Query: 181 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
           PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK
Sbjct: 157 PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 216

Query: 241 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 300
           EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP
Sbjct: 217 EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP 276

Query: 301 EALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
           EALEAQVLPRFQPRVLQVQAQVQS           Q QP++     T T          Q
Sbjct: 277 EALEAQVLPRFQPRVLQVQAQVQS-----------QTQPRIPS---TDT----------Q 312

Query: 361 VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQ 420
           VQP+LQ++A+ Q               P  + LQQ     KQVQPQ+Q +A  +P +QVQ
Sbjct: 313 VQPKLQKQAQTQTS-------------PEHLVLQQ-----KQVQPQLQQEA--EPQKQVQ 352

Query: 421 LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 480
                       PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP
Sbjct: 353 ------------PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTP 400

Query: 481 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
           VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG
Sbjct: 401 VVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 460

Query: 541 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 600
           VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA
Sbjct: 461 VWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKA 520

Query: 601 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 660
           SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ
Sbjct: 521 SCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETEDEEPPPRRWCNTCQ 580

Query: 661 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 720
           LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE
Sbjct: 581 LYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLE 640

Query: 721 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 780
           KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE
Sbjct: 641 KEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEELCKQVRSRDISREEWKGSE 700

Query: 781 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 840
           TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT
Sbjct: 701 TYSPNTAYGVDFLVPVMGYICRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAKNPSPT 760

Query: 841 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 898
           TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT
Sbjct: 761 TRPVSRRCAINARNALTALFTSSGRPPSQPNTQDKTPSKVTARPSQPPLPRRSTRLKT 818


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 161/602 (26%), Positives = 217/602 (36%), Gaps = 87/602 (14%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQL-QQQQLQQQQL--LQLQQLLQQSPPQAPLPMAVSRGLP 60
            Q QQQQ  QQQQQLQQ QQQQL QQQQLQQQQL   Q QQ LQQ   Q            
Sbjct: 3899 QLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQ 3958

Query: 61   PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLG 120
             QQ QQ     Q      LLN S   R LL  Q Q   Q A+ P         MP   L 
Sbjct: 3959 QQQQQQQFQQQQQQQQMGLLNQS---RTLLSPQQQQQQQVALGPG--------MPAKPLQ 4007

Query: 121  NLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP-VGVPMNPSQFNLSGR 179
            +      +SPG   P+L    L         P  + ++  GP    G P+        G 
Sbjct: 4008 H-----FSSPGALGPTLL---LTGKEQNTVDPAVSSEATEGPSTHQGGPL------AIGT 4053

Query: 180  NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
             P+  A       P+     SQ + V+ +  P   S +   P     + Q          
Sbjct: 4054 TPESMATEPGEVKPS-LSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112

Query: 240  KEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK----AQPQARMTVPKQT-- 293
                         EAS +P   L +    +  + PG +        QP     +   T  
Sbjct: 4113 GGSHGQLGSGSSSEASSVP--HLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGP 4170

Query: 294  QTPDLLPEALEAQVLP--RFQPRVLQVQAQVQS------QTQPRIPSTDTQVQPKL-QKQ 344
            Q P   P     Q LP     P V Q++AQ+Q       Q +   P    Q+Q  L Q+Q
Sbjct: 4171 QPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230

Query: 345  AQ---------------TQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPR 389
             Q               TQTSP   +L     QPQL     PQ     ++      QGP 
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLL---GCQPQLGGFPGPQTGPLQELGAGPRPQGPP 4287

Query: 390  QVQLQQEA----EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ-PSVQ 444
            ++     A      L  V P   P +  +P R  QL            Q+ T+AQ P   
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS-------QLPTEAQLPPTH 4340

Query: 445  PQEHPPAQVSVQPPEQTHEQPHTQPQVSL----LAPEQTPVVVHVCGLEMPPDAVEAGGG 500
            P    P   +++PP         Q   +L    L P   P   ++   + P  +    G 
Sbjct: 4341 PGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP--DNLAETQKPEQSSLVPGH 4398

Query: 501  MEKTLPE--PVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDS 558
            +++   +  P  +Q+S+++   E  C L     +  A   P   GA G+    +L    S
Sbjct: 4399 LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEP--IGAPGTSNHLLLAGPRS 4456

Query: 559  RA 560
             A
Sbjct: 4457 EA 4458



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 138/536 (25%), Positives = 198/536 (36%), Gaps = 76/536 (14%)

Query: 4    QQQQQQLQQQQQQ----LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAP-----LPMA 54
            Q+Q  Q+++QQ++    + + + +Q QQQQ QQQQ  Q   +L  SP Q+P     LP  
Sbjct: 3575 QKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQ 3634

Query: 55   VSRGLPPQQPQQP--------LLNLQGTNSASLLNGSMLQRALLLQQLQ----GLDQFAM 102
            +  G   Q PQ P         L   G        G  L  AL  QQ Q    G    A 
Sbjct: 3635 LLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAG 3694

Query: 103  PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ----LATPNLQQFFPQATRQS 158
            P   +    L         LR  G  S  L    L   Q    LA    QQ   Q  +Q 
Sbjct: 3695 PSGGFFPGNLA--------LRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQH 3746

Query: 159  LLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKS-DPPEGSEE 217
            LLG   +       Q    G   Q               SS Q + V+  S  PP+G + 
Sbjct: 3747 LLGQVAI------QQQQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQG 3800

Query: 218  AAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQL 277
                         L P    + +++   A  P+       P +++  ++      P    
Sbjct: 3801 M------------LGPAQVAVLQQQHPGALGPQG------PHRQVLMTQSRVLSSPQLAQ 3842

Query: 278  QVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQV 337
            Q +     R+   +Q Q      +      L   Q  ++    Q +   QP       Q 
Sbjct: 3843 QGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQ 3902

Query: 338  QPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEA 397
            Q +LQ+Q Q Q   +    QQ Q Q QLQQ+   Q+Q Q Q+Q Q      +Q QLQQ+ 
Sbjct: 3903 QQQLQQQQQLQQQQQ----QQLQQQQQLQQQQLQQQQQQQQLQQQ------QQQQLQQQQ 3952

Query: 398  EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQP 457
            + L+Q Q Q Q Q   Q  +Q Q+ L  Q +T   PQ   Q Q ++ P       +  +P
Sbjct: 3953 QQLQQ-QQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGP------GMPAKP 4005

Query: 458  PEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGME-KTLPEPVGTQ 512
             +         P + L   EQ  V   V        +   GG +   T PE + T+
Sbjct: 4006 LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATE 4061



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 99/389 (25%), Positives = 147/389 (37%), Gaps = 47/389 (12%)

Query: 130 PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSS 189
           P      L+PP   +P      P+A+R   L PPP   PM+P         P + +R S 
Sbjct: 601 PPFEESPLSPPPEESPLSPP--PEASR---LSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655

Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEP 249
               +R     +  P+   S PPE S     P    PE   L P PED        +P P
Sbjct: 656 LPVVSRLSPPPEESPL---SPPPEES-----PTSPPPEASRLSPPPED-----SPTSPPP 702

Query: 250 EPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP 309
           E   AS  P   L S   P E+ P   L +  +PQ    +  +++ P L P   E  + P
Sbjct: 703 EDSPASPPPEDSLMSL--PLEESP--LLPLPEEPQ----LCPRSEGPHLSPRPEEPHLSP 754

Query: 310 RFQPRVLQVQA-QVQSQTQPRIPS-TDTQVQPKLQKQAQ---TQTSPEHLVLQQKQVQPQ 364
           R +   L  QA +     QP  P       +P L  QA+       PE L L  +  +P 
Sbjct: 755 RPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814

Query: 365 LQQEAE-----PQKQ---VQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPP 416
           L    E     PQ +   + PQ +    S  P +  L  E E     +P + P+    P 
Sbjct: 815 LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE-----KPPLSPRPEKPPE 869

Query: 417 RQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQP-PEQTHEQPHTQPQVS--L 473
              Q    +++     P   + +    +P    P +  + P PE+    P  +P +S  L
Sbjct: 870 EPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929

Query: 474 LAPEQTPVVVHVCGLEMPPDAVEAGGGME 502
           + P+  P  +        P A+   G +E
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELE 958



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 131/532 (24%), Positives = 194/532 (36%), Gaps = 148/532 (27%)

Query: 4    QQQQQQLQQQQQQL-QQLQQQQLQQQQLQQQQLL---QLQQLLQQSP-----------PQ 48
            Q++Q QLQQQ+ QL Q+LQQQ  QQQQ QQQ LL    +QQ  QQ P           PQ
Sbjct: 3717 QERQLQLQQQRMQLAQKLQQQ--QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQ 3774

Query: 49   APLPMAVSRG-----LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP 103
              +P +  +G     L PQ PQ P    QG    +       Q A+L QQ  G       
Sbjct: 3775 GLMPPSSHQGLLVQQLSPQPPQGP----QGMLGPA-------QVAVLQQQHPG------- 3816

Query: 104  PATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLG 161
                   G   P   +   +   ++SP LA     L   +L T   QQ   Q  +Q    
Sbjct: 3817 -----ALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQG--- 3868

Query: 162  PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 221
                         +++G +  +Q+  S S  P               S  P GS +  + 
Sbjct: 3869 -------------SMAGLSHLQQSLMSHSGQPK-------------LSAQPMGSLQQLQQ 3902

Query: 222  RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
            +    + Q L    +   ++++            +L  ++L+  ++  + +   Q Q++ 
Sbjct: 3903 QQQLQQQQQLQQQQQQQLQQQQ------------QLQQQQLQQQQQQQQLQQQQQQQLQQ 3950

Query: 282  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
            Q Q                     Q+  + Q +  Q Q Q Q Q    +  + T + P+ 
Sbjct: 3951 QQQ---------------------QLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQ 3989

Query: 342  QKQAQTQTSPEHLVLQQKQVQ---------PQLQQEAEPQKQVQPQVQ------PQAHSQ 386
            Q+Q Q    P    +  K +Q         P L    + Q  V P V       P  H  
Sbjct: 3990 QQQQQVALGPG---MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQG 4046

Query: 387  GPRQVQLQQEA---EP------------LKQVQPQVQPQAHS---QPPRQVQLQLQKQVQ 428
            GP  +    E+   EP            L  VQPQ QPQ  S   QPP ++  Q Q+QV 
Sbjct: 4047 GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVS 4106

Query: 429  T--QTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 478
                     H Q       +      +  QP     +QP +  Q +LL P+Q
Sbjct: 4107 LLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ-NLLGPQQ 4157



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 99/419 (23%), Positives = 153/419 (36%), Gaps = 52/419 (12%)

Query: 137 LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS---SSTTP 193
           L+PP   +P      P+A+R   L PPP  +P +P    L    P +++  S     +  
Sbjct: 449 LSPPPEESPTSPP--PEASR---LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPL 503

Query: 194 NRKDSSSQTMPVEDKS-DPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
           +    SS   P+E+    PPE  E    P ++TP        P     E+   +P PE  
Sbjct: 504 SPPPESSPFSPLEESPLSPPE--ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEEL 561

Query: 253 EASELP-AKRLR-SSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP- 309
             S  P A RL    EE     PP +  +   P+A    P   ++P L P   E+ + P 
Sbjct: 562 PTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESP-LSPPPEESPLSPP 620

Query: 310 ----RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ--- 362
               R  P           +  P  P  +      L   ++    PE   L     +   
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680

Query: 363 ---PQLQQEAEPQKQVQPQVQPQAHSQGP----RQVQLQQEAEPLKQV--QPQVQPQAHS 413
              P+  + + P +       P+     P      + L  E  PL  +  +PQ+ P++  
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740

Query: 414 Q--PPRQVQLQLQKQVQTQTYPQVHTQA-QPSVQPQEHPPAQVSVQPPEQTH-----EQP 465
               PR  +  L  + +    P +  QA +P + PQ   P   +V  PE+ H     E P
Sbjct: 741 PHLSPRPEEPHLSPRPEE---PHLSPQAEEPHLSPQPEEPCLCAV--PEEPHLSPQAEGP 795

Query: 466 HTQPQVSLL-------APEQTPVVVHVCGLEMPPDAVEAGGGMEKTL-PEPVGTQVSME 516
           H  PQ   L        P  +PV    C    P ++  +    E  L P P  + +S E
Sbjct: 796 HLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 98/443 (22%), Positives = 166/443 (37%), Gaps = 80/443 (18%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
            + ++++LQ++QQ   QLQ  Q QQQQ QQ  LL         P QA              
Sbjct: 3254 EHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLS-----APGPAQA-------------- 3294

Query: 64   PQQPLLNLQGTNSASLLNGSMLQRALLL--QQLQGLDQFAMP--PATYDTAGLTMPTATL 119
                 ++L    S+  L GS  Q +L L   +  GL Q  MP  P  +       P+  +
Sbjct: 3295 -----MSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLAPSMAM 3349

Query: 120  GNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR 179
             + +G+ ++        L P Q + P L         Q  +G  P  + M P Q  +   
Sbjct: 3350 VSNQGHMLSGQHGGQAGLVPQQSSQPVLS--------QKPMGTMPPSMCMKPQQLAM--- 3398

Query: 180  NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCP--- 235
                Q + ++S  P   D+       ED  DP   ++  A   +     Q  +   P   
Sbjct: 3399 ----QQQLANSFFP---DTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMN 3451

Query: 236  ---EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP------PGQLQVKAQPQAR 286
                 +  ++ +  P  +        + + RS+ +P++  P       G +    Q Q  
Sbjct: 3452 RQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYE 3511

Query: 287  MTVPKQTQTPDLLPEALEAQV-LPRFQPRVLQVQAQVQSQTQPRIPSTD-------TQVQ 338
              +    Q   +  + LE Q+ + R   + L  + +   +     P  D       T+ Q
Sbjct: 3512 EWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQ 3571

Query: 339  PKLQKQ----AQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQ 394
             K+QKQ     + Q    +L+ + +  Q Q QQ+ + Q+Q    V   + SQ PR     
Sbjct: 3572 SKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRL---- 3627

Query: 395  QEAEPLKQVQPQVQPQAHSQPPR 417
                 L ++  Q+ P    QPP+
Sbjct: 3628 -----LTKLPGQLLPGHGLQPPQ 3645



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 96/470 (20%), Positives = 157/470 (33%), Gaps = 96/470 (20%)

Query: 132  LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS--- 188
            ++ P    P    P + +  P     S L PPP   P++P         P + +R S   
Sbjct: 635  MSPPPEESPMSPPPEVSRLSPLPV-VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP 693

Query: 189  --SSTTPNRKDS--------SSQTMPVEDKSDPPEGSEEAAEPRMD------TPEDQDLP 232
              S T+P  +DS        S  ++P+E+    P   E    PR +       PE+  L 
Sbjct: 694  EDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLS 753

Query: 233  PCPED--IAKEKRTPAPEPEP-----CEASELP-----AKRLRSSEEPTE-------KEP 273
            P PE+  ++ +   P   P+P     C   E P     A+    S +P E       +EP
Sbjct: 754  PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813

Query: 274  -----PGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQP 328
                 P +  +  QP+     P Q++ P L P   E+ + P  +   L  + +   +   
Sbjct: 814  HLSPVPEEPCLSPQPEESHLSP-QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG 872

Query: 329  RIPSTDT----------QVQPKLQKQAQTQTS-------PEHLVLQQKQVQPQLQQEAEP 371
            + P+ +            + P L + A ++         PE L L     +P L  +  P
Sbjct: 873  QCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-EPSLSPQLMP 931

Query: 372  QKQVQPQVQPQAHSQGPRQVQLQQEAE-----------------PLKQVQPQVQPQAHSQ 414
               + P + P   +  P  +    E E                 P+ +      P+A+  
Sbjct: 932  PDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT 991

Query: 415  PPRQVQLQLQKQ------------VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTH 462
             P  V   +               +     PQ     Q S+ PQ  PP+Q S  PP    
Sbjct: 992  DPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS--PPALPL 1049

Query: 463  EQPHTQPQVSLLAPEQTPVVVHVCGLE--MPPDAVEAGGGMEKTLPEPVG 510
              P     +  +        +H    E    P+           LP P+G
Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMG 1099



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 84/395 (21%), Positives = 127/395 (32%), Gaps = 65/395 (16%)

Query: 103  PPATYDTAGLTMPTATLG---NLRGY---------GMASPG---LAAPSLTPPQLATPN- 146
            PPA   T  +  PT   G   +  G+         G  SPG   L  P   P Q+ + + 
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176

Query: 147  --------LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDS 198
                    L+  FP A       P P G P  P     S R    Q     +T P     
Sbjct: 2177 FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG---- 2232

Query: 199  SSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE-- 256
                 P    S P    +   +PR  + ++  +P  P     +   P   P P   S   
Sbjct: 2233 ----TPRHQPSTP----DPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284

Query: 257  LPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
            L  K+           PP    V +          + +TPD+     +A + PR      
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDV----FKAPLTPR------ 2334

Query: 317  QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 376
                   SQ +P+ P    + Q     QA   + P H  +     +P    +   Q  + 
Sbjct: 2335 ------ASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI----FRPGSYTDPYAQPPLT 2384

Query: 377  PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQV 435
            P+ QP               ++P  +V    Q Q+ SQ P        + +  + + P  
Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSP-----LTPRPLSAEAFCPSP 2439

Query: 436  HTQAQPSVQPQEHPPAQVSVQPP-EQTHEQPHTQP 469
             T    S  P   PP++   + P    H+ P  QP
Sbjct: 2440 VTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQP 2474



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 82/385 (21%), Positives = 135/385 (35%), Gaps = 57/385 (14%)

Query: 129  SPGLAAPSLTPPQLATPNLQQFFP--QATRQSL------LGPPPVGVPMNPSQ-FNLSGR 179
            SPG+     + P L+ P   +     +  ++ L       GPP +G   +PS   +L G 
Sbjct: 2260 SPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGL 2319

Query: 180  NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
              +      +  TP       Q+  +  +   P  ++  A      P+        +  A
Sbjct: 2320 ELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYA 2379

Query: 240  KEKRTPAPEPEPCEAS-ELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL 298
            +   TP P+P P E+   LP + L S  +P  + P       A PQ++ +    +Q+P  
Sbjct: 2380 QPPLTPRPQPPPPESCCALPPRSLPS--DPFSRVP-------ASPQSQSS----SQSP-- 2424

Query: 299  LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
                          PR L  +A   S   PR  S D   +P  + Q++   +P H   + 
Sbjct: 2425 ------------LTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRP 2472

Query: 359  KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
            +  +   +  +     +     P A   GP        A  L    P  QP    + P  
Sbjct: 2473 QPPEVAFKAGSLAHTSLGAGGFPAALPAGP--------AGELHAKVPSGQPPNFVRSPGT 2524

Query: 419  VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQ 478
                        T+PQ     +PS++P   P  Q  + PP   +   H  P  +L  P+ 
Sbjct: 2525 GAFVGTPSPMRFTFPQ--AVGEPSLKP---PVPQPGLPPPHGINS--HFGPGPTLGKPQS 2577

Query: 479  TPVVV-----HVCGLEMPPDAVEAG 498
            T   V     H  G  + P +   G
Sbjct: 2578 TNYTVATGNFHPSGSPLGPSSGSTG 2602



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 44/185 (23%), Positives = 71/185 (38%), Gaps = 8/185 (4%)

Query: 315 VLQVQAQVQSQTQPRIPS-TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
           V +    V S+  P  P  T T     L    Q Q    H+   Q +    LQ EA+P  
Sbjct: 361 VAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLG 420

Query: 374 QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ-LQKQVQTQTY 432
           +   Q++PQ  +    ++ L    E    + P  +    S PP   +L    +++     
Sbjct: 421 KAGVQLEPQLEAPLNEEMPLLPPPEE-SPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479

Query: 433 PQ-VHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAP--EQTPVVVHVCGLE 489
           P+ +H        P   PP +  + PP ++   P +  + S L+P  E  P       L 
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPES--SPFSPLEESPLSPPEESPPSPALETPLS 537

Query: 490 MPPDA 494
            PP+A
Sbjct: 538 PPPEA 542


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 105/375 (28%), Positives = 155/375 (41%), Gaps = 57/375 (15%)

Query: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
            Q T Q  L P  V V   P Q  +    P    Q+   T  +TT     +++ T+     
Sbjct: 2174 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2232

Query: 209  SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
            +   E  +    P+M   +D+ LPP                 P EA    A+     +  
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2282

Query: 269  TEKEPPGQLQVKAQPQARMTVPKQTQTPDLLP----EALEAQVLPRFQPRVLQVQAQ--- 321
            T+ + P Q +V+ QP+ +      +  P        ++ + QV  + QP+   VQ Q   
Sbjct: 2283 TQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQS-NVQGQSPV 2341

Query: 322  -VQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPE-----HLVLQ-----QKQVQPQLQQEA 369
             VQS +Q RI PST +Q+ P  Q Q QT TS       H  LQ     Q Q QPQ+Q   
Sbjct: 2342 RVQSPSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSST 2401

Query: 370  EP--------QKQVQPQVQPQAHSQGPR-QV----QLQQEAEPLKQVQPQVQPQAHSQP- 415
            +         Q  V    +PQ   Q P+ QV    QLQQ+ + L Q+Q QV  Q  +Q  
Sbjct: 2402 QTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQAQQS 2461

Query: 416  --PRQVQLQL------QKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 467
              P+Q++LQL         VQT     V T    SVQ Q     Q+  Q  ++  +Q   
Sbjct: 2462 GVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQQQIEI 2521

Query: 468  QPQVSLLAPEQTPVV 482
            + + +L A  Q+ ++
Sbjct: 2522 KREHTLQASNQSEII 2536



 Score = 77.4 bits (189), Expect = 6e-14
 Identities = 78/272 (28%), Positives = 115/272 (42%), Gaps = 54/272 (19%)

Query: 282  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2238 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2292

Query: 341  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
            +Q Q + QT          + QP   Q ++PQ  V  Q QPQ++ QG   V++Q  +   
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ--VAAQSQPQSNVQGQSPVRVQSPS--- 2347

Query: 401  KQVQPQVQPQAHSQ--PPRQVQLQLQKQ----VQTQTYPQVHTQAQPSVQPQ-------- 446
               Q +++P   SQ  P +Q Q+Q        +Q  T  Q+ +Q QP  QPQ        
Sbjct: 2348 ---QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQSSTQTL 2404

Query: 447  --------------EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 492
                            P  Q+  QP  Q    P  Q QV +L+  Q+ VV  +       
Sbjct: 2405 SSGQTLNQVTVSSPSRPQLQIQ-QPQPQVIAVPQLQQQVQVLSQIQSQVVAQI------- 2456

Query: 493  DAVEAGGGMEKTLPEPVGTQ----VSMEEIQN 520
             A ++G   +  L  P+  Q    V   +IQN
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQN 2488



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 62/221 (28%), Positives = 84/221 (38%), Gaps = 15/221 (6%)

Query: 275  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 2177 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2232

Query: 335  T----QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
                 Q Q KL  Q Q          Q   V P   Q    Q   QPQ Q Q  S    +
Sbjct: 2233 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPE 2292

Query: 391  VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
            VQ Q E +    V   V  +A    P   Q   + QV  Q+ PQ + Q Q  V+ Q   P
Sbjct: 2293 VQTQPEVQTQTTVSSHVPSEAQ---PTHAQ-SSKPQVAAQSQPQSNVQGQSPVRVQS--P 2346

Query: 451  AQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
            +Q  ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2347 SQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2386



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 16/102 (15%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQLQQQ-----QLQQQQLLQLQQLLQQSPPQAPLPMAVSR 57
            S   + QLQ QQ Q Q +   QLQQQ     Q+Q Q + Q+Q        Q+ +P  +  
Sbjct: 2416 SSPSRPQLQIQQPQPQVIAVPQLQQQVQVLSQIQSQVVAQIQ------AQQSGVPQQIKL 2469

Query: 58   GLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQ 99
             LP Q  Q          +  + N   +Q A + +QLQ + Q
Sbjct: 2470 QLPIQIQQS-----SAVQTHQIQNVVTVQAASVQEQLQRVQQ 2506



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 95/475 (20%), Positives = 150/475 (31%), Gaps = 73/475 (15%)

Query: 164  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 1844 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 1899

Query: 224  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 1900 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 1959

Query: 283  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 1960 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2019

Query: 333  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 2020 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2079

Query: 375  ----VQPQVQPQAHSQ------------GPRQVQLQQEAEPLKQVQPQVQPQAH-SQPPR 417
                VQP    Q  +Q             P  V      + L         Q+  SQPPR
Sbjct: 2080 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR 2139

Query: 418  QVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLL 474
              Q Q++            T AQ +   Q H   Q   V +Q   QT  Q    PQ   +
Sbjct: 2140 PQQGQVKL-----------TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTV 2188

Query: 475  APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENR 534
             P     ++          A    G +++ L  P+ T  +       +      G  E R
Sbjct: 2189 LPGPGQQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQR 2239

Query: 535  AREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQ 589
              ++           +   QSS        P T  P       + P + + P  Q
Sbjct: 2240 QSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQ 2294



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 709 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 761
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 91/324 (28%), Positives = 133/324 (41%), Gaps = 51/324 (15%)

Query: 5   QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
           Q QQQ+QQQQQQLQ++       QQQQ QQQQ QQQQ LQ Q  +QQ P   PQ P   A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285

Query: 55  VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
           + + L          PP QPQQP +     N  S L      + L+   Q L G   +  
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL--- 159
           PP  +  A + +    +       +     A  +    Q+  P +Q       +  +   
Sbjct: 343 PPLKFVRAPMVVQQPPVQP----QVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIR 398

Query: 160 -LGPPPVGVPMNPSQFNLSGRNPQKQARTS-----SSTTPNRKDSSSQTMPVEDKSDPPE 213
              PP   V   PS     GR P  Q   S     SS +P ++  + Q+MP      PP+
Sbjct: 399 ARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMP-----PPPQ 453

Query: 214 GSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP 273
            S +  +P      +    P P   +     P+P P+P + S + A+  ++   P+    
Sbjct: 454 PSPQPGQPSSQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS---- 505

Query: 274 PGQLQVKAQPQARMTVPKQTQTPD 297
           PG L     P + M+    +Q  +
Sbjct: 506 PGPLNTPVNPSSVMSPAGSSQAEE 529



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 65/197 (32%), Positives = 90/197 (45%), Gaps = 17/197 (8%)

Query: 276 QLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDT 335
           Q Q++ Q  A     +Q Q       AL+ Q   + Q +    Q+ +Q Q Q  +     
Sbjct: 150 QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVV----- 204

Query: 336 QVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ 395
           Q Q +LQ+Q Q Q   +HL+    Q Q Q+QQ+   Q+Q+Q   Q Q   Q  +Q Q QQ
Sbjct: 205 QQQQQLQQQQQQQ---QHLIKLHHQNQQQIQQQ---QQQLQRIAQLQLQQQQQQQQQQQQ 258

Query: 396 EAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV 455
           + +   Q QP +Q     QP       L +Q+Q   + Q H   QP  QPQ+ P AQ   
Sbjct: 259 QQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHH---QPPPQPQQPPVAQ--- 312

Query: 456 QPPEQTHEQPHTQPQVS 472
             P Q   Q  TQP VS
Sbjct: 313 NQPSQLPPQSQTQPLVS 329



 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 83/282 (29%), Positives = 120/282 (42%), Gaps = 23/282 (8%)

Query: 246 APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
           AP      ++  P  +L+  +   +++   Q Q + Q QA +   +Q Q      +A ++
Sbjct: 137 APHSMAVVSTATPQTQLQLQQVALQQQQQQQ-QFQQQQQAALQQQQQQQQQQQF-QAQQS 194

Query: 306 QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQ 364
            +  +FQ  V Q Q  Q Q Q Q  +     Q Q ++Q+Q Q       L LQQ+Q Q Q
Sbjct: 195 AMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQ 254

Query: 365 LQQEAEPQK-QVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
            QQ+ + Q  Q QP +Q     Q P Q      ++ L Q   Q+    H QPP Q Q   
Sbjct: 255 QQQQQQQQALQAQPPIQ-----QPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPP 309

Query: 424 QKQVQTQTYPQVHTQAQPSV-QPQEHPPAQVSVQPP----------EQTHEQPHTQPQVS 472
             Q Q    P   +Q QP V Q Q  P   +  QPP          +Q   QP  Q Q +
Sbjct: 310 VAQNQPSQLPP-QSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQT 368

Query: 473 LLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVS 514
            +   Q   +V   G++M  +A+ A GGM      P  T VS
Sbjct: 369 AVQTAQAAQMV-APGVQMITEAL-AQGGMHIRARFPPTTAVS 408



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 100/437 (22%), Positives = 148/437 (33%), Gaps = 85/437 (19%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQQQ QQQQQ   Q QQQQ QQQQ Q QQ    QQ       Q  L          QQ
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ-------QQQ 215

Query: 64  PQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLR 123
            QQ L+ L   N   +       + +   QLQ   Q            L           
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQAL----------- 264

Query: 124 GYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQK 183
               A P +  P +  PQ   P   Q  PQ  +Q           M+ +Q +     PQ 
Sbjct: 265 ---QAQPPIQQPPMQQPQ---PPPSQALPQQLQQ-----------MHHTQHHQP--PPQP 305

Query: 184 QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMD---TPEDQDLPPCPEDIAK 240
           Q    +   P++    SQT P+  ++    G     +P +     P     PP    + +
Sbjct: 306 QQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQ 365

Query: 241 EKRTPAPEPEPCEASELPA---------------------------KRLRSSEEPTEKEP 273
           ++       +  +A+++ A                             + SS  P  ++P
Sbjct: 366 QQTA----VQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQP 421

Query: 274 PGQLQVKAQPQARMTVP-KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
             Q+   + P      P +Q QTP  +P   +    P  QP   Q  + V S   P   S
Sbjct: 422 MAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG-QPS-SQPNSNVSSGPAPSPSS 479

Query: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQ 392
                 P+  +   T  +P++  +        L     P   + P         G  Q +
Sbjct: 480 FLPSPSPQPSQSPVTARTPQNFSVPS---PGPLNTPVNPSSVMSP--------AGSSQAE 528

Query: 393 LQQEAEPLKQVQPQVQP 409
            QQ  + LKQ+   ++P
Sbjct: 529 EQQYLDKLKQLSKYIEP 545



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 30/95 (31%), Positives = 38/95 (40%), Gaps = 9/95 (9%)

Query: 378 QVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQV----QTQTYP 433
           Q  P      P  + +   A P  Q Q Q+Q  A  Q  +Q Q Q Q+Q     Q Q   
Sbjct: 128 QPPPGTSGMAPHSMAVVSTATP--QTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQ 185

Query: 434 QVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
           Q   QAQ S   Q+    Q  VQ  +Q  +Q   Q
Sbjct: 186 QQQFQAQQSAMQQQF---QAVVQQQQQLQQQQQQQ 217


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 84.7 bits (208), Expect = 3e-16
 Identities = 91/331 (27%), Positives = 143/331 (43%), Gaps = 30/331 (9%)

Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
           P+     S     +++ +P E +     P +  P          +IA+E R         
Sbjct: 39  PDTLSGGSGGSESQEEEEPQERNSSPQRPAVSAPVGAS------EIAEETRPGQ------ 86

Query: 253 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 312
              EL  ++L    EP ++    QLQ   QPQ  + + +Q       P+    Q L + Q
Sbjct: 87  --RELQLQQLEQQPEPQQQPQHEQLQ---QPQPHLELQQQ-------PQQDGQQQLSQLQ 134

Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEP 371
               Q     + + + ++     Q+QP+ +Q+Q + Q   E L  QQ Q Q  LQQ+ + 
Sbjct: 135 QEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQL 194

Query: 372 QKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQT 431
           Q+QVQ Q   Q   +  +Q QL Q+ E L+Q Q Q Q +   Q  + + LQ Q Q+Q Q 
Sbjct: 195 QQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQL 254

Query: 432 YPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
             Q   QAQ   Q  E   AQ+  Q   Q  EQ   Q Q  LL  +Q  +      L+ P
Sbjct: 255 LQQ--QQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQ--QLQPP 310

Query: 492 PDAVEAGGGME-KTLPEPVGTQVSMEEIQNE 521
           P   E    +E + +P  +G++  +E+ + E
Sbjct: 311 PLEPEEEEEVELELMPVDLGSEQELEQQRQE 341



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 86/323 (26%), Positives = 139/323 (43%), Gaps = 37/323 (11%)

Query: 171 PSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ- 229
           P    LSG +   +++      P  ++SS Q   V   S P   SE A E R    E Q 
Sbjct: 37  PGPDTLSGGSGGSESQEEEE--PQERNSSPQRPAV---SAPVGASEIAEETRPGQRELQL 91

Query: 230 ---DLPPCPEDIAKEKRTPAPEP------EPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
              +  P P+   + ++   P+P      +P +  +    +L+  +  +      + +++
Sbjct: 92  QQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQ 151

Query: 281 AQPQARMTVPKQTQTPDLLPEALEA-QVLPRFQPRVLQVQAQVQSQTQPR--IPSTDTQV 337
              Q +   P+Q Q    L +  E  Q     + +VLQ Q Q+Q Q Q +  +     Q+
Sbjct: 152 LMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQL 211

Query: 338 QPKLQKQAQTQTSPEHLVLQQKQVQPQ-----LQQEAEPQKQVQPQVQPQAHSQ--GPRQ 390
           Q +   Q Q Q   +    QQ+Q+Q Q     LQQ+ + Q+Q+  Q Q Q   Q    +Q
Sbjct: 212 QQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQ 271

Query: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
            QLQQ+   L Q Q Q+Q Q   Q  +Q Q QLQ+Q   Q  P       P ++P+E   
Sbjct: 272 AQLQQQL--LLQQQEQLQQQQQQQLLQQQQEQLQQQ---QLQP-------PPLEPEEEEE 319

Query: 451 AQVSVQPPEQTHEQPHTQPQVSL 473
            ++ + P +   EQ   Q +  L
Sbjct: 320 VELELMPVDLGSEQELEQQRQEL 342



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 61/235 (25%), Positives = 106/235 (45%), Gaps = 21/235 (8%)

Query: 253 EASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQ 312
           +  +L  ++L   +E  +++   Q Q + Q Q ++ + +Q     L  + L+ Q     Q
Sbjct: 207 QQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG--QLQQQLLQQQQAQLQQ 264

Query: 313 PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ 372
             + Q QAQ+Q Q          Q Q +LQ+Q Q Q      +LQQ+Q Q Q QQ   P 
Sbjct: 265 QLLEQQQAQLQQQLL-------LQQQEQLQQQQQQQ------LLQQQQEQLQQQQLQPPP 311

Query: 373 KQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY 432
            + + + + +     P  +  +QE E  +Q   + Q     Q  RQ+QL+LQ+++Q    
Sbjct: 312 LEPEEEEEVELELM-PVDLGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQ---- 366

Query: 433 PQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCG 487
            Q+  Q +   Q  E    Q+ + P E   +Q   Q +++ + PE    +V   G
Sbjct: 367 -QLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 19/107 (17%)

Query: 5   QQQQQLQQQ-------QQQLQQLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAV 55
           QQQ+QLQQQ       QQQ +QLQQQQL  QQ+QLQQQQ  Q Q+ LQQ   Q  L +  
Sbjct: 189 QQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQEQLQQ---QQQLLLLQ 245

Query: 56  SRGLPPQQPQQPLLNLQGTNSASLL---NGSMLQRALLLQQLQGLDQ 99
            +G    Q QQ LL  Q       L     + LQ+ LLLQQ + L Q
Sbjct: 246 QQG----QLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 40/96 (41%), Positives = 47/96 (48%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           M  QQQ Q  Q Q+QQ  Q QQ+QLQ QQ Q+QQ+LQ Q+ LQQ   +  L       L 
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212

Query: 61  PQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQG 96
            QQ  Q    LQ             Q+ LLL Q QG
Sbjct: 213 QQQLLQQQEQLQQQQFQQQQEQLQQQQQLLLLQQQG 248



 Score = 57.0 bits (136), Expect = 8e-08
 Identities = 35/66 (53%), Positives = 40/66 (60%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQ 63
           QQQQ+QLQQQQQ L   QQ QLQQQ LQQQQ    QQLL+Q   Q    + + +    QQ
Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288

Query: 64  PQQPLL 69
            QQ  L
Sbjct: 289 QQQQQL 294



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 47/102 (46%), Positives = 57/102 (55%), Gaps = 9/102 (8%)

Query: 5   QQQQQLQQQQQQLQ--QLQQQQL--QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSR--G 58
           Q+QQ+LQQQQ+QLQ  Q Q+QQ+  QQ+QLQQQ  +Q QQLLQQ   Q      + +   
Sbjct: 165 QEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQ--VQEQQLLQQQQEQLQQQQLLQQQEQ 222

Query: 59  LPPQQPQQPLLNLQGTNSASLL-NGSMLQRALLLQQLQGLDQ 99
           L  QQ QQ    LQ      LL     LQ+ LL QQ   L Q
Sbjct: 223 LQQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQ 264



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 39/69 (56%), Positives = 42/69 (60%), Gaps = 5/69 (7%)

Query: 5   QQQQQLQQQ--QQQLQQLQQQQLQQQ--QLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP 60
           QQQ QLQQQ  QQQ  QLQQQ L+QQ  QLQQQ LLQ Q+ LQQ   Q  L     + L 
Sbjct: 245 QQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQ-LQ 303

Query: 61  PQQPQQPLL 69
            QQ Q P L
Sbjct: 304 QQQLQPPPL 312



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 38/79 (48%), Positives = 45/79 (56%), Gaps = 10/79 (12%)

Query: 3   SQQQQQQLQQQQQQLQQ--LQQQQLQQQQLQQQQLLQLQQ-LLQQSPPQAPLPMAVSRGL 59
           +Q QQQ L+QQQ QLQQ  L QQQ Q QQ QQQQLLQ QQ  LQQ   Q P        L
Sbjct: 260 AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPP-------PL 312

Query: 60  PPQQPQQPLLNLQGTNSAS 78
            P++ ++  L L   +  S
Sbjct: 313 EPEEEEEVELELMPVDLGS 331



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 42/111 (37%), Positives = 49/111 (44%), Gaps = 20/111 (18%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQL-------------QQQQLQQQQLLQLQQLLQQSPPQAP 50
           QQ QQ  QQQ  QLQQ + Q +             QQQQLQ QQ+ Q QQ LQQ   Q  
Sbjct: 120 QQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQV-QEQQRLQQQQEQLQ 178

Query: 51  LPMAVSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQ 99
              A  + +  QQ Q      Q      LL      LQ+  LLQQ + L Q
Sbjct: 179 TQQAQEQQVLQQQEQLQ----QQVQEQQLLQQQQEQLQQQQLLQQQEQLQQ 225



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 31/74 (41%), Positives = 45/74 (60%), Gaps = 6/74 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQ---QQQLQQ--QQLLQLQQLLQQSPPQAPLPMAVSRG 58
           +QQ+Q+L++QQ+  +Q +Q+QLQ   Q++LQQ  QQL Q QQ L+Q   Q  L   V  G
Sbjct: 336 EQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLEL-TPVELG 394

Query: 59  LPPQQPQQPLLNLQ 72
              Q+ Q  L  +Q
Sbjct: 395 AQQQEVQLELTPVQ 408



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 42/111 (37%), Positives = 48/111 (43%), Gaps = 20/111 (18%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQ----LQQQQLQ--QQQLLQLQQLLQQS------PPQAPL 51
           Q +QQ   QQQ Q +QLQQ Q    LQQQ  Q  QQQL QLQQ   QS       P+  L
Sbjct: 93  QLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152

Query: 52  --------PMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQL 94
                   P  V      QQ Q+ L   Q      L     LQ+ +  QQL
Sbjct: 153 MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQL 203



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 81/377 (21%), Positives = 144/377 (38%), Gaps = 40/377 (10%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNL 71
           Q++ QLQQL+QQ   QQQ Q +QL            Q P P    +  P Q  QQ L  L
Sbjct: 86  QRELQLQQLEQQPEPQQQPQHEQL------------QQPQPHLELQQQPQQDGQQQLSQL 133

Query: 72  QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPG 131
           Q     S+ +  +     L+ Q Q L     P    +   L      L   +        
Sbjct: 134 QQEKHQSVHHQELKPELQLMHQQQQL----QPQQVQEQQRLQQQQEQLQTQQ--AQEQQV 187

Query: 132 LAAPSLTPPQLATPN-LQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSS 190
           L        Q+     LQQ   Q  +Q LL        +   QF    +  Q+Q +    
Sbjct: 188 LQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQE---QLQQQQF----QQQQEQLQQQQQ 240

Query: 191 TTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE 250
               ++    Q   ++ +    +  ++  E +    + Q L    E + ++++    +  
Sbjct: 241 LLLLQQQGQLQQQLLQQQQ--AQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQ- 297

Query: 251 PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPR 310
             +  +L  ++L+    P E E   +++++  P   + +  + +      E    Q L R
Sbjct: 298 --QQEQLQQQQLQ--PPPLEPEEEEEVELELMP---VDLGSEQELEQQRQELERQQELER 350

Query: 311 FQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAE 370
            Q    Q+Q ++Q + Q      + Q Q   Q++ Q + +P  L  QQ++VQ +L     
Sbjct: 351 -QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQLEL---TP 406

Query: 371 PQKQVQPQVQPQAHSQG 387
            Q ++Q ++ P A   G
Sbjct: 407 VQPELQLELVPAAGGGG 423



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 4/66 (6%)

Query: 4   QQQQQQLQQQ-QQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQ 62
           QQ+Q+QLQ + Q++LQQL+QQ  QQQQ  +QQ +QL+    +   Q      V   L P 
Sbjct: 351 QQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQ---QQEVQLELTPV 407

Query: 63  QPQQPL 68
           QP+  L
Sbjct: 408 QPELQL 413



 Score = 37.7 bits (86), Expect = 0.048
 Identities = 19/47 (40%), Positives = 33/47 (70%), Gaps = 5/47 (10%)

Query: 7   QQQLQQQQQQLQQLQQQQLQQQQLQ-----QQQLLQLQQLLQQSPPQ 48
           +Q+L+QQ+Q+L++ Q+ + QQ+Q Q     Q++L QL+Q L+Q   Q
Sbjct: 332 EQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQ 378



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 47/175 (26%), Positives = 64/175 (36%), Gaps = 47/175 (26%)

Query: 4   QQQQQQLQQQQQQLQQLQQQ----------------------------------QLQQQQ 29
           QQQQQ LQQQQ+QLQQ Q Q                                  + QQ+ 
Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQELERQQEL 348

Query: 30  LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRAL 89
            +QQ+  QLQ  LQ+   Q      + + L  QQ Q     +Q   +   L     +  L
Sbjct: 349 ERQQEQRQLQLKLQEELQQ------LEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402

Query: 90  LLQQLQGLDQFAMPPATYDTAGLT--MPTATLGNLRGYG-----MASPGLAAPSL 137
            L  +Q   Q  + PA           P A +    GY      M  P +AAP++
Sbjct: 403 ELTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPPGYVVVQELMVLPAVAAPAV 457


>gi|148612879 polyhomeotic like 3 [Homo sapiens]
          Length = 995

 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 156/658 (23%), Positives = 236/658 (35%), Gaps = 108/658 (16%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           Q  QQ+   QQQ   L    LQQQ L   QL  L          A +  ++S G P   P
Sbjct: 75  QYLQQMYAAQQQHLMLHTAALQQQHLSSSQLQSL----------AAVQASLSSGRPSTSP 124

Query: 65  QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT--AGLTMPTATLGNL 122
              +      +  S+   +    A L+ + Q          T  T   G T PT T    
Sbjct: 125 TGSVTQQSSMSQTSINLSTSPTPAQLISRSQA-SSSTSGSITQQTMLLGSTSPTLTASQA 183

Query: 123 RGYGMASPGLAAPSLTP-------PQLATPNLQQFFPQATR-QSL-LGPPPVGVPMNPSQ 173
           + Y  A   +  P+ T        P +++ +       AT+ Q+L L    +GV      
Sbjct: 184 QMYLRAQMLIFTPATTVAAVQSDIPVVSSSSSSSCQSAATQVQNLTLRSQKLGV------ 237

Query: 174 FNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE------ 227
            + S   P K    + S T     ++  +  +  +   PE +++   P +++        
Sbjct: 238 LSSSQNGPPKSTSQTQSLTICHNKTTVTSSKISQRDPSPESNKKGESPSLESRSTAVTRT 297

Query: 228 ---DQDLPPC------PEDIAKEKRTPAPEPEPCEAS--ELPAKRLRSSEEP------TE 270
               Q + P       P  + K ++ P   P P + S  +L  ++ +   +P      T+
Sbjct: 298 SSIHQLIAPASYSPIQPHSLIKHQQIPLHSP-PSKVSHHQLILQQQQQQIQPITLQNSTQ 356

Query: 271 KEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRI 330
             PP Q  +  Q       P   Q+    P  +++   P          AQ      P  
Sbjct: 357 DPPPSQHCIPLQNHGLPPAPSNAQSQHCSP--IQSHPSPLTVSPNQSQSAQQSVVVSPPP 414

Query: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQ---- 386
           P + +Q  P +    Q    P  LV    Q  P LQQ    Q Q   Q+   +H      
Sbjct: 415 PHSPSQ-SPTIIIHPQALIQPHPLVSSALQPGPNLQQSTANQVQATAQLNLPSHLPLPAS 473

Query: 387 -----GPRQVQL-----QQEAEPLKQVQPQVQ---------PQAHSQPPRQV-QLQLQKQ 426
                GP Q        QQ   P  Q    +Q         PQ  + PP Q+  L LQ  
Sbjct: 474 PVVHIGPVQQSALVSPGQQIVSPSHQQYSSLQSSPIPIASPPQMSTSPPAQIPPLPLQSM 533

Query: 427 VQTQTYPQVHTQAQPSVQ-----PQEHPPAQVSVQPPEQTHEQPHT---QPQVSLLAPEQ 478
              Q  P++ +Q Q  VQ      +E P A+  VQ P QT   P T     QV   AP  
Sbjct: 534 QSLQVQPEILSQGQVLVQNALVSEEELPAAEALVQLPFQTLPPPQTVAVNLQVQPPAPVD 593

Query: 479 TPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
            PVV     VC  EMP ++ E    M++T P P             S   + VG  E+  
Sbjct: 594 PPVVYQVEDVCEEEMPEESDEC-VRMDRTPPPP-----------TLSPAAITVGRGEDLT 641

Query: 536 REMPGV----WGAGGSLKVTILQSSDSRAFSTVPLTP--VPRPSDSVSSTPAATSTPS 587
            E P +      A  S+  ++++S    +  +VP  P  +P  +   +ST   +S PS
Sbjct: 642 SEHPLLEQVELPAVASVSASVIKSPSDPSHVSVPPPPLLLPAATTRSNSTSMHSSIPS 699


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 135/528 (25%), Positives = 194/528 (36%), Gaps = 69/528 (13%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLP----MAVSR 57
           QQQQQQ QQQQQQ QQ QQQQLQ +  QQ Q  Q Q +  Q  +P Q P+P       S 
Sbjct: 265 QQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSG 324

Query: 58  GLPPQQPQQPLLNL---QGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTM 114
            L P   Q  L  +   QG   A  L G M Q+      L  +   + PP  Y       
Sbjct: 325 ALQPPPAQGSLGTMTANQGWKKAP-LPGPMQQQLQARPSLATVQTPSHPPPPYPFGS--- 380

Query: 115 PTATLGNLRGYGMASPG----------LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPP 164
             A+  +     M++PG             PS  P  L  P+L    P ++  S     P
Sbjct: 381 QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSP 440

Query: 165 VGVP-MNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
              P +N +Q  +  R PQ          P    S  +   V+  + PP       +P  
Sbjct: 441 ASSPTVNQTQQQMGPRPPQNNPLPQGFQQP--VSSPGRNPMVQQGNVPPNFMVMQQQPPN 498

Query: 224 DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
             P  Q L P    + K        P    A +     ++     T    PG      Q 
Sbjct: 499 QGP--QSLHPGLGGMPKRL------PPGFSAGQANPNFMQGQVPSTTATTPGN-SGAPQL 549

Query: 284 QARMTVPK---QTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ-----PRIPSTDT 335
           QA   V     Q   P      +        QP ++ +   + +Q       P++  ++ 
Sbjct: 550 QANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNM 609

Query: 336 QVQPKLQKQAQTQTSPEHLVLQQKQV----------QPQLQQEAEPQKQVQPQVQPQAHS 385
           Q QP+    +Q     + +V  Q Q+           P +   A+   Q Q  V P + +
Sbjct: 610 QGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQN 669

Query: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQ---PPRQVQLQ---LQKQVQTQ----TYPQV 435
            GP   ++    + L Q  PQ+    H+Q   P  QV LQ   + +Q+ T        Q 
Sbjct: 670 LGPSPQRMTPPKQMLSQQGPQMM-APHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQF 728

Query: 436 HTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
           +TQ Q +V P    PAQ+     P  Q +    T      + P+Q PV
Sbjct: 729 NTQNQSNVMP---GPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPV 773



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 127/537 (23%), Positives = 185/537 (34%), Gaps = 109/537 (20%)

Query: 1    MFSQQQQ---QQLQQQQQQLQQLQQQQLQQQQL---QQQQLLQLQQLLQQ-----SPPQA 49
            M  Q QQ    QL    QQ+   Q Q +QQQ     Q   +L   QL+ Q     +PP  
Sbjct: 609  MQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQ 668

Query: 50   PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQGLDQFAMPPATYD 108
             L  +  R  PP+Q    +L+ QG    +  N  M  Q  +LLQQ   ++Q         
Sbjct: 669  NLGPSPQRMTPPKQ----MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQI-------- 716

Query: 109  TAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLA---TPNLQQFFPQATRQSLLGPPPV 165
                 M     GN + +   +     P   P Q+    TPN+Q    Q T Q      P 
Sbjct: 717  -----MTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGPTPNMQGNMVQFTGQMSGQMLPQ 769

Query: 166  GVPMNPSQFNLSGRNPQ-----------KQARTSSSTTPNRKDSSSQTMP----VEDKSD 210
              P+N S   + G   Q            Q     +TT N   S SQ MP     +    
Sbjct: 770  QGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMV 829

Query: 211  PP-----EGSEEAAE-----------PRMDTPEDQDLPPCPED----IAKEKRTPAPEPE 250
            PP     +G+  +             P    P    +  C ++    + K+    +P   
Sbjct: 830  PPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMS-CGQNPGFPVNKDVTLTSPLLV 888

Query: 251  PCEASELPAKR--LRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
                S++ A    + + +  T    P +   K  P+ +    +   TPD  P  LE    
Sbjct: 889  NLLQSDISAGHFGVNNKQNNTNANKPKK---KKPPRKKKNSQQDLNTPDTRPAGLEEAD- 944

Query: 309  PRFQPRVLQVQAQVQSQTQPRIPSTDT----------------QVQPKLQKQAQTQTSPE 352
               QP +   Q      + P++P                    Q+ P+L +       P 
Sbjct: 945  ---QPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPP 1001

Query: 353  HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
                 Q+Q QPQL Q+ +P    QPQ Q Q   Q    + L  + +P K V+  V    H
Sbjct: 1002 -----QQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDP-KSVRLPVSQNVH 1055

Query: 413  SQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQP 469
              PPR           +Q  P   + + P V      PA V   P +Q    P   P
Sbjct: 1056 --PPRG-----PLNPDSQRMPMQQSGSVP-VMVSLQGPASVPPSPDKQRMPMPVNTP 1104



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 63/270 (23%), Positives = 99/270 (36%), Gaps = 34/270 (12%)

Query: 222 RMDTPEDQDLPPCPEDIAKEKRTPAPEPE-------PCEASELPAKRLRSSEEPTEKEPP 274
           RM+ P    +PP   +++     P P PE       P   S+     L       +  P 
Sbjct: 175 RMNNPATVMIPP-GGNVSSSMMAPGPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPS 233

Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
           G L     P   ++V +Q    +           P+ Q +  Q Q Q Q Q Q +     
Sbjct: 234 GSLAPPHHPMQPVSVNRQMNPAN----------FPQLQQQQQQQQQQQQQQQQQQQQQQQ 283

Query: 335 TQVQPKLQKQAQTQ----TSPEHLVLQQKQVQP---QLQQEAEPQKQVQPQVQPQAHSQG 387
            Q+Q +  +Q Q Q      P+     Q  V P   QL   A      Q  +     +QG
Sbjct: 284 QQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQG 343

Query: 388 PRQVQLQQEAEPLKQVQPQ---VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQ---P 441
            ++  L    +   Q +P    VQ  +H  PP     Q   Q  T  +PQ+    Q   P
Sbjct: 344 WKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHT-NFPQMSNPGQFTAP 402

Query: 442 SVQPQEHPPAQV--SVQPPEQTHEQPHTQP 469
            ++  +  P++V   +Q P  T++ P + P
Sbjct: 403 QMKSLQGGPSRVPTPLQQPHLTNKSPASSP 432



 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 43/155 (27%), Positives = 63/155 (40%), Gaps = 16/155 (10%)

Query: 331 PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQ 390
           P  + ++QP+  + A    + + L+         +QQ++ P   + P   P      P  
Sbjct: 197 PGPNPELQPRTPRPASQSDAMDPLLSGL-----HIQQQSHPSGSLAPPHHPMQ----PVS 247

Query: 391 VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTY-PQVHTQAQP-SVQPQEH 448
           V  Q       Q+Q Q Q Q   Q  +Q Q Q Q+Q Q Q   PQ H Q QP  ++PQ  
Sbjct: 248 VNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFT 307

Query: 449 PPAQVSVQP-----PEQTHEQPHTQPQVSLLAPEQ 478
            P QV V P     P    + P  Q  +  +   Q
Sbjct: 308 APTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQ 342



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 76/291 (26%), Positives = 112/291 (38%), Gaps = 34/291 (11%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL-PPQ 62
            QQ Q QL QQQQ     Q Q  QQQQ QQQ ++ L  ++QQ P    LP  VS+ + PP+
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMML--MMQQDPKSVRLP--VSQNVHPPR 1058

Query: 63   QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT-LGN 121
             P    LN          +GS+     ++  LQG    A  P + D   + MP  T LG+
Sbjct: 1059 GP----LNPDSQRMPMQQSGSV----PVMVSLQGP---ASVPPSPDKQRMPMPVNTPLGS 1107

Query: 122  LRGYGMASPGLAAPSLTP-PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN 180
                 +       PS +P  ++A+       P+A+     G     VP  P+        
Sbjct: 1108 NSRKMVYQESPQNPSSSPLAEMAS------LPEAS-----GSEAPSVPGGPNNMPSHVVL 1156

Query: 181  PQKQ-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
            PQ Q   T     P+   ++    P +   +    S     P +  P     P  P   +
Sbjct: 1157 PQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRAS 1216

Query: 240  KE---KRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287
                  +TP   P   E SE+     R +       PP Q+ +   P+  +
Sbjct: 1217 PRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPP-QINIPLPPRPNL 1266



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 106/495 (21%), Positives = 181/495 (36%), Gaps = 66/495 (13%)

Query: 1    MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-QLQQLLQQSPPQ-----APLPMA 54
            M SQQ  Q +    Q +    Q  LQQ  + +Q +  Q+Q   QQ   Q      P P  
Sbjct: 683  MLSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQ 742

Query: 55   VSRGLPPQQPQQPLLNLQGTNSASLL--NGSMLQRALLLQQLQGLDQFAMPPATYDTAGL 112
            + RG P    Q  ++   G  S  +L   G +      +  +QG       P+ +     
Sbjct: 743  IMRG-PTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQH 801

Query: 113  TMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQS-------LLGPPPV 165
              P  T  N        P +   S+    +  P++Q     +   +           P  
Sbjct: 802  GDPATTANNDVSLSQMMPDV---SIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFS 858

Query: 166  GVPMNPSQFNLSGRNP----QKQARTSSSTTPN--RKDSSSQTMPVEDKSDPPEGSEEAA 219
            G P N +Q +  G+NP     K    +S    N  + D S+    V +K    + +  A 
Sbjct: 859  GAP-NGNQMS-CGQNPGFPVNKDVTLTSPLLVNLLQSDISAGHFGVNNK----QNNTNAN 912

Query: 220  EPRMDTPEDQDLPPCPEDIAKEKRTPAPEP---EPCEASELPAKRLRSSEEPTEKEPPGQ 276
            +P+   P     P   ++  ++  TP   P   E  +   LP ++  + +    K P   
Sbjct: 913  KPKKKKP-----PRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINLDNSGPKLP--- 964

Query: 277  LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
             +   +P    + P + +    +P  L   V P  QP   Q Q Q+  Q QP  PS    
Sbjct: 965  -EFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPS---- 1019

Query: 337  VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGP-----RQV 391
             QP+ Q+Q Q          QQ+Q+   L  + +P+    P  Q     +GP     +++
Sbjct: 1020 -QPQSQQQQQ----------QQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRM 1068

Query: 392  QLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPP 450
             +QQ       V  Q        P +Q + + +   + + +   V+ ++  +  P   P 
Sbjct: 1069 PMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQN--PSSSPL 1126

Query: 451  AQVSVQPPEQTHEQP 465
            A+++  P     E P
Sbjct: 1127 AEMASLPEASGSEAP 1141



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 49/166 (29%), Positives = 69/166 (41%), Gaps = 32/166 (19%)

Query: 339 PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAE 398
           P+LQ+Q Q Q        QQ+Q Q Q QQ+ + Q+Q+Q +   Q   Q P+ ++ Q  A 
Sbjct: 258 PQLQQQQQQQ--------QQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAP 309

Query: 399 PLKQVQP---QVQPQAHSQPPRQVQL------QLQKQVQTQTYPQVHTQAQPS---VQPQ 446
               V P   Q+   A   PP Q  L      Q  K+       Q   QA+PS   VQ  
Sbjct: 310 TQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTP 369

Query: 447 EHPP----------AQVSVQPPEQTHEQPHTQPQVSLL--APEQTP 480
            HPP          +Q     P+ ++    T PQ+  L   P + P
Sbjct: 370 SHPPPPYPFGSQQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVP 415



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 89/437 (20%), Positives = 132/437 (30%), Gaps = 98/437 (22%)

Query: 140 PQLATPNLQQFFPQATRQSLLGPP-----PVGV--PMNPSQFNLSGRNPQKQARTSSSTT 192
           P L+  ++QQ   Q+     L PP     PV V   MNP+ F    +  Q+Q +      
Sbjct: 219 PLLSGLHIQQ---QSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQ 275

Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------- 245
             ++    Q +         +   +   P+   P    +PP    +      P       
Sbjct: 276 QQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSL 335

Query: 246 -----------APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQ 294
                      AP P P +        L + + P+   PP     +   QA    P+ + 
Sbjct: 336 GTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSN 395

Query: 295 T--------------PDLLPEALEAQVL----PRFQPRVLQVQA--------QVQSQTQP 328
                          P  +P  L+   L    P   P   Q  +        Q Q Q  P
Sbjct: 396 PGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGP 455

Query: 329 RIPSTDTQVQ--------PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQ 380
           R P  +   Q        P      Q    P + ++ Q+Q   Q  Q   P     P+  
Sbjct: 456 RPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQSLHPGLGGMPKRL 515

Query: 381 PQAHSQGPRQVQLQQEAEP-----------LKQVQ---------------PQVQPQAHSQ 414
           P   S G       Q   P             Q+Q               PQ Q Q    
Sbjct: 516 PPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHG 575

Query: 415 PPRQVQLQL--------QKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
           PP  +Q  L         +Q  T   PQV+       QPQ+ PP+Q+     +    Q  
Sbjct: 576 PPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQG-QPQQGPPSQLMGMHQQIVPSQGQ 634

Query: 467 TQPQVSLLAPEQTPVVV 483
              Q   L P Q P+++
Sbjct: 635 MVQQQGTLNP-QNPMIL 650



 Score = 43.5 bits (101), Expect = 9e-04
 Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 7/117 (5%)

Query: 371 PQKQVQPQVQPQAHSQGPRQ------VQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQ 424
           P  ++QP+  P+  SQ          + +QQ++ P   + P   P       RQ+     
Sbjct: 199 PNPELQPRT-PRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANF 257

Query: 425 KQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
            Q+Q Q   Q   Q Q   Q Q+    Q+  +PP+Q  +Q     +    AP Q PV
Sbjct: 258 PQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPV 314



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 125/593 (21%), Positives = 199/593 (33%), Gaps = 100/593 (16%)

Query: 3    SQQQQQQLQQQQQQLQQLQQQQ------------------------LQQQQLQQQQLLQL 38
            SQ Q QQ QQQQQQ+  +   Q                         Q+  +QQ   + +
Sbjct: 1019 SQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPV 1078

Query: 39   QQLLQ------QSPPQAPLPMAVSRGL-----------PPQQP-QQPLLNL------QGT 74
               LQ       SP +  +PM V+  L            PQ P   PL  +       G+
Sbjct: 1079 MVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGS 1138

Query: 75   NSASLLNG--SMLQRALLLQ-QLQGLDQFAMPPATYDTAGLTMPTATLGNL-RGYGMASP 130
             + S+  G  +M    +L Q QL        P     T G T     + +L   +G   P
Sbjct: 1139 EAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFP 1198

Query: 131  GLAAPSLT----PPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRN---PQK 183
             +AAP+ T     P  A+P  + ++PQ          P  + ++P + N S      PQ 
Sbjct: 1199 NVAAPTQTSRPKTPNRASP--RPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQI 1256

Query: 184  QARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP-RMDTPEDQDLPPCPEDIAKEK 242
                      NR        P   K+     S     P    TP+   L     +  K+ 
Sbjct: 1257 NIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLDSVVVNSGKQS 1316

Query: 243  RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDL---- 298
             + A +     AS   ++R            PG+   KA    ++T+  QT    L    
Sbjct: 1317 NSGATK----RASPSNSRRSSPGSSRKTTPSPGRQNSKA---PKLTLASQTNAALLQNVE 1369

Query: 299  LPEALEAQVLPRFQPRV---------LQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
            LP  +     P   P V         L  Q    S         D +    + + +  Q 
Sbjct: 1370 LPRNVLVSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKESLNVPQDSDCQN 1429

Query: 350  SPEHLVLQQKQVQPQLQQEAEPQKQVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQPQVQ 408
            S      Q ++ Q  ++ +A P ++V+  V + Q+   G       Q ++P K    +  
Sbjct: 1430 S------QSRKEQVNIELKAVPAQEVKMVVPEDQSKKDG-------QPSDPNKLPSVEEN 1476

Query: 409  PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQ 468
                S   R+    L + +     P V T   P +   E  P  VS +  ++    P  Q
Sbjct: 1477 KNLVSPAMREAPTSLSQLLDNSGAPNV-TIKPPGLTDLEVTPPVVSGEDLKKASVIPTLQ 1535

Query: 469  PQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEI 518
               S   P  +  + H   +C   + P+  E    +  ++P  +   VS   I
Sbjct: 1536 DLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPVSSSSI 1588



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 110/513 (21%), Positives = 173/513 (33%), Gaps = 102/513 (19%)

Query: 20   LQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL 79
            +  QQ     + Q  L  +Q   QQ PP     M + + + P Q Q  ++  QGT +   
Sbjct: 591  MNNQQAGTSGVPQVNLSNMQGQPQQGPPSQL--MGMHQQIVPSQGQ--MVQQQGTLNPQ- 645

Query: 80   LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAP---- 135
             N  +L RA L+ Q Q +              +  P+  LG        SP    P    
Sbjct: 646  -NPMILSRAQLMPQGQMM--------------VNPPSQNLG-------PSPQRMTPPKQM 683

Query: 136  -SLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ-------ART 187
             S   PQ+  P+ Q   PQ        P    +  N  Q N    N Q Q       A+ 
Sbjct: 684  LSQQGPQMMAPHNQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQI 743

Query: 188  SSSTTPNRKDSSSQ-TMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPA 246
                TPN + +  Q T  +  +  P +G    +  ++   + Q L P           P 
Sbjct: 744  MRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNNSPSQVMGIQGQVLRP-----------PG 792

Query: 247  PEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQ 306
            P P   +    PA    +    ++  P   +Q     Q  M  P          +A++  
Sbjct: 793  PSPHMAQQHGDPATTANNDVSLSQMMPDVSIQ-----QTNMVPPHV--------QAMQGN 839

Query: 307  VLP--RFQPRVLQVQA---------QVQSQTQPRIPSTD--TQVQPKLQKQAQTQTSPEH 353
                  F    +   A         Q+     P  P     T   P L    Q+  S  H
Sbjct: 840  SASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQSDISAGH 899

Query: 354  LVLQQKQVQPQLQQEAEPQKQVQPQV----QPQAHSQGPRQVQLQQEAEP---------L 400
              +  KQ      +   P+K+  P+     Q   ++   R   L++  +P         L
Sbjct: 900  FGVNNKQNNTNANK---PKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGEQGINL 956

Query: 401  KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ-PQEHP----PAQVSV 455
                P++ P+  ++PP      ++++   Q  PQ+     P  Q PQ+ P    P Q   
Sbjct: 957  DNSGPKL-PEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQP 1015

Query: 456  QPPEQTHEQPHTQPQ---VSLLAPEQTPVVVHV 485
             PP Q   Q   Q Q   + +L  +Q P  V +
Sbjct: 1016 PPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRL 1048



 Score = 38.5 bits (88), Expect = 0.028
 Identities = 61/305 (20%), Positives = 104/305 (34%), Gaps = 31/305 (10%)

Query: 18   QQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSA 77
            Q ++Q+ LQQ      QL+Q      Q P Q P P    +  PP  P QP    Q     
Sbjct: 976  QPVEQRPLQQ---MPPQLMQHVAPPPQPPQQQPQPQLPQQQQPP-PPSQPQSQQQQQQQQ 1031

Query: 78   SLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSL 137
             ++   M+Q+     +L        P    +     MP    G++         L  P+ 
Sbjct: 1032 QMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSV----PVMVSLQGPAS 1087

Query: 138  TPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQ----FNLSGRNPQKQARTSSSTTP 193
             PP   +P+ Q+            P PV  P+  +     +  S +NP        ++ P
Sbjct: 1088 VPP---SPDKQRM-----------PMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLP 1133

Query: 194  NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCE 253
                S + ++P    + P        +  M  P+    P      A  ++ P        
Sbjct: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSH 1193

Query: 254  ASELPAKRLRSSEEPTEKEPPGQLQVKA-QPQARMTVPKQTQTPD--LLPEALEAQVLPR 310
                P   + +  + +  + P +   +   PQ     P  T+  +  L PE L A +   
Sbjct: 1194 GHHFP--NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGL 1251

Query: 311  FQPRV 315
            F P++
Sbjct: 1252 FPPQI 1256


>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
          Length = 961

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 83/302 (27%), Positives = 113/302 (37%), Gaps = 38/302 (12%)

Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRM------DTPEDQDLPPCPEDIAKEKRTPAPEPEP 251
           ++ +T P    +DP   +E +  PR         P    LP  P    +++ T  P P+ 
Sbjct: 343 AAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQA 402

Query: 252 CEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEAL--EAQVLP 309
             +S  P   L S  +P  + PP Q   + Q +     P   QTP    + L  +AQ  P
Sbjct: 403 AGSSNQPGL-LASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPSTQAQGLPAQAQATP 461

Query: 310 RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEA 369
           + Q ++   Q Q Q Q  P                   Q  P     QQ+Q Q Q  Q  
Sbjct: 462 QHQQQLFLKQQQQQQQPPP------------------AQQQPAGTFYQQQQAQTQQFQAV 503

Query: 370 EPQKQVQPQVQPQAHSQGPRQVQL------QQEAEPLKQVQPQVQPQAHSQP--PRQVQL 421
            P  Q     Q    SQG  Q QL      QQ+ +  +Q Q Q+    H Q    +Q  L
Sbjct: 504 HPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAAL 563

Query: 422 QLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSV--QPPEQTHEQPHTQPQ-VSLLAPEQ 478
           Q +  +     PQ    A P   P + P  Q  V  QP  QT   P  Q Q V  L P  
Sbjct: 564 QQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPS 623

Query: 479 TP 480
           +P
Sbjct: 624 SP 625



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 70/305 (22%), Positives = 110/305 (36%), Gaps = 54/305 (17%)

Query: 162 PPPVGVPMNPSQFNLSGRNPQKQAR-------TSSSTTPNRKDSSSQT------MPVEDK 208
           P P  +P        + +  Q +AR       T +S  P ++  + QT      +P++  
Sbjct: 328 PIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPA 387

Query: 209 ---------SDPPEGSEEAAEPRMDTPEDQDLP------PCPEDIAKEKRTP-APEPEPC 252
                      PP+ +  + +P +     Q  P      P P+  AK+ + P  P+  P 
Sbjct: 388 LTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPPSQPLPQTQAKQPQAPPTPQQTPS 447

Query: 253 -EASELPAKRLRSSEE----------------PTEKEPPGQL--QVKAQPQARMTVPKQT 293
            +A  LPA+   + +                 P +++P G    Q +AQ Q    V   T
Sbjct: 448 TQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPAT 507

Query: 294 QTPDL--LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSP 351
           Q P +   P   +     +      Q Q Q Q Q Q +  +T    Q  + +QA  Q  P
Sbjct: 508 QQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKP 567

Query: 352 EHLVLQQKQVQP----QLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQV 407
                QQ Q QP    Q     EP  Q   + QP+  +  P  VQ Q+         P+ 
Sbjct: 568 TMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPPSSPKT 627

Query: 408 QPQAH 412
           Q   H
Sbjct: 628 QRAGH 632



 Score = 53.5 bits (127), Expect = 9e-07
 Identities = 69/238 (28%), Positives = 87/238 (36%), Gaps = 59/238 (24%)

Query: 234 CPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
           CP    +    PA  PEP +ASE  AK                   K QP+AR+T P  T
Sbjct: 319 CPIPNVQNSPIPAKLPEPVKASEAAAK-------------------KTQPKARLTDPIPT 359

Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
                     E  + PR +P+          QTQP       Q     +K+A  Q  P+ 
Sbjct: 360 T---------ETSIAPRQRPKA--------GQTQPNPGILPIQPALTPRKRATVQPPPQ- 401

Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
                   QP L           PQ +PQA    P Q   Q +A+     QPQ  P    
Sbjct: 402 --AAGSSNQPGLLASV-------PQPKPQAP---PSQPLPQTQAK-----QPQAPPTPQQ 444

Query: 414 QPPRQVQ-LQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQ 470
            P  Q Q L  Q Q   Q   Q+  + Q   Q Q+ PPAQ   QP    ++Q   Q Q
Sbjct: 445 TPSTQAQGLPAQAQATPQHQQQLFLKQQQ--QQQQPPPAQ--QQPAGTFYQQQQAQTQ 498



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 31/67 (46%), Positives = 34/67 (50%), Gaps = 6/67 (8%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQA------PLPMAVSR 57
           QQ  Q   QQQQQ QQ QQQQ     L QQQL+  Q  LQQ P  A      P P A  +
Sbjct: 525 QQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAAPQ 584

Query: 58  GLPPQQP 64
             P Q+P
Sbjct: 585 PAPAQEP 591



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 68/237 (28%), Positives = 89/237 (37%), Gaps = 33/237 (13%)

Query: 5   QQQQQLQQQQQQLQQLQQQQ------LQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
           QQQ  L+QQQQQ Q    QQ       QQQQ Q QQ   +    QQ P  A  P+    G
Sbjct: 464 QQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAVHPATQQ-PAIAQFPVVSQGG 522

Query: 59  LPP-------QQPQQPLLNLQGTNSASLLNGS--MLQRALLL--------QQLQGLDQFA 101
                     QQ QQ     Q    A+ L+    M Q+A L         QQ Q     A
Sbjct: 523 SQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAA 582

Query: 102 MPPATYDTAGLTMPTATLGNLRGY-GMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLL 160
             PA      +  P      ++     A  G    SLTPP  ++P  Q+   +     + 
Sbjct: 583 PQPAPAQEPAIQAPVRQQPKVQTTPPPAVQGQKVGSLTPP--SSPKTQRAGHRRILSDVT 640

Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSS--TTPNRKDSSSQTMPVEDKSDPPEGS 215
                GVP + S   L     +     S S  TTP+    +SQ    ++  +P EGS
Sbjct: 641 HSAVFGVPASKSTQLLQAAAAEASLNKSKSATTTPSGSPRTSQ----QNVYNPSEGS 693


>gi|91208418 transcription elongation regulator 1 isoform 2 [Homo
           sapiens]
          Length = 1077

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 101/382 (26%), Positives = 136/382 (35%), Gaps = 52/382 (13%)

Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
           GPPP+  P  P  F +  R P    R      P   D +   MP      PP G      
Sbjct: 42  GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96

Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVK 280
           P    P    +PP P  +        P   P  A   PA           K P G++   
Sbjct: 97  PPFMPPPMSSMPPPPGMMF------PPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150

Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
               AR      T+ PD +    ++++ P     +L  QAQVQ+Q Q        Q Q +
Sbjct: 151 ---NARTRESAWTK-PDGVKVIQQSELTP-----MLAAQAQVQAQAQ-----AQAQAQAQ 196

Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
            Q QAQ Q   +     Q Q Q Q Q +A+ Q Q Q Q Q QA +Q   QVQ Q +A+ +
Sbjct: 197 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAV 256

Query: 401 -------KQVQPQVQPQAHSQPPRQ-----------VQLQLQKQVQTQTYPQVHTQAQPS 442
                      P V     S  P              Q       Q QT     + A P+
Sbjct: 257 GASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPT 316

Query: 443 VQPQEHPPAQVSVQPPEQTHEQ------PHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
           V      P    VQ   Q H Q      PH+ PQ +   P   PV+V    + +P   + 
Sbjct: 317 VSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIP 376

Query: 497 AGG---GMEKTLPEPVGTQVSM 515
             G   GM   +   +  QV++
Sbjct: 377 LPGVLPGMAPPIVPMIHPQVAI 398



 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)

Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
           +  Q +     + PP        P M        PP P  +    R P P P P      
Sbjct: 22  AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65

Query: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
           P  R           PPG +     P      P   Q P  +P  + +   P    F P 
Sbjct: 66  PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118

Query: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
           +  V A       P +P T+   V+ K          A+T+    T P+ + V+QQ ++ 
Sbjct: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174

Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
           P L  +A+ Q Q Q Q Q QA +Q   Q Q Q +A    Q Q Q Q QA +Q   Q Q Q
Sbjct: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230

Query: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
            Q Q Q Q   QV  Q Q  VQ Q      V    P  +   P      S   P  T
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282



 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 86/442 (19%), Positives = 134/442 (30%), Gaps = 59/442 (13%)

Query: 26  QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
           + ++    +L   QQ   +    AP P AV RG PP  +P  P   ++G           
Sbjct: 10  ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64

Query: 85  LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
                          F  PP  +D     MP          G   P +  P L  P    
Sbjct: 65  -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101

Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
           P +    P        G PPV  P  P+        P  +     + TP+ K        
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154

Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
            E     P+G +   +  + TP              + +  A      +A +  A+    
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212

Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
           ++   + +   Q Q +AQ QA+     Q Q    +   ++AQ +    P        V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272

Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
            T    PS+ T         AQT ++P      Q Q        A P   V         
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320

Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV---------QLQLQKQVQTQTYPQV 435
           +  P    +Q   +P  Q  P   P +  QP   +           ++         P V
Sbjct: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGV 380

Query: 436 HTQAQPSVQPQEHPPAQVSVQP 457
                P + P  HP   ++  P
Sbjct: 381 LPGMAPPIVPMIHPQVAIAASP 402



 Score = 40.0 bits (92), Expect = 0.010
 Identities = 77/311 (24%), Positives = 106/311 (34%), Gaps = 44/311 (14%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q Q +  S P    P  AVS      
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNL 122
            P         T S +    S+ Q              A+  AT  T  ++ P  T   +
Sbjct: 278 TP-------SSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVAT-PTVSVSTPAPTATPV 329

Query: 123 RGYGMASPGLAAP----SLTPPQLATPNLQQFFPQATRQSLLGPP-----------PVGV 167
           +      P    P    S+  P  A P          R  L G P           P  V
Sbjct: 330 QTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVLPGMAPPIV 389

Query: 168 PMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPE 227
           PM   Q  ++         T+ S     K +  +T    +++      E   E   +  E
Sbjct: 390 PMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRT-----LESTWEKPQELKE 444

Query: 228 DQDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEKEPPGQLQV 279
            + L    E I +  + P+ EP P E       E P K ++     EE TE+E   Q   
Sbjct: 445 KEKL---EEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQ--- 498

Query: 280 KAQPQARMTVP 290
           KA+P A   +P
Sbjct: 499 KAKPVATAPIP 509


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 86/315 (27%), Positives = 124/315 (39%), Gaps = 73/315 (23%)

Query: 5   QQQQQLQQQQQQLQQL-------QQQQLQQQQLQQQQLLQLQQLLQQSP---PQAPLPMA 54
           Q QQQ+QQQQQQLQ++       QQQQ QQQQ QQQQ LQ Q  +QQ P   PQ P   A
Sbjct: 226 QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA 285

Query: 55  VSRGL----------PPQQPQQPLLNLQGTNSASLLNGSMLQRALL--LQQLQGLDQFAM 102
           + + L          PP QPQQP +     N  S L      + L+   Q L G   +  
Sbjct: 286 LPQQLQQMHHTQHHQPPPQPQQPPV---AQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 103 PPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP 162
           PP  +  A + +                        PP       QQ   Q  + + +  
Sbjct: 343 PPLKFVRAPMVVQ----------------------QPPVQPQVQQQQTAVQTAQAAQMVA 380

Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPR 222
           P V V              Q      SS +P ++  + Q+MP      PP+ S +  +P 
Sbjct: 381 PGVQV-------------SQSSLPMLSSPSPGQQVQTPQSMP-----PPPQPSPQPGQPS 422

Query: 223 MDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
                +    P P   +     P+P P+P + S + A+  ++   P+    PG L     
Sbjct: 423 SQPNSNVSSGPAP---SPSSFLPSPSPQPSQ-SPVTARTPQNFSVPS----PGPLNTPVN 474

Query: 283 PQARMTVPKQTQTPD 297
           P + M+    +Q  +
Sbjct: 475 PSSVMSPAGSSQAEE 489



 Score = 77.0 bits (188), Expect = 7e-14
 Identities = 101/365 (27%), Positives = 144/365 (39%), Gaps = 75/365 (20%)

Query: 275 GQLQVKAQPQARMTVPKQTQTPDLLPE--ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
           G L    QP +    P    T  + P   A+ +   P+ Q ++ QV  Q Q Q Q     
Sbjct: 114 GSLGAMGQPMSLSGQPPPG-TSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQ----Q 168

Query: 333 TDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH-----SQG 387
              Q Q  LQ+Q Q Q   +    QQ  +Q Q Q   + Q+Q+Q Q Q Q H      Q 
Sbjct: 169 FQQQQQAALQQQQQQQQQ-QQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQN 227

Query: 388 PRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQE 447
            +Q+Q QQ+     Q+Q   Q Q   Q  +Q Q Q Q+Q   Q  P +    QP +Q  +
Sbjct: 228 QQQIQQQQQ-----QLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ---QPPMQQPQ 279

Query: 448 HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP---------DAVEAG 498
            PP+Q   Q  +Q H   H QP      P+Q PV  +    ++PP          A    
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQ---PQQPPVAQNQPS-QLPPQSQTQPLVSQAQALP 335

Query: 499 GGMEKTLP-------------EPVGTQVSMEEIQNESACGLDVGECENRAREM--PGVWG 543
           G M  T P              PV  QV  ++   ++A          +A +M  PGV  
Sbjct: 336 GQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTA----------QAAQMVAPGVQV 385

Query: 544 AGGSLKVTILQSSDSRAFSTVPLTPVPRPS-----------DSVSSTPAAT-----STPS 587
           +  SL +    S   +  +   + P P+PS            +VSS PA +      +PS
Sbjct: 386 SQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPS 445

Query: 588 KQALQ 592
            Q  Q
Sbjct: 446 PQPSQ 450



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 90/335 (26%), Positives = 121/335 (36%), Gaps = 26/335 (7%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQ---------LLQLQQLLQQSPPQAP--LP 52
           QQQQQQ QQQQQ   Q QQQQ QQQQ Q QQ         ++Q QQ LQQ   Q    + 
Sbjct: 163 QQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIK 222

Query: 53  MAVSRGLPPQQPQQPL-----LNLQGTNSASLLNGSMLQRALLLQ---QLQGLDQFAMPP 104
           +        QQ QQ L     L LQ             Q+AL  Q   Q   + Q   PP
Sbjct: 223 LHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPP 282

Query: 105 ATYDTAGLTMPTATLGNLRGYGMASPGLA--APSLTPPQLATPNLQQFFPQATRQSLLGP 162
           +      L     T  +        P +A   PS  PPQ  T  L         Q L   
Sbjct: 283 SQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQ 342

Query: 163 PPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDP----PEGSEEA 218
           PP+     P         PQ Q + ++  T       +  + V   S P    P   ++ 
Sbjct: 343 PPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402

Query: 219 AEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQ 278
             P+   P  Q  P   +  ++     +  P P  +S LP+   + S+ P     P    
Sbjct: 403 QTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFS 462

Query: 279 VKAQPQARMTV-PKQTQTPDLLPEALEAQVLPRFQ 312
           V +       V P    +P    +A E Q L + +
Sbjct: 463 VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLK 497


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 90/346 (26%), Positives = 130/346 (37%), Gaps = 47/346 (13%)

Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
           SPGL       PQL  P+    F  A        P   VP + +Q       PQ  +  S
Sbjct: 369 SPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQ-------PQTGSGAS 421

Query: 189 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 248
            +    ++ S +Q +           +      RM   + Q  P    + +    +  P 
Sbjct: 422 RALPSWQEVSHAQQLK-------QIAANRQQHARMQQHQQQHQPT---NWSALPSSAGPS 471

Query: 249 PEPCEASELPAKRL-------RSSEEPTEKEPPGQLQV------KAQPQAR---MTVPKQ 292
           P P    ++P+          +SS  P      GQ +V      KA P A+   + V  Q
Sbjct: 472 PGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQ 531

Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
            Q P  L  +      P  +PR        Q  T+P       Q   ++     +Q  P 
Sbjct: 532 -QKPQDLSRSFINNPHPAMEPR--------QGNTKPLFHFNSDQANQQMPSVLPSQNKPS 582

Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
            L   Q+Q Q Q QQ+ + Q+Q Q Q Q Q   Q     Q QQ++    Q Q Q Q    
Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ-----QQQQQSSISAQQQQQQQSSIS 637

Query: 413 SQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPP 458
           +Q  +Q Q Q Q+Q Q Q   Q   Q QPS QP +  P+Q  ++ P
Sbjct: 638 AQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSP 683



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 45/98 (45%), Positives = 50/98 (51%), Gaps = 6/98 (6%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQ-----QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
           QQQQQQ QQQQQQ QQ QQQQ Q     QQQ QQQ  +  QQ  QQ   Q        + 
Sbjct: 599 QQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQ 658

Query: 59  LPPQQPQQPLLNLQGTNSASLLNGSM-LQRALLLQQLQ 95
              QQ Q      Q   S  LL   + LQ+ LLLQQ+Q
Sbjct: 659 QQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQ 696



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 47/155 (30%), Positives = 65/155 (41%), Gaps = 8/155 (5%)

Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
           Q P +LP   +  +L   Q +  Q Q Q Q Q Q        Q Q + Q+Q Q Q   + 
Sbjct: 570 QMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQ-------QQQQQQQQQQQQQQQQQS 622

Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHS 413
            +  Q+Q Q Q    A+ Q+Q Q Q Q Q   Q  +Q Q QQ+           QP   S
Sbjct: 623 SISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRS 682

Query: 414 QPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEH 448
             P Q +L LQ Q+Q Q    +  Q     +  +H
Sbjct: 683 PLPLQQKLLLQ-QMQNQPIAGMGYQVSQQQRQDQH 716



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 32/66 (48%), Positives = 38/66 (57%), Gaps = 1/66 (1%)

Query: 6   QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
           QQQQ QQQQQQ QQ QQQQ QQQQ QQ      Q L  Q   ++PLP+   + L  Q   
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQ-QKLLLQQMQN 697

Query: 66  QPLLNL 71
           QP+  +
Sbjct: 698 QPIAGM 703



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 56/216 (25%), Positives = 83/216 (38%), Gaps = 25/216 (11%)

Query: 235 PEDIAKEK-RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQT 293
           P+D+++     P P  EP + +  P     S +              A  Q    +P Q 
Sbjct: 534 PQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQ--------------ANQQMPSVLPSQN 579

Query: 294 QTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
           + P LL    + Q   + Q +  Q Q Q Q Q Q +      Q     Q+Q Q Q+S   
Sbjct: 580 K-PSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS--- 635

Query: 354 LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH--SQGPRQVQLQQE--AEPLKQVQPQVQP 409
             +  +Q Q Q QQ+ + Q+Q Q Q Q Q    S  P Q    Q     PL   Q  +  
Sbjct: 636 --ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQ 693

Query: 410 QAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
           Q  +QP   +  Q+ +Q +   +  V     PS  P
Sbjct: 694 QMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSP 729



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 6/107 (5%)

Query: 3   SQQQQQQL------QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS 56
           S Q  QQ+      Q +   L   QQQQ QQQQ QQQQ  Q QQ  QQ   Q       S
Sbjct: 564 SDQANQQMPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSS 623

Query: 57  RGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP 103
                QQ QQ  ++ Q             Q+    QQ Q     + P
Sbjct: 624 ISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQP 670



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 42/112 (37%), Positives = 54/112 (48%), Gaps = 23/112 (20%)

Query: 4   QQQQQQLQQQQ----QQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGL 59
           QQQQQQ QQQQ    Q  Q L  Q L +  L  QQ L LQQ+  Q+ P A +   VS   
Sbjct: 654 QQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM--QNQPIAGMGYQVS--- 708

Query: 60  PPQQPQQPLLNLQGTNSA-----------SLLNGSM-LQRALLLQQLQGLDQ 99
             QQ +Q   ++ G N+            +  +G M  Q++LL QQL G  Q
Sbjct: 709 --QQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQ 758



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 73/335 (21%), Positives = 120/335 (35%), Gaps = 42/335 (12%)

Query: 1    MFSQQQ--QQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRG 58
            M SQQ    QQL  ++Q LQ+   +Q QQ  LQQQ L   +++     PQ  +   +SR 
Sbjct: 742  MNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQMLADAEKI----APQDQINRHLSRP 797

Query: 59   LPPQQPQ-------QPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAG 111
             P  + Q       QP     G +S   LN +      +          ++   ++ T  
Sbjct: 798  PPDYKDQRRNVGNMQPTAQYSGGSSTISLNSNQALANPVSTHTILTPNSSLLSTSHGTRM 857

Query: 112  LTMPTATLGNLRGYG---MASPGLAAPSLTPPQLATP-NLQQFFPQATRQSLLGPPPVGV 167
             ++ TA + N+  YG      P   + +    QL    N +Q         +  PP +G 
Sbjct: 858  PSLSTA-VQNMGMYGNLPCNQPNTYSVTSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGP 916

Query: 168  PMNPSQFNLS----GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
              N +         G + Q +   + S        +S  M   + + P   S+E    + 
Sbjct: 917  SNNNNVATFGAGSVGNSQQLRPNLTHSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQ 976

Query: 224  DTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE-EPTEKEPPGQL----Q 278
            +      +           R P   P     ++   + + S +       PP QL    Q
Sbjct: 977  EALTSAGV-----------RFPTGTPAAYTPNQSLQQAVGSQQFSQRAVAPPNQLTPAVQ 1025

Query: 279  VKAQPQARMTVPKQTQTP----DLLPEALEAQVLP 309
            ++   Q   T+  QT  P    +L P  L  Q+LP
Sbjct: 1026 MRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQILP 1060



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 80/422 (18%), Positives = 154/422 (36%), Gaps = 62/422 (14%)

Query: 6   QQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQ 65
           Q+    QQ +Q+   +QQ  + QQ QQQ        L  S   +P P    +   P   Q
Sbjct: 428 QEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGPSPGPFGQEKIPSPSFGQ 487

Query: 66  Q-------PLLNLQGTNSASLLNGSMLQRALLLQQLQGLD-QFAMPPATYDTAGLTMPTA 117
           Q       P+  + G +  S +  + + +A    Q   LD      P     + +  P  
Sbjct: 488 QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNP-- 545

Query: 118 TLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLS 177
                            P++ P Q  T  L  F      Q +  P  +     PS  + +
Sbjct: 546 ----------------HPAMEPRQGNTKPLFHFNSDQANQQM--PSVLPSQNKPSLLHYT 587

Query: 178 GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
            +  Q+Q +        ++    Q    + +      S +  + +  +            
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSS------------ 635

Query: 238 IAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPD 297
           I+ +++    + +  +  +   ++ +  ++P+ +  P Q  + +QP  R  +P Q +   
Sbjct: 636 ISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQ--PAQ-SLPSQPLLRSPLPLQQK--- 689

Query: 298 LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQ 357
           LL + ++ Q +     +V    +Q Q Q Q  +   +T   P     +   T   ++  Q
Sbjct: 690 LLLQQMQNQPIAGMGYQV----SQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQ 745

Query: 358 QKQVQPQLQQEAEP-QKQVQPQVQPQAHSQGPRQVQLQQE-AEPLKQVQPQVQPQAH-SQ 414
           Q  +  QL  + +  Q+Q+  Q Q         Q+ LQQ+     +++ PQ Q   H S+
Sbjct: 746 QSLLNQQLMGKKQTLQRQIMEQKQ---------QLLLQQQMLADAEKIAPQDQINRHLSR 796

Query: 415 PP 416
           PP
Sbjct: 797 PP 798


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 62/199 (31%), Positives = 92/199 (46%), Gaps = 29/199 (14%)

Query: 282  QPQARMTVPKQTQTPDLLPEALEAQVLP-RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
            Q Q++++   Q      LP A  + V P   QP+  Q  AQ Q QTQP+ P+     QP+
Sbjct: 2364 QRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPA-----QPE 2418

Query: 341  LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
            +Q Q + QT          + QP   Q ++PQ  V  Q QPQ++ QG   V++Q  +   
Sbjct: 2419 VQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQ--VAAQSQPQSNVQGQSPVRVQSPS--- 2473

Query: 401  KQVQPQVQPQAHSQ--PPRQVQLQLQKQ----VQTQTYPQVHTQAQPSVQPQ-------- 446
               Q +++P   SQ  P +Q Q+Q        +Q  T  Q+ +Q QP  QPQ        
Sbjct: 2474 ---QTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAV 2530

Query: 447  -EHPPAQVSVQPPEQTHEQ 464
             EH   + S+ P E+   Q
Sbjct: 2531 IEHLKQKKSMTPAEREENQ 2549



 Score = 61.6 bits (148), Expect = 3e-09
 Identities = 65/225 (28%), Positives = 93/225 (41%), Gaps = 23/225 (10%)

Query: 275  GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
            GQLQ+  Q    +  P Q     L+  A+    + RF    L   A   S T   + +T 
Sbjct: 2303 GQLQLIPQGVTVLPGPGQ----QLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTA 2358

Query: 335  TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ-----EAEPQK-QVQPQVQPQAHSQGP 388
                    +Q Q++ SP+  V Q K + P         EA+PQ  Q   Q QPQ   Q P
Sbjct: 2359 AGTG----EQRQSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSP 2414

Query: 389  RQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ-VQLQLQK-QVQTQTYPQVHTQAQPSVQPQ 446
             Q ++Q + E    VQ Q    +H     Q    Q  K QV  Q+ PQ + Q Q  V+ Q
Sbjct: 2415 AQPEVQTQPE----VQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQ 2470

Query: 447  EHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP 491
               P+Q  ++P   +   P  Q QV     +  P+  H   L++P
Sbjct: 2471 S--PSQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHT-SLQIP 2512



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 68/242 (28%), Positives = 100/242 (41%), Gaps = 33/242 (13%)

Query: 153  QATRQSLLGPPPVGVPMNPSQFNLSGRNP----QKQARTSSSTTPNRKDSSSQTMPVEDK 208
            Q T Q  L P  V V   P Q  +    P    Q+   T  +TT     +++ T+     
Sbjct: 2300 QTTGQLQLIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTPLATTATTASTTTTTVSTT-A 2358

Query: 209  SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEP 268
            +   E  +    P+M   +D+ LPP                 P EA    A+     +  
Sbjct: 2359 AGTGEQRQSKLSPQMQVHQDKTLPPAQSSSVG----------PAEAQPQTAQPSAQPQPQ 2408

Query: 269  TEKEPPGQLQVKAQPQARMTVPKQTQTPD----LLPEALEAQVLPRFQPRVLQVQAQ--- 321
            T+ + P Q +V+ QP+ +      +  P        ++ + QV  + QP+   VQ Q   
Sbjct: 2409 TQPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQ-SNVQGQSPV 2467

Query: 322  -VQSQTQPRI-PSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQP--QLQQEAEPQKQVQP 377
             VQS +Q RI PST +Q+ P  Q Q QT TS      Q   +QP   LQ  ++ Q Q QP
Sbjct: 2468 RVQSPSQTRIRPSTPSQLSPGQQSQVQTTTS------QPIPIQPHTSLQIPSQGQPQSQP 2521

Query: 378  QV 379
            QV
Sbjct: 2522 QV 2523



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 135/693 (19%), Positives = 231/693 (33%), Gaps = 118/693 (17%)

Query: 164  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRM 223
            P+GVP  P +       PQ++   SS+  P R ++  QT PV  ++   E   E  E R 
Sbjct: 1970 PIGVPETPKETP----TPQRKGLRSSALRPKRPETPKQTGPVIIETWVAEEELELWEIRA 2025

Query: 224  DTPE-DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQ 282
                 +++     E  AK++           ++  P     S+  P +K     +     
Sbjct: 2026 FAERVEKEKAQAVEQQAKKRLEQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPISGSVT 2085

Query: 283  PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQA-----QVQSQTQPRIPS----- 332
               +M +  +  +P  +           F   V Q Q+     QVQ +    IPS     
Sbjct: 2086 TGTKMVLTTKVGSPATVTFQQNKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIPSSTGTS 2145

Query: 333  --TDTQVQPKL-------QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ--------- 374
              T T  QP+               T+    V+   Q++P +     P +Q         
Sbjct: 2146 QQTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIR 2205

Query: 375  ----VQPQVQPQAHSQ------------GPRQVQLQQEAEPLKQVQPQVQPQAH-SQPPR 417
                VQP    Q  +Q             P  V      + L         Q+  SQPPR
Sbjct: 2206 TPVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKSLTSATSTSNIQSSASQPPR 2265

Query: 418  QVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ---VSVQPPEQTHEQPHTQPQVSLL 474
              Q Q++            T AQ +   Q H   Q   V +Q   QT  Q    PQ   +
Sbjct: 2266 PQQGQVKL-----------TMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVTV 2314

Query: 475  APEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENR 534
             P     ++          A    G +++ L  P+ T  +       +      G  E R
Sbjct: 2315 LPGPGQQLM---------QAAMPNGTVQRFLFTPLATTATTASTTTTTVSTTAAGTGEQR 2365

Query: 535  AREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA---L 591
              ++           +   QSS        P T  P       + P + + P  Q    +
Sbjct: 2366 QSKLSPQMQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQSPAQPEVQTQPEV 2425

Query: 592  QFFCYICKASCSSQQEFQDHMSEPQ---HQQRLGEIQHMSQACLLS-------------L 635
            Q    +     S  Q      S+PQ     Q    +Q  S   + S             L
Sbjct: 2426 QTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPSTPSQL 2485

Query: 636  LPVPRDVLETEDEEPPPRRWCNTCQLYYMGD-------LIQHRRTQDHKIAKQSLRPF-- 686
             P  +  ++T   +P P +   + Q+   G        +++H    +H   K+S+ P   
Sbjct: 2486 SPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLKQKKSMTPAER 2545

Query: 687  -----CTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAGQDEDHFITVDAVGCFE 741
                   VCN+  K     ++  + Q  K + +E +S+E++ + Q+      +     F+
Sbjct: 2546 EENQRMIVCNQVMKYILDKIDKEEKQAAKKRKRE-ESVEQKRSKQNATKLSAL----LFK 2600

Query: 742  GDEEEEEDD-------EDEEEIEVEEELCKQVR 767
              E+   +        + + +IEV+EEL + ++
Sbjct: 2601 HKEQLRAEILKKRALLDKDLQIEVQEELKRDLK 2633



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 16/53 (30%), Positives = 29/53 (54%), Gaps = 9/53 (16%)

Query: 709 HKDKAKELKSLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDEEEIEVEEE 761
           + D   E +  E+++  ++E+           +GD EE +D ED+EE E+EE+
Sbjct: 126 YDDHESEEEEEEEDMVSEEEEEE---------DGDAEETQDSEDDEEDEMEED 169


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
           sapiens]
          Length = 1362

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 77/309 (24%), Positives = 120/309 (38%), Gaps = 30/309 (9%)

Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP-PC 234
           + G +  +   +S S++ + +DS ++  P   K   P G E+         + Q  P P 
Sbjct: 695 MKGFSSSESESSSESSSSDSEDSETEMAPKSKKKGHP-GREQKKHHHHHHQQMQQAPAPV 753

Query: 235 PEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK--Q 292
           P+      + P P P P           +  ++P    PP  +  +A P  + + P    
Sbjct: 754 PQQPPPPPQQPPPPPPP-----------QQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIA 802

Query: 293 TQTPDLLPEALEAQVLP--RFQPRVLQVQAQVQSQTQPRIPST-DTQVQPKLQKQAQTQT 349
           TQ P L P+   +   P   F   +L +    Q +  P +P   +    P L + A    
Sbjct: 803 TQVPVLEPQLPGSVFDPIGHFTQPILHLP---QPELPPHLPQPPEHSTPPHLNQHAVVSP 859

Query: 350 SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQP 409
              H  L Q+  +P  +  A P K  +P     A +Q P   Q    A+P + +    +P
Sbjct: 860 PALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPM-AQPPQVLLEDEEP 918

Query: 410 QAHSQPPRQVQLQLQK----QVQTQTYPQVHTQAQ--PSVQPQEHPPA--QVSVQPPEQT 461
            A      Q+QL LQ+    Q  T   P V  Q+Q  P + P  HP    Q+  QPP   
Sbjct: 919 PAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPP 978

Query: 462 HEQPHTQPQ 470
             QP   PQ
Sbjct: 979 PPQPQPPPQ 987



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 86/356 (24%), Positives = 119/356 (33%), Gaps = 38/356 (10%)

Query: 134  APSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTP 193
            AP+  P Q   P  Q   P   +Q    PPP   P  PS        PQ+ A    S+ P
Sbjct: 749  APAPVPQQPPPPPQQPPPPPPPQQQQQPPPP---PPPPSM-------PQQAAPAMKSSPP 798

Query: 194  NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP------AP 247
                +    +  +      +      +P +  P+ +  P  P+    E  TP      A 
Sbjct: 799  PFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQP--PEHSTPPHLNQHAV 856

Query: 248  EPEPCEASELPAKRLRSSEEPTEKEP---------PGQLQVKAQPQARMTVPKQTQTPDL 298
               P   + LP +  R S       P         P   Q    PQ  M  P Q    D 
Sbjct: 857  VSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDE 916

Query: 299  LPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
             P A     L   Q ++   Q Q      P +PS   Q QP          S +  + QQ
Sbjct: 917  EPPA---PPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQ 973

Query: 359  KQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
                P  Q +  PQ+Q QP  +P  H Q P Q     +  P  Q Q    P    QPP  
Sbjct: 974  PPPPPPPQPQPPPQQQHQPPPRP-VHLQ-PMQFSTHIQQPPPPQGQQPPHPPPGQQPPPP 1031

Query: 419  VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ------THEQPHTQ 468
               + Q+ +Q    P+ H     S       P+ + +  P+       TH+ P  Q
Sbjct: 1032 QPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ 1087



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 114/473 (24%), Positives = 162/473 (34%), Gaps = 112/473 (23%)

Query: 26   QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQ-----PLLNLQGTNSASLL 80
            +Q++       Q+QQ     P Q P P       PP Q QQ     P        +A  +
Sbjct: 734  EQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQQAAPAM 793

Query: 81   NGSMLQRALLLQQLQGLDQFAMPPATYDTAG-LTMPTATLGNLRGYGMASPGLAAPSLTP 139
              S      +  Q+  L+   +P + +D  G  T P   L          P L      P
Sbjct: 794  KSS--PPPFIATQVPVLEP-QLPGSVFDPIGHFTQPILHL--------PQPELPPHLPQP 842

Query: 140  PQLATPNLQQFFPQATRQSLLGPPPV--GVPMNPSQ-FNLSGRNPQKQARTSSSTTPNRK 196
            P+ +TP      P   + +++ PP +   +P  PS+  N +   P K AR      P   
Sbjct: 843  PEHSTP------PHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPAR-----PPAVS 891

Query: 197  DSSSQT--MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEA 254
             + +QT  +P    + PP+   E  EP                       PAP P     
Sbjct: 892  PALTQTPLLPQPPMAQPPQVLLEDEEP-----------------------PAP-PLTSMQ 927

Query: 255  SELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPR 314
             +L  ++L+  + PT   P              +V  Q+Q P  LP            P 
Sbjct: 928  MQLYLQQLQKVQPPTPLLP--------------SVKVQSQPPPPLP-----------PPP 962

Query: 315  VLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ 374
               VQ Q+Q Q  P  P    Q QP  Q+Q Q    P H  LQ  Q    +QQ   PQ Q
Sbjct: 963  HPSVQQQLQQQPPPPPP---PQPQPPPQQQHQPPPRPVH--LQPMQFSTHIQQPPPPQGQ 1017

Query: 375  VQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQ 434
              P   P      P      Q A+P + +Q    P+ H   P               Y  
Sbjct: 1018 QPPHPPPGQQPPPP------QPAKPQQVIQHHHSPRHHKSDP---------------YST 1056

Query: 435  VHTQAQPSV----QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVV 483
             H +  PS      PQ      ++ Q P Q + QP  Q   +    +  P+VV
Sbjct: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVV 1109



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 98/439 (22%), Positives = 142/439 (32%), Gaps = 63/439 (14%)

Query: 5    QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
            QQ Q++Q     L  ++ Q      L       +QQ LQQ PP  P P       PPQQ 
Sbjct: 933  QQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQP---PPQQQ 989

Query: 65   QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
             QP                   R + LQ +Q       PP          P        G
Sbjct: 990  HQP-----------------PPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPP-------G 1025

Query: 125  YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGV-PMNPSQFNLSGRNPQK 183
                 P  A P        +P   +  P +T      P P+ +     SQF         
Sbjct: 1026 QQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPP 1085

Query: 184  QARTSSSTTPNRKDSSSQTMPV----EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIA 239
            Q          R  S  Q  P+    E+K   P    E   P +  PE    P  PE I 
Sbjct: 1086 QQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSL-RPEP---PKHPESIK 1141

Query: 240  KEKRTP-APEPEPCEASE--------------LPAKRLRSSEEPTEKEPPGQLQVKAQPQ 284
                 P  PE +P +                  P K  +  E  T   P   L++K    
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPKKDLKIKNMGS 1201

Query: 285  ARMTVPKQTQTP--------DLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
                V K   TP        D   +   A      + + L+ QA+   + + R+     +
Sbjct: 1202 WASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMR 1261

Query: 337  VQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQ----VQPQVQPQAHSQGPRQVQ 392
             +       Q + + E    +Q+Q Q Q Q++ + Q+Q    V     PQA S  P+ + 
Sbjct: 1262 SREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSML 1321

Query: 393  LQQEAEPLKQVQPQVQPQA 411
             QQ     K+ Q + + +A
Sbjct: 1322 DQQRELARKREQERRRREA 1340



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 43/178 (24%), Positives = 62/178 (34%), Gaps = 16/178 (8%)

Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
           LQK  +  T    +++ Q + + + ++E    K     V     +  P Q Q  Q   P 
Sbjct: 158 LQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPP 217

Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ 460
            Q  P      H  P     L +Q  V T   PQ   Q  P V PQ  PP   + QP + 
Sbjct: 218 VQATP------HPFPAVTPDLIVQTPVMTVVPPQP-LQTPPPVPPQPQPPPAPAPQPVQS 270

Query: 461 -------THEQPHTQPQVSLLAPEQTPVVVHVC--GLEMPPDAVEAGGGMEKTLPEPV 509
                  T +   T+  V   A   TP  +        +PP+      G  +    PV
Sbjct: 271 HPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPV 328



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 18/41 (43%), Positives = 23/41 (56%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ 44
            Q+QQQQ +Q+QQQ QQ Q   +      Q Q  Q Q +L Q
Sbjct: 1283 QEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQ 1323



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 40/179 (22%), Positives = 66/179 (36%), Gaps = 21/179 (11%)

Query: 178 GRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSE-----EAAEPRM--DTPEDQD 230
           GR     A+   ST PN   +S+       + +PP          A  P +   TP    
Sbjct: 182 GRKETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTV 241

Query: 231 LPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVP 290
           +PP P       +TP P P   +    PA +   S  P     P  ++ K   + +    
Sbjct: 242 VPPQP------LQTPPPVPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRK---- 291

Query: 291 KQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS---TDTQVQPKLQKQAQ 346
             T TP  +    E   LP  +P+  ++  + +S    + P     D+Q  P  +K ++
Sbjct: 292 ADTTTPTTIDPIHEPPSLPP-EPKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSK 349


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 79/359 (22%), Positives = 150/359 (41%), Gaps = 43/359 (11%)

Query: 181   PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
             P+K         P  K   +    V +    PE       P+ + P    +P  P+    
Sbjct: 9954  PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVP 10013

Query: 241   EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 299
             E++ P P P+  EA       +     P +K P P   +V+A P     VPK+     L+
Sbjct: 10014 EEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKK-----LI 10068

Query: 300   PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA-QTQTSPEHLVL-Q 357
             PE  +   +P+      +V+A      + R P       P+ ++   + +  PE  VL +
Sbjct: 10069 PEEKKPTPVPK------KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPE 10122

Query: 358   QKQVQPQLQQEAEPQKQVQP---QVQPQAHSQGPRQVQLQQEAE--PLKQVQPQVQPQAH 412
             +++V P+ ++    +++V P   ++ P+     P +  + +E E  P ++V P+V+P+  
Sbjct: 10123 EEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVP 10182

Query: 413   SQPP----------RQVQLQLQKQVQTQTYPQVHTQAQPS--VQPQEHP--PAQVSVQP- 457
                P          ++V +  +++      P+V  + +    + P+E    P +V+ +P 
Sbjct: 10183 VPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPE 10242

Query: 458   -----PEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMP---PDAVEA-GGGMEKTLPE 507
                   E+  E+P +  +V  +AP + P V+     E P   P  VEA    + K +PE
Sbjct: 10243 EEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 85/390 (21%), Positives = 142/390 (36%), Gaps = 65/390 (16%)

Query: 130   PGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGR---------- 179
             P    P + PP+   P  +   P A +      PP  VP  P +     +          
Sbjct: 10491 PPTKVPEVLPPKEVVPEKKVPVPPAKKPEA---PPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 180   -NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEE-----------AAEPRMDTPE 227
               P K      +  P +K    + +P + +S PPE  E            AA P+     
Sbjct: 10548 VPPTKVPEVPKAAVPEKK--VPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVT 10605

Query: 228   DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARM 287
                +P  P+++  EK+ P P P+  E        +     P +K P              
Sbjct: 10606 PVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPE------------- 10652

Query: 288   TVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQT 347
              +P + ++P   PE  E       +    +V  + +    P++     +  P+ +  A  
Sbjct: 10653 AIPPKPESPP--PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVV 10710

Query: 348   QTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQV-QLQQEAEPLKQVQPQ 406
                PE   L   +V P++ +E  P+K+V P V P+     P +V ++ +E  P K+V   
Sbjct: 10711 AKKPE---LPPVKV-PEVPKEVVPEKKV-PLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 407   VQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
              +P+    PP +V             P+V  +     +P    P +    PPE   E   
Sbjct: 10766 KKPEV---PPAKV-------------PEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEE 10809

Query: 467   TQPQVSLLAPEQTPV-VVHVCGLEMPPDAV 495
               P+  +   E+ PV V      E+PP AV
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPAV 10839



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 66/266 (24%), Positives = 110/266 (41%), Gaps = 27/266 (10%)

Query: 246   APEPEPCEASELPAKRLRSSEEPTE-KEPPGQLQVKAQPQARMT-VPKQTQTPDLLPEAL 303
             A E E  E  + P K    SE+    K+PP ++  + +P A++  VPK+    + +    
Sbjct: 10427 AEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE 10486

Query: 304   EAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV----LQQK 359
             E +V P   P VL  +  V  +  P  P+   +  P    +A  +  PE  V     ++ 
Sbjct: 10487 EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKP 10546

Query: 360   QVQ----PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV------QPQVQP 409
             +V     P++ + A P+K+V   + P+  S  P   +  +E  P K+V      +P+V P
Sbjct: 10547 EVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606

Query: 410   QAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQP 469
                 + P++V  + +  V     P+V     P V     P  +V    PE    +P + P
Sbjct: 10607 VKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKV----PEAIPPKPESPP 10662

Query: 470   QVSLLAPEQTPVVVHVCGLEMPPDAV 495
                   PE+         LE PP  V
Sbjct: 10663 PEVFEEPEEV-------ALEEPPAEV 10681



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 71/360 (19%), Positives = 138/360 (38%), Gaps = 62/360 (17%)

Query: 181   PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
             P+K         P ++      +P   K   PE       P+        +P  P+    
Sbjct: 9982  PKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVP 10041

Query: 241   EKRTPAPEPE-----PCEASELPAKRLRSSEEPTE-----KEPPGQLQVKAQPQA----- 285
             EK+ P P P+     P +  E+P K +   ++PT      + PP ++  K +P       
Sbjct: 10042 EKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVAL 10101

Query: 286   ---------RMTVPKQTQTPD---LLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPST 333
                         VP++   P+   +LPE  E +VLP  +  VL  + ++  + +   P  
Sbjct: 10102 PQEEEVLFEEEIVPEEEVLPEEEEVLPE--EEEVLPE-EEEVLPEEEEIPPEEEEVPPEE 10158

Query: 334   D---------------TQVQPKLQKQA-----QTQTSPEHLVLQQKQVQPQLQQEAEPQK 373
             +                +V+PK+   A     + + + + +V+ +K+  P  +    P+K
Sbjct: 10159 EYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKK 10218

Query: 374   QVQPQV-QPQAHSQGPRQVQLQQEAEPLKQVQ-----PQVQPQAHSQPPRQVQLQLQKQV 427
               + ++  P+     P +V  + E EP+ + +     P ++      PPR  ++  +   
Sbjct: 10219 VEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVP 10278

Query: 428   QTQTYPQVHTQAQPSVQPQEHP------PAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPV 481
             +  T      +A P+   ++ P      P Q    PP +  E P   P+  +L P++  V
Sbjct: 10279 EAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 86/411 (20%), Positives = 161/411 (39%), Gaps = 52/411 (12%)

Query: 129   SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGP-----PPVGVPMNPSQFNLSGRNPQK 183
             +P + A     P +  P + +      +  L+ P     PP  VP  P +       P+K
Sbjct: 10706 APAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-----PEK 10760

Query: 184   Q-ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
             + A       P  K       PV ++       E A  P  +  E+ +     E+IA E+
Sbjct: 10761 KVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEE 10820

Query: 243   RTPAP-----EPE--PCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQT 295
               P P     EPE  P    E P K +   + P  K+P      + +P+  +  PK    
Sbjct: 10821 EKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPR 10880

Query: 296   PDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLV 355
             P   P A   + +   + ++ Q++A         IP    +V  K Q   + + +P  + 
Sbjct: 10881 PPPPPPAPPKEDV---KEKIFQLKA---------IPK--KKVPEKPQVPEKVELTPLKVP 10926

Query: 356   LQQKQVQPQL-QQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQ 414
               +K+V+  L +++ EP+++V   V      + P + + + E + L++V+    P+    
Sbjct: 10927 GGEKKVRKLLPERKPEPKEEV---VLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPE--PP 10981

Query: 415   PPRQVQ-------LQLQKQVQTQT-YPQVHTQAQ-PSVQPQEHPPAQVSVQPPEQTHEQP 465
             PP+ V+        + ++++   T  P++      P+ +P+  P A+V    P     +P
Sbjct: 10982 PPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEP 11041

Query: 466   HTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSME 516
                    + AP   PVV      + P +      G  K +P+   + +  E
Sbjct: 11042 -----TPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAE 11087



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 72/355 (20%), Positives = 142/355 (40%), Gaps = 46/355 (12%)

Query: 203  MPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPE----PCEASELP 258
            +P+  K +PP   +    P+   PE++   P P+   KE   P   PE    P    ++P
Sbjct: 9303 VPIPKKVEPP-APKVPEVPKKPVPEEKKPVPVPK---KEPAAPPKVPEVPKKPVPEEKIP 9358

Query: 259  AKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQV------LPRFQ 312
                +  E P  K P  Q  V  + +  +   ++   P  +PE  + +V      +PR +
Sbjct: 9359 VPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKE 9418

Query: 313  PRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQA---QTQTSPEHLVLQQKQVQPQLQQEA 369
              V     +V +  +  +P     V   + K+A   + + S + +V +++ V  +    A
Sbjct: 9419 EEV-PPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFA 9477

Query: 370  EPQKQVQPQVQPQAHSQGPR-------QVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
             PQ+    + +  A  +           + + +E E  ++ + +V      + P +  ++
Sbjct: 9478 VPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVE 9537

Query: 423  -----LQKQVQTQTYPQVHTQAQPSV-------QPQEHPPAQVSVQPPEQTHEQ--PHTQ 468
                 + K+V+ +       Q +  V       + +E PPA+V   P +   E+  P   
Sbjct: 9538 EKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPV 9597

Query: 469  PQVSLLAPEQTPVVVH--VCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNE 521
            P+   + P + P      V   ++PP  ++    ME+ LP  V T+  M+  Q E
Sbjct: 9598 PKKEKVPPPKVPEEPKKPVPEKKVPPKVIK----MEEPLPAKV-TERHMQITQEE 9647



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 78/369 (21%), Positives = 147/369 (39%), Gaps = 61/369 (16%)

Query: 203   MPVEDKSDPPEGSEEAAEP----RMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELP 258
             +PV+   + P  ++  A P    +   PE++   P P+     K  P P   P E  ++ 
Sbjct: 9793  IPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPK-----KLKPPPPKVPEEPKKVF 9847

Query: 259   AKRLRSSEEPTEKE----PPGQLQVKAQ---PQARMTVPKQTQTP---------DLLPE- 301
              +++R S    EKE    P  ++ +K +    + ++ VP++   P         +L PE 
Sbjct: 9848  EEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEE 9907

Query: 302   -ALEAQVLPRFQPRVLQVQAQ---------VQSQTQPRIPSTDTQVQPK----------- 340
              A E +V+   +  +++ + +          + +  P IP    +V  K           
Sbjct: 9908  VAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPV 9967

Query: 341   -LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQV--QPQAHSQGPRQVQLQQEA 397
               +K+A     PE     +++V   + ++ +P     P+V  +P    + P  V  + EA
Sbjct: 9968  PKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEA 10027

Query: 398   EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQT--YPQVHTQAQPSVQPQEHPPAQVSV 455
              P K  +   +P     P ++V +   K+V+      P+V  +  P  +     P +V  
Sbjct: 10028 PPAKVPEVPKKPV----PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEA 10083

Query: 456   QPPEQTHEQPHTQPQVSLLAPEQTPVVVH---VCGLEMPPDAVEAGGGMEKTLPEPVGTQ 512
              PP+   ++      V+L  P++  V+     V   E+ P+  E     E+ LPE     
Sbjct: 10084 PPPKVPKKREPVPVPVAL--PQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL 10141

Query: 513   VSMEEIQNE 521
                EEI  E
Sbjct: 10142 PEEEEIPPE 10150



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 119/608 (19%), Positives = 227/608 (37%), Gaps = 86/608 (14%)

Query: 192  TPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDL--PPCPEDIAKEKRTPAPEP 249
            TP  K    + + V  K+   +  +  A+P+  TP ++ +  PP P  +      PA  P
Sbjct: 8971 TPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTL-----IPAKAP 9025

Query: 250  E----PCEASELPAKRL-RSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALE 304
            E      +A E+    + R  E   EKE   + +     + R+ +    +  D      E
Sbjct: 9026 EIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYD------E 9079

Query: 305  AQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQ---KQAQTQTSPEHLVLQQKQV 361
             +V P  +P       +     +        +V  + +   ++ Q     E    + ++ 
Sbjct: 9080 LEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE 9139

Query: 362  QPQLQQEAEPQKQVQPQVQPQAHSQG-PRQVQLQQEAEPLKQVQ----PQVQPQAHSQPP 416
              +  QE E   QVQ +V  ++H +  P +V  ++   P K ++     +++  +     
Sbjct: 9140 WEEAYQERE-VIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEE 9198

Query: 417  RQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQ---------PPEQTHEQPHT 467
             +VQ+    +V  +  PQ     +PS  P +    +V V            E+     HT
Sbjct: 9199 EKVQVTKVPEVSKKIVPQ-----KPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHT 9253

Query: 468  QPQVSLLAPE-QTPVV----VHVC---GLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQ 519
            + +VS+  PE Q  +V    +HV     +E PP   E     EK  PE V      ++++
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPEL---PEKPAPEEVAPVPIPKKVE 9310

Query: 520  NESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSST 579
              +    +V +      + P        + V   + +       VP  PVP     V   
Sbjct: 9311 PPAPKVPEVPKKPVPEEKKP--------VPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVA 9362

Query: 580  PAATSTPSK--QALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLP 637
                + P+K  +  +      K +  +Q+E     + P+  ++    +           P
Sbjct: 9363 KKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERK---------P 9413

Query: 638  VPRDVLETEDEEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTP 697
            VPR     E+E PPP +            + + +      +AK++  P   V  +     
Sbjct: 9414 VPR----KEEEVPPPPK----VPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEE 9465

Query: 698  RKFVEHVKSQGHKDKAKELK----SLEKEIAGQDEDHFITVDAVGCFEGDEEEEEDDEDE 753
            ++FV   K      +  E+     S E+E +  +E+  +++     +  +E EEE++ + 
Sbjct: 9466 KRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISV---YREEEREEEEEAEV 9522

Query: 754  EEIEVEEE 761
             E EV EE
Sbjct: 9523 TEYEVMEE 9530



 Score = 38.1 bits (87), Expect = 0.037
 Identities = 61/316 (19%), Positives = 117/316 (37%), Gaps = 54/316 (17%)

Query: 137   LTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNP---QKQARTSSSTTP 193
             + P +   P  ++  P A  +    PPP  VP  P +     + P   + +A       P
Sbjct: 10810 IAPEEEIAPEEEKPVPVAEEEEPEVPPPA-VPEEPKKIIPEKKVPVIKKPEAPPPKEPEP 10868

Query: 194   NRKDSSSQTMPVEDKSDPPEGSEEAAE--------PRMDTPEDQDLPPCPE--------- 236
              +     +  P      P    E+  E        P+   PE   +P   E         
Sbjct: 10869 EKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928

Query: 237   DIAKEKRTPAPEPEPCEASELPA---------------KRLRSSEEPTEKEPPG-----Q 276
             +    K  P  +PEP E   L +               K+L   ++P   EPP      +
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988

Query: 277   LQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQ 336
             ++V    +    +P+ T+ P++ P    A  LP  +P+  + +A+V++   P +    T 
Sbjct: 10989 VEVPTVTKRERKIPEPTKVPEIKP----AIPLPAPEPKP-KPEAEVKTIKPPPVEPEPTP 11043

Query: 337   VQ-----PKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGP--- 388
             +      P + K+A+ +   E     +  ++   ++   P +  + +++P +  + P   
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDE 11103

Query: 389   RQVQLQQEAEPLKQVQ 404
                  Q +A PLK V+
Sbjct: 11104 APFTYQLKAVPLKFVK 11119



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 60/320 (18%), Positives = 118/320 (36%), Gaps = 45/320 (14%)

Query: 196 KDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEAS 255
           K + ++ +   DK+   E      E  + T + + +    E I KE            A+
Sbjct: 473 KTAVTKVVVAADKAKEQELKSRTKE--VITTKQEQMHVTHEQIRKETEKTFVPKVVISAA 530

Query: 256 ELPAKRLRSSEEPTEKEPP-------GQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
           +   +  R SEE T+K+          + ++ A     +   K T+  + +P A E    
Sbjct: 531 KAKEQETRISEEITKKQKQVTQEAIRQETEITAASMVVVATAKSTKL-ETVPGAQEETTT 589

Query: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ---PQL 365
            + Q  +     ++  +T+  +        PK+++Q       E +  +++QVQ    ++
Sbjct: 590 QQDQMHLSY--EKIMKETRKTVVPKVIVATPKVKEQDLVSRGREGITTKREQVQITQEKM 647

Query: 366 QQEAEP-----------QKQVQPQVQPQAHSQGPRQVQLQ---------QEAEPLKQVQP 405
           ++EAE            + + Q  +     +   RQ Q+Q         ++AE +  V  
Sbjct: 648 RKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVTHGKVDVGKKAEAVATVVA 707

Query: 406 QVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQP 465
            V  QA  + PR+     +   Q  T    +         +E   A    +PP++   +P
Sbjct: 708 AVD-QARVREPREPGHLEESYAQQTTLEYGY---------KERISAAKVAEPPQRPASEP 757

Query: 466 HTQPQVSLLAPEQTPVVVHV 485
           H  P+       Q P   H+
Sbjct: 758 HVVPKAVKPRVIQAPSETHI 777


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 109/464 (23%), Positives = 172/464 (37%), Gaps = 56/464 (12%)

Query: 13  QQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQ 72
           ++Q L QLQQ Q Q  Q Q Q +LQ   L    PP  P P+    G    QP  P +   
Sbjct: 54  REQHLAQLQQLQ-QMHQKQMQCVLQPHHL--PPPPLPPPPVMPGGGYGDWQPPPPPMPPP 110

Query: 73  GTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGL 132
              + S       +  +L  Q  G      PP                 L    + SP  
Sbjct: 111 PGPALSYQKQQQYKHQMLHHQRDG------PPG----------------LVPMELESPPE 148

Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
           + P   PP    P  Q + P         PP    P  P       ++P  Q+  + + +
Sbjct: 149 SPP--VPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAPTPS 206

Query: 193 PNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPC 252
            +   SSSQ+     +S  P      + P     + Q L P P       +T   + EP 
Sbjct: 207 YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPGNKTTV-QQEPL 265

Query: 253 EASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQ---ARMTVPKQTQTPDLLPEALEAQVL 308
           E+    AK   + ++    EP P  +  + Q Q    +  +  Q +T   LP   +  V+
Sbjct: 266 ESG---AKNKSTEQQQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGPVV 322

Query: 309 PRFQPRVLQVQAQVQSQTQ-PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
            +  P  ++ +  V + +Q P  PS++    P   ++      PE    +  +   +L+Q
Sbjct: 323 AKDTPEPVKEEVTVPATSQVPESPSSEEPPLPPPNEEVPPPLPPEEPQSEDPEEDARLKQ 382

Query: 368 ----EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQL 423
                A  Q+  Q +V  Q      +  QLQQ    L+Q Q  +QP  H Q    V +QL
Sbjct: 383 LQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQ---ILQQYQQIIQPPPHIQ-TMSVDMQL 438

Query: 424 QK-QVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPH 466
           +  ++Q Q +  ++ + +   Q  E           EQ H  PH
Sbjct: 439 RHYEMQQQQFQHLYQEWEREFQLWE-----------EQLHSYPH 471



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 77/312 (24%), Positives = 104/312 (33%), Gaps = 58/312 (18%)

Query: 11  QQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVS---RGLPPQQPQQP 67
           QQ QQ     Q Q + Q+  Q QQ+LQ  Q + Q PP     M+V    R    QQ Q  
Sbjct: 391 QQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQPPPHIQ-TMSVDMQLRHYEMQQQQFQ 449

Query: 68  LLNLQGTNSASL-----------------------LNGSMLQRALLLQQL---------Q 95
            L  +      L                         G M      LQ+          Q
Sbjct: 450 HLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQ 509

Query: 96  GLDQFAMPPATYDTAGL-----TMPTATLGNLRGYGMASPGLAA---PSLTPPQLATPNL 147
            +   +MPP     + +     TMP   L       +  P L A   P   PP +  P+L
Sbjct: 510 YMGNMSMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSL 569

Query: 148 QQFFP---QATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
               P        S  GPPPV   + P   + +G  P     + SST P         +P
Sbjct: 570 PTSVPPPGMPPSLSSAGPPPV---LPPPSLSSAGPPPVLPPPSLSSTAP----PPVMPLP 622

Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
               + PP G      P+   P+    P  P   ++  + P  +P P   + LP      
Sbjct: 623 PLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVP-EKPRP---ALLPTPVSFG 678

Query: 265 SEEPTEKEPPGQ 276
           S  PT   PP Q
Sbjct: 679 SAPPTTYHPPLQ 690



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 102/498 (20%), Positives = 173/498 (34%), Gaps = 64/498 (12%)

Query: 1   MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQ--SPPQAPLPMAVSRG 58
           + S   + QLQ+ ++Q +  Q      Q   Q+++   Q +  Q       P P      
Sbjct: 466 LHSYPHKDQLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQ 525

Query: 59  LPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTAT 118
           +PP  P  P   L  +    ++  ++           G+    MPP+        +PT+ 
Sbjct: 526 MPPPLPTMPPPVLPPSLPPPVMPPALPATV----PPPGMPPPVMPPS--------LPTSV 573

Query: 119 LGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSG 178
                   ++S G   P L PP L++       P  +  S   PP + +P   S     G
Sbjct: 574 PPPGMPPSLSSAG-PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 179 RNP---QKQARTSSSTTPNRKDSSSQTMPVEDKSD----PPEGSEEAAEPRMDTPEDQDL 231
             P    +      +  P    SSSQ+  V +K      P   S  +A P    P  Q  
Sbjct: 633 IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSA 692

Query: 232 PPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPK 291
            P  +  +K          P   S LP     S +        G  +  A P   +T  K
Sbjct: 693 GPSEQVNSK---------APLSKSALPYSSFSSDQ--------GLGESSAAPSQPITAVK 735

Query: 292 Q--TQTPDLLPEA-----LEAQVLPRFQ-PRVLQVQAQVQSQTQPRIPSTDTQ----VQP 339
               ++  LLP+      LE+   PRF  PR  +         +P+ P  +       +P
Sbjct: 736 DMPVRSGGLLPDPPRSSYLESPRGPRFDGPRRFEDLGSRCEGPRPKGPRFEGNRPDGPRP 795

Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ-EAE 398
           + +      T  +  ++ +    P  Q    P   + P+ Q     +GP+    QQ + +
Sbjct: 796 RYEGHPAEGTKSKWGMIPR---GPASQFYITPSTSLSPR-QSGPQWKGPKPAFGQQHQQQ 851

Query: 399 PLKQVQP---QVQPQAHSQPPRQVQLQLQK-----QVQTQTYPQVHTQAQPSVQPQEHPP 450
           P  Q +P     +P A +   +Q   ++Q          +      +    S   QE P 
Sbjct: 852 PKSQAEPLSGNKEPLADTSSNQQKNFKMQSAAFSIAADVKDVKAAQSNENLSDSQQEPPK 911

Query: 451 AQVSVQPPEQTHEQPHTQ 468
           ++VS  P E ++   + Q
Sbjct: 912 SEVSEGPVEPSNWDQNVQ 929


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 111/485 (22%), Positives = 167/485 (34%), Gaps = 70/485 (14%)

Query: 5    QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
            +Q+ + QQ Q +LQQ Q  + +   +Q+  ++  QQ L    P  P      +   PQ P
Sbjct: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869

Query: 65   QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
            Q                           Q Q     +MPP              L   + 
Sbjct: 1870 QP------------------------TSQPQPTPPNSMPP-------------YLPRTQA 1892

Query: 125  YGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQ 184
             G  S G AA  +TPP   TP      PQ  +  L GPPP  V M   Q   +    ++ 
Sbjct: 1893 AGPVSQGKAAGQVTPP---TP------PQTAQPPLPGPPPAAVEM-AMQIQRAAETQRQM 1942

Query: 185  ARTSSSTTPNRKDSSSQTMPVEDKSDPP---EGSEEAAEPRMDTPEDQDLPPCPE-DIAK 240
            A       P +      T       +PP    G     EP M     Q  PP  +  + +
Sbjct: 1943 AHVQIFQRPIQHQMPPMTPMAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQ 2002

Query: 241  EKRTPAPEPEPCEASELPAKRLRSSEEPTEKEP-PGQLQVKAQPQARMTVPKQTQTPDLL 299
             ++  +  P P   S      +    +P    P PG  QV   P    TV +Q      L
Sbjct: 2003 PQQLQSGMPRPAMMS------VAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQAL--QNL 2054

Query: 300  PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK 359
               L +   P  Q +VL +         P++ +    ++ +  K A +   P        
Sbjct: 2055 LRTLRSPSSPLQQQQVLSI-----LHANPQLLA--AFIKQRAAKYANSNPQPIPGQPGMP 2107

Query: 360  QVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQV 419
            Q QP LQ    P +Q      P   +  P Q  +Q+   P +Q Q Q+QP      P+  
Sbjct: 2108 QGQPGLQPPTMPGQQ-GVHSNPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQ 2166

Query: 420  QLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
            Q+ +        +  +  + Q  +Q Q+   A   + P    H Q   QPQ     P+Q 
Sbjct: 2167 QMNMNHNTMPSQFRDI-LRRQQMMQQQQQQGAGPGIGPGMANHNQ-FQQPQGVGYPPQQQ 2224

Query: 480  PVVVH 484
              + H
Sbjct: 2225 QRMQH 2229



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 94/435 (21%), Positives = 165/435 (37%), Gaps = 61/435 (14%)

Query: 27   QQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQ 86
            Q++L++++  +LQ+          +P++++ G    QPQ  + +       S++ GS+  
Sbjct: 641  QKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQPQPGMTSNGPLPDPSMIRGSVPN 700

Query: 87   RAL-LLQQLQGLDQF-----AMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPP 140
            + +  +    GL+QF     A PP        T P    G L   G  +P    P    P
Sbjct: 701  QMMPRITPQSGLNQFGQMSMAQPPIV---PRQTPPLQHHGQLAQPGALNP----PMGYGP 753

Query: 141  QLATPNLQ-QFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTP------ 193
            ++  P+ Q QF PQ T+    G     +P+ PS    SG+ P  QA+ SSS+ P      
Sbjct: 754  RMQQPSNQGQFLPQ-TQFPSQGMNVTNIPLAPS----SGQAPVSQAQMSSSSCPVNSPIM 808

Query: 194  ---------------------NRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 232
                                 N         P    + P  G+++     +  P      
Sbjct: 809  PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPV----- 863

Query: 233  PCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
            P P  +    ++ A  P P +    P  +L    +P+    P   Q + QP+++ +    
Sbjct: 864  PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQQVQPSLPAAPSADQPQQQPRSQQSTAAS 923

Query: 293  TQTP--DLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTS 350
              TP   LLP        P  QP V  ++ QV +   P   ST+   Q   +KQ   +  
Sbjct: 924  VPTPTAPLLP---PQPATPLSQPAV-SIEGQVSN--PPSTSSTEVNSQAIAEKQPSQEVK 977

Query: 351  PEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ 410
             E   ++  Q +P   Q  +  +      + ++     R  +L+ E +  ++ QP     
Sbjct: 978  ME-AKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTELKTEIKE-EEDQPSTSAT 1035

Query: 411  AHSQPPRQVQLQLQK 425
              S  P Q + ++ K
Sbjct: 1036 QSSPAPGQSKKKIFK 1050



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 78/319 (24%), Positives = 103/319 (32%), Gaps = 40/319 (12%)

Query: 268  PTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQ 327
            P  ++P  Q Q   Q Q     P Q      +P A  +   P  Q ++      V S   
Sbjct: 753  PRMQQPSNQGQFLPQTQ----FPSQGMNVTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIM 808

Query: 328  PRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQK---QVQPQLQQEAEPQKQVQ-------- 376
            P          P+L + A  Q SP  +  +        P +  +  P   +         
Sbjct: 809  PPGSQGSHIHCPQLPQPALHQNSPSPVPSRTPTPHHTPPSIGAQQPPATTIPAPVPTPPA 868

Query: 377  --PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQ 434
              P  Q QA    PRQ        P  Q+  QVQP   + P    Q Q Q + Q  T   
Sbjct: 869  MPPGPQSQALHPPPRQT----PTPPTTQLPQQVQPSLPAAPSAD-QPQQQPRSQQSTAAS 923

Query: 435  VHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDA 494
            V T   P + PQ   PA    QP      Q    P  S      T V       + P   
Sbjct: 924  VPTPTAPLLPPQ---PATPLSQPAVSIEGQVSNPPSTS-----STEVNSQAIAEKQPSQE 975

Query: 495  VEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQ 554
            V+    ME   PEP  TQ           C ++  E E R+ E          LK  I +
Sbjct: 976  VKMEAKMEVDQPEPADTQPEDISESKVEDCKMESTETEERSTE----------LKTEIKE 1025

Query: 555  SSDSRAFSTVPLTPVPRPS 573
              D  + S    +P P  S
Sbjct: 1026 EEDQPSTSATQSSPAPGQS 1044



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 52/217 (23%), Positives = 78/217 (35%), Gaps = 44/217 (20%)

Query: 2    FSQQQQQQLQQQQQQLQQLQQQQLQQ------------QQLQQQQLLQLQQLLQQSPPQA 49
            +  QQQQ++Q   QQ+QQ    Q+ Q             Q  QQ+LLQ     Q   P  
Sbjct: 2219 YPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLLQ----QQMGSPVQ 2274

Query: 50   PLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDT 109
            P PM+  + + P Q Q P  +LQG    + L+                +Q   P      
Sbjct: 2275 PNPMSPQQHMLPNQAQSP--HLQGQQIPNSLS----------------NQVRSPQPVPSP 2316

Query: 110  AGLTMPTATLGNLRGYGMASPGLAAPSLTPPQ------LATPNLQQFFPQATRQSLLGPP 163
               + P  +  + R     SP   +P  + P        A P  Q  F    + S+L   
Sbjct: 2317 RPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQ- 2375

Query: 164  PVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSS 200
               +  NP   NL G +      ++ ++  N   S S
Sbjct: 2376 ---LASNPGMANLHGASATDLGLSTDNSDLNSNLSQS 2409



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 54/228 (23%), Positives = 84/228 (36%), Gaps = 40/228 (17%)

Query: 4    QQQQQQLQQ-------QQQQLQ--------QLQQQQLQQQQLQQQQLLQLQQLL---QQS 45
            QQ QQQLQ        Q QQ+         Q +    +QQ +QQQQ       +     +
Sbjct: 2148 QQPQQQLQPPMGGMSPQAQQMNMNHNTMPSQFRDILRRQQMMQQQQQQGAGPGIGPGMAN 2207

Query: 46   PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPA 105
              Q   P  V  G PPQQ Q+   ++Q     ++     L +AL  +    L  +     
Sbjct: 2208 HNQFQQPQGV--GYPPQQQQRMQHHMQQMQQGNMGQIGQLPQALGAEAGASLQAYQQRLL 2265

Query: 106  TYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQATRQSLLGPPP 164
                     P             +P      + P Q  +P+LQ Q  P +    +  P P
Sbjct: 2266 QQQMGSPVQP-------------NPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQP 2312

Query: 165  VGVPMNPSQFNLSGRNPQKQARTS------SSTTPNRKDSSSQTMPVE 206
            V  P   SQ   S  +P+ Q + S       +++P+    ++Q  P+E
Sbjct: 2313 VPSPRPQSQPPHSSPSPRMQPQPSPHHVSPQTSSPHPGLVAAQANPME 2360


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 77/376 (20%), Positives = 149/376 (39%), Gaps = 36/376 (9%)

Query: 181  PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAK 240
            P+ +   +       +++  QT P  +  +  E  EEA       PE +D+     ++  
Sbjct: 1933 PESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQ------PESEDVEALEVEVET 1986

Query: 241  EKRT--PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP-- 296
            ++      PE E  EA E   +   + EE   +    + Q K++ +    V  +TQ    
Sbjct: 1987 QEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEG 2046

Query: 297  DLLPEALEAQVLPRFQPRVLQVQAQVQS---QTQPRIPSTDTQVQPKLQKQAQTQTSPEH 353
            D  PE+ +    P  +    + + +VQ    +  P     D Q       +A+ +  PE 
Sbjct: 2047 DAQPES-DGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ-------EAEGEAQPES 2098

Query: 354  LVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEP------LKQVQPQV 407
              ++  + + + Q+ AE  +  + + + Q  S+G    + + EA+P       +  + + 
Sbjct: 2099 EGVEAPEAEGEAQK-AEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEA 2157

Query: 408  QPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHT 467
            QP++     ++ + + Q +++    P+   +AQP  +  E P A+   QP  +  E P  
Sbjct: 2158 QPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEA 2217

Query: 468  QPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLD 527
            + +     PE   V       E  P++     G +K  P     QVS+ + Q+E A    
Sbjct: 2218 EEEAQ---PEPEGVETPEAEGEAQPESEGETQGEKKGSP-----QVSLGDGQSEEASESS 2269

Query: 528  VGECENRAREMPGVWG 543
                E+R    P   G
Sbjct: 2270 SPVPEDRPTPPPSPGG 2285



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 70/331 (21%), Positives = 129/331 (38%), Gaps = 34/331 (10%)

Query: 208  KSDPPEGSE--EAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSS 265
            +SD  EG E  EA        E  + P    D  + +    PE E  EA E   +    S
Sbjct: 1828 QSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPES 1887

Query: 266  EEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQ 325
            E+    E   ++Q +++        K+ Q      EALE +                  +
Sbjct: 1888 EDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETE-----------------GE 1930

Query: 326  TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHS 385
             +P     + Q   +  ++A+ QT PE  V++ ++ + + Q E+E  + ++ +V+ Q  +
Sbjct: 1931 DEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQ-EA 1989

Query: 386  QGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
            +G  Q + +    P  + + ++Q       P    ++ Q + + +   +V  + Q +   
Sbjct: 1990 EGEAQPESEDVEAP--EAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKT--E 2045

Query: 446  QEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTL 505
             +  P    V+ PE   E    + +V     E  P    V       DA EA G   +  
Sbjct: 2046 GDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDV-------DAQEAEG---EAQ 2095

Query: 506  PEPVGTQVSMEEIQNESACGLDVGECENRAR 536
            PE  G +    E + + A G++  E E  A+
Sbjct: 2096 PESEGVEAPEAEGEAQKAEGIEAPETEGEAQ 2126



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 60/265 (22%), Positives = 111/265 (41%), Gaps = 28/265 (10%)

Query: 181  PQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQ-DLPPCPEDI- 238
            P+ +   +       + +     P  D  + PE  EEA E   +  E + +  P  ED+ 
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVD 2086

Query: 239  AKEKRTPA-PEPEPCEASELP-----AKRLRSSEEPTEKEPPGQ------LQVKAQPQAR 286
            A+E    A PE E  EA E       A+ + + E   E +P  +       + +AQP++ 
Sbjct: 2087 AQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESE 2146

Query: 287  MTVPKQTQTPDLLPEA--LEAQVLPR-FQPRVLQVQA-QVQSQTQPR-----IPSTDTQV 337
              V  Q    +  PE+  +EAQ      QP +  V+A + + + QP       P  + + 
Sbjct: 2147 -GVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEA 2205

Query: 338  QPKLQ----KQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQL 393
            QP+L+     +A+ +  PE   ++  + + + Q E+E + Q + +  PQ      +  + 
Sbjct: 2206 QPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEA 2265

Query: 394  QQEAEPLKQVQPQVQPQAHSQPPRQ 418
             + + P+ + +P   P      P Q
Sbjct: 2266 SESSSPVPEDRPTPPPSPGGDTPHQ 2290



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 63/306 (20%), Positives = 124/306 (40%), Gaps = 25/306 (8%)

Query: 181  PQKQARTSSSTTPNRKDSSSQTMPVED--KSDPPEGSEEAAEPRMDTPEDQ-DLPPCPED 237
            P+ +   +       +++  +  P  D  ++ P    EEA E   +T + + D  P  + 
Sbjct: 1995 PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDG 2054

Query: 238  I-AKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTP 296
            + A E    A E E  E  E   +    SE+   +E  G+    AQP++      + +  
Sbjct: 2055 VEAPEAEEEAQEAEG-EVQEAEGEAHPESEDVDAQEAEGE----AQPESEGVEAPEAEGE 2109

Query: 297  DLLPEALEA-QVLPRFQPRVLQVQA-QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHL 354
                E +EA +     QP    ++A + + + QP     + Q     + +AQ ++     
Sbjct: 2110 AQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQ---DAEGEAQPESEGIEA 2166

Query: 355  VLQQKQVQPQLQQ----EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ 410
               +++ QP+L+     EAE + Q + +      ++G  Q +L+    P  + + Q +P+
Sbjct: 2167 QEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPE 2226

Query: 411  AHSQPPRQVQLQLQKQVQTQ----TYPQVHT---QAQPSVQPQEHPPAQVSVQPPEQTHE 463
                P  + + Q + + +TQ      PQV     Q++ + +     P      PP    +
Sbjct: 2227 GVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGD 2286

Query: 464  QPHTQP 469
             PH +P
Sbjct: 2287 TPHQRP 2292



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 36/164 (21%), Positives = 67/164 (40%), Gaps = 12/164 (7%)

Query: 385  SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
            ++G    + + EA+P  +     + +  +Q   + + + Q + +    P+   +AQP  +
Sbjct: 1832 AEGIEAPEAEGEAQPESEGVEAPEAEGDAQ---EAEGEAQPESEDVEAPEAEGEAQPESE 1888

Query: 445  PQEHPPAQVSVQP-------PEQTHE-QPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVE 496
              E P A+  VQP       PE   E QP T+   +L    +          +   +A +
Sbjct: 1889 DVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQ 1948

Query: 497  AGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPG 540
               G  +   E + +Q + EE Q ES   ++  E E   +E  G
Sbjct: 1949 EAEGQTQPESEVIESQEAEEEAQPESE-DVEALEVEVETQEAEG 1991


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 102/394 (25%), Positives = 132/394 (33%), Gaps = 50/394 (12%)

Query: 130 PGLAAPSLT-PPQLATPNLQQFFPQATRQSLLGP----PPVGVPMNPSQFNLSGRNPQKQ 184
           P  A PS+T PP  A P+LQ   P     SL  P    PP  + ++  Q   S  +P  Q
Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 185 ARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRT 244
           A  S  T   R+  +S T P    S PP+       P +  P    LP  P         
Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPD------SPPLQAP--LSLPASPPLQTSLSPA 476

Query: 245 PAPEPEPCEASELPAKRLRSSEEPTEK-----EPPGQLQVKAQPQARMTVPKQTQTPDLL 299
            +P   P     L A    +S  P         PP + Q    P +  T P    TP L 
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL- 535

Query: 300 PEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT-----SPEHL 354
                 + LP   P  LQ  +     T P + +        LQ      T     +P  +
Sbjct: 536 ------ENLPSLAPPPLQTAS--APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSI 587

Query: 355 VLQQKQVQPQLQQ---EAEPQKQVQPQVQPQAHSQGPRQVQLQQ-EAEPLKQVQPQVQPQ 410
                Q  P L     +  P   + P   P    Q P  + L   +A P     P + P 
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPP--PQAPPXLALPPLQAPPSPPASPPLSPL 645

Query: 411 AHSQPPRQVQLQ---LQKQVQTQTYPQVHT----QAQPSVQPQEHPPAQVS---VQPPEQ 460
           A   P     L    LQ        P V       A P V P   PP+Q       PP Q
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 705

Query: 461 THEQPHTQPQVSLLA--PEQTPVVVHVCGLEMPP 492
               P   P +S  A  P Q P  +    L++PP
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 124/507 (24%), Positives = 162/507 (31%), Gaps = 80/507 (15%)

Query: 45  SPPQAPLPMAV-SRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRA---LLLQQLQGLDQF 100
           SPP  P   A  S   PP Q    L  +        L    LQ     L L  LQ     
Sbjct: 359 SPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418

Query: 101 AMPPATYDTAGLTM-PTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSL 159
             P      + LTM P  T  +L      SP  + P+ TPP   +P LQ         SL
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASL-----TSP--SRPASTPPD--SPPLQ------APLSL 463

Query: 160 LGPPPVGVPMNPSQFNLSGR---NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSE 216
              PP+   ++P+   LS     +P +   + +S +P    SS    P+E +S     S 
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523

Query: 217 EAAEPRMDTPEDQDLP---PCPEDIAKEKRT-------PAPEPEPCEA-----SELPAKR 261
           +     + TP  ++LP   P P   A    T       P P P P +A     +  P + 
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583

Query: 262 LRSSEEPTEKEPPGQLQVKAQ-----PQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
             S   P  + PP       Q     P + +  P     P L    L+A   P   P + 
Sbjct: 584 PSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643

Query: 317 QVQA---------QVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQ 367
            +            V     P  P     VQ      A    SP        Q  P L  
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS--ATPPSQAPPSL-- 699

Query: 368 EAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQ---------AHSQPPRQ 418
            A P  QV P   P +    P      Q   PL     QV P          + + PPR 
Sbjct: 700 -AAPPLQVPPS-PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757

Query: 419 VQLQLQKQVQTQTYPQVHTQAQPSVQPQEH-------PPAQVSVQPPEQTHEQPHTQPQV 471
             L     +Q    P       P  +P          PP Q    PP     Q    P  
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 817

Query: 472 SL------LAPEQTPVVVHVCGLEMPP 492
           SL        P Q P V+    L++PP
Sbjct: 818 SLPMSPLATPPPQAPPVLAAPLLQVPP 844



 Score = 57.4 bits (137), Expect = 6e-08
 Identities = 107/443 (24%), Positives = 143/443 (32%), Gaps = 42/443 (9%)

Query: 46  PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPA 105
           P   PL  ++S  + P      +  LQ  +S +  +      +L++  L+     A P  
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523

Query: 106 TYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPV 165
               A LT P   L NL          A+  LT P L TP      P     S L  PP 
Sbjct: 524 QTPPASLTTPP--LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP- 580

Query: 166 GVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDT 225
             P  PS    S   P  QA  + ++ P +   S    P+   + PP+     A P +  
Sbjct: 581 --PETPS----SIATPPPQAPPALASPPLQGLPSPPLSPL--ATPPPQAPPXLALPPLQA 632

Query: 226 PEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQA 285
           P        P   A    +P   P P   + L    L++   P    P   +Q    P A
Sbjct: 633 P--------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP---VQAPFSPPA 681

Query: 286 RMTVPKQTQTPDLLPEALEAQVL-----PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
              V      P   P +L A  L     P   P  +   A    Q  P + +   QV P 
Sbjct: 682 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQVPP- 739

Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQ---PQAHSQGPRQVQLQQEA 397
               A    SP        +V P L   A P  QV P      P +    P        A
Sbjct: 740 -SPPASPPMSPS--ATPPPRVPPLL---AAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 398 EPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQV-HTQAQPSVQPQEHPPAQVSVQ 456
            P  Q  P        Q P      L         PQ     A P +Q    PPA  ++Q
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853

Query: 457 PPEQTHEQPHTQPQVSLLAPEQT 479
            P +    P   P  S+  P  T
Sbjct: 854 APRR---PPTPGPDTSVSGPRLT 873



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 91/395 (23%), Positives = 133/395 (33%), Gaps = 48/395 (12%)

Query: 119 LGNLRGYGMASP---GLAAPSLTPPQLATPNLQQFFPQATRQSL---LGPPPVGVPMNPS 172
           LG L    +A+P   G  A  + PP  A   L    P +   +    L PP    P +  
Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQ 355

Query: 173 QFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLP 232
                   P  QA  S +T P +   S QT+P      P +       P +        P
Sbjct: 356 TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP------PIQVPHSLTSPSLQA------P 403

Query: 233 PCPEDIAKEKRTPAPEPEPCEASE-----LPAKRLRSSEEPTE--KEPPGQLQVKAQPQA 285
           P P  ++  + T +      +A+       P +   S   P+     PP    ++A    
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463

Query: 286 RMTVPKQTQ-TPDLLPEALEAQVLPRFQPRVL---QVQAQVQSQTQPRIPSTDTQVQPKL 341
             + P QT  +P + P +    + P      L     QA + S   P + +  +   P L
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523

Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLK 401
           Q    + T+P  L        P LQ  + P      +  P      P    LQ    PL 
Sbjct: 524 QTPPASLTTPP-LENLPSLAPPPLQTASAPLTTPHLETPP-----CPAPCPLQAPPSPLT 577

Query: 402 QVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVS---VQPP 458
              P+  P + + PP Q    L         P +     P + P   PP Q       PP
Sbjct: 578 TPPPET-PSSIATPPPQAPPALAS-------PPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 459 EQTHEQPHTQPQVSLLA--PEQTPVVVHVCGLEMP 491
            Q    P   P +S LA    Q P  + V  L+ P
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 664



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 77/342 (22%), Positives = 110/342 (32%), Gaps = 59/342 (17%)

Query: 162 PPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEP 221
           P PV  P   S     G   QK  R S+  T  R  ++          + P+ S  +A  
Sbjct: 111 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT----------EAPKRSALSAGA 160

Query: 222 RMDTPEDQDLPPCPEDIAKEKRT---------PAPEPEPCEASELPAKRLRSSEEPTEKE 272
           R DT       P P  +A+  R          PAP   P   +E P K + S+ E +  E
Sbjct: 161 RRDTSGPTPGTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219

Query: 273 PPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPS 332
           P         P AR               +L +   P   P     ++   ++  PR P+
Sbjct: 220 P--------SPAARRRPSAGGGLQRPASRSLSSSATPLSSP----ARSGPSARGTPRAPA 267

Query: 333 TDTQVQPK-LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQV 391
             +Q +PK LQ     Q +P                   P+K   P + P + S      
Sbjct: 268 HPSQPKPKGLQALRPPQVTP-------------------PRKDAAPALGPLSSSPLATPS 308

Query: 392 QLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPA 451
               +A P+        P   + PP                      A PS+Q    PPA
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPS------PPLATPLPLAPPSPSAPPSLQTLPSPPA 362

Query: 452 QVSVQ-PPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPP 492
               Q PP  T       P +  + P Q P  +    L+ PP
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404



 Score = 35.8 bits (81), Expect = 0.18
 Identities = 86/318 (27%), Positives = 106/318 (33%), Gaps = 75/318 (23%)

Query: 42   LQQSP-PQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQF 100
            LQ  P P A LPM+     PPQ P                       AL    LQ L   
Sbjct: 766  LQVPPSPPASLPMSPLAKPPPQAPP----------------------ALATPPLQALPS- 802

Query: 101  AMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQ-QFFPQA--TRQ 157
              PPA++       P+A+L         SP    P   PP LA P LQ    P A  T Q
Sbjct: 803  --PPASFPGQAPFSPSASL-------PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853

Query: 158  SLLGPPPVGVPMNPS----QFNLSGRNPQKQARTSSSTTPN---RKDSSSQTMPVEDKSD 210
            +   PP  G   + S       L+   P   +R+ SST         SSS T   E+   
Sbjct: 854  APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 913

Query: 211  PPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAP---------EPEPCEASELPAK- 260
               G E  A      P D +L  C    A   R PAP          P P   +  P   
Sbjct: 914  YDSGPEGGA--AASPPPDAELAACHP--AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 969

Query: 261  ----RLRSSEEPTEKEP-PGQLQVKAQP-------------QARMTVPKQTQTPDLLPEA 302
                 +  +E P    P PG L     P              A    PKQ +  +L   A
Sbjct: 970  DGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGA 1029

Query: 303  LEAQVLPRFQPRVLQVQA 320
            L+A V+     R L + A
Sbjct: 1030 LQASVVQHLLSRTLLLAA 1047


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 110/462 (23%), Positives = 162/462 (35%), Gaps = 104/462 (22%)

Query: 4    QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQ------------------------------ 33
            +QQQQQ QQQQQQ QQ QQQQ QQQQ QQQ                              
Sbjct: 2718 RQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTP 2777

Query: 34   -QLLQLQQLLQQSPPQAPLPMA------------VSRGLPPQQPQQPLLNLQGTNSASLL 80
              L+++Q+   Q PPQ P P A            V    PPQQ    L  +      +LL
Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALL 2837

Query: 81   NGSMLQRALLLQQLQGLDQFAMPPATYDTAGLT-MPTATLGNLRGYGMASPGLAAPSLTP 139
             G+ +                   A    A LT +PT+ L         +P  A  +L  
Sbjct: 2838 TGTTV-------------------ANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAK 2878

Query: 140  PQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKD-- 197
            P + +       P A   S   P    +PMN +  +++   PQK A  +    P      
Sbjct: 2879 PPVVS------VPAAVVSS---PGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQL 2929

Query: 198  -SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASE 256
                Q    + K+  P+ ++  A  +      Q   P  +        PA + +      
Sbjct: 2930 LKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTPI 2989

Query: 257  LPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVL 316
              A++L  +++        Q+QV   PQ    V +QT    +   A  +Q          
Sbjct: 2990 SQAQKLAGAQQVQT-----QIQVAKLPQ---VVQQQTPVASIQQVASASQ---------- 3031

Query: 317  QVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQ 376
            Q   Q  + TQ        Q+ P +   AQ        V+QQK +Q Q+   A    Q  
Sbjct: 3032 QASPQTVALTQATAAGQQVQMIPAVTATAQ--------VVQQKLIQQQVVTTASAPLQTP 3083

Query: 377  PQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQ 418
                P   +Q P       +   L+   P V+ +  ++PP Q
Sbjct: 3084 GAPNP---AQVPASSDSPSQQPKLQMRVPAVRLKTPTKPPCQ 3122



 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 119/525 (22%), Positives = 184/525 (35%), Gaps = 75/525 (14%)

Query: 16   QLQQLQQQQLQQQQ--LQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQG 73
            Q+  L+ +++ +++  L  QQ  Q   + Q  PPQ   P       PPQQP  PL   Q 
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQPAVAQPPPPQPQPPP------PPQQPPPPLPQPQA 2529

Query: 74   TNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLA 133
                    GS         Q Q   Q    P          P  T G   G      G  
Sbjct: 2530 A-------GSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTG---GSAAVLAGTI 2579

Query: 134  APSLTPPQLAT--------PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQA 185
              S+T   + T         N     P AT QS+     +  P+ P      G +   Q 
Sbjct: 2580 KTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI--NKRLASPVAPGALTTPGGSAPAQV 2637

Query: 186  RTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTP 245
               +   P    S +   P        +G               +L P    +    R+ 
Sbjct: 2638 -VHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTP----VQTPARSL 2692

Query: 246  APEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEA 305
             P+       +LP K +           P   Q+  Q Q +    +Q Q           
Sbjct: 2693 VPQVSQATGVQLPGKTI----------TPAHFQLLRQQQQQQQQQQQQQ----------- 2731

Query: 306  QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQL 365
            Q   + Q +  Q Q Q  + +Q ++P    Q Q   Q +A  + +PEHL+  QKQ     
Sbjct: 2732 QQQQQQQQQQQQQQQQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP 2791

Query: 366  QQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQK 425
             Q   PQ Q  P  QP A      QVQ+ Q ++P +Q  PQ+      +P   +      
Sbjct: 2792 PQPPPPQAQSAPP-QPTA------QVQV-QTSQPPQQQSPQLTTVTAPRPGALLTGTTVA 2843

Query: 426  QVQTQTYPQVHT---QAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVV 482
             +Q     +V T   QAQ  +Q Q   PAQV++  P        + P   + +P  T + 
Sbjct: 2844 NLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVV-----SVPAAVVSSPGVTTLP 2898

Query: 483  VHVCGLEMPPDAVEAGGGMEKTLPEPVGTQ----VSMEEIQNESA 523
            ++V G+ +     +   G +  + +PV  Q    +  + +Q + A
Sbjct: 2899 MNVAGISVAIGQPQKAAG-QTVVAQPVHMQQLLKLKQQAVQQQKA 2942



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 128/484 (26%), Positives = 175/484 (36%), Gaps = 89/484 (18%)

Query: 8    QQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQP 67
            Q L+QQQQQ QQ QQQQ QQQQ QQQQ  Q QQ    S                 Q Q P
Sbjct: 2715 QLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS-----------------QVQVP 2757

Query: 68   LLNLQGTNSASL-LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYG 126
             +  Q  + A +   G +    L+  Q Q L     PP     +    PTA         
Sbjct: 2758 QIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAPPQPTAQ-------- 2809

Query: 127  MASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQAR 186
                 +   +  PPQ  +P L          ++  P P  +    +  NL     Q    
Sbjct: 2810 -----VQVQTSQPPQQQSPQL---------TTVTAPRPGALLTGTTVANL-----QVARL 2850

Query: 187  TSSSTTPNRKDSSSQTMPVEDK----SDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
            T   T+  +     QT   +      + PP  S  AA   + +P    LP     I+   
Sbjct: 2851 TRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAV--VSSPGVTTLPMNVAGIS--- 2905

Query: 243  RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 302
                 +P+      + A+ +   +    K+   Q Q   QPQA        Q P  + + 
Sbjct: 2906 -VAIGQPQKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQA-------AQGPAAVQQK 2957

Query: 303  LEAQVL--PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
            + AQ +  P  Q +V    AQ   +TQ    +T      KL    Q QT  +   L    
Sbjct: 2958 ITAQQITTPGAQQKVAYA-AQPALKTQ--FLTTPISQAQKLAGAQQVQTQIQVAKL---- 3010

Query: 361  VQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQ--PQVQPQAHSQPPRQ 418
              PQ+ Q+  P   +Q QV   +    P+ V L Q     +QVQ  P V   A       
Sbjct: 3011 --PQVVQQQTPVASIQ-QVASASQQASPQTVALTQATAAGQQVQMIPAVTATA------- 3060

Query: 419  VQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQV--SVQPPEQTHEQPHTQPQVSLLAP 476
             Q+  QK +Q Q    V T + P   P    PAQV  S   P Q  +     P V L  P
Sbjct: 3061 -QVVQQKLIQQQV---VTTASAPLQTPGAPNPAQVPASSDSPSQQPKLQMRVPAVRLKTP 3116

Query: 477  EQTP 480
             + P
Sbjct: 3117 TKPP 3120



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 96/444 (21%), Positives = 143/444 (32%), Gaps = 110/444 (24%)

Query: 228  DQDLPPCP------EDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKA 281
            D+ LPP        E IAKEK+  A +              + +++P   +PP       
Sbjct: 2469 DKPLPPIQVASLRAERIAKEKKALADQ--------------QKAQQPAVAQPP------- 2507

Query: 282  QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP-- 339
             PQ +   P Q Q P  LP+   A   P   P  +Q Q Q Q QTQP+      + QP  
Sbjct: 2508 PPQPQPPPPPQ-QPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAI 2566

Query: 340  ---------------------------------------------KLQKQAQTQTSPEHL 354
                                                          + K+  +  +P  L
Sbjct: 2567 TTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSINKRLASPVAPGAL 2626

Query: 355  VLQQKQVQPQLQQEAEPQKQV------QPQVQPQAHSQGPRQV-----------QLQQEA 397
                     Q+     P + V       P +   A +QG R V            L    
Sbjct: 2627 TTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQ 2686

Query: 398  EPLKQVQPQVQ------------PQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQP 445
             P + + PQV               AH Q  RQ Q Q Q+Q Q Q   Q   Q Q   Q 
Sbjct: 2687 TPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 2746

Query: 446  QEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTL 505
            Q    +QV V   +   + P     V  L PE   + +    L+MPP         +   
Sbjct: 2747 QTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHL-IKMQKQKLQMPPQPPPPQA--QSAP 2803

Query: 506  PEPVG-TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSL-KVTILQSSDSRAFST 563
            P+P    QV   +   + +  L           + G   A   + ++T + +S  +A   
Sbjct: 2804 PQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLTGTTVANLQVARLTRVPTSQLQAQGQ 2863

Query: 564  VPLTPVPRPSDSVSSTPAATSTPS 587
            +  T  P+P+    + P   S P+
Sbjct: 2864 MQ-TQAPQPAQVALAKPPVVSVPA 2886



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 54/247 (21%), Positives = 93/247 (37%), Gaps = 42/247 (17%)

Query: 157 QSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQT-MPVEDKSDPPEGS 215
           Q L+     G+P  P    L+G+   +Q    S+  P +  +S  T +P      PP G 
Sbjct: 506 QQLMPTAQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGV 565

Query: 216 EEAA---------EPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSE 266
             AA         +P++   + Q   P      K ++   P P P  +S+LP    + ++
Sbjct: 566 PTAALSSALQFAQQPQVVEAQTQLQIP-----VKTQQPNVPIPAP-PSSQLPIPPSQPAQ 619

Query: 267 EPTEKEPPGQLQVKAQ-----PQ----ARMTVPKQTQTPDLLPEALEAQVLP-------- 309
                  PG++QV+A      PQ     R+ V      P  LP +  + + P        
Sbjct: 620 LALHVPTPGKVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGP 679

Query: 310 ---------RFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQ 360
                    R      +  + V S+T   + S  T+ Q   Q    +Q S +  + +Q  
Sbjct: 680 SPARSSPVNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQIT 739

Query: 361 VQPQLQQ 367
           ++ Q+ Q
Sbjct: 740 LENQVHQ 746



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 73/292 (25%), Positives = 103/292 (35%), Gaps = 55/292 (18%)

Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
           PQ  Q A  Q+Q Q Q  P   S GP          PL Q+  ++ P           LQ
Sbjct: 520 PQAAQLAG-QRQSQQQYDP---STGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQ 575

Query: 423 LQKQ---VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHE---QPHTQPQVSLLAP 476
             +Q   V+ QT  Q+  + Q    P   PP+     PP Q  +      T  +V + A 
Sbjct: 576 FAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQAS 635

Query: 477 EQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAR 536
           + + +   V    +P D            P P+ T  S   +   S  G           
Sbjct: 636 QLSSLPQMVASTRLPVDPA-------PPCPRPLPTS-STSSLAPVSGSG----------- 676

Query: 537 EMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCY 596
             PG   A  S  V    S+ ++A S V      R    V+S P    +P++ A      
Sbjct: 677 --PGPSPARSS-PVNRPSSATNKALSPV----TSRTPGVVASAPTKPQSPAQNA------ 723

Query: 597 ICKASCSSQQEFQDHMSEP-----QHQQRLGEIQH---MSQACLLSLLPVPR 640
                 SSQ   QD ++E      Q  QR+ E++     SQ  L  L   PR
Sbjct: 724 -----TSSQDSSQDTLTEQITLENQVHQRIAELRKAGLWSQRRLPKLQEAPR 770



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 48/183 (26%), Positives = 72/183 (39%), Gaps = 17/183 (9%)

Query: 17  LQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLP--PQQPQQPLLNLQGT 74
           LQ  QQ Q+ + Q Q Q  ++ QQ      P  P+P   S  LP  P QP Q  L++  T
Sbjct: 574 LQFAQQPQVVEAQTQLQIPVKTQQ------PNVPIPAPPSSQLPIPPSQPAQLALHVP-T 626

Query: 75  NSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGL-TMPTATLGNLRGYGMA-SPGL 132
                +  S L     L Q+    +  + PA      L T  T++L  + G G   SP  
Sbjct: 627 PGKVQVQASQLSS---LPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPAR 683

Query: 133 AAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTT 192
           ++P   P       L    P  +R   +       P +P+Q   S ++  +   T   T 
Sbjct: 684 SSPVNRPSSATNKALS---PVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITL 740

Query: 193 PNR 195
            N+
Sbjct: 741 ENQ 743



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 62/275 (22%), Positives = 89/275 (32%), Gaps = 62/275 (22%)

Query: 125  YGMASPG--LAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQ 182
            YG    G  +A PS  PP+ A P      PQ     L G PP+              NP+
Sbjct: 1432 YGQKPEGRTVAFPSTHPPRTAAPTTASAAPQG---PLRGRPPIAT---------FSANPE 1479

Query: 183  KQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEK 242
             +A    +  P +   +S + P   +  P   S  AA                       
Sbjct: 1480 AKA----AAAPFQTSQASASAP---RHQPASASSTAA----------------------- 1509

Query: 243  RTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEA 302
                    P   ++L A+    +  P +  P        QPQA      Q+  P  L   
Sbjct: 1510 -------SPAHPAKLRAQTTAQASTPGQPPP--------QPQAPSHAAGQSALPQRL--V 1552

Query: 303  LEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQ 362
            L +Q   R     +   AQ+ S T P+      +    LQ Q    T   H  L+Q    
Sbjct: 1553 LPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTL-SHSQLRQLTAG 1611

Query: 363  PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEA 397
              LQ +    + V    QP   + GP  +Q   +A
Sbjct: 1612 QPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQA 1646



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 52/232 (22%), Positives = 84/232 (36%), Gaps = 36/232 (15%)

Query: 237  DIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEK--EPPGQLQVKAQPQARM-----TV 289
            ++  +K+ P    E    S  PA R  +++    +  +P   +Q   +P+ R      T 
Sbjct: 1391 ELLSKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQP---VQYGQKPEGRTVAFPSTH 1447

Query: 290  PKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQT 349
            P +T  P     A +  +  R          + ++   P   S  +   P+ Q  + + T
Sbjct: 1448 PPRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASST 1507

Query: 350  --SPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQ------------ 395
              SP H        + + Q  A+     QP  QPQA S    Q  L Q            
Sbjct: 1508 AASPAH------PAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARL 1561

Query: 396  ---EAEPLKQVQPQVQPQAH-SQPPRQVQLQLQKQVQTQTYPQVH--TQAQP 441
               E   + Q+     PQ+  +QP   V LQ Q    T ++ Q+   T  QP
Sbjct: 1562 PSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQP 1613


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 70.5 bits (171), Expect = 7e-12
 Identities = 76/241 (31%), Positives = 106/241 (43%), Gaps = 24/241 (9%)

Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
           S + ++K+ P Q+ V     A MT   Q  TP  + + L+ QVL    P+ LQ   Q Q 
Sbjct: 75  SPKSSDKQRPLQVPVSV---AMMT--PQVITPQQMQQILQQQVL---SPQQLQALLQQQQ 126

Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
               +        Q +LQ+  + Q    HL L Q+Q Q Q QQ+ + Q+Q Q Q Q Q  
Sbjct: 127 AVMLQ--------QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQ 178

Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQ-VQTQTYPQVHTQAQPSV 443
            Q  +Q Q QQ+  P KQ + Q Q Q   Q     QL  Q+Q +Q Q   Q   Q   S+
Sbjct: 179 QQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ--QQHLLSL 236

Query: 444 QPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEK 503
           Q Q      +S+ PP Q      + PQ  L   E   +   V G+    D     GG++ 
Sbjct: 237 QRQ----GLISI-PPGQAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDL 291

Query: 504 T 504
           T
Sbjct: 292 T 292



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 152 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 206

Query: 65  QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
           QQ L   Q      LL    LQ+   LL  Q QGL      Q A+P  +   AGL+
Sbjct: 207 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 262



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 67/279 (24%), Positives = 115/279 (41%), Gaps = 36/279 (12%)

Query: 301 EALEA--QVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQ 358
           +AL+A  Q+L + Q   L+       Q   ++P +   + P++    Q Q   +  VL  
Sbjct: 56  QALQAARQLLLQQQTSGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQILQQQVLSP 115

Query: 359 KQVQPQLQQEAE---PQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQP 415
           +Q+Q  LQQ+      Q+Q+Q   + Q      + +Q QQ+ +  +Q Q Q Q Q   Q 
Sbjct: 116 QQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQ 175

Query: 416 PRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLA 475
            +Q Q Q Q+Q Q Q +P    + Q   Q Q+   A   +   +Q  +    Q Q  LL+
Sbjct: 176 QQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLS 235

Query: 476 PEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRA 535
            ++  ++       +PP         +  LP           +Q+    GL   E +   
Sbjct: 236 LQRQGLI------SIPPG--------QAALP-----------VQSLPQAGLSPAEIQQLW 270

Query: 536 REMPGVWG------AGGSLKVTILQSSDSRAFSTVPLTP 568
           +E+ GV          G L +T   SS + + +T   +P
Sbjct: 271 KEVTGVHSMEDNGIKHGGLDLTTNNSSSTTSSNTSKASP 309



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 123 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 182

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQ QQ      G  +         Q+ L  QQL    Q            L        +
Sbjct: 183 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 235

Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
           L+  G+ S  PG AA    SL    L+   +QQ + + T
Sbjct: 236 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 274



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 6/86 (6%)

Query: 12  QQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAV--SRGLPPQQPQQPLL 69
           QQQQ LQ  +Q  LQQQ      L   +   +Q P Q P+ +A+   + + PQQ QQ +L
Sbjct: 53  QQQQALQAARQLLLQQQT---SGLKSPKSSDKQRPLQVPVSVAMMTPQVITPQQMQQ-IL 108

Query: 70  NLQGTNSASLLNGSMLQRALLLQQLQ 95
             Q  +   L      Q+A++LQQ Q
Sbjct: 109 QQQVLSPQQLQALLQQQQAVMLQQQQ 134



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
           QQ QQ LQQQ    QQLQ        LQQQQ +     QLQ+  ++   Q  L +   + 
Sbjct: 102 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 155

Query: 59  LPPQQPQQ 66
              QQ QQ
Sbjct: 156 QQQQQQQQ 163


>gi|21327715 transcription elongation regulator 1 isoform 1 [Homo
           sapiens]
          Length = 1098

 Score = 70.1 bits (170), Expect = 9e-12
 Identities = 82/297 (27%), Positives = 107/297 (36%), Gaps = 51/297 (17%)

Query: 198 SSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASEL 257
           +  Q +     + PP        P M        PP P  +    R P P P P      
Sbjct: 22  AQQQALRFRGPAPPPNAVMRGPPPLMR-------PPPPFGMM---RGPPPPPRP------ 65

Query: 258 PAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLP---RFQPR 314
           P  R           PPG +     P      P   Q P  +P  + +   P    F P 
Sbjct: 66  PFGRPPFDPNMPPMPPPGGIP---PPMG----PPHLQRPPFMPPPMSSMPPPPGMMFPPG 118

Query: 315 VLQVQAQVQSQTQPRIPSTDT-QVQPKLQK------QAQTQ----TSPEHL-VLQQKQVQ 362
           +  V A       P +P T+   V+ K          A+T+    T P+ + V+QQ ++ 
Sbjct: 119 MPPVTAP----GTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDGVKVIQQSELT 174

Query: 363 PQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQ 422
           P L  +A+ Q Q Q Q Q QA +Q   Q Q Q +A    Q Q Q Q QA +Q   Q Q Q
Sbjct: 175 PMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQA----QAQAQAQAQAQAQAQAQAQAQ 230

Query: 423 LQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQT 479
            Q Q Q Q   QV  Q Q  VQ Q      V    P  +   P      S   P  T
Sbjct: 231 AQAQAQAQAQAQVQAQVQAQVQAQ-----AVGASTPTTSSPAPAVSTSTSSSTPSST 282



 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 124/528 (23%), Positives = 182/528 (34%), Gaps = 113/528 (21%)

Query: 161 GPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
           GPPP+  P  P  F +  R P    R      P   D +   MP      PP G      
Sbjct: 42  GPPPLMRP--PPPFGMM-RGPPPPPRPPFGRPPF--DPNMPPMPPPGGIPPPMGPPHLQR 96

Query: 221 PRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQV- 279
           P    P    +PP P  +        P   P  A   PA           K P G++   
Sbjct: 97  PPFMPPPMSSMPPPPGMMFP------PGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYY 150

Query: 280 -KAQPQARMTVP---KQTQTPDLLPE-ALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTD 334
                ++  T P   K  Q  +L P  A +AQV  + Q +  Q QAQ Q+Q Q +     
Sbjct: 151 NARTRESAWTKPDGVKVIQQSELTPMLAAQAQVQAQAQAQA-QAQAQAQAQAQAQ---AQ 206

Query: 335 TQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQA----------- 383
            Q Q + Q QAQ Q   +     Q Q Q Q Q +A+ Q QVQ QVQ QA           
Sbjct: 207 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSP 266

Query: 384 --------HSQGPRQVQ---------LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQ 426
                    S  P              Q  + P  Q Q      + + P   V       
Sbjct: 267 APAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTA 326

Query: 427 VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVC 486
              QT PQ H        PQ  PPA             PH+ PQ +   P   PV+V   
Sbjct: 327 TPVQTVPQPH--------PQTLPPA------------VPHSVPQPTTAIPAFPPVMV--- 363

Query: 487 GLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGG 546
               PP  V   G     +P P+     M+ +    +C         +   +PG+     
Sbjct: 364 ----PPFRVPLPG-----MPIPLPGVAMMQIV----SCPYVKTVATTKTGVLPGM----- 405

Query: 547 SLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPA--ATSTPSKQALQFFCYICKASCSS 604
                             P+ P+  P  +++++PA  A +T   +  ++     K    +
Sbjct: 406 ----------------APPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYN 449

Query: 605 QQEFQDHMSEPQHQQRLGEIQHMSQACLL--SLLPVPRDVLETEDEEP 650
            +  +    +PQ  +   +++   +  +   S  P+P   +ETE+E+P
Sbjct: 450 NRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLP---METEEEDP 494



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 79/391 (20%), Positives = 121/391 (30%), Gaps = 50/391 (12%)

Query: 26  QQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP-QQPQQPLLNLQGTNSASLLNGSM 84
           + ++    +L   QQ   +    AP P AV RG PP  +P  P   ++G           
Sbjct: 10  ESERFNPGELRMAQQQALRFRGPAPPPNAVMRGPPPLMRPPPPFGMMRGPPPPPR----- 64

Query: 85  LQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLAT 144
                          F  PP  +D     MP          G   P +  P L  P    
Sbjct: 65  -------------PPFGRPP--FDPNMPPMPPP--------GGIPPPMGPPHLQRPPFMP 101

Query: 145 PNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMP 204
           P +    P        G PPV  P  P+        P  +     + TP+ K        
Sbjct: 102 PPMSSMPPPPGMMFPPGMPPVTAPGTPAL-------PPTEEIWVENKTPDGKVYYYNART 154

Query: 205 VEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
            E     P+G +   +  + TP              + +  A      +A +  A+    
Sbjct: 155 RESAWTKPDGVKVIQQSEL-TPMLAAQAQVQAQAQAQAQAQAQAQAQAQA-QAQAQAQAQ 212

Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
           ++   + +   Q Q +AQ QA+     Q Q    +   ++AQ +    P        V +
Sbjct: 213 AQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVST 272

Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
            T    PS+ T         AQT ++P      Q Q        A P   V         
Sbjct: 273 STSSSTPSSTTSTTTTATSVAQTVSTP----TTQDQTPSSAVSVATPTVSVS-------- 320

Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQP 415
           +  P    +Q   +P  Q  P   P +  QP
Sbjct: 321 TPAPTATPVQTVPQPHPQTLPPAVPHSVPQP 351



 Score = 33.5 bits (75), Expect = 0.91
 Identities = 75/319 (23%), Positives = 109/319 (34%), Gaps = 39/319 (12%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQ-QLLQQSPPQAPLPM-AVSRGLPPQ 62
           Q Q Q Q Q Q   Q Q Q   Q Q+Q Q   Q+Q Q +  S P    P  AVS      
Sbjct: 218 QAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQVQAQAVGASTPTTSSPAPAVSTSTSSS 277

Query: 63  QPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMP------PATYDTAGLTMP- 115
            P         T +A+ +  ++       Q        A P      PA   T   T+P 
Sbjct: 278 TPSS---TTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQ 334

Query: 116 --TATLGNLRGYGMASPGLAAPS----LTPP-QLATPNLQQFFPQATRQSLLGPPPVGVP 168
               TL     + +  P  A P+    + PP ++  P +    P      ++  P V   
Sbjct: 335 PHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTV 394

Query: 169 MNPSQFNLSGR--------NPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAE 220
                  L G         +PQ     S +T       S  T            +    E
Sbjct: 395 ATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLE 454

Query: 221 PRMDTPED-QDLPPCPEDIAKEKRTPAPEPEPCEA-----SELPAKRLR---SSEEPTEK 271
              + P++ ++     E I +  + P+ EP P E       E P K ++     EE TE+
Sbjct: 455 STWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEE 514

Query: 272 EPPGQLQVKAQPQARMTVP 290
           E   Q   KA+P A   +P
Sbjct: 515 EKAAQ---KAKPVATAPIP 530


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 70/225 (31%), Positives = 97/225 (43%), Gaps = 19/225 (8%)

Query: 281 AQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPK 340
           A P +   +  Q  TP  + + L+ QVL    P+ LQ   Q Q     +        Q +
Sbjct: 111 AVPVSVAMMTPQVITPQQMQQILQQQVL---SPQQLQALLQQQQAVMLQ--------QQQ 159

Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
           LQ+  + Q    HL L Q+Q Q Q QQ+ + Q+Q Q Q Q Q   Q  +Q Q QQ+  P 
Sbjct: 160 LQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPG 219

Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQ-VQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPE 459
           KQ + Q Q Q   Q     QL  Q+Q +Q Q   Q   Q   S+Q Q      +S+ PP 
Sbjct: 220 KQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQ--QQHLLSLQRQ----GLISI-PPG 272

Query: 460 QTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKT 504
           Q      + PQ  L   E   +   V G+    D     GG++ T
Sbjct: 273 QAALPVQSLPQAGLSPAEIQQLWKEVTGVHSMEDNGIKHGGLDLT 317



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 12/116 (10%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           QQQQQ QQQQQQ QQ QQQQ QQQQ QQQQ  Q QQ  QQ P +             QQ 
Sbjct: 177 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGK-----QAKEQQQQQQQ 231

Query: 65  QQPLLNLQGTNSASLLNGSMLQRA--LLLQQLQGL-----DQFAMPPATYDTAGLT 113
           QQ L   Q      LL    LQ+   LL  Q QGL      Q A+P  +   AGL+
Sbjct: 232 QQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQRQGLISIPPGQAALPVQSLPQAGLS 287



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 51/159 (32%), Positives = 64/159 (40%), Gaps = 15/159 (9%)

Query: 5   QQQQQLQQQQQQLQQL---QQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPP 61
           QQQQ +  QQQQLQ+    QQ+QL  Q LQQQQ  Q QQ  QQ   Q        +    
Sbjct: 148 QQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 207

Query: 62  QQPQQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGN 121
           QQ QQ      G  +         Q+ L  QQL    Q            L        +
Sbjct: 208 QQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLL-------S 260

Query: 122 LRGYGMAS--PGLAA---PSLTPPQLATPNLQQFFPQAT 155
           L+  G+ S  PG AA    SL    L+   +QQ + + T
Sbjct: 261 LQRQGLISIPPGQAALPVQSLPQAGLSPAEIQQLWKEVT 299



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 49/168 (29%), Positives = 66/168 (39%), Gaps = 27/168 (16%)

Query: 274 PGQLQVKAQPQARMTVPKQT-------QTPDLLPEALEAQVLPRFQPRVLQVQAQV-QSQ 325
           P QLQ   Q Q  + + +Q        Q   L  + L+ Q   + Q +  Q Q Q  Q Q
Sbjct: 140 PQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQ 199

Query: 326 TQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHS 385
            Q        Q Q + Q+Q Q Q  P     +Q+Q Q Q QQ A  Q   Q Q+      
Sbjct: 200 QQ-------QQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQL------ 246

Query: 386 QGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYP 433
               Q+Q  Q+ + L  +Q Q      S PP Q  L +Q   Q    P
Sbjct: 247 ---LQMQQLQQQQHLLSLQRQ---GLISIPPGQAALPVQSLPQAGLSP 288



 Score = 34.7 bits (78), Expect = 0.41
 Identities = 39/148 (26%), Positives = 64/148 (43%), Gaps = 15/148 (10%)

Query: 280 KAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQP 339
           K Q Q  + + +Q Q      +  + Q   + Q +  Q Q Q Q Q Q +        + 
Sbjct: 166 KQQEQLHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQ 225

Query: 340 KLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEP 399
           + Q+Q Q Q + + LV QQ+ +Q Q  Q+ +    +Q         QG   +   Q A P
Sbjct: 226 QQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHLLSLQ--------RQGLISIPPGQAALP 277

Query: 400 LKQVQPQVQPQAHSQPPRQVQLQLQKQV 427
           ++ +     PQA    P ++Q QL K+V
Sbjct: 278 VQSL-----PQA-GLSPAEIQ-QLWKEV 298



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 26/68 (38%), Positives = 32/68 (47%), Gaps = 11/68 (16%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLL-----QLQQLLQQSPPQAPLPMAVSRG 58
           QQ QQ LQQQ    QQLQ        LQQQQ +     QLQ+  ++   Q  L +   + 
Sbjct: 127 QQMQQILQQQVLSPQQLQAL------LQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQ 180

Query: 59  LPPQQPQQ 66
              QQ QQ
Sbjct: 181 QQQQQQQQ 188


>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
           sapiens]
          Length = 691

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 66/238 (27%), Positives = 93/238 (39%), Gaps = 45/238 (18%)

Query: 341 LQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPL 400
           LQ  +   +  + L LQ +Q Q Q QQ+  P     PQ  PQA SQ  +Q        PL
Sbjct: 169 LQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQ--------PL 220

Query: 401 KQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQ 460
           +   PQ  P A  QPP     QLQ+  Q Q + Q H+ +Q   QP    P Q S  PP  
Sbjct: 221 QPTPPQQPPPASQQPPAPTS-QLQQAPQPQQH-QPHSHSQNQNQPS---PTQQSSSPP-- 273

Query: 461 THEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQN 520
             ++P   P   L +P   P  + +    +   A  A                +M  I +
Sbjct: 274 --QKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAA--------------AAMSSIAS 317

Query: 521 ESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSS 578
             A G       N    + GV G        ++ ++  +   T+PL P P PS   +S
Sbjct: 318 SQAFG-------NALSSLQGVTG-------QLVTNAQGQIIGTIPLMPNPGPSSQAAS 361



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 46/136 (33%), Positives = 54/136 (39%), Gaps = 11/136 (8%)

Query: 5   QQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQP 64
           Q  Q       QLQQLQ Q  QQQQ QQQQ         Q  PQAP   +  + L P  P
Sbjct: 167 QNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQHPQPAPQAP-SQSQQQPLQPTPP 225

Query: 65  QQPLLNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRG 124
           QQP    Q   + +    S LQ+A   QQ Q             T   + P        G
Sbjct: 226 QQPPPASQQPPAPT----SQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPG 281

Query: 125 YGMASPGLAAPSLTPP 140
           +G+ SP      LTPP
Sbjct: 282 HGLPSP------LTPP 291



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 64/289 (22%), Positives = 100/289 (34%), Gaps = 40/289 (13%)

Query: 112 LTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNP 171
           LT+PTA L N++  G+ +   A   +T P                Q+L     +   +  
Sbjct: 139 LTLPTANLTNIQ--GLVAAAAAGGIMTLP---------------LQNLQATSSLNSQLQQ 181

Query: 172 SQFNLSGRNPQKQARTSSSTTPN-----RKDSSSQTMPVE--DKSDPPEGSEEAAEPRMD 224
            Q  L  +  Q+Q +   ST  +     +  S SQ  P++      PP  S++   P   
Sbjct: 182 LQLQLQQQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAP--- 238

Query: 225 TPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEE---PTEKEPPGQLQVKA 281
           T + Q  P   +           +P P + S  P ++   S     P+   PP  LQ+  
Sbjct: 239 TSQLQQAPQPQQHQPHSHSQNQNQPSPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVN 298

Query: 282 QPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKL 341
            P A            +         L   Q    Q+    Q Q    IP       P  
Sbjct: 299 NPLASQAAAAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIP---LMPNPGP 355

Query: 342 QKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQ---KQVQPQVQPQAHSQG 387
             QA + T      LQ + + PQL   A+ Q     +  Q+ P  ++QG
Sbjct: 356 SSQAASGTQG----LQVQPITPQLLTNAQGQIIATVIGNQILPVINTQG 400



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 75/318 (23%), Positives = 111/318 (34%), Gaps = 45/318 (14%)

Query: 69  LNLQGTNSASLLNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMA 128
           L LQ   + S LN  + Q  L LQQ Q   Q   PP+T                      
Sbjct: 164 LPLQNLQATSSLNSQLQQLQLQLQQQQQQQQQQPPPSTNQ------------------HP 205

Query: 129 SPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTS 188
            P   APS +  Q   P   Q  P A++Q    PP    P +  Q     + PQ Q    
Sbjct: 206 QPAPQAPSQSQQQPLQPTPPQQPPPASQQ----PP---APTSQLQ-----QAPQPQQHQP 253

Query: 189 SSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPE 248
            S + N+    +Q  P +  S PP+   ++    + +P     PP P  +          
Sbjct: 254 HSHSQNQ----NQPSPTQQSSSPPQKPSQSPGHGLPSPL---TPPNPLQLVNNPLASQAA 306

Query: 249 PEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVL 308
                 S + + +   +   + +   GQL   AQ Q   T+P     P+  P +  A   
Sbjct: 307 AAAAAMSSIASSQAFGNALSSLQGVTGQLVTNAQGQIIGTIPLM---PNPGPSSQAASGT 363

Query: 309 PRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQE 368
              Q + +  Q    +Q Q        Q+ P +  Q  T  SP    ++  Q   Q  Q 
Sbjct: 364 QGLQVQPITPQLLTNAQGQIIATVIGNQILPVINTQGIT-LSP----IKPGQQLHQPSQT 418

Query: 369 AEPQKQVQPQVQPQAHSQ 386
           +  Q   Q  +   AHSQ
Sbjct: 419 SVGQAASQGNLLHLAHSQ 436



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 30/78 (38%), Positives = 33/78 (42%), Gaps = 4/78 (5%)

Query: 4   QQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPP---QAPLPMAVSRGLP 60
           QQQQQQ QQ      Q  Q   Q     QQQ LQ     QQ PP   Q P P +  +  P
Sbjct: 188 QQQQQQQQQPPPSTNQHPQPAPQAPSQSQQQPLQ-PTPPQQPPPASQQPPAPTSQLQQAP 246

Query: 61  PQQPQQPLLNLQGTNSAS 78
             Q  QP  + Q  N  S
Sbjct: 247 QPQQHQPHSHSQNQNQPS 264


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)

Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
           N +++ + +S T    + SS  ++T  +   + P EG  E+++ R    E       P+D
Sbjct: 93  NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 149

Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
           I ++ R+     P+P+    ++     +++  ++ P  + P G   V   P +      Q
Sbjct: 150 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 206

Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
             TP   P A    V P+  P   Q   Q Q+ T P +P T  Q  P L  Q      P 
Sbjct: 207 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 263

Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
                   +QP      +P        QP  H QGP      Q    L+   P   PQ  
Sbjct: 264 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 318

Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
             PP+  Q Q          YP    Q   +Q ++Q Q+ P  Q +   P    H + P 
Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378

Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
           T P   L AP+      H+ G
Sbjct: 379 TTPIPQLPAPQAHKHPPHLSG 399



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)

Query: 176 LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
           L  + P  QA T  +  P+     +  +P    +      PP+GS  A++     P    
Sbjct: 180 LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 235

Query: 231 LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
            P  P              +R P+P P P  +   P + L  S      P+  +PP   Q
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 295

Query: 279 VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
               P +    P         P  L         P+  Q QA + +      P T  Q+ 
Sbjct: 296 GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 346

Query: 339 PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
           P  Q   Q+Q  P    L    +  P ++    P   +     PQAH       GP    
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 404

Query: 393 LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
           +     P   ++P      H  PP      LQ   Q+Q  P    Q     Q Q  PP  
Sbjct: 405 MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 463

Query: 453 VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
            S  PP   H+     P  Q   +     P+    C    P  +    G      P   G
Sbjct: 464 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 518

Query: 511 TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
              S   I   S+C L   + +  A                 L  ++       P +P P
Sbjct: 519 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 554

Query: 571 RPSDSVSSTPAATSTPS--KQALQFFCYI 597
            P  S S  P    TPS   Q+ +F+ ++
Sbjct: 555 PPPRSPSPEPTVVDTPSHASQSARFYKHL 583



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)

Query: 46  PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
           PP  PL  +  +   P   Q PL         SL  G +LQ         L  Q  QG  
Sbjct: 270 PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 329

Query: 99  QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
                P A Y    L +P +              L    +A P +  P  TP PQL  P 
Sbjct: 330 PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 389

Query: 147 LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
             +  P  +  S       L PPP   P+           +P    L    PQ Q   SS
Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 446

Query: 190 STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
              P    + SQ +P    S PP G  + A                       P   TP 
Sbjct: 447 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 505

Query: 228 ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
                   PPC    A           P    ++  + L  +EEP    PP        P
Sbjct: 506 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 557

Query: 284 QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
           ++    P    TP     A ++    +   R     A+      P   S       KL K
Sbjct: 558 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 607

Query: 344 QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
           + +          +QK  +   ++E E +K+ + + + +   +  R  +    A   +  
Sbjct: 608 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 664

Query: 404 QPQVQPQAHSQP 415
            PQ+    H +P
Sbjct: 665 DPQLSGPGHMRP 676


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)

Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
           N +++ + +S T    + SS  ++T  +   + P EG  E+++ R    E       P+D
Sbjct: 647 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 703

Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
           I ++ R+     P+P+    ++     +++  ++ P  + P G   V   P +      Q
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 760

Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
             TP   P A    V P+  P   Q   Q Q+ T P +P T  Q  P L  Q      P 
Sbjct: 761 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 817

Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
                   +QP      +P        QP  H QGP      Q    L+   P   PQ  
Sbjct: 818 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 872

Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
             PP+  Q Q          YP    Q   +Q ++Q Q+ P  Q +   P    H + P 
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
           T P   L AP+      H+ G
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSG 953



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)

Query: 176  LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
            L  + P  QA T  +  P+     +  +P    +      PP+GS  A++     P    
Sbjct: 734  LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 789

Query: 231  LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
             P  P              +R P+P P P  +   P + L  S      P+  +PP   Q
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 849

Query: 279  VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
                P +    P         P  L         P+  Q QA + +      P T  Q+ 
Sbjct: 850  GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 900

Query: 339  PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
            P  Q   Q+Q  P    L    +  P ++    P   +     PQAH       GP    
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 393  LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
            +     P   ++P      H  PP      LQ   Q+Q  P    Q     Q Q  PP  
Sbjct: 959  MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 453  VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
             S  PP   H+     P  Q   +     P+    C    P  +    G      P   G
Sbjct: 1018 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 1072

Query: 511  TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
               S   I   S+C L   + +  A                 L  ++       P +P P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 1108

Query: 571  RPSDSVSSTPAATSTPS--KQALQFFCYI 597
             P  S S  P    TPS   Q+ +F+ ++
Sbjct: 1109 PPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 94/452 (20%), Positives = 154/452 (34%), Gaps = 74/452 (16%)

Query: 163 PPVGVPMNPSQF----------NLSGRNPQKQARTSSSTTPNRKDSSSQ-------TMPV 205
           PP+  P++P  F           LSG++  +  R+  S +  R     Q       T P+
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPI 602

Query: 206 -EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
            ED       S  AA    +  + + +    + + +E  +P    +         +R + 
Sbjct: 603 NEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK--------RQREKV 654

Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
           + +  E +     + K Q  +R   P + +       ++  +      P+ +    Q   
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID---QDNR 709

Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
            T P IPS           ++ + +S +  +LQ +    Q      P     P   PQ  
Sbjct: 710 STSPSIPSPQ-------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
           + GP              V PQ  P A SQ P       Q Q  T   P  H Q  P++ 
Sbjct: 763 TPGP--------TPSATAVPPQGSPTA-SQAPN------QPQAPTAPVPHTHIQQAPALH 807

Query: 445 PQE----HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 500
           PQ     HPP   S  PP Q       QP     AP      +H  G    P +++AG  
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPS----APSHAQPPLHGQG-PPGPHSLQAGPL 862

Query: 501 MEKT-LPEPVGTQVSMEEIQNESACGLD-VGECENRAREMPGVWGAGGSLKVTILQSSDS 558
           ++    P+P G  +  +  Q ++  G        + + ++P    A        LQS   
Sbjct: 863 LQHPGPPQPFG--LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA--------LQSQQP 912

Query: 559 RAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA 590
                +P  P+  P      T      P+ QA
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)

Query: 46   PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
            PP  PL  +  +   P   Q PL         SL  G +LQ         L  Q  QG  
Sbjct: 824  PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883

Query: 99   QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
                 P A Y    L +P +              L    +A P +  P  TP PQL  P 
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943

Query: 147  LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
              +  P  +  S       L PPP   P+           +P    L    PQ Q   SS
Sbjct: 944  AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 1000

Query: 190  STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
               P    + SQ +P    S PP G  + A                       P   TP 
Sbjct: 1001 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059

Query: 228  ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
                    PPC    A           P    ++  + L  +EEP    PP        P
Sbjct: 1060 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 1111

Query: 284  QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
            ++    P    TP     A ++    +   R     A+      P   S       KL K
Sbjct: 1112 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 1161

Query: 344  QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
            + +          +QK  +   ++E E +K+ + + + +   +  R  +    A   +  
Sbjct: 1162 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 1218

Query: 404  QPQVQPQAHSQP 415
             PQ+    H +P
Sbjct: 1219 DPQLSGPGHMRP 1230


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 67.8 bits (164), Expect = 4e-11
 Identities = 79/321 (24%), Positives = 122/321 (38%), Gaps = 27/321 (8%)

Query: 180 NPQKQARTSSSTTPNRKDSS--SQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPED 237
           N +++ + +S T    + SS  ++T  +   + P EG  E+++ R    E       P+D
Sbjct: 647 NKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSS---DPKD 703

Query: 238 IAKEKRT-----PAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQ 292
           I ++ R+     P+P+    ++     +++  ++ P  + P G   V   P +      Q
Sbjct: 704 IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTG---VTPAPSSAPPGTPQ 760

Query: 293 TQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPE 352
             TP   P A    V P+  P   Q   Q Q+ T P +P T  Q  P L  Q      P 
Sbjct: 761 LPTPGPTPSA--TAVPPQGSPTASQAPNQPQAPTAP-VPHTHIQQAPALHPQRPPSPHPP 817

Query: 353 HLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAH 412
                   +QP      +P        QP  H QGP      Q    L+   P   PQ  
Sbjct: 818 PHPSPHPPLQPLTGSAGQP--SAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP---PQPF 872

Query: 413 SQPPRQVQLQLQKQVQ-TQTYPQVHTQ---AQPSVQPQEHPPAQ-VSVQPPEQTH-EQPH 466
             PP+  Q Q          YP    Q   +Q ++Q Q+ P  Q +   P    H + P 
Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932

Query: 467 TQPQVSLLAPEQTPVVVHVCG 487
           T P   L AP+      H+ G
Sbjct: 933 TTPIPQLPAPQAHKHPPHLSG 953



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 98/449 (21%), Positives = 142/449 (31%), Gaps = 72/449 (16%)

Query: 176  LSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSD-----PPEGSEEAAEPRMDTPEDQD 230
            L  + P  QA T  +  P+     +  +P    +      PP+GS  A++     P    
Sbjct: 734  LQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQ----APNQPQ 789

Query: 231  LPPCP--------EDIAKEKRTPAPEPEPCEASELPAKRLRSS----EEPTEKEPPGQLQ 278
             P  P              +R P+P P P  +   P + L  S      P+  +PP   Q
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQ 849

Query: 279  VKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQ 338
                P +    P         P  L         P+  Q QA + +      P T  Q+ 
Sbjct: 850  GPPGPHSLQAGPLLQHPGPPQPFGLP--------PQASQGQAPLGTSPAAAYPHTSLQL- 900

Query: 339  PKLQKQAQTQTSPEHLVLQQKQV-QPQLQQEAEPQKQVQPQVQPQAHSQ-----GPRQVQ 392
            P  Q   Q+Q  P    L    +  P ++    P   +     PQAH       GP    
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP--PTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 393  LQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQ 452
            +     P   ++P      H  PP      LQ   Q+Q  P    Q     Q Q  PP  
Sbjct: 959  MNANLPPPPALKPLSSLSTH-HPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP 1017

Query: 453  VSVQPPEQTHEQPHTQP--QVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVG 510
             S  PP   H+     P  Q   +     P+    C    P  +    G      P   G
Sbjct: 1018 AS-HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC----PSTSTPPAGPGTSAQPPCSG 1072

Query: 511  TQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVP 570
               S   I   S+C L   + +  A                 L  ++       P +P P
Sbjct: 1073 AAASGGSIAGGSSCPLPTVQIKEEA-----------------LDDAEE------PESP-P 1108

Query: 571  RPSDSVSSTPAATSTPS--KQALQFFCYI 597
             P  S S  P    TPS   Q+ +F+ ++
Sbjct: 1109 PPPRSPSPEPTVVDTPSHASQSARFYKHL 1137



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 94/452 (20%), Positives = 154/452 (34%), Gaps = 74/452 (16%)

Query: 163 PPVGVPMNPSQF----------NLSGRNPQKQARTSSSTTPNRKDSSSQ-------TMPV 205
           PP+  P++P  F           LSG++  +  R+  S +  R     Q       T P+
Sbjct: 543 PPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPI 602

Query: 206 -EDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRS 264
            ED       S  AA    +  + + +    + + +E  +P    +         +R + 
Sbjct: 603 NEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNK--------RQREKV 654

Query: 265 SEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQS 324
           + +  E +     + K Q  +R   P + +       ++  +      P+ +    Q   
Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE--GSSDPKDID---QDNR 709

Query: 325 QTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAH 384
            T P IPS           ++ + +S +  +LQ +    Q      P     P   PQ  
Sbjct: 710 STSPSIPSPQ-------DNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLP 762

Query: 385 SQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQ 444
           + GP              V PQ  P A SQ P       Q Q  T   P  H Q  P++ 
Sbjct: 763 TPGP--------TPSATAVPPQGSPTA-SQAPN------QPQAPTAPVPHTHIQQAPALH 807

Query: 445 PQE----HPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGG 500
           PQ     HPP   S  PP Q       QP     AP      +H  G    P +++AG  
Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPS----APSHAQPPLHGQG-PPGPHSLQAGPL 862

Query: 501 MEKT-LPEPVGTQVSMEEIQNESACGLD-VGECENRAREMPGVWGAGGSLKVTILQSSDS 558
           ++    P+P G  +  +  Q ++  G        + + ++P    A        LQS   
Sbjct: 863 LQHPGPPQPFG--LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSA--------LQSQQP 912

Query: 559 RAFSTVPLTPVPRPSDSVSSTPAATSTPSKQA 590
                +P  P+  P      T      P+ QA
Sbjct: 913 PREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 92/432 (21%), Positives = 133/432 (30%), Gaps = 87/432 (20%)

Query: 46   PPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASLLNGSMLQR-------ALLLQQLQGLD 98
            PP  PL  +  +   P   Q PL         SL  G +LQ         L  Q  QG  
Sbjct: 824  PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQA 883

Query: 99   QF-AMPPATYDTAGLTMPTATLG----------NLRGYGMASPGLAAPSLTP-PQLATPN 146
                 P A Y    L +P +              L    +A P +  P  TP PQL  P 
Sbjct: 884  PLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 943

Query: 147  LQQFFPQATRQS------LLGPPPVGVPM-----------NPSQFNLSGRNPQKQARTSS 189
              +  P  +  S       L PPP   P+           +P    L    PQ Q   SS
Sbjct: 944  AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM---PQSQPLPSS 1000

Query: 190  STTPNRKDSSSQTMPVEDKSDPPEGSEEAAE----------------------PRMDTPE 227
               P    + SQ +P    S PP G  + A                       P   TP 
Sbjct: 1001 PAQPPGL-TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP 1059

Query: 228  ----DQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQP 283
                    PPC    A           P    ++  + L  +EEP    PP        P
Sbjct: 1060 AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPP--------P 1111

Query: 284  QARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQK 343
            ++    P    TP     A ++    +   R     A+      P   S       KL K
Sbjct: 1112 RSPSPEPTVVDTPS---HASQSARFYKHLDRGYNSCARTDLYFMPLAGS-------KLAK 1161

Query: 344  QAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQV 403
            + +          +QK  +   ++E E +K+ + + + +   +  R  +    A   +  
Sbjct: 1162 KREEAIEKAKREAEQKARE---EREREKEKEKEREREREREREAERAAKASSSAHEGRLS 1218

Query: 404  QPQVQPQAHSQP 415
             PQ+    H +P
Sbjct: 1219 DPQLSGPGHMRP 1230


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,137,994
Number of Sequences: 37866
Number of extensions: 2580995
Number of successful extensions: 49974
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 508
Number of HSP's successfully gapped in prelim test: 1100
Number of HSP's that attempted gapping in prelim test: 20551
Number of HSP's gapped (non-prelim): 14630
length of query: 898
length of database: 18,247,518
effective HSP length: 111
effective length of query: 787
effective length of database: 14,044,392
effective search space: 11052936504
effective search space used: 11052936504
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press