Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 42544159
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42544159 heat shock 105kD [Homo sapiens]
(858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42544159 heat shock 105kD [Homo sapiens] 1718 0.0
gi|38327039 heat shock 70kDa protein 4 [Homo sapiens] 1082 0.0
gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens] 992 0.0
gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85
gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens] 314 2e-85
gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens] 274 2e-73
gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens] 271 1e-72
gi|167466173 heat shock 70kDa protein 1B [Homo sapiens] 269 9e-72
gi|194248072 heat shock 70kDa protein 1A [Homo sapiens] 269 9e-72
gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens] 267 3e-71
gi|16507237 heat shock 70kDa protein 5 [Homo sapiens] 263 7e-70
gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens] 259 7e-69
gi|13676857 heat shock 70kDa protein 2 [Homo sapiens] 255 1e-67
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 238 2e-62
gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens] 192 9e-49
gi|48928056 heat shock protein 70kDa family member 13 precursor ... 162 1e-39
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 3e-04
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 8e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 42 0.002
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens] 42 0.002
gi|34878904 synaptonemal complex protein 1 [Homo sapiens] 41 0.004
gi|115648142 centrosomal protein 164kDa [Homo sapiens] 40 0.007
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 40 0.009
gi|148746195 trichohyalin [Homo sapiens] 39 0.016
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 39 0.016
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 39 0.021
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 39 0.021
gi|115529449 upstream binding transcription factor, RNA polymera... 39 0.021
gi|115529451 upstream binding transcription factor, RNA polymera... 39 0.021
gi|7657671 upstream binding transcription factor, RNA polymerase... 39 0.021
>gi|42544159 heat shock 105kD [Homo sapiens]
Length = 858
Score = 1718 bits (4450), Expect = 0.0
Identities = 858/858 (100%), Positives = 858/858 (100%)
Query: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA
Sbjct: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM
Sbjct: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN
Sbjct: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL
Sbjct: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK
Sbjct: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
Query: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360
MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK
Sbjct: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360
Query: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420
DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420
Query: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480
SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV
Sbjct: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480
Query: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540
KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT
Sbjct: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540
Query: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600
QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA
Sbjct: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600
Query: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660
NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ
Sbjct: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660
Query: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720
DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG
Sbjct: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720
Query: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780
QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV
Sbjct: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780
Query: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 840
RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH
Sbjct: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPH 840
Query: 841 QNGECYPNEKNSVNMDLD 858
QNGECYPNEKNSVNMDLD
Sbjct: 841 QNGECYPNEKNSVNMDLD 858
>gi|38327039 heat shock 70kDa protein 4 [Homo sapiens]
Length = 840
Score = 1082 bits (2798), Expect = 0.0
Identities = 539/822 (65%), Positives = 652/822 (79%), Gaps = 20/822 (2%)
Query: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
MSVVG+D+G QSCY+AVARAGGIETIANE+SDRCTP+ ISFG KNR+IG AAK+Q I++A
Sbjct: 1 MSVVGIDLGFQSCYVAVARAGGIETIANEYSDRCTPACISFGPKNRSIGAAAKSQVISNA 60
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NTV FKRFHGRAF+DPF++ EK NL+YD+V L G GIKV YM EE F+ EQ+TAM
Sbjct: 61 KNTVQGFKRFHGRAFSDPFVEAEKSNLAYDIVQLPTGLTGIKVTYMEEERNFTTEQVTAM 120
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
LL+KLKETAE+ LKKPV DCV+SVP F+TDAERRSV+DA QI GLNCLRLMN+ TAVAL
Sbjct: 121 LLSKLKETAESVLKKPVVDCVVSVPCFYTDAERRSVMDATQIAGLNCLRLMNETTAVALA 180
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YGIYKQDLP+L+EKPR VVFVDMGHSA+QVS CAFN+GKLKVL TAFD LGG+ FDE L
Sbjct: 181 YGIYKQDLPALEEKPRNVVFVDMGHSAYQVSVCAFNRGKLKVLATAFDTTLGGRKFDEVL 240
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
V HFC EF KYKLD KSKIRALLRL QECEKLKKLMS+N++DLPL+IECFMND DVSG
Sbjct: 241 VNHFCEEFGKKYKLDIKSKIRALLRLSQECEKLKKLMSANASDLPLSIECFMNDVDVSGT 300
Query: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360
MNR +F E+C +LL ++E PL S+LEQT LK ED+ AVEIVGGATRIPAVKE+I+KFFGK
Sbjct: 301 MNRGKFLEMCNDLLARVEPPLRSVLEQTKLKKEDIYAVEIVGGATRIPAVKEKISKFFGK 360
Query: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420
++STTLNADEAV RGCALQCAILSPAFKVREFS+TD VP+PISL WN +E+ EVF
Sbjct: 361 ELSTTLNADEAVTRGCALQCAILSPAFKVREFSITDVVPYPISLRWNSPAEEGSSDCEVF 420
Query: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480
S+NHAAPFSKVLTF R+ PF LEA+YS PQ +PYP+ I +F VQ V+ Q DG S+VKV
Sbjct: 421 SKNHAAPFSKVLTFYRKEPFTLEAYYSSPQDLPYPDPAIAQFSVQKVTPQSDGSSSKVKV 480
Query: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540
KVRVN HGIF++S+AS+VE +EENE E D +N ++ +Q D E
Sbjct: 481 KVRVNVHGIFSVSSASLVEVHKSEENEEPMETD---------QNAKEEEKMQVDQEE--- 528
Query: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600
P V+ QQT P + SEE + A + +KK+DQPP+AKK K+K V+LPIE
Sbjct: 529 -PHVEEQQQQT---PAENKAESEEMETSQAG-SKDKKMDQPPQAKKAKVKTSTVDLPIEN 583
Query: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660
L+WQ+ +++LN+YIE EGKMIMQDKLEKERNDAKNAVEEYVYE RDKL G YEKF+ E
Sbjct: 584 QLLWQIDREMLNLYIENEGKMIMQDKLEKERNDAKNAVEEYVYEMRDKLSGEYEKFVSED 643
Query: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720
D +F L +TE+WLYE+GEDQ KQ YVDKL EL +G P+K+RFQE+EERPK+FEELG
Sbjct: 644 DRNSFTLKLEDTENWLYEDGEDQPKQVYVDKLAELKNLGQPIKIRFQESEERPKLFEELG 703
Query: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780
+++Q Y KI + F+NK+++Y+H+D ++M KVEKS NE MEWMNN +N Q K+SL DPVV
Sbjct: 704 KQIQQYMKIISSFKNKEDQYDHLDAADMTKVEKSTNEAMEWMNNKLNLQNKQSLTMDPVV 763
Query: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIESPKLER---TPNGP 819
+++EI+ KIKEL +TC P++++PKPK+E PK E+ NGP
Sbjct: 764 KSKEIEAKIKELTSTCSPIISKPKPKVEPPKEEQKNAEQNGP 805
>gi|31541941 heat shock 70kDa protein 4-like [Homo sapiens]
Length = 839
Score = 992 bits (2564), Expect = 0.0
Identities = 499/823 (60%), Positives = 624/823 (75%), Gaps = 18/823 (2%)
Query: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
MSVVG+D+G +CYIAVAR+GGIETIANE+SDRCTP+ IS GS+ R IG AAK+Q +T+
Sbjct: 1 MSVVGIDLGFLNCYIAVARSGGIETIANEYSDRCTPACISLGSRTRAIGNAAKSQIVTNV 60
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NT+ FK+ HGR+F+DP +Q E+ L Y+L + NG G+KV Y+ EE F++EQ+T M
Sbjct: 61 RNTIHGFKKLHGRSFDDPIVQTERIRLPYELQKMPNGSAGVKVRYLEEERPFAIEQVTGM 120
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
LL KLKET+EN+LKKPV DCVIS+PSFFTDAERRSV+ AAQ+ GLNCLRLMN+ TAVAL
Sbjct: 121 LLAKLKETSENALKKPVADCVISIPSFFTDAERRSVMAAAQVAGLNCLRLMNETTAVALA 180
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YGIYKQDLP LDEKPR VVF+DMGHSA+QV CAFNKGKLKVL T FDP+LGG+NFDE L
Sbjct: 181 YGIYKQDLPPLDEKPRNVVFIDMGHSAYQVLVCAFNKGKLKVLATTFDPYLGGRNFDEAL 240
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
V++FC EFKTKYK++ K RALLRLYQECEKLKKLMS+N++DLPLNIECFMND DVS K
Sbjct: 241 VDYFCDEFKTKYKINVKENSRALLRLYQECEKLKKLMSANASDLPLNIECFMNDLDVSSK 300
Query: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGK 360
MNR+QFE+LCA LL ++E PL +++EQ +L+ ED+S++EIVGGATRIPAVKE+I KFF K
Sbjct: 301 MNRAQFEQLCASLLARVEPPLKAVMEQANLQREDISSIEIVGGATRIPAVKEQITKFFLK 360
Query: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVF 420
DISTTLNADEAVARGCALQCAILSPAFKVREFS+TD VP+ I+L W ED G EVF
Sbjct: 361 DISTTLNADEAVARGCALQCAILSPAFKVREFSITDLVPYSITLRWKTSFEDGSGECEVF 420
Query: 421 SRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKV 480
+NH APFSKV+TF ++ PFELEAFY++ VPYP+A+IG F +QNV Q DG+ S+VKV
Sbjct: 421 CKNHPAPFSKVITFHKKEPFELEAFYTNLHEVPYPDARIGSFTIQNVFPQSDGDSSKVKV 480
Query: 481 KVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGT 540
KVRVN HGIF++++AS++EK E + S+A ME EN D +Q D E
Sbjct: 481 KVRVNIHGIFSVASASVIEKQNLEGDH--SDAPMETETSFKNENKDNMDKMQVDQEEG-- 536
Query: 541 QPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEA 600
+ A+ T P E+ K A + +++Q KK K+K +++LPI++
Sbjct: 537 --HQKCHAEHT----PEEEIDHTGAKTKSAVSDKQDRLNQ--TLKKGKVK--SIDLPIQS 586
Query: 601 NLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQ 660
+L QLG+DLLN YIE EGKMIMQDKLEKERNDAKNAVEEYVY+FRD+L YEKFI +
Sbjct: 587 SLCRQLGQDLLNSYIENEGKMIMQDKLEKERNDAKNAVEEYVYDFRDRLGTVYEKFITPE 646
Query: 661 DHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELG 720
D +L +TE+WLYE+GEDQ KQ YVDKL+EL K G P+++++ E EERPK +LG
Sbjct: 647 DLSKLSAVLEDTENWLYEDGEDQPKQVYVDKLQELKKYGQPIQMKYMEHEERPKALNDLG 706
Query: 721 QRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVV 780
+++Q K+ +RNKDE+Y+H+D +EM+KVEK +++ M W+N+ MNAQ K SL QDPVV
Sbjct: 707 KKIQLVMKVIEAYRNKDERYDHLDPTEMEKVEKCISDAMSWLNSKMNAQNKLSLTQDPVV 766
Query: 781 RAQEIKTKIKELNNTCEPVVTQPKPKIE----SPKLERTPNGP 819
+ EI K KEL+N C P++ +PKPK E PK NGP
Sbjct: 767 KVSEIVAKSKELDNFCNPIIYKPKPKAEVPEDKPKANSEHNGP 809
>gi|195976805 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 314 bits (805), Expect = 2e-85
Identities = 256/934 (27%), Positives = 437/934 (46%), Gaps = 132/934 (14%)
Query: 1 MSVVGLDVGSQSCYIAVARAG-GIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITH 59
++V+ +D+GS+S +A+ + G +E + N+ S R TP +++ R G +A + I +
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 ANNTVSNFKRFHGRAFNDPFI-----QKEKENLSYDLVPLKNGGVGIKVMYMGEEHL-FS 113
T+ F+ G+ ++P + + + L++D P + V + L FS
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFD--PQRQ-----TVHFQISSQLQFS 145
Query: 114 VEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMND 173
E++ M+L + AE+ ++P+ D VI+VP FF AERR+VL AA++ GL L+L+ND
Sbjct: 146 PEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLIND 205
Query: 174 MTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGK---------LKVLG 224
TA AL+YG++++ ++ + ++F DMG + + + K L++ G
Sbjct: 206 NTATALSYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRG 263
Query: 225 TAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSKIRALLRLYQECEKLKKLMSSN 280
FD LGG + +L E F + K D + RA+ +L +E +LK ++S+N
Sbjct: 264 VGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSAN 323
Query: 281 STDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEI 340
+ D IE M+D D K+ R +FEELCA+L +++ P+ L+ + ++++ V +
Sbjct: 324 A-DHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVIL 382
Query: 341 VGGATRIPAVKERIAKFFGK-DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVP 399
VGGATR+P V+E + K GK ++ +NADEA A G Q A LS AFKV+ F V DAV
Sbjct: 383 VGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVV 442
Query: 400 FPISLIWNHDSEDTEGVHE-------VFSRNHAAPFSKVLTFLRRG-PFELEAFYSDPQG 451
+PI + + + E+ G+H +FSR P KV+TF R F Y D G
Sbjct: 443 YPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGD-LG 501
Query: 452 VPYPEAKIGRFVVQNVSAQK------------DGEKSRVKVKVRVNTHGIFTISTA---- 495
PE + F QN++ K D E +K ++ G+ ++
Sbjct: 502 FLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVF 560
Query: 496 -SMVEKVPTEENEMSSEADMECLNQRPPENPDTDKN----VQQD--------NSEAGTQP 542
++VE EE+ ++ + PD +N VQ++ E G Q
Sbjct: 561 ETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQV 620
Query: 543 QVQTDAQ---QTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPK----------- 588
+++ +A+ + PP PE + + P+ +KA EK+ EA+KP
Sbjct: 621 ELKEEAEAPVEDGSQPPPPE--PKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVA 678
Query: 589 -----------------IKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKER 631
++ + VEL + + L +D L ++ + ++D ++ER
Sbjct: 679 PAPEGEKKQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQER 736
Query: 632 NDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVD 690
A N++E +++E +DKL P Y++ E+ + L+ WL +EG +
Sbjct: 737 EKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKE 796
Query: 691 KLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKK 750
KL EL K+ + R +E ++ P+ L L H + R E E EM
Sbjct: 797 KLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTT 856
Query: 751 VEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVV-----TQPKP 805
+EK +NE W N + QAK + PV+ +++I+ K+ L+ + ++ T+P+P
Sbjct: 857 LEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRP 916
Query: 806 KIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPP 839
+ PK DKN AEPP
Sbjct: 917 R---PK------------------DKNGTRAEPP 929
>gi|5453832 hypoxia up-regulated 1 precursor [Homo sapiens]
Length = 999
Score = 314 bits (805), Expect = 2e-85
Identities = 256/934 (27%), Positives = 437/934 (46%), Gaps = 132/934 (14%)
Query: 1 MSVVGLDVGSQSCYIAVARAG-GIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITH 59
++V+ +D+GS+S +A+ + G +E + N+ S R TP +++ R G +A + I +
Sbjct: 33 LAVMSVDLGSESMKVAIVKPGVPMEIVLNKESRRKTPVIVTLKENERFFGDSAASMAIKN 92
Query: 60 ANNTVSNFKRFHGRAFNDPFI-----QKEKENLSYDLVPLKNGGVGIKVMYMGEEHL-FS 113
T+ F+ G+ ++P + + + L++D P + V + L FS
Sbjct: 93 PKATLRYFQHLLGKQADNPHVALYQARFPEHELTFD--PQRQ-----TVHFQISSQLQFS 145
Query: 114 VEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMND 173
E++ M+L + AE+ ++P+ D VI+VP FF AERR+VL AA++ GL L+L+ND
Sbjct: 146 PEEVLGMVLNYSRSLAEDFAEQPIKDAVITVPVFFNQAERRAVLQAARMAGLKVLQLIND 205
Query: 174 MTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGK---------LKVLG 224
TA AL+YG++++ ++ + ++F DMG + + + K L++ G
Sbjct: 206 NTATALSYGVFRR--KDINTTAQNIMFYDMGSGSTVCTIVTYQMVKTKEAGMQPQLQIRG 263
Query: 225 TAFDPFLGGKNFDEKLVEHFCAEFKTKYK----LDAKSKIRALLRLYQECEKLKKLMSSN 280
FD LGG + +L E F + K D + RA+ +L +E +LK ++S+N
Sbjct: 264 VGFDRTLGGLEMELRLRERLAGLFNEQRKGQRAKDVRENPRAMAKLLREANRLKTVLSAN 323
Query: 281 STDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEI 340
+ D IE M+D D K+ R +FEELCA+L +++ P+ L+ + ++++ V +
Sbjct: 324 A-DHMAQIEGLMDDVDFKAKVTRVEFEELCADLFERVPGPVQQALQSAEMSLDEIEQVIL 382
Query: 341 VGGATRIPAVKERIAKFFGK-DISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVP 399
VGGATR+P V+E + K GK ++ +NADEA A G Q A LS AFKV+ F V DAV
Sbjct: 383 VGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKAFKVKPFVVRDAVV 442
Query: 400 FPISLIWNHDSEDTEGVHE-------VFSRNHAAPFSKVLTFLRRG-PFELEAFYSDPQG 451
+PI + + + E+ G+H +FSR P KV+TF R F Y D G
Sbjct: 443 YPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSHDFNFHINYGD-LG 501
Query: 452 VPYPEAKIGRFVVQNVSAQK------------DGEKSRVKVKVRVNTHGIFTISTA---- 495
PE + F QN++ K D E +K ++ G+ ++
Sbjct: 502 FLGPE-DLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESGVLSLDRVESVF 560
Query: 496 -SMVEKVPTEENEMSSEADMECLNQRPPENPDTDKN----VQQD--------NSEAGTQP 542
++VE EE+ ++ + PD +N VQ++ E G Q
Sbjct: 561 ETLVEDSAEEESTLTKLGNTISSLFGGGTTPDAKENGTDTVQEEEESPAEGSKDEPGEQV 620
Query: 543 QVQTDAQ---QTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPK----------- 588
+++ +A+ + PP PE + + P+ +KA EK+ EA+KP
Sbjct: 621 ELKEEAEAPVEDGSQPPPPE--PKGDATPEGEKATEKENGDKSEAQKPSEKAEAGPEGVA 678
Query: 589 -----------------IKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKER 631
++ + VEL + + L +D L ++ + ++D ++ER
Sbjct: 679 PAPEGEKKQKPARKRRMVEEIGVELVVLD--LPDLPEDKLAQSVQKLQDLTLRDLEKQER 736
Query: 632 NDAKNAVEEYVYEFRDKLCGP-YEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVD 690
A N++E +++E +DKL P Y++ E+ + L+ WL +EG +
Sbjct: 737 EKAANSLEAFIFETQDKLYQPEYQEVSTEEQREEISGKLSAASTWLEDEGVGATTVMLKE 796
Query: 691 KLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKK 750
KL EL K+ + R +E ++ P+ L L H + R E E EM
Sbjct: 797 KLAELRKLCQGLFFRVEERKKWPERLSALDNLLNHSSMFLKGARLIPEMDQIFTEVEMTT 856
Query: 751 VEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVV-----TQPKP 805
+EK +NE W N + QAK + PV+ +++I+ K+ L+ + ++ T+P+P
Sbjct: 857 LEKVINETWAWKNATLAEQAKLPATEKPVLLSKDIEAKMMALDREVQYLLNKAKFTKPRP 916
Query: 806 KIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPP 839
+ PK DKN AEPP
Sbjct: 917 R---PK------------------DKNGTRAEPP 929
>gi|124256496 heat shock 70kDa protein 1-like [Homo sapiens]
Length = 641
Score = 274 bits (701), Expect = 2e-73
Identities = 187/578 (32%), Positives = 297/578 (51%), Gaps = 26/578 (4%)
Query: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
+G+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 9 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNT 68
Query: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
V + KR GR FNDP +Q + + + ++ + G + V Y GE F E+I++M+LT
Sbjct: 69 VFDAKRLIGRKFNDPVVQADMKLWPFQVIN-EGGKPKVLVSYKGENKAFYPEEISSMVLT 127
Query: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
KLKETAE L PVT+ VI+VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 128 KLKETAEAFLGHPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGL 187
Query: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
K + R V+ D+G F VS + G +V TA D LGG++FD +LV H
Sbjct: 188 DKG-----GQGERHVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNRLVSH 242
Query: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
F EFK K+K D RA+ RL CE+ K+ +SS ST L I+ D + R
Sbjct: 243 FVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSS-STQANLEIDSLYEGIDFYTSITR 301
Query: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
++FEELCA+L + P+ L + + + +VGG+TRIP V+ + +F G+D+
Sbjct: 302 ARFEELCADLFRGTLEPVEKALRDAKMDKAKIHDIVLVGGSTRIPKVQRLLQDYFNGRDL 361
Query: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419
+ ++N DEAVA G A+Q AIL + KV++ + D P + L E GV +
Sbjct: 362 NKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLLDVAPLSLGL------ETAGGVMTAL 415
Query: 420 FSRNHAAPFSKV---LTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
RN P + T+ P L Y + + +GRF + + G
Sbjct: 416 IKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFDLTGIPPAPRG-VP 474
Query: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNS 536
+++V ++ +GI ++ +K + N+++ D L++ E D +
Sbjct: 475 QIEVTFDIDANGILNVTA---TDKSTGKVNKITITNDKGRLSKEEIERMVLDAEKYKAED 531
Query: 537 EAGTQPQVQTDAQQTSQSPPSPELTSE--ENKIPDADK 572
E + +A ++ ++ E + KI ++DK
Sbjct: 532 EVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDK 569
Score = 33.9 bits (76), Expect = 0.66
Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 2/99 (2%)
Query: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEK-FICEQDHQ 663
+L K+ + + K +D++++E+ AKNA+E Y + + + K I E D
Sbjct: 511 RLSKEEIERMVLDAEKYKAEDEVQREKIAAKNALESYAFNMKSVVSDEGLKGKISESDKN 570
Query: 664 NFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702
L E WL E + K + K +EL ++ P+
Sbjct: 571 KILDKCNELLSWL-EVNQLAEKDEFDHKRKELEQMCNPI 608
Score = 31.2 bits (69), Expect = 4.3
Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 12/60 (20%)
Query: 743 IDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802
I ES+ K+ NE++ W+ +N A+K E K KEL C P++T+
Sbjct: 564 ISESDKNKILDKCNELLSWLE--VNQLAEKD----------EFDHKRKELEQMCNPIITK 611
>gi|5729877 heat shock 70kDa protein 8 isoform 1 [Homo sapiens]
Length = 646
Score = 271 bits (694), Expect = 1e-72
Identities = 191/610 (31%), Positives = 314/610 (51%), Gaps = 34/610 (5%)
Query: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
VG+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
Query: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
V + KR GR F+D +Q + ++ + +V G ++V Y GE F E++++M+LT
Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPF-MVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
K+KE AE L K VT+ V++VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
K+ + + +++F D+G F VS G +V TA D LGG++FD ++V H
Sbjct: 186 DKK----VGAERNVLIF-DLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
F AEFK K+K D RA+ RL CE+ K+ +SS ST + I+ D + R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGIDFYTSITR 299
Query: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
++FEEL A+L + P+ L L + + +VGG+TRIP +++ + FF GK++
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV- 419
+ ++N DEAVA G A+Q AILS + V++ + D P + + E GV V
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTVL 413
Query: 420 FSRNHAAPFSKVLTFLR---RGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
RN P + TF P L Y + + +G+F + + G
Sbjct: 414 IKRNTTIPTKQTQTFTTYSDNQPGVLIQVYEGERAMTKDNNLLGKFELTGIPPAPRG-VP 472
Query: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMS--------SEADMECLNQRPPENPDTD 528
+++V ++ +GI +S V+K +EN+++ S+ D+E + Q + D
Sbjct: 473 QIEVTFDIDANGILNVSA---VDKSTGKENKITITNDKGRLSKEDIERMVQEAEKYKAED 529
Query: 529 KNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANE--KKVDQPPEAKK 586
+ + S + + + T + ++E+K DK NE +D+ A+K
Sbjct: 530 EKQRDKVSSKNSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINWLDKNQTAEK 589
Query: 587 PKIKVVNVEL 596
+ + EL
Sbjct: 590 EEFEHQQKEL 599
Score = 37.7 bits (86), Expect = 0.046
Identities = 35/163 (21%), Positives = 73/163 (44%), Gaps = 22/163 (13%)
Query: 555 PPSPELTSEENKIPDADK---ANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLL 611
PP+P + D D N VD+ K+ KI + N + +L K+ +
Sbjct: 465 PPAPRGVPQIEVTFDIDANGILNVSAVDKST-GKENKITITNDK--------GRLSKEDI 515
Query: 612 NMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFR-----DKLCGPYEKFICEQDHQNFL 666
++ K +D+ ++++ +KN++E Y + + +KL G I ++D Q L
Sbjct: 516 ERMVQEAEKYKAEDEKQRDKVSSKNSLESYAFNMKATVEDEKLQGK----INDEDKQKIL 571
Query: 667 RLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEA 709
E +WL ++ + K+ + + +EL K+ P+ + ++
Sbjct: 572 DKCNEIINWL-DKNQTAEKEEFEHQQKELEKVCNPIITKLYQS 613
Score = 33.5 bits (75), Expect = 0.86
Identities = 20/100 (20%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 703 KVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWM 762
K + ++ ++R K+ + L+ YA ++ I++ + +K+ NE++ W
Sbjct: 524 KYKAEDEKQRDKVSSK--NSLESYAFNMKATVEDEKLQGKINDEDKQKILDKCNEIINW- 580
Query: 763 NNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802
LD++ +E + + KEL C P++T+
Sbjct: 581 -----------LDKNQTAEKEEFEHQQKELEKVCNPIITK 609
>gi|167466173 heat shock 70kDa protein 1B [Homo sapiens]
Length = 641
Score = 269 bits (687), Expect = 9e-72
Identities = 182/551 (33%), Positives = 285/551 (51%), Gaps = 31/551 (5%)
Query: 2 SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHAN 61
+ +G+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ +
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGG--VGIKVMYMGEEHLFSVEQITA 119
NTV + KR GR F DP +Q + ++ + ++ N G ++V Y GE F E+I++
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI---NDGDKPKVQVSYKGETKAFYPEEISS 121
Query: 120 MLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVAL 179
M+LTK+KE AE L PVT+ VI+VP++F D++R++ DA I GLN LR++N+ TA A+
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
Query: 180 NYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEK 239
YG L + R V+ D+G F VS + G +V TA D LGG++FD +
Sbjct: 182 AYG-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNR 236
Query: 240 LVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSG 299
LV HF EFK K+K D RA+ RL CE+ K+ +SS ST L I+ D
Sbjct: 237 LVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSS-STQASLEIDSLFEGIDFYT 295
Query: 300 KMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF- 358
+ R++FEELC++L + P+ L L + + +VGG+TRIP V++ + FF
Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355
Query: 359 GKDISTTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV 416
G+D++ ++N DEAVA G A+Q AIL + V++ + D P + L E GV
Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGL------ETAGGV 409
Query: 417 -HEVFSRNHAAPFSKV---LTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKD 472
+ RN P + T+ P L Y + + +GRF + +
Sbjct: 410 MTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPR 469
Query: 473 GEKSRVKVKVRVNTHGIFTI-----STASMVEKVPTEENEMSSEADMECLNQRPPENPDT 527
G +++V ++ +GI + ST + T + S+ ++E + Q E
Sbjct: 470 G-VPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQE-AEKYKA 527
Query: 528 DKNVQQDNSEA 538
+ VQ++ A
Sbjct: 528 EDEVQRERVSA 538
Score = 35.8 bits (81), Expect = 0.17
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEK-FICEQDHQ 663
+L K+ + ++ K +D++++ER AKNA+E Y + + + K I E D +
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
Query: 664 NFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702
L E WL + K + K +EL ++ P+
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
Score = 31.6 bits (70), Expect = 3.3
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 12/59 (20%)
Query: 743 IDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVT 801
I E++ KKV EV+ W LD + + E + K KEL C P+++
Sbjct: 562 ISEADKKKVLDKCQEVISW------------LDANTLAEKDEFEHKRKELEQVCNPIIS 608
>gi|194248072 heat shock 70kDa protein 1A [Homo sapiens]
Length = 641
Score = 269 bits (687), Expect = 9e-72
Identities = 182/551 (33%), Positives = 285/551 (51%), Gaps = 31/551 (5%)
Query: 2 SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHAN 61
+ +G+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ +
Sbjct: 5 AAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVALNPQ 64
Query: 62 NTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGG--VGIKVMYMGEEHLFSVEQITA 119
NTV + KR GR F DP +Q + ++ + ++ N G ++V Y GE F E+I++
Sbjct: 65 NTVFDAKRLIGRKFGDPVVQSDMKHWPFQVI---NDGDKPKVQVSYKGETKAFYPEEISS 121
Query: 120 MLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVAL 179
M+LTK+KE AE L PVT+ VI+VP++F D++R++ DA I GLN LR++N+ TA A+
Sbjct: 122 MVLTKMKEIAEAYLGYPVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAI 181
Query: 180 NYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEK 239
YG L + R V+ D+G F VS + G +V TA D LGG++FD +
Sbjct: 182 AYG-----LDRTGKGERNVLIFDLGGGTFDVSILTIDDGIFEVKATAGDTHLGGEDFDNR 236
Query: 240 LVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSG 299
LV HF EFK K+K D RA+ RL CE+ K+ +SS ST L I+ D
Sbjct: 237 LVNHFVEEFKRKHKKDISQNKRAVRRLRTACERAKRTLSS-STQASLEIDSLFEGIDFYT 295
Query: 300 KMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF- 358
+ R++FEELC++L + P+ L L + + +VGG+TRIP V++ + FF
Sbjct: 296 SITRARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDLVLVGGSTRIPKVQKLLQDFFN 355
Query: 359 GKDISTTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV 416
G+D++ ++N DEAVA G A+Q AIL + V++ + D P + L E GV
Sbjct: 356 GRDLNKSINPDEAVAYGAAVQAAILMGDKSENVQDLLLLDVAPLSLGL------ETAGGV 409
Query: 417 -HEVFSRNHAAPFSKV---LTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKD 472
+ RN P + T+ P L Y + + +GRF + +
Sbjct: 410 MTALIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTKDNNLLGRFELSGIPPAPR 469
Query: 473 GEKSRVKVKVRVNTHGIFTI-----STASMVEKVPTEENEMSSEADMECLNQRPPENPDT 527
G +++V ++ +GI + ST + T + S+ ++E + Q E
Sbjct: 470 G-VPQIEVTFDIDANGILNVTATDKSTGKANKITITNDKGRLSKEEIERMVQE-AEKYKA 527
Query: 528 DKNVQQDNSEA 538
+ VQ++ A
Sbjct: 528 EDEVQRERVSA 538
Score = 35.8 bits (81), Expect = 0.17
Identities = 25/99 (25%), Positives = 46/99 (46%), Gaps = 2/99 (2%)
Query: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEK-FICEQDHQ 663
+L K+ + ++ K +D++++ER AKNA+E Y + + + K I E D +
Sbjct: 509 RLSKEEIERMVQEAEKYKAEDEVQRERVSAKNALESYAFNMKSAVEDEGLKGKISEADKK 568
Query: 664 NFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702
L E WL + K + K +EL ++ P+
Sbjct: 569 KVLDKCQEVISWL-DANTLAEKDEFEHKRKELEQVCNPI 606
Score = 31.6 bits (70), Expect = 3.3
Identities = 17/59 (28%), Positives = 26/59 (44%), Gaps = 12/59 (20%)
Query: 743 IDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVT 801
I E++ KKV EV+ W LD + + E + K KEL C P+++
Sbjct: 562 ISEADKKKVLDKCQEVISW------------LDANTLAEKDEFEHKRKELEQVCNPIIS 608
>gi|34419635 heat shock 70kDa protein 6 (HSP70B') [Homo sapiens]
Length = 643
Score = 267 bits (683), Expect = 3e-71
Identities = 167/497 (33%), Positives = 269/497 (54%), Gaps = 21/497 (4%)
Query: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
VG+D+G+ + V + G +E +AN+ +R TPS ++F R +G AAK+Q + +NT
Sbjct: 9 VGIDLGTTYSCVGVFQQGRVEILANDQGNRTTPSYVAFTDTERLVGDAAKSQAALNPHNT 68
Query: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
V + KR GR F D +Q + ++ + +V + G ++V Y GE+ F E+I++M+L+
Sbjct: 69 VFDAKRLIGRKFADTTVQSDMKHWPFRVVS-EGGKPKVRVCYRGEDKTFYPEEISSMVLS 127
Query: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
K+KETAE L +PV VI+VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 128 KMKETAEAYLGQPVKHAVITVPAYFNDSQRQATKDAGAIAGLNVLRIINEPTAAAIAYGL 187
Query: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
++ R V+ D+G F VS + + G +V TA D LGG++FD +LV H
Sbjct: 188 DRRGAGE-----RNVLIFDLGGGTFDVSVLSIDAGVFEVKATAGDTHLGGEDFDNRLVNH 242
Query: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
F EF+ K+ D RAL RL CE+ K+ +SS ST L I+ D + R
Sbjct: 243 FMEEFRRKHGKDLSGNKRALRRLRTACERAKRTLSS-STQATLEIDSLFEGVDFYTSITR 301
Query: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
++FEELC++L + P+ L L + V +VGG+TRIP V++ + FF GK++
Sbjct: 302 ARFEELCSDLFRSTLEPVEKALRDAKLDKAQIHDVVLVGGSTRIPKVQKLLQDFFNGKEL 361
Query: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419
+ ++N DEAVA G A+Q A+L KV++ + D P + L E GV +
Sbjct: 362 NKSINPDEAVAYGAAVQAAVLMGDKCEKVQDLLLLDVAPLSLGL------ETAGGVMTTL 415
Query: 420 FSRNHAAPFSKVLTFLRRGPFELEAF---YSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
RN P + TF + F Y + + +GRF + + G
Sbjct: 416 IQRNATIPTKQTQTFTTYSDNQPGVFIQVYEGERAMTKDNNLLGRFELSGIPPAPRG-VP 474
Query: 477 RVKVKVRVNTHGIFTIS 493
+++V ++ +GI +++
Sbjct: 475 QIEVTFDIDANGILSVT 491
>gi|16507237 heat shock 70kDa protein 5 [Homo sapiens]
Length = 654
Score = 263 bits (671), Expect = 7e-70
Identities = 184/595 (30%), Positives = 310/595 (52%), Gaps = 30/595 (5%)
Query: 2 SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKN-RTIGVAAKNQQITHA 60
+VVG+D+G+ + V + G +E IAN+ +R TPS ++F + R IG AAKNQ ++
Sbjct: 29 TVVGIDLGTTYSCVGVFKNGRVEIIANDQGNRITPSYVAFTPEGERLIGDAAKNQLTSNP 88
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NTV + KR GR +NDP +Q++ + L + +V K + G+ F+ E+I+AM
Sbjct: 89 ENTVFDAKRLIGRTWNDPSVQQDIKFLPFKVVEKKTKPYIQVDIGGGQTKTFAPEEISAM 148
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
+LTK+KETAE L K VT V++VP++F DA+R++ DA I GLN +R++N+ TA A+
Sbjct: 149 VLTKMKETAEAYLGKKVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVMRIINEPTAAAIA 208
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YG+ K+ + + I+VF D+G F VS + G +V+ T D LGG++FD+++
Sbjct: 209 YGLDKR-----EGEKNILVF-DLGGGTFDVSLLTIDNGVFEVVATNGDTHLGGEDFDQRV 262
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGK 300
+EHF +K K D + RA+ +L +E EK K+ +SS + IE F +D S
Sbjct: 263 MEHFIKLYKKKTGKDVRKDNRAVQKLRREVEKAKRALSSQH-QARIEIESFYEGEDFSET 321
Query: 301 MNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-G 359
+ R++FEEL +L + P+ +LE + LK D+ + +VGG+TRIP +++ + +FF G
Sbjct: 322 LTRAKFEELNMDLFRSTMKPVQKVLEDSDLKKSDIDEIVLVGGSTRIPKIQQLVKEFFNG 381
Query: 360 KDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HE 418
K+ S +N DEAVA G A+Q +LS + + D P + + E GV +
Sbjct: 382 KEPSRGINPDEAVAYGAAVQAGVLSGDQDTGDLVLLDVCPLTLGI------ETVGGVMTK 435
Query: 419 VFSRNHAAPFSKVLTFLRRG---PFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEK 475
+ RN P K F P Y + + +G F + + G
Sbjct: 436 LIPRNTVVPTKKSQIFSTASDNQPTVTIKVYEGERPLTKDNHLLGTFDLTGIPPAPRG-V 494
Query: 476 SRVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDN 535
+++V ++ +GI ++ +K +N+++ D N+ PE + N +
Sbjct: 495 PQIEVTFEIDVNGILRVTAE---DKGTGNKNKITITNDQ---NRLTPEEIERMVNDAEKF 548
Query: 536 SEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIK 590
+E + + + D + +S S +N+I D +K K + E + ++
Sbjct: 549 AEEDKKLKERIDTRNELES----YAYSLKNQIGDKEKLGGKLSSEDKETMEKAVE 599
Score = 39.3 bits (90), Expect = 0.016
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 5/102 (4%)
Query: 620 KMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKF---ICEQDHQNFLRLLTETEDWL 676
K +DK KER D +N +E Y Y ++++ G EK + +D + + + E +WL
Sbjct: 547 KFAEEDKKLKERIDTRNELESYAYSLKNQI-GDKEKLGGKLSSEDKETMEKAVEEKIEWL 605
Query: 677 YEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEE 718
E +D + + K +EL +I P+ + + P EE
Sbjct: 606 -ESHQDADIEDFKAKKKELEEIVQPIISKLYGSAGPPPTGEE 646
Score = 33.9 bits (76), Expect = 0.66
Identities = 23/97 (23%), Positives = 46/97 (47%), Gaps = 15/97 (15%)
Query: 709 AEERPKMFEELGQR--LQHYA-KIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNV 765
AEE K+ E + R L+ YA + +K++ + + + +EK+V E +EW+ +
Sbjct: 549 AEEDKKLKERIDTRNELESYAYSLKNQIGDKEKLGGKLSSEDKETMEKAVEEKIEWLESH 608
Query: 766 MNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQ 802
+A ++ K K KEL +P++++
Sbjct: 609 QDAD------------IEDFKAKKKELEEIVQPIISK 633
>gi|24234686 heat shock 70kDa protein 8 isoform 2 [Homo sapiens]
Length = 493
Score = 259 bits (662), Expect = 7e-69
Identities = 159/435 (36%), Positives = 246/435 (56%), Gaps = 17/435 (3%)
Query: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
VG+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 7 VGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 66
Query: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
V + KR GR F+D +Q + ++ + +V G ++V Y GE F E++++M+LT
Sbjct: 67 VFDAKRLIGRRFDDAVVQSDMKHWPF-MVVNDAGRPKVQVEYKGETKSFYPEEVSSMVLT 125
Query: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
K+KE AE L K VT+ V++VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 126 KMKEIAEAYLGKTVTNAVVTVPAYFNDSQRQATKDAGTIAGLNVLRIINEPTAAAIAYGL 185
Query: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
K+ + + +++F D+G F VS G +V TA D LGG++FD ++V H
Sbjct: 186 DKK----VGAERNVLIF-DLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVNH 240
Query: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
F AEFK K+K D RA+ RL CE+ K+ +SS ST + I+ D + R
Sbjct: 241 FIAEFKRKHKKDISENKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGIDFYTSITR 299
Query: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
++FEEL A+L + P+ L L + + +VGG+TRIP +++ + FF GK++
Sbjct: 300 ARFEELNADLFRGTLDPVEKALRDAKLDKSQIHDIVLVGGSTRIPKIQKLLQDFFNGKEL 359
Query: 363 STTLNADEAVARGCALQCAILS--PAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEV- 419
+ ++N DEAVA G A+Q AILS + V++ + D P + + E GV V
Sbjct: 360 NKSINPDEAVAYGAAVQAAILSGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTVL 413
Query: 420 FSRNHAAPFSKVLTF 434
RN P + TF
Sbjct: 414 IKRNTTIPTKQTQTF 428
>gi|13676857 heat shock 70kDa protein 2 [Homo sapiens]
Length = 639
Score = 255 bits (652), Expect = 1e-67
Identities = 171/537 (31%), Positives = 280/537 (52%), Gaps = 27/537 (5%)
Query: 4 VGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNT 63
+G+D+G+ + V + G +E IAN+ +R TPS ++F R IG AAKNQ + NT
Sbjct: 8 IGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPTNT 67
Query: 64 VSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLT 123
+ + KR GR F D +Q + ++ + +V + G ++V Y GE F E+I++M+LT
Sbjct: 68 IFDAKRLIGRKFEDATVQSDMKHWPFRVVS-EGGKPKVQVEYKGETKTFFPEEISSMVLT 126
Query: 124 KLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGI 183
K+KE AE L V VI+VP++F D++R++ DA I GLN LR++N+ TA A+ YG+
Sbjct: 127 KMKEIAEAYLGGKVHSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAAAIAYGL 186
Query: 184 YKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEH 243
K+ ++ V+ D+G F VS G +V TA D LGG++FD ++V H
Sbjct: 187 DKKGCAGGEKN---VLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRMVSH 243
Query: 244 FCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNR 303
EFK K+K D RA+ RL CE+ K+ +SS ST + I+ D + R
Sbjct: 244 LAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSS-STQASIEIDSLYEGVDFYTSITR 302
Query: 304 SQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFF-GKDI 362
++FEEL A+L + P+ L L + + +VGG+TRIP +++ + FF GK++
Sbjct: 303 ARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGKEL 362
Query: 363 STTLNADEAVARGCALQCAIL--SPAFKVREFSVTDAVPFPISLIWNHDSEDTEGV-HEV 419
+ ++N DEAVA G A+Q AIL + V++ + D P + + E GV +
Sbjct: 363 NKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGI------ETAGGVMTPL 416
Query: 420 FSRNHAAPFSKVLTFLRRGPFE---LEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKS 476
RN P + TF + L Y + + +G+F + + G
Sbjct: 417 IKRNTTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRG-VP 475
Query: 477 RVKVKVRVNTHGIFTISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQ 533
+++V ++ +GI ++ A +K +EN+++ D L++ D D+ VQ+
Sbjct: 476 QIEVTFDIDANGILNVTAA---DKSTGKENKITITNDKGRLSK-----DDIDRMVQE 524
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/103 (28%), Positives = 49/103 (47%), Gaps = 10/103 (9%)
Query: 605 QLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFR-----DKLCGPYEKFICE 659
+L KD ++ ++ + +D+ ++R AKNA+E Y Y + +KL G I E
Sbjct: 512 RLSKDDIDRMVQEAERYKSEDEANRDRVAAKNALESYTYNIKQTVEDEKLRGK----ISE 567
Query: 660 QDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPV 702
QD L E +WL + + K Y K +EL ++ P+
Sbjct: 568 QDKNKILDKCQEVINWL-DRNQMAEKDEYEHKQKELERVCNPI 609
Score = 30.8 bits (68), Expect = 5.6
Identities = 18/68 (26%), Positives = 30/68 (44%), Gaps = 13/68 (19%)
Query: 736 KDEKYN-HIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNN 794
+DEK I E + K+ EV+ W LD++ + E + K KEL
Sbjct: 557 EDEKLRGKISEQDKNKILDKCQEVINW------------LDRNQMAEKDEYEHKQKELER 604
Query: 795 TCEPVVTQ 802
C P++++
Sbjct: 605 VCNPIISK 612
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 238 bits (607), Expect = 2e-62
Identities = 169/582 (29%), Positives = 287/582 (49%), Gaps = 36/582 (6%)
Query: 2 SVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKN-RTIGVAAKNQQITHA 60
+VVG+D+G+ + +AV + + N R TPSV++F + R +G+ AK Q +T+
Sbjct: 54 AVVGIDLGTTNSCVAVMEGKQAKVLENAEGARTTPSVVAFTADGERLVGMPAKRQAVTNP 113
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NNT KR GR ++DP +QK+ +N+ + +V NG ++ L+S QI A
Sbjct: 114 NNTFYATKRLIGRRYDDPEVQKDIKNVPFKIVRASNGDAWVEA----HGKLYSPSQIGAF 169
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
+L K+KETAEN L + VI+VP++F D++R++ DA QI GLN LR++N+ TA AL
Sbjct: 170 VLMKMKETAENYLGHTAKNAVITVPAYFNDSQRQATKDAGQISGLNVLRVINEPTAAALA 229
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YG+ K + +++ D+G F +S KG +V T D FLGG++FD+ L
Sbjct: 230 YGLDKSE-------DKVIAVYDLGGGTFDISILEIQKGVFEVKSTNGDTFLGGEDFDQAL 282
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLK-KLMSSNSTD--LPLNIECFMNDKDV 297
+ H EFK + +D AL R+ + EK K +L SS TD LP K +
Sbjct: 283 LRHIVKEFKRETGVDLTKDNMALQRVREAAEKAKCELSSSVQTDINLPYLTMDSSGPKHL 342
Query: 298 SGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKF 357
+ K+ R+QFE + +L+++ P ++ + D+ V +VGG TR+P V++ +
Sbjct: 343 NMKLTRAQFEGIVTDLIRRTIAPCQKAMQDAEVSKSDIGEVILVGGMTRMPKVQQTVQDL 402
Query: 358 FGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVH 417
FG+ S +N DEAVA G A+Q +L A V + + D P + + E GV
Sbjct: 403 FGRAPSKAVNPDEAVAIGAAIQGGVL--AGDVTDVLLLDVTPLSLGI------ETLGGVF 454
Query: 418 -EVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQG---VPYPEAKIGRFVVQNVSAQKDG 473
++ +RN P K F + + QG + +G+F + + G
Sbjct: 455 TKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLIGIPPAPRG 514
Query: 474 EKSRVKVKVRVNTHGIFTIST----ASMVEKVPTEENEMSSEADMECLNQRPPENPDTDK 529
+++V ++ +GI +S +++ + + S+ D+E + + + + D+
Sbjct: 515 -VPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDR 573
Query: 530 ----NVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKI 567
V+ N G +T ++ P+ E + +I
Sbjct: 574 RKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLKEEI 615
>gi|82880658 heat shock 70kDa protein 14 isoform 1 [Homo sapiens]
Length = 509
Score = 192 bits (489), Expect = 9e-49
Identities = 137/485 (28%), Positives = 240/485 (49%), Gaps = 25/485 (5%)
Query: 1 MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
M+ +G+ +G S +AV + G +AN+ DR TP+V+++ +G+AAK +I +
Sbjct: 1 MAAIGVHLGCTSACVAVYKDGRAGVVANDAGDRVTPAVVAYSENEEIVGLAAKQSRIRNI 60
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
+NTV K+ GR+ +DP QK S LV KNG + ++ E + E + +
Sbjct: 61 SNTVMKVKQILGRSSSDPQAQKYIAE-SKCLVIEKNGKLRYEIDTGEETKFVNPEDVARL 119
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
+ +K+KETA + L D VI+VP F + ++ ++ +AA+ G N LRL+++ +A L
Sbjct: 120 IFSKMKETAHSVLGSDANDVVITVPFDFGEKQKNALGEAARAAGFNVLRLIHEPSAALLA 179
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YGI QD P+ K I+VF +G ++ +S N G +VL T D +GG +F E L
Sbjct: 180 YGI-GQDSPT--GKSNILVF-KLGGTSLSLSVMEVNSGIYRVLSTNTDDNIGGAHFTETL 235
Query: 241 VEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMND----KD 296
++ +EF+ +K D + RA+++L E K +S+ + CF++ +D
Sbjct: 236 AQYLASEFQRSFKHDVRGNARAMMKLTNSAEVAKHSLSTLG-----SANCFLDSLYEGQD 290
Query: 297 VSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAK 356
++R++FE LC+ L K + LL+Q +D++ V + GG++RIP +++ I
Sbjct: 291 FDCNVSRARFELLCSPLFNKCIEAIRGLLDQNGFTADDINKVVLCGGSSRIPKLQQLIKD 350
Query: 357 FF-GKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPIS----LIWNHDSE 411
F ++ ++ DE + G A++ IL V D++ S L+ D
Sbjct: 351 LFPAVELLNSIPPDEVIPIGAAIEAGIL---IGKENLLVEDSLMIECSARDILVKGVDES 407
Query: 412 DTEGVHEVFSRNHAAPFSKVLTFLRRGPFE---LEAFYSDPQGVPYPEAKIGRFVVQNVS 468
+F P + T G LE + SD + E K + V+Q++
Sbjct: 408 GASRFTVLFPSGTPLPARRQHTLQAPGSISSVCLELYESDGKNSAKEETKFAQVVLQDLD 467
Query: 469 AQKDG 473
+++G
Sbjct: 468 KKENG 472
>gi|48928056 heat shock protein 70kDa family member 13 precursor
[Homo sapiens]
Length = 471
Score = 162 bits (410), Expect = 1e-39
Identities = 121/423 (28%), Positives = 206/423 (48%), Gaps = 52/423 (12%)
Query: 3 VVGLDVGSQSCYIAV--ARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHA 60
V+G+D+G+ C + V G ++ I +E PS++SF + +G + ++
Sbjct: 33 VIGIDLGTTYCSVGVFFPGTGKVKVIPDENGHISIPSMVSFTDNDVYVGYESVELADSNP 92
Query: 61 NNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAM 120
NT+ + KRF G+ F ++ E + ++ KNG V V E S E + +
Sbjct: 93 QNTIYDAKRFIGKIFTAEELEAEIGRYPFKVLN-KNGMVEFSVT-SNETITVSPEYVGSR 150
Query: 121 LLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALN 180
LL KLKE AE L PV + VISVP+ F +R S ++AA + GL LR++N+ TA A+
Sbjct: 151 LLLKLKEMAEAYLGMPVANAVISVPAEFDLKQRNSTIEAANLAGLKILRVINEPTAAAMA 210
Query: 181 YGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKL 240
YG++K D+ V+ +D+G VS G + + LGG++F+++L
Sbjct: 211 YGLHKADVFH-------VLVIDLGGGTLDVSLLNKQGGMFLTRAMSGNNKLGGQDFNQRL 263
Query: 241 VEHFCAEFKTKYKL------------DAKSKIRALLRLYQEC---------EKLKKLMSS 279
+++ + Y A ++ L L+Q E+ +K S
Sbjct: 264 LQYLYKQIYQTYGFVPSRKEEIHRLRQAVEMVKLNLTLHQSAQLSVLLTVEEQDRKEPHS 323
Query: 280 NSTDLPLNIECFMNDKDVSG--------------------KMNRSQFEELCAELLQKIEV 319
+ T+LP + +D V+ +++R F+ L +L QKI V
Sbjct: 324 SDTELPKDKLSSADDHRVNSGFGRGLSDKKSGESQVLFETEISRKLFDTLNEDLFQKILV 383
Query: 320 PLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQ 379
P+ +L++ HL+ ++ V +VGG+TRIP +++ I +FFGKD +T+++ D AV G A+Q
Sbjct: 384 PIQQVLKEGHLEKTEIDEVVLVGGSTRIPRIRQVIQEFFGKDPNTSVDPDLAVVTGVAIQ 443
Query: 380 CAI 382
I
Sbjct: 444 AGI 446
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/245 (22%), Positives = 108/245 (44%), Gaps = 21/245 (8%)
Query: 542 PQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEAN 601
PQVQT+ Q EL +E KI K EK Q ++ + K+ E
Sbjct: 263 PQVQTNTLQEEMWRQEEELREQEKKI---RKQEEKMWRQEERLREQEGKMREQE-----E 314
Query: 602 LVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQD 661
+W+ K L E E ++ Q+K +E+ + + EE + E +K+ EK + EQ+
Sbjct: 315 KMWRQEKRLR----EQEKELREQEKELREQKELREQ-EEQMQEQEEKMWEQEEK-MREQE 368
Query: 662 HQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQ 721
+ + + E W E+ + +Q D+ E + + ++ + + E+ KM+E++ +
Sbjct: 369 EKMWRQ---EERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425
Query: 722 RLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVR 781
+ + + +D++ +E +++ EK + E E M Q +K Q+ +
Sbjct: 426 MREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE----TMREQEEKMQKQEENMW 481
Query: 782 AQEIK 786
QE K
Sbjct: 482 EQEEK 486
Score = 36.6 bits (83), Expect = 0.10
Identities = 43/215 (20%), Positives = 102/215 (47%), Gaps = 16/215 (7%)
Query: 623 MQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEGED 682
MQ++ +K R+ + EE R+K E+ + EQ+ + + + E+ ++E+ E
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEK-----MQKQEENMWEQEEK 486
Query: 683 QAKQAYVDKLEELMKIGTPVKVRFQEA-----EERPKMFEEL-GQRLQHYAKIAADFRNK 736
+ +Q + + +E K+ K++ QE EE+ + EE+ GQ + + + + +
Sbjct: 487 EWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ---EKMRE 541
Query: 737 DEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTC 796
E E +M+ E+ + + E M Q KK+ DQ+ +R +E + ++
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREE 601
Query: 797 EPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDK 831
E ++ + + K++ + + + ++EE ++++
Sbjct: 602 EEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQ 636
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 43.5 bits (101), Expect = 8e-04
Identities = 74/347 (21%), Positives = 140/347 (40%), Gaps = 45/347 (12%)
Query: 499 EKVPTEENEMSSEADMECLNQRPPENPDT---DKNVQQDNSEAGTQPQVQTDAQ------ 549
EK+ +E M + + E QR PE + + +Q+ + Q + D +
Sbjct: 413 EKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQE 472
Query: 550 -----QTSQSPPSPELTSEENKIPDADKA---NEKKVDQPPEAKKPKIKVVNVELPIEAN 601
Q ++ +E K+ D ++ E+++ + E + K + + E
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMR-----EQK 527
Query: 602 LVWQLGKDLLNMYIETEGKMIMQDKLEK--------ERNDAKNAVEEYVYEFRDKLCGPY 653
+WQ + + E + D+ EK ER EE + E +K+
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 654 EKFICEQDHQNFLR--LLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEE 711
EK + EQ+ + + + + E E+ ++E+ E +Q DK++E ++ + + QE EE
Sbjct: 588 EK-MREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 712 RPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEK--SVNEVMEWMNNVMNAQ 769
KM+E+ + + K+ R ++EK +E ++ EK E M M Q
Sbjct: 647 --KMWEQEEKMREQEEKM----REQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 770 AKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTP 816
+K Q+ + QE K +E E + K K++ ER P
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQ----ERLP 743
Score = 41.6 bits (96), Expect = 0.003
Identities = 51/254 (20%), Positives = 114/254 (44%), Gaps = 25/254 (9%)
Query: 542 PQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEAN 601
PQVQT+ Q EL +E KI ++ ++ ++ E ++ K++ ++ +
Sbjct: 225 PQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLRE-QEGKMREQEEKMRRQEK 283
Query: 602 LVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQD 661
+ + K+L + K + + K +E+ + EE ++E +K+ EK +++
Sbjct: 284 RLREQEKEL-----REQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338
Query: 662 HQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQ 721
W E+ + +Q D+ E + + ++ + + E+ KM+E+ +
Sbjct: 339 RL-----------WEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQ-EE 386
Query: 722 RLQHYAKIAADFR--NKDEKYNHIDESEMKKVEKSV--NEVMEWMNNVMNAQAKKSLDQD 777
++Q +I + ++E+ E +M+K E+++ E EW + Q +K +Q+
Sbjct: 387 KMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQE 446
Query: 778 PVVRAQEIKTKIKE 791
+ QE + KI E
Sbjct: 447 ---KMQEQEEKIWE 457
Score = 34.7 bits (78), Expect = 0.39
Identities = 50/305 (16%), Positives = 135/305 (44%), Gaps = 18/305 (5%)
Query: 499 EKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSP 558
E++ +E +M + E + ++ + +K +++ E Q +++ +Q +
Sbjct: 262 ERLREQEGKMREQE--EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQ--EE 317
Query: 559 ELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNM----- 613
++ +E K+ + ++ ++ ++ E +K +++ ++ + +W+ + L
Sbjct: 318 KMWEQEEKMREQEEKMWRQEERLWEQEK-QMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 614 ----YIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLL 669
E E KM ++++ +ER EE + E +K+ E +++ + + L
Sbjct: 377 EQEKMWEQEEKMQEEERI-REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRL 435
Query: 670 TETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKI 729
E ++ L+E+ + Q ++ + + EE ++ + + ++ + KM E+ Q + K+
Sbjct: 436 PEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM 495
Query: 730 AADFR---NKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIK 786
+ +++E+ DE +K E+ + W + KK+ +Q+ QE K
Sbjct: 496 RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEK 555
Query: 787 TKIKE 791
+ +E
Sbjct: 556 MREEE 560
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 42.4 bits (98), Expect = 0.002
Identities = 73/317 (23%), Positives = 127/317 (40%), Gaps = 41/317 (12%)
Query: 517 LNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPEL--TSEENKIPD----- 569
L +PP+ PD+ + A ++ +PP P L T EE K P
Sbjct: 8930 LELKPPDIPDSRVPIPTMPIRAVPPEEIPPVV-----APPIPLLLPTPEEKKPPPKRIEV 8984
Query: 570 ---ADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIM--- 623
A K + KKV P+ P+ ++V + P L+ +++++ + E IM
Sbjct: 8985 TKKAVKKDAKKVVAKPKEMTPREEIVK-KPPPPTTLIPAKAPEIIDVSSKAEEVKIMTIT 9043
Query: 624 -QDKLEKERN---DAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEE 679
+ +++KE+ + K AV + F + PY++ E + F + E D YEE
Sbjct: 9044 RKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEE 9103
Query: 680 GEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEK 739
+ +AK+ ++ EE + G QE ER + ++E + + + + + E
Sbjct: 9104 IKVEAKKEVHEEWEEDFEEG-------QEYYEREEGYDEGEEEWEEAYQEREVIQVQKEV 9156
Query: 740 YNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPV 799
Y +ES +KV V E A + + PV+ E ++ E
Sbjct: 9157 Y---EESHERKVPAKVPE--------KKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTK 9205
Query: 800 VTQPKPKIESPKLERTP 816
V + KI K RTP
Sbjct: 9206 VPEVSKKIVPQKPSRTP 9222
Score = 32.7 bits (73), Expect = 1.5
Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 4/143 (2%)
Query: 449 PQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENEM 508
P P + K F ++ + +K EK +V KV + + + + +P + E
Sbjct: 10885 PPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKV-PGGEKKVRKLLPERKPEP 10943
Query: 509 SSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQV-QTDAQQTSQSPPSPELTSEENKI 567
E ++ + ++ PE + + V+ E +P V + + + P +T E KI
Sbjct: 10944 KEEVVLKSVLRKRPE--EEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKI 11001
Query: 568 PDADKANEKKVDQPPEAKKPKIK 590
P+ K E K P A +PK K
Sbjct: 11002 PEPTKVPEIKPAIPLPAPEPKPK 11024
>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
Length = 1411
Score = 42.4 bits (98), Expect = 0.002
Identities = 71/325 (21%), Positives = 135/325 (41%), Gaps = 49/325 (15%)
Query: 509 SSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPE---LTSEEN 565
+ E + LNQ +N + V Q + Q + AQ+ + L + ++
Sbjct: 555 AGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQD 614
Query: 566 KIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDL--------LNMYIET 617
++ + + + Q E+K+ KV +++ I+A L + L +++T
Sbjct: 615 RVLSLETSVNELNSQLNESKE---KVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDT 671
Query: 618 EGKMIMQDKLEKERNDAKNAVEEYVYEFRDKL--CGPYEKFICEQDHQNFLRLLTETEDW 675
+ +QDK ++E N +++ + +DK C E + E + +L L +TE
Sbjct: 672 -AQNALQDK-QQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYK-EKYLSLEQKTE-- 726
Query: 676 LYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKM-------FEELGQRLQHYAK 728
E E Q K+ D LE + + Q+ +++ ++ EL ++L+ +
Sbjct: 727 ---ELEGQIKKLEADSLE----VKASKEQALQDLQQQRQLNTDLELRATELSKQLEMEKE 779
Query: 729 IAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTK 788
I + R +K + ES +K+ K E K+ L QD +QE K +
Sbjct: 780 IVSSTRLDLQKKSEALESIKQKLTKQEEE-------------KQILKQDFETLSQETKIQ 826
Query: 789 IKELNNTCEPVVTQ-PKPKIESPKL 812
+ELNN + VT+ K K+E L
Sbjct: 827 HEELNNRIQTTVTELQKVKMEKEAL 851
>gi|34878904 synaptonemal complex protein 1 [Homo sapiens]
Length = 976
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/296 (20%), Positives = 124/296 (41%), Gaps = 40/296 (13%)
Query: 559 ELTSEENKIPDADKANEKKVDQPPEAK-KPKIKVVNVELPIEANLVWQLGKDLLNMYIET 617
++T +ENK+ D E+ D+ + + K K++ N++ IE L K+L ++ +
Sbjct: 274 QITEKENKMKDLTFLLEESRDKVNQLEEKTKLQSENLKQSIEKQ--HHLTKELEDIKVSL 331
Query: 618 EGKMIMQDKLEKERNDAKNAVEEYVYEFRDKL-------------CGPYEKFICEQDHQN 664
+ + Q LE++ A + + E ++ +E +C
Sbjct: 332 QRSVSTQKALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCS----- 386
Query: 665 FLRLLTETEDWLYEEGEDQAK------QAYVDKLEELMKIGTPVKVRFQEAEERPKMFEE 718
L L TE E+ EDQ K Q +LEE+ K+ +V +E ++ E
Sbjct: 387 -LEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKET 445
Query: 719 LGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLD-QD 777
L + + KIA + + +++ + ++ EK V+++ + + ++ S + +D
Sbjct: 446 LLYENKQFEKIAEELKGTEQELIGL----LQAREKEVHDLEIQLTAITTSEQYYSKEVKD 501
Query: 778 PVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNN 833
+ K K EL + C K +E+ +L + + ++ K + ED NN
Sbjct: 502 LKTELENEKLKNTELTSHCN------KLSLENKELTQETSDMTLELKNQQ-EDINN 550
>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
Length = 1460
Score = 40.4 bits (93), Expect = 0.007
Identities = 64/330 (19%), Positives = 129/330 (39%), Gaps = 60/330 (18%)
Query: 501 VPTEENEMSSEADMECLNQRPPENPDTDKNVQQ-----DNSEAGTQPQVQTDAQQTSQSP 555
+P EE S + + PP+ P+ ++ ++S A Q+ +Q P
Sbjct: 475 LPHEERAQSPPRSL-ATEEEPPQGPEGQPEWKEAEELGEDSAASLSLQLSLQREQAPSPP 533
Query: 556 PSPELTSEENKIPD--------ADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLG 607
+ E E++ + A+ EK P P+++ P E QL
Sbjct: 534 AACEKGKEQHSQAEELGPGQEEAEDPEEKVAVSPTPPVSPEVRSTEPVAPPE-----QLS 588
Query: 608 KDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLR 667
+ L E ++ LE+++ + +E + + R+KL C+++ + LR
Sbjct: 589 EAALKAMEEAVAQV-----LEQDQRHLLESKQEKMQQLREKL--------CQEEEEEILR 635
Query: 668 LLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEA--EERPKMFEELGQRLQH 725
L Q K+ + L E R Q+A EE +M EE QRL
Sbjct: 636 L-------------HQQKEQSLSSLRE----------RLQKAIEEEEARMREEESQRLSW 672
Query: 726 Y-AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQ-DPVVRAQ 783
A++ + + +++ E+ ++K+ + + + + + ++ L+Q + A
Sbjct: 673 LRAQVQSSTQADEDQIRAEQEASLQKLREELESQQKAERASLEQKNRQMLEQLKEEIEAS 732
Query: 784 EIKTKIKELNNTCEPVVTQPKPKIESPKLE 813
E K++ LN E + Q + ++E + E
Sbjct: 733 E-KSEQAALNAAKEKALQQLREQLEGERKE 761
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 40.0 bits (92), Expect = 0.009
Identities = 46/212 (21%), Positives = 93/212 (43%), Gaps = 29/212 (13%)
Query: 559 ELTSEENKIPDADKANEKKVDQPPEAKK----PKIKVVNVELPIEANLVWQLGKD--LLN 612
+L E+ ++ + K EKK+D AK+ P IK E I+ +W+ ++ +
Sbjct: 676 QLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITT 735
Query: 613 MYIETEGKMIMQDKLEKERNDAK------NAVEEYVYEFRDKLCGPYEKFICEQDHQNFL 666
M +E E + ++++ + D A + VYE + K +E+ + E+ H
Sbjct: 736 MQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLK---QFEERLAEERHNRLE 792
Query: 667 RLLTETED-----WLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQ 721
+ ++ + E+ E++ ++A L+E + +E ER K EEL +
Sbjct: 793 ERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE---------RERAERAKREEELRE 843
Query: 722 RLQHYAKIAADFRNKDEKYNHIDESEMKKVEK 753
+ K+ R K ++ I+E E ++ E+
Sbjct: 844 YQERVKKLEEVERKKRQRELEIEERERRREEE 875
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 39.3 bits (90), Expect = 0.016
Identities = 54/262 (20%), Positives = 109/262 (41%), Gaps = 23/262 (8%)
Query: 507 EMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQ---PQVQTDAQ---QTSQSPPSPEL 560
E SE + L+ RPP ++ ++ + + Q P+ + Q Q + +
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 561 TSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGK 620
EE ++ ++A + + ++ ++ + + + E + WQL ++ K
Sbjct: 834 LEEEEQLQRRERAQQLQ-EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK 892
Query: 621 MIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEG 680
+Q++L KE+ + EE E R+K + E+ ++ +L E E L EE
Sbjct: 893 PALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ----ERQYREEEQLQQEEEQLLREER 948
Query: 681 EDQAKQ---------AYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAA 731
E + +Q + + EE + P K R QE E++ + EEL Q + +
Sbjct: 949 EKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREER 1008
Query: 732 DFRNKDE---KYNHIDESEMKK 750
+ R + E +Y DE + ++
Sbjct: 1009 EKRRRQEWERQYRKKDELQQEE 1030
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 39.3 bits (90), Expect = 0.016
Identities = 64/317 (20%), Positives = 124/317 (39%), Gaps = 50/317 (15%)
Query: 499 EKVPTEENEMSSEAD-----MECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQ 553
+K+ E++E+ E D +E L++ T + V+ SE + + QT
Sbjct: 1219 QKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLN 1278
Query: 554 SPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNM 613
+ L ++ ++ + E + Q ++K+ L QL + M
Sbjct: 1279 MQKA-RLQTQNGELSHRVEEKESLISQLTKSKQA--------------LTQQLEELKRQM 1323
Query: 614 YIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETE 673
ET+ K M L+ R+D E+Y E K + + + +E
Sbjct: 1324 EEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAK----------AELQRALSKANSEVA 1373
Query: 674 DWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPK-------MFEELGQRLQHY 726
W + D + + EEL + + R QEAEE + E+ QRLQ
Sbjct: 1374 QWRTKYETDA-----IQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQG- 1427
Query: 727 AKIAADFRNKDEKYNHIDESEMKKVEKSVNEVM-EWMNNVMNAQAKKSLDQDPVVRAQEI 785
+ +D + +H + + K +++ ++V+ EW + +QA+ Q ++ +
Sbjct: 1428 ---EVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQK---ESRSL 1481
Query: 786 KTKIKELNNTCEPVVTQ 802
T++ ++ N E VV Q
Sbjct: 1482 STELFKMRNAYEEVVDQ 1498
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 38.9 bits (89), Expect = 0.021
Identities = 61/316 (19%), Positives = 124/316 (39%), Gaps = 49/316 (15%)
Query: 492 ISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQT 551
+ + S + EENE+ LNQ+ E + Q+ E + +++ Q+
Sbjct: 271 LQSVSAKLQAQVEENEL-----WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325
Query: 552 SQSPPSPELTSEENKIPDAD----------KANEKKVDQPPEA---KKPKIKVVNVELPI 598
++ +E KI + + + E+K+ + E ++ KI+ + ++
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 599 EANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFIC 658
+ +W+ + + + + KM Q+K +E+++ EE ++ +K+ E
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM-- 443
Query: 659 EQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEE 718
QD + LR E E+ + EE E + QE EE+ + EE
Sbjct: 444 -QDQEEKLR---EVEEKMQEEEE-----------------------KMQEQEEKIQRQEE 476
Query: 719 LGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEK--SVNEVMEWMNNVMNAQAKKSLDQ 776
Q + ++EK +E ++ EK E M+ M Q +K +Q
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 777 DPVVRAQEIKTKIKEL 792
+ + QE K + +E+
Sbjct: 537 EVRLWQQEEKMQEQEV 552
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 38.9 bits (89), Expect = 0.021
Identities = 61/316 (19%), Positives = 124/316 (39%), Gaps = 49/316 (15%)
Query: 492 ISTASMVEKVPTEENEMSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQT 551
+ + S + EENE+ LNQ+ E + Q+ E + +++ Q+
Sbjct: 271 LQSVSAKLQAQVEENEL-----WNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEE 325
Query: 552 SQSPPSPELTSEENKIPDAD----------KANEKKVDQPPEA---KKPKIKVVNVELPI 598
++ +E KI + + + E+K+ + E ++ KI+ + ++
Sbjct: 326 KMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQE 385
Query: 599 EANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFIC 658
+ +W+ + + + + KM Q+K +E+++ EE ++ +K+ E
Sbjct: 386 QEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM-- 443
Query: 659 EQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEE 718
QD + LR E E+ + EE E + QE EE+ + EE
Sbjct: 444 -QDQEEKLR---EVEEKMQEEEE-----------------------KMQEQEEKIQRQEE 476
Query: 719 LGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEK--SVNEVMEWMNNVMNAQAKKSLDQ 776
Q + ++EK +E ++ EK E M+ M Q +K +Q
Sbjct: 477 KIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Query: 777 DPVVRAQEIKTKIKEL 792
+ + QE K + +E+
Sbjct: 537 EVRLWQQEEKMQEQEV 552
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.021
Identities = 66/367 (17%), Positives = 139/367 (37%), Gaps = 31/367 (8%)
Query: 490 FTISTASMVEKVPTEENE-MSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDA 548
+ + +E +P EE + + E M +N++ +P + K Q+ +P+ A
Sbjct: 317 YEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSA 376
Query: 549 QQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGK 608
+L E ++ +++ ++K K K E ++A + G
Sbjct: 377 MFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 436
Query: 609 DLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRL 668
+ E GK+ K +E ++ + +Y+ F++ + E N +
Sbjct: 437 ER-----EERGKLPESPKRAEEIWQ-QSVIGDYLARFKNDRVKALKAM--EMTWNNMEK- 487
Query: 669 LTETEDWLYEEGEDQAKQAYVDKLEELMK----IGTPVKVRFQEAEERPKM--FEELGQR 722
E W+ + EDQ + Y +L E+ + K++FQ ++P M +++ Q
Sbjct: 488 -KEKLMWIKKAAEDQKR--YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQE 544
Query: 723 LQ-----HYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQD 777
L ++ + ++ I +S+ + +K E + ++ K QD
Sbjct: 545 LLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQD 604
Query: 778 PVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAE 837
+ I K K + + P PK L+ D+++ED ED++ E
Sbjct: 605 RAAYKEYISNKRKSMTK-----LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDE--EE 657
Query: 838 PPHQNGE 844
+NG+
Sbjct: 658 EDDENGD 664
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 38.9 bits (89), Expect = 0.021
Identities = 66/367 (17%), Positives = 139/367 (37%), Gaps = 31/367 (8%)
Query: 490 FTISTASMVEKVPTEENE-MSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDA 548
+ + +E +P EE + + E M +N++ +P + K Q+ +P+ A
Sbjct: 317 YEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSA 376
Query: 549 QQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGK 608
+L E ++ +++ ++K K K E ++A + G
Sbjct: 377 MFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 436
Query: 609 DLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRL 668
+ E GK+ K +E ++ + +Y+ F++ + E N +
Sbjct: 437 ER-----EERGKLPESPKRAEEIWQ-QSVIGDYLARFKNDRVKALKAM--EMTWNNMEK- 487
Query: 669 LTETEDWLYEEGEDQAKQAYVDKLEELMK----IGTPVKVRFQEAEERPKM--FEELGQR 722
E W+ + EDQ + Y +L E+ + K++FQ ++P M +++ Q
Sbjct: 488 -KEKLMWIKKAAEDQKR--YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQE 544
Query: 723 LQ-----HYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQD 777
L ++ + ++ I +S+ + +K E + ++ K QD
Sbjct: 545 LLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQD 604
Query: 778 PVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAE 837
+ I K K + + P PK L+ D+++ED ED++ E
Sbjct: 605 RAAYKEYISNKRKSMTK-----LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDE--EE 657
Query: 838 PPHQNGE 844
+NG+
Sbjct: 658 EDDENGD 664
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 38.9 bits (89), Expect = 0.021
Identities = 66/367 (17%), Positives = 139/367 (37%), Gaps = 31/367 (8%)
Query: 490 FTISTASMVEKVPTEENE-MSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDA 548
+ + +E +P EE + + E M +N++ +P + K Q+ +P+ A
Sbjct: 354 YEVELLRFLESLPEEEQQRVLGEEKMLNINKKQATSPASKKPAQEGGKGGSEKPKRPVSA 413
Query: 549 QQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGK 608
+L E ++ +++ ++K K K E ++A + G
Sbjct: 414 MFIFSEEKRRQLQEERPELSESELTRLLARMWNDLSEKKKAKYKAREAALKAQSERKPGG 473
Query: 609 DLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRL 668
+ E GK+ K +E ++ + +Y+ F++ + E N +
Sbjct: 474 ER-----EERGKLPESPKRAEEIWQ-QSVIGDYLARFKNDRVKALKAM--EMTWNNMEK- 524
Query: 669 LTETEDWLYEEGEDQAKQAYVDKLEELMK----IGTPVKVRFQEAEERPKM--FEELGQR 722
E W+ + EDQ + Y +L E+ + K++FQ ++P M +++ Q
Sbjct: 525 -KEKLMWIKKAAEDQKR--YERELSEMRAPPAATNSSKKMKFQGEPKKPPMNGYQKFSQE 581
Query: 723 LQ-----HYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQD 777
L ++ + ++ I +S+ + +K E + ++ K QD
Sbjct: 582 LLSNGELNHLPLKERMVEIGSRWQRISQSQKEHYKKLAEEQQKQYKVHLDLWVKSLSPQD 641
Query: 778 PVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAE 837
+ I K K + + P PK L+ D+++ED ED++ E
Sbjct: 642 RAAYKEYISNKRKSMTK-----LRGPNPKSSRTTLQSKSESEEDDEEDEDDEDEDE--EE 694
Query: 838 PPHQNGE 844
+NG+
Sbjct: 695 EDDENGD 701
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.373
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,507,802
Number of Sequences: 37866
Number of extensions: 1507058
Number of successful extensions: 5446
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 29
Number of HSP's successfully gapped in prelim test: 270
Number of HSP's that attempted gapping in prelim test: 4912
Number of HSP's gapped (non-prelim): 743
length of query: 858
length of database: 18,247,518
effective HSP length: 111
effective length of query: 747
effective length of database: 14,044,392
effective search space: 10491160824
effective search space used: 10491160824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.