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Search of human proteins with 42542379
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
(904 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 1807 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 213 8e-55
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 157 3e-38
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 146 7e-35
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 146 7e-35
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 138 2e-32
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 138 2e-32
gi|158854042 hypothetical protein LOC222183 [Homo sapiens] 134 5e-31
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 134 5e-31
gi|163965366 nascent polypeptide-associated complex alpha subuni... 128 3e-29
gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 125 1e-28
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 125 2e-28
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 124 5e-28
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 118 3e-26
gi|50083281 KIAA1853 protein [Homo sapiens] 117 6e-26
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens] 112 1e-24
gi|150170670 piccolo isoform 2 [Homo sapiens] 112 2e-24
gi|150378539 piccolo isoform 1 [Homo sapiens] 112 2e-24
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 111 3e-24
gi|153251865 hypothetical protein LOC84226 [Homo sapiens] 110 5e-24
gi|116284392 mucin 2 precursor [Homo sapiens] 109 1e-23
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 109 1e-23
gi|18079216 CASK interacting protein 1 [Homo sapiens] 107 4e-23
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 107 4e-23
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 107 4e-23
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 106 9e-23
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 105 2e-22
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 105 2e-22
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 104 4e-22
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 103 7e-22
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 1807 bits (4681), Expect = 0.0
Identities = 904/904 (100%), Positives = 904/904 (100%)
Query: 1 MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEIL 60
MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEIL
Sbjct: 1 MDAGFFRGTSAEQDNRFSNKQKKLLKQLKFAECLEKKVDMSKVNLEVIKPWITKRVTEIL 60
Query: 61 GFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIP 120
GFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIP
Sbjct: 61 GFEDDVVIEFIFNQLEVKNPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIP 120
Query: 121 SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP 180
SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP
Sbjct: 121 SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP 180
Query: 181 SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS 240
SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS
Sbjct: 181 SPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATS 240
Query: 241 TSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
TSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR
Sbjct: 241 TSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
Query: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
Query: 361 SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS
Sbjct: 361 SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
Query: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ
Sbjct: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
Query: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET 540
QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET
Sbjct: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET 540
Query: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI 600
SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI
Sbjct: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI 600
Query: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH
Sbjct: 601 QRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
Query: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP
Sbjct: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720
Query: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW 780
IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW 780
Query: 781 SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA 840
SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA
Sbjct: 781 SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA 840
Query: 841 AAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQV 900
AAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQV
Sbjct: 841 AAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQV 900
Query: 901 SPQS 904
SPQS
Sbjct: 901 SPQS 904
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 213 bits (541), Expect = 8e-55
Identities = 245/825 (29%), Positives = 340/825 (41%), Gaps = 119/825 (14%)
Query: 140 KLASMKKQDEDKDKRDKEEKESSREKRERSRSPR---------RRKSRSPSPRRRSSPVR 190
K S +D+DKDK++K S S P R SP P ++P+
Sbjct: 329 KQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLA-TTPLS 387
Query: 191 RERKRSHSRSPRHRTKSRSPSPAPEK------KEKTPELPEPSVKVKEPSVQEATSTSDI 244
+E S + T+ RSP +PEK E +P P+P+ V S+S
Sbjct: 388 QEPVNPPSEASP--TRDRSPPKSPEKLPQSSSSESSPPSPQPT------KVSRHASSSP- 438
Query: 245 LKVPKPEPIP-EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
+ PKP P P +E S SK R +S S + SR RSRSP+ T R R R
Sbjct: 439 -ESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPA-TAKRGRSR 496
Query: 304 SRS---RSYSPRRRPSPRRRPSPRR----RTPPRR----MPPPPRHRRSRSPVRRRRRSS 352
SR+ R +S R P RR S +R R+P RR P P RSR+ RR R S
Sbjct: 497 SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRS 556
Query: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK-TRRLSPSASPPRRRHRPSPPA------ 405
A S S S ++R RS + P +R S R RR S S +P RRR R PA
Sbjct: 557 ARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR 616
Query: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES 465
+ P R S T R +SR SP R SG+ + S S P R S +
Sbjct: 617 SRTPARRRSRTRSPVRRRSRSR---SPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRT 673
Query: 466 EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP 525
+ G+ + ++ R R ++ S S RS V+ G R
Sbjct: 674 PARRSGRSRSRTPARRGRSRSRTPRRGRSRS------------RSLVRRGRSHSRTPQRR 721
Query: 526 SRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP 585
RS S S RK + TS R R RS S P ++ R S RR PR + S
Sbjct: 722 GRSGSSSERKNKSRTSQR--RSRSNSSPEMKKSRISS------RRSRSLSSPRSKAKSRL 773
Query: 586 PRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS 645
RRS S S P ++ S +PP + R+ S P K R +PP + R S SPPPKQ+S
Sbjct: 774 SLRRSLSG---SSPCPKQKSQTPPRRSRSGSSQPKAKSR---TPPRRSRSSSSPPPKQKS 827
Query: 646 SPVTKRRSPSLSSKHRK---GSSPSRSTREARSPQPNKRH-----------SPSP--RPR 689
R+S S SS H K G+ P + + SPQ N++ SP P + R
Sbjct: 828 K-TPSRQSHSSSSPHPKVKSGTPPRQGS--ITSPQANEQSVTPQRRSCFESSPDPELKSR 884
Query: 690 APQ----TSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745
P + SSPP V+ SS RQSPS S+ P +V P++ + S SP R
Sbjct: 885 TPSRHSCSGSSPPRVK----SSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR 940
Query: 746 ---RVSSSRSVSGSPEPAAKKPPAPP-SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
R + RS S SP + P S S SP T P P +++ S + SP P
Sbjct: 941 VTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVK 1000
Query: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEE 861
+ G K +K K+ V + + A + ++T
Sbjct: 1001 AQTPPGPSLSGSKSPCPQEK----------SKDSLVQSCPGSLSLCAGVKSSTPPGESYF 1050
Query: 862 PVAAPEPKKETESEAEDNLDDLEKHLREKALRS---MRKAQVSPQ 903
V++ + K ++++ + D +R+ S K+Q SP+
Sbjct: 1051 GVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPK 1095
Score = 207 bits (527), Expect = 4e-53
Identities = 238/816 (29%), Positives = 345/816 (42%), Gaps = 151/816 (18%)
Query: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP-----------R 202
R + E +SS E + ++PR R SP + + +R+RS S S
Sbjct: 1475 RGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLG 1534
Query: 203 HRTKSRS-------PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255
R++S S PS +P+++ ++ P+ K + P Q + S S PE +
Sbjct: 1535 QRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSS------PE-VDS 1587
Query: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR-HRSRSRSYSPRRR 314
SP ++ + K +PR+ R++S S + S P PR RSRS S S R
Sbjct: 1588 KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDS-SPEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
PSP S + P PP+ R +R R SS ++SR+PP++
Sbjct: 1647 PSPEGSSSTE--SSPEH---PPKSRTARRGSR------------SSPEPKTKSRTPPRRR 1689
Query: 375 PKRTSSPPRKTRRLS-----PSASPPRR-----RHRPSPPATPPPKTRHSPTPQQSNRTR 424
R+S + RLS S+SP R RHR SP + SP P + +R+
Sbjct: 1690 SSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVS-------SPEPAEKSRSS 1742
Query: 425 KSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ 484
+ R S S RT T R SP+PKPR ++ S S + RR+
Sbjct: 1743 RRRRSASSPRTK--------TTSRRGRSPSPKPRGLQRSRS--------------RSRRE 1780
Query: 485 YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544
R ++ D SS S R +RS ++ RRR S S SP+ R+ TS R
Sbjct: 1781 KTRTTRR--RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPA-RQESSRTSSRR 1837
Query: 545 RRRRSPSPPPTRR--RRSPSPAPPPRRRRTPTPPPRR----RTP-----------SPPPR 587
RR RS +PP +R+ R SPAP R R +P R RTP SP R
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR 1897
Query: 588 RRSPS--------PRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRA-SPSPPPKRRV 635
RRS S R + P+ RR S S P +RR+ S P +RR+ S +PP RR
Sbjct: 1898 RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRR 1957
Query: 636 SHSPPP-------KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP 688
S S P + R+SP+T+RRS S +S + S SR++ R R SP
Sbjct: 1958 SRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR---RSRSRTSPVT 2014
Query: 689 RAPQTSSSPPPVRRGASSSP---QRRQSPSPSTRPIRR--VSRTPEPKKIKKAASPSPQS 743
R S +PP +RR + S R++S S S IRR SRTP + K++ + SP +
Sbjct: 2015 RRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPA 2074
Query: 744 VRRVSSSRSVSGSPEPAAKKPPA---------PPSPVQSQSPSTNWSPAV---PVKKAKS 791
+RR S+S S S A PPA PP + S S P++ P+ + +S
Sbjct: 2075 IRRRSASGSSSDRSRSAT--PPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRS 2132
Query: 792 -----PTPSPSPPRNSDQEGGGKKKKKKKDK--KHKKDKKHKKHKKHKKEKAVAAAAAAA 844
P S P + Q+ GG + H++ + H + + A+ A +
Sbjct: 2133 PGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGT 2192
Query: 845 VTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNL 880
P +A A+ V AP P + NL
Sbjct: 2193 ARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANL 2228
Score = 197 bits (500), Expect = 5e-50
Identities = 243/883 (27%), Positives = 344/883 (38%), Gaps = 206/883 (23%)
Query: 107 PLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK- 165
P L + + + P+ + KK++ + + + +++ K K+ + E ES + K
Sbjct: 170 PYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKH 229
Query: 166 -------RERSRSPRRRKSRSPSPRRRSSPVRR----------ERKRSHSRSPRHRTKS- 207
+ +S+ +R++SRS +P +S R + RS SRS +T +
Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289
Query: 208 ----RSPSPA----------------------------------------PEKKEKTPEL 223
RSPSPA +KKEK+
Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 224 PEPSVK-----------------------------------VKEPSVQEATSTSDILKVP 248
P PS + V PS EA+ T D
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPS--EASPTRDRSPPK 407
Query: 249 KPEPIPE-------PKEPSPEK-----NSKKEKEKEKTRPRSR--------SRSKSRSRT 288
PE +P+ P P P K +S E K P S S+++S R
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRA 467
Query: 289 -RSRSPSHTRPRRRHRSRS----------------RSYSPRRRPSPRRRPSPRR----RT 327
R +S SHT RR RSRS R +S R P RR S +R R+
Sbjct: 468 KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRS 527
Query: 328 PPR----RMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR 383
P R R P P RSR+ RR R SA S S S ++R RS + P +R S R
Sbjct: 528 PQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSR 587
Query: 384 -KTRRLSPSASPPRRRHRPSPPA------TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436
RR S S +P RRR R PA + P R S T R +SR SP R S
Sbjct: 588 TPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSR---SPARRS 644
Query: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
G+ + S S P R S + + G+ + ++ R R ++ S S
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
Query: 497 GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTR 556
RS V+ G R RS S S RK + TS RR RS S P +
Sbjct: 705 ------------RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQ--RRSRSNSSPEMK 750
Query: 557 R-----RRSPSPAPPPRRRRT----------PTPPPRRRTPSPPPRRRS----PSPRRYS 597
+ RRS S + P + ++ +P P++++ +PP R RS P + +
Sbjct: 751 KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRT 810
Query: 598 PPIQRRYSPSPPPKRRTASPPPPPKRRASPSP-----PPKRRVSHSPPPKQRSSPVTKRR 652
PP + R S SPPPK+++ +P +SP P P R+ S + P S +RR
Sbjct: 811 PPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRR 870
Query: 653 S--PSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQR 710
S S K +PSR + SP P + S PR ++P SSSP P + S QR
Sbjct: 871 SCFESSPDPELKSRTPSRHSCSGSSP-PRVKSSTPPR-QSPSRSSSPQPKVKAIISPRQR 928
Query: 711 RQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770
S S S P R SRT P++ ++ SP R+ S SGS P K P P P
Sbjct: 929 SHSGSSSPSPSRVTSRT-TPRR-SRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP-P 985
Query: 771 VQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK 813
QS S S + P K K+ TP P P + + ++K K
Sbjct: 986 RQSHSGSIS-----PYPKVKAQTP-PGPSLSGSKSPCPQEKSK 1022
Score = 190 bits (483), Expect = 4e-48
Identities = 217/842 (25%), Positives = 329/842 (39%), Gaps = 123/842 (14%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQ--DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP 182
E+ +E+ + Q QEK+A+ + ++D + KEE R + +
Sbjct: 75 EMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNER 134
Query: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTS 242
R + + S P+ R + E K+ PE P+P V+E S + +
Sbjct: 135 LRAAFGISDSYVDGSSFDPQRRAR--------EAKQPAPEPPKPYSLVRESSSSRSPTPK 186
Query: 243 DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH 302
K K + + SP + KK +K+K R S S+ + +S ++ ++R
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246
Query: 303 RSRSRSYSPRRRPSPRRRPS----------PRRRTPPRRMPPPPRHRRSRSPVRRRRRSS 352
RSRS + +P+ R + R + R R+ + RS SP RR
Sbjct: 247 RSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEG 306
Query: 353 ASLSGSSSSSSSSRSRSP------PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA- 405
+ ++S+ R SP P P + ++ PS SP R P PPA
Sbjct: 307 DAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Query: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG---------------------------- 437
TP RH +PQ T S+ V+P +
Sbjct: 367 TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQ 426
Query: 438 --KVTKHKGTEKRESPSPAPKP---RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492
KV++H + ESP PAP P R++ S + +++ A D RR +
Sbjct: 427 PTKVSRH-ASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 493 SSDSGSSSSSEDERP-KRSHVKNGEVGRRRRHSPSR-SASPSPRKRQKETSP-------- 542
S + S P KR H ++ RR S R S SP++R + SP
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
Query: 543 -----RGRRR----------------RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
RGR R RS S P RR RS S P RR R+ T P RRR+
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRT-PTRRRS 604
Query: 582 PSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR-VSHSPP 640
S P RR S R P +RR P +RR+ S P + S S P RR S S
Sbjct: 605 RSRTPARRGRS--RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT 662
Query: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
P +R ++ R+P+ S + +P+R R +RS P + S S S S P
Sbjct: 663 PARRGR--SRSRTPARRSGRSRSRTPARRGR-SRSRTPRRGRSRSRSLVRRGRSHSRTPQ 719
Query: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKK-------IKKAASPSPQSVRRVSSSRSV 753
RRG S S R++ S +++ R + +PE KK + +SP ++ R+S RS+
Sbjct: 720 RRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSL 779
Query: 754 SGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK 813
SGS +K PP +S S KAKS T PPR S K+K
Sbjct: 780 SGSSPCPKQKSQTPPRRSRSGSSQ---------PKAKSRT----PPRRSRSSSSPPPKQK 826
Query: 814 KKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT-PAAIAAATTTLAQEEPVAAPEPKKET 872
K + H H K K+ ++T P A + T + ++P+P+ ++
Sbjct: 827 SKTPSR---QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS 883
Query: 873 ES 874
+
Sbjct: 884 RT 885
Score = 189 bits (480), Expect = 1e-47
Identities = 233/816 (28%), Positives = 331/816 (40%), Gaps = 155/816 (18%)
Query: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS--------PV 189
++K + + D + + + R RSRS K R PSP SS P
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664
Query: 190 RRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPK 249
R +R SP +TKSR+P P +PEL + + + A+S+ +
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTP-PRRRSSRSSPELTRKARLSRRS--RSASSSPETRSRTP 1721
Query: 250 PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY 309
P P SPE ++K + + R S R+K+ SR R RSPS +PR RSRSRS
Sbjct: 1722 PRHRRSPSVSSPEP-AEKSRSSRRRRSASSPRTKTTSR-RGRSPS-PKPRGLQRSRSRSR 1778
Query: 310 SPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS 369
+ R + RR S ++ RR + RSRS V RRRR S SRS
Sbjct: 1779 REKTRTTRRRDRSGSSQSTSRRR----QRSRSRSRVTRRRR----------GGSGYHSRS 1824
Query: 370 PPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
P ++ RTSS R+ R +P S R R R SP ++R SP + +R+R +S
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLIS 1884
Query: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
+ + R SP + R + SV +RR R +
Sbjct: 1885 ------------RRRSRSRTSPVSRRRSR----------------SRTSVTRRRSRSRAS 1916
Query: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
S +RS + V RRR SRS +P+ R+R + +P RRRS
Sbjct: 1917 PVSR--------------RRSRSRTPPVTRRR----SRSRTPTTRRRSRSRTPPVTRRRS 1958
Query: 550 PS-PPPTRRRRSPSPAPPPRRRRT---PTPPPRRRT---PSPPPRRRSPSPRRYSPPIQR 602
S PP RRRS S P RRR+ +P RRR+ SP RRRS S R SP +R
Sbjct: 1959 RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRS--RTSPVTRR 2016
Query: 603 RYSPSPPP--KRRTASPPP--PPKRRASPSPPPKRRVSHSPPPK--------QRSSPVTK 650
R PP +RR+ S P P KR S SP RR S S P+ RS P +
Sbjct: 2017 RSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIR 2076
Query: 651 RRSPSLSSKHRKGSSPSRSTRE---ARSP-------------QPNKRHSPSPRPRAP--- 691
RRS S SS R S+ +TR +R+P +P+ +P R R+P
Sbjct: 2077 RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136
Query: 692 ---QTSSSPPPVRRGASSS---------PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
+S +P V + A S P +++ P R++ + A P
Sbjct: 2137 EPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPP 2196
Query: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTN---------WSPAVP--VKK 788
S +++ S +P P AP + + S+ P+ + +PA+P V
Sbjct: 2197 PSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNL 2256
Query: 789 AKSPTPSPSPPRN--SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT 846
A S TP+ + N S + D + A A A A T
Sbjct: 2257 ADSRTPAAAAAMNLASPRTAVAPSAVNLADP--------------RTPTAPAVNLAGART 2302
Query: 847 PAAIAAATTTLAQEEPVAA--PEPKKETESEAEDNL 880
PAA+AA + T + P AA P + ++ A NL
Sbjct: 2303 PAALAALSLTGSGTPPTAANYPSSSRTPQAPASANL 2338
Score = 150 bits (380), Expect = 4e-36
Identities = 204/776 (26%), Positives = 303/776 (39%), Gaps = 139/776 (17%)
Query: 159 KESSREKRERSRSPRRRK-SRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKK 217
+ S ++R RSRSP+R SRS + +RR R RSHSRSP R +SRS +PA +
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
++ + + P+ + + S + P + +P + + + + R R
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRT-------PARRGRSRSRTPARRRSRTRSPVRRRSR 636
Query: 278 SRSRSKSRSRTRSRSPSHT-RPRRR---HRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMP 333
SRS ++ R+RSR+P+ R R R R RSRS +P RR R +P RR R
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 334 PPPRHRRSRSPVRRRRRSSASLS--GSSSSSSSSRSRSPPKKPPKRTSSPP-----RKTR 386
P RSRS VRR R S + G S SSS +++S + R++S P R +
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISS 756
Query: 387 RLSPSASPPRRRHR-------------PSPPA---TPPPKTRH-SPTPQQSNRT--RKSR 427
R S S S PR + + P P TPP ++R S P+ +RT R+SR
Sbjct: 757 RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816
Query: 428 VSVSPGRTSGKVTKHKGTEKRESPSPAPK------------PRKVELSESEEDKGGKMAA 475
S SP T + + SP P K P+ E S + + + ++
Sbjct: 817 SSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESS 876
Query: 476 AD-SVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR---RRRHSPSRSASP 531
D ++ R R SS SS+ + P RS +V R+ S S S+SP
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
Query: 532 SPRKRQKETSPRGRRRRSP------------------SPP-------PTRRRRSPSPAPP 566
SP + T+PR R SP SP P R+ S S +P
Sbjct: 937 SPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY 996
Query: 567 PR-RRRTPTPPPRRRTPSPPPRRRSPSP---------------RRYSPP----------- 599
P+ + +TP P + SP P+ +S + +PP
Sbjct: 997 PKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQ 1056
Query: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
++ + SP + T+SP SPS K + S + SSPVT+ S S +
Sbjct: 1057 LKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQ 1116
Query: 660 HRKGSSPSRSTREARSPQPNKRHSPSPR------------------------PRAPQTSS 695
R S S + SP+ ++ S S PQ +
Sbjct: 1117 DRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
Query: 696 SPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS--------PQSVRRV 747
+ P R+ SP Q S+ + RTP ++ +SP P S +
Sbjct: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDE 1236
Query: 748 SSSRSVSGSPEPAAKKPPAPPSPVQSQSPST-NWSPAVPVKKAKSPTPSPSPPRNS 802
V S EPA + S ++ S S SP V + A S T S + S
Sbjct: 1237 ELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQAS 1292
Score = 139 bits (349), Expect = 2e-32
Identities = 209/827 (25%), Positives = 311/827 (37%), Gaps = 137/827 (16%)
Query: 153 KRDKEEKESSREKRERSRSP--RRRKSRSPSPRRRSSPVRRERKRSHSRS--PRHRTKSR 208
KR + + +R RSR+P RR+SRS R+SPV R+RS SR+ R R++SR
Sbjct: 1862 KRSRSRASPATHRRSRSRTPLISRRRSRS-----RTSPV--SRRRSRSRTSVTRRRSRSR 1914
Query: 209 -SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK 267
SP + +TP + + + P+ + + + + P+ + S +
Sbjct: 1915 ASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS-------RTPPVTRRRSRSRTPPVTR 1967
Query: 268 EKEKEKTRPRSRSRSKSRSR--TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR 325
+ + +T P +R RS+SR+ TR RS S T P R RSRSR+ RR S R P R
Sbjct: 1968 RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIR 2027
Query: 326 RTPPRRMPPPPRHR-RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
R R P PR R RSRSP+ RRR S S + ++ S +RSPP +R++S
Sbjct: 2028 RRSRSRTPLLPRKRSRSRSPLAIRRR-SRSRTPRTARGKRSLTRSPP-AIRRRSASGSSS 2085
Query: 385 TRRLSPSASPPRRRHRPSPPATPP-----------PKTRHSPTPQQSNRTRKSRVSVSPG 433
R S SA+PP R+ S TPP + SPTP R+ +
Sbjct: 2086 DR--SRSATPPATRNH-SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSS 2142
Query: 434 RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS 493
RT V + G + P P P S E ++A A + R S+
Sbjct: 2143 RTPMSVLQQAGGSMMDGPGPR-IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSA 2201
Query: 494 SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS----PSPRKRQKETSPRGRRRRS 549
+ + S ++ P+ SA+ S R T+ R+
Sbjct: 2202 AGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRT 2261
Query: 550 PSPPPTRRRRSPSPAPPPRR-----RRTPTPP----PRRRTP------------SPPPRR 588
P+ SP A P RTPT P RTP +PP
Sbjct: 2262 PAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAA 2321
Query: 589 RSPSPRR----------YSPPIQRRYSPSPPPKRRTASPPPPP----------------- 621
PS R P +P RTA+ P
Sbjct: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLT 2381
Query: 622 ---------KRRASPSPPP--KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRS- 669
+R + + PP R S +PP S +T R+PS SS R G +PS+S
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSS--RMGQAPSQSL 2439
Query: 670 ----TREARSPQPNKRHSPS------PRPRAPQTSSSPPPVRRGASSSPQRR---QSPSP 716
+ RSP P+ S P A S S V SS+ P+P
Sbjct: 2440 LPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAP 2499
Query: 717 STRPIRRVSRTPEPKKIKKAASPS------PQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770
S EP A PS P RR SSS S S S ++ + S
Sbjct: 2500 GVPH----SDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS 2555
Query: 771 VQSQSPSTNWS-----PAVPVKKAKSPTPSPSPP----RNSDQEGGGKKKKKKKDKKHKK 821
S S + S P V +K+ SPTP+P R + +K++
Sbjct: 2556 SGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSS 2615
Query: 822 DKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEP 868
+ +++++++ + ++ ++++ + A+ P A P+P
Sbjct: 2616 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKP 2662
Score = 137 bits (344), Expect = 6e-32
Identities = 183/711 (25%), Positives = 263/711 (36%), Gaps = 71/711 (9%)
Query: 132 KQRQIEQEKLASMKKQDEDKDKRDKE---EKESSREKRERSRSPRRRKSRSPSPRRRSSP 188
K R +++ + S +++ +RD+ + S R +R RSRS R+ R S SP
Sbjct: 1766 KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSP 1825
Query: 189 VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVP 248
R+E R+ SR R R +SR+P P K+ ++ P P K AT + P
Sbjct: 1826 ARQESSRTSSR--RRRGRSRTP-PTSRKRSRSRTSPAPW-KRSRSRASPATHRRSRSRTP 1881
Query: 249 KPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS 308
SP + TR RSRSR+ SR RSRS T P R RSRSR+
Sbjct: 1882 LISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS--RTPPVTRRRSRSRT 1939
Query: 309 YSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR-SPVRRRRRSSASLSGSSSSSSSSRS 367
+ RRR R P RRR+ R P R RSR SP+ RRR S + S + SRS
Sbjct: 1940 PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRT---SPVTRRRSRS 1996
Query: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPP--RRRHRPSPPATPPPKTRHSPTPQQSNRTRK 425
R+ P + S TRR S S +PP RRR R P P ++R S +P R +
Sbjct: 1997 RTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSR-SRSPLAIRRRSR 2055
Query: 426 SRVSVSPGRTSGK--VTKHKGTEKRESP--SPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
SR +P GK +T+ +R S S + + R + G +
Sbjct: 2056 SR---TPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSS 2112
Query: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
R + S + S P S V ++ S P Q+ +
Sbjct: 2113 RMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSV 2172
Query: 542 PRGRRRR------------SPSPPPT--------RRRRSPSPAPPPRRRRTPTPPPRRRT 581
P + + PPP+ R + P+P P R P R
Sbjct: 2173 PENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRI 2232
Query: 582 PSPPPRRRS-PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPS-----------P 629
P+ + S R + P + S P A P+ +PS
Sbjct: 2233 PAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA 2292
Query: 630 PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP--- 686
P P + +T +P ++ + S ++ A P H+ +P
Sbjct: 2293 PAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNI 2352
Query: 687 ---RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS---PS 740
R A +S R + S SP RVS P + +A S PS
Sbjct: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
S R++S R +P P+++ AP QS P P PV A S
Sbjct: 2413 APSQSRMTSER----APSPSSRMGQAPS---QSLLPPAQDQPRSPVPSAFS 2456
Score = 108 bits (269), Expect = 3e-23
Identities = 196/835 (23%), Positives = 316/835 (37%), Gaps = 133/835 (15%)
Query: 153 KRDKEEKESSREKRERSRS-PRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP- 210
+R S R SR+ PRR +S SP S + R S S SP + K +P
Sbjct: 927 QRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRY-SHSGSSSPDTKVKPETPP 985
Query: 211 --------SPAPEKKEKTPELPEPSVK-VKEPSVQEATSTSDILKVPKPEPI-------P 254
SP P+ K +TP P PS+ K P QE + S + P +
Sbjct: 986 RQSHSGSISPYPKVKAQTP--PGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSST 1043
Query: 255 EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS----RSRSYS 310
P E +S + K + +T P RS + S +S S S + + S RSRS S
Sbjct: 1044 PPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSS 1103
Query: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS------- 363
P + R SP R+ P + SP + R +S +S + S+S
Sbjct: 1104 PVTELASR---SPIRQDRGE-FSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRL 1159
Query: 364 -SSRSRSPPKKPPKR--TSSPPRKTRRLSPSA----------------SPPRRRHRPSPP 404
++ S+ PP+ T+SPPR+ + SP +PPR R
Sbjct: 1160 ETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG-- 1217
Query: 405 ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE--------SPSPAPK 456
++P K ++S P S V +G++ H +E +E SP +
Sbjct: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEER 1277
Query: 457 P---------------RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS 501
P VE+ GG + + + R+N S +S
Sbjct: 1278 PAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSG 1337
Query: 502 ---SEDERPKRSHVK---NGEVGRRRRHSPS----RSASPSPRKRQKETSPRGRRR---- 547
+E S VK NG + PS ++ S E SP +
Sbjct: 1338 PLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMS 1397
Query: 548 --RSPSPP--------PTRRRRSPSPAP---------PPRRRRTPTPPPRRRTPSPPPRR 588
+S S P P+R R S + +P P RR R+ + P R P R
Sbjct: 1398 SNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRH 1457
Query: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648
S SP + + P P + R+ P + +P P+ R SP +
Sbjct: 1458 ---SLSGSSPGM--KDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTP 1512
Query: 649 TKRRSPSLSSKHRK--GSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS 705
+ RS S SS +K +P + +R S + + + S SP+ R+ SS P + +
Sbjct: 1513 QRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSS---PDSKAKT 1569
Query: 706 SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSG---SPEPAAK 762
+P R++S S S+ + SR P++ + +SP + R ++ R+ SG SPEP A
Sbjct: 1570 RTPLRQRSRSGSSPEVDSKSRL-SPRRSRSGSSPEVKDKPR-AAPRAQSGSDSSPEPKAP 1627
Query: 763 KPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822
P A P +S S S P+ P + + + PP++ G + + K K
Sbjct: 1628 APRALPRRSRSGSSSKGRGPS-PEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP 1686
Query: 823 KKHKKHKK---HKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETES 874
++ +K + + +A+ +P + + V++PEP +++ S
Sbjct: 1687 RRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
Score = 102 bits (253), Expect = 2e-21
Identities = 116/393 (29%), Positives = 153/393 (38%), Gaps = 61/393 (15%)
Query: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR-HSPTPQQ-SNR 422
+RSR+PP P S R T +PS S R PS PP + + SP P S++
Sbjct: 2405 ARSRTPPSAP-----SQSRMTSERAPSPSS-RMGQAPSQSLLPPAQDQPRSPVPSAFSDQ 2458
Query: 423 TR-----KSRVSVSPGRTSGKV---TKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
+R + V+ S +SG V T G PAP ++ E G +
Sbjct: 2459 SRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQP 2518
Query: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
+A + Q + RR + SSS S SSSSS S S S+S
Sbjct: 2519 SALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSS--------------SGSSSSDSE 2564
Query: 535 KRQKETSPRGRRRRSPSPPPT-----RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589
P +R PSP P R R P P P R+RR+ + + S
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649
S S S S S + P P+ P+ P K PPP +R S
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKK------PPPGERRS--- 2675
Query: 650 KRRSPSLSSKHRKGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
RSP RK R +R + SP +R SP P PR Q+SSS RRG
Sbjct: 2676 --RSP------RKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRG----- 2722
Query: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741
QR S SPS + R TP P+ ++ +S SP
Sbjct: 2723 QRGDSRSPSHK---RRRETPSPRPMRHRSSRSP 2752
Score = 100 bits (250), Expect = 5e-21
Identities = 114/387 (29%), Positives = 158/387 (40%), Gaps = 44/387 (11%)
Query: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR 324
S E+ +T P R+ RSRT +PS +R R+ S S R +P + P
Sbjct: 2388 SAYERVSGRTSPPLLDRA--RSRTPPSAPSQSRMTSE---RAPSPSSRMGQAPSQSLLPP 2442
Query: 325 RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRS----------PPKKP 374
+ PR P +SR + + + S S SS + +++ S + P P
Sbjct: 2443 AQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVP 2502
Query: 375 PKRTSSPPRKTRRLSPSA----SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430
PP T PSA P + R S ++ + S + S+ + S S
Sbjct: 2503 HSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSD 2562
Query: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
S G +S V ++ SP+PAPK E E + +R++
Sbjct: 2563 SEG-SSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKR-------------KRRSS 2608
Query: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP 550
SSS S SSSSS S + S S S+SPSP K + P + SP
Sbjct: 2609 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP---KPASP 2665
Query: 551 SPPPTRRRRSPSPAPP-----PRRRRTPTPPPRRR-TPSPPPR-RRSPSPRRYSPPIQRR 603
PP RRS SP P R + +P RRR +P P PR ++S S R S QR
Sbjct: 2666 KKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRG 2725
Query: 604 YSPSPPPKRRTASPPPPPKR-RASPSP 629
S SP KRR +P P P R R+S SP
Sbjct: 2726 DSRSPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 91.7 bits (226), Expect = 3e-18
Identities = 114/441 (25%), Positives = 158/441 (35%), Gaps = 116/441 (26%)
Query: 148 DEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS 207
D + + SR ER+ SP R ++P S S P + +
Sbjct: 2403 DRARSRTPPSAPSQSRMTSERAPSPSSRMGQAP---------------SQSLLPPAQDQP 2447
Query: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQE---ATSTSD------ILKVPKP-EPIPEPK 257
RSP P+ + + + + S+ AT+TS +L VP P P +
Sbjct: 2448 RSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVG 2507
Query: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP------ 311
EP +++ +P RS S S + S S S + S S S S
Sbjct: 2508 EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSS 2567
Query: 312 ---------RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSS 362
+R PSP P+P+ R P P +P +R+RRSS+S S SSSSS
Sbjct: 2568 LPVQPEVALKRVPSP--TPAPKEAVREGRPPEP-------TPAKRKRRSSSSSSSSSSSS 2618
Query: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422
SSS S S +SS + S S+ P +P P A P P + P P + R
Sbjct: 2619 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPA---KPGPQALPKPASPKKPPPGE-RR 2674
Query: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482
+R R + R S ++ +R SP P+P
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP--------------------------- 2707
Query: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542
R Q SSS+ GS RR + SRS S
Sbjct: 2708 ----RDQQSSSSERGS--------------------RRGQRGDSRSPS------------ 2731
Query: 543 RGRRRRSPSPPPTRRRRSPSP 563
RRR +PSP P R R S SP
Sbjct: 2732 HKRRRETPSPRPMRHRSSRSP 2752
Score = 84.7 bits (208), Expect = 3e-16
Identities = 162/717 (22%), Positives = 257/717 (35%), Gaps = 102/717 (14%)
Query: 153 KRDKEEKESSREKRERSRSPR-----RRKSRSPSPRRRSSPVRRERKRSHSRSP---RHR 204
KR + + +R RSR+PR R +RSP RR S RS S +P R+
Sbjct: 2040 KRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNH 2099
Query: 205 TKSRSP-----------------SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKV 247
+ SR+P SP P + ++P + EP + P + ++
Sbjct: 2100 SGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDG 2159
Query: 248 PKPEPIPEPKEPSPEKNSKKEK--------EKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299
P P IP+ + S +N + + RP + + S+ P+ P
Sbjct: 2160 PGPR-IPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV-PL 2217
Query: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS----L 355
R+ + R P+ +P SR+P + AS +
Sbjct: 2218 MSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAV 2277
Query: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR-RLSPSASPPRRRHRPSPPATPP-PKTRH 413
+ S+ + + R+ + P +P L+ S +PP + PS TP P + +
Sbjct: 2278 APSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA----PKPRKVELSESEEDK 469
P+ ++ T + V+++ RT+ + T R +P+ + PR V LS E
Sbjct: 2338 LVGPRSAHAT--APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR-VPLSAYERVS 2394
Query: 470 GGKMAAA-DSVQQRR--QYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
G D + R Q++ +S + S SS + P +S + + + R PS
Sbjct: 2395 GRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQ-DQPRSPVPS 2453
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS---------PSPAPP----------- 566
+ S + T G + S T + P+P P
Sbjct: 2454 AFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPAST 2513
Query: 567 ----PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPP- 621
P P RR+ S S S S S S +S P P
Sbjct: 2514 GAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPE 2573
Query: 622 ---KRRASPSPPPKRRVSHSPPP--------KQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
KR SP+P PK V PP ++ SS + S S SS SS S S+
Sbjct: 2574 VALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSS 2633
Query: 671 REARSPQPNKRHSPSPRPRAPQTSSSP-------PPVRRGASSSPQR-----RQSPSPST 718
+ S + S SP P P + P PP S SP++ R S S S
Sbjct: 2634 SSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSY 2693
Query: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775
P+ R +P+P + +S S + RR R S SP ++ P P++ +S
Sbjct: 2694 SPVERRRPSPQPSPRDQQSSSSERGSRR--GQRGDSRSPSHKRRRETPSPRPMRHRS 2748
Score = 42.0 bits (97), Expect = 0.003
Identities = 35/92 (38%), Positives = 48/92 (52%), Gaps = 10/92 (10%)
Query: 140 KLASMKKQD--EDKDKRDKEEKESSREKRERSRSP--RRRKSRSPSPR--RRSSPVRRER 193
K AS KK E + + ++ +S R+ R S SP RRR S PSPR + SS R R
Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720
Query: 194 K--RSHSRSPRH--RTKSRSPSPAPEKKEKTP 221
+ R SRSP H R ++ SP P + ++P
Sbjct: 2721 RGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 157 bits (398), Expect = 3e-38
Identities = 191/731 (26%), Positives = 282/731 (38%), Gaps = 90/731 (12%)
Query: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259
SP+ +K S S AP P+P +K S + AT ++ P
Sbjct: 3 SPKRSSKP-SMSLAPSGSSMPTADPKPPASLK--STKSATPNRSLVPTKPATSRNSVMSP 59
Query: 260 SPEKNSKKEKEKE--KTRPRSRSRSKSRSRTRSRSPSHTRPRR-----------RHRSRS 306
S K++K K RP SRSR +S++RT SR + TR + R + S
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHS 119
Query: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPP----PPRHRRSRSPVRRRRRSSASLSGSSSSS 362
R +P RR S + SP R + P R+ P R R+P +++ S G +S
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
Query: 363 SSSRSRSPPKKPPKRTSSPPRKTR--RLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420
+ RS S P+ K++ PP + R S A P +P P + +P+P S
Sbjct: 180 NRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
Query: 421 NRTRK--------SRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
+ + S SP S +V + R P + R S S K
Sbjct: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
Query: 473 MAAADSVQQRRQYRRQNQ-------------QSSSDSGSSSSSEDERPKR--SHVKNGEV 517
+R R +++ QS S S S ++ P+R SH +
Sbjct: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
Query: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR-----RSPSPAPPPRRRRT 572
+ R HS SRS+S R + +SPR RS S P ++R RSP+ A R R+
Sbjct: 360 SKERSHSHSRSSSKE-RDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRS 418
Query: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR-----RTASPPPPPKRRASP 627
P R R+ S P + R SP R S S P + R+ SP R S
Sbjct: 419 PYKA-RDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSR 477
Query: 628 SPPPKRRVSH-SPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP--QPNKRHSP 684
SP +R S P K+R ++ S + + SS R R +RSP + +R S
Sbjct: 478 SPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSR 537
Query: 685 SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
SP ++ S P S + RQS SPS RR R+P K+ ++ S S
Sbjct: 538 SPNKERDRSQSRSP------SEEREHRQSRSPSKERDRRRWRSPS-KERERRQSRSSSEE 590
Query: 745 RRVSSSRS---VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
R S SRS SG P A S ++ S N S + K P+ S + PR+
Sbjct: 591 RDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQS-TVPRS 649
Query: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEE 861
D K+ + +++ K H +P+ + TL+Q++
Sbjct: 650 PDW-----KRSPTRTSSLSQNRTPSKTSSH--------------SPSTFPSGGQTLSQDD 690
Query: 862 PVAAPEPKKET 872
A K T
Sbjct: 691 SQADATTSKAT 701
Score = 137 bits (346), Expect = 3e-32
Identities = 176/620 (28%), Positives = 235/620 (37%), Gaps = 87/620 (14%)
Query: 163 REKRERSRSPRRRKSRSP--SPRRRSSPVRRERKRSHSRSPRHRTKSRSPS--------- 211
R R R+P RR SRS SP R S+P R R+H P ++ R+P+
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRASTP---GRIRTHGARPGMASRVRTPTSQQKGSRGK 171
Query: 212 ----PAPEKKEKTPELPEP-SVKVKEPS-------VQEATSTSDILKVPKPEPIPEPKE- 258
P +E++ P S K P E T K P IP ++
Sbjct: 172 SYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKS 231
Query: 259 --PSPEKNSK-----------KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
PSP + K +EK T SR +S +++ TRSR SH++ R RSR
Sbjct: 232 DNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSR 291
Query: 306 S----RSYSPRRRPSPRRRPS-PRRRTPPRRMPPPPRHRRSRSPVR----------RRRR 350
S R++S R S +R S R RT + RH +SRS + RR R
Sbjct: 292 SGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGR 351
Query: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
S S S S SRS K+ R SS PRK S S SP ++R + P K
Sbjct: 352 SHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR--SRSPNK 409
Query: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
R + + R S SP K + + SP A + D
Sbjct: 410 ARDRSRSRSPYKARDRSRSRSPN-------KARDCSRSRSPYKARDRSRSRSPNKARDHS 462
Query: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSR--- 527
+ + + R ++ S GS S D R RS K + + R S R
Sbjct: 463 RSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHR 522
Query: 528 -SASPSP-RKRQKETSPRGRRRRSPSPPPTRRR-----RSPSPAPPPRRRRTPTPPPRRR 580
S SPS R+R++ SP R RS S P+ R RSPS RR R+P+ RR
Sbjct: 523 RSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Query: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640
R S R SP Q YS + R +S R +PS S +
Sbjct: 583 QSRSSSEERDHSRSR-SPNKQSGYS-----RPRASSKEKAHSRSRTPSKEGNHSQSRTSS 636
Query: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSS---SP 697
+ S T RSP + SS S++ R+P HSPS P QT S S
Sbjct: 637 KESDPSQSTVPRSPDWKRSPTRTSSLSQN----RTPSKTSSHSPSTFPSGGQTLSQDDSQ 692
Query: 698 PPVRRGASSSPQRRQSPSPS 717
++ P R S S S
Sbjct: 693 ADATTSKATLPGERSSSSSS 712
Score = 127 bits (320), Expect = 4e-29
Identities = 159/710 (22%), Positives = 258/710 (36%), Gaps = 111/710 (15%)
Query: 142 ASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP 201
+SM D K K ++ + P ++ SP S KR+ S P
Sbjct: 19 SSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRP 78
Query: 202 ----RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK 257
R R+K+R+PS + +A+ SD+
Sbjct: 79 SSRSRVRSKARTPSRVS----------------TDTRTSKASKASDV------------- 109
Query: 258 EPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP 317
R + + +R R+P R RS SR+ +P R +
Sbjct: 110 ---------------------RCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTH 148
Query: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377
RP R R+P +++ S G +S+ RS S P+ K+
Sbjct: 149 GARPGMASRV--------------RTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKK 194
Query: 378 TSSPPRKT--RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
+ PP + R S A P +P P + +P+P S + + + P R
Sbjct: 195 SYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSR- 253
Query: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
+S SP +V+ + + + S RR +++ S
Sbjct: 254 ------------EKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSR 301
Query: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
S S + RS + G + + RHS SRS S + Q T RGR P
Sbjct: 302 VRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSK 361
Query: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
R S S + R + PR+ + R +S SP + + R + R+
Sbjct: 362 ERSHSHSRSSSKERDHRGSSSPRKES----GRSQSGSPNKQRDHSRSRSPNKARDRSRSR 417
Query: 616 SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS 675
SP R S SP R S S P ++ ++ RSP+ + H + SP+++ +RS
Sbjct: 418 SPYKARDRSRSRSPNKARDCSRSRSP-YKARDRSRSRSPNKARDHSRSRSPNKARDRSRS 476
Query: 676 PQPNKR--HSPSPRP------RAPQTSSSPPPVRRGASSSPQR--RQSPSPSTRPIRRVS 725
P+K HS P R ++ S R+ SSS +R R+S SPS RR S
Sbjct: 477 RSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQS 536
Query: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
R+P K+ ++ S SP R SRS S + ++ PS + + S + S
Sbjct: 537 RSPN-KERDRSQSRSPSEEREHRQSRSPSKERD---RRRWRSPSKERERRQSRSSSEERD 592
Query: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835
+++SP + Q G + + K+K H + + K H + +
Sbjct: 593 HSRSRSP---------NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSR 633
Score = 125 bits (315), Expect = 1e-28
Identities = 146/554 (26%), Positives = 221/554 (39%), Gaps = 78/554 (14%)
Query: 151 KDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSP 210
K+K D SSR+ + + + +S SP SS V+ + S P+ ++SRSP
Sbjct: 228 KEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSP 287
Query: 211 --SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKE 268
S + +K + S K + T + ++ + S + K
Sbjct: 288 RRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGR-------HSQSRSHSKGKS 340
Query: 269 KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTP 328
+ + +T R RS + SR+ ++ RS SH+R + R S SPR+ + SP ++
Sbjct: 341 QNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRD 400
Query: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL 388
H RSRSP + R R SRSRSP K + S P K R
Sbjct: 401 ---------HSRSRSPNKARDR--------------SRSRSPYKARDRSRSRSPNKARDC 437
Query: 389 SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS-----GKVTKHK 443
S S SP + R R + P K R + N+ R S SP + G +K +
Sbjct: 438 SRSRSPYKARDRSR--SRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKER 495
Query: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
+ SPS + R+ S E D + + +QRRQ R N++ S S S SE
Sbjct: 496 DHRRSRSPSKERQCRQSRSSSKERDH-RRSRSPSKERQRRQSRSPNKERDR-SQSRSPSE 553
Query: 504 DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563
+ ++S + E RRR SPS+ R+R++ S R S S P ++ S
Sbjct: 554 EREHRQSRSPSKERDRRRWRSPSKE-----RERRQSRSSSEERDHSRSRSPNKQ----SG 604
Query: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
PR R RTPS + +S S RT+S P +
Sbjct: 605 YSRPRASSKEKAHSRSRTPSK----------------EGNHSQS-----RTSSKESDPSQ 643
Query: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPS-RSTREARSPQPNKRH 682
P P +R SP R+S +++ R+PS +S H + PS T Q +
Sbjct: 644 STVPRSPDWKR---SP---TRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATT 697
Query: 683 SPSPRPRAPQTSSS 696
S + P +SSS
Sbjct: 698 SKATLPGERSSSSS 711
Score = 111 bits (278), Expect = 3e-24
Identities = 130/449 (28%), Positives = 184/449 (40%), Gaps = 51/449 (11%)
Query: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRER-KRS 196
+EK S + ++ S + +SRSPRR SRS S +R S VR KR+
Sbjct: 253 REKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRR--SRSGSQKRTHSRVRSHSWKRN 310
Query: 197 HSRSPRHRTK------------SRSPSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTSD 243
HSR+ R RT+ SRS S + + +TP + PS + + S S
Sbjct: 311 HSRA-RSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSR 369
Query: 244 ILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
+ ++ K++ RSRS +K+R R+RSRSP + R R
Sbjct: 370 SSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY----KARDR 425
Query: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR-HRRSRSPVRRRRRSSASLSGSSSSS 362
SRSRS + R S R P R R P R H RSRSP + R RS + S
Sbjct: 426 SRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRS--RSPSKER 483
Query: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR-HRPSPPATPPPKTRHSPTPQQSN 421
S+ SP K+ R S P K R+ S S + R HR S P K R + N
Sbjct: 484 DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS---RSPSKERQRRQSRSPN 540
Query: 422 RTRKSRVSVSPG-----RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED-------- 468
+ R S SP R S +K + + SPS + R+ S E D
Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPN 600
Query: 469 --KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
G A S ++ R + + S S +SS++ P +S V +R SP+
Sbjct: 601 KQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKR---SPT 657
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPT 555
R++S S + +TS SPS P+
Sbjct: 658 RTSSLSQNRTPSKTS-----SHSPSTFPS 681
Score = 103 bits (256), Expect = 9e-22
Identities = 105/343 (30%), Positives = 147/343 (42%), Gaps = 44/343 (12%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPR------RRKSRSPS 181
KE + K + + +RD S + R+RSRS R +SRSP+
Sbjct: 373 KERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPN 432
Query: 182 PRR---RSSPVRRERKRSHSRSP---RHRTKSRSPSPA--------PEKKEKTPELPEPS 227
R RS + R RS SRSP R ++SRSP+ A P K+ +L PS
Sbjct: 433 KARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492
Query: 228 VKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK--EKEKTRPRSRSRSKSR 285
KE + + S S K + + S E++ ++ + KE+ R +SRS +K R
Sbjct: 493 ---KERDHRRSRSPS------KERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543
Query: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345
R++SRSPS R R+ RS S+ RR SP + R R R H RSRSP
Sbjct: 544 DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE---RERRQSRSSSEERDHSRSRSP- 599
Query: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKK---PPKRTSS----PPRKTRRLSPS-ASPPRR 397
++ + SS + SRSR+P K+ RTSS P + T SP P R
Sbjct: 600 -NKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTR 658
Query: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
S TP + HSP+ S S+ T+ K T
Sbjct: 659 TSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKAT 701
Score = 102 bits (254), Expect = 2e-21
Identities = 116/394 (29%), Positives = 165/394 (41%), Gaps = 67/394 (17%)
Query: 132 KQRQIEQEKLASMKKQDEDKDKRDKE----EKESSREKRE--RSRSPR--RRKSRSPSP- 182
K+R + +S ++ KE + S ++R+ RSRSP R +SRS SP
Sbjct: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
Query: 183 ----RRRSSPVRRERKRSHSRSP---RHRTKSRSPSPAPE-KKEKTPELPEPSVKVKEPS 234
R RS + R S SRSP R R++SRSP+ A + + ++P + + PS
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480
Query: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRP--RSRSRSKSRSRTRSRS 292
+ S + PS E++ ++ + K R +SRS SK R RSRS
Sbjct: 481 KERDHS--------------QLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 293 PSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS-RSPVRRRRRS 351
PS R RR +SRS + R S R PS R R P R RR RSP + R R
Sbjct: 527 PSKERQRR----QSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERR 582
Query: 352 SASLSGSSSSSSSSRSRSPPKKP----PKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407
+ SS SRSRSP K+ P+ +S +R +PS + R S +
Sbjct: 583 QS--RSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESD 640
Query: 408 PPKTRHSPTPQ-QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466
P ++ +P + + TR S S+S RT K + H SPS P
Sbjct: 641 PSQSTVPRSPDWKRSPTRTS--SLSQNRTPSKTSSH-------SPSTFP----------- 680
Query: 467 EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
GG+ + D Q + S SSS
Sbjct: 681 --SGGQTLSQDDSQADATTSKATLPGERSSSSSS 712
Score = 102 bits (254), Expect = 2e-21
Identities = 101/330 (30%), Positives = 142/330 (43%), Gaps = 39/330 (11%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRE--RSRSPR----RRKSRSPS 181
K+ R K + RD+ S + R+ RSRSP R +SRSP+
Sbjct: 397 KQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPN 456
Query: 182 PRR---RSSPVRRERKRSHSRSP-RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
R RS + R RS SRSP + R S+ SP+ E+ + P KE ++
Sbjct: 457 KARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPS-----KERQCRQ 511
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS--RSRTRSRSPSH 295
+ S+S K + PS E+ ++ + K R RS+SRS S R +SRSPS
Sbjct: 512 SRSSS------KERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSK 565
Query: 296 TRPRRRHRSRSRSYSPRR-RPSPRRRPSPRRRTP--------PRRMPPPPRHRRSRSPVR 346
R RRR RS S+ R+ R S R R R+P PR H RSR+P +
Sbjct: 566 ERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSK 625
Query: 347 RRRRS-SASLSGSSSSSSSSRSRSPP-KKPPKRTSS-----PPRKTRRLSPSASPPRRRH 399
S S + S S S S+ RSP K+ P RTSS P KT SPS P +
Sbjct: 626 EGNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQT 685
Query: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVS 429
+ T + P + + + S+++
Sbjct: 686 LSQDDSQADATTSKATLPGERSSSSSSKLA 715
Score = 94.7 bits (234), Expect = 3e-19
Identities = 129/558 (23%), Positives = 224/558 (40%), Gaps = 93/558 (16%)
Query: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
S +R + S SL+ S SS ++ + P ++++P R P+ S S
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSS 61
Query: 403 PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS-----GKVTK--------HKGTEKR- 448
+T T+ +P+ + S+R+R + +P R S K +K +GT R
Sbjct: 62 SKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTHSRG 121
Query: 449 ------------ESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
SPS A P ++ + ++ S Q+ + + + +S+
Sbjct: 122 RTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTSNR 181
Query: 497 GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS-PRGRRRRSPSPPPT 555
S S K+S+ G G R S + +PS K Q T P + +PSP +
Sbjct: 182 ERSDSQPRNLSKKSYRPPGGSGIGR--SSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
Query: 556 RRRRSPSPAPPPRRRRTPTPP-----------------PRRRTPSPPPRR-RSPSPRRYS 597
R+ +S P R ++ +P P+ + S PRR RS S +R
Sbjct: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTH 299
Query: 598 PPI-----QRRYSPSPPPKRR---------TASPPPPPKRRASPSPPPKRRVSHS---PP 640
+ +R +S + R+ + S + + S P+R SH+ P
Sbjct: 300 SRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNP 359
Query: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
K+RS + RS S HR SSP + + ++S PNK+ S R R+P +
Sbjct: 360 SKERSH--SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHS-RSRSPNKARD---- 412
Query: 701 RRGASSSPQRRQSPSPSTRP--IRRVSRTPEPKKIK-KAASPSPQSVRRVSSSRSVSGSP 757
R S SP + + S S P R SR+ P K + ++ S SP R S SRS + +
Sbjct: 413 -RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKAR 471
Query: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDK 817
+ + + SP + + S SP+ +S +PS K+++ ++ +
Sbjct: 472 DRSRSR-----SPSKERDHSQLGSPSKERDHRRSRSPS-------------KERQCRQSR 513
Query: 818 KHKKDKKHKKHKKHKKEK 835
K++ H++ + KE+
Sbjct: 514 SSSKERDHRRSRSPSKER 531
Score = 76.3 bits (186), Expect = 1e-13
Identities = 71/267 (26%), Positives = 117/267 (43%), Gaps = 40/267 (14%)
Query: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRS 179
P+ + + ++ + +L S K+ + + R ++ R+ R S+ R+SRS
Sbjct: 467 PNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRS 526
Query: 180 PS---PRRRSSPVRRERKRSHSRSP---RHRTKSRSPSPAPEKKE-KTPELPEPSVKVKE 232
PS RR+S +ER RS SRSP R +SRSPS +++ ++P KE
Sbjct: 527 PSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPS--------KE 578
Query: 233 PSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRS 292
+++ S+S E ++ S ++ K+ + R S+ ++ SRSRT S+
Sbjct: 579 RERRQSRSSS------------EERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKE 626
Query: 293 PSHTRPRRRHRSRSRSY-----SPRRRPSPRRRPS-PRRRTP-------PRRMPPPPRHR 339
+H++ R + S SP + SP R S + RTP P P +
Sbjct: 627 GNHSQSRTSSKESDPSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTL 686
Query: 340 RSRSPVRRRRRSSASLSGSSSSSSSSR 366
S A+L G SSSSSS+
Sbjct: 687 SQDDSQADATTSKATLPGERSSSSSSK 713
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 146 bits (369), Expect = 7e-35
Identities = 163/811 (20%), Positives = 299/811 (36%), Gaps = 93/811 (11%)
Query: 153 KRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSP 212
K+ K+ ES E S S + S S S SS +R+ + +S + R K
Sbjct: 102 KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD 161
Query: 213 APEKKEKTPELPEPSV-------------KVKEP--SVQEATSTSDILKVPKPEPI-PEP 256
+ + K P+P V KV P S + S K+ +PI P P
Sbjct: 162 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 221
Query: 257 KEPSPEKNSKKE-----------KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
P P ++ KE + KE T ++ + + +T S + + + +
Sbjct: 222 SLP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 306 SRSYSPRRRPSPRRRPS---PRRRTPPRRMPPPPRHRRS---RSPVRRRRRSSASLSGSS 359
+ + +P+P+ + P TP P P+ S + P +S+ +
Sbjct: 281 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 340
Query: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS------PPRRRHRPSPPATPPPKTRH 413
+ +++ + + PK+P T+ P T P+ + P + P+ P P P T
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 400
Query: 414 SP---TPQQSNRTRKSRVSVSPGRTSGKVTKHKG--TEKRESPSPAPKPRKVELSESEED 468
P TP++ T + + + TK T K +P+ KP E
Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+ A + + ++ +++ S +++ E P + K+ + SP+ +
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE---PAPTTTKSAPT-TPKEPSPTTT 516
Query: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS-PAPPPRRRRTPTPP-------PRRR 580
P+P KE +P ++ +P+ P +P PAP ++ PT P P+
Sbjct: 517 KEPAPTT-PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 575
Query: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-PKRRASPSPP-PKRRVSHS 638
P+ P + +P + +P + +P+ P + +P P P P+P PK ++
Sbjct: 576 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 635
Query: 639 PP------PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
P PK+ + K +P+ + + + + P P P+P+ AP
Sbjct: 636 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695
Query: 693 TSSSP---------PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743
T+ P P +G + + + +P+ P + P +K+ A +P+
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755
Query: 744 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
+ + + P PAP +P ++ +P+T PA K +PT +PP +
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTTS 814
Query: 804 QEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV-----AAAAAAAVTPAAIAAATTTLA 858
+ K+ D+ + KA+ TPAA TT A
Sbjct: 815 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 874
Query: 859 Q------------EEPVAAPEPKKETESEAE 877
+ E AAP+ KET + E
Sbjct: 875 KDKTTERDLRTTPETTTAAPKMTKETATTTE 905
Score = 117 bits (293), Expect = 5e-26
Identities = 154/827 (18%), Positives = 294/827 (35%), Gaps = 75/827 (9%)
Query: 132 KQRQIEQEKLASMKKQD--EDKDKRDKEEKESSREKRE-RSRSPRRRKSRSPSPRRRSS- 187
K+ +E ++ + KQ + K+K ++ S EK + +P + P+P+ ++
Sbjct: 239 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 298
Query: 188 --PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL 245
P K +P+ + P P + P P KEP+ S
Sbjct: 299 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP------KEPAPTTTKSAPTTP 352
Query: 246 KVPKP----EPIPE-PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
K P P EP P PKEP+P + K+ P + K + T + P+ T P+
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT---PKEPAPTTPKKPAPTTPKE 409
Query: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
+ + +P + + P+P + P P P + P + A +
Sbjct: 410 PAPTTPKEPTP----TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 465
Query: 361 SSSSSRSRSP--PKKP-PKRTSSPPRKTRRLSPSA--SPPRRRHRPSPPAT--PPPKTRH 413
+ ++++ SP PK+P P T S P T+ +P+ S P PSP T P P T
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 414 SPTPQQSNR----TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
P P + T K +P + TK + P+P + +
Sbjct: 526 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 585
Query: 470 GGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
A + ++ + + + + + E P + K + +P+
Sbjct: 586 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 645
Query: 530 SPSPRKRQ-------KETSPRGRRRRSPSP-----PPTRRRRSPSPAPPPRRRRTPTPPP 577
P+P + KET+P + +P+ P T ++ +P P + +
Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705
Query: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----PKRRTASPPPPPKRRASPSPPPKR 633
+ P+ P +P+ +P + +P+ P P P PK+ A P
Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765
Query: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR---STREARSPQPNKRHSP------ 684
+ + +P T + + + K ++P + +T E P ++ +P
Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 825
Query: 685 -----SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRR--VSRTPEPKKIKKAA 737
SP P+ S+ P P + +SP+ P+ T + ++ T + K ++
Sbjct: 826 TTIHKSPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 883
Query: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797
+P++ ++ + + K + + +Q ST P K T + +
Sbjct: 884 RTTPETT--TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTL 857
P + ++ + K ++ K K + K K A P + T
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMP 1000
Query: 858 AQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904
+P P P+K T + E N + E L++ + +P S
Sbjct: 1001 RVRKPKTTPTPRKMTSTMPELN---PTSRIAEAMLQTTTRPNQTPNS 1044
Score = 114 bits (286), Expect = 3e-25
Identities = 147/744 (19%), Positives = 267/744 (35%), Gaps = 72/744 (9%)
Query: 178 RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
++P P S ++ KRS P P K+KT ++ E +E SV E
Sbjct: 77 KAPPPSGASQTIKSTTKRS---------------PKPPNKKKTKKVIESEEITEEHSVSE 121
Query: 238 ----------ATSTSDILKVPKPEPIPEPKEPSPE---KNSKKEKEKEKTRPRSRSRSKS 284
++S+S I K+ + +E + K++KK + K+K P+ ++
Sbjct: 122 NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 181
Query: 285 RSRT-----RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
S + +P + + S S + + +PR P T +
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 241
Query: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
+ S G ++S+ ++S K K + + + +P A +
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 301
Query: 400 RPSPPATPPPKTRHSP---TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE-----SP 451
+ P P P T P TP++ T +P + TK T +E +
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 361
Query: 452 SPAP-KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
PAP P++ + ++E +A + + + + + + + + P +
Sbjct: 362 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 511 HVKNGEVGRRRRHSPSRSASPSPR--KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP-- 566
K + +P+ P+P K+ T+P+ +P P + PSP P
Sbjct: 422 TPKE-PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480
Query: 567 PRRRRTPTPPPRRRTPSPPPRRRSP-SPRRYSPPIQRRYSPSPP-------PKRRTASPP 618
P T + P + P+P + +P +P+ SP + +P+ P PK+ + P
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540
Query: 619 PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR---STREARS 675
P P P +P + +P T + + + K ++P + +T E +
Sbjct: 541 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 600
Query: 676 PQPNKRHSP-SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST--RPIRRVSRTPEPKK 732
P + +P +P P T P P A ++P + P+P+T P + P P
Sbjct: 601 PTTPEELAPTTPEEPTPTTPEEPAPTTPKA-AAPNTPKEPAPTTPKEPAPTTPKEPAPTT 659
Query: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP----PSPVQSQSPSTNWSPAVPVKK 788
K+ A +P+ ++ + P P K PAP P+ + + +T PA K
Sbjct: 660 PKETAPTTPK-----GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714
Query: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPA 848
+PT P + +E K K+ K KE A T
Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST-T 773
Query: 849 AIAAATTTLAQEEPVAAPEPKKET 872
+ A TT + P EP T
Sbjct: 774 SDKPAPTTPKETAPTTPKEPAPTT 797
Score = 112 bits (280), Expect = 2e-24
Identities = 131/609 (21%), Positives = 231/609 (37%), Gaps = 79/609 (12%)
Query: 309 YSPRRRPSPRRRPSPRR-----RTPPRRMPPPPRHRRSRSPVRRRRRSSA-SLSGSSSSS 362
++P PS ++ P P ++ +R P PP ++++ + + S+S + SS
Sbjct: 67 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 126
Query: 363 SSSRSRSPP----KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP---------P 409
SSS S S K + S+ R+ ++ + R + P PP
Sbjct: 127 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 186
Query: 410 KTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES-PSPAPKPRKVELSESEED 468
T ++ T+ ++VS SP K+T K R S P + ++ L+ ++E
Sbjct: 187 NGDFKVTTPDTSTTQHNKVSTSP-----KITTAKPINPRPSLPPNSDTSKETSLTVNKE- 240
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+ + ++ N+Q+S+D ++S E ++ E + +P+
Sbjct: 241 ---------TTVETKETTTTNKQTSTDGKEKTTSAKE------TQSIEKTSAKDLAPTSK 285
Query: 529 --ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT----PPPRRRTP 582
A P+P+ ET+ +G +P P + P+ P + TPT P + P
Sbjct: 286 VLAKPTPK---AETTTKGPALTTPKEPTPTTPKEPASTTP--KEPTPTTIKSAPTTPKEP 340
Query: 583 SPPPRRRSP-SPRRYSPPIQRRYSPSPP--PKRRTASPPPPPKRRASPSPPPKRRVSHSP 639
+P + +P +P+ +P + +P+ P P T P P +++P+ P + +P
Sbjct: 341 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE----PAP 396
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP---SPRPRAPQTSSS 696
++ +P T + + K ++P + P P P +P+ AP T
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456
Query: 697 PPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS----PSPQSVRRVSSSRS 752
P P +P + PSP+T + P P K A + P+P + + S+ +
Sbjct: 457 PAPT-TPKEPAPTTTKEPSPTT------PKEPAPTTTKSAPTTTKEPAPTTTK---SAPT 506
Query: 753 VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT--PSPSPPRNSDQEGGGKK 810
P P K PAP +P + +P+T PA K +PT P+P K
Sbjct: 507 TPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565
Query: 811 KKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKK 870
+ K KK EK A TT + P EP
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625
Query: 871 ETESEAEDN 879
T A N
Sbjct: 626 TTPKAAAPN 634
Score = 89.4 bits (220), Expect = 1e-17
Identities = 136/714 (19%), Positives = 244/714 (34%), Gaps = 123/714 (17%)
Query: 178 RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK---TPELPEPSVKVKEPS 234
+ P+P P K +P+ T + PAP KE TP+ P P+ K
Sbjct: 392 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 235 VQEATSTSDILKVPKP----EPIPE-PKEPSPEKNSKKEKEKEKTRPRSRSRS----KSR 285
K P P EP P PKEP+P ++ P + + K
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPR----------RRPSPRRRPSPRRRTPPRRMPPP 335
S T ++ P+ T P+ + + +P + P+P P TP P
Sbjct: 512 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 571
Query: 336 PRHRRSRSPVRRRRRSSASLSGSSSS--SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
P+ +P + + L+ ++ + ++ P P + T + P + +P A+
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 631
Query: 394 PPRRRHRPSP--PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP 451
P P+P P P P T P P T K +P T+ K + P
Sbjct: 632 APNTPKEPAPTTPKEPAPTTPKEPAPT----TPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Query: 452 SP---APKPRKVELSESEEDKGG----KMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
+P AP K E + + DK K A + ++ + ++ G++ ++
Sbjct: 688 APKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 746
Query: 505 E----RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
E PK+ K + + + S P+P KET+P + +P+ P +
Sbjct: 747 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTT 805
Query: 561 PSPAPP-------PRRRRTPTP---PPRRRTPS----PPPRRRSPSPRRYSPPIQRRYSP 606
P PP P + PT P TP P P+ SP+ P + +
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Query: 607 SPP------------------PKRRTASPPPPPKRRASPSPPPKRRVSHSPPP-----KQ 643
+ P P+ TA+P + + + +++ + Q
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925
Query: 644 RSSP--VTKRRSPSLSSK----------------------------HRKGSSPS--RSTR 671
++P +T ++ +L+ K + K ++P + T+
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 985
Query: 672 EARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731
+ P K+ PR R P+T + +P++ S P P R++
Sbjct: 986 APKKPTSTKKPKTMPRVRKPKT-----------TPTPRKMTSTMPELNPTSRIAEAMLQT 1034
Query: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
+ +P+ + V S G+ P + +P ++ P VP
Sbjct: 1035 TTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 1088
Score = 75.9 bits (185), Expect = 2e-13
Identities = 96/461 (20%), Positives = 167/461 (36%), Gaps = 57/461 (12%)
Query: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVK 229
+ P + P+P P K + +P+ + PAP TP+ P P +
Sbjct: 637 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT----TPKKPAPK-E 691
Query: 230 VKEPSVQEATSTS---DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
+ + +E TST+ PK PKEP+P KE T P K +
Sbjct: 692 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTP------KGTA 741
Query: 287 RTRSRSPSHTRPRRRH-------RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
T + P+ T P++ ++ + + +P+P TP P P+
Sbjct: 742 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801
Query: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
+P ++S + + K+P SP T LS +P +
Sbjct: 802 APTTP-----------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 850
Query: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459
P P P KT + P+ + T K + + RT+ + T + APK K
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETT-----------TAAPKMTK 898
Query: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
+ +E+ K+ A + + Q ++ ++ + PK + K
Sbjct: 899 ETATTTEKTTESKITATTT----QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 954
Query: 520 RRRHSPSRSASPSPR-KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR 578
+ P +A P R K T+P+ ++ PT ++ P P R+ +T TP PR
Sbjct: 955 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK-PKTMPRVRKPKT-TPTPR 1012
Query: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
+ T + P +P+ R +Q P+ P + P
Sbjct: 1013 KMTSTMP--ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 1051
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 146 bits (369), Expect = 7e-35
Identities = 163/811 (20%), Positives = 299/811 (36%), Gaps = 93/811 (11%)
Query: 153 KRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSP 212
K+ K+ ES E S S + S S S SS +R+ + +S + R K
Sbjct: 143 KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKD 202
Query: 213 APEKKEKTPELPEPSV-------------KVKEP--SVQEATSTSDILKVPKPEPI-PEP 256
+ + K P+P V KV P S + S K+ +PI P P
Sbjct: 203 NKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRP 262
Query: 257 KEPSPEKNSKKE-----------KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305
P P ++ KE + KE T ++ + + +T S + + + +
Sbjct: 263 SLP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 306 SRSYSPRRRPSPRRRPS---PRRRTPPRRMPPPPRHRRS---RSPVRRRRRSSASLSGSS 359
+ + +P+P+ + P TP P P+ S + P +S+ +
Sbjct: 322 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 381
Query: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS------PPRRRHRPSPPATPPPKTRH 413
+ +++ + + PK+P T+ P T P+ + P + P+ P P P T
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 441
Query: 414 SP---TPQQSNRTRKSRVSVSPGRTSGKVTKHKG--TEKRESPSPAPKPRKVELSESEED 468
P TP++ T + + + TK T K +P+ KP E
Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+ A + + ++ +++ S +++ E P + K+ + SP+ +
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE---PAPTTTKSAPT-TPKEPSPTTT 557
Query: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS-PAPPPRRRRTPTPP-------PRRR 580
P+P KE +P ++ +P+ P +P PAP ++ PT P P+
Sbjct: 558 KEPAPTT-PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 616
Query: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP-PKRRASPSPP-PKRRVSHS 638
P+ P + +P + +P + +P+ P + +P P P P+P PK ++
Sbjct: 617 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 676
Query: 639 PP------PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ 692
P PK+ + K +P+ + + + + P P P+P+ AP
Sbjct: 677 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736
Query: 693 TSSSP---------PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS 743
T+ P P +G + + + +P+ P + P +K+ A +P+
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796
Query: 744 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
+ + + P PAP +P ++ +P+T PA K +PT +PP +
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTTS 855
Query: 804 QEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV-----AAAAAAAVTPAAIAAATTTLA 858
+ K+ D+ + KA+ TPAA TT A
Sbjct: 856 EVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTA 915
Query: 859 Q------------EEPVAAPEPKKETESEAE 877
+ E AAP+ KET + E
Sbjct: 916 KDKTTERDLRTTPETTTAAPKMTKETATTTE 946
Score = 117 bits (293), Expect = 5e-26
Identities = 154/827 (18%), Positives = 294/827 (35%), Gaps = 75/827 (9%)
Query: 132 KQRQIEQEKLASMKKQD--EDKDKRDKEEKESSREKRE-RSRSPRRRKSRSPSPRRRSS- 187
K+ +E ++ + KQ + K+K ++ S EK + +P + P+P+ ++
Sbjct: 280 KETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTT 339
Query: 188 --PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL 245
P K +P+ + P P + P P KEP+ S
Sbjct: 340 KGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTP------KEPAPTTTKSAPTTP 393
Query: 246 KVPKP----EPIPE-PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
K P P EP P PKEP+P + K+ P + K + T + P+ T P+
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT---PKEPAPTTPKKPAPTTPKE 450
Query: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
+ + +P + + P+P + P P P + P + A +
Sbjct: 451 PAPTTPKEPTP----TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP 506
Query: 361 SSSSSRSRSP--PKKP-PKRTSSPPRKTRRLSPSA--SPPRRRHRPSPPAT--PPPKTRH 413
+ ++++ SP PK+P P T S P T+ +P+ S P PSP T P P T
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 414 SPTPQQSNR----TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK 469
P P + T K +P + TK + P+P + +
Sbjct: 567 EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTP 626
Query: 470 GGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSA 529
A + ++ + + + + + E P + K + +P+
Sbjct: 627 TTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPK 686
Query: 530 SPSPRKRQ-------KETSPRGRRRRSPSP-----PPTRRRRSPSPAPPPRRRRTPTPPP 577
P+P + KET+P + +P+ P T ++ +P P + +
Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746
Query: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP----PKRRTASPPPPPKRRASPSPPPKR 633
+ P+ P +P+ +P + +P+ P P P PK+ A P
Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806
Query: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR---STREARSPQPNKRHSP------ 684
+ + +P T + + + K ++P + +T E P ++ +P
Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEP 866
Query: 685 -----SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRR--VSRTPEPKKIKKAA 737
SP P+ S+ P P + +SP+ P+ T + ++ T + K ++
Sbjct: 867 TTIHKSPDESTPELSAEPTP--KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDL 924
Query: 738 SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797
+P++ ++ + + K + + +Q ST P K T + +
Sbjct: 925 RTTPETT--TAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 798 PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTL 857
P + ++ + K ++ K K + K K A P + T
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKP-QKPTKAPKKPTSTKKPKTMP 1041
Query: 858 AQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904
+P P P+K T + E N + E L++ + +P S
Sbjct: 1042 RVRKPKTTPTPRKMTSTMPELN---PTSRIAEAMLQTTTRPNQTPNS 1085
Score = 114 bits (286), Expect = 3e-25
Identities = 147/744 (19%), Positives = 267/744 (35%), Gaps = 72/744 (9%)
Query: 178 RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
++P P S ++ KRS P P K+KT ++ E +E SV E
Sbjct: 118 KAPPPSGASQTIKSTTKRS---------------PKPPNKKKTKKVIESEEITEEHSVSE 162
Query: 238 ----------ATSTSDILKVPKPEPIPEPKEPSPE---KNSKKEKEKEKTRPRSRSRSKS 284
++S+S I K+ + +E + K++KK + K+K P+ ++
Sbjct: 163 NQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA 222
Query: 285 RSRT-----RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
S + +P + + S S + + +PR P T +
Sbjct: 223 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 282
Query: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
+ S G ++S+ ++S K K + + + +P A +
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP 342
Query: 400 RPSPPATPPPKTRHSP---TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE-----SP 451
+ P P P T P TP++ T +P + TK T +E +
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTK 402
Query: 452 SPAP-KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
PAP P++ + ++E +A + + + + + + + + P +
Sbjct: 403 EPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 511 HVKNGEVGRRRRHSPSRSASPSPR--KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPP-- 566
K + +P+ P+P K+ T+P+ +P P + PSP P
Sbjct: 463 TPKE-PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521
Query: 567 PRRRRTPTPPPRRRTPSPPPRRRSP-SPRRYSPPIQRRYSPSPP-------PKRRTASPP 618
P T + P + P+P + +P +P+ SP + +P+ P PK+ + P
Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581
Query: 619 PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR---STREARS 675
P P P +P + +P T + + + K ++P + +T E +
Sbjct: 582 KEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 641
Query: 676 PQPNKRHSP-SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPST--RPIRRVSRTPEPKK 732
P + +P +P P T P P A ++P + P+P+T P + P P
Sbjct: 642 PTTPEELAPTTPEEPTPTTPEEPAPTTPKA-AAPNTPKEPAPTTPKEPAPTTPKEPAPTT 700
Query: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP----PSPVQSQSPSTNWSPAVPVKK 788
K+ A +P+ ++ + P P K PAP P+ + + +T PA K
Sbjct: 701 PKETAPTTPK-----GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755
Query: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPA 848
+PT P + +E K K+ K KE A T
Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTST-T 814
Query: 849 AIAAATTTLAQEEPVAAPEPKKET 872
+ A TT + P EP T
Sbjct: 815 SDKPAPTTPKETAPTTPKEPAPTT 838
Score = 112 bits (280), Expect = 2e-24
Identities = 131/609 (21%), Positives = 231/609 (37%), Gaps = 79/609 (12%)
Query: 309 YSPRRRPSPRRRPSPRR-----RTPPRRMPPPPRHRRSRSPVRRRRRSSA-SLSGSSSSS 362
++P PS ++ P P ++ +R P PP ++++ + + S+S + SS
Sbjct: 108 HNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESS 167
Query: 363 SSSRSRSPP----KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP---------P 409
SSS S S K + S+ R+ ++ + R + P PP
Sbjct: 168 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 227
Query: 410 KTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES-PSPAPKPRKVELSESEED 468
T ++ T+ ++VS SP K+T K R S P + ++ L+ ++E
Sbjct: 228 NGDFKVTTPDTSTTQHNKVSTSP-----KITTAKPINPRPSLPPNSDTSKETSLTVNKE- 281
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+ + ++ N+Q+S+D ++S E ++ E + +P+
Sbjct: 282 ---------TTVETKETTTTNKQTSTDGKEKTTSAKE------TQSIEKTSAKDLAPTSK 326
Query: 529 --ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT----PPPRRRTP 582
A P+P+ ET+ +G +P P + P+ P + TPT P + P
Sbjct: 327 VLAKPTPK---AETTTKGPALTTPKEPTPTTPKEPASTTP--KEPTPTTIKSAPTTPKEP 381
Query: 583 SPPPRRRSP-SPRRYSPPIQRRYSPSPP--PKRRTASPPPPPKRRASPSPPPKRRVSHSP 639
+P + +P +P+ +P + +P+ P P T P P +++P+ P + +P
Sbjct: 382 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE----PAP 437
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSP---SPRPRAPQTSSS 696
++ +P T + + K ++P + P P P +P+ AP T
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497
Query: 697 PPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAAS----PSPQSVRRVSSSRS 752
P P +P + PSP+T + P P K A + P+P + + S+ +
Sbjct: 498 PAPT-TPKEPAPTTTKEPSPTT------PKEPAPTTTKSAPTTTKEPAPTTTK---SAPT 547
Query: 753 VSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPT--PSPSPPRNSDQEGGGKK 810
P P K PAP +P + +P+T PA K +PT P+P K
Sbjct: 548 TPKEPSPTTTKEPAPTTP-KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606
Query: 811 KKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKK 870
+ K KK EK A TT + P EP
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666
Query: 871 ETESEAEDN 879
T A N
Sbjct: 667 TTPKAAAPN 675
Score = 89.4 bits (220), Expect = 1e-17
Identities = 136/714 (19%), Positives = 244/714 (34%), Gaps = 123/714 (17%)
Query: 178 RSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK---TPELPEPSVKVKEPS 234
+ P+P P K +P+ T + PAP KE TP+ P P+ K
Sbjct: 433 KEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 235 VQEATSTSDILKVPKP----EPIPE-PKEPSPEKNSKKEKEKEKTRPRSRSRS----KSR 285
K P P EP P PKEP+P ++ P + + K
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPR----------RRPSPRRRPSPRRRTPPRRMPPP 335
S T ++ P+ T P+ + + +P + P+P P TP P
Sbjct: 553 SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT 612
Query: 336 PRHRRSRSPVRRRRRSSASLSGSSSS--SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
P+ +P + + L+ ++ + ++ P P + T + P + +P A+
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAA 672
Query: 394 PPRRRHRPSP--PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP 451
P P+P P P P T P P T K +P T+ K + P
Sbjct: 673 APNTPKEPAPTTPKEPAPTTPKEPAPT----TPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Query: 452 SP---APKPRKVELSESEEDKGG----KMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
+P AP K E + + DK K A + ++ + ++ G++ ++
Sbjct: 729 APKELAPTTTK-EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLK 787
Query: 505 E----RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
E PK+ K + + + S P+P KET+P + +P+ P +
Sbjct: 788 EPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTT 846
Query: 561 PSPAPP-------PRRRRTPTP---PPRRRTPS----PPPRRRSPSPRRYSPPIQRRYSP 606
P PP P + PT P TP P P+ SP+ P + +
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Query: 607 SPP------------------PKRRTASPPPPPKRRASPSPPPKRRVSHSPPP-----KQ 643
+ P P+ TA+P + + + +++ + Q
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966
Query: 644 RSSP--VTKRRSPSLSSK----------------------------HRKGSSPS--RSTR 671
++P +T ++ +L+ K + K ++P + T+
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 1026
Query: 672 EARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731
+ P K+ PR R P+T + +P++ S P P R++
Sbjct: 1027 APKKPTSTKKPKTMPRVRKPKT-----------TPTPRKMTSTMPELNPTSRIAEAMLQT 1075
Query: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
+ +P+ + V S G+ P + +P ++ P VP
Sbjct: 1076 TTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLLRPHVFMPEVTPDMDYLPRVP 1129
Score = 75.9 bits (185), Expect = 2e-13
Identities = 96/461 (20%), Positives = 167/461 (36%), Gaps = 57/461 (12%)
Query: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVK 229
+ P + P+P P K + +P+ + PAP TP+ P P +
Sbjct: 678 KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPT----TPKKPAPK-E 732
Query: 230 VKEPSVQEATSTS---DILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRS 286
+ + +E TST+ PK PKEP+P KE T P K +
Sbjct: 733 LAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTT----PKEPAPTTP------KGTA 782
Query: 287 RTRSRSPSHTRPRRRH-------RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR 339
T + P+ T P++ ++ + + +P+P TP P P+
Sbjct: 783 PTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842
Query: 340 RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
+P ++S + + K+P SP T LS +P +
Sbjct: 843 APTTP-----------ETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALEN 891
Query: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459
P P P KT + P+ + T K + + RT+ + T + APK K
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTT-TAKDKTTERDLRTTPETT-----------TAAPKMTK 939
Query: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
+ +E+ K+ A + + Q ++ ++ + PK + K
Sbjct: 940 ETATTTEKTTESKITATTT----QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 995
Query: 520 RRRHSPSRSASPSPR-KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR 578
+ P +A P R K T+P+ ++ PT ++ P P R+ +T TP PR
Sbjct: 996 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKK-PKTMPRVRKPKT-TPTPR 1053
Query: 579 RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
+ T + P +P+ R +Q P+ P + P
Sbjct: 1054 KMTSTMP--ELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNP 1092
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 138 bits (348), Expect = 2e-32
Identities = 149/752 (19%), Positives = 275/752 (36%), Gaps = 79/752 (10%)
Query: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
S+ + + S SP+ ++ +PR S P + + S + T + K+ +
Sbjct: 105 STTQHNKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 163
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
+ E + KE E TS D+ K P PK + K KE T
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----- 218
Query: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRR 340
T + P+ T P+ + +S P+ + P+P P P
Sbjct: 219 -------TTPKEPASTTPKEPTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTT 266
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSR-SPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
++ P + A + + ++++S + PK+P T P T P+ + P+
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP- 325
Query: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459
P+ P P P T+ P P T K +P + + K + P+P
Sbjct: 326 TPTTPKEPAPTTKE-PAPT----TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380
Query: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
+ E +A + ++ ++ ++ S +++++ P K
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP--KEPAPTT 438
Query: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
++ +P+ P+P KE +P ++ +P+ P + P+P P + T P++
Sbjct: 439 PKKPAPTTPKEPAPTT-PKEPAPTTTKKPAPTTP-----KEPAPTTP---KETAPTTPKK 489
Query: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPP--PKRRTASPPPPPKRRASPSPPPKRRVSH 637
TP+ P + +P + +P +P+ P P T P P +A+ PK
Sbjct: 490 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 549
Query: 638 SPP------PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
+P PK+ + K +P+ KG++P+ + P P P+P+ AP
Sbjct: 550 TPKEPAPTTPKEPAPTTPKETAPTTP----KGTAPTT----LKEPAPTTPKKPAPKELAP 601
Query: 692 QTSSSP---------PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742
T+ P P +G + + + +P+ P + P +K+ A +P+
Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 661
Query: 743 SVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
+ + + P PAP +P ++ +P+T PA K +PT +PP +
Sbjct: 662 KPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTT 720
Query: 803 DQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV-----AAAAAAAVTPAAIAAATTTL 857
+ K+ D+ + KA+ TPAA TT
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 780
Query: 858 AQ------------EEPVAAPEPKKETESEAE 877
A+ E AAP+ KET + E
Sbjct: 781 AKDKTTERDLRTTPETTTAAPKMTKETATTTE 812
Score = 113 bits (282), Expect = 9e-25
Identities = 151/755 (20%), Positives = 264/755 (34%), Gaps = 83/755 (10%)
Query: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT-PELPEPSVK 229
+P KS +P+ + +E + + P T ++ P+P K T P+ P P+
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTP 306
Query: 230 VKEPSVQEATSTSDILKVPKP----EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSR 285
K K P P EP P KEP+P KE T P K
Sbjct: 307 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP----TTPKEPAPTAP------KKP 356
Query: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPR--RRPSP---RRRPSPRRRTPPRRMPPPPRHRR 340
+ T + P+ T P+ + ++ SP + P+P + P+ + P P +
Sbjct: 357 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR 400
SP + + + + ++ + + PK+P T P T P+ + P+
Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476
Query: 401 PSPPATPP--PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR-ESPSP-APK 456
+P T P PK TP++ T + + + T + T E P+P PK
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536
Query: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE----RPKRSHV 512
+ K A + ++ + ++ G++ ++ E PK+
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596
Query: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572
K + + + P+P T+P+G +P P + P+P P T
Sbjct: 597 KELAPTTTKEPTSTTCDKPAP------TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650
Query: 573 PTPPPRRRTP-SPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP 631
P TP P P+ +P+ + P P+P + TA P +P P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 709
Query: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
PP S T + P+ K SP ST E + K SP+
Sbjct: 710 PTTPETPPPTTSEVSTPTTTKEPTTIHK-----SPDESTPELSAEPTPKALENSPKEPGV 764
Query: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE-----PKKIKKAASPSPQSVR- 745
T+ +P A++ P+ + T R + TPE PK K+ A+ + ++
Sbjct: 765 PTTKTP------AATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKETATTTEKTTES 817
Query: 746 --------------------RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
++++ ++ + +P+ K + + ++ P P
Sbjct: 818 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK-PEETAKPKDR 876
Query: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845
+K+ TP P P + + K KK K + +K K +K +
Sbjct: 877 ATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 932
Query: 846 TPAAIAAATTTLAQEEP---VAAPEPKKETESEAE 877
A TTT + P + PK E AE
Sbjct: 933 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 967
Score = 35.0 bits (79), Expect = 0.32
Identities = 20/81 (24%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 165 KRERSRSPRRR----KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
K E + P+ R K+ +P P++ P + +K + ++ P+ + R P P ++ T
Sbjct: 866 KPEETAKPKDRATNSKATTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 922
Query: 221 PELPE--PSVKVKEPSVQEAT 239
+PE P+ ++ E +Q T
Sbjct: 923 STMPELNPTSRIAEAMLQTTT 943
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 138 bits (348), Expect = 2e-32
Identities = 149/752 (19%), Positives = 275/752 (36%), Gaps = 79/752 (10%)
Query: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
S+ + + S SP+ ++ +PR S P + + S + T + K+ +
Sbjct: 146 STTQHNKVSTSPKITTAKPINPRP-SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTS 204
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
+ E + KE E TS D+ K P PK + K KE T
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTP----- 259
Query: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRR 340
T + P+ T P+ + +S P+ + P+P P P
Sbjct: 260 -------TTPKEPASTTPKEPTPTTIKS-----APTTPKEPAPTTTKSAPTTPKEPAPTT 307
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSR-SPPKKPPKRTSSPPRKTRRLSPSASPPRRRH 399
++ P + A + + ++++S + PK+P T P T P+ + P+
Sbjct: 308 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP- 366
Query: 400 RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459
P+ P P P T+ P P T K +P + + K + P+P
Sbjct: 367 TPTTPKEPAPTTKE-PAPT----TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421
Query: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
+ E +A + ++ ++ ++ S +++++ P K
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP--KEPAPTT 479
Query: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
++ +P+ P+P KE +P ++ +P+ P + P+P P + T P++
Sbjct: 480 PKKPAPTTPKEPAPTT-PKEPAPTTTKKPAPTTP-----KEPAPTTP---KETAPTTPKK 530
Query: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPP--PKRRTASPPPPPKRRASPSPPPKRRVSH 637
TP+ P + +P + +P +P+ P P T P P +A+ PK
Sbjct: 531 LTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT 590
Query: 638 SPP------PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
+P PK+ + K +P+ KG++P+ + P P P+P+ AP
Sbjct: 591 TPKEPAPTTPKEPAPTTPKETAPTTP----KGTAPTT----LKEPAPTTPKKPAPKELAP 642
Query: 692 QTSSSP---------PPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742
T+ P P +G + + + +P+ P + P +K+ A +P+
Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK 702
Query: 743 SVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
+ + + P PAP +P ++ +P+T PA K +PT +PP +
Sbjct: 703 KPAPKELAPTTTKGPTSTTSDKPAPTTPKET-APTTPKEPAPTTPKKPAPTTPETPPPTT 761
Query: 803 DQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV-----AAAAAAAVTPAAIAAATTTL 857
+ K+ D+ + KA+ TPAA TT
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTT 821
Query: 858 AQ------------EEPVAAPEPKKETESEAE 877
A+ E AAP+ KET + E
Sbjct: 822 AKDKTTERDLRTTPETTTAAPKMTKETATTTE 853
Score = 113 bits (282), Expect = 9e-25
Identities = 151/755 (20%), Positives = 264/755 (34%), Gaps = 83/755 (10%)
Query: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT-PELPEPSVK 229
+P KS +P+ + +E + + P T ++ P+P K T P+ P P+
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-TKEPAPTTTKSAPTTPKEPAPTTP 347
Query: 230 VKEPSVQEATSTSDILKVPKP----EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSR 285
K K P P EP P KEP+P KE T P K
Sbjct: 348 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP----TTPKEPAPTAP------KKP 397
Query: 286 SRTRSRSPSHTRPRRRHRSRSRSYSPR--RRPSP---RRRPSPRRRTPPRRMPPPPRHRR 340
+ T + P+ T P+ + ++ SP + P+P + P+ + P P +
Sbjct: 398 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR 400
SP + + + + ++ + + PK+P T P T P+ + P+
Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517
Query: 401 PSPPATPP--PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR-ESPSP-APK 456
+P T P PK TP++ T + + + T + T E P+P PK
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577
Query: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE----RPKRSHV 512
+ K A + ++ + ++ G++ ++ E PK+
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637
Query: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRT 572
K + + + P+P T+P+G +P P + P+P P T
Sbjct: 638 KELAPTTTKEPTSTTCDKPAP------TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691
Query: 573 PTPPPRRRTP-SPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP 631
P TP P P+ +P+ + P P+P + TA P +P P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTK-GPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA 750
Query: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAP 691
PP S T + P+ K SP ST E + K SP+
Sbjct: 751 PTTPETPPPTTSEVSTPTTTKEPTTIHK-----SPDESTPELSAEPTPKALENSPKEPGV 805
Query: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE-----PKKIKKAASPSPQSVR- 745
T+ +P A++ P+ + T R + TPE PK K+ A+ + ++
Sbjct: 806 PTTKTP------AATKPEMTTTAKDKTTE-RDLRTTPETTTAAPKMTKETATTTEKTTES 858
Query: 746 --------------------RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
++++ ++ + +P+ K + + ++ P P
Sbjct: 859 KITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK-PEETAKPKDR 917
Query: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845
+K+ TP P P + + K KK K + +K K +K +
Sbjct: 918 ATNSKATTPKPQKPTKAPK----KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTS 973
Query: 846 TPAAIAAATTTLAQEEP---VAAPEPKKETESEAE 877
A TTT + P + PK E AE
Sbjct: 974 RIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAE 1008
Score = 35.0 bits (79), Expect = 0.32
Identities = 20/81 (24%), Positives = 40/81 (49%), Gaps = 9/81 (11%)
Query: 165 KRERSRSPRRR----KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
K E + P+ R K+ +P P++ P + +K + ++ P+ + R P P ++ T
Sbjct: 907 KPEETAKPKDRATNSKATTPKPQK---PTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMT 963
Query: 221 PELPE--PSVKVKEPSVQEAT 239
+PE P+ ++ E +Q T
Sbjct: 964 STMPELNPTSRIAEAMLQTTT 984
>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
Length = 653
Score = 134 bits (336), Expect = 5e-31
Identities = 149/521 (28%), Positives = 200/521 (38%), Gaps = 80/521 (15%)
Query: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
PPP+ ++ + RR R L S SSS R K+ S + R S S S
Sbjct: 166 PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLR-------KKKKSVKKHRRDRSDSGS 218
Query: 394 PPRRRHRP-SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
+RRHR S K + P + R+S S S ++ H + SPS
Sbjct: 219 RRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHYSDSR--SPS 276
Query: 453 PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
LS D+G K + R +S S SG S +R S
Sbjct: 277 --------RLSPKHRDEGRKTGSQ---------RSSGSRSPSPSGGSGWGSPQRNGGSGQ 319
Query: 513 KNGEVGRR--RRHSP-SRSASPSPRKRQKETS----PRGRRRRSPSP---PPTRRRRSPS 562
++G G R HSP + +SPSPR R K + P R + SPSP P ++ R +
Sbjct: 320 RSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRGGRA 379
Query: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP------IQRRYSPSPPPKRRTAS 616
RRRR R R+ + PRRR R +PP + R S S R A
Sbjct: 380 AGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAP 439
Query: 617 PPPPPK----------RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666
P P +RA PP R S SP P +R P S R
Sbjct: 440 GPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG----RRGGPEGKSSSRSPGPH 495
Query: 667 SRSTREARSPQPNKRHSPSPRPRAPQTSSSPP-PVRRGASSSPQRRQSPSPSTRPIRRVS 725
RS +RSP ++ S RP +P S SP P+ R + R S + +TR RR S
Sbjct: 496 PRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRR-S 554
Query: 726 RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785
R+ P + ++ SPS RR++S+R P P + P+ S S ST P
Sbjct: 555 RSYSPIRKRRRDSPSFMEPRRITSARK---RPIPYYRPSPSSSSSCLSSDYSTRSHSRSP 611
Query: 786 V----------------KKAKSP--TPSPSPPRNSDQEGGG 808
+ +SP TPSPS S E GG
Sbjct: 612 SPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652
Score = 128 bits (322), Expect = 2e-29
Identities = 175/630 (27%), Positives = 249/630 (39%), Gaps = 101/630 (16%)
Query: 124 LELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER------SRSPRRRKS 177
+ELK E+++ EQ +Q ++ EKE + +R + +PR +
Sbjct: 63 VELKCMELQEMMEEQGYSEEEIRQKVGTFRQMLMEKEGVLTREDRPGGHIVAETPRLTEG 122
Query: 178 RSPSPRRR-----SSPVRRERKRSHSRSPR-HRTK---SRSPSPAPEKKEKTPELPEPSV 228
P PV + S R R +RTK S S SP P+KK+K S
Sbjct: 123 AEPGLEYAPFDDDDGPVDCDCPASCYRGHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSR 182
Query: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-------------PEKNSKKEKEKEKTR 275
K + + + +S L+ K ++ S K +KEK KEK R
Sbjct: 183 KKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKR 242
Query: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS---YSPRRRPSPRRRPSPRRRTPPRRM 332
P + S + RS S SH+ H S SRS SP+ R R+ S +R+ R
Sbjct: 243 PHTESPGR-RSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGS--QRSSGSRS 299
Query: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
P P SP +R S SG+ S + SPP KP SSP + R + +A
Sbjct: 300 PSPSGGSGWGSP--QRNGGSGQRSGAHGGRPGS-AHSPPDKP----SSPSPRVRDKAAAA 352
Query: 393 S---PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449
+ P R + PSP + P + R + R R+ R R+S + +G R
Sbjct: 353 APTPPARGKESPSPRSAPSSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRG---RR 409
Query: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPK- 508
P PAP PR S S +SSSDSGS + P+
Sbjct: 410 RPRPAP-PRGSSRSLS-----------------------RARSSSDSGSGRGAPGPGPEP 445
Query: 509 RSHVKNGEVGRRRRHSPSR----SASPSPRKRQKETSPRGR-RRRSPSPPPTRRRRSPSP 563
S +G G+R + P R S SPSP + P G+ RSP P P RS S
Sbjct: 446 GSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHP----RSWSS 501
Query: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS---PPPP 620
+ P + R+ + R +PS P + P R + R+S + + R S P
Sbjct: 502 SRSPSKSRSRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIR 561
Query: 621 PKRRASPSPPPKRRVSHS---PPPKQRSSPVTK-------------RRSPSLSSKHRKGS 664
+RR SPS RR++ + P P R SP + RSPS H S
Sbjct: 562 KRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSRSPSPGHSHGSYS 621
Query: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTS 694
S S TR +R+ P++ SPS R+ S
Sbjct: 622 SRSHGTR-SRTRSPSRTPSPSYHSRSSSES 650
Score = 124 bits (311), Expect = 4e-28
Identities = 146/523 (27%), Positives = 204/523 (39%), Gaps = 96/523 (18%)
Query: 250 PEPIPEPKEPSPEKNSKKEKEKEK------TRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
P P + K+ + S+K++ E + P + + + R RS S +R R+ R
Sbjct: 166 PPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRSDSGSR--RKRR 223
Query: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
RSRS +R+ + + P +P R R R SS S S SS
Sbjct: 224 HRSRSSKCKRKEKNKEKKRPHTESPGR---------------RSHRHSSGSSHSPSLSSH 268
Query: 364 SSRSRSPPKKPPK-----RTSSPPRKTRRLSPSAS------PPRRR-----------HRP 401
S SRSP + PK R + R + SPS S P+R RP
Sbjct: 269 YSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRP 328
Query: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461
+PP K SP+P R R + +P + +ESPSP P
Sbjct: 329 GSAHSPPDKP-SSPSP----RVRDKAAAAAPTPPA---------RGKESPSPRSAP---- 370
Query: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
S + +GG+ A ++RR+ RR+ +SS+ + RP + + R R
Sbjct: 371 ---SSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRAR 427
Query: 522 RHSPSRSASPSPRKRQKETSPR---GRRRRSPSPPPTRRRRSPSPAPPPR-RRRTPTPPP 577
S S S +P + S R G +R+ PP R S SP+P RR P
Sbjct: 428 SSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKS 487
Query: 578 RRRTPSPPPR----RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR 633
R+P P PR RSPS R +R +SPS R+ SP P R +
Sbjct: 488 SSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPS-----RSPSPKKPLSRDKDGEGRARH 542
Query: 634 RVSHSPPPKQRS---SPVTKRR--SPSLSSKHRKGS-----------SPSRSTREARSPQ 677
+ + ++RS SP+ KRR SPS R S SPS S+ S
Sbjct: 543 SEAEATRARRRSRSYSPIRKRRRDSPSFMEPRRITSARKRPIPYYRPSPSSSSSCLSSDY 602
Query: 678 PNKRHSPSPRPRAPQTS-SSPPPVRRGASSSPQRRQSPSPSTR 719
+ HS SP P S SS R + SP R SPS +R
Sbjct: 603 STRSHSRSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSR 645
Score = 108 bits (270), Expect = 2e-23
Identities = 128/491 (26%), Positives = 178/491 (36%), Gaps = 52/491 (10%)
Query: 118 GIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKS 177
G S + KK K R+ + + K++ + + K ++++ +KR + SP RR
Sbjct: 194 GSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSH 253
Query: 178 R--SPSPRRRSSPVRRERKRSHSR-SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
R S S S RS SR SP+HR + R ++P P P
Sbjct: 254 RHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPS-PSGGSGWGSPQ 312
Query: 235 VQEATSTSDILKVPKP----EPIPEPKEPSPEKNSK--------KEKEKEKTRPRSRSRS 282
+ +P P +P PSP K + KE PRS S
Sbjct: 313 RNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAPSS 372
Query: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
+ R + R RRR R RSRS + R RRRP P PP
Sbjct: 373 QGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRP---APP------------- 416
Query: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
R SS SLS + SSS S R P P+ S PPR R +
Sbjct: 417 ------RGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPAST 470
Query: 403 PPATPPPKTRHSPTPQQSNRTRKSRV-SVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE 461
P+ R P + S+R+ S S R+ K ++ SPS +P P+K
Sbjct: 471 SPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPL 530
Query: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
+ + + + + A++ + RR+ R + S S E R R+
Sbjct: 531 SRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFMEPRR---------ITSARK 581
Query: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
R P SPS +S R S SP P S S R RT +P RT
Sbjct: 582 RPIPYYRPSPS-SSSSCLSSDYSTRSHSRSPSPGHSHGSYSSRSHGTRSRTRSP---SRT 637
Query: 582 PSPPPRRRSPS 592
PSP RS S
Sbjct: 638 PSPSYHSRSSS 648
Score = 103 bits (258), Expect = 6e-22
Identities = 123/516 (23%), Positives = 191/516 (37%), Gaps = 84/516 (16%)
Query: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRV-------SVSPGRTSGKVTKHKGTEKR 448
R +H S A+PPPK + +K R+ S SP R K K ++
Sbjct: 155 RTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKHRRDRS 214
Query: 449 ESPSPAPK---PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
+S S + R + E++K K +S RR +R + S S S SS S+
Sbjct: 215 DSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTES-PGRRSHRHSSGSSHSPSLSSHYSDSR 273
Query: 506 RPKRSHVKNGEVGRR---RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS 562
P R K+ + GR+ +R S SRS SPS G SP +RS +
Sbjct: 274 SPSRLSPKHRDEGRKTGSQRSSGSRSPSPSG----------GSGWGSPQRNGGSGQRSGA 323
Query: 563 PAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
P SPP + SPSPR + + A+ P P
Sbjct: 324 HGGRPGSAH-----------SPPDKPSSPSPR---------------VRDKAAAAAPTPP 357
Query: 623 RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682
R SP P+ S + + +RR + R+ SRS+ A P +R
Sbjct: 358 ARGKESPSPRSAPSSQGRGGRAAGGAGRRR------RRRRRRRRSRSSASA----PRRRG 407
Query: 683 SPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP----------IRRVSRTPEPKK 732
PRP P+ SS R +S S R +P P P R R P +
Sbjct: 408 RRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARP 467
Query: 733 IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSP 792
+ SP R +S S SP P + + SP +S+S S P P ++SP
Sbjct: 468 ASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSP---SRSP 524
Query: 793 TPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
+P R+ D EG + + + + ++ + + +K +++ +P+ +
Sbjct: 525 SPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRD-----------SPSFMEP 573
Query: 853 ATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLR 888
T A++ P+ P + S + H R
Sbjct: 574 RRITSARKRPIPYYRPSPSSSSSCLSSDYSTRSHSR 609
Score = 86.7 bits (213), Expect = 9e-17
Identities = 107/399 (26%), Positives = 143/399 (35%), Gaps = 103/399 (25%)
Query: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGR-------------------RRRSPSPPPT 555
G G R +H S SASP P+K++K+ R R++ S
Sbjct: 150 GHRGYRTKHWSSSSASPPPKKKKKKKGGHRRSRKKRRLESECSCGSSSPLRKKKKSVKKH 209
Query: 556 RRRRSPSPAPPPRRRRTPTPPPRRR----------TPSPPPR-RRSPSPRRYSPPIQRRY 604
RR RS S + RR R+ + +R+ T SP R R S +SP + Y
Sbjct: 210 RRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHTESPGRRSHRHSSGSSHSPSLSSHY 269
Query: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS------S 658
S S P R + PK R QRSS RSPS S S
Sbjct: 270 SDSRSPSRLS----------------PKHRDEGRKTGSQRSS---GSRSPSPSGGSGWGS 310
Query: 659 KHRKGSSPSRSTREARSP-----QPNKRHSPSPRPRAPQTSSSP-PPVRRGASSSP---- 708
R G S RS P P+K SPSPR R +++P PP R S SP
Sbjct: 311 PQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPRSAP 370
Query: 709 ---------------------QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRV 747
+RR+S S ++ P RR R P P + +S S R
Sbjct: 371 SSQGRGGRAAGGAGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAP-PRGSSRSLSRARSS 429
Query: 748 SSSRSVSGSPEP----------------AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
S S S G+P P A ++PP S SP + P K+ S
Sbjct: 430 SDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSS 489
Query: 792 PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKK 830
+P P P S K + + +K+ + KK
Sbjct: 490 RSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKK 528
>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
Length = 953
Score = 134 bits (336), Expect = 5e-31
Identities = 130/521 (24%), Positives = 202/521 (38%), Gaps = 77/521 (14%)
Query: 138 QEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSH 197
+E+ ++++ +++ + E++ RE+R+R R R R +RR RER +
Sbjct: 402 RERERERERENRQRERERERERDRERERRQREREREREHERDKERQRRKEEWERERAKRD 461
Query: 198 SRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK 257
+ +HR + R EK + P P+P + EP +EA +T +K P +
Sbjct: 462 EKDRQHRDRDREKEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRR 521
Query: 258 EPSPEK------NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT-RPRRRHRSRSRSYS 310
SP+K + + + + KT S S S S SR+ SRS S++ R RSRS SYS
Sbjct: 522 SKSPKKKLGVSVSPSRARRRRKTSASSASASNS-SRSSSRSSSYSGSGSSRSRSRSSSYS 580
Query: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
S R R+ R P S SP R S G +
Sbjct: 581 SYSSRSSRHSSFSGSRSRSRSFSSSP----SPSPTPSPHRPSIRTKGEPAPPPGKAGEKS 636
Query: 371 PKKPPKRTSSPPRKTRRLSPSASP-----PRRRHRPSPPATPPPKTR------------H 413
KKP +PP+ T+ +P P PR R PA PP+ R +
Sbjct: 637 VKKPAP-PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSY 695
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKH------------KGTEKRESPSPAPKPRKVE 461
S + +S S VS TS + H S SPAP + E
Sbjct: 696 SGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKE 755
Query: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV--------- 512
+S+++ G K + ++R + + + +G SS + P+++
Sbjct: 756 KGKSKKEDGVK----EEKRKRDSSTQPPKSAKPPAGGKSSQQPSTPQQAPPGQPQQGTFV 811
Query: 513 -----------KNGEVGRRRRHSPSRS--ASPSPRKRQKETSPRGRRRR-------SPSP 552
K + G R+R+ PS SP P KR + RG R R SP P
Sbjct: 812 AHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPPPAKRPNTSPDRGSRDRKSGGRLGSPKP 871
Query: 553 PPTRRRRSPSPAPPPRRRRTPTPPPR--RRTPSPPPRRRSP 591
R + S +PA P R+R +P + + S P + P
Sbjct: 872 ERQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDP 912
Score = 110 bits (275), Expect = 6e-24
Identities = 142/616 (23%), Positives = 210/616 (34%), Gaps = 119/616 (19%)
Query: 273 KTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
+T P R + R R R + R R R R R R R+R R R R + RR
Sbjct: 394 ETEPYHNYRERERERERE---NRQRERERERERDRERERRQREREREREHERDKERQRRK 450
Query: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
R R R R+ R + RSP +PP R + PP+K
Sbjct: 451 EEWERERAKRDEKDRQHRDRDREKEREKEKGKPKPRSP--QPPSRQAEPPKKEA------ 502
Query: 393 SPPRRRHRPSPPATPPPKTRHSPT---PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449
AT P+ + + P + +++ K ++ VS
Sbjct: 503 ------------ATTGPQVKRADEWKDPWRRSKSPKKKLGVSV----------------- 533
Query: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509
SPS A + RK S + + ++ S Y S SS SS R R
Sbjct: 534 SPSRARRRRKTSASSASASNSSRSSSRSS-----SYSGSGSSRSRSRSSSYSSYSSRSSR 588
Query: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR----RSPSPAP 565
+G R R S S S SP+P + P R + P+PPP + + P+P P
Sbjct: 589 HSSFSGSRSRSRSFSSSPSPSPTPSPHR----PSIRTKGEPAPPPGKAGEKSVKKPAPPP 644
Query: 566 -PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624
PP+ +T P P P P R +PP +R S S + S R
Sbjct: 645 APPQATKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGSGSGSGSSYSGSSSRSRS 704
Query: 625 ASPS----------------------------PPPKRRVSHSPPPKQ-RSSPVTKRRSPS 655
S S P S SP P Q R ++
Sbjct: 705 LSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDG 764
Query: 656 LSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP---------------V 700
+ + RK S ++ + A+ P K S +P PQ + P +
Sbjct: 765 VKEEKRKRDSSTQPPKSAKPPAGGK---SSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLL 821
Query: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
+ A ++R PS R ++P P K + SP S R S R GSP+P
Sbjct: 822 NKAADKGSRKRYEPSDKDR------QSPPPAK-RPNTSPDRGSRDRKSGGR--LGSPKPE 872
Query: 761 ------AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKK 814
+K P AP + SP + S V K+ P + ++ ++++
Sbjct: 873 RQRGQNSKAPAAPADRKRQLSPQSKSSSKVTSVPGKASDPGAASTKSGKASTLSRREELL 932
Query: 815 KDKKHKKDKKHKKHKK 830
K K +D +K K
Sbjct: 933 KQLKAVEDAIARKRAK 948
Score = 95.5 bits (236), Expect = 2e-19
Identities = 106/407 (26%), Positives = 161/407 (39%), Gaps = 45/407 (11%)
Query: 459 KVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG 518
+V+ +E+E + + ++ RQ R+ ++ E ER +R H ++ E
Sbjct: 389 RVQYTETEPYHNYRERERERERENRQRERERERERDRERERRQRERER-EREHERDKERQ 447
Query: 519 RRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP----APPPRRRRTPT 574
RR+ A + RQ R + R P + RSP P A PP++ T
Sbjct: 448 RRKEEWERERAKRDEKDRQHRDRDREKEREKEKGKP--KPRSPQPPSRQAEPPKKEAATT 505
Query: 575 PPPRRRTPS-PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR 633
P +R P RRS SP++ + SPS +RR S +S S
Sbjct: 506 GPQVKRADEWKDPWRRSKSPKK---KLGVSVSPSRARRRRKTSASSASASNSSRSSSRSS 562
Query: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS-SPSRSTREARSPQPNKRHSPSPRPRAPQ 692
S S + RS + S SS+H S S SRS + SP P SP+P P P
Sbjct: 563 SYSGSGSSRSRSRSSSYSSYSSRSSRHSSFSGSRSRSRSFSSSPSP----SPTPSPHRPS 618
Query: 693 TSS----SPPPVRRGASSSPQRRQSPSP-----STRPI---------------RRVSRTP 728
+ +PPP + G S + P+P +T P+ R +RTP
Sbjct: 619 IRTKGEPAPPPGKAGEKSVKKPAPPPAPPQATKTTAPVPEPTKPGDPREARRKERPARTP 678
Query: 729 EPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTN---WSPAVP 785
++ + S SSSRS S S + A S + S + A P
Sbjct: 679 PRRRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASP 738
Query: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHK 832
V A S +P+P+ R ++G KK+ K++K K+D + K K
Sbjct: 739 VSSASSRSPAPAQTRK--EKGKSKKEDGVKEEKRKRDSSTQPPKSAK 783
Score = 92.4 bits (228), Expect = 2e-18
Identities = 174/824 (21%), Positives = 286/824 (34%), Gaps = 138/824 (16%)
Query: 131 IKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
++ +E E+ A+ E++D EE +S K + S SR P+ SSP
Sbjct: 43 VRASDLEDEESAARGPSQEEEDNHSDEEDRASEPKSQDQDSEVNELSRGPT----SSPCE 98
Query: 191 RERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKP 250
E + R+ E T EL E + E +VP+
Sbjct: 99 EEGDEGE--------EDRTSDLRDEASSVTRELDEHELDYDE-------------EVPE- 136
Query: 251 EPIPEPKEPSPEK-NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR-- 307
EP P +E EK ++ ++EK + PR ++ +S S + +++
Sbjct: 137 EPAPAVQEDEAEKAGAEDDEEKGEGTPREEGKAGVQSVGEKESLEAAKEKKKEDDDGEID 196
Query: 308 ---------SYSPRRRPSPRR-RPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG 357
+ PS R+ RP P R + + R P
Sbjct: 197 DGEIDDDDLEEGEVKDPSDRKVRPRPTCRFFMKGNCTWGMNCRFIHP-----------GV 245
Query: 358 SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKT------ 411
+ + S +++ P P P +P P P PP PP ++
Sbjct: 246 NDKGNYSLITKADPFPPNGAPPLGPHPLMPANPWGGPVVDEILPPPPPEPPTESAWERGL 305
Query: 412 RHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP----------SPAPKPRKVE 461
RH+ + RK + P + T G ++RE S P+ +
Sbjct: 306 RHAKEVLKKATIRKEQ---EPDFEEKRFTVTIGEDEREFDKENEVFRDWNSRIPRDVRDT 362
Query: 462 LSESEED-----------KGGKM----AAADSVQQRRQYR-RQNQQSSSDSGSSSSSEDE 505
+ E D +GG+ + YR R+ ++ + E E
Sbjct: 363 VLEPYADPYYDYEIERFWRGGQYENFRVQYTETEPYHNYRERERERERENRQRERERERE 422
Query: 506 RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAP 565
R + + E R R H + R+R+KE R R +R R R
Sbjct: 423 RDRERERRQREREREREHERDKE-----RQRRKEEWERERAKRDEKDRQHRDRDRE---- 473
Query: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP--PIQRRYSPSPPPKRRTASPPPPPKR 623
+ R P+ R+P PP R+ P + + P +R P RR+ SP
Sbjct: 474 --KEREKEKGKPKPRSPQPPSRQAEPPKKEAATTGPQVKRADEWKDPWRRSKSPKKKLGV 531
Query: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK--R 681
SPS +RR + + +S + RS S S GSS SRS + S ++ R
Sbjct: 532 SVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGS---GSSRSRSRSSSYSSYSSRSSR 588
Query: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741
HS R+ R SSSP +PSP RP R P P K
Sbjct: 589 HSSFSGSRSRS---------RSFSSSPSPSPTPSPH-RPSIRTKGEPAPPPGK------- 631
Query: 742 QSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTN-WSPAVPVKKAKSPTPSPSPPR 800
+ +SV P P PPAPP ++ +P P P + + P+ +PPR
Sbjct: 632 ------AGEKSVK-KPAP----PPAPPQATKTTAPVPEPTKPGDPREARRKERPARTPPR 680
Query: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTP-----AAIAAATT 855
G G + + A +++++A A +A+ +
Sbjct: 681 RRTLSGSGSGSGSSYSGSSSRSRSLSVSSVSSVSSATSSSSSAHSVDSEDMYADLASPVS 740
Query: 856 TLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRKAQ 899
+ + P A K++ +S+ ED + + EK R+ + + + A+
Sbjct: 741 SASSRSPAPAQTRKEKGKSKKEDGVKE-EKRKRDSSTQPPKSAK 783
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 128 bits (321), Expect = 3e-29
Identities = 168/729 (23%), Positives = 254/729 (34%), Gaps = 113/729 (15%)
Query: 167 ERSRSPRRRKSRSPSPR--RRSSPVRR-------ERKRSHSRSPRHRTKSRSPSPAPEKK 217
+ R P ++ S P SSPV E S S + SP+P K
Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP---IPEPKEPSPEKNSKKEKEKEKT 274
TP P + T T ++ +P P+ P PK+ + +K +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARA 923
Query: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPR---RRPSPRRRPSPRRRTPPRR 331
P + S S + +P P SP+ PSP+ P+P TPP
Sbjct: 924 TPAPKGIPASPSPKGAPTPPAATPP----------SPKGGPATPSPKWAPTPPAATPPSP 973
Query: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP------------KRTS 379
P +P + G ++ S P PP K S
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033
Query: 380 SPPRKTR---RLSPSASP----------------------PRRRHRPSPPATPPPKTRHS 414
+PP T + SP+A+P P + P+PPA PP +
Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGG 1093
Query: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTK-HKG---TEKRESPSP-----APKPRKVELSES 465
P + P G T HKG T PSP P P+ + +
Sbjct: 1094 PATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1153
Query: 466 EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV-----KNGEVGRR 520
K A + S G ++ S P K G
Sbjct: 1154 ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213
Query: 521 RRHSPSRSAS--PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA-PPPRRRRTP---T 574
+ +P+ A+ PSP+ SP+G + PP+ + PA PPP+ TP T
Sbjct: 1214 PKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG---GPATPPPKGAPTPPAAT 1270
Query: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP-PPPPKRRASPSPPPKR 633
PP + + PP + +P+P +PP + + PPK P PP + SP PP +
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 634 RVSHSP---PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSP---QPNKRHSPSPR 687
P PP + +P +PS KG + S++E +P P+ + P+
Sbjct: 1331 GAPTPPAVTPPSPKGTPTLPATTPS-----SKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Query: 688 PRAPQTSSSPPPVRRGASSSPQRRQSP--SPSTRPIRRVSRTPE----------PKKIKK 735
P +P+ + P + +S SP +P+T R + TP P +KK
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
Query: 736 A-ASPSPQSVRRVSSSRSVSGSP---EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
A A+ +P+ SS+ P P+ K+PPAP S SP + P+
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 792 PTPSPSPPR 800
P PS P+
Sbjct: 1506 PAVIPSSPK 1514
Score = 102 bits (254), Expect = 2e-21
Identities = 187/835 (22%), Positives = 283/835 (33%), Gaps = 142/835 (17%)
Query: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
SS K+ R+ + SPSP+ +P + SP+ + SP AP T
Sbjct: 915 SSSPKKARATPAPKGIPASPSPKGAPTP-----PAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 221 PELPE-----PSVK-VKEPSVQEATSTSDILKVPKPEPIPEPKE---PSPE--------- 262
P P+ PS K P S P P+ P P PSP+
Sbjct: 970 PPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFP 1029
Query: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY------------S 310
K + P+ + + +P+ T P + + S S
Sbjct: 1030 KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 311 PR---RRPSPRRRPSPRRRTPPRR---MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
P+ PSP+ P P TPP + PP +P L+ +
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Query: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRH---RPSPPATPPPKTRHSPTPQQSN 421
+ + P P ++PP K +P+A+PP + PSP P P+P+
Sbjct: 1150 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1209
Query: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
T + + P + KG SP AP + KGG A +
Sbjct: 1210 ATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPT---TPAATPPSPKGGP---ATPPPK 1261
Query: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHV-----KNGEVGRRRRHSPSRSAS--PSPR 534
S G ++ P + V K G + +P+ A+ PSP+
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321
Query: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594
P+G PP+ + PA P + PT P + P+PP +PS +
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA--TPSHK 1379
Query: 595 ---RYSPPIQRRYSPSPPPKRRTASP---PPPPKRRASPSPPPKRRVSHSP------PPK 642
+PP +R P PK SP P PK+ +P+ P R + +P PP
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK--APATPVTREGAATPSKGDLTPPA 1437
Query: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRS---TREARSPQPNKRHSPSPRPRAPQTSSSPP- 698
+PV+ +++P+ S+ ++PS T A +P P+ + P+P+ A TSSSP
Sbjct: 1438 V--TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP-PSPKEPPAPKQVA--TSSSPKK 1492
Query: 699 ----PVRRGASS--------------SPQRRQSPSPSTRPI--RRVSRTPEPKKI----- 733
P GA + +P R+ P T + ++ T PK+
Sbjct: 1493 APATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
Query: 734 -------KKAASPSPQSVRRVSSSRSVSGSPE-----------------PAAKKPPAP-- 767
K A P+P+ SS+ S P P A P+P
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 768 -PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHK 826
P+P PS PA P K +P +P D K + K
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 827 KHKKHKKE-KAVAAAAAAAVTPAAIAAA-----TTTLAQEEPVAAPEPKKETESE 875
KK K V A A TP A T + P P+P + S+
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSK 1727
Score = 99.4 bits (246), Expect = 1e-20
Identities = 142/670 (21%), Positives = 228/670 (34%), Gaps = 99/670 (14%)
Query: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE-----PIP 254
SP+ + SP AP TP P+ + P + T+ P P+ P P
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP---KGAPTTPAATPPSPKGGPATPPP 1260
Query: 255 EPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS-RSPSHTRPRRRHRSRSRSYSPRR 313
+ P K T P + + + S + T P + + + P
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSP 1320
Query: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK 373
+ SP P TPP PP P+ + ++ S G ++ SS +PP
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA------TTPSSKGGPTTPSSKEGPTPPAA 1374
Query: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP----------TPQQSNRT 423
P P + P + P+ PA P + +P TP + + T
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434
Query: 424 RKSRVSVS-------------PGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
+ VS P S K SP P P++V S S +
Sbjct: 1435 PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP 1494
Query: 471 GKMA-------------AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517
A + V RR ++ S + PK + +
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI----- 1549
Query: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTP-- 575
P PSP+K +P+ +P+ P ++ SP P + P+P
Sbjct: 1550 -------PPAMTVPSPKKTPAIPTPK----EAPATPSSKEASSPPAVTPSTYKGAPSPKE 1598
Query: 576 ---PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR-RASPSPPP 631
PP +PSP + +P+P +PP + +P PK SPP P + SP+ P
Sbjct: 1599 LLIPPAVTSPSP---KEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655
Query: 632 KRRVSHSPPPKQRSSPVTKRRSPSLSSK----HRKGSSPSRSTREARSPQPNKRHSPSPR 687
Q S + ++ P+ + S+P + + PQ K + SP
Sbjct: 1656 SVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP 1715
Query: 688 ----PRAPQTSSSPP---------PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIK 734
P A S P PV++ +S + + + + P+ PE K
Sbjct: 1716 ICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLA----PPESKAST 1771
Query: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP 794
+ + + V S SVS +P P P AP SPV + P + P+ P +SP+
Sbjct: 1772 PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP-SPVPTLPPKQQFLPSSPGLVLESPS- 1829
Query: 795 SPSPPRNSDQ 804
P P + D+
Sbjct: 1830 KPLAPADEDE 1839
Score = 90.9 bits (224), Expect = 5e-18
Identities = 110/473 (23%), Positives = 176/473 (37%), Gaps = 83/473 (17%)
Query: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS-PPATPPPKTR------HSPTPQQ 419
S + P P + + P T L+P P+ PS PPA PP T+ H+
Sbjct: 705 SENCPVAPSPQNTCAPLATLVLAPEI--PKSVPSPSLPPAGTPPGTKKVDGISHTSALAP 762
Query: 420 SNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSV 479
+ K + G ++ +K T +SPSP + + S
Sbjct: 763 VASSPKECPTEDSGASATASSKGTLTYLADSPSP-------------------LGVSVSP 803
Query: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG-RRRRHSPSRSASPSPRKRQK 538
Q +R ++ + SS + S + + + + SP+ + SP+P
Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP----- 858
Query: 539 ETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT----PPPRRRTPSPPPRRRSPSPR 594
SP+G +P+P PP+ TP+ P P+ +P P++
Sbjct: 859 -PSPKG----APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSM 913
Query: 595 RYSPPIQRRYSPSP-----------PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ 643
S P + R +P+P P A+PP P A+PSP + PP
Sbjct: 914 TSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP 973
Query: 644 RSSPVTKR-----RSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
+ P T P+ + KG + S + A +P P+ P +P+ S +
Sbjct: 974 KGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP-------PAVTPPSPKGSPAAT 1026
Query: 699 PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758
P +GA S+P PSP P + TP PK + + S + ++ S+ G+P
Sbjct: 1027 PFPKGA-STPPAATPPSPKGSP----AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT 1081
Query: 759 PAAKKPPAP------------PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
P A PP+P P P + PS A P K TP+ +PP
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPP 1134
Score = 69.3 bits (168), Expect = 2e-11
Identities = 124/570 (21%), Positives = 190/570 (33%), Gaps = 79/570 (13%)
Query: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP-IPEPKEPSPEKNS 265
+R + P K + TP P V +K+ A K +P +P PSP
Sbjct: 1421 TREGAATPSKGDLTPPAVTP-VSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSP---- 1475
Query: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP---- 321
KE P+ + S S + + P S PS RR P
Sbjct: 1476 -----KEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530
Query: 322 -------SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
+P P + PP P ++ + + + ++ SS + SPP
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAM----TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT 1586
Query: 375 PKR-TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG 433
P +P K + P+ + P + P+PPA PP P T
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGT---------- 1636
Query: 434 RTSGKVTKHKGTEKRESP-SPAPKPRKVELSESEEDKG----------GKMAAADSVQQR 482
TS VT + ++SP SPA K+ + + KG ++ A + +
Sbjct: 1637 PTSPPVTP---SSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPEST 1693
Query: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542
++ SS++S P S KNG G P + +P+P ++ S
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPS-AKNGSKG------PLSTVAPAPLLPVQKDSS 1746
Query: 543 RGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR 602
+ + + S P + P APP + TP P P S S SPP+
Sbjct: 1747 KTAKGKDASHSP----KGPL-APPESKASTPLTAAAFEKVLPKPESASVSAAP-SPPVSL 1800
Query: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662
+PSP P PPK++ PS P + P K + P + +
Sbjct: 1801 PLAPSPVPTL-------PPKQQFLPSSP---GLVLESPSKPLAPADEDELLPLIPPEPIS 1850
Query: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 722
G P +S P P P P P A Q P S + P
Sbjct: 1851 GGVPFQSVL-VNMPTPKSAGIPVPTPSAKQ----PVTKNNKGSGTESDSDESVPELEEQD 1905
Query: 723 RVSRTPEPKKIKKAASPSPQSVRRVSSSRS 752
T + ++ AA + V + SRS
Sbjct: 1906 STQATTQQAQLAAAAEIDEEPVSKAKQSRS 1935
Score = 68.2 bits (165), Expect = 3e-11
Identities = 114/472 (24%), Positives = 164/472 (34%), Gaps = 53/472 (11%)
Query: 353 ASLSGS--SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
ASL G+ S + + ++ P P ++P S S+SP SP AT K
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPL---SPEATLAKK 593
Query: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS------E 464
+ P P + S S +S V K +S P K + + E
Sbjct: 594 SLGEPLP--IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE 651
Query: 465 SEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHS 524
S + G A + +++ S + PK VK G +
Sbjct: 652 SADPAGVAPTTAKGT---------STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVP 702
Query: 525 PSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR---- 580
+ P Q +P +P P + PSP+ PP TPP ++
Sbjct: 703 TASENCPVAPSPQNTCAPLATLVLAPEIP----KSVPSPSLPP----AGTPPGTKKVDGI 754
Query: 581 --TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP--PPKRRVS 636
T + P SP + S A P P SP PP ++ S
Sbjct: 755 SHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGS 814
Query: 637 HSP--PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694
P P SSPV+ + L S SP P PSP+ AP S
Sbjct: 815 AGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP-----PSPKG-APTPS 868
Query: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVS-RTPEPKKIKKAA--SPSPQSVRRVSSSR 751
+ P +G + P+ +PS P + TP PK+ + S SP+ R + +
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPK 928
Query: 752 SVSGSPEP-AAKKPPA--PPSPVQS-QSPSTNWSPAVPVKKAKSPTPSPSPP 799
+ SP P A PPA PPSP +PS W+P P SP P+ P
Sbjct: 929 GIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATP 980
>gi|133922600 splicing factor, arginine/serine-rich 16 [Homo
sapiens]
Length = 674
Score = 125 bits (315), Expect = 1e-28
Identities = 143/495 (28%), Positives = 199/495 (40%), Gaps = 65/495 (13%)
Query: 119 IPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKD-----KRDKEEKE------------- 160
IP +E+ +E+ Q Q+ + D D ++DKEE E
Sbjct: 201 IPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKA 260
Query: 161 ------SSREKRE-RSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
S R++RE R + R RK PS RR SP KRS S S ++SRS SP
Sbjct: 261 MYSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE-SRSRSRSPT 319
Query: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN------SKK 267
P ++EK + +E + A + + + KP P+P P+P +N S
Sbjct: 320 PGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSS 379
Query: 268 EKEKEKTRPRSRSRSKSRSRTRS-RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
S SRS SRS +RS R + R R RSRSRS+S R S R S R
Sbjct: 380 SSSSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRG 439
Query: 327 TPPRRMPPPPRHRRSRSPVRR-----RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
HR SRSP RR RRRS S S S R R + +SS
Sbjct: 440 RRHSGGGSRDGHRYSRSPARRGGYGPRRRS------RSRSHSGDRYRRGGRGLRHHSSSR 493
Query: 382 PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTK 441
R + LSPS S R R HSP+P QS +SR S SP S +
Sbjct: 494 SRSSWSLSPSRSRSLTRSR-----------SHSPSPSQSRSRSRSR-SQSP---SPSPAR 538
Query: 442 HKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR-RQYRRQNQQSSSDSGSSS 500
K T SP+ K +K E + +E K + + R + N+Q +D ++
Sbjct: 539 EKLTRPAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQ 598
Query: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTR---- 556
++ + E+ R + ++R++ R+ RSPSP +R
Sbjct: 599 EKMIQQEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSS 658
Query: 557 -RRRSPSPAPPPRRR 570
RRRS S + P R
Sbjct: 659 SRRRSRSRSRSPHYR 673
Score = 80.9 bits (198), Expect = 5e-15
Identities = 132/550 (24%), Positives = 205/550 (37%), Gaps = 74/550 (13%)
Query: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271
P+ ++K+K E K+ S+ S + +V K PE +E + E+ S ++++
Sbjct: 148 PSEDEKKKLAE--------KKASIGYTYEDSTVAEVEKAAEKPEEEESAAEEESNSDEDE 199
Query: 272 ------------EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS----------- 308
E + + +K + R R+ + + +
Sbjct: 200 VIPDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEK 259
Query: 309 --YSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366
YS RR S R+R R + R PP + R SP + S S SSS S SR
Sbjct: 260 AMYSGRR--SRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPS---ESSSESRSR 314
Query: 367 SRSP-PKKPPKRTS----SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
SRSP P + K T + + +A+ PPA P P P P ++
Sbjct: 315 SRSPTPGREEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPG---GPAPGRNA 371
Query: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
R+ S S ++ + + + + + S S + + + + S +
Sbjct: 372 SARRRSSSSSSSSSASRTSSSRSSSRSSSRS---RRGGGYYRSGRHARSRSRSWSRSRSR 428
Query: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKR----- 536
R+Y R + SG S + R RS + G G RRR S SRS S +R
Sbjct: 429 SRRYSRSRSRGRRHSGGGSR-DGHRYSRSPARRGGYGPRRR-SRSRSHSGDRYRRGGRGL 486
Query: 537 QKETSPRGRRRRSPSPPPTR---RRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+ +S R R S SP +R R RS SP+P R R+ + R ++PSP P R +
Sbjct: 487 RHHSSSRSRSSWSLSPSRSRSLTRSRSHSPSPSQSRSRSRS---RSQSPSPSPAREKLTR 543
Query: 594 RRYSPPIQRRYSPSPPP--KRRTASPP---PPPKRRASPSPPPKRRVSHSPPPKQ----R 644
SP + + + P K A+ P P K + R+ Q +
Sbjct: 544 PAASPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQ 603
Query: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK---RHSPSPRPRAPQTSSSPPPVR 701
+ R L + RK R RE + + R S SP PR + SS
Sbjct: 604 QEHERQEREDELRAMARKIRMKERERREKEREEWERQYSRQSRSPSPRYSREYSSSRRRS 663
Query: 702 RGASSSPQRR 711
R S SP R
Sbjct: 664 RSRSRSPHYR 673
Score = 78.2 bits (191), Expect = 3e-14
Identities = 116/496 (23%), Positives = 181/496 (36%), Gaps = 95/496 (19%)
Query: 417 PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAA 476
P + + + + S G T ++ + E A KP + E + EE +
Sbjct: 148 PSEDEKKKLAEKKASIGYT------YEDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVI 201
Query: 477 DSVQQRRQYRRQNQQSSSDSGSSSSS------EDERPKRSHVKNGEVGRRRRHSPSRSAS 530
+ NQ+ +D +++ + R R + E + + A
Sbjct: 202 PDIDVEVDVDELNQEQVADLNKQATTYGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAM 261
Query: 531 PS---PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587
S R++++E + R R SPP RR SP+ P R + R R+ SP P
Sbjct: 262 YSGRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTPG 321
Query: 588 RRSP----SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP----PPKRRVSHSP 639
R + S + + T PP P + P+P +RR S S
Sbjct: 322 REEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSS 381
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGS------------------SPSRSTREARSPQPNKR 681
S + R S SS+ R+G S SRS R +RS +R
Sbjct: 382 SSSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRSRSRRYSRSRSRGRR 441
Query: 682 HSP-------------------SPRPRAPQTSSSPPPVRRGA-----SSSPQRRQSPSPS 717
HS PR R+ S S RRG SS + R S S S
Sbjct: 442 HSGGGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLS 501
Query: 718 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
R ++R+ ++ SPSP R S SRS S SP PA +K P +
Sbjct: 502 PSRSRSLTRS-------RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAA-------- 546
Query: 778 TNWSPAVPVKKAKSPTPS-----PSPPRNSDQEGGGKKKKKKKDKKHKKDKK-------H 825
SPAV K K+ + + P+ + QE + +K +++ K DKK
Sbjct: 547 ---SPAVGEKLKKTEPAAGKETGAAKPKLTPQEKLKLRMQKALNRQFKADKKAAQEKMIQ 603
Query: 826 KKHKKHKKEKAVAAAA 841
++H++ ++E + A A
Sbjct: 604 QEHERQEREDELRAMA 619
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 125 bits (313), Expect = 2e-28
Identities = 184/707 (26%), Positives = 267/707 (37%), Gaps = 114/707 (16%)
Query: 159 KESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
K + KR + RR + P+P S + R RS T+ P PAP +
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-------RSRAAGTEVGLPRPAPSARP 198
Query: 219 KTP-ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
+ P E P SV S E ++T EPSP + RP
Sbjct: 199 RPPTEGPRKSVS----SASEHSTT----------------EPSPAARRRPSAGGGLQRPA 238
Query: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
SRS S S T SP+ + P R R+ ++ + +P + P + TPPR+ P
Sbjct: 239 SRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 338 HRRSRSPVRRRRRSSASLSGSSS----SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
S SP+ ++ S SG+ + ++ + P PP + P SPSA
Sbjct: 297 GPLSSSPL-----ATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSA- 350
Query: 394 PPRRRHRPSPPATPPPKTRHSPT--PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESP 451
PP + PSPPATPP + S T P Q+ S ++ P + +T SP
Sbjct: 351 PPSLQTLPSPPATPPSQAPPSMTTPPMQA---PPSLQTIPPIQVPHSLT---------SP 398
Query: 452 SPAPKPRKVELS--ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509
S P + LS ++ G A R+ +S S +S+ D P +
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ 458
Query: 510 SHVK-NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP----SPA 564
+ + + SP+ S SP + SP P + P S
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSL 518
Query: 565 PPPRRRRTP---TPPPRRRTPS--PPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASP-- 617
PP + P T PP PS PPP + + +P +P ++ P+P P + SP
Sbjct: 519 APPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLT-TPHLETPPCPAPCPLQAPPSPLT 577
Query: 618 -PPPPKRRASPSPPPKRRVSHSPPPKQ--RSSPVTKRRS-----------PSLSSKHRKG 663
PPP + +PPP+ + + PP Q S P++ + P L +
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 664 SSPSRSTREARSPQ-PNK----------RHSPSPRPRAPQTSSSPPPVRRGAS------- 705
+SP S SPQ PN PSP +AP + + PPV A+
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 706 --SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763
++P + PSP P S TP P+ A+P Q +S +S S P +
Sbjct: 698 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 764 PP--------APPSPVQS--QSPSTNWSPAVPVKKAKSPTPS-PSPP 799
PP PPSP S SP P P A P + PSPP
Sbjct: 758 PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPP 804
Score = 98.2 bits (243), Expect = 3e-20
Identities = 150/571 (26%), Positives = 216/571 (37%), Gaps = 105/571 (18%)
Query: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS-----------RSPVRRRRRS 351
R ++++ + R P+ R R P PPPP + R P+ R
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 352 --------SASLSGSSSSSSSSRSRSPPKKPP---KRTSSPPRKTRRLSPSASPPRRRH- 399
SA +G + S+ +S SR+P +PP + +PP K P +SP R
Sbjct: 65 IGGATIPESAPRAGPTRSAGTS-SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 400 -RPSP-----------------PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTK 441
RP P AT PK S + R +P + ++
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPK--RSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 442 HKGTE---KRESPSPAPKP-----RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS 493
GTE R +PS P+P RK S SE AA ++R Q+ +
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA---RRRPSAGGGLQRPA 238
Query: 494 SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR---GRRRRSP 550
S S SSS++ P RS G R +P+ + P P+ Q P+ R+ +P
Sbjct: 239 SRSLSSSATPLSSPARS----GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP---PPRRRSPSPRRYSPPIQRRYSPS 607
+ P +P+P + R PP TP P PP +P +PP SPS
Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP-----SPS 349
Query: 608 PPPKRRTA-SPPPPPKRRASPS--PPPKRRVSHSPPPKQRSSPVT---KRRSPSLSSKHR 661
PP +T SPP P +A PS PP + +PP Q P+ SPSL +
Sbjct: 350 APPSLQTLPSPPATPPSQAPPSMTTPPMQ----APPSLQTIPPIQVPHSLTSPSLQAPPS 405
Query: 662 K-GSSPSRSTREARSPQPNKRHS---PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
S ++T SP HS SPR QT +S +SP R S P
Sbjct: 406 PLALSSLQATTSLGSPTLQATHSFLTMSPR----QTQAS--------LTSPSRPASTPPD 453
Query: 718 TRPIRRVSRTPEPKKIKKAASP------SPQSVRRVSSSRSV-SGSPEPAAKKPPAPPSP 770
+ P++ P ++ + SP SP ++ + + S+ S SP+ PP
Sbjct: 454 SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLE 513
Query: 771 VQSQ--SPSTNWSPAVPVKKAKSPTPSPSPP 799
QS PS PA PS +PP
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPP 544
Score = 90.1 bits (222), Expect = 8e-18
Identities = 178/756 (23%), Positives = 260/756 (34%), Gaps = 120/756 (15%)
Query: 143 SMKKQDEDKDKRDKEEKESSREKRERSRSPRRR------------KSRSPSPRRRSSPVR 190
S + + + R S E S + RRR +S S S SSP R
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 254
Query: 191 R-ERKRSHSRSPRHRTKS--------RSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
R R+P H ++ R P P +K+ P L S P + S
Sbjct: 255 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPSPSG 311
Query: 242 SDILKVPKPE----PIPEPKEPSPEKNSKKE-KEKEKTRPRSRSRSKSRSRT--RSRSPS 294
+ VP P+ P+P PSP + + P S S T PS
Sbjct: 312 TKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPS 371
Query: 295 HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354
T P + ++ P + P PS + P + SP + S +
Sbjct: 372 MTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLT 431
Query: 355 LSG----SSSSSSSSRSRSPPKKPPKRT-----SSPPRKTRRLSPSASP----------- 394
+S +S +S S + +PP PP + +SPP +T LSP+ SP
Sbjct: 432 MSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTS-LSPAVSPLSSPLTIHPLQ 490
Query: 395 ---PRRRHRPSPPAT----PPPKTRHSPTPQQSNRTRKSRVSVSP-------------GR 434
H P P + PP +T+ S P S +T + ++ P
Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPP-SLQTPPASLTTPPLENLPSLAPPPLQTA 549
Query: 435 TSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSS 494
++ T H T +P P P + E S
Sbjct: 550 SAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609
Query: 495 DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS--ASPSPRKRQKETSPRGRRRRSPSP 552
++ + P + + SP S A+PSP+ + SP P
Sbjct: 610 PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 553 -PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS--PPPRRRSPSPRRYSPPIQRRYSPSP- 608
PP + SP +PP TP P + PS PP + PSP SPP+ +P P
Sbjct: 670 SPPVQAPFSPPASPPVSPSATP---PSQAPPSLAAPPLQVPPSPPA-SPPMSPSATPPPQ 725
Query: 609 -------PPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQ--RSSPVTKRRSPSLSSK 659
PP + SPP P S +PPP+ + PP Q S P + SP +K
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL--AK 783
Query: 660 HRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS------SSPPPVRRGASSSPQRRQS 713
+ P+ +T ++ P P +P S ++PPP ++P +
Sbjct: 784 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 843
Query: 714 PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS 773
PSP P + R P +P P + SVSG A P PP P S
Sbjct: 844 PSPPASPTLQAPRRPP--------TPGPDT--------SVSGPRLTLALAPGPPPPP--S 885
Query: 774 QSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQ--EGG 807
+SPS+ S + S T +P R D EGG
Sbjct: 886 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 921
Score = 84.7 bits (208), Expect = 3e-16
Identities = 150/643 (23%), Positives = 220/643 (34%), Gaps = 96/643 (14%)
Query: 187 SPVRRERKRSHSRSPRHRTKS-RSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDIL 245
SP + + SPR S SPS +P L P P +Q + S
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS----- 474
Query: 246 KVPKPEPIPEPKEPSP-EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304
P P+ P P + S + S +++ PS P +
Sbjct: 475 --PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT 532
Query: 305 RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
P P P + S TP PP P ++P + L+ + S
Sbjct: 533 PPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAP-------PSPLTTPPPETPS 585
Query: 365 SRSRSPPKKPPKRTSSPPR--KTRRLSPSASPPRR----------RHRPSPPATPPPKTR 412
S + PP+ PP S P + + LSP A+PP + + PSPPA+PP
Sbjct: 586 SIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL 645
Query: 413 HSPTPQQSNR--TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
+P+PQ N + SP + ++P P V S + +
Sbjct: 646 ATPSPQAPNALAVHLLQAPFSP----------PPSPPVQAPFSPPASPPVSPSATPPSQA 695
Query: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP--SRS 528
AA +Q + +S S++ + P +V SP S S
Sbjct: 696 PPSLAAPPLQVP-----PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750
Query: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
A+P PR +P + P PP SP PPP+ PP + PSPP
Sbjct: 751 ATPPPRVPPLLAAPP---LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
Query: 589 RSPSPRRYSPPIQRRYSP--SPPPKRRTA-------SPPPPPKR------RASPSPPPKR 633
+P +SP SP +PPP+ PP PP R P+P P
Sbjct: 808 PGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 865
Query: 634 RVS---------HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS-PQPNKRHS 683
VS PPP SP + P L+ +S R S P+ S
Sbjct: 866 SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Query: 684 PSP-------RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP-----IRRVSRTPEPK 731
P P P A +PP RGA +P P+T P + + T P
Sbjct: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAP---LPWPPATGPGSADGLCTIYETEGP- 981
Query: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
++A+P+P ++ S + G A + SP Q++
Sbjct: 982 ---ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 1021
Score = 77.4 bits (189), Expect = 6e-14
Identities = 88/329 (26%), Positives = 127/329 (38%), Gaps = 40/329 (12%)
Query: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
+G+SS + RP S GR R P+++ SP P S GR + P P
Sbjct: 83 AGTSSRNPASRPPAS-------GRGERAPPAKNTSPGP------VSSPGRASGTTRPGPL 129
Query: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS--PSPRRYSPPIQRRYS-------- 605
++ A R T P+R S RR + P+P SP + RR
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
Query: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP---VTKRRSPSLSSKHRK 662
P P P R P P++ S S SP ++R S + + S SLSS
Sbjct: 190 PRPAPSARPRPPTEGPRKSVS-SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
Query: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP---PPVRRGA------SSSPQRRQS 713
SSP+RS AR H P+P+ Q P PP + A SSSP S
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS 308
Query: 714 PSPS-TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ 772
PS + RP+ P + PSP + + +P P+ + P+PP+
Sbjct: 309 PSGTKARPVPPPDNAATP--LPATLPPSPPLATPLPLAPPSPSAP-PSLQTLPSPPATPP 365
Query: 773 SQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
SQ+P + +P + + P P +
Sbjct: 366 SQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 124 bits (310), Expect = 5e-28
Identities = 135/645 (20%), Positives = 257/645 (39%), Gaps = 81/645 (12%)
Query: 93 LNGKNAREFMGELWPLLLSAQENIAGIPSAFLELK---KEEIK------------QRQIE 137
L G+ R G P+ S E + IPS +K +E+IK + Q E
Sbjct: 406 LEGEECRIGFG---PIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTE 462
Query: 138 QEKLASMKKQDEDKDKRDKE-------EKESSREKRERSRSPRRRKSRSPSPRRRSSPVR 190
+ ++ ++E+K+ +++E E+E + E ++SP ++ SP + SPV+
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPE-KEAKSPVK 521
Query: 191 RERKR-SHSRSP-RHRTKSRSPSPAPEK-KEKTPELPEPSVKVKEPSVQEATSTSDI--- 244
E K + ++SP + KS + +PEK K E + + K P +EA S +++
Sbjct: 522 EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSP 581
Query: 245 --LKVPKPEPIPEPKEP-SPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR 301
K P E P E SPEK KE+ K S + +KS + ++SP+ + +
Sbjct: 582 EKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAK----SPAEAKSPVKEEAKSPAEVKSPEK 637
Query: 302 HRS--RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRS--SASLSG 357
+S + + SP + SP + + ++P +++SPV+ +S A
Sbjct: 638 AKSPTKEEAKSPEKAKSPEKEEA---KSP----------EKAKSPVKAEAKSPEKAKSPV 684
Query: 358 SSSSSSSSRSRSPPK---KPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHS 414
+ + S +++SP K K P++ SP ++ + A P + +P P +
Sbjct: 685 KAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEA 744
Query: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPK-PRKVELSESEEDKGGKM 473
+P+++ K++ K + K K E+ SPA K P K + EE K +
Sbjct: 745 KSPEKAKSPEKAKT------LDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEK 798
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
A + + + + + + S E+E+P+ VK +P+ +
Sbjct: 799 AKSPLKEDAK--APEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK 856
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+ +KE +P ++ +P P ++ P + + P P + +P+
Sbjct: 857 KDSKKEEAP---KKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPA- 912
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS 653
++ + P K A P + PS P +++ P+++ + K +
Sbjct: 913 -----KVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKK---EAAPEKKDTKEEKAKK 964
Query: 654 PSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
P K + T ++ P K Q S PP
Sbjct: 965 PEEKPKTEAKAKEDDKTL-SKEPSKPKAEKAEKSSSTDQKDSKPP 1008
Score = 124 bits (310), Expect = 5e-28
Identities = 124/605 (20%), Positives = 236/605 (39%), Gaps = 64/605 (10%)
Query: 215 EKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP---KEPSPEKNSKKEKEK 271
E+K K E E + E +E T ++ + + E E +E E+ ++ +E+
Sbjct: 441 EEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEE 500
Query: 272 EKTRPRSRSRS-----KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
K+ P + S KS + ++SP+ + + ++S P SP + SP +
Sbjct: 501 TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKS----PAEVKSPEKAKSPAKE 556
Query: 327 TPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR--SRSPPK-KPPKRTSSPPR 383
+ PP ++SP + +S A + + S ++ ++SP + K P++ SP +
Sbjct: 557 EA--KSPP-----EAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 384 KTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHK 443
+ + A P + SP P+ SPT +++ K++ SP +
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK---SPEK--------- 657
Query: 444 GTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE 503
E+ +SP A P K E E+ K A A S ++ + ++ +S + S E
Sbjct: 658 --EEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEE 715
Query: 504 DERPK--RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP 561
+ P+ +S VK + SP + + SP K + + +SP + +
Sbjct: 716 AKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEAR 775
Query: 562 SPAPP-PRRRRTPT-----PPPRRRTP----SPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611
SPA P + ++P P + ++P + P + P P++ P
Sbjct: 776 SPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKP----- 830
Query: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG-SSPSRST 670
+ PPK+ P + K+ +P + P + K P S
Sbjct: 831 -QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESK 889
Query: 671 REARSPQ-PNKRHSPSPRPRAP-----QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724
EA+ + +K+ P+P AP + + P A P ++ PS +P +
Sbjct: 890 VEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS-KPAEKK 948
Query: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAV 784
PE K K+ + P+ + + + +K+P P + +S ST+ +
Sbjct: 949 EAAPEKKDTKEEKAKKPE--EKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSK 1006
Query: 785 PVKKA 789
P +KA
Sbjct: 1007 PPEKA 1011
Score = 119 bits (299), Expect = 1e-26
Identities = 114/566 (20%), Positives = 222/566 (39%), Gaps = 55/566 (9%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQD------EDKDKRDKEEKESSREKRE---RSRSPRRR 175
E K+EE K+ + +E+ A +++ E+ +KE K +E+ + ++SP +
Sbjct: 477 EAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKE 536
Query: 176 KSRSP----SPRRRSSPVRRERKRSHSRSPRHRTKSRSP----------SPAPEKKEKTP 221
+++SP SP + SP + E K + +++SP SPA E+ +
Sbjct: 537 EAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA 596
Query: 222 ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKE-PSPEKNSKKEKEKEKTRPRSRS 280
E P K K P +EA S ++ K P E P E SPEK KE+ K+ +++S
Sbjct: 597 EAKSPE-KAKSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 281 RSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSP---RRRTPPRRMPPPPR 337
K +++ ++ S + + +++S SP + SP ++P + P
Sbjct: 655 PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK-KPPKRTSSPPRKTRRLSPSASPPR 396
+S + + A + S ++SP K K P++ + K SP A P
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK----SPEAKTPA 770
Query: 397 RRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA-- 454
+ SP P K + SP ++ K++ SP + K + + +K E SP
Sbjct: 771 KEEARSPADKFPEKAK-SPVKEEVKSPEKAK---SPLKEDAKAPEKEIPKKEEVKSPVKE 826
Query: 455 -PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
KP++V++ E + + A A + ++ ++ + ++ E + P K
Sbjct: 827 EEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPK 886
Query: 514 NGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTP 573
+V ++ + + P+P K +P + P +
Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKE--------------APAKVEVKEDAKPKEKTEVAKKE 932
Query: 574 TPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR 633
+ + PS P ++ +P + ++ P PK + PS P
Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Query: 634 RVSHSPPPKQRSSPVTKRRSPSLSSK 659
+ S Q+ S ++ + ++K
Sbjct: 993 KAEKSSSTDQKDSKPPEKATEDKAAK 1018
Score = 103 bits (256), Expect = 9e-22
Identities = 110/553 (19%), Positives = 194/553 (35%), Gaps = 53/553 (9%)
Query: 360 SSSSSSRSRSPPKK----PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
+ ++SPP + P K SP ++ + A P + SP P+ SP
Sbjct: 494 AEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSP 553
Query: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAA 475
+++ P S + + K + +SP A P K E E K + A
Sbjct: 554 AKEEAKSP--------PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605
Query: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535
+ ++ + ++ S + + +S K + SP + + SP K
Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEK 665
Query: 536 RQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRR 595
+ + P +SP A P + +P + P + + SP +
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS----PVKEEAKSPEK 721
Query: 596 YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS 655
P++ K P++ SP K + P+ ++ + RSP+
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPE---KAKTLDVKSPEAKTPAKEEARSPA 778
Query: 656 LSSKHRKGSSPSRSTREARSPQ----PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR 711
K SP + E +SP+ P K + +P P+ PV+ PQ
Sbjct: 779 -DKFPEKAKSPVKE--EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKE--EEKPQEV 833
Query: 712 QSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPV 771
+ P + PK +K S ++ ++ + V EPA +KP S V
Sbjct: 834 KVKEPPKKA-EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKE--SKV 890
Query: 772 QSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKK-DKKHKKDKKHKKHKK 830
+++ K K PTP P + + K K+K + KK D K K+ K
Sbjct: 891 EAKKEEAE-------DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943
Query: 831 HKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREK 890
++K AA +EE PE K +TE++A+++ L K +
Sbjct: 944 PAEKKE--------------AAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Query: 891 ALRSMRKAQVSPQ 903
K+ + Q
Sbjct: 990 KAEKAEKSSSTDQ 1002
Score = 90.1 bits (222), Expect = 8e-18
Identities = 100/455 (21%), Positives = 180/455 (39%), Gaps = 53/455 (11%)
Query: 456 KPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNG 515
K + VE SE E + + ++ + ++ ++ E+E + + G
Sbjct: 443 KIKVVEKSEKET-----VIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGG 497
Query: 516 EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP---PPTRRRRSPSPAPPPRRRRT 572
E SP + SP K K SP +SP+ P +SP+ P + ++
Sbjct: 498 E---EETKSPPAEEAASPEKEAK--SPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKS 552
Query: 573 PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPK 632
P + SPP + SP + + P + A P K P K
Sbjct: 553 PA---KEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 633 RRVSHSPPPKQRSSPVTKR-RSPSLSSKHRKGSSPSRSTREARSPQ----PNKRHSPSP- 686
P + SPV + +SP+ K SP++ EA+SP+ P K + SP
Sbjct: 610 EEAKS---PAEAKSPVKEEAKSPAEVKSPEKAKSPTKE--EAKSPEKAKSPEKEEAKSPE 664
Query: 687 RPRAPQTSSSPPPVR-----RGASSSPQRRQSP------SP--STRPIRRVSRTPEPKKI 733
+ ++P + + P + + + SP++ +SP SP + P++ +++PE K
Sbjct: 665 KAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
Query: 734 ---------KKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA-PPSPVQSQSPSTNWSPA 783
+KA SP + + ++S + K P A P+ +++SP+ +
Sbjct: 725 PVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEK 784
Query: 784 V--PVK-KAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA 840
PVK + KSP + SP + + + KK++ K K+++ + K K+ A
Sbjct: 785 AKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEE 844
Query: 841 AAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESE 875
A TP + + AP+PK E + E
Sbjct: 845 EKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKE 879
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 118 bits (295), Expect = 3e-26
Identities = 167/698 (23%), Positives = 282/698 (40%), Gaps = 120/698 (17%)
Query: 183 RRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEP-SVQEATST 241
RR+ RRER R S SP +P+PAP P + + K +EA S+
Sbjct: 483 RRKILTQRRERYRQRSPSP-------APAPAPAAAAGPPTRKKSRRERKRSGEAKEAASS 535
Query: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRR 301
S + P P P+ +SKK + +++ +P S + S +R R+RSRS S R
Sbjct: 536 SSGTQ-------PAPPAPASPWDSKKHRSRDR-KPGSHASSSARRRSRSRSRS-----RS 582
Query: 302 HRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
R RSRS + RRR RR S +R RR PP S S RR R G S
Sbjct: 583 TRRRSRS-TDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSK 641
Query: 362 SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPAT---PPPKTRHSPTPQ 418
RSRS + KR+ K +P+ +PP PS + + R + P
Sbjct: 642 KKKKRSRS---RGEKRSGDGSEK----APAPAPP-----PSGSTSCGDRDSRRRGAVPPS 689
Query: 419 QSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE----EDKGGKMA 474
+ T ++ T G++ K + SP+PA P++ L +SE E++GGK +
Sbjct: 690 IQDLTDHDLFAIKRTITVGRL--DKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSS 747
Query: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
D ++ S + SSSSS ++ +R + G+ R R R S
Sbjct: 748 QKD------------RRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKA 795
Query: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPP-----RRRTPSPPPRRR 589
+ KE++P P PP + S S + R+ R S P +
Sbjct: 796 RPPKESAPSS--GPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKD 853
Query: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649
+ S S I ++S R + SP P RA P+ K + P K +
Sbjct: 854 AASAGLGS--IGVKFSRD----RESRSPFLKPDERA-PTEMAKAAPGSTKPKKTK----V 902
Query: 650 KRRSPSLSSKHRKG-SSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
K ++ + +K KG + PS++ ++ RS S +++ + S
Sbjct: 903 KAKAGAKKTKGTKGKTKPSKTRKKVRS------------GGGSGGSGGQVSLKKSKADS- 949
Query: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768
S + T+ S + E + K ++P P++ PP P
Sbjct: 950 ---CSQAAGTKGAEETSWSGEERAAKVPSTPPPKAA-------------------PPPPA 987
Query: 769 SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG--GGKKKKKKKDKKHKKDKKHK 826
SQ+ ++ K+P S P +++ G GG +++++++++ +++++ +
Sbjct: 988 LTPDSQTVDSS---------CKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEE 1038
Query: 827 KHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVA 864
+ + AAAA + P+A + A + A++ P +
Sbjct: 1039 EQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAS 1076
Score = 108 bits (271), Expect = 2e-23
Identities = 198/872 (22%), Positives = 291/872 (33%), Gaps = 198/872 (22%)
Query: 171 SPRRRKSRSPSPRRRS------SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL- 223
SP+ SR R + P S S SP S SPSP P P
Sbjct: 161 SPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAP 220
Query: 224 PEPSVKVKEP--SVQEATSTSDILKVPKPEPIPEPKE------------PSPEKNSKKEK 269
P P + +P EA S P PE +P E PSPE+ ++E+
Sbjct: 221 PAPRFDIYDPFHPTDEAYSPP-----PAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEE 275
Query: 270 EKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP 329
E+E+ + S++ SR S S+ + P P +P+ + TP
Sbjct: 276 EEEE-EEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPT--QPTPA 332
Query: 330 RRMPPPPRHRRSRSPVRRR-----RRSSASLSGSSS---SSSSSRSRSPPKKPPKRTS-- 379
PP R+ +RRR + A G S ++ + PP PP +
Sbjct: 333 PGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAALPPPLLPPGDSEIE 392
Query: 380 -----SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
P + R P R RP+P A+ P + P P
Sbjct: 393 EGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPPAPRAPEGDDFLSLHAE 452
Query: 435 TSGK------------------------------VTKHKGTEKRESPSPAPKPRKVELSE 464
+ G+ +T+ + ++ SPSPAP P
Sbjct: 453 SDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAPAP----- 507
Query: 465 SEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP-----------KRSHVK 513
AAA R++ RR+ ++S ++SSS +P K+ +
Sbjct: 508 ---------AAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASPWDSKKHRSR 558
Query: 514 NGEVGRR-----RRHSPSRSASPSPRKRQKETS-PRGRRRRSPSPPPTRRRRSPSPAPPP 567
+ + G RR S SRS S S R+R + T RG RRS S RRRR + PP
Sbjct: 559 DRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPA 618
Query: 568 RRRRTPTPPPRRR--------TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
+ + R R + R RS +R ++ +P+PPP T+
Sbjct: 619 TSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDR 678
Query: 620 PPKRRASPSPPPKRRVSH--------------------SPPPKQRSSPVTKRR----SPS 655
+RR + P + H P P SSP KR S
Sbjct: 679 DSRRRGAVPPSIQDLTDHDLFAIKRTITVGRLDKSDPRGPSPAPASSP--KREVLYDSEG 736
Query: 656 LSSKHRKGSSPSRSTRE--ARSPQPNKRHSPSPR-------------------------- 687
LS + R G S + R A S + R S R
Sbjct: 737 LSGEERGGKSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKAR 796
Query: 688 -PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR 746
P+ SS PPP +S S S S S+R ++ S+ I++ S + +
Sbjct: 797 PPKESAPSSGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKV--AVLIREGVSSTTPAKDA 854
Query: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806
S+ G + +S+SP P + AK+ S P + +
Sbjct: 855 ASAGLGSIGVKFSRDR---------ESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAK 905
Query: 807 GGKKKKKKKDKKHKKDKKHKKHKKH------------KKEKAVAAAAAAAVTPAAIAA-- 852
G KK K K K K KK + KK KA + + AA A +
Sbjct: 906 AGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWS 965
Query: 853 ----ATTTLAQEEPVAAPEPKKET-ESEAEDN 879
A + P AAP P T +S+ D+
Sbjct: 966 GEERAAKVPSTPPPKAAPPPPALTPDSQTVDS 997
Score = 80.5 bits (197), Expect = 7e-15
Identities = 120/523 (22%), Positives = 189/523 (36%), Gaps = 84/523 (16%)
Query: 132 KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP-RRRSSPVR 190
++R + + S +++ D+R + SR R R + RRR+S SP P SS R
Sbjct: 571 RRRSRSRSRSRSTRRRSRSTDRR----RGGSRRSRSREKRRRRRRSASPPPATSSSSSSR 626
Query: 191 RERKRSH------SRSPRHRTKSRSPSPAPEKKEKTP-ELPEPSVKVK------------ 231
RER R S+ + R++SR + + EK P P PS
Sbjct: 627 RERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAV 686
Query: 232 EPSVQEATSTSDILKVPKPEPI-----PEPKEPSPEKNSKKEKE----KEKTRPRSR-SR 281
PS+Q+ T D+ + + + +P+ PSP S ++E E R +
Sbjct: 687 PPSIQDLTD-HDLFAIKRTITVGRLDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGK 745
Query: 282 SKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS 341
S + R RS + S + R SR ++ R R R R R+ ++ PP S
Sbjct: 746 SSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRS-SKKARPPKESAPS 804
Query: 342 RSPVRRRRRSSASLSGSSSSSSSSR----------------SRSPPKKPPKRTS------ 379
P + SS S S SSSSS SSR S + P K
Sbjct: 805 SGPPPKPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGV 864
Query: 380 --SPPRKTRR--LSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
S R++R L P P + +P +T P KT+ + +T+ ++ P +T
Sbjct: 865 KFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTK-VKAKAGAKKTKGTKGKTKPSKT 923
Query: 436 SGKVTKHKGT-----------EKRESPSPAPKPRKV-ELSESEEDKGGKMAAADSVQQRR 483
KV G+ K +S S A + E S S E++ K+ + +
Sbjct: 924 RKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAP 983
Query: 484 QYRRQNQQSSSDSGSSSSSE-----DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQK 538
S + S + E +E + + V+ G ++
Sbjct: 984 PPPALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPA 1043
Query: 539 ETSPRGRRRRSPSPPP----TRRRRSPSPAPPPRRRRTPTPPP 577
T+ +PS P T P R + PT PP
Sbjct: 1044 TTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPP 1086
Score = 71.6 bits (174), Expect = 3e-12
Identities = 148/720 (20%), Positives = 243/720 (33%), Gaps = 97/720 (13%)
Query: 162 SREKRERSRSPRRRKSRSPSPRRRS-SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
S++ R R R P S S R RS S R R+RS S R RS S ++ +
Sbjct: 552 SKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRR 611
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
P P+ S +E + ++ K+K+K RSRS
Sbjct: 612 SASPPPATSSSSSSRRE-------------------RHRGKHRDGGGSKKKKK---RSRS 649
Query: 281 RSKSRSRTRSRS-------PSHTRPRRRHRSRSRSYSP---------------------- 311
R + RS S PS + SR R P
Sbjct: 650 RGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRRRGAVPPSIQDLTDHDLFAIKRTITVGR 709
Query: 312 -----RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366
R PSP SP+R R +S + RRRS A+ S SSS SR
Sbjct: 710 LDKSDPRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSSSSSREKGSR 769
Query: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
++ R R R S A PP+ +P + PPPK P S+ + S
Sbjct: 770 RKALDGGDRDRDRDRDRDRDRSSKKARPPK---ESAPSSGPPPK------PPVSSGSGSS 820
Query: 427 RVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYR 486
S S K+ RE S + P K S G K + + R +
Sbjct: 821 SSSSSCSSRKVKLQSKVAVLIREGVS-STTPAKDAASAGLGSIGVKFSR--DRESRSPFL 877
Query: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRR 546
+ ++++ ++ ++ +PK++ VK ++ + + ++ RK+ + G
Sbjct: 878 KPDERAPTEMAKAAPG-STKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGS 936
Query: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR--RTPSPPPRRRSPSPRRYSPPIQRRY 604
S ++ A T R + PS PP + +P P +P Q
Sbjct: 937 GGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVD 996
Query: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664
S P+ + P A + ++ + + P+ ++ +
Sbjct: 997 SSCKTPE--VSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEE--EEEQQPATTTATSTAA 1052
Query: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724
+ + A S + P R Q + PPP+ + S + + +
Sbjct: 1053 AAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTAL--L 1110
Query: 725 SRTPEPKKIKKA-ASPSPQSVRRVSSSR----SVSGSPEPAAKKPPAPPSPVQSQSPSTN 779
+ E +A A Q+ ++ S R S+ +P P PP P P
Sbjct: 1111 FKMEEANLASRAKAQELIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLPG-- 1168
Query: 780 WSPAVPVKKAKS--PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAV 837
++P+ S PTP+ + +EG + + K+ K K H +E+AV
Sbjct: 1169 ---SLPLGGCGSTPPTPTGLAATSDKREGSSSSEGRGDTDKYLK-------KLHTQERAV 1218
Score = 61.6 bits (148), Expect = 3e-09
Identities = 130/584 (22%), Positives = 191/584 (32%), Gaps = 133/584 (22%)
Query: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
P P S P R R+ ++S S+SS + +R +PP S S S
Sbjct: 139 PIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARHLTLGTGDGGPAPPPAPSSASSSPS 198
Query: 394 PPRRRHRPSPPATPPPKTRHS-------------PTPQQSNRTRKSRVSVSPGRTSG-KV 439
P PSPP PPP + PT + + P +G
Sbjct: 199 PSPSSSSPSPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNP 258
Query: 440 TKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS 499
+ GT E + + E + EE++G + + + N S G
Sbjct: 259 SSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDE 318
Query: 500 SSSEDERPKR------------SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR 547
S D +P + S +G + RR + + + K E G
Sbjct: 319 SPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVTAGGAA 378
Query: 548 RSPS---------------PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592
P P R + S P R PT P TP+ P + P+
Sbjct: 379 LPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPT-PAASATPTAQPLPQPPA 437
Query: 593 PRRYSPPIQRRYS-----------------PSPPP------------KRRTASPPPPPKR 623
PR +P S P+P P +R+ + R
Sbjct: 438 PR--APEGDDFLSLHAESDGEGALQVDLGEPAPAPPAADSRWGGLDLRRKILTQRRERYR 495
Query: 624 RASPSPPPKRRVSHSPPPKQRSSPVTK---RRSPSLSSKHRKGSSPSRSTREA----RSP 676
+ SPSP P +P P + P T+ RR S + ++ +S S T+ A SP
Sbjct: 496 QRSPSPAP------APAPAAAAGPPTRKKSRRERKRSGEAKEAASSSSGTQPAPPAPASP 549
Query: 677 QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKA 736
+K+H R R P + ASSS +RR +R RR SR+ +
Sbjct: 550 WDSKKH--RSRDRKPGSH---------ASSSARRRSRSRSRSRSTRRRSRSTDR------ 592
Query: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSP 796
RR S RS S ++ +PP S S S
Sbjct: 593 --------RRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRR----------------- 627
Query: 797 SPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAA 840
R ++GGG KKKKK+ + + +K EKA A A
Sbjct: 628 ERHRGKHRDGGGSKKKKKRSR-----SRGEKRSGDGSEKAPAPA 666
Score = 40.4 bits (93), Expect = 0.008
Identities = 43/185 (23%), Positives = 71/185 (38%), Gaps = 25/185 (13%)
Query: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRT--PEPK 731
R P P S PR RA +T G + SPQ S R + + P P
Sbjct: 137 RDPIPLPVPSLLPRLRAWRT---------GKTVSPQSNSSRPTCARHLTLGTGDGGPAPP 187
Query: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
+AS SP SS P PA PPAP + + P P +A S
Sbjct: 188 PAPSSASSSPSPSPSSSSPSPPPPPPPPAPPAPPAPRFDI--------YDPFHPTDEAYS 239
Query: 792 PTPSPS------PPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845
P P+P P S+ +++++ +++++ ++ + ++E + + +
Sbjct: 240 PPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISE 299
Query: 846 TPAAI 850
T A I
Sbjct: 300 TLAGI 304
>gi|50083281 KIAA1853 protein [Homo sapiens]
Length = 611
Score = 117 bits (292), Expect = 6e-26
Identities = 138/511 (27%), Positives = 200/511 (39%), Gaps = 69/511 (13%)
Query: 259 PSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS-----RSRSYSPRR 313
P P KK+K+K + R RS S S S + + ++ +R RS R S SP+
Sbjct: 102 PPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKS 161
Query: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK 373
+ +R + R+ PR+ RHR R P RS +S S SS S R RSP +
Sbjct: 162 KRRDEKRHKKQSRSRPRK---SHRHRHHRCP----SRSQSSESRPSSCESRHRGRSPEEG 214
Query: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPP----------------ATPPPKTRHSPTP 417
R R ++ L + + PS P + + +P
Sbjct: 215 QKSRRRHSRRCSKTLCKDSPEAQSSRPPSQPLQMLGYLSARGVITGSGSAADLFTKTASP 274
Query: 418 QQSNRTRKSRV-----SVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE----------- 461
++R R + SP T + +G EK K R++
Sbjct: 275 LTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSF 334
Query: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRR 521
+ S ++KG + + R+ R + SS RS G R
Sbjct: 335 TTSSPQNKGAMLENLSPTSRGRESRGFQSPCLECAEVKKSSLVPSTARSSPMKG-CSRSS 393
Query: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
++ +RS+S S R SPR + RS S RSPS + +R PP R +
Sbjct: 394 SYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKR----SPPSRSS 449
Query: 582 PSPPPRRRSPSPRRYSPPIQR--RYSPSPPP--------KRRTASPPPPPKRRASPSPPP 631
S RRSPS RYSP +R +YS +RR + P +RR SPS
Sbjct: 450 RS----RRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLE 505
Query: 632 KRRVSHS---PPPKQRSSPVTKRRSPSLSSKHRKGS--SPSRSTREARSPQPNKRHSPSP 686
RR++ + P P R SP + S SS + S S SRS +RS ++R S +
Sbjct: 506 ARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRT- 564
Query: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
R + +S SP P R S S R +S S S
Sbjct: 565 RTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS 595
Score = 77.4 bits (189), Expect = 6e-14
Identities = 108/500 (21%), Positives = 181/500 (36%), Gaps = 71/500 (14%)
Query: 432 PGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQ 491
P + GK K K T K+ S + P V+ + + K K +RR + ++ +
Sbjct: 103 PPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHK--------RRRSFSKKRRH 154
Query: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHS-PSRSASPSPRKRQKETSPRGRRRRSP 550
SSS S E K+S + + R R H PSRS S R E+ RGR SP
Sbjct: 155 SSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGR---SP 211
Query: 551 SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR---------------------R 589
RRR + +P R PS P + +
Sbjct: 212 EEGQKSRRRHSRRCSKTLCKDSPEAQSSR-PPSQPLQMLGYLSARGVITGSGSAADLFTK 270
Query: 590 SPSPRRYSPPIQRRYSP----SPPPKRRTASPPPPPKRRASPSPP-PKRRVSHSPPPKQR 644
+ SP S + Y S PP +T+S + + SPS K R +S
Sbjct: 271 TASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSRGQEKGSPSGGLSKSRELNSGNTSDS 330
Query: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
+ T SP + SP+ RE+R Q SP + SS P R +
Sbjct: 331 GNSFTTS-SPQNKGAMLENLSPTSRGRESRGFQ-----SPCLECAEVKKSSLVPSTARSS 384
Query: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKP 764
R S STR SR+P P+ + S + S SRS S S + + P
Sbjct: 385 PMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP 444
Query: 765 PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
P+ S + + +SP+ P+ S+++ +++++++ ++ +
Sbjct: 445 PSRSSRSRRSPSYSRYSPS-----------RERDPKYSEKD----SQQRERERARRRRRS 489
Query: 825 HKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLE 884
+ +K +++ +P+ + A T A++ P+ P +
Sbjct: 490 YSPMRKRRRD-----------SPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYS 538
Query: 885 KHLREKALRSMRKAQVSPQS 904
A RS +++ +S
Sbjct: 539 SSSSRSASRSYSRSRSRSRS 558
Score = 76.3 bits (186), Expect = 1e-13
Identities = 74/236 (31%), Positives = 93/236 (39%), Gaps = 23/236 (9%)
Query: 164 EKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS-RSPRHRTKSRSPSPAPEKKEKTPE 222
E ++ S P +S RSS R SHS RSP R R EK
Sbjct: 370 EVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSY 429
Query: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
PS K + +S + P +E P+ + K +++E+ R R R RS
Sbjct: 430 SRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRERERARRRRRS 489
Query: 283 KSRSRTRSR-SPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR----------TPPRR 331
S R R R SPSH R R S R+RP P RPSP +
Sbjct: 490 YSPMRKRRRDSPSHLEAR-------RITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSS 542
Query: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR 387
+ RSRS R RRRS +SSSSSSRS SP + R+ S R R
Sbjct: 543 RSASRSYSRSRSRSRSRRRSRT----RTSSSSSSRSPSPGSRSRSRSRSRSRSRSR 594
Score = 75.5 bits (184), Expect = 2e-13
Identities = 119/483 (24%), Positives = 189/483 (39%), Gaps = 66/483 (13%)
Query: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSR-SPRRRKSR 178
PS + KK+ K+ + + + + ++EK ++ R R R S R R R
Sbjct: 128 PSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKSHRHRHHR 187
Query: 179 SPSPRRRSSPVRRE--RKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS-- 234
PS R +SS R R RSP KSR K + PE + + PS
Sbjct: 188 CPS-RSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPE-AQSSRPPSQP 245
Query: 235 ------------VQEATSTSDIL-KVPKPEPIPEPKE------------PSPEKNSKKEK 269
+ + S +D+ K P + PS + +S + +
Sbjct: 246 LQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSARSR 305
Query: 270 EKEKTRPR---SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
+EK P S+SR + T S T +++ + P+ R R S +
Sbjct: 306 GQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKG---AMLENLSPTSRGRESRGFQ 362
Query: 327 TP------PRRMPPPPRHRRSRSPVRRRRRSS--ASLSGSSSSSSSSRSRSPPKKPPKRT 378
+P ++ P RS SP++ RSS AS SS SS S R+ P+ R+
Sbjct: 363 SPCLECAEVKKSSLVPSTARS-SPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRS 421
Query: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK 438
+S +++ SPS S + + SPP+ ++R SP+ + + +R+ S + S +
Sbjct: 422 TSSEKRSYSRSPSYS--SKSGKRSPPSR-SSRSRRSPSYSRYSPSRERDPKYSE-KDSQQ 477
Query: 439 VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSS----- 493
+ + +R S SP K R+ S E + + ++ Y R + SS
Sbjct: 478 RERERARRRRRSYSPMRKRRRDSPSHLEARR-----ITSARKRPIPYYRPSPSSSGSLSS 532
Query: 494 -----SDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548
S S S S+S RS ++ R R S S S SPSP R + S R R
Sbjct: 533 TSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSR 592
Query: 549 SPS 551
S S
Sbjct: 593 SRS 595
Score = 72.0 bits (175), Expect = 2e-12
Identities = 137/621 (22%), Positives = 217/621 (34%), Gaps = 82/621 (13%)
Query: 247 VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRS 306
+P+ EP P P+ + S+K + T P + S R +T R R S
Sbjct: 42 LPRTEPQNNPVVPAQDGPSEKLGQHLATEPLG-TNSWERDKT-------CRELGATRGHS 93
Query: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRS----PVRRRRRSSASLSGSSSSS 362
S+ P P R +++ R+ + RRS S PV+++++ S S
Sbjct: 94 ASHDKDLTPPPSSRGKKKKKKSTRK-----KRRRSSSYSPSPVKKKKKKS--------SK 140
Query: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422
R RS KK +SSP K R +RH+ + P RH +
Sbjct: 141 KHKRRRSFSKKRRHSSSSPKSKRR--------DEKRHKKQSRSRPRKSHRHR------HH 186
Query: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482
SR S R S ++H+G SP K R+ + A S +
Sbjct: 187 RCPSRSQSSESRPSSCESRHRG----RSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSRPP 242
Query: 483 RQYRRQNQQSSSDS--GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET 540
Q + S+ S S+ D K + GR + + S P +
Sbjct: 243 SQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTSSA 302
Query: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR-RYSPP 599
RG+ + SPS ++ R S T P+ + SP+ R R S
Sbjct: 303 RSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNK--GAMLENLSPTSRGRESRG 360
Query: 600 IQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659
Q SP S P R+SP R SS RS S SS+
Sbjct: 361 FQ---SPCLECAEVKKSSLVPSTARSSPMKGCSR-----------SSSYASTRSSSHSSR 406
Query: 660 HRKGSSPSRSTREARSPQPNKR-HSPSPRPRAPQTSSSPPPVRRGASSSPQ-RRQSPSPS 717
+ R T ++RS KR +S SP + SPP + SP R SPS
Sbjct: 407 SPNPRASPRYT-QSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRE 465
Query: 718 TRP--------------IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763
P RR R+ P + ++ SPS RR++S+R P P +
Sbjct: 466 RDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARK---RPIPYYRP 522
Query: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDK 823
P+ + S S + S + ++ S + S S R + + + +
Sbjct: 523 SPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSR 582
Query: 824 KHKKHKKHKKEKAVAAAAAAA 844
+ + + ++ + + ++A
Sbjct: 583 SRSRSRSRSRSRSQSRSYSSA 603
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/220 (31%), Positives = 91/220 (41%), Gaps = 30/220 (13%)
Query: 154 RDKEEKESSREKRERSRSPR------RRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTK- 206
R + + +S EKR SRSP +R S S R R SP S R P++ K
Sbjct: 415 RYTQSRSTSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKD 474
Query: 207 SRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSK 266
S+ ++ + P + PS EA + K P P P P ++
Sbjct: 475 SQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTS 534
Query: 267 KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
+R SRS S+SRSR+RS RRR R+R+ S S R PSP R R R
Sbjct: 535 SWYSSSSSRSASRSYSRSRSRSRS--------RRRSRTRTSSSSSSRSPSPGSRSRSRSR 586
Query: 327 TPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366
+ RSRS R R S S S + S SS+ R
Sbjct: 587 S------------RSRS---RSRSQSRSYSSADSYSSTRR 611
Score = 70.5 bits (171), Expect = 7e-12
Identities = 79/244 (32%), Positives = 95/244 (38%), Gaps = 65/244 (26%)
Query: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
S+R SRSP R S PR S KRS+SRSP + +KS SP P + ++
Sbjct: 397 STRSSSHSSRSPNPRAS----PRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP-PSRSSRS 451
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
PS PS +E P+ + K +++E+ R R R
Sbjct: 452 RR--SPSYSRYSPS----------------------RERDPKYSEKDSQQRERERARRRR 487
Query: 281 RSKSRSRTRSR-SPSHTRPRR--------------------------------RHRSRSR 307
RS S R R R SPSH RR RS SR
Sbjct: 488 RSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASR 547
Query: 308 SYSPRRRPSPRRRPSPRR--RTPPRRMPPPPRHRRSRSPVRRRRRS-SASLSGSSSSSSS 364
SYS R S RR S R + R P P RSRS R R RS S S S SS+ S S
Sbjct: 548 SYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYS 607
Query: 365 SRSR 368
S R
Sbjct: 608 STRR 611
Score = 63.9 bits (154), Expect = 6e-10
Identities = 58/176 (32%), Positives = 78/176 (44%), Gaps = 31/176 (17%)
Query: 153 KRDKEEKESSREKRERSRSPRRRKSRSPS-PRRRSSPVRRERKRSHSRSPRHRTKSRSPS 211
+RD + E ++RER R+ RRR+S SP RRR SP E +R S R
Sbjct: 465 ERDPKYSEKDSQQRERERARRRRRSYSPMRKRRRDSPSHLEARRITSARKR--------- 515
Query: 212 PAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEK 271
P P + P PS S S+S S ++ + + +
Sbjct: 516 PIPYYR------PSPSSSGSLSSTSSWYSSS--------------SSRSASRSYSRSRSR 555
Query: 272 EKTRPRSRSRSKSRSRTRSRSP-SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
++R RSR+R+ S S +RS SP S +R R R RSRSRS S R S S RR
Sbjct: 556 SRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSYSSADSYSSTRR 611
>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
Length = 1007
Score = 112 bits (281), Expect = 1e-24
Identities = 157/679 (23%), Positives = 267/679 (39%), Gaps = 119/679 (17%)
Query: 133 QRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRE 192
+ Q E E S K +E+ + +++ ++ + ++ + R K + + SS ++
Sbjct: 10 REQPEMEDANSEKSINEENGEVSEDQSQNKHSRHKKKKHKHRSKHKK---HKHSSEEDKD 66
Query: 193 RKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSV-QEATSTSDILKVPKPE 251
+K H +H+ K + +K P K+ + ++ ++ ++K
Sbjct: 67 KKHKH----KHKHKKHKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDN 122
Query: 252 PIPEPKEPSP--------EKNSKKEKE-KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRH 302
+ E K S E S++E E EK R +RS ++S S + +
Sbjct: 123 ELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKK 182
Query: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSS 362
RS+SRS + RT RHR + ++ + + ++
Sbjct: 183 RSKSRS---------------KERT---------RHRSDK----KKSKGGIEIVKEKTTR 214
Query: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422
S S+ R K P KR+ S + + SP+ RRR + +
Sbjct: 215 SKSKERKKSKSPSKRSKSQDQARKSKSPTL---RRRSQ--------------------EK 251
Query: 423 TRKSRVSVSPGRTSGKVT-KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
K+R SP K+ K K ++++SP ++ES GK + + +
Sbjct: 252 IGKAR---SPTDDKVKIEDKSKSKDRKKSPI---------INESRSRDRGKKSRSPVDLR 299
Query: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
+ R+++ S S + ++++P +S K+ G+ R SPSR SP++R
Sbjct: 300 GKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENR-SPSRRPGRSPKRRSLSPK 358
Query: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ 601
PR + RRS SP RR S +P RT +P R ++ S +RR P RR S P
Sbjct: 359 PRDKSRRSRSPLLNDRRSKQSKSP----SRTLSPGRRAKSRSLERKRREPERRRLSSP-- 412
Query: 602 RRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR 661
R RR S P R SP+ RR S SP ++ SP+ + RSP R
Sbjct: 413 RTRPRDDILSRRERSKDASPINRWSPT----RRRSRSPIRRRSRSPLRRSRSP-----RR 463
Query: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR-RGASSSPQRRQSPSPSTRP 720
+ SP R R RS +R S S R ++ S + +G+ S + + S S
Sbjct: 464 RSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDN 523
Query: 721 I----------------RRVSRTPEPKKIKKAASPSPQSV-----RRVSSSRSVSGSPEP 759
+ RR+ R +K K A S SV SS+R+ S SP+
Sbjct: 524 LEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSPDD 583
Query: 760 AAKKPPAPPSPVQSQSPST 778
++ A + ++ T
Sbjct: 584 ILERVAADVKEYERENVDT 602
Score = 108 bits (271), Expect = 2e-23
Identities = 126/461 (27%), Positives = 195/461 (42%), Gaps = 74/461 (16%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESS----REKRERSRSPRRRKSRSPSPR 183
K E+ +I +K + + ++ + + DK++ + +EK RS+S R+KS+SPS R
Sbjct: 170 KLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKR 229
Query: 184 RRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD 243
+S R+ S+SP R +S+ EK K + VK+++ S + S
Sbjct: 230 SKSQDQARK-----SKSPTLRRRSQ------EKIGKARSPTDDKVKIEDKSKSKDRKKSP 278
Query: 244 ILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
I+ + + K SP K K++ RSRSK R RS + +P +
Sbjct: 279 IINESRSRDRGK-KSRSPVDLRGKSKDR-------RSRSKERKSKRSETDKEKKPIKSPS 330
Query: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRH--RRSRSPVRRRRRSSASLSGSSSS 361
+ S R PS R SP+RR+ + P PR RRSRSP+ RRS S
Sbjct: 331 KDASSGKENRSPSRRPGRSPKRRS----LSPKPRDKSRRSRSPLLNDRRSK-------QS 379
Query: 362 SSSSRSRSPPKKPPKRTSSPPRK---TRRLSPSASPPR-----RRHRPSPPATPPPKTRH 413
S SR+ SP ++ R+ R+ RRLS + PR RR R + P R
Sbjct: 380 KSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDAS---PINRW 436
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR----KVELSESEEDK 469
SPT ++S R+ R S SP R S + +R S SP + R + L +
Sbjct: 437 SPTRRRS-RSPIRRRSRSPLRRS-------RSPRRRSRSPRRRDRGRRSRSRLRRRSRSR 488
Query: 470 GGKMAAADSVQQRRQYR-------RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRR 522
GG+ + S + +++ + Q+SSSD +E + + ++ +
Sbjct: 489 GGRRRRSRSKVKEDKFKGSLSEGMKVEQESSSDDNLEDFDVEEEDEEALIEQRRI----- 543
Query: 523 HSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSP 563
R A K E S SP + R RSPSP
Sbjct: 544 ---QRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSPSP 581
Score = 101 bits (252), Expect = 3e-21
Identities = 149/602 (24%), Positives = 226/602 (37%), Gaps = 84/602 (13%)
Query: 127 KKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRS 186
KK++ K R ++ S +EDKDK+ K + + + KR+ ++ SP+ R +
Sbjct: 44 KKKKHKHRSKHKKHKHS---SEEDKDKKHKHKHKHKKHKRKEIIDASDKEGMSPAKRTKL 100
Query: 187 SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILK 246
+ R A K E EL E V+ + + + +
Sbjct: 101 DDLALLEDLEKQR-------------ALIKAELDNELMEGKVQSGMGLILQGYESGSEEE 147
Query: 247 VPKPEPIPEPKEPSPEKNSKKEK-----EKEKTRPRSRSRSKSRSRTRS---RSPSHTRP 298
E S +S K K K T+ RS+SRSK R+R RS +S
Sbjct: 148 GEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEI 207
Query: 299 RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358
+ +RS+S ++ SP +R + + R+S+SP RRR
Sbjct: 208 VKEKTTRSKSKERKKSKSPSKRSKSQDQA-----------RKSKSPTLRRR--------- 247
Query: 359 SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP-----PPKTRH 413
S ++RSP K K R+ SP + R R R +P K R
Sbjct: 248 -SQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRR 306
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
S + ++ ++ ++ P ++ K + S P P++ LS DK +
Sbjct: 307 SRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKRRSLSPKPRDK-SRR 365
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP---SRSAS 530
+ + + RR ++QS S S + S + + K E RRR SP R
Sbjct: 366 SRSPLLNDRR-----SKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTRPRDDI 420
Query: 531 PSPRKRQKETSPRGR----RRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586
S R+R K+ SP R RRRS SP RRRS SP RR R+ PRRR+ SP
Sbjct: 421 LSRRERSKDASPINRWSPTRRRSRSP---IRRRSRSPL---RRSRS----PRRRSRSP-- 468
Query: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSS 646
RR RR ++RR +RR+ S K + S +S +Q SS
Sbjct: 469 -RRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGS--------LSEGMKVEQESS 519
Query: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706
+ + + R + Q K + P SSP R S
Sbjct: 520 SDDNLEDFDVEEEDEEALIEQRRIQRQAIVQKYKYLAEDSNMSVPSEPSSPQSSTRTRSP 579
Query: 707 SP 708
SP
Sbjct: 580 SP 581
Score = 84.7 bits (208), Expect = 3e-16
Identities = 130/579 (22%), Positives = 220/579 (37%), Gaps = 97/579 (16%)
Query: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSP 415
+G S S S KK + S +K + S + +H K +H
Sbjct: 28 NGEVSEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKH----------KHKHKK 77
Query: 416 TPQQSNRTRKSRVSVSPGRTS--GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG--- 470
++ + +SP + + + + EK+ + A EL E + G
Sbjct: 78 HKRKEIIDASDKEGMSPAKRTKLDDLALLEDLEKQRALIKAELDN--ELMEGKVQSGMGL 135
Query: 471 -------GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523
G + ++ R R + +SSS G +++ + K+ R R
Sbjct: 136 ILQGYESGSEEEGEIHEKARNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHR 195
Query: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS 583
S + + +++T+ + R S P++R +S A R++ +P RRR+
Sbjct: 196 SDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQA-----RKSKSPTLRRRSQE 250
Query: 584 PPPRRRSPSPRRY-----SPPIQRRYSP----SPPPKRRTASPPPPPKRRASPSPPPKRR 634
+ RSP+ + S R+ SP S R S P R S K R
Sbjct: 251 KIGKARSPTDDKVKIEDKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKS-----KDR 305
Query: 635 VSHSPPPKQRSSPVTKRRSPSLS-----SKHRKGSSPSRSTREARSPQPNKRHSPSPRPR 689
S S K + S K + P S S ++ SPSR R RSP KR S SP+PR
Sbjct: 306 RSRSKERKSKRSETDKEKKPIKSPSKDASSGKENRSPSR--RPGRSP---KRRSLSPKPR 360
Query: 690 APQTSSSPPPV---RRGASSSPQRRQSPS--PSTRPIRRVSRTPEPKKIKKAASPSPQSV 744
S P + R S SP R SP +R + R R PE +++ +SP +
Sbjct: 361 DKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRL---SSPRTRPR 417
Query: 745 RRVSSSRSVSGSPEPAAKKPPA---PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
+ S R S P + P SP++ +S S P+++++SP PR
Sbjct: 418 DDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRS-------PLRRSRSPRRRSRSPRR 470
Query: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEE 861
D+ G + + ++ + + ++ + K K++K + +
Sbjct: 471 RDR-GRRSRSRLRRRSRSRGGRRRRSRSKVKEDKFKGSLSEGM----------------- 512
Query: 862 PVAAPEPKKETESEAEDNLDDLE-KHLREKALRSMRKAQ 899
K E ES ++DNL+D + + E+AL R+ Q
Sbjct: 513 -------KVEQESSSDDNLEDFDVEEEDEEALIEQRRIQ 544
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 112 bits (280), Expect = 2e-24
Identities = 186/876 (21%), Positives = 316/876 (36%), Gaps = 134/876 (15%)
Query: 117 AGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRS-PRRR 175
AG+ + +L +EE +Q + + K E S K+E S P ++
Sbjct: 39 AGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAA---ESPSMHRKQELDSSHPPKQ 95
Query: 176 KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT-PELPEPSVKVKEP- 233
R P P R + P + + + + + RSPS K+ K+ +L E P
Sbjct: 96 SGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG 155
Query: 234 ---SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK--EKEKTRPRSRSRSKSRSRT 288
V ++ S ++ P + E S E+ +KK+K +KE+ +P + + +
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
Query: 289 RSRSPSHTRPRR---RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345
P P R + +S S ++ + +P P P + P+ ++ P+
Sbjct: 216 PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-PGTGKPIQGPTQTPQTDHAKLPL 274
Query: 346 RR-RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRP--- 401
+R R + S S P KPP + +P + P+ P + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-----PPAQQPGHEKSQPGPA 329
Query: 402 SPPATPPPKTRH--------SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
PPA P T+ P Q T+ + P + + T G+EK S P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT---GSEKPSSEQP 386
Query: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
PK + A QQ + QQ G S ++ P ++ V+
Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ----PGLQSPAKAPGPTKTPVQ 442
Query: 514 NGEVGRRRRHSPSRSASPSPRKRQK--ETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR 571
G+ P++ A P Q+ T P + PPP + P PA PP ++
Sbjct: 443 QPGPGK----IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQPGPAKPPPQQP 494
Query: 572 TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK-----RRTASPPPPPKRRAS 626
PP ++ S P + P P + SP Q+ S PP + + +A P P K A
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSP--QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH---- 682
S P + P + + + ++ PS K P +T E P K +
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP--KTICPLCNTTELLLHVPEKANFNTC 610
Query: 683 -------------SPSPR-------------------------PRAPQTSSSPPPVRRGA 704
+P+P P +PQ PV +
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS 670
Query: 705 S---SSPQRRQ-SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
+ SSPQ +Q SP P + +S+ PEPKK P P + ++ GSP
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK------PPP-----LVKQPTLHGSPSAK 719
Query: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP-----RNSDQEGGGKKKKKKK 815
AK+PP S P+ P+VP ++ K+P P + + K
Sbjct: 720 AKQPPEADS---LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 816 DKKHKKDKKHKKHKKHKKEKAVAAAAAAA-------VTPAAIAAATTTLAQEEPVAAPEP 868
D K + + K K +A + + V+P A + + ++ P P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 869 KKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904
+ES+ + +D ++K +E+ ++ K P +
Sbjct: 837 --SSESKGQKQVDPVQK--KEEPKKAQTKMSPKPDA 868
Score = 86.3 bits (212), Expect = 1e-16
Identities = 168/858 (19%), Positives = 304/858 (35%), Gaps = 183/858 (21%)
Query: 170 RSPRRRKSRSPSPRRRSSP--VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227
+SP + + +P ++ P + ++ S + ++ PS P + P+ P P+
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487
Query: 228 VKVKEPSVQEATSTSDILKVPKPEP---IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
K P Q ++ K P +P P P++P P K S ++ T+P S+ +
Sbjct: 488 ---KPPPQQPGSA-----KPPSQQPGSTKPPPQQPGPAKPSPQQPGS--TKPPSQQPGSA 537
Query: 285 RSRTRSRSPSHTRPRRRHR--SRSRSYSPRRRP--SPRRRPSPRRRTPPRRMPPPPRHRR 340
+ + SP+ ++ + S++ S P + P SP + P + P P
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR-----LSPSASPP 395
+ ++ + ++ S + +P K + +R L+P S P
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTR----KSRVSVSP---------------GRTS 436
+ + + +P T ++ SP PQQ++ + K +S +P G S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
K + + P+P +P SE+DK A D +Q + + SS S
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSV----PSEQDKAP--VADDKPKQPKMVKPTTDLVSSSS 771
Query: 497 GSSS--------------------SSEDERPKRSHVKNGEV-------GRRRRHSPSRSA 529
++ ++ +P +S GE R S S+
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 530 S-PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP--PP 586
S P P K ++ P + + SP P P + +PTPP R T P
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 587 RRRSPSPRRYSPPIQRRYSPS-----PPPKRRTASPP----------------------- 618
++SP P+ S RR+S + PK + +P
Sbjct: 892 PQQSPKPQEQS----RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 619 ----PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
P P ++ P P K+ + S PP + P + ++P +K S P + +E +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK----SIPVK--KETK 1001
Query: 675 SPQPNK---RHSPSPRPRAPQTSSSPPPVR--RGASSSPQR-------RQSPSP-STRPI 721
+P K + +P + +T PPP++ + ++ PQ+ +SP P ST P+
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 722 RRVSR---TPEPKKIKKAA------------SPSPQSVR-------RVSSSRSVSGSPEP 759
+ + +P +P+P + R++SG
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 760 AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKH 819
K PPAP P S P P P +S Q K +
Sbjct: 1122 IRKMPPAPSGPKAS--------------------PMPVPTESSSQ-------KTAVPPQV 1154
Query: 820 KKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDN 879
K KK ++ K + EK + ++ I TT ++E + K E +
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 880 LDDLEKHLREKALRSMRK 897
++ + E+ +RS K
Sbjct: 1215 PEEKKLIPEEEKIRSEEK 1232
Score = 71.2 bits (173), Expect = 4e-12
Identities = 157/814 (19%), Positives = 256/814 (31%), Gaps = 166/814 (20%)
Query: 79 NPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQ 138
NP+ + ++ LN + R G+L P+ S Q + P + Q Q
Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Query: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS 198
K + KQD S++P P++
Sbjct: 684 PKKDAAPKQD---------------------------LSKAPEPKK-------------- 702
Query: 199 RSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKE 258
P P K+ T PS K K+P EA S S KP P EP
Sbjct: 703 -------------PPPLVKQPTLH-GSPSAKAKQP--PEADSLS------KPAPPKEPSV 740
Query: 259 PSPEKNS----KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR 314
PS + + K K+ + +P + S S + T+ PS S+ +S + +
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS---------SKVQSQAEEKT 791
Query: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
P + S + P + PP + S + R ++ S SS S+ +
Sbjct: 792 TPPLKTDSAK----PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 375 PKRTSSPPRKTR-RLSPSA-SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
P + P+K + ++SP + P + P+PP P + PTPQQS + P
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK---------P 898
Query: 433 GRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492
S + + + G S + APK + E+ K A+ Q Q
Sbjct: 899 QEQSRRFSLNLG-----SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 493 SSDSGSSSSSEDERPKRSHVKNGE-VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551
+ + P S + + +P A P K++ + +
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE 1013
Query: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP--PIQRRYSPSPP 609
PT +R PPP + ++ P +SP P P + P
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 610 PKRRTAS---------------------------------------------PPPPPKRR 624
P T + PP P +
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 625 ASPSPPPKRRVSH--SPPP-----KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
ASP P P S + PP K++ V + K ++ S + + Q
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR-TPEPKKIKKA 736
+ + P P + P+ + S +P+ + TPE KK+
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEK--KLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE 1251
Query: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS----------PAVPV 786
A S ++ +S E + AP + + + P T P
Sbjct: 1252 AKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD 1311
Query: 787 KKAKSPTPSPSPP--RNSDQEGGGKKKKKKKDKK 818
K K+ P PP DQ GK+K +K+D K
Sbjct: 1312 KTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345
Score = 62.4 bits (150), Expect = 2e-09
Identities = 141/713 (19%), Positives = 243/713 (34%), Gaps = 56/713 (7%)
Query: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKR----ERSRSPRRR 175
P + K+EE K + + L K E+K +EEK S EK+ E+ +P +
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK 1246
Query: 176 KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSR-SPSPAPEKKEKTPELPE-PSVKVKEP 233
K + + + +S + + + R +P E K+ ++ PS +
Sbjct: 1247 KLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 234 SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP 293
++ +T I + P+P +P + P K K EKE +K+ S + KS +
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE-KTEKEDDKSDTSSSQQPKS-----PQGL 1360
Query: 294 SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
S T S S P P+ + + P + + S
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSIL 1420
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA----SPPRRRHRPSPPATPPP 409
S+ + S ++ P + KT+ LS + S +
Sbjct: 1421 EAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFK 1480
Query: 410 KTRHSPTPQQSNRTRKSR-VSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED 468
K P + KS V R + + +E SP P K R+ + S D
Sbjct: 1481 KDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK-RRTSVGSSSSD 1539
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE--RPKRSHVKNGEVGRRRRHSPS 526
+ + + S ++ R+Q + S+D +S S +DE R + + + +++ +
Sbjct: 1540 EYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKG 1599
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP---------SPAPPPRRRRTPTPPP 577
+ + + R R R+ S S RR +P + R T +
Sbjct: 1600 KGKITAGKHR------RLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQES 1653
Query: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA-SPPPPPKRRASPSPPPKRRVS 636
+ R + I +YS K+ + P S + P+ R
Sbjct: 1654 EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSR 1713
Query: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK-RHSP-SPRPRAPQTS 694
+S T SP+ S + S S S ++ S Q K RH P P + S
Sbjct: 1714 GEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDS 1773
Query: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS 754
S +R ++ + R I + R KK KK RR
Sbjct: 1774 SEEEELREEEELLKEQEKQ-----REIEQQQRKSSSKKSKKDKDELRAQRRR-------- 1820
Query: 755 GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKA-KSPTPSPSPPRNSDQEG 806
K PP+ SP++ SP+ A +++ +S SP SD EG
Sbjct: 1821 ----ERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 49.3 bits (116), Expect = 2e-05
Identities = 79/336 (23%), Positives = 123/336 (36%), Gaps = 44/336 (13%)
Query: 505 ERPKRSHVKNGEV-GRRRRHSPSRSASPSPRKRQKETSPRGRRRR---SPSPPPTRRRRS 560
E+ ++ +GE G+ + S S SPS + P R S PPP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413
Query: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRR--SPSPRRYSPPI-----------QRRYSPS 607
P P PPP P PPP P+ P+++ SP + P+ R +
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473
Query: 608 PPPKRRTASPPP-PPKRRASPS------PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
P + T +PPP PPK + PS P + +P P P T ++ + K
Sbjct: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Query: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS------PQRRQSP 714
S S T + K SP+ P +P ++ S P + + + P +P
Sbjct: 2534 TGLSLTSSMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTP 2592
Query: 715 SPSTRPIRRVSRTPEPKKIKKAASPSP--------QSVRRVSSSRS---VSGSPEPAAKK 763
+ S+ + ++ P K S P +V SS +SG+ + +
Sbjct: 2593 TDSSAS-QAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT 2651
Query: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAK-SPTPSPSP 798
P PS Q+ S V K + S T S +P
Sbjct: 2652 PVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP 2687
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184
EL KE+ KQR+IEQ++ +K K K+DK+E + R +RER ++P + SP
Sbjct: 1784 ELLKEQEKQREIEQQQ----RKSSSKKSKKDKDELRAQR-RRERPKTP----PSNLSPIE 1834
Query: 185 RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL-PEPSVKVKE 232
+SP E +++ HR+ SP+ E + E+ PE ++V++
Sbjct: 1835 DASPT-EELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQK 1882
Score = 41.2 bits (95), Expect = 0.004
Identities = 110/561 (19%), Positives = 190/561 (33%), Gaps = 111/561 (19%)
Query: 113 QENIAGIPSAFLE-LKKEEIKQRQI--EQEKLASMKKQDEDKDKRDKEEKESSREKRERS 169
Q + G+PS + L KE+ K + EQ + K D+ + ++K EKE + S
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS--PAPEK----------- 216
+ P+ + S + +S + PS P EK
Sbjct: 1352 QQPKSPQGLSDT--------------GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSF 1397
Query: 217 -KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE--KNSKKEKEKEK 273
+E +P P K++ + + + L K E +P E SPE K+ +K + +
Sbjct: 1398 SQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSE 1457
Query: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR----PSPRRRP--SPRRRT 327
T + S + + R + + ++ S+ + + + RR P S +
Sbjct: 1458 TLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
Query: 328 PPRRMPPPPRHRR-----SRSPVRRRRRSSAS-------------------LSGSS---- 359
P P R RR S S ++ S S SGS
Sbjct: 1518 ESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEF 1577
Query: 360 --------SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA--SPPRRRH----RPSPPA 405
SSS+ S+ + K K T+ R+ R S ++ RRH
Sbjct: 1578 IRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAF 1637
Query: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES 465
P+ ++ T Q + + V G T + + S +K L
Sbjct: 1638 DESPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFD 1694
Query: 466 EEDKGGKMAAADSVQQRRQ-------YRRQNQQSSSDSGSSSSSEDERPKRSHVK-NGEV 517
EE + + DS + R + + +S + SS ED SH K +
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 518 GRRRRHSPSRSASPS----------------PRKRQKETSPRGRRRRSPSPPPTRRRRSP 561
R+ RH P P+ ++++K+ ++R+S S + ++
Sbjct: 1755 QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSS---KKSKKDK 1811
Query: 562 SPAPPPRRRRTPTPPPRRRTP 582
RRR P PP +P
Sbjct: 1812 DELRAQRRRERPKTPPSNLSP 1832
Score = 40.0 bits (92), Expect = 0.010
Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 18/148 (12%)
Query: 127 KKEEIKQRQIEQEK-----LASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPS 181
KK E KQ++ + + L +++ E+++ R++EE +EK +R ++RKS S
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEK-QREIEQQQRKSSSKK 1806
Query: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
++ +R +R+R ++P + E+ + E+ E + S E +
Sbjct: 1807 SKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEE----LHRSSCSEYS-- 1860
Query: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEK 269
P E PE E SPEK + +K
Sbjct: 1861 ------PSIESDPEGFEISPEKIIEVQK 1882
Score = 38.5 bits (88), Expect = 0.029
Identities = 135/750 (18%), Positives = 252/750 (33%), Gaps = 118/750 (15%)
Query: 209 SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD--ILKVPKPEPIPEPKEPSPEKNSK 266
SP P P + P VK+ + QE + ++ IL+ K E P + K
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQK 1194
Query: 267 KEKEK-EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR-RRPSPR 324
+E+ K EK + + K + P + R + + ++P+P ++ P
Sbjct: 1195 QEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK---KPLLEEKKPTPEDKKLLPE 1251
Query: 325 RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
+T P +H +S V + + L G + + + P K S P+
Sbjct: 1252 AKT---SAPEEQKHDLLKSQV---QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQS 1305
Query: 385 TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS-----------PG 433
+ + + +P PP T P + KS S S G
Sbjct: 1306 LPK-EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG 1364
Query: 434 RTSGKVTKHKG-------TEKRE-----------------SPSPAPKPRKVELSESE--- 466
+S ++ G T++++ SPS K LS E
Sbjct: 1365 YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 467 ----EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR-- 520
++K K V + ++ QS S++ + SE+E +K + R+
Sbjct: 1425 STLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE------IKESQEERKDT 1478
Query: 521 -RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
++ S S K + E RR P S + P R+RRT
Sbjct: 1479 FKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSS 1538
Query: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSP 639
+ S + I+++ + + S R + +S S
Sbjct: 1539 DEYKQEDSQGSGEEEDF---IRKQIIEMSADEDASGSEDDEFIRN------QLKEISSST 1589
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH---------SPSPRPRA 690
+++ TK + + KHR+ + S ++ + + + + H SP + R
Sbjct: 1590 ESQKKEE--TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE 1647
Query: 691 PQTSSSPPPVRRGAS----------SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
++ S V G +S + + S++ + EP+ ++ + S
Sbjct: 1648 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS 1707
Query: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS--------- 791
P+ R S S+ S + P P+ V S ++ SP+ ++K
Sbjct: 1708 PEDRSRGEGSSSLHAS----SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPH 1763
Query: 792 ----PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTP 847
PT S +E K+++K ++ ++ ++ KK KK+K A P
Sbjct: 1764 GPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 848 AAIAAATTTLAQEEPVAAPEPKKETESEAE 877
T + P+ P +E AE
Sbjct: 1824 ------KTPPSNLSPIEDASPTEELRQAAE 1847
Score = 38.1 bits (87), Expect = 0.037
Identities = 91/465 (19%), Positives = 165/465 (35%), Gaps = 65/465 (13%)
Query: 109 LLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER 168
L + + I A +E +++ + +++ + +D++K + E E + + E
Sbjct: 1409 LAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEI 1468
Query: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHS--------RSPRHRTKSRSPS---PAPEKK 217
S RK ++ P ++ K R P + S S P P++K
Sbjct: 1469 KESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSD-----ILKVPKPEPIPEPKEPSPEKNSKKE---- 268
+T S + K+ Q + D I+++ E ++ +N KE
Sbjct: 1529 RRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSS 1588
Query: 269 ---KEKEKTRPRSR-SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP--RRRPS 322
++KE+T+ + + + K R TR S S R S SP + R +
Sbjct: 1589 TESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRET 1648
Query: 323 PRRRTPPRRMPPPPRHRRSRS-PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
+ + + RR ++ + S S +S P + T SP
Sbjct: 1649 KSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSP 1708
Query: 382 PRKTRRLSPSASPPRRRHRPS-PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
++R S+ H S P T P T S + S+ SP G+
Sbjct: 1709 EDRSRGEGSSS-----LHASSFTPGTSP--TSVSSLDEDSDS--------SPSHKKGESK 1753
Query: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
+ + + R P P + SE EE + + + + ++ +R+ +Q S S
Sbjct: 1754 QQR--KARHRPHGPLLPTIEDSSEEEE-----LREEEELLKEQEKQREIEQQQRKSSSKK 1806
Query: 501 SSEDERPKRSHVKNGEVGRRRRH--------SPSRSASPSPRKRQ 537
S +D+ R+ RRR SP ASP+ RQ
Sbjct: 1807 SKKDKDELRAQ-------RRRERPKTPPSNLSPIEDASPTEELRQ 1844
Score = 35.4 bits (80), Expect = 0.24
Identities = 64/264 (24%), Positives = 95/264 (35%), Gaps = 44/264 (16%)
Query: 125 ELKKEEIKQRQIEQ------EKLASMKKQDEDKDKRDKEEKESSREKRER---SRSPRRR 175
ELK E K ++ E+ L K + + DK ESS++K
Sbjct: 1642 ELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEM 1701
Query: 176 KSRSPSPRRRSSPVRRERKRS-HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
+S + SP RS R E S H+ S T S S E + +P + K +
Sbjct: 1702 ESLTDSPEDRS---RGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ--- 1755
Query: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS 294
++A +P E E +E E+ KE+EK+ R + + KS S+ +
Sbjct: 1756 -RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ--REIEQQQRKSSSKKSKKDKD 1812
Query: 295 HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-----PPRHRRSRSPVRRRR 349
R +RR R RP +TPP + P P R + +
Sbjct: 1813 ELRAQRR----------RERP----------KTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 350 RSSASLSGSSSSSSSSRSRSPPKK 373
RSS S S S P+K
Sbjct: 1853 RSSCSEYSPSIESDPEGFEISPEK 1876
Score = 35.0 bits (79), Expect = 0.32
Identities = 41/163 (25%), Positives = 58/163 (35%), Gaps = 31/163 (19%)
Query: 281 RSKSRSRTRSRSPSHT----RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP 336
+ K S+ S SPS + +PR RS S S + P P P P PP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 337 RHRRSRSPVRRRRR---------------------SSASLSGSSSSSSSSRSRSPPKKPP 375
+ + +++ ++A L + + + +PP PP
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 376 KRTSSPPRK--TRRLSPSASPPRRRHRPSPPATPPPKTRHSPT 416
K +S P T R PS P P P P T PT
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPP----IAPKPVIPQLPTTTQKPT 2527
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR------RLSPSASPPRR 397
P++ + ++ SG + S+ P P SS P K R L SA PP
Sbjct: 2351 PMKEQLSTTYFTSGETFGQEKPASQLPSGSPS--VSSLPAKPRPFFRSSSLDISAQPPPP 2408
Query: 398 RHRPSPPATPPPKTRHSPTP 417
P PP PPP P P
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLP 2428
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 112 bits (280), Expect = 2e-24
Identities = 186/876 (21%), Positives = 316/876 (36%), Gaps = 134/876 (15%)
Query: 117 AGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRS-PRRR 175
AG+ + +L +EE +Q + + K E S K+E S P ++
Sbjct: 39 AGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAA---ESPSMHRKQELDSSHPPKQ 95
Query: 176 KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT-PELPEPSVKVKEP- 233
R P P R + P + + + + + RSPS K+ K+ +L E P
Sbjct: 96 SGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPG 155
Query: 234 ---SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK--EKEKTRPRSRSRSKSRSRT 288
V ++ S ++ P + E S E+ +KK+K +KE+ +P + + +
Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQP 215
Query: 289 RSRSPSHTRPRR---RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPV 345
P P R + +S S ++ + +P P P + P+ ++ P+
Sbjct: 216 PKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQP-PGTGKPIQGPTQTPQTDHAKLPL 274
Query: 346 RR-RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRP--- 401
+R R + S S P KPP + +P + P+ P + +P
Sbjct: 275 QRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK-----PPAQQPGHEKSQPGPA 329
Query: 402 SPPATPPPKTRH--------SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453
PPA P T+ P Q T+ + P + + T G+EK S P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQT---GSEKPSSEQP 386
Query: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
PK + A QQ + QQ G S ++ P ++ V+
Sbjct: 387 GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ----PGLQSPAKAPGPTKTPVQ 442
Query: 514 NGEVGRRRRHSPSRSASPSPRKRQK--ETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRR 571
G+ P++ A P Q+ T P + PPP + P PA PP ++
Sbjct: 443 QPGPGK----IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQPGPAKPPPQQP 494
Query: 572 TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK-----RRTASPPPPPKRRAS 626
PP ++ S P + P P + SP Q+ S PP + + +A P P K A
Sbjct: 495 GSAKPPSQQPGSTKPPPQQPGPAKPSP--QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH---- 682
S P + P + + + ++ PS K P +T E P K +
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLP--KTICPLCNTTELLLHVPEKANFNTC 610
Query: 683 -------------SPSPR-------------------------PRAPQTSSSPPPVRRGA 704
+P+P P +PQ PV +
Sbjct: 611 TECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS 670
Query: 705 S---SSPQRRQ-SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
+ SSPQ +Q SP P + +S+ PEPKK P P + ++ GSP
Sbjct: 671 AVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKK------PPP-----LVKQPTLHGSPSAK 719
Query: 761 AKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP-----RNSDQEGGGKKKKKKK 815
AK+PP S P+ P+VP ++ K+P P + + K
Sbjct: 720 AKQPPEADS---LSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776
Query: 816 DKKHKKDKKHKKHKKHKKEKAVAAAAAAA-------VTPAAIAAATTTLAQEEPVAAPEP 868
D K + + K K +A + + V+P A + + ++ P P
Sbjct: 777 DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 869 KKETESEAEDNLDDLEKHLREKALRSMRKAQVSPQS 904
+ES+ + +D ++K +E+ ++ K P +
Sbjct: 837 --SSESKGQKQVDPVQK--KEEPKKAQTKMSPKPDA 868
Score = 86.3 bits (212), Expect = 1e-16
Identities = 168/858 (19%), Positives = 304/858 (35%), Gaps = 183/858 (21%)
Query: 170 RSPRRRKSRSPSPRRRSSP--VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227
+SP + + +P ++ P + ++ S + ++ PS P + P+ P P+
Sbjct: 428 QSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487
Query: 228 VKVKEPSVQEATSTSDILKVPKPEP---IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
K P Q ++ K P +P P P++P P K S ++ T+P S+ +
Sbjct: 488 ---KPPPQQPGSA-----KPPSQQPGSTKPPPQQPGPAKPSPQQPGS--TKPPSQQPGSA 537
Query: 285 RSRTRSRSPSHTRPRRRHR--SRSRSYSPRRRP--SPRRRPSPRRRTPPRRMPPPPRHRR 340
+ + SP+ ++ + S++ S P + P SP + P + P P
Sbjct: 538 KPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL 597
Query: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR-----LSPSASPP 395
+ ++ + ++ S + +P K + +R L+P S P
Sbjct: 598 LLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP 657
Query: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTR----KSRVSVSP---------------GRTS 436
+ + + +P T ++ SP PQQ++ + K +S +P G S
Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717
Query: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
K + + P+P +P SE+DK A D +Q + + SS S
Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSV----PSEQDKAP--VADDKPKQPKMVKPTTDLVSSSS 771
Query: 497 GSSS--------------------SSEDERPKRSHVKNGEV-------GRRRRHSPSRSA 529
++ ++ +P +S GE R S S+
Sbjct: 772 ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKII 831
Query: 530 S-PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP--PP 586
S P P K ++ P + + SP P P + +PTPP R T P
Sbjct: 832 SHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPT 891
Query: 587 RRRSPSPRRYSPPIQRRYSPS-----PPPKRRTASPP----------------------- 618
++SP P+ S RR+S + PK + +P
Sbjct: 892 PQQSPKPQEQS----RRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947
Query: 619 ----PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
P P ++ P P K+ + S PP + P + ++P +K S P + +E +
Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAK----SIPVK--KETK 1001
Query: 675 SPQPNK---RHSPSPRPRAPQTSSSPPPVR--RGASSSPQR-------RQSPSP-STRPI 721
+P K + +P + +T PPP++ + ++ PQ+ +SP P ST P+
Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL 1061
Query: 722 RRVSR---TPEPKKIKKAA------------SPSPQSVR-------RVSSSRSVSGSPEP 759
+ + +P +P+P + R++SG
Sbjct: 1062 CKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGD 1121
Query: 760 AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKH 819
K PPAP P S P P P +S Q K +
Sbjct: 1122 IRKMPPAPSGPKAS--------------------PMPVPTESSSQ-------KTAVPPQV 1154
Query: 820 KKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDN 879
K KK ++ K + EK + ++ I TT ++E + K E +
Sbjct: 1155 KLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEKKPL 1214
Query: 880 LDDLEKHLREKALRSMRK 897
++ + E+ +RS K
Sbjct: 1215 PEEKKLIPEEEKIRSEEK 1232
Score = 71.2 bits (173), Expect = 4e-12
Identities = 157/814 (19%), Positives = 256/814 (31%), Gaps = 166/814 (20%)
Query: 79 NPDSKMMQINLTGFLNGKNAREFMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQ 138
NP+ + ++ LN + R G+L P+ S Q + P + Q Q
Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS 683
Query: 139 EKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS 198
K + KQD S++P P++
Sbjct: 684 PKKDAAPKQD---------------------------LSKAPEPKK-------------- 702
Query: 199 RSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKE 258
P P K+ T PS K K+P EA S S KP P EP
Sbjct: 703 -------------PPPLVKQPTLH-GSPSAKAKQP--PEADSLS------KPAPPKEPSV 740
Query: 259 PSPEKNS----KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR 314
PS + + K K+ + +P + S S + T+ PS S+ +S + +
Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS---------SKVQSQAEEKT 791
Query: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
P + S + P + PP + S + R ++ S SS S+ +
Sbjct: 792 TPPLKTDSAK----PSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 375 PKRTSSPPRKTR-RLSPSA-SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
P + P+K + ++SP + P + P+PP P + PTPQQS + P
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPK---------P 898
Query: 433 GRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492
S + + + G S + APK + E+ K A+ Q Q
Sbjct: 899 QEQSRRFSLNLG-----SITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 493 SSDSGSSSSSEDERPKRSHVKNGE-VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551
+ + P S + + +P A P K++ + +
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAE 1013
Query: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSP--PIQRRYSPSPP 609
PT +R PPP + ++ P +SP P P + P
Sbjct: 1014 QAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDP 1073
Query: 610 PKRRTAS---------------------------------------------PPPPPKRR 624
P T + PP P +
Sbjct: 1074 PNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPSGPK 1133
Query: 625 ASPSPPPKRRVSH--SPPP-----KQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
ASP P P S + PP K++ V + K ++ S + + Q
Sbjct: 1134 ASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQ 1193
Query: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR-TPEPKKIKKA 736
+ + P P + P+ + S +P+ + TPE KK+
Sbjct: 1194 KQEESKLEKDKASALQEKKPLPEEK--KLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPE 1251
Query: 737 ASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWS----------PAVPV 786
A S ++ +S E + AP + + + P T P
Sbjct: 1252 AKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDD 1311
Query: 787 KKAKSPTPSPSPP--RNSDQEGGGKKKKKKKDKK 818
K K+ P PP DQ GK+K +K+D K
Sbjct: 1312 KTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDK 1345
Score = 62.4 bits (150), Expect = 2e-09
Identities = 141/713 (19%), Positives = 243/713 (34%), Gaps = 56/713 (7%)
Query: 120 PSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKR----ERSRSPRRR 175
P + K+EE K + + L K E+K +EEK S EK+ E+ +P +
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDK 1246
Query: 176 KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSR-SPSPAPEKKEKTPELPE-PSVKVKEP 233
K + + + +S + + + R +P E K+ ++ PS +
Sbjct: 1247 KLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSL 1306
Query: 234 SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP 293
++ +T I + P+P +P + P K K EKE +K+ S + KS +
Sbjct: 1307 PKEDDKTTKTIKEQPQPPCTAKPDQVEPGKE-KTEKEDDKSDTSSSQQPKS-----PQGL 1360
Query: 294 SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
S T S S P P+ + + P + + S
Sbjct: 1361 SDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSIL 1420
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA----SPPRRRHRPSPPATPPP 409
S+ + S ++ P + KT+ LS + S +
Sbjct: 1421 EAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQEERKDTFK 1480
Query: 410 KTRHSPTPQQSNRTRKSR-VSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED 468
K P + KS V R + + +E SP P K R+ + S D
Sbjct: 1481 KDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK-RRTSVGSSSSD 1539
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE--RPKRSHVKNGEVGRRRRHSPS 526
+ + + S ++ R+Q + S+D +S S +DE R + + + +++ +
Sbjct: 1540 EYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQKKEETKG 1599
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP---------SPAPPPRRRRTPTPPP 577
+ + + R R R+ S S RR +P + R T +
Sbjct: 1600 KGKITAGKHR------RLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQES 1653
Query: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA-SPPPPPKRRASPSPPPKRRVS 636
+ R + I +YS K+ + P S + P+ R
Sbjct: 1654 EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSPEDRSR 1713
Query: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNK-RHSP-SPRPRAPQTS 694
+S T SP+ S + S S S ++ S Q K RH P P + S
Sbjct: 1714 GEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPHGPLLPTIEDS 1773
Query: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS 754
S +R ++ + R I + R KK KK RR
Sbjct: 1774 SEEEELREEEELLKEQEKQ-----REIEQQQRKSSSKKSKKDKDELRAQRRR-------- 1820
Query: 755 GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKA-KSPTPSPSPPRNSDQEG 806
K PP+ SP++ SP+ A +++ +S SP SD EG
Sbjct: 1821 ----ERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSIESDPEG 1869
Score = 49.3 bits (116), Expect = 2e-05
Identities = 79/336 (23%), Positives = 123/336 (36%), Gaps = 44/336 (13%)
Query: 505 ERPKRSHVKNGEV-GRRRRHSPSRSASPSPRKRQKETSPRGRRRR---SPSPPPTRRRRS 560
E+ ++ +GE G+ + S S SPS + P R S PPP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPP 2413
Query: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRR--SPSPRRYSPPI-----------QRRYSPS 607
P P PPP P PPP P+ P+++ SP + P+ R +
Sbjct: 2414 PPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGL 2473
Query: 608 PPPKRRTASPPP-PPKRRASPS------PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660
P + T +PPP PPK + PS P + +P P P T ++ + K
Sbjct: 2474 PVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKP 2533
Query: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS------PQRRQSP 714
S S T + K SP+ P +P ++ S P + + + P +P
Sbjct: 2534 TGLSLTSSMTLNLVTSADYKLPSPT-SPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTP 2592
Query: 715 SPSTRPIRRVSRTPEPKKIKKAASPSP--------QSVRRVSSSRS---VSGSPEPAAKK 763
+ S+ + ++ P K S P +V SS +SG+ + +
Sbjct: 2593 TDSSAS-QAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSAT 2651
Query: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAK-SPTPSPSP 798
P PS Q+ S V K + S T S +P
Sbjct: 2652 PVTAPSSFQAAPTSVTQFLTTEVSKTEVSATRSTAP 2687
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/109 (32%), Positives = 59/109 (54%), Gaps = 11/109 (10%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184
EL KE+ KQR+IEQ++ +K K K+DK+E + R +RER ++P + SP
Sbjct: 1784 ELLKEQEKQREIEQQQ----RKSSSKKSKKDKDELRAQR-RRERPKTP----PSNLSPIE 1834
Query: 185 RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPEL-PEPSVKVKE 232
+SP E +++ HR+ SP+ E + E+ PE ++V++
Sbjct: 1835 DASPT-EELRQAAEMEELHRSSCSEYSPSIESDPEGFEISPEKIIEVQK 1882
Score = 41.2 bits (95), Expect = 0.004
Identities = 110/561 (19%), Positives = 190/561 (33%), Gaps = 111/561 (19%)
Query: 113 QENIAGIPSAFLE-LKKEEIKQRQI--EQEKLASMKKQDEDKDKRDKEEKESSREKRERS 169
Q + G+PS + L KE+ K + EQ + K D+ + ++K EKE + S
Sbjct: 1292 QTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSS 1351
Query: 170 RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPS--PAPEK----------- 216
+ P+ + S + +S + PS P EK
Sbjct: 1352 QQPKSPQGLSDT--------------GYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSF 1397
Query: 217 -KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPE--KNSKKEKEKEK 273
+E +P P K++ + + + L K E +P E SPE K+ +K + +
Sbjct: 1398 SQESSPSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSE 1457
Query: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR----PSPRRRP--SPRRRT 327
T + S + + R + + ++ S+ + + + RR P S +
Sbjct: 1458 TLEITISEEEIKESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESS 1517
Query: 328 PPRRMPPPPRHRR-----SRSPVRRRRRSSAS-------------------LSGSS---- 359
P P R RR S S ++ S S SGS
Sbjct: 1518 ESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEF 1577
Query: 360 --------SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA--SPPRRRH----RPSPPA 405
SSS+ S+ + K K T+ R+ R S ++ RRH
Sbjct: 1578 IRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAF 1637
Query: 406 TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSES 465
P+ ++ T Q + + V G T + + S +K L
Sbjct: 1638 DESPELKYRETKSQES---EELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFD 1694
Query: 466 EEDKGGKMAAADSVQQRRQ-------YRRQNQQSSSDSGSSSSSEDERPKRSHVK-NGEV 517
EE + + DS + R + + +S + SS ED SH K +
Sbjct: 1695 EEPELEMESLTDSPEDRSRGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQ 1754
Query: 518 GRRRRHSPSRSASPS----------------PRKRQKETSPRGRRRRSPSPPPTRRRRSP 561
R+ RH P P+ ++++K+ ++R+S S + ++
Sbjct: 1755 QRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSS---KKSKKDK 1811
Query: 562 SPAPPPRRRRTPTPPPRRRTP 582
RRR P PP +P
Sbjct: 1812 DELRAQRRRERPKTPPSNLSP 1832
Score = 40.0 bits (92), Expect = 0.010
Identities = 36/148 (24%), Positives = 67/148 (45%), Gaps = 18/148 (12%)
Query: 127 KKEEIKQRQIEQEK-----LASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPS 181
KK E KQ++ + + L +++ E+++ R++EE +EK +R ++RKS S
Sbjct: 1748 KKGESKQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEK-QREIEQQQRKSSSKK 1806
Query: 182 PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATST 241
++ +R +R+R ++P + E+ + E+ E + S E +
Sbjct: 1807 SKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEE----LHRSSCSEYS-- 1860
Query: 242 SDILKVPKPEPIPEPKEPSPEKNSKKEK 269
P E PE E SPEK + +K
Sbjct: 1861 ------PSIESDPEGFEISPEKIIEVQK 1882
Score = 38.5 bits (88), Expect = 0.029
Identities = 135/750 (18%), Positives = 252/750 (33%), Gaps = 118/750 (15%)
Query: 209 SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD--ILKVPKPEPIPEPKEPSPEKNSK 266
SP P P + P VK+ + QE + ++ IL+ K E P + K
Sbjct: 1135 SPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQK 1194
Query: 267 KEKEK-EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR-RRPSPR 324
+E+ K EK + + K + P + R + + ++P+P ++ P
Sbjct: 1195 QEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEK---KPLLEEKKPTPEDKKLLPE 1251
Query: 325 RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
+T P +H +S V + + L G + + + P K S P+
Sbjct: 1252 AKT---SAPEEQKHDLLKSQV---QIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQS 1305
Query: 385 TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVS-----------PG 433
+ + + +P PP T P + KS S S G
Sbjct: 1306 LPK-EDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTG 1364
Query: 434 RTSGKVTKHKG-------TEKRE-----------------SPSPAPKPRKVELSESE--- 466
+S ++ G T++++ SPS K LS E
Sbjct: 1365 YSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPSSPSDLAKLESTVLSILEAQA 1424
Query: 467 ----EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR-- 520
++K K V + ++ QS S++ + SE+E +K + R+
Sbjct: 1425 STLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEE------IKESQEERKDT 1478
Query: 521 -RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRR 579
++ S S K + E RR P S + P R+RRT
Sbjct: 1479 FKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTSVGSSSS 1538
Query: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSP 639
+ S + I+++ + + S R + +S S
Sbjct: 1539 DEYKQEDSQGSGEEEDF---IRKQIIEMSADEDASGSEDDEFIRN------QLKEISSST 1589
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH---------SPSPRPRA 690
+++ TK + + KHR+ + S ++ + + + + H SP + R
Sbjct: 1590 ESQKKEE--TKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRE 1647
Query: 691 PQTSSSPPPVRRGAS----------SSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS 740
++ S V G +S + + S++ + EP+ ++ + S
Sbjct: 1648 TKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDS 1707
Query: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS--------- 791
P+ R S S+ S + P P+ V S ++ SP+ ++K
Sbjct: 1708 PEDRSRGEGSSSLHAS----SFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQRKARHRPH 1763
Query: 792 ----PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTP 847
PT S +E K+++K ++ ++ ++ KK KK+K A P
Sbjct: 1764 GPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRAQRRRERP 1823
Query: 848 AAIAAATTTLAQEEPVAAPEPKKETESEAE 877
T + P+ P +E AE
Sbjct: 1824 ------KTPPSNLSPIEDASPTEELRQAAE 1847
Score = 38.1 bits (87), Expect = 0.037
Identities = 91/465 (19%), Positives = 165/465 (35%), Gaps = 65/465 (13%)
Query: 109 LLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER 168
L + + I A +E +++ + +++ + +D++K + E E + + E
Sbjct: 1409 LAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEI 1468
Query: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHS--------RSPRHRTKSRSPS---PAPEKK 217
S RK ++ P ++ K R P + S S P P++K
Sbjct: 1469 KESQEERKDTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRK 1528
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSD-----ILKVPKPEPIPEPKEPSPEKNSKKE---- 268
+T S + K+ Q + D I+++ E ++ +N KE
Sbjct: 1529 RRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSS 1588
Query: 269 ---KEKEKTRPRSR-SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP--RRRPS 322
++KE+T+ + + + K R TR S S R S SP + R +
Sbjct: 1589 TESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEAFDESPELKYRET 1648
Query: 323 PRRRTPPRRMPPPPRHRRSRS-PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
+ + + RR ++ + S S +S P + T SP
Sbjct: 1649 KSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEMESLTDSP 1708
Query: 382 PRKTRRLSPSASPPRRRHRPS-PPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
++R S+ H S P T P T S + S+ SP G+
Sbjct: 1709 EDRSRGEGSSS-----LHASSFTPGTSP--TSVSSLDEDSDS--------SPSHKKGESK 1753
Query: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
+ + + R P P + SE EE + + + + ++ +R+ +Q S S
Sbjct: 1754 QQR--KARHRPHGPLLPTIEDSSEEEE-----LREEEELLKEQEKQREIEQQQRKSSSKK 1806
Query: 501 SSEDERPKRSHVKNGEVGRRRRH--------SPSRSASPSPRKRQ 537
S +D+ R+ RRR SP ASP+ RQ
Sbjct: 1807 SKKDKDELRAQ-------RRRERPKTPPSNLSPIEDASPTEELRQ 1844
Score = 35.4 bits (80), Expect = 0.24
Identities = 64/264 (24%), Positives = 95/264 (35%), Gaps = 44/264 (16%)
Query: 125 ELKKEEIKQRQIEQ------EKLASMKKQDEDKDKRDKEEKESSREKRER---SRSPRRR 175
ELK E K ++ E+ L K + + DK ESS++K
Sbjct: 1642 ELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEEPELEM 1701
Query: 176 KSRSPSPRRRSSPVRRERKRS-HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPS 234
+S + SP RS R E S H+ S T S S E + +P + K +
Sbjct: 1702 ESLTDSPEDRS---RGEGSSSLHASSFTPGTSPTSVSSLDEDSDSSPSHKKGESKQQ--- 1755
Query: 235 VQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS 294
++A +P E E +E E+ KE+EK+ R + + KS S+ +
Sbjct: 1756 -RKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQ--REIEQQQRKSSSKKSKKDKD 1812
Query: 295 HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-----PPRHRRSRSPVRRRR 349
R +RR R RP +TPP + P P R + +
Sbjct: 1813 ELRAQRR----------RERP----------KTPPSNLSPIEDASPTEELRQAAEMEELH 1852
Query: 350 RSSASLSGSSSSSSSSRSRSPPKK 373
RSS S S S P+K
Sbjct: 1853 RSSCSEYSPSIESDPEGFEISPEK 1876
Score = 35.0 bits (79), Expect = 0.32
Identities = 41/163 (25%), Positives = 58/163 (35%), Gaps = 31/163 (19%)
Query: 281 RSKSRSRTRSRSPSHT----RPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP 336
+ K S+ S SPS + +PR RS S S + P P P P PP PP P
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 337 RHRRSRSPVRRRRR---------------------SSASLSGSSSSSSSSRSRSPPKKPP 375
+ + +++ ++A L + + + +PP PP
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 376 KRTSSPPRK--TRRLSPSASPPRRRHRPSPPATPPPKTRHSPT 416
K +S P T R PS P P P P T PT
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPP----IAPKPVIPQLPTTTQKPT 2527
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/80 (30%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR------RLSPSASPPRR 397
P++ + ++ SG + S+ P P SS P K R L SA PP
Sbjct: 2351 PMKEQLSTTYFTSGETFGQEKPASQLPSGSPS--VSSLPAKPRPFFRSSSLDISAQPPPP 2408
Query: 398 RHRPSPPATPPPKTRHSPTP 417
P PP PPP P P
Sbjct: 2409 PPPPPPPPPPPPPPPPPPLP 2428
Score = 31.6 bits (70), Expect = 3.5
Identities = 37/171 (21%), Positives = 65/171 (38%), Gaps = 39/171 (22%)
Query: 197 HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP 256
H +S ++ +SP P+ K P+PS ++ P+++++ S+
Sbjct: 4834 HGKSHSSQSSQQSPKPSVIKSRSHGIFPDPSKDMQVPTIEKSHSS--------------- 4878
Query: 257 KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316
P K+S + RS S+S+S+T S + +H + + + + R
Sbjct: 4879 --PGSSKSS------SEGHLRSHGPSRSQSKT-SVTQTHLEDAGAAIAAAEAAVQQLRIQ 4929
Query: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS 367
P + PP HR + S V S+ SG S S S S
Sbjct: 4930 PTK---------------PPNHRPAESSVSTGSSGSSFGSGYSVDSEGSSS 4965
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 111 bits (278), Expect = 3e-24
Identities = 135/543 (24%), Positives = 207/543 (38%), Gaps = 69/543 (12%)
Query: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSG----- 357
R ++++ + R P+ R R P PPPP +P R +A G
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPV-----TPAALRVLGAAGAVGRKPLA 59
Query: 358 --SSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP---PPKTR 412
+ ++ S P+ P RTS PP R +PP + P P ++P TR
Sbjct: 60 ERAGGIGGATIPESAPRAGPTRTSRPPASGRG---ERAPPAKNTSPGPVSSPGRASGTTR 116
Query: 413 HSPTPQQSNR------TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA-PKPRKVELSES 465
P Q+ R + + + +P R++ + T P+P P P S +
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS---GPTPGTPSPAMARRSRA 173
Query: 466 EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSP 525
+ G A S + R + SS S S++ +R G + R S
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233
Query: 526 SRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP 585
S SA+P + S RG R +P+ P + + PP+ TPP + P+
Sbjct: 234 SSSATPLSSPARSGPSARGTPR-APAHPSQPKPKGLQALRPPQ----VTPPRKDAAPALG 288
Query: 586 PRRRSP--SPRRYSPPIQRRYSPSPPPKRRTASPPP--PPKRRASPSPPPKRRVSHSPPP 641
P SP +P +PP SPS PP +T PP PP + + P + +HS P
Sbjct: 289 PLSSSPLATPSPSAPP-----SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343
Query: 642 KQRSSPVTKRRS--------PSLSSKHRKGSSPSRSTREARSPQ-PNK----------RH 682
SP+ P L + +SP S SPQ PN
Sbjct: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403
Query: 683 SPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742
PSP +AP + + PPV S++P + PS + P++ P + +A+P PQ
Sbjct: 404 PPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461
Query: 743 SVRRVSSSRSVSGSP----EPAAKKPP--APPSPVQSQSPSTNWSPAVPVKKAKSPTPSP 796
+ +++ P PA PP A PSP S +SP+ + + TP P
Sbjct: 462 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521
Query: 797 SPP 799
P
Sbjct: 522 QAP 524
Score = 93.6 bits (231), Expect = 7e-19
Identities = 152/652 (23%), Positives = 232/652 (35%), Gaps = 111/652 (17%)
Query: 159 KESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
K + KR + RR + P+P S + R RS T+ P PAP +
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-------RSRAAGTEVGLPRPAPSARP 189
Query: 219 KTP-ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
+ P E P SV S E ++T EPSP + RP
Sbjct: 190 RPPTEGPRKSVS----SASEHSTT----------------EPSPAARRRPSAGGGLQRPA 229
Query: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
SRS S S T SP+ + P R R+ ++ + +P + P + TPPR+ P
Sbjct: 230 SRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287
Query: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTS----------------SP 381
S SP+ S ++ S+ S SPP PP + + SP
Sbjct: 288 GPLSSSPL--ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345
Query: 382 PRKTRRLSPSASPPRR----------RHRPSPPATPPPKTRHSPTPQQSN--RTRKSRVS 429
P LSP A+PP + + PSPPA+PP +P+PQ N +
Sbjct: 346 P-----LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 430 VSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQN 489
SP + ++P P V S + + AA +Q +
Sbjct: 401 FSP----------PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV-----PPS 445
Query: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549
+S S++ + P ++ + +P A+P + + P ++
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQA 503
Query: 550 PSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP 609
P P SP PPP+ P + PSPP +PRR P+P
Sbjct: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---------PPTPG 554
Query: 610 PKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS--KHRKGSSPS 667
P + P P PPP R P S P S S +S + +G
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSR-----SPSSTLSGPDLAGHSSSATSTPEELRGYDSG 609
Query: 668 RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP-----IR 722
A SP P+ + + P A +PP RGA +P P+T P +
Sbjct: 610 PEGGAAASPPPDAELA-ACHPAAWSRGPAPPLAFRGAPGAP---LPWPPATGPGSADGLC 665
Query: 723 RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
+ T P ++A+P+P ++ S + G A + SP Q++
Sbjct: 666 TIYETEGP----ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713
Score = 90.5 bits (223), Expect = 6e-18
Identities = 153/637 (24%), Positives = 224/637 (35%), Gaps = 75/637 (11%)
Query: 200 SPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK-E 258
+PR S PA + E+ P K S +S +P P+ +
Sbjct: 74 APRAGPTRTSRPPASGRGERAPP-------AKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126
Query: 259 PSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR-RPSP 317
S E+ + K E + RS + +R T +P P RSR+ RP+P
Sbjct: 127 ISAEETVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 318 RRRPSPRRRTPPRRMPPPPRHRRSR-SPVRRRRRSS-------ASLSGSSSS---SSSSR 366
RP P P + + H + SP RRR S+ AS S SSS+ SS +R
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR 245
Query: 367 S----RSPPKKPPKRTSSPPRKTRRLSP-SASPPRRRHRP-------SPPATPPPKTRHS 414
S R P+ P + P+ + L P +PPR+ P SP ATP P S
Sbjct: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305
Query: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
P+ S +T S + P + + T + + S P P L+ +A
Sbjct: 306 PSAPPSLQTLPSPPATPPSQAT---TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
+ +S ++ + P V + SP A SP
Sbjct: 363 LPPLQAP------PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP- 415
Query: 535 KRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594
+ P PS P P PP P P P PP +P +
Sbjct: 416 ---PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472
Query: 595 RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654
PP Q + + PP + SPP +A SP +S P ++ PV +P
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL--AAP 530
Query: 655 SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP 714
L +SP+ R P+P P TS S P + + P P
Sbjct: 531 LLQVPPSPPASPTLQA---------PRRPPTP---GPDTSVSGPRLTLALAPGP----PP 574
Query: 715 SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
PS P +S P+ +A+ +P+ +R S PE A P P + + +
Sbjct: 575 PPSRSPSSTLS-GPDLAGHSSSATSTPEELRGYDS------GPEGGAAASPPPDAELAAC 627
Query: 775 SPSTNWS--PAVPVKKAKSP-TPSPSPPRNSDQEGGG 808
P+ WS PA P+ +P P P PP G
Sbjct: 628 HPAA-WSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663
>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
Length = 1984
Score = 110 bits (276), Expect = 5e-24
Identities = 170/668 (25%), Positives = 244/668 (36%), Gaps = 98/668 (14%)
Query: 155 DKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERK-----RSHSRSP-------- 201
+ + + + EKR + R+ + S+ P +R + +R+ RK R+ SP
Sbjct: 1264 ESDSESTQNEKRAKVRTKKTSDSKYPM-KRITKRLRKHRKFYTNSRTTIESPSRELAAHL 1322
Query: 202 -RHRTKSRSPSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTSDILKVP---KPEPIPEP 256
R R + S A K++ K P P+ +++ S++ A T+ + KP P
Sbjct: 1323 RRKRIGATQTSTASLKRQPKKPSQPK-FMQLLFQSLKRAFQTAHRVIASVGRKPVDGTRP 1381
Query: 257 KEPSPEKNS-KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR----------RRHRSR 305
KN K+ ++ P S R K + + + S + R +
Sbjct: 1382 DNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQEDILWGGTVQCRSAQQP 1441
Query: 306 SRSYSPRRRPSPRRRPSPRRRTP-----------PRRMPPPPRHRRSRSPVRRRRRSSAS 354
R+YS +P P R P P P R RS+ R SS
Sbjct: 1442 RRAYS--FQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETSSQE 1499
Query: 355 LSGSSSSSS--SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
S+ + +R R P P KRT K + + P +R P P +TR
Sbjct: 1500 SKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNHPSF-YRERTPRGPSERTR 1558
Query: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGK 472
H+P+ R R + S +H +R SP+ RK S SE
Sbjct: 1559 HNPS------WRNHRSPSERSQRSSLERRHHSPSQRSHCSPS---RKNHSSPSE------ 1603
Query: 473 MAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS 532
+ R ++N S + S SE S + +RR HSPS + S
Sbjct: 1604 -------RSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRS 1656
Query: 533 PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR-RRSP 591
P +R +S RR RSPS R R PS R+ P RR SP R R P
Sbjct: 1657 PSERSHRSSSE-RRHRSPSQ---RSHRGPS-------ERSHCSPSERRHRSPSQRSHRGP 1705
Query: 592 SPRRYSPPIQRRYSPSPPPKRRTASPPP----PPKRRASPSPPPKRRVSHSPPPKQRSSP 647
S RR+ P +R S P +R SP P R+ SP +R HSP + SP
Sbjct: 1706 SERRHHSPSKR--SHRSPARRSHRSPSERSHHSPSERSHHSPSERRH--HSPSERSHCSP 1761
Query: 648 VTKRRSPSLSSKHRKGSSP---SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
+ +HR S S S + SP HSPS R R S + +
Sbjct: 1762 SERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERS 1821
Query: 705 SSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP------SPQSVRRVSSSRSVSGSPE 758
SP R+S R RR+S K SP SP R SSS SP
Sbjct: 1822 HRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPS 1881
Query: 759 PAAKKPPA 766
+ + P+
Sbjct: 1882 ERSHRSPS 1889
Score = 109 bits (273), Expect = 1e-23
Identities = 150/593 (25%), Positives = 218/593 (36%), Gaps = 101/593 (17%)
Query: 162 SREKRERSRSPRRRKSRSPSPRRRSS-----------PVRRERKRSHSRSPRHRTKSRSP 210
S ++ R+ S + R R P P S P+R +K S SRS ++ ++ +
Sbjct: 1437 SAQQPRRAYSFQPRPLRLPKPTDSQSGIAFQTASVGQPLRTVQKDSSSRSKKNFYRNETS 1496
Query: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKE 270
S +++ L P +V+ + +P SP K +
Sbjct: 1497 S------QESKNLSTPGTRVQA----------------RGRILPG----SPVKRTWHRHL 1530
Query: 271 KEKTRPRSRSRSKSRSRTRSRSPS----HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
K+K + + R PS H R HRS S +R RR SP +R
Sbjct: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSER--SQRSSLERRHHSPSQR 1588
Query: 327 T---PPRRMPPPPRHRRSRSPVRRRR-----RSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
+ P R+ P R RSP +R RS SLS S S RS P + +R
Sbjct: 1589 SHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQ--RRH 1646
Query: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT--- 435
SP ++ R SP R HR S + RH Q+S+R R SP
Sbjct: 1647 HSPSERSHR-----SPSERSHRSSS------ERRHRSPSQRSHRGPSERSHCSPSERRHR 1695
Query: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
S H+G +R SP+ + + S + + S + + S S+
Sbjct: 1696 SPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSE 1755
Query: 496 SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPT 555
S SE S ++ RR HSPS + SP +R SP RRR SP
Sbjct: 1756 RSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHH-SPSERRRHSPLERSR 1814
Query: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR-RYSPSPPPKRRT 614
S P RR + R S R SPS + + P++R R SPS
Sbjct: 1815 HSLLERSHRSPSERRSHRSFERSHRRIS--ERSHSPSEKSHLSPLERSRCSPS------- 1865
Query: 615 ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSR-STREA 673
+RR S + HSP + SP R+ + HR +R S E
Sbjct: 1866 -------ERRGHSS---SGKTCHSPSERSHRSPSGMRQGRTSERSHRSSCERTRHSPSEM 1915
Query: 674 RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSR 726
R +P+ R+ SP R+ ++ P++ G S P RP +SR
Sbjct: 1916 RPGRPSGRNHCSPSERSRRS-----PLKEGLKYS-------FPGERPSHSLSR 1956
Score = 107 bits (267), Expect = 5e-23
Identities = 198/807 (24%), Positives = 305/807 (37%), Gaps = 126/807 (15%)
Query: 108 LLLSAQENIAGIPSAFLELKKE-EIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK- 165
LL+ Q ++ P E++ + R ++ +++ +++D +R + K
Sbjct: 1144 LLIYPQLHLVRTPEGHGEVRLHLGFRLRIGKRSQISKYRERDRPVIRRSPISPSQRKAKI 1203
Query: 166 -RERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
+ S+SP P + +PV+ +R P K+++ +P + + LP
Sbjct: 1204 YTQASKSPTSTIDLQSGPSQSPAPVQVYIRRGQRSRPDLVEKTKTRAPGHYEFTQVHNLP 1263
Query: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
E S E+T KV K+ S K K K R R + +
Sbjct: 1264 E--------SDSESTQNEKRAKV-------RTKKTSDSKYPMKRITK---RLRKHRKFYT 1305
Query: 285 RSRTRSRSPS-----HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR---RTPPRRMPPPP 336
SRT SPS H R +R +++ + S +R+P +P + ++ R
Sbjct: 1306 NSRTTIESPSRELAAHLRRKRIGATQTSTASLKRQPKKPSQPKFMQLLFQSLKRAFQTAH 1365
Query: 337 RHRRS--RSPVRRRRRSSASLSGSSSSSSSSRSRSPPK--KPPKRTS---SPPRKTRRLS 389
R S R PV R + S + ++R P K KR++ +P T +
Sbjct: 1366 RVIASVGRKPVDGTRPDNLWASKNYYPKQNARDYCLPSSIKRDKRSADKLTPAGSTIKQE 1425
Query: 390 P----------SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV 439
SA PRR + P PK PT QS ++ P RT K
Sbjct: 1426 DILWGGTVQCRSAQQPRRAYSFQPRPLRLPK----PTDSQSGIAFQTASVGQPLRTVQKD 1481
Query: 440 TKHKG--------TEKRESPSPAPKPRKVE-----LSESEEDKGGKMAAADSVQQRRQ-- 484
+ + T +ES + + +V+ L S + D + +
Sbjct: 1482 SSSRSKKNFYRNETSSQESKNLSTPGTRVQARGRILPGSPVKRTWHRHLKDKLTHKEHNH 1541
Query: 485 ---YRRQNQQSSSD------SGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535
YR + + S+ S + S ER +RS ++ RR HSPS+ + SP
Sbjct: 1542 PSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLE------RRHHSPSQRSHCSP-S 1594
Query: 536 RQKETSPRGRRRRSPS-----PPPTRRRRSPSP----APPPRRRRTPTPPPRRRTPSPPP 586
R+ +SP R RSPS PP R S S +P R R P+ +RR SP
Sbjct: 1595 RKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPS---QRRHHSPSE 1651
Query: 587 R-RRSPSPRRYSPPIQRRY-SPSP-----PPKRRTASPPPPPKRRASPSP----PPKRRV 635
R RSPS R + +RR+ SPS P +R S P +R SPS P R
Sbjct: 1652 RSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCS--PSERRHRSPSQRSHRGPSERR 1709
Query: 636 SHSPPPKQRSSPVTK-RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA--PQ 692
HSP + SP + RSPS S H S S R SP + HSPS R +
Sbjct: 1710 HHSPSKRSHRSPARRSHRSPSERSHH------SPSERSHHSPSERRHHSPSERSHCSPSE 1763
Query: 693 TSSSPPPVRRGASSSPQRRQSP------SPSTR----PIRRVSRTPEPKKIKKAASPSPQ 742
S P RR S S +R SP SPS R P R +P + S +
Sbjct: 1764 RSHCSPSERRHRSPSERRHHSPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHR 1823
Query: 743 SVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ-SQSPSTNWSPAVPVKKAKSPTPSPSPPRN 801
S S RS S +++ +P S + SP+ + S SP
Sbjct: 1824 SPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSER 1883
Query: 802 SDQEGGGKKKKKKKDKKHKKDKKHKKH 828
S + G ++ + ++ H+ + +H
Sbjct: 1884 SHRSPSGMRQGRTSERSHRSSCERTRH 1910
Score = 107 bits (266), Expect = 7e-23
Identities = 138/474 (29%), Positives = 179/474 (37%), Gaps = 77/474 (16%)
Query: 151 KDKRDKEEKESSREKRERS-RSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRS 209
KDK +E RER+ R P R +PS R SP R ++ S R RH + S+
Sbjct: 1531 KDKLTHKEHNHPSFYRERTPRGPSERTRHNPSWRNHRSPSERSQRSSLER--RHHSPSQR 1588
Query: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPE----PIPEPKEPSPEKNS 265
+P +K + PS + S S PE + E SP + S
Sbjct: 1589 SHCSPSRKNHS-----------SPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRS 1637
Query: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR--PSPRRRPSP 323
+ + + S +S S RS S R R + R S R PS RR SP
Sbjct: 1638 HRGPSQRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSP 1697
Query: 324 RRRT---PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
+R+ P R P R RSP RR RS + S S S S S P +R
Sbjct: 1698 SQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHS------PSERRHH 1751
Query: 381 PPRKTRRLSPS----ASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTS 436
P + SPS SP RRHR +P + HSP+ + + SP S
Sbjct: 1752 SPSERSHCSPSERSHCSPSERRHR-----SPSERRHHSPSEKSHH---------SPSERS 1797
Query: 437 GKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDS 496
H +R SP + R L S + + R +RR +++S S S
Sbjct: 1798 -----HHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSF---ERSHRRISERSHSPS 1849
Query: 497 GSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR-----RSPS 551
S S ER + S RR HS S SP +R SP G R+ RS
Sbjct: 1850 EKSHLSPLERSRCS------PSERRGHSSSGKTCHSPSER-SHRSPSGMRQGRTSERSHR 1902
Query: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR-RRSPSPR--RYSPPIQR 602
R R SPS P R P R SP R RRSP +YS P +R
Sbjct: 1903 SSCERTRHSPSEMRPGR-------PSGRNHCSPSERSRRSPLKEGLKYSFPGER 1949
Score = 85.9 bits (211), Expect = 2e-16
Identities = 96/317 (30%), Positives = 122/317 (38%), Gaps = 46/317 (14%)
Query: 150 DKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRS 209
++ R E+ R RSP +R R PS R SP R + RS R ++ R
Sbjct: 1651 ERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710
Query: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSP-EKNSKKE 268
SP+ ++ ++P + PS + S S E SP E+
Sbjct: 1711 HSPS-KRSHRSPARRSH----RSPSERSHHSPS------------ERSHHSPSERRHHSP 1753
Query: 269 KEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS--YSPRRR----PSPRRRPS 322
E+ P RS S S R RSPS RRH S S +SP R PS RRR S
Sbjct: 1754 SERSHCSPSERSHC-SPSERRHRSPS----ERRHHSPSEKSHHSPSERSHHSPSERRRHS 1808
Query: 323 PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK----PPKRT 378
P R+ + R RSP RR S S S RS SP +K P +R+
Sbjct: 1809 PLERSRHSLL-----ERSHRSPSERRSHRSFE---RSHRRISERSHSPSEKSHLSPLERS 1860
Query: 379 SSPPRKTRRLSPSA----SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGR 434
P + R S S SP R HR SP +T RTR S + PGR
Sbjct: 1861 RCSPSERRGHSSSGKTCHSPSERSHR-SPSGMRQGRTSERSHRSSCERTRHSPSEMRPGR 1919
Query: 435 TSGKVTKHKGTEKRESP 451
SG+ R SP
Sbjct: 1920 PSGRNHCSPSERSRRSP 1936
Score = 80.5 bits (197), Expect = 7e-15
Identities = 83/286 (29%), Positives = 108/286 (37%), Gaps = 26/286 (9%)
Query: 146 KQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT 205
+ + R E+ R RSP +R R PS RR SP +R + RS R +
Sbjct: 1671 RSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPS 1730
Query: 206 KSRSPSPAPEKKEKTPELPEPSVKVK---EPSVQEATSTSDIL-KVPKPEPIPEPKEPSP 261
+ SP+ E S + PS + S S+ + P P E S
Sbjct: 1731 ERSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSH 1790
Query: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321
S++ R R +SR RS RR HRS RS+ RR
Sbjct: 1791 HSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSH---------RRI 1841
Query: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS-RSPPKKPPKRTSS 380
S R +P + P R SP RR SS SG + S S RS RSP RTS
Sbjct: 1842 SERSHSPSEKSHLSPLERSRCSPSERRGHSS---SGKTCHSPSERSHRSPSGMRQGRTS- 1897
Query: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
S +S R RH PS P R+ +P S R+R+S
Sbjct: 1898 ------ERSHRSSCERTRHSPSEMRPGRPSGRNHCSP--SERSRRS 1935
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 109 bits (272), Expect = 1e-23
Identities = 76/259 (29%), Positives = 105/259 (40%), Gaps = 11/259 (4%)
Query: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP--PRRRSPSPRRYSPPIQRRYSP 606
+PSPPPT P P T T PP TPSPP P SPPI +
Sbjct: 1405 TPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS---TT 1461
Query: 607 SPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP--VTKRRSPSLSSKHRKGS 664
+ PP T SPP + +P P + +PPP SP T P+ ++ +
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521
Query: 665 SPSRSTREARSPQPNKRHS-PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRR 723
+PS T +P P S P+ P P TS++ P S P +P P+T P
Sbjct: 1522 TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPP 1581
Query: 724 VSRTPEPKKIKKAASP---SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW 780
+ TP P I P +P +++ + +P P P PP+ + P+T
Sbjct: 1582 TTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1641
Query: 781 SPAVPVKKAKSPTPSPSPP 799
SP PT +PSPP
Sbjct: 1642 SPPPTTTTTPPPTTTPSPP 1660
Score = 97.8 bits (242), Expect = 4e-20
Identities = 119/489 (24%), Positives = 173/489 (35%), Gaps = 118/489 (24%)
Query: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370
P PSP P+ PP P PP + P + + S +++++ +
Sbjct: 1402 PTTTPSPP--PTSTTTLPPTTTPSPPTTTTTTPP------PTTTPSPPITTTTTPPPTTT 1453
Query: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA----TPPPKTRHSP------TPQQS 420
P P T++PP T P+ +P PSPP TPPP T SP TP S
Sbjct: 1454 PSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS 1513
Query: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQ 480
T + SP T+ T + +P P
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTL----------------- 1556
Query: 481 QRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKET 540
+++ S +++ P + SP + +PSP T
Sbjct: 1557 ---------PPTTTPSPPPTTTTTPPPTTT------------PSPPTTTTPSPPTITTTT 1595
Query: 541 SPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPI 600
P +PSPP T + PPP T TP P TP PP + P
Sbjct: 1596 PP---PTTTPSPPTT-----TTTTPPP----TTTPSPPTTTPITPPTSTTTLP------- 1636
Query: 601 QRRYSPSPPPKRRTASPP---PPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLS 657
+PSPPP T PP P P +PSPP + PP SSP+T
Sbjct: 1637 -PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTT-PPPTTTPSSPIT-------- 1686
Query: 658 SKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPS 717
++PS T +P SP+ P +P T+++ P S P +PSP+
Sbjct: 1687 ------TTPSPPTTTMTTP------SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT 1734
Query: 718 TRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPS 777
T TP P P ++S ++ +P P + PP SP + +P+
Sbjct: 1735 T--------TPSPPTTTMTTLPP------TTTSSPLTTTPLPPSITPPT-FSPFSTTTPT 1779
Query: 778 TNWSPAVPV 786
T P VP+
Sbjct: 1780 T---PCVPL 1785
Score = 95.1 bits (235), Expect = 3e-19
Identities = 83/308 (26%), Positives = 122/308 (39%), Gaps = 39/308 (12%)
Query: 524 SPSRSASPSPRKRQKE---TSPRGRRRRSPSPPPTRRRRSPSPAP--PPRRRRT----PT 574
+P + +PSP T+P + +PPPT P+ P PP T T
Sbjct: 1463 TPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTT 1522
Query: 575 PPPRRRTPSPPPRRRSPSPRRYSP--------PIQRRYSPSPPPKRRTASPP---PPPKR 623
P P T + PP +PSP +P + +PSPPP T PP P P
Sbjct: 1523 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1582
Query: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRS--PSLSSKHRKGSSPSRSTREARSPQPNKR 681
+PSPP + +PPP SP T + P ++ ++P + P
Sbjct: 1583 TTTPSPPTI--TTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTT 1640
Query: 682 HSPSPRPRA--PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
SP P P T++ PP S +P P+T P ++ TP P +P
Sbjct: 1641 PSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMT-TP 1699
Query: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPP-------SPVQSQSPSTNWSPAVPVKKAKSP 792
SP + + S ++ + P++ P+PP SP + SP T +P SP
Sbjct: 1700 SPTT----TPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP 1755
Query: 793 -TPSPSPP 799
T +P PP
Sbjct: 1756 LTTTPLPP 1763
Score = 94.0 bits (232), Expect = 6e-19
Identities = 91/317 (28%), Positives = 126/317 (39%), Gaps = 48/317 (15%)
Query: 524 SPSRSASPSPRKRQKETSPRGRRRRSP-----SPPPTRRRRSPSPAPPPRRRRTPTPPPR 578
+P + +PSP T P P +PPPT P+ P P T TP P
Sbjct: 1431 TPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSP---PTTTPSPP 1487
Query: 579 RRTPSPPPRRRSPSPRRYSP--------PIQRRYSPSP-------PPKRRTASPP----- 618
T + PP +PSP +P + +PSP PP T SPP
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 619 -PPPKR-----RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS--LSSKHRKGSSPSRST 670
PP +PSPPP + PP S P T SP ++ ++PS T
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTT-PPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606
Query: 671 REARSPQPNKRHS-PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729
+P P S P+ P P TS++ P S P +P P+T P + TP
Sbjct: 1607 TTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666
Query: 730 PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA----PPSPV-QSQSPSTNWSPAV 784
P I +P P + SS + + SP P+ P SP+ + +PS+ +P+
Sbjct: 1667 P-PITTTTTPPPTTT--PSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP 1723
Query: 785 P--VKKAKSPTPSPSPP 799
P SPT +PSPP
Sbjct: 1724 PPTTMTTPSPTTTPSPP 1740
Score = 76.3 bits (186), Expect = 1e-13
Identities = 116/644 (18%), Positives = 230/644 (35%), Gaps = 58/644 (9%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3764 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3823
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3824 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3884 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3941
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3942 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 4002 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 4050
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 4051 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 4098
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 4099 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4153
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPR-----PRAPQTSSS 696
+P+ + ++P + +T +P P + P P A T+S+
Sbjct: 4154 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSN 4213
Query: 697 PPPVRRGASSSPQ-RRQSPSPSTRPIRRVSRTPEPKKIKKAASPS-PQSVRRVSSSRSVS 754
PPP SS+PQ R + SP T +S P ++ A PS P + S ++S
Sbjct: 4214 PPP----ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269
Query: 755 GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
P P P + S S V + TP+P+P
Sbjct: 4270 PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP 4313
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 1970 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2029
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2030 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2089
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2090 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2147
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2148 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2207
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2208 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2256
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2257 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2304
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2305 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 2360 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2419
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2534
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2190
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2191 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2250
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2251 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2308
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2309 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2368
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2417
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2418 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2465
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2466 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 2521 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2580
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2695
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2282
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2343 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2400
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2401 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2509
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2510 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2557
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2558 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 2613 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2672
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2733 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2787
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2444 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2503
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2504 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2561
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2562 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2670
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2671 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2718
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2719 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2833
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2948
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2535
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2536 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2596 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2653
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2654 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2762
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2763 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2810
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2811 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 2866 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 2925
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3040
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2696
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2757 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2814
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2815 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 2923
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 2924 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 2971
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 2972 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3027 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3147 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3201
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2789 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 2849 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 2906
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 2907 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3015
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3016 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3063
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3064 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3178
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3293
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2949
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 2950 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3067
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3068 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3127
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3176
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3177 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3224
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3225 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3280 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3339
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3454
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3041
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3042 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3102 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3159
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3160 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3268
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3269 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3316
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3317 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3372 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3431
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3491
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3546
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3202
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3203 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3262
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3263 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3320
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3321 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3380
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3429
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3430 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3477
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3478 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3532
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3533 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3592
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3652
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3653 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3707
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3294
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3295 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3355 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3412
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3413 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3521
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3522 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3569
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3570 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3625 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3684
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3744
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3745 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3799
Score = 71.6 bits (174), Expect = 3e-12
Identities = 108/660 (16%), Positives = 237/660 (35%), Gaps = 75/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3455
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3456 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3516 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3573
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3574 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 3682
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 3683 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 3730
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 3731 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 3786 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 3845
Query: 702 RGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSS 750
G + + +P+P+ + + TP +P+P + ++++
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3905
Query: 751 RSVSGSPEPAAKKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+V+ +P P + P P+P +Q+P+T P+ + TP+P+P
Sbjct: 3906 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 3960
Score = 71.2 bits (173), Expect = 4e-12
Identities = 112/645 (17%), Positives = 232/645 (35%), Gaps = 62/645 (9%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3741 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3800
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3801 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3861 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 3918
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 3919 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3978
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 4027
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + +P+ P + +P P P +TPT P T + P +P+P
Sbjct: 4028 -------TPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP---TPTP 4075
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK 650
P + +P T +P P P +P+ P V+ +P P +P T
Sbjct: 4076 TGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130
Query: 651 --------RRSPSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701
+P+ + ++P + +T +P P +P+ P T+ +P P
Sbjct: 4131 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 4190
Query: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761
G + P S T PI ++ + P + S +PQ+ R S+S ++ S +
Sbjct: 4191 TGTQTGPPTHTS----TAPIAELTTSNPPPE-----SSTPQTSR--STSSPLTESTTLLS 4239
Query: 762 KKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEG 806
PPA ++ S + +P P + T SP P + G
Sbjct: 4240 TLPPA----IEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG 4280
Score = 70.9 bits (172), Expect = 5e-12
Identities = 118/660 (17%), Positives = 232/660 (35%), Gaps = 76/660 (11%)
Query: 179 SPSPRRRSSPVRRERKRSHSRSPRHR-TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237
+P+P +P + + +P T +++P+ P T + P+
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855
Query: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT---RPRSRSRSKSRSRTRSRSPS 294
T+T+ + P P P + T P + + + + T + +P+
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3915
Query: 295 HTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
T+ P + + + +P P+ + P+ T + P P +++P ++
Sbjct: 3916 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3975
Query: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
+++ + + + + + P + P T +P+ +P +P TP P
Sbjct: 3976 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--TPTPTGTQ 4033
Query: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473
+PT T + +P T T T +P+P P + +
Sbjct: 4034 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4093
Query: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
+ +++ + + + + + P + + + + + +P+P
Sbjct: 4094 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-----------TTTTTVTPTP 4142
Query: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
+P G + + +P T +P+P P + T TP T +P P +P+
Sbjct: 4143 -------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP---TPTG 4192
Query: 594 RRYSPPIQRRYSPSPPPKRRTASPPP----PPKRRASPSP-----------PPKRRVSHS 638
+ PP S +P + T++PPP P R++ SP PP ++ +
Sbjct: 4193 TQTGPPTHT--STAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTST 4250
Query: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698
PP ++P T S H PS +T +P R +SS+P
Sbjct: 4251 APPSTPTAPTT------TSGGHTLSPPPSTTTSPPGTP---------TRGTTTGSSSAPT 4295
Query: 699 PVRRGASSSPQRRQSPSPSTRP--IRRVSRTPEPKKIKKAA-------SPSPQSVRRVSS 749
P +++ +P+P + P IR P P + +P +
Sbjct: 4296 PSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYG 4355
Query: 750 SR------SVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
S+S + E P+ PSP + S ST +P+ P PTP PP D
Sbjct: 4356 DTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTP-TPSKPSSTPSKPTPGTKPPECPD 4414
Score = 69.7 bits (169), Expect = 1e-11
Identities = 132/682 (19%), Positives = 227/682 (33%), Gaps = 102/682 (14%)
Query: 201 PRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA-----TSTSDILKVPKPEPIPE 255
P T + P+ P TP P S P+ + T+T P P
Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585
Query: 256 PKEPS------PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY 309
P P+ P + T P + + T P+ T + S
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645
Query: 310 SPRRRPSPRRRPSPRRRTPPRRMPP------PPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
+ P P PSP T P PP PP SP+ + + S ++
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPS--PPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTT 1703
Query: 364 SSRSRSPPKKPPKRTSSP-PRKTRRLSPSA----SPPRRRHRPSPPA-TPPPKTRHSPTP 417
+ S P T++P P T +PS SPP PP T P T P
Sbjct: 1704 TPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPP 1763
Query: 418 QQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAAD 477
+ T + +P + G P+ EL D G AA+
Sbjct: 1764 SITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIG---DVCGPGWAAN 1820
Query: 478 SVQQRRQYRR-------QNQQSSSDSGSSSSSEDERP----KRSHVKNGEVG-------- 518
+ Y Q G +ED++P + N E+
Sbjct: 1821 ISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVT 1880
Query: 519 RRRRHSPSRSASPSPRKRQKETS-------PRGRRRRSPSPPPTRRRRSPSPAPPPRRRR 571
+ + + + +P+P T+ P ++P+ P + +P P P +
Sbjct: 1881 QPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 1940
Query: 572 TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPP 631
TPT P T + P +P+P P + +P T +P P P +P+ P
Sbjct: 1941 TPTTTPITTTTTVTP---TPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Query: 632 ---KRRVSHSPPPKQRSSPVTK--------RRSPSLSSKHRKGSSP-SRSTREARSPQPN 679
V+ +P P +P T +P+ + ++P + +T +P P
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052
Query: 680 KRHSPSPRPRAPQTSSSPPPVRRGASS------SPQRRQSPSPSTRPIRRVSRTPEPKKI 733
+P+ P T+ +P P G + + +P+P+ + + TP
Sbjct: 2053 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2112
Query: 734 KKAASPSPQSVRR-----VSSSRSVSGSPEPAAKKPPA------------PPSPVQSQSP 776
+P+P + ++++ +V+ +P P + P P+P +Q+P
Sbjct: 2113 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2172
Query: 777 STNWSPAVPVKKAKSPTPSPSP 798
+T P+ + TP+P+P
Sbjct: 2173 TT-----TPITTTTTVTPTPTP 2189
Score = 69.3 bits (168), Expect = 2e-11
Identities = 103/450 (22%), Positives = 140/450 (31%), Gaps = 80/450 (17%)
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
+K P P P TST+ + P P P + T P
Sbjct: 1393 DKCITTPSPPTTTPSPP---PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449
Query: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSP-RRRPSPRRRT----PPRRM 332
+ T + P T P P PSP PSP T PP
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPS----------PPTTTPSPPTTTPSPPTTTTTTPPPTTT 1499
Query: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
P PP P S+ +L +++ S + + + P PP T SPP T P++
Sbjct: 1500 PSPPTTTPITPPA-----STTTLPPTTTPSPPTTTTTTP--PPTTTPSPPTTTPITPPTS 1552
Query: 393 S---PPRRRHRPSPP----ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
+ PP PSPP TPPP T TP T S +++ T T
Sbjct: 1553 TTTLPPTT--TPSPPPTTTTTPPPTT----TPSPPTTTTPSPPTITTTTPPPTTTPSPPT 1606
Query: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
+P P P + + + +++
Sbjct: 1607 TTTTTPPPTTTPSPPTTT---------------------------PITPPTSTTTLPPTT 1639
Query: 506 RPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP----SPPPTRRRRSP 561
P SP + +PSP T P SP PPT +P
Sbjct: 1640 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTP 1699
Query: 562 SPAPPPRRR-RTPTPPPRRRTPSPPP-RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPP 619
SP P T T P TPSPPP +PSP +PSPP T PP
Sbjct: 1700 SPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT---------TPSPPTTTMTTLPPT 1750
Query: 620 PPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649
+ +P P + P ++P T
Sbjct: 1751 TTSSPLTTTPLPPSITPPTFSPFSTTTPTT 1780
Score = 68.2 bits (165), Expect = 3e-11
Identities = 95/573 (16%), Positives = 208/573 (36%), Gaps = 72/573 (12%)
Query: 274 TRPRSRSRSKSRSRTRSRSPSHTR-PRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM 332
T P + + + + T + +P+ T+ P + + + +P P+ + P+ T +
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1953
Query: 333 PPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSA 392
P P +++P ++ +++ + + + + + P + P T +P+
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2013
Query: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS 452
+P +P TP P +PT T + +P T T T +P+
Sbjct: 2014 TPITTTTTVTP--TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2071
Query: 453 PAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
P P + + + +++ + + + + + P + +
Sbjct: 2072 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2131
Query: 513 KNGEVGRRRRHSPSRSASPSPRKRQKETS------------PRGRRRRSPSPPPTRRRRS 560
+ + + +P+P Q T+ P ++P+ P +
Sbjct: 2132 TT---------TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2182
Query: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
+P P P +TPT P T + P +P+P P + +P T +P P
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVTP---TPTPTGTQTP-----TTTPITTTTTVTPTPT 2234
Query: 621 PKRRASPSPPP---KRRVSHSPPPKQRSSPVTK--------RRSPSLSSKHRKGSSP-SR 668
P +P+ P V+ +P P +P T +P+ + ++P +
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294
Query: 669 STREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS------SPQRRQSPSPSTRPIR 722
+T +P P +P+ P T+ +P P G + + +P+P+ +
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2354
Query: 723 RVSRTPEPKKIKKAASPSPQSVRR-----VSSSRSVSGSPEPAAKKPPA----------- 766
+ TP +P+P + ++++ +V+ +P P + P
Sbjct: 2355 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414
Query: 767 -PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
P+P +Q+P+T P+ + TP+P+P
Sbjct: 2415 PTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2442
Score = 63.2 bits (152), Expect = 1e-09
Identities = 132/709 (18%), Positives = 240/709 (33%), Gaps = 101/709 (14%)
Query: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKV 230
SP + +P P SP + +P T + P+ P T P P+
Sbjct: 1524 SPPTTTTTTPPPTTTPSP-----PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 231 KEPSVQEATSTSDILKVPKPEPIPEPKE-----------PSPEKNSK-KEKEKEKTRPRS 278
P+ + + P P P P PSP + T P +
Sbjct: 1579 SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1638
Query: 279 RSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR----RMPP 334
+ S + T + P+ T + S + P P PS T P M
Sbjct: 1639 TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTT 1698
Query: 335 PPRHRRSRSPVRRRRRSSASLSGSS-----SSSSSSRSRSPPKKP----PKRTSSPPRKT 385
P SP+ S++ + S ++ S + + SPP P T+S P T
Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTT 1758
Query: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV-SPG----------- 433
L PS +PP SP +T P T P + + + PG
Sbjct: 1759 TPLPPSITPPTF----SPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814
Query: 434 -----RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDK--GGKMAAADSVQQRRQYR 486
S + T + + V L ED+ GG + A + +
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQ 1874
Query: 487 RQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASP--SPRKRQKETSPRG 544
+ + +++++E+ P + +P+ + +P +P +P
Sbjct: 1875 CCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 1934
Query: 545 RRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604
+ +P T + + P P T TP TP +P+P +P +
Sbjct: 1935 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTP---TTTPITTTTTVTPTP---TPTGTQTP 1988
Query: 605 SPSPPPKRRTASPPPPPKRRASPSPPP---KRRVSHSPPPKQRSSPVTK--------RRS 653
+ +P T +P P P +P+ P V+ +P P +P T +
Sbjct: 1989 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2048
Query: 654 PSLSSKHRKGSSP-SRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS------ 706
P+ + ++P + +T +P P +P+ P T+ +P P G +
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2108
Query: 707 SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR-----VSSSRSVSGSPEPAA 761
+ +P+P+ + + TP +P+P + ++++ +V+ +P P
Sbjct: 2109 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2168
Query: 762 KKPPA------------PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
+ P P+P +Q+P+T P+ + TP+P+P
Sbjct: 2169 TQTPTTTPITTTTTVTPTPTPTGTQTPTT-----TPITTTTTVTPTPTP 2212
Score = 62.4 bits (150), Expect = 2e-09
Identities = 79/444 (17%), Positives = 165/444 (37%), Gaps = 79/444 (17%)
Query: 390 PSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449
P+ P+PP T P T + TP + T + +P T+ VT +
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQ 1940
Query: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509
+P+ P ++ + G + + +++ + + + + + P
Sbjct: 1941 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITT----------TTTVTPTPTPTGTQTPTT 1990
Query: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569
+ + + + + +P+P +P G + +P+ P + +P P P
Sbjct: 1991 TPI-----------TTTTTVTPTP-------TPTGTQ--TPTTTPITTTTTVTPTPTPTG 2030
Query: 570 RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP 629
+TPT P T + P +P+P P + +P T +P P P +P+
Sbjct: 2031 TQTPTTTPITTTTTVTP---TPTPTGTQTP-----TTTPITTTTTVTPTPTPTGTQTPTT 2082
Query: 630 PP---KRRVSHSPPPKQRSSPVTK--------RRSPSLSSKHRKGSSP-SRSTREARSPQ 677
P V+ +P P +P T +P+ + ++P + +T +P
Sbjct: 2083 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2142
Query: 678 PNKRHSPSPRPRAPQTSSSPPPVRRGASS------SPQRRQSPSPSTRPIRRVSRTPEPK 731
P +P+ P T+ +P P G + + +P+P+ + + TP
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Query: 732 KIKKAASPSPQSVRR-----VSSSRSVSGSPEPAAKKPPA------------PPSPVQSQ 774
+P+P + ++++ +V+ +P P + P P+P +Q
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2262
Query: 775 SPSTNWSPAVPVKKAKSPTPSPSP 798
+P+T P+ + TP+P+P
Sbjct: 2263 TPTT-----TPITTTTTVTPTPTP 2281
Score = 52.0 bits (123), Expect = 2e-06
Identities = 70/300 (23%), Positives = 97/300 (32%), Gaps = 28/300 (9%)
Query: 171 SPRRRKSRSPSPRRRSSP--VRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228
SP + +P P SP + P T + P+ P TP P S
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRT 288
P+ + T+ P P P P +P T P + + S + T
Sbjct: 1515 TTLPPTTTPSPPTTTTT-TPPPTTTPSPPTTTPIT----PPTSTTTLPPTTTPSPPPTTT 1569
Query: 289 RSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRT----PPRRMPPPPRHRRSRSP 344
+ P+ T + S P P PSP T PP P PP P
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629
Query: 345 VRRRRRSSASL-SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHRP 401
+ S +++++ + P P T SPP T P + P P
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 402 SPP----ATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
SPP TP P T S +P + T S + SP T T SP+ P P
Sbjct: 1690 SPPTTTMTTPSPTTTPS-SPITTTTTPSSTTTPSPPPT---------TMTTPSPTTTPSP 1739
Score = 32.3 bits (72), Expect = 2.0
Identities = 18/43 (41%), Positives = 22/43 (51%), Gaps = 2/43 (4%)
Query: 560 SPSPAPPPRRRRTPTPPPRRRTPS-PPPRRRSPSPRRYSPPIQ 601
+PSP P P + TPTP TPS P P + P + PP Q
Sbjct: 4379 TPSPTPTP-SKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420
Score = 30.4 bits (67), Expect = 7.8
Identities = 15/40 (37%), Positives = 20/40 (50%), Gaps = 3/40 (7%)
Query: 549 SPSPPPTRRRRSPSPAPPPRRRRTPTP---PPRRRTPSPP 585
+PSP PT + +P+P+ P PTP PP PP
Sbjct: 4379 TPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPP 4418
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 109 bits (272), Expect = 1e-23
Identities = 113/459 (24%), Positives = 162/459 (35%), Gaps = 77/459 (16%)
Query: 349 RRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP 408
+ S SL + + + + P+ PP SPP K P PP+ ++P P PP
Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPP----SPPGK-----PQGPPPQGGNQPQGPPPPP 75
Query: 409 PKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEED 468
K + P PQ N K + PG+ G + G + R SP KP +
Sbjct: 76 GKPQ-GPPPQGGN---KPQGPPPPGKPQGPPPQ--GDKSRSPRSPPGKP------QGPPP 123
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+GG + Q + G + + P + + SRS
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----------QGDNKSRS 172
Query: 529 ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRR 588
+ P K Q G + + P PPP + P PP + PPP + PPP+
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGK----PQGPPPQGGNKPQGPPPPGKPQGPPPQG 228
Query: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648
+ S SPP + P P + PPPPP + P P + PPP + P
Sbjct: 229 DNKSQSARSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 287
Query: 649 TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSP 708
+ S S SS+ G + PQ P P P PQ PPP
Sbjct: 288 PQGGSKSRSSRSPPGKPQGPPPQGGNQPQ-----GPPPPPGKPQ---GPPP------QGG 333
Query: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK----P 764
+ Q P P +P P PQ + S+RS G P+ ++ P
Sbjct: 334 NKPQGPPPPGKP----------------QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNP 377
Query: 765 PAPP-----SPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
PP +P Q Q+P P P + + PS P
Sbjct: 378 QGPPPPAGGNPQQPQAPPAG-QPQGPPRPPQGGRPSRPP 415
Score = 95.9 bits (237), Expect = 2e-19
Identities = 91/361 (25%), Positives = 134/361 (37%), Gaps = 52/361 (14%)
Query: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551
SS+ + + S++E P S + G + PSP + + P+G +
Sbjct: 14 SSAQNLNEDVSQEESP--SLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71
Query: 552 PPPTRRRRSPSPA--------PPPRRRRTPTPP-PRRRTPSPPP-RRRSPSPRRYSPPIQ 601
PPP + + P P PPP + + P P + R+P PP + + P P+ + P
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQP-- 129
Query: 602 RRYSPSPPPKRRTASPP--------PPPKRRASPSPPP---KRRVSHSPPPKQRSSPV-- 648
P PPP + PP PPP + PP K R S SPP K + P
Sbjct: 130 --QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 649 -TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR-PRAPQTSSSPPPVRRG--- 703
+ + P +G P + P P K P P+ Q++ SPP +G
Sbjct: 188 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPP 247
Query: 704 -ASSSPQRRQSP--SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPA 760
+ PQ P P P + ++ P K P PQ + SSRS G P+
Sbjct: 248 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Query: 761 AKK-------PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKK 813
+ PP PP Q P P P P P P+ +GG K +
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP--------PPPGKPQGPPPQGGSKSRSA 359
Query: 814 K 814
+
Sbjct: 360 R 360
Score = 95.9 bits (237), Expect = 2e-19
Identities = 99/426 (23%), Positives = 153/426 (35%), Gaps = 46/426 (10%)
Query: 209 SPSPAPEKKEKTPE-LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK 267
+P AP + P+ P P K + P Q P P +P+ P P+ +K
Sbjct: 35 NPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQG-----PPPPPGKPQGPPPQGGNKP 89
Query: 268 EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRT 327
+ +P+ +SR+ RSP + ++ P P + P P+
Sbjct: 90 QGPPPPGKPQGPPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148
Query: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR 387
P+ PPP + + + RSS S G P PP PP K
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP-----PPGK--- 200
Query: 388 LSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK 447
P PP+ ++P P PPP P PQ N+++ +R PG+ G + G +
Sbjct: 201 --PQGPPPQGGNKPQGP--PPPGKPQGPPPQGDNKSQSARSP--PGKPQGPPPQG-GNQP 253
Query: 448 RESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP 507
+ P P KP+ + +G + Q GS S S P
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPG------------KPQGPPPQGGSKSRSSRSPP 301
Query: 508 KRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPP 567
+ + G + + P P Q P+G PPP + + P P
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-------PPPPGKPQGPPPQGGS 354
Query: 568 RRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR-YSPSPPPKRRTASPPPPPKRRAS 626
+ R +PP + P PP++ +P+ PP P PP + PP PP+
Sbjct: 355 KSRSARSPPGK---PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQ-GGR 410
Query: 627 PSPPPK 632
PS PP+
Sbjct: 411 PSRPPQ 416
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 107 bits (268), Expect = 4e-23
Identities = 152/653 (23%), Positives = 228/653 (34%), Gaps = 108/653 (16%)
Query: 196 SHSRSPRHRTKSR-----------SPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDI 244
SH P+ TK+R P+PA K + TP+L P+ + P + T
Sbjct: 772 SHFTPPQTPTKTRPGSPQALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRG 831
Query: 245 LKVPKPEPI--------PEPKEPS-----PEKNSKKEKEKEKTRPRSRSRSKSRSRTRSR 291
P+P+ P P P P E + E RP+ R+ S +R
Sbjct: 832 FAYVLPQPVEGEVGPAAPGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDS 891
Query: 292 SPSH-------------TRPRRRHRSRSRSYSPRRRPSPRRRPS----PRRRTPPRRMPP 334
P T RR RS S + R S PR++ PP PP
Sbjct: 892 EPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPP---PP 948
Query: 335 PPRHRRSRSP--------------------VRRRRRSSASLSGSSSSSSSSRSRSPPKKP 374
PP+ S VR + R ++ L+GS + S+ +S
Sbjct: 949 PPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAML 1008
Query: 375 PKRTSSPPRKTRRLSPSASPPRRRHRPSPP--ATPPPKTRHSPTPQQSNRTRKSRVSVSP 432
+ + R P P R P P AT +H R ++S
Sbjct: 1009 ELSSIGGGGRAARRPPEGHPTPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSG 1068
Query: 433 GRTSGKVTKHKGTEKRESPSP-------APKPRKVELSESEEDKGGKMAA--ADSVQQRR 483
T T +G + P P +PR E+ + G +A A + +RR
Sbjct: 1069 PVTGLLATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVE-GPPLAKVEASATLKRR 1127
Query: 484 QYRRQNQQSS-------SDSGSSSSSEDER-------PKRSHVKNGEVGRRRRHSPSRSA 529
+QNQQ + SD+ ER P S NG RRR + ++
Sbjct: 1128 IRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAG 1187
Query: 530 SPS--PRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPR 587
P P E P P PPP R P+ P + P P+ + P
Sbjct: 1188 PPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTS 1247
Query: 588 RRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP 647
++ P P SP ++R + PP + PPPPP +P P + V+ P SP
Sbjct: 1248 KKVPLPGPGSPEVKRAHGTPPPV---SPKPPPPP-----TAPKPVKAVAGLPSGSAGPSP 1299
Query: 648 V-TKRRSPSLSSKHRKGSSPSRSTREARSPQPN--KRHSPSPRPR----APQTSSSPPPV 700
+ R P + G+ PS A+ P P H P+ PR A +++PP
Sbjct: 1300 APSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359
Query: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSV 753
GAS RQ ++ + + E +KI++ + P+ S+ S+
Sbjct: 1360 PEGASPGDSARQKLEETSACLAAALQAVE-EKIRQEDAQGPRDSAAEKSTGSI 1411
Score = 99.0 bits (245), Expect = 2e-20
Identities = 151/668 (22%), Positives = 229/668 (34%), Gaps = 110/668 (16%)
Query: 250 PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSY 309
P P P+E P ++ K + R T +P T + R S
Sbjct: 733 PAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALG 792
Query: 310 SP--------RRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
P + +P+P+ P R PR +P P HR + + + +
Sbjct: 793 GPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAAPGPA 852
Query: 362 SSSSRSRSPPK-KPPKRTSSPPRKTRRL------SPSASPPRRRHRPSPPATPPPKTRHS 414
+ P PP+ + P R +R + S S P R P A P ++
Sbjct: 853 PPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGP----YA 908
Query: 415 PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474
++ R+ R + + +++ P P P R S +
Sbjct: 909 TVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSALASANLADEPVP 968
Query: 475 AADS----VQQRRQYRRQNQQSSS-DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS--- 526
A+ + R Q RR + + S D+GS+ S + G GR R P
Sbjct: 969 DAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEGHP 1028
Query: 527 --RSASPSPR---------KRQKETSPRGR---RRRSPSPPPT----RRRRSPSPAPPP- 567
R ASP P K ++ P G RRR+ S P T RR P + P
Sbjct: 1029 TPRPASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPVTGLLATARRGPGESADPG 1088
Query: 568 ---------RRRRTPT--------PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPP 610
+R R P+ PP + S +RR + + ++ + S
Sbjct: 1089 PFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTV 1148
Query: 611 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
KRR P +R A P PPP V H+ R P +++ P + P +
Sbjct: 1149 KRR----PKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTD 1204
Query: 671 REARSPQP---NKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP--SPSTRPIRRVS 725
P P + P+ P +P+ + P + S +P ++ P P + ++R
Sbjct: 1205 LAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAH 1264
Query: 726 RTPEPKKIKKAASPS-PQSVRRVSSSRSVSGSPEPA---AKKPPAPPSPVQSQSPSTNWS 781
TP P K P+ P+ V+ V+ S S P PA A++PPA + PS S
Sbjct: 1265 GTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGAS 1324
Query: 782 PAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAA 841
PA P PSP P H K +A AAAA
Sbjct: 1325 PAKP--------PSPGAPA--------------------------LHVPAKPPRAAAAAA 1350
Query: 842 AAAVTPAA 849
AAA P A
Sbjct: 1351 AAAAAPPA 1358
Score = 67.8 bits (164), Expect = 4e-11
Identities = 105/424 (24%), Positives = 151/424 (35%), Gaps = 51/424 (12%)
Query: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSP---TPQQSNRTRKSRVSVSPGRTSGKVTKH 442
RR +P + P PP P P SP T Q S + + + +++ G T
Sbjct: 619 RRKAPQSLEVMAIESPPPPE-PTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTT-- 675
Query: 443 KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSS 502
EK S P P PR +S GG+ S Q+ SS S S
Sbjct: 676 ---EKPSSHLP-PTPRATTRQDSS--LGGRARHMSSSQELLGDGPPGP-SSPMSRSQEYL 728
Query: 503 EDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRR---- 558
DE P R HS R++ P + ++ P G +P PT+ R
Sbjct: 729 LDEGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSP 788
Query: 559 ---RSPSPAPPPRRRRTPTP---PPRRRTPSPPPRRRSPSPRRYS----PPIQRRYSPS- 607
P P + PTP PP R SP +SP+ R ++ P++ P+
Sbjct: 789 QALGGPHGPAPATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLPQPVEGEVGPAA 848
Query: 608 ---PPPKRRTASPP--PPPKRRASPSPPPKRRVSHSPPPKQRSSP------VTKRRSPSL 656
PP TA P PP+ A P P KR S + S P V P
Sbjct: 849 PGPAPPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYA 908
Query: 657 SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS--SSPQRRQSP 714
+ + R G S S N+ S + RPR + PPP +R +S +S P
Sbjct: 909 TVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPR--KKGPPPPPPKRSSSALASANLADEP 966
Query: 715 SPSTRP------IRRVSRTPE--PKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766
P P +R R + ++ S +S+ + S+ G A + P
Sbjct: 967 VPDAEPEDGLLGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGGGGRAARRPPEG 1026
Query: 767 PPSP 770
P+P
Sbjct: 1027 HPTP 1030
Score = 31.6 bits (70), Expect = 3.5
Identities = 44/170 (25%), Positives = 61/170 (35%), Gaps = 42/170 (24%)
Query: 668 RSTREARSPQPNKRHSPSPRPRAPQTSS-----SPPPVRRGASSSPQRRQSPSPSTRPIR 722
R E + + K R +APQ+ SPPP +P QSP +T
Sbjct: 600 RKLAELQKAEYAKYEGGPLRRKAPQSLEVMAIESPPP----PEPTPADCQSPKMTTFQDS 655
Query: 723 RVSRT------------PEPKKIKKAASPSPQSVRRVSSS-----RSVSGSPEPAAKKPP 765
+S P +K P+P++ R SS R +S S E PP
Sbjct: 656 ELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQDSSLGGRARHMSSSQELLGDGPP 715
Query: 766 APPSPV---------QSQSPSTNWSPAVP------VKKAKSPTPSPSPPR 800
P SP+ + +P T A P +K+A P P P PR
Sbjct: 716 GPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKRASVP-PVPGKPR 764
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 107 bits (268), Expect = 4e-23
Identities = 169/648 (26%), Positives = 244/648 (37%), Gaps = 110/648 (16%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS 187
++ +K +Q E+EK S + + +D+ S R E + + ++S S RSS
Sbjct: 120 RDLLKAKQTEKEK--SQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSS 177
Query: 188 PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKV 247
+ +E+ R R + K RS S +K +TP+ + K S SD K
Sbjct: 178 KLHKEKTRKE-RELKSGHKDRSKS---HRKRETPKSYKTVDSPKRRSRSPHRKWSDSSK- 232
Query: 248 PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR 307
++ SP S + + SRS + S + +SP T SR +
Sbjct: 233 ---------QDDSPSGASYGQ---DYDLSPSRSHTSSNYDSYKKSPGST-------SRRQ 273
Query: 308 SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS 367
S SP P + PS + + R P R +RS SP RRR SS SGS S
Sbjct: 274 SVSP-----PYKEPSAYQSST-RSPSPYSRRQRSVSPYSRRRSSSYERSGSYS------G 321
Query: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHRPSPPATPPPKTRHSPTPQQSNRTRK 425
RSP +R+SSP R LS S P R+ + R PA + HS + S+R+R
Sbjct: 322 RSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRH 381
Query: 426 SRVSVSPGR-----TSGKVTKHKGTE------------KRESPSPAPKPRKVELSESEED 468
S S+SP R + G K E K SP PRK S +D
Sbjct: 382 S--SISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 469 KG-----------GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517
G + +A D+ + ++SSD+G DE ++ VK+
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKL--DENSEKHLVKD--- 494
Query: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPP 577
+ +R + P K + T +PPP P+ A PP T TPPP
Sbjct: 495 ---LKAQGTRDSKPIALKEEIVTPKETETSEKETPPPL-----PTIASPPPPLPTTTPPP 546
Query: 578 RRRTPSPPPRRRSPSPRRYS--PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRV 635
+TP PP P+ + PP Q +S P T P K A S
Sbjct: 547 --QTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQ------ 598
Query: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRK--------------GSSPSRSTREARSPQPNKR 681
++S PP Q S V + S + + H K G S +E +P K+
Sbjct: 599 ANSQPPVQVS--VKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKK 656
Query: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729
R R T PP G SP P T P + + P+
Sbjct: 657 EK-EQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPK 703
Score = 78.6 bits (192), Expect = 2e-14
Identities = 143/604 (23%), Positives = 219/604 (36%), Gaps = 91/604 (15%)
Query: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
SS S + S K +R + R + R +HR S +T + +
Sbjct: 77 SSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEV 136
Query: 420 SNRT--RKSRVSVSPGRTS--------GKVTKHKGTEKRESPSPAPKPRKV-ELSESEED 468
S+++ K R+S S R++ +V K E R S K RK EL +D
Sbjct: 137 SSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKD 196
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSD--SGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
+ ++ + + ++S S S SS +D+ P G+ SPS
Sbjct: 197 RSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS-----GASYGQDYDLSPS 251
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPP---PTRRRRSP-SPAPPPRRRRTPTPPPRRRTP 582
RS + S K++ RR+S SPP P+ + S SP+P RR+R+ +P RRR+
Sbjct: 252 RSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSS 311
Query: 583 SPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPPPPPKRRASPS---PPPKRRVSHS 638
S RS S SP P RR S SP +R+ S P P R++ S P R S S
Sbjct: 312 S---YERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSS 368
Query: 639 PPPKQRSSPVTKRRSPS---LSSKHRKGSSPSRSTRE-------ARSPQPNKRHSPSPRP 688
K+RSS ++ S S L G+ SR +E A+ + SP P
Sbjct: 369 HSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLP 428
Query: 689 RAPQTSSSPPPVRRGASSSPQ--RRQSPSPSTRPIR------RVSRTPEPKKIK------ 734
R +S + P+ + + +P T + V + + K+K
Sbjct: 429 RKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSE 488
Query: 735 ---------------KAASPSPQSVRRVSSSRSVSGSPEP----AAKKPPAPPSPVQSQS 775
K + + V + S +P P A+ PP P + Q+
Sbjct: 489 KHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQT 548
Query: 776 PSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835
P P +P + P P PS P S + H K +
Sbjct: 549 PPLPPLPPIPALPQQPPLP-PSQPAFS--QVPASSTSTLPPSTHSKTSAVSSQANSQPPV 605
Query: 836 AVAAAAAAAVTPAAIAAATTTL----------------AQEEPVAAPEPKKETESEAEDN 879
V+ +VT A T+TL + +E + + KKE E
Sbjct: 606 QVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHL 665
Query: 880 LDDL 883
L DL
Sbjct: 666 LTDL 669
Score = 48.5 bits (114), Expect = 3e-05
Identities = 71/328 (21%), Positives = 113/328 (34%), Gaps = 18/328 (5%)
Query: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVS---PGRTSGKVTKHKGTEKRESPSPAPKPR 458
+PP P + H ++ R R+S V V P +TS K T GT + +P P
Sbjct: 1029 APPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETT-SGTSTEPVKNSSPAPP 1087
Query: 459 KVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG 518
+ + E G + AD QQ Q + S + S + N E+
Sbjct: 1088 QPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQ 1147
Query: 519 RRRR---HSPSRSASPSPRKRQKET-SPRGRRRRSPSPP-------PTRRRRSPSPAPPP 567
++ S S + +++ ET +P + +PS P T S +PA
Sbjct: 1148 QQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQ 1207
Query: 568 RRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP 627
+ + S + P RR P + PP PP P
Sbjct: 1208 NILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPPEPPGPPPPP 1267
Query: 628 SPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR 687
PPP S P++ + VT LS + P E ++ +P +S PR
Sbjct: 1268 PPPPLVEGDLSSAPQELNPAVTAALLQLLSQP--EAEPPGHLPHEHQALRP-MEYSTRPR 1324
Query: 688 PRAPQTSSSPPPVRRGASSSPQRRQSPS 715
P ++ P A + +R P+
Sbjct: 1325 PNRTYGNTDGPETGFSAIDTDERNSGPA 1352
Score = 36.6 bits (83), Expect = 0.11
Identities = 62/285 (21%), Positives = 100/285 (35%), Gaps = 37/285 (12%)
Query: 151 KDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS--------RSPR 202
K+ E K+S E ++ RS + KS + + + E K S S +
Sbjct: 430 KENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEK 489
Query: 203 HRTK------SRSPSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255
H K +R P K+E TP+ E S K P + S L P P
Sbjct: 490 HLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTP 549
Query: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP 315
P P P + ++ P + S+ + + S P T + S + P +
Sbjct: 550 PLPPLPPIPALPQQPP--LPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQV 607
Query: 316 SPRRRPS-----PRRRT---PPRRMPP---------PPRHRRSRSPVRRRR--RSSASLS 356
S + + S P +T PP +PP P+ PV++ + R+ L+
Sbjct: 608 SVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLT 667
Query: 357 GSSSSSS-SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR 400
SPP P + +PP++ + P PR R
Sbjct: 668 DLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGER 712
Score = 32.0 bits (71), Expect = 2.7
Identities = 21/84 (25%), Positives = 34/84 (40%), Gaps = 3/84 (3%)
Query: 646 SPVTKRRSPSLSSKHR---KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR 702
S + K + P+ S + K S P R PQ P P P PPP+
Sbjct: 1215 SQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAEKRPPEPPGPPPPPPPPPLVE 1274
Query: 703 GASSSPQRRQSPSPSTRPIRRVSR 726
G SS + +P+ + ++ +S+
Sbjct: 1275 GDLSSAPQELNPAVTAALLQLLSQ 1298
Score = 31.6 bits (70), Expect = 3.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 806 GGGKKKKKKKDKKHKKDKKHKKHK-KHKKEKAV----AAAAAAAVTPAA----IAAATTT 856
GGG + ++H+ KHK+HK KH K+ + AA+ + P I++ + T
Sbjct: 26 GGGSSNSR---ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDT 82
Query: 857 LAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRS 894
+ ++ + ++ E D D L KH + RS
Sbjct: 83 FS-DDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS 119
Score = 30.8 bits (68), Expect = 5.9
Identities = 32/143 (22%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 637 HSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSS 696
HS P Q+ + +L+ ++ + E +P+ + + +PS AP S
Sbjct: 1141 HSNPEMQQQLEALNQSISALTE-----ATSQQQDSETMAPEESLKEAPS----APVILPS 1191
Query: 697 PPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP----KKIKKAASPSPQSVRRVSSSRS 752
ASS+P Q+ + ++ +T EP ++ + PQ RR +
Sbjct: 1192 AEQTTLEASSTPADMQNILAVL--LSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQ 1249
Query: 753 VSGS----PEPAAKKPPAPPSPV 771
+ PEP PP PP P+
Sbjct: 1250 EEAAEKRPPEPPGPPPPPPPPPL 1272
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 107 bits (268), Expect = 4e-23
Identities = 169/648 (26%), Positives = 244/648 (37%), Gaps = 110/648 (16%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS 187
++ +K +Q E+EK S + + +D+ S R E + + ++S S RSS
Sbjct: 120 RDLLKAKQTEKEK--SQEVSSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSS 177
Query: 188 PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKV 247
+ +E+ R R + K RS S +K +TP+ + K S SD K
Sbjct: 178 KLHKEKTRKE-RELKSGHKDRSKS---HRKRETPKSYKTVDSPKRRSRSPHRKWSDSSK- 232
Query: 248 PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSR 307
++ SP S + + SRS + S + +SP T SR +
Sbjct: 233 ---------QDDSPSGASYGQ---DYDLSPSRSHTSSNYDSYKKSPGST-------SRRQ 273
Query: 308 SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRS 367
S SP P + PS + + R P R +RS SP RRR SS SGS S
Sbjct: 274 SVSP-----PYKEPSAYQSST-RSPSPYSRRQRSVSPYSRRRSSSYERSGSYS------G 321
Query: 368 RSPPKKPPKRTSSPPRKTRRLSPSASPPRR--RHRPSPPATPPPKTRHSPTPQQSNRTRK 425
RSP +R+SSP R LS S P R+ + R PA + HS + S+R+R
Sbjct: 322 RSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRH 381
Query: 426 SRVSVSPGR-----TSGKVTKHKGTE------------KRESPSPAPKPRKVELSESEED 468
S S+SP R + G K E K SP PRK S +D
Sbjct: 382 S--SISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLPRKENSSVEAKD 439
Query: 469 KG-----------GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517
G + +A D+ + ++SSD+G DE ++ VK+
Sbjct: 440 SGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKL--DENSEKHLVKD--- 494
Query: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPP 577
+ +R + P K + T +PPP P+ A PP T TPPP
Sbjct: 495 ---LKAQGTRDSKPIALKEEIVTPKETETSEKETPPPL-----PTIASPPPPLPTTTPPP 546
Query: 578 RRRTPSPPPRRRSPSPRRYS--PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRV 635
+TP PP P+ + PP Q +S P T P K A S
Sbjct: 547 --QTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQ------ 598
Query: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRK--------------GSSPSRSTREARSPQPNKR 681
++S PP Q S V + S + + H K G S +E +P K+
Sbjct: 599 ANSQPPVQVS--VKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKK 656
Query: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPE 729
R R T PP G SP P T P + + P+
Sbjct: 657 EK-EQRTRHLLTDLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPK 703
Score = 78.6 bits (192), Expect = 2e-14
Identities = 143/604 (23%), Positives = 219/604 (36%), Gaps = 91/604 (15%)
Query: 360 SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQ 419
SS S + S K +R + R + R +HR S +T + +
Sbjct: 77 SSDSDTFSDDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRSRDLLKAKQTEKEKSQEV 136
Query: 420 SNRT--RKSRVSVSPGRTS--------GKVTKHKGTEKRESPSPAPKPRKV-ELSESEED 468
S+++ K R+S S R++ +V K E R S K RK EL +D
Sbjct: 137 SSKSGSMKDRISGSSKRSNEETDDYGKAQVAKSSSKESRSSKLHKEKTRKERELKSGHKD 196
Query: 469 KGGKMAAADSVQQRRQYRRQNQQSSSD--SGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
+ ++ + + ++S S S SS +D+ P G+ SPS
Sbjct: 197 RSKSHRKRETPKSYKTVDSPKRRSRSPHRKWSDSSKQDDSPS-----GASYGQDYDLSPS 251
Query: 527 RSASPSPRKRQKETSPRGRRRRSPSPP---PTRRRRSP-SPAPPPRRRRTPTPPPRRRTP 582
RS + S K++ RR+S SPP P+ + S SP+P RR+R+ +P RRR+
Sbjct: 252 RSHTSSNYDSYKKSPGSTSRRQSVSPPYKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSS 311
Query: 583 SPPPRRRSPSPRRYSP-PIQRRYSPSPPPKRRTASPPPPPKRRASPS---PPPKRRVSHS 638
S RS S SP P RR S SP +R+ S P P R++ S P R S S
Sbjct: 312 S---YERSGSYSGRSPSPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSS 368
Query: 639 PPPKQRSSPVTKRRSPS---LSSKHRKGSSPSRSTRE-------ARSPQPNKRHSPSPRP 688
K+RSS ++ S S L G+ SR +E A+ + SP P
Sbjct: 369 HSKKKRSSSRSRHSSISPVRLPLNSSLGAELSRKKKERAAAAAAAKMDGKESKGSPVFLP 428
Query: 689 RAPQTSSSPPPVRRGASSSPQ--RRQSPSPSTRPIR------RVSRTPEPKKIK------ 734
R +S + P+ + + +P T + V + + K+K
Sbjct: 429 RKENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSE 488
Query: 735 ---------------KAASPSPQSVRRVSSSRSVSGSPEP----AAKKPPAPPSPVQSQS 775
K + + V + S +P P A+ PP P + Q+
Sbjct: 489 KHLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQT 548
Query: 776 PSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEK 835
P P +P + P P PS P S + H K +
Sbjct: 549 PPLPPLPPIPALPQQPPLP-PSQPAFS--QVPASSTSTLPPSTHSKTSAVSSQANSQPPV 605
Query: 836 AVAAAAAAAVTPAAIAAATTTL----------------AQEEPVAAPEPKKETESEAEDN 879
V+ +VT A T+TL + +E + + KKE E
Sbjct: 606 QVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHL 665
Query: 880 LDDL 883
L DL
Sbjct: 666 LTDL 669
Score = 47.8 bits (112), Expect = 5e-05
Identities = 74/337 (21%), Positives = 122/337 (36%), Gaps = 27/337 (8%)
Query: 402 SPPATPPPKTRHSPTPQQSNRTRKSRVSVS---PGRTSGKVTKHKGTEKRESPSPAPKPR 458
+PP P + H ++ R R+S V V P +TS K T GT + +P P
Sbjct: 1029 APPDLPHWQDCHELWSKKRRRQRQSGVVVEEPPPSKTSRKETT-SGTSTEPVKNSSPAPP 1087
Query: 459 KVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVG 518
+ + E G + AD QQ Q + S + S + N E+
Sbjct: 1088 QPAPGKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQ 1147
Query: 519 RRRR---HSPSRSASPSPRKRQKET-SPRGRRRRSPSPP---PTRRRRSPSPAPPPRRRR 571
++ S S + +++ ET +P + +PS P P+ + + + P +
Sbjct: 1148 QQLEALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQ 1207
Query: 572 TPTP---PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPP---PPPKRRA 625
+T P + + S P R +P+ P + A PP PP KR
Sbjct: 1208 NILAVLLSQLMKTQEPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPP 1267
Query: 626 S-------PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQP 678
P PPP S P++ + VT LS + P E ++ +P
Sbjct: 1268 EPPGPPPPPPPPPLVEGDLSSAPQELNPAVTAALLQLLSQP--EAEPPGHLPHEHQALRP 1325
Query: 679 NKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS 715
+S PRP ++ P A + +R P+
Sbjct: 1326 -MEYSTRPRPNRTYGNTDGPETGFSAIDTDERNSGPA 1361
Score = 40.8 bits (94), Expect = 0.006
Identities = 58/307 (18%), Positives = 116/307 (37%), Gaps = 24/307 (7%)
Query: 113 QENIAGIPSAFLELKKEEI----KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER 168
+E + IPSA L+L + +R ++ L S +D + K + ++ E
Sbjct: 983 REEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDFLKDVELSKMAPPDLPHWQDCHEL 1042
Query: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228
RRR+ +S P + RK + S + K+ SP+P P+P+
Sbjct: 1043 WSKKRRRQRQSGVVVEEPPPSKTSRKETTSGTSTEPVKNSSPAP-----------PQPAP 1091
Query: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK-----TRPRSRSRSK 283
E +A +DI + + + + + + P + + +
Sbjct: 1092 GKVESGAGDAIGLADITQQLNQSELAVLLNLLQSQTDLSIPQMAQLLNIHSNPEMQQQLE 1151
Query: 284 SRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS-PRRRPSPRRRTPPRRMPPPPRHRRSR 342
+ +++ S T ++ + + S + PS P PS + T P +
Sbjct: 1152 ALNQSISALTEATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADM-QNIL 1210
Query: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPS 402
+ + + + +GS ++S ++ P + P+RT + P++ P P + P
Sbjct: 1211 AVLLSQLMKTQEPAGSLEENNSDKNSGP--QGPRRTPTMPQEEAAACPPHILPPEKRPPE 1268
Query: 403 PPATPPP 409
PP PPP
Sbjct: 1269 PPGPPPP 1275
Score = 36.6 bits (83), Expect = 0.11
Identities = 62/285 (21%), Positives = 100/285 (35%), Gaps = 37/285 (12%)
Query: 151 KDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHS--------RSPR 202
K+ E K+S E ++ RS + KS + + + E K S S +
Sbjct: 430 KENSSVEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVKLDENSEK 489
Query: 203 HRTK------SRSPSPAPEKKE-KTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE 255
H K +R P K+E TP+ E S K P + S L P P
Sbjct: 490 HLVKDLKAQGTRDSKPIALKEEIVTPKETETSEKETPPPLPTIASPPPPLPTTTPPPQTP 549
Query: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP 315
P P P + ++ P + S+ + + S P T + S + P +
Sbjct: 550 PLPPLPPIPALPQQPP--LPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQANSQPPVQV 607
Query: 316 SPRRRPS-----PRRRT---PPRRMPP---------PPRHRRSRSPVRRRR--RSSASLS 356
S + + S P +T PP +PP P+ PV++ + R+ L+
Sbjct: 608 SVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETLPSKPVKKEKEQRTRHLLT 667
Query: 357 GSSSSSS-SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR 400
SPP P + +PP++ + P PR R
Sbjct: 668 DLPLPPELPGGDLSPPDSPEPKAITPPQQPYKKRPKICCPRYGER 712
Score = 33.1 bits (74), Expect = 1.2
Identities = 22/84 (26%), Positives = 37/84 (44%), Gaps = 10/84 (11%)
Query: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR 702
+ S P RR+P++ + P E R P+P P P P P PPP+
Sbjct: 1234 KNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEP-----PGPPPPPP-----PPPLVE 1283
Query: 703 GASSSPQRRQSPSPSTRPIRRVSR 726
G SS + +P+ + ++ +S+
Sbjct: 1284 GDLSSAPQELNPAVTAALLQLLSQ 1307
Score = 32.0 bits (71), Expect = 2.7
Identities = 45/201 (22%), Positives = 74/201 (36%), Gaps = 17/201 (8%)
Query: 218 EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN--SKKEKEKEKTR 275
E T + + E S++EA S IL + + P+ +N + + KT+
Sbjct: 1162 EATSQQQDSETMAPEESLKEAPSAPVILPSAEQTTLEASSTPADMQNILAVLLSQLMKTQ 1221
Query: 276 PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335
+ S ++ S S R + + + P P +R P P PP PPP
Sbjct: 1222 EPAGSLEENNSDKNSGPQGPRRTPTMPQEEAAACPPHILPPEKRPPEPPGPPPP---PPP 1278
Query: 336 PRHRRSRSPVRRRRRSSA--SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393
P P+ SSA L+ + +++ P +PP P + + L P
Sbjct: 1279 P-------PLVEGDLSSAPQELNPAVTAALLQLLSQPEAEPPGHL---PHEHQALRPMEY 1328
Query: 394 PPRRRHRPSPPATPPPKTRHS 414
R R + T P+T S
Sbjct: 1329 STRPRPNRTYGNTDGPETGFS 1349
Score = 31.6 bits (70), Expect = 3.5
Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 13/98 (13%)
Query: 806 GGGKKKKKKKDKKHKKDKKHKKHK-KHKKEKAV----AAAAAAAVTPAA----IAAATTT 856
GGG + ++H+ KHK+HK KH K+ + AA+ + P I++ + T
Sbjct: 26 GGGSSNSR---ERHRLVSKHKRHKSKHSKDMGLVTPEAASLGTVIKPLVEYDDISSDSDT 82
Query: 857 LAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRS 894
+ ++ + ++ E D D L KH + RS
Sbjct: 83 FS-DDMAFKLDRRENDERRGSDRSDRLHKHRHHQHRRS 119
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 106 bits (265), Expect = 9e-23
Identities = 131/529 (24%), Positives = 199/529 (37%), Gaps = 61/529 (11%)
Query: 303 RSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRS-----------RSPVRRRRRS 351
R ++++ + R P+ R R P PPPP + R P+ R
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 352 --------SASLSGSSSSSSSSRSRSPPKKPP---KRTSSPPRKTRRLSPSASPPRRRHR 400
SA +G + S+ +S SR+P +PP + +PP K P +SP R
Sbjct: 65 IGGATIPESAPRAGPTRSAGTS-SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA--- 120
Query: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPA-PKPRK 459
S P P + + + + +P R++ + T P+P P P
Sbjct: 121 -SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS---GPTPGTPSPAM 176
Query: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519
S + + G A S + R + SS S S++ +R G + R
Sbjct: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
Query: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP----PPTRRRRSPSPAPPPRRRRTPTP 575
S S SA+P + S RG R P P + P PPR+ P
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 576 PPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTAS-----PPPPPKRRASPSPP 630
P +P +PSP S +Q + P+ P ++S P P SPS P
Sbjct: 297 GPLSSSPLA-----TPSP---SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP 348
Query: 631 PKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA 690
P + SPP S T SP+L + H SP S PQ + P +A
Sbjct: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-QA 407
Query: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
P + + PP+ A+ SP Q+P+ + + +P P SP Q+ +S
Sbjct: 408 PPSPPASPPLSPLATPSP---QAPNALAVHLLQAPFSPPP-------SPPVQAPFSPPAS 457
Query: 751 RSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
VS S P ++ PP+ +P PS SP P+ + +P P PP
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASP--PMSPSATPPPQAPPP 504
Score = 101 bits (251), Expect = 4e-21
Identities = 147/620 (23%), Positives = 211/620 (34%), Gaps = 97/620 (15%)
Query: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPK-EPSPEK 263
T SR+P+ P + P K S +S +P P+ + S E+
Sbjct: 85 TSSRNPASRPPASGRGERAPP----AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 264 NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYS---PRRRPSPRRR 320
+ K E + RS + +R T +P P RSR+ PR PS R
Sbjct: 141 TVARGKATEAPK-RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS--AR 197
Query: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
P P P + + H + RRR SA +S S S + P P R+
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
Query: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
R T R P+ P+ P PK + P Q RK +S +
Sbjct: 258 SARGTPR------------APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
+ +S +P P ++ SS
Sbjct: 306 TPSPSAALQSQAPPTLP-----------------------------------ATPHSSSL 330
Query: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS--PSPPPTRRR 558
+ + P + + PS A+P + SP + S PSPP
Sbjct: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP----- 385
Query: 559 RSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA--- 615
SP PPP+ PP + PSPP SPP+ +PSP A
Sbjct: 386 LSPLATPPPQAPPALALPPLQAPPSPPA----------SPPLSPLATPSPQAPNALAVHL 435
Query: 616 -----SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
SPPP P +A SPP VS S P ++ P +P L +SP S
Sbjct: 436 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP--SLAAPPLQVPPSPPASPPMSP 493
Query: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
PQ +P P P + PPP A ++P + PSP + +P
Sbjct: 494 SATPPPQ-----APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
Query: 731 K-KIKKAASPSPQSVRRVSSS-RSVSGSP--EPAAKKPPAPPSPVQSQSPSTNWSPAVPV 786
+ A+P PQ+ +++ V SP P + P PP+P S S P + +
Sbjct: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS---GPRLTL 605
Query: 787 KKAKSPTPSPSPPRNSDQEG 806
A P P PS +S G
Sbjct: 606 ALAPGPPPPPSRSPSSTLSG 625
Score = 100 bits (249), Expect = 6e-21
Identities = 168/681 (24%), Positives = 232/681 (34%), Gaps = 113/681 (16%)
Query: 159 KESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
K + KR + RR + P+P S + R RS T+ P PAP +
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-------RSRAAGTEVGLPRPAPSARP 198
Query: 219 KTP-ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277
+ P E P SV S E ++T EPSP + RP
Sbjct: 199 RPPTEGPRKSVS----SASEHSTT----------------EPSPAARRRPSAGGGLQRPA 238
Query: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
SRS S S T SP+ + P R R+ ++ + +P + P + TPPR+ P
Sbjct: 239 SRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 338 HRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS-------PPRKTRRLSP 390
S SP+ + S S++ +S++PP P SS P SP
Sbjct: 297 GPLSSSPL-----------ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
Query: 391 SASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450
SA PP + PSPPATPP + T + T ++ S P S ++ +
Sbjct: 346 SA-PPSLQTLPSPPATPPSQA----TTSLGSPTLQATHSFLP---SPPLSPLATPPPQAP 397
Query: 451 PSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS 510
P+ A P + S +A Q S S P S
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570
+ + PS +A P + P PP SPS PPP+
Sbjct: 458 PPVSPSATPPSQAPPSLAAPP---------------LQVPPSPPASPPMSPSATPPPQ-- 500
Query: 571 RTPTPPPRRRTP----SPPPRRRSPSPRRYSPPIQRRYSPSPP-------PKRRTASPPP 619
PPP P PPP+ P +PP+Q PSPP P +AS P
Sbjct: 501 ---APPPLAAPPLQLAKPPPQ---APPALATPPLQA--LPSPPASFPGQAPFSPSASLPM 552
Query: 620 PPKRRASPSPPP--KRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ 677
P P PP + PP S + R P S P + A P
Sbjct: 553 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 612
Query: 678 PNKRHSPSPRPRAP------QTSSSPPPVRRGASSSPQRRQSPSP-------STRPIRRV 724
P SPS P +++S P RG S P+ + SP + P
Sbjct: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP-AAW 671
Query: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSG-----SPEPAAKKPPAPPSPVQSQSPSTN 779
SR P P + A +P + S G E PAP + SP T+
Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731
Query: 780 WSPAVPVKKAKSPTPSPSPPR 800
A A + + SP R
Sbjct: 732 GGKAAAGAGAGASSRSPKQAR 752
Score = 62.0 bits (149), Expect = 2e-09
Identities = 74/288 (25%), Positives = 101/288 (35%), Gaps = 42/288 (14%)
Query: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRT 581
R P+RSA S R GR R+P T SP P P R T P
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNT----SPGPVSSPGRASGTTRPGPLGQ 131
Query: 582 PSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR--VSHSP 639
R + +R + S +R T+ P P +PSP RR + +
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-----GTPSPAMARRSRAAGTE 186
Query: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP-----RPRAPQTS 694
R +P + R P+ + S+ ST E P P R PS RP + S
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE---PSPAARRRPSAGGGLQRPASRSLS 243
Query: 695 SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS 754
SS P+ A S P R +P P + P+PK ++ P R
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQALRPPQVTPPR--------- 289
Query: 755 GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
K AP S SP SP+ ++ PT P+ P +S
Sbjct: 290 --------KDAAPALGPLSSSPLATPSPSAALQSQAPPT-LPATPHSS 328
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 105 bits (261), Expect = 2e-22
Identities = 173/777 (22%), Positives = 301/777 (38%), Gaps = 109/777 (14%)
Query: 110 LSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER- 168
+S +ENI P+ + K + ++R E +KK E+ K D + SS +K E+
Sbjct: 994 VSKKENIVK-PAKGPQEKVDGERERSPRSEP--PIKKAKEETPKTDNTKSSSSSQKDEKI 1050
Query: 169 SRSPRRRKSRSPSPRRRSSPVRRER-KRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227
+ +PR+ S+S + + PV+ E+ K+ +S+ + + A + EK L
Sbjct: 1051 TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1110
Query: 228 VKVKEPSVQEATST---SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
K K + ++ S +K+ K E + E +PSP++ + + EK P S S
Sbjct: 1111 EKRKRKTEEKGVDKDFESSSMKISKLE-VTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS 1169
Query: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
+ + + +R + S + PS + + ++ + R
Sbjct: 1170 ---------APAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRK 1220
Query: 345 VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404
V SS++L +S+SS+ S P R S T+R +P
Sbjct: 1221 VTGTEGSSSTLVDYTSTSSTGGS-------PVRKSEEKTDTKRTVIKTMEEYNNDNTAPA 1273
Query: 405 A-------TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
P K + + ++ S G+ + V K+ T+ PS K
Sbjct: 1274 EDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPAS-VIKNVSTK----PSNIVKY 1328
Query: 458 RKVELSESEE-DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS-----SSSEDERPKRSH 511
+ E SE+ K K + + +Q + + +SS+ G + S E E P++
Sbjct: 1329 PEKESEPSEKIQKFTKDVSHEIIQH--EVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK 1386
Query: 512 -----VKNGEVGRRRRHSPSRSASPSPRKRQ---KETSPRGRRRRSPSPPPTRRRRSPSP 563
K + R +S S S ++ + K S R + +P ++ +
Sbjct: 1387 NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTR 1446
Query: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
+RR RR SP + S S ++ P +R PK+ T K
Sbjct: 1447 EYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDL-----PKKGTGDSK---KS 1498
Query: 624 RASPS----PPPKRRVSHSPPPKQRSSPVTK-----RRSPSLSSKHRKGSSPSRSTREAR 674
+SPS P + + P + + V K R L +++ K SS ++
Sbjct: 1499 NSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILN 1558
Query: 675 SPQPN----------KRHSPSPRPRAPQTSSSPPPVRRG---ASSSPQRRQSPSPSTRPI 721
P+ + + P+P+ +S + R A+ P +S S S +
Sbjct: 1559 PPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSV 1618
Query: 722 RR------VSRTPEPKKIKKAA-SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
+ +S+ + K ++KA S +V +V SR+ S S SP +S
Sbjct: 1619 KEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSV--------SPSRSH 1670
Query: 775 SPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKH 831
SPS + + +S + S S + D + KKKKKK+ KKHKK KKHKKHKKH
Sbjct: 1671 SPSGS--------QTRSHSSSASSAESQDSK---KKKKKKEKKKHKKHKKHKKHKKH 1716
Score = 85.1 bits (209), Expect = 3e-16
Identities = 150/713 (21%), Positives = 244/713 (34%), Gaps = 137/713 (19%)
Query: 165 KRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELP 224
+ E R RR K S SP SS R S SRS R++S S S + P
Sbjct: 638 REEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSP 697
Query: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
P P + K + RSRSRS
Sbjct: 698 ----------------------------------PYPRRGRGKSRNY-----RSRSRSHG 718
Query: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP------RRMPPP--- 335
R+RSRSP P RR+ SRSRS R SP +R P+ T R +PPP
Sbjct: 719 YHRSRSRSP----PYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDM 774
Query: 336 ----PRHRRSRSPVRRRRRS--------------SASLSGSSSSSSSSRSRSPPKK--PP 375
R R P + R +G+ S++R P++ P
Sbjct: 775 KAYYGRSVDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPL 834
Query: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
+SP + RR R R + + ++++ +PG
Sbjct: 835 NIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDG 894
Query: 436 SG-KVTKHKGTEKRESPSPAPKPRKVELSES-------EEDKGGKMAAADSVQQRRQYRR 487
G K KH+ K E P +E S EE+K + S R
Sbjct: 895 KGNKHKKHRKRRKGEESEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRD 954
Query: 488 QNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR--GR 545
+ + S + S S +D+R + G+ +R+ + S + K K + G
Sbjct: 955 EPMDAESITFKSVSEKDKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGE 1014
Query: 546 RRRSP-SPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604
R RSP S PP ++ + +P T + + S + + +PR+ + +
Sbjct: 1015 RERSPRSEPPIKKAKEETP---------KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEH 1065
Query: 605 SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK--HRK 662
+ P K K+ S ++ ++ K + P+ +K K
Sbjct: 1066 QETKPVKEEKV----------------KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNK 1109
Query: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIR 722
G R T E + + S S V SP+R+ P
Sbjct: 1110 GEKRKRKTEEKGVDKDFESSS---------MKISKLEVTEIVKPSPKRKMEPD-----TE 1155
Query: 723 RVSRTPEPKKIKKAASP-----SPQSVRRVSSSRSVSGSPEPAAK--------KPPAPPS 769
++ RTPE KI +A + ++ +++ S+ ++S + EP+ K K
Sbjct: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
Query: 770 PVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822
V+ + T S + V + + SP R S+++ K+ K +++ D
Sbjct: 1216 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
Score = 64.7 bits (156), Expect = 4e-10
Identities = 150/800 (18%), Positives = 288/800 (36%), Gaps = 81/800 (10%)
Query: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
S+ ++ +R +K + S + S + K + + R R K +
Sbjct: 862 SNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEE-----SEGFLN 916
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVP-KPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR 279
PEL E S K +EP+ E T + +P + + P EP ++ + EK + R R
Sbjct: 917 PELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDK-RER 975
Query: 280 SRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRM---PPPP 336
+ K++ R + ++ + P+ + R SPR P ++ P
Sbjct: 976 DKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
Query: 337 RHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPP--KRTSSPPRKTRRLSPSASP 394
+ +S S ++ + + + + S S+ + P K K+ S K+ +L+
Sbjct: 1036 DNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1095
Query: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTE-KRESPSP 453
++ + + P + R +T + V +S K++K + TE + SP
Sbjct: 1096 AKKPNEKNKPLDNKGEKR-------KRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKR 1148
Query: 454 APKPRKVELSES-EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHV 512
+P ++ + E+DK A A ++ R+ ++ + + S + SE S V
Sbjct: 1149 KMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKV 1208
Query: 513 KNGEV-GRRRRHSPSRSASPSPRKRQKETSPRGRR--RRSPSPPPTRRRRSPSPAPPPRR 569
K +V G+ RR S S TS G R+S T+R +
Sbjct: 1209 KQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1268
Query: 570 RRTPTPPPRRRTPSPPPR------RRSPSPRRYSPPIQRRYSPSPPPKRRTASPP---PP 620
P P + + + PI P+ K + P
Sbjct: 1269 NTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKY 1328
Query: 621 PKRRASPSPPPK---RRVSH-----------------SPPPKQRSSPVTKRRSPSLSSKH 660
P++ + PS + + VSH K R V ++ +P K
Sbjct: 1329 PEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENP---EKR 1385
Query: 661 RKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS--SPQRRQSPSPST 718
+ + P + + R + S S + +TS R ++ +P R + T
Sbjct: 1386 KNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDT 1445
Query: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPST 778
R R E ++ + SP + +S + E K S + SPS
Sbjct: 1446 REYSSSKRRDEKNELTR-RKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPSR 1504
Query: 779 NWSPAVPVKKAKSPTPSPSPPRNS-DQEGGGKKKKKKKDKKHKKDKKHKK--------HK 829
+ P KA T P+ S D+ ++K + ++ K+ K
Sbjct: 1505 DRKP--HDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPET 1562
Query: 830 KHKKEKAVAAAAAAAVTP----AAIAAATTTLAQEEPVAAPEPK-KETESEA------ED 878
+ +KE+ + V P + + ++ L +E AA EP E++SE+ E+
Sbjct: 1563 QVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEE 1622
Query: 879 NLDDLEKHLREKALRSMRKA 898
+ ++ K L++K + +++
Sbjct: 1623 SSGNISKDLKDKIVEKAKES 1642
Score = 57.4 bits (137), Expect = 6e-08
Identities = 135/605 (22%), Positives = 201/605 (33%), Gaps = 134/605 (22%)
Query: 328 PPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
PP +PPP P +R+ P+ R S SR + P P +S+ P
Sbjct: 339 PPPPIPPPRPLIQRNLQPLMR--------------SPISRQQDPLMIPVTSSSTHP---- 380
Query: 387 RLSPSASP-PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
+PS S + +PP + P + +P P + T +SV ++ G + +
Sbjct: 381 --APSISSLTSNQSSLAPPVSGNPSSAPAPVP---DITATVSISVHSEKSDGPF---RDS 432
Query: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
+ + P+ A SE KG A ++ + + Y+ + S G S
Sbjct: 433 DNKILPAAA--------LASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQL 484
Query: 506 RPKRSHVK-------NGEVGRRRRHSPSRSASPSPRKRQKETS------------PRGRR 546
P V+ G G + SP + R+ E S R +R
Sbjct: 485 IPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQR 544
Query: 547 RRSPSPP--PTRRRRSPSPAPPPRRRRTPTPP--------PRRRTPSPPPRRRSPSPRRY 596
+ PS P P P P PP P PP P+ PPP S P +
Sbjct: 545 TQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGF 604
Query: 597 SPPIQRRYSPSPPPKRRTA------SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTK 650
P +P +TA + PP R +R S P SS
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEESKSPYSGSS---Y 661
Query: 651 RRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP-------------RPRA-----PQ 692
RS SK R GS+ SRS + S ++ +S SP R R+ +
Sbjct: 662 SRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHR 721
Query: 693 TSSSPPPVRR--GASSSPQRRQSPSPSTRPI----------RRVSRTPEPKKIKKAASPS 740
+ S PP RR S SPQ + SP+ R + R P P +K S
Sbjct: 722 SRSRSPPYRRYHSRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRS 781
Query: 741 -------------------PQSVRRVSSSRSVSGSPEPAAKKPPAPPS---PVQ-SQSPS 777
+ + + P P+A + P P+ SP
Sbjct: 782 VDFRDPFEKERYREWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPF 841
Query: 778 TNWSPAVPV-------KKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKK 830
T V + S P R+ + K K+K+ + D K KHKK
Sbjct: 842 TRGRREDYVGGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKK 901
Query: 831 HKKEK 835
H+K +
Sbjct: 902 HRKRR 906
Score = 51.6 bits (122), Expect = 3e-06
Identities = 127/639 (19%), Positives = 217/639 (33%), Gaps = 105/639 (16%)
Query: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS-----SSSSRSRSPPKKPPKRTSSPP 382
P + PP R R R + S + SGSS S S SRS S + R+ S
Sbjct: 629 PTTQAPPLSREEFYREQRRLKEESKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRS 688
Query: 383 RKTRRLSPSASPPRR--------RHRPSPPATPPPKTRHSPTPQQSNRTRKSRV--SVSP 432
+R S S PRR R R ++R P + +R+R + SP
Sbjct: 689 H-SRSYSRSPPYPRRGRGKSRNYRSRSRSHGYHRSRSRSPPYRRYHSRSRSPQAFRGQSP 747
Query: 433 GRTS---GKVTKHKGTEKRESPSP----APKPRKVELSESEEDKGGKMAAADSVQQRRQY 485
+ + G+ + RE P P A R V+ + E + + + R+Y
Sbjct: 748 NKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYR-------EWERKY 800
Query: 486 RR------QNQQSSSDSGSSSSSEDERPKR---SHVKNGEVGRRRR--------HSPSRS 528
R + + + S++ E+ P+R +++N R RR H
Sbjct: 801 REWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNI 860
Query: 529 ASPSPRK------RQKETSPRGRRRRSPSPP---------PTRRRR---------SPSPA 564
S P K ++ + + + + S + P R+RR +P
Sbjct: 861 GSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFLNPELL 920
Query: 565 PPPRRRRTPTPPPRRRTPS--PPPRRRSPSPRRYSP------------PIQRRYSPSPPP 610
R+ R PT +T S P R +P R P +R P
Sbjct: 921 ETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKA 980
Query: 611 K------RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664
K + S + P+ P+ +V RS P K+ S
Sbjct: 981 KGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTKS 1040
Query: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGAS---------SSPQRRQSPS 715
S S E + P K HS S + V++ S + ++ + P+
Sbjct: 1041 SSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPN 1100
Query: 716 PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775
+P+ + K +K +S S V+ +P+ K+ P + ++
Sbjct: 1101 EKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRT 1160
Query: 776 PSTN-WSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKE 834
P + S + P KK K + +++ K+ +K + K K+ K K K
Sbjct: 1161 PEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEK--VKGKVR 1218
Query: 835 KAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETE 873
+ V ++ T + +T+ PV E K +T+
Sbjct: 1219 RKVTGTEGSSST--LVDYTSTSSTGGSPVRKSEEKTDTK 1255
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 105 bits (261), Expect = 2e-22
Identities = 173/777 (22%), Positives = 301/777 (38%), Gaps = 109/777 (14%)
Query: 110 LSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRER- 168
+S +ENI P+ + K + ++R E +KK E+ K D + SS +K E+
Sbjct: 1028 VSKKENIVK-PAKGPQEKVDGERERSPRSEP--PIKKAKEETPKTDNTKSSSSSQKDEKI 1084
Query: 169 SRSPRRRKSRSPSPRRRSSPVRRER-KRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227
+ +PR+ S+S + + PV+ E+ K+ +S+ + + A + EK L
Sbjct: 1085 TGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1144
Query: 228 VKVKEPSVQEATST---SDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKS 284
K K + ++ S +K+ K E + E +PSP++ + + EK P S S
Sbjct: 1145 EKRKRKTEEKGVDKDFESSSMKISKLE-VTEIVKPSPKRKMEPDTEKMDRTPEKDKISLS 1203
Query: 285 RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSP 344
+ + + +R + S + PS + + ++ + R
Sbjct: 1204 ---------APAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRK 1254
Query: 345 VRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP 404
V SS++L +S+SS+ S P R S T+R +P
Sbjct: 1255 VTGTEGSSSTLVDYTSTSSTGGS-------PVRKSEEKTDTKRTVIKTMEEYNNDNTAPA 1307
Query: 405 A-------TPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
P K + + ++ S G+ + V K+ T+ PS K
Sbjct: 1308 EDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPAS-VIKNVSTK----PSNIVKY 1362
Query: 458 RKVELSESEE-DKGGKMAAADSVQQRRQYRRQNQQSSSDSGSS-----SSSEDERPKRSH 511
+ E SE+ K K + + +Q + + +SS+ G + S E E P++
Sbjct: 1363 PEKESEPSEKIQKFTKDVSHEIIQH--EVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK 1420
Query: 512 -----VKNGEVGRRRRHSPSRSASPSPRKRQ---KETSPRGRRRRSPSPPPTRRRRSPSP 563
K + R +S S S ++ + K S R + +P ++ +
Sbjct: 1421 NSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTR 1480
Query: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
+RR RR SP + S S ++ P +R PK+ T K
Sbjct: 1481 EYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDL-----PKKGTGDSK---KS 1532
Query: 624 RASPS----PPPKRRVSHSPPPKQRSSPVTK-----RRSPSLSSKHRKGSSPSRSTREAR 674
+SPS P + + P + + V K R L +++ K SS ++
Sbjct: 1533 NSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILN 1592
Query: 675 SPQPN----------KRHSPSPRPRAPQTSSSPPPVRRG---ASSSPQRRQSPSPSTRPI 721
P+ + + P+P+ +S + R A+ P +S S S +
Sbjct: 1593 PPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSV 1652
Query: 722 RR------VSRTPEPKKIKKAA-SPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQ 774
+ +S+ + K ++KA S +V +V SR+ S S SP +S
Sbjct: 1653 KEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSV--------SPSRSH 1704
Query: 775 SPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKH 831
SPS + + +S + S S + D + KKKKKK+ KKHKK KKHKKHKKH
Sbjct: 1705 SPSGS--------QTRSHSSSASSAESQDSK---KKKKKKEKKKHKKHKKHKKHKKH 1750
Score = 92.4 bits (228), Expect = 2e-18
Identities = 163/754 (21%), Positives = 267/754 (35%), Gaps = 144/754 (19%)
Query: 126 LKKEEI--KQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPR 183
L +EE +QR++++E+ K DE + KE E + ++ER RR SRS SP
Sbjct: 636 LSREEFYREQRRLKEEE-KKKSKLDEFTNDFAKELMEYKKIQKER----RRSFSRSKSPY 690
Query: 184 RRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSD 243
SS R S SRS R++S S S + P
Sbjct: 691 SGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSP------------------- 731
Query: 244 ILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR 303
P P + K + RSRSRS R+RSRSP P RR+
Sbjct: 732 ---------------PYPRRGRGKSRNY-----RSRSRSHGYHRSRSRSP----PYRRYH 767
Query: 304 SRSRSYSPRRRPSPRRRPSPRRRTPP------RRMPPP-------PRHRRSRSPVRRRRR 350
SRSRS R SP +R P+ T R +PPP R R P + R
Sbjct: 768 SRSRSPQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERY 827
Query: 351 S--------------SASLSGSSSSSSSSRSRSPPKK--PPKRTSSPPRKTRRLSPSASP 394
+G+ S++R P++ P +SP + RR
Sbjct: 828 REWERKYREWYEKYYKGYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQ 887
Query: 395 PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG-KVTKHKGTEKRESPSP 453
R R + + ++++ +PG G K KH+ K E
Sbjct: 888 SHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEG 947
Query: 454 APKPRKVELSES-------EEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER 506
P +E S EE+K + S R + + S + S S +D+R
Sbjct: 948 FLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKR 1007
Query: 507 PKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR--GRRRRSP-SPPPTRRRRSPSP 563
+ G+ +R+ + S + K K + G R RSP S PP ++ + +P
Sbjct: 1008 ERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETP 1067
Query: 564 APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR 623
T + + S + + +PR+ + + + P K
Sbjct: 1068 ---------KTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKV-------- 1110
Query: 624 RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK--HRKGSSPSRSTREARSPQPNKR 681
K+ S ++ ++ K + P+ +K KG R T E + +
Sbjct: 1111 --------KKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFES 1162
Query: 682 HSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP-- 739
S S V SP+R+ P ++ RTPE KI +A
Sbjct: 1163 SS---------MKISKLEVTEIVKPSPKRKMEPD-----TEKMDRTPEKDKISLSAPAKK 1208
Query: 740 ---SPQSVRRVSSSRSVSGSPEPAAK--------KPPAPPSPVQSQSPSTNWSPAVPVKK 788
+ ++ +++ S+ ++S + EP+ K K V+ + T S + V
Sbjct: 1209 IKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDY 1268
Query: 789 AKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKD 822
+ + SP R S+++ K+ K +++ D
Sbjct: 1269 TSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNND 1302
Score = 53.5 bits (127), Expect = 9e-07
Identities = 115/481 (23%), Positives = 167/481 (34%), Gaps = 93/481 (19%)
Query: 328 PPRRMPPP-PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTR 386
PP +PPP P +R+ P+ R S SR + P P +S+ P
Sbjct: 339 PPPPIPPPRPLIQRNLQPLMR--------------SPISRQQDPLMIPVTSSSTHP---- 380
Query: 387 RLSPSASP-PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
+PS S + +PP + P + +P P + T +SV ++ G + +
Sbjct: 381 --APSISSLTSNQSSLAPPVSGNPSSAPAPVP---DITATVSISVHSEKSDGPF---RDS 432
Query: 446 EKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDE 505
+ + P+ A SE KG A ++ + + Y+ + S G S
Sbjct: 433 DNKILPAAA--------LASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQL 484
Query: 506 RPKRSHVK-------NGEVGRRRRHSPSRSASPSPRKRQKETS------------PRGRR 546
P V+ G G + SP + R+ E S R +R
Sbjct: 485 IPTTGPVRINTARPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQR 544
Query: 547 RRSPSPP--PTRRRRSPSPAPPPRRRRTPTPP--------PRRRTPSPPPRRRSPSPRRY 596
+ PS P P P P PP P PP P+ PPP S P +
Sbjct: 545 TQGPSLPATPVFVPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGF 604
Query: 597 SPPIQRRYSPSPPPKRRTASPPPPPKRRASPSP-----PPKRRVSHSPPPKQRSSPVT-- 649
P +P +TA P +A P +RR+ K + T
Sbjct: 605 PPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTND 664
Query: 650 --------------KRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS-----PRPRA 690
+RRS S S GSS SRS+ + S S R +
Sbjct: 665 FAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHS 724
Query: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSS 750
S SPP RRG S R S S S R SR+P P + + S SPQ+ R S +
Sbjct: 725 RSYSRSPPYPRRGRGKSRNYR-SRSRSHGYHRSRSRSP-PYRRYHSRSRSPQAFRGQSPN 782
Query: 751 R 751
+
Sbjct: 783 K 783
Score = 51.2 bits (121), Expect = 4e-06
Identities = 142/687 (20%), Positives = 223/687 (32%), Gaps = 129/687 (18%)
Query: 221 PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-PEKNSKKEKEKEKTR---- 275
P P + P V T+ +P + P +E E+ KE+EK+K++
Sbjct: 602 PGFPPAPANLSTPWVSSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEF 661
Query: 276 --------------PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRP 321
+ R RS SRS++ S++R + S+SRS S R R R
Sbjct: 662 TNDFAKELMEYKKIQKERRRSFSRSKSPYSGSSYSRSSYTY-SKSRSGSTRSRSYSRSFS 720
Query: 322 SPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSP 381
R+ R PP PR R +S R R S SRSRSPP + S
Sbjct: 721 RSHSRSYSRS-PPYPRRGRGKSRNYRSR-------SRSHGYHRSRSRSPPYRRYHSRSRS 772
Query: 382 PRKTRRLSPSA-----SPPRRRHRPSPPATPPP---KTRHSPTPQQSNRTRKSRVSVSPG 433
P+ R SP+ R + PPP K + + + K R
Sbjct: 773 PQAFRGQSPNKRNVPQGETEREYFNRYREVPPPYDMKAYYGRSVDFRDPFEKERYREWER 832
Query: 434 RTSGKVTKH-KGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS 492
+ K+ KG P P+ E E + + + RR+ Q
Sbjct: 833 KYREWYEKYYKGYAAGAQPRPSANR---ENFSPERFLPLNIRNSPFTRGRREDYVGGQSH 889
Query: 493 SSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552
S + S+ E + H + + + S + +P K K R RR+ S
Sbjct: 890 RSRNIGSNYPEKLSARDGHNQKDNTKSKEKESEN---APGDGKGNKHKKHRKRRKGEES- 945
Query: 553 PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS--PPPRRRSPSPRRYSPPIQRRYSPSPPP 610
+P R+ R PT +T S P R +P R P +
Sbjct: 946 ---EGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFK--- 999
Query: 611 KRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRST 670
S S KR PK + ++ S SK P++
Sbjct: 1000 ---------------SVSEKDKRE---RDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGP 1041
Query: 671 REARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730
+E + R R+P+ S PP+++ TP+
Sbjct: 1042 QEKVDGE---------RERSPR---SEPPIKKAKEE--------------------TPKT 1069
Query: 731 KKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAK 790
K ++S ++G+P A K S + Q PVK+ K
Sbjct: 1070 DNTKSSSSS--------QKDEKITGTPRKAHSK-----SAKEHQETK-------PVKEEK 1109
Query: 791 SPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAI 850
++ +K KK +K D K +K K+ +EK V ++ +
Sbjct: 1110 VKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISK 1169
Query: 851 AAATTTLAQEEPVAAPEPKKETESEAE 877
T + P PK++ E + E
Sbjct: 1170 LEVT-------EIVKPSPKRKMEPDTE 1189
Score = 45.8 bits (107), Expect = 2e-04
Identities = 84/363 (23%), Positives = 125/363 (34%), Gaps = 94/363 (25%)
Query: 555 TRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614
T+R R P PPP P PPPR P +R+ P SP I R+ P P +
Sbjct: 329 TKRLRKQLPPPPP-----PIPPPR------PLIQRNLQPLMRSP-ISRQQDPLMIPVTSS 376
Query: 615 ASPPPPP-----KRRASPSPPPKRRVSHSPPPKQ-------------------RSSPVTK 650
++ P P ++S +PP S +P P R S
Sbjct: 377 STHPAPSISSLTSNQSSLAPPVSGNPSSAPAPVPDITATVSISVHSEKSDGPFRDSDNKI 436
Query: 651 RRSPSLSSKHRKGSSPSRSTR--EARSPQPNKRHSPS----------------------P 686
+ +L+S+H KG+S T E + Q +PS
Sbjct: 437 LPAAALASEHSKGTSSIAITALMEEKGYQVPVLGTPSLLGQSLLHGQLIPTTGPVRINTA 496
Query: 687 RPRAPQTS-----------SSPPPVRRGA-------------SSSPQRRQSPSPSTRPIR 722
RP + S P +RRG S QR Q PS P+
Sbjct: 497 RPGGGRPGWEHSNKLGYLVSPPQQIRRGERSCYRSINRGRHHSERSQRTQGPSLPATPVF 556
Query: 723 RVSRTPEPKKIKKAASPSPQSVRRVS-SSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNW- 780
P P P V S + G P PA P P P + ST W
Sbjct: 557 VPVPPPPLYPPPPHTLPLPPGVPPPQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWV 616
Query: 781 SPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKK--------DKKHKKHKKHK 832
S V + + + +PP + ++ +++ K+++KK K K+ ++KK +
Sbjct: 617 SSGVQTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQ 676
Query: 833 KEK 835
KE+
Sbjct: 677 KER 679
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 104 bits (259), Expect = 4e-22
Identities = 112/549 (20%), Positives = 198/549 (36%), Gaps = 45/549 (8%)
Query: 149 EDKDKRDKEEKESSREKRERSR-SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS 207
+D+++ ++E+E REKR+ R + R+R+ R R R RER+R + +T
Sbjct: 52 DDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDR 111
Query: 208 RSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKK 267
+++ + E + + E T +E +++++K
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQ--------------RERERQRDAEK 157
Query: 268 EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR- 326
E+E++ R R R ++R + R R + R R R R + R S R R R R
Sbjct: 158 ERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERE 217
Query: 327 --TPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384
T R R R + R R A +S + ++ R +K
Sbjct: 218 TETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQK 277
Query: 385 TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444
R RR R + R ++ NR R+ R + T+
Sbjct: 278 ERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDR 337
Query: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
++RE + R+ E+ + G+ + ++R + R +++QS+ + D
Sbjct: 338 EKERE----RKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRD 393
Query: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKE-TSPRGRRRRSPSPPPTRRRRSPSP 563
++ + E R + + R+R+K+ S RGR R R R
Sbjct: 394 RDRQKERERQTEKDRDGQRETEKQ-----REREKDRESERGRER-------GREREKQKG 441
Query: 564 APPPRRRRTPTPPPRRRTPS-----PPPRRR-----SPSPRRYSPPIQRRYSPSPPPKRR 613
R R+T R+R S PPPR P R + I+ + SP P
Sbjct: 442 RERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAAS 501
Query: 614 TASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREA 673
T P P + + +RR K+ +R S +++ +PS
Sbjct: 502 TRFPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPR 561
Query: 674 RSPQPNKRH 682
+P KR+
Sbjct: 562 YTPGDGKRN 570
Score = 101 bits (251), Expect = 4e-21
Identities = 111/517 (21%), Positives = 182/517 (35%), Gaps = 33/517 (6%)
Query: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204
+K+ E + ++ + E+E+ R++ R R RK R+R RER+ R R R
Sbjct: 59 QKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD-RQR 117
Query: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN 264
K R+ +++E+ E + ++ Q + + ++ E+N
Sbjct: 118 EKERN---RQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 265 SKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT-RPRRRHRSRSRSYSPRRRPSPRRRPSP 323
+KE+E+EK R R R + R + H+ R R R R R R+ R
Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDR 234
Query: 324 RRRTPPRRMPPPPRHRRSRSPVRR--RRRSSASLSGSSSSSSSSRSRSPPKKPPKR---- 377
+R+T R R R S R R R R +K +R
Sbjct: 235 QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERD 294
Query: 378 --TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
T + R R+R R + R + ++ R RK + R
Sbjct: 295 RETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRE 354
Query: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
+ T +G + E + R + + E++ D + R++ R + + D
Sbjct: 355 RNRQTGREGRRQAERERERERERDRQSAREREER-----ERDRDRDRQKERERQTEKDRD 409
Query: 496 SGSSSSSEDERPK-RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSP---S 551
+ + ER K R + E GR R R R+RQ + +R+RS +
Sbjct: 410 GQRETEKQREREKDRESERGRERGREREKQKGRERD---RERQTDRQAGRQRKRSTLYVN 466
Query: 552 PPPTRRRRSPSPAPPPRRRR------TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYS 605
PPP R + P R R +P P T P R S R + +RR+
Sbjct: 467 PPPRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAG--RRRWE 524
Query: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK 642
P KR P P + S P P+
Sbjct: 525 PRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPR 561
Score = 88.2 bits (217), Expect = 3e-17
Identities = 102/466 (21%), Positives = 171/466 (36%), Gaps = 32/466 (6%)
Query: 128 KEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSS 187
+E +QR+ E+ + +++ E + +R ++ + + +RER R + + R + R R
Sbjct: 111 RERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ-TDRERQR 169
Query: 188 PVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKV 247
R R++ R ++R + R EK+ KT + + +E + T T +
Sbjct: 170 QTERNRQKERERE-KNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQT 228
Query: 248 PKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSH-------TRPRR 300
+ E EK +++E+ E+ R + R + R R R R R R+
Sbjct: 229 DRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQ 288
Query: 301 RHRSRSRSYSPRR-RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVR-------RRRRSS 352
R R R +R R R R R R R R R R R+R+
Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQ 348
Query: 353 ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
+ + + R ++ +R R++ R R R R K R
Sbjct: 349 TEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDR 408
Query: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKV-TKHKGTEK-RESPSPAPKPRKVELSESEEDKG 470
+ R R+ GR G+ K KG E+ RE + R+ + S +
Sbjct: 409 DGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPP 468
Query: 471 GKMAAADSVQQ--RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRS 528
+ A + VQ R R +SS + ++S+ + + G V RRR P
Sbjct: 469 PRTARSGVVQSDPNRPTRGIRWKSSPEDPKAASTRFPWGRPAKASRGRVAGRRRWEP--- 525
Query: 529 ASPSPRKRQKETSPRGRRRRSPSPP-PTRRRRSPSPAPPPRRRRTP 573
R E +G R PS T S +P+ P R TP
Sbjct: 526 -------RLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGPRYTP 564
Score = 85.1 bits (209), Expect = 3e-16
Identities = 110/537 (20%), Positives = 180/537 (33%), Gaps = 33/537 (6%)
Query: 262 EKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRS-YSPRRRPSPRRR 320
E+N +KE+E+ + + R R R R R R R R RHR R R R R + R R
Sbjct: 55 ERNRQKERERRREK-RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRER 113
Query: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380
R + R+ R R R+ + R R ++ ++T
Sbjct: 114 DRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTER 173
Query: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
+K R + R R R + RHS ++ R R++ R + +
Sbjct: 174 NRQKEREREKNRQERRERERQREKEN-KTEDRHSERGRERERERETETETERKRQTDRER 232
Query: 441 KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSS 500
+ +RE A + R E + + + D + RRQ R+ Q +
Sbjct: 233 DRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE 292
Query: 501 SSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRS 560
+ KR + E R R R R+R++E R R+R + R R
Sbjct: 293 RDRETERKRERQRERERERERNRKRERE-----RERERE---RERQRETERDREKERERK 344
Query: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
R+R+T R R RR++ R R+ + + R
Sbjct: 345 -------RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD------ 391
Query: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARS-PQPN 679
R + R + QR + + R S+ + R ++ R +
Sbjct: 392 ---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRER 448
Query: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP 739
+ + R R T PP R S Q S RP R + P+ K A++
Sbjct: 449 QTDRQAGRQRKRSTLYVNPPPRTARSGVVQ-----SDPNRPTRGIRWKSSPEDPKAASTR 503
Query: 740 SPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSP 796
P +S V+G + + + PS + P+ +A S P P
Sbjct: 504 FPWGRPAKASRGRVAGRRRWEPRLGEKRGQGGEGRRPSGGFGTENPLSQAPSVFPGP 560
Score = 84.7 bits (208), Expect = 3e-16
Identities = 95/419 (22%), Positives = 159/419 (37%), Gaps = 32/419 (7%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRR 184
E +++ + RQ E+E+ + +++ E + +R+KE K R R R++ + + R+
Sbjct: 166 ERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERK 225
Query: 185 RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDI 244
R + R+R+R R + + S +++K E + ++ +E +D
Sbjct: 226 RQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 245 LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304
+ + E E E E+ ++E+E+E+ R R R R + R R R R R + R R
Sbjct: 286 KRQRRTERDRE-TERKRERQRERERERERNRKRERERERERERERQRETERDREKERERK 344
Query: 305 RSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSS 364
R R R + + RR+ R R R+S R R
Sbjct: 345 RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERD------RDRDRQK 398
Query: 365 SRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTR 424
R R K + + ++ R + R R R + R T +Q+ R R
Sbjct: 399 ERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQR 458
Query: 425 K-SRVSVS-PGRT--SGKVTKH-----KGTEKRESPSPAPKPRKVELSESEEDKGGKMAA 475
K S + V+ P RT SG V +G + SP PK K A+
Sbjct: 459 KRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPED-PKAASTRFPWGRPAK----AS 513
Query: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534
V RR++ + + G E RP +G G S + S P PR
Sbjct: 514 RGRVAGRRRWEPRLGEKRGQGG-----EGRRP------SGGFGTENPLSQAPSVFPGPR 561
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 103 bits (257), Expect = 7e-22
Identities = 182/767 (23%), Positives = 267/767 (34%), Gaps = 148/767 (19%)
Query: 121 SAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSP 180
+A LE E + I E +AS+ D + ++ E E SR +S S K S
Sbjct: 159 AAELEEASAESEDEMIHPEGVASLLPPDF-QSSLERPELELSRHSPRKSSSISEEKGDSD 217
Query: 181 SPR-----RRSSPVRRER--KRSHSRSPRHR-----TKSRSPSPAPEKKEKTPELPEPSV 228
+ RRSS VR+ R K S P T SR+ ++ KT E E
Sbjct: 218 DEKPRKGERRSSRVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLKTEEEEEEEE 277
Query: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRT 288
+ +E +E + K + + E KE E K +E RP++RS+ +
Sbjct: 278 EEEEDD-EEEEGDDEGQKSREAPILKEFKEEGEEIPRVKPEEMMDERPKTRSQEQEVLER 336
Query: 289 RSR-SPSHTRPRRRHRSRSRSYSPRRRPSP-----RRRPSPRRRTPPRRMPPPPRHRRSR 342
R + S R+ H +R + + SP R S + + P PPR R
Sbjct: 337 GGRFTRSQEEARKSHLARQQQEKEMKTTSPLEEEEREIKSSQGLKEKSKSPSPPRLTEDR 396
Query: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRP- 401
++ S +L ++S +PP K SSPP + S P P
Sbjct: 397 -----KKASLVALP----EQTASEEETPPPLLTKEASSPPPHPQLHSEEEIEPMEGPAPP 447
Query: 402 -----SPPATPP-------------------PKTRHSPTPQQSNRTRKSRVSVSP---GR 434
SPP T P + S T +S + SV P
Sbjct: 448 VLIQLSPPNTDADTRELLVSQHTVQLVGGLSPLSSPSDTKAESPAEKVPEESVLPLVQKS 507
Query: 435 TSGKVTKHKGTEKRESPSPAPKPRKVE-------------LSESEEDKGGKMAAADSVQQ 481
T + K E S P P K+E S E K G+ A+ +
Sbjct: 508 TLADYSAQKDLEPESDRSAQPLPLKIEELALAKGITEECLKQPSLEQKEGRRASHTLLPS 567
Query: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
R + + SS S SSSSS RS ++ + R HSP RS + + +
Sbjct: 568 HRLKQSADSSSSRSSSSSSSSS-----RSRSRSPDSSGSRSHSPLRSKQRDVAQARTHAN 622
Query: 542 PRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ 601
PRGR P+ T R R+ S S S + SP +
Sbjct: 623 PRGR---------------------PKMGSRSTSESRSRSRSRSRSASSNSRKSLSPGVS 661
Query: 602 RRYSPS------PPPKRRTASPPPP------PKRRASPSPP--PKRRVSHSPPPKQRSSP 647
R S S P + A+PP P PK R S S RR+S P+
Sbjct: 662 RDSSTSYTETKDPSSGQEVATPPVPQLQVCEPKERTSTSSSSVQARRLSQ---PESAEKH 718
Query: 648 VTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSS 707
VT+R P +GS EA P + +P+ +T +S P +
Sbjct: 719 VTQRLQP------ERGSPKKCEAEEAEPP-------AATQPQTSETQTSHLPESERIHHT 765
Query: 708 PQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767
+ ++ + T R + PEP P P +VS+ GS E KK +
Sbjct: 766 VEEKEEVTMDTSENRPENDVPEP--------PMP-IADQVSNDDRPEGSVEDEEKKESSL 816
Query: 768 PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKK 814
P + + + + VP NSD EGG +K++
Sbjct: 817 PKSFKRKISVVSATKGVPA-------------GNSDTEGGQPGRKRR 850
Score = 74.3 bits (181), Expect = 5e-13
Identities = 64/215 (29%), Positives = 94/215 (43%), Gaps = 23/215 (10%)
Query: 145 KKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHR 204
+++ E + E+E E+RER+RS R + R P R RS SR R +
Sbjct: 1135 QREQERAVREQWAEREREMERRERTRSEREWDR----DKVREGP----RSRSRSRDRRRK 1186
Query: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN 264
+++S EKKEK E EP K+ + ++ + I +P + KE +
Sbjct: 1187 ERAKSKEKKSEKKEKAQE--EPPAKLLDDLFRKTKAAPCIYWLPLTDSQIVQKEAERAER 1244
Query: 265 SKK--------EKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPS 316
+K+ E+E++K R + R ++R R + H+R R R R R R R
Sbjct: 1245 AKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDR 1304
Query: 317 PRRRPSPRRRTPPRRMPPPPRHRRSRS---PVRRR 348
R R R R RR RH RSRS PVR R
Sbjct: 1305 DRERDRERGRERDRR--DTKRHSRSRSRSTPVRDR 1337
Score = 44.3 bits (103), Expect = 5e-04
Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 9/100 (9%)
Query: 123 FLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREK---RERSRSPRRRKSRS 179
+L L +I Q++ E+ + A K+ E + K +EE++ REK RER+R R K R
Sbjct: 1226 WLPLTDSQIVQKEAERAERA---KEREKRRKEQEEEEQKEREKEAERERNRQLEREKRRE 1282
Query: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK 219
S R RER+R R R R + R E+ +
Sbjct: 1283 HS---RERDRERERERERDRGDRDRDRERDRERGRERDRR 1319
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/89 (32%), Positives = 48/89 (53%), Gaps = 4/89 (4%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSRE-KRERSRSPRRRKSRSPSPR 183
E KE K+R+ ++E+ ++++ ++++ + E+E RE RER R R + R R
Sbjct: 1243 ERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDR 1302
Query: 184 RRSSPVRRERKRSHSR--SPRH-RTKSRS 209
R RER R R + RH R++SRS
Sbjct: 1303 DRDRERDRERGRERDRRDTKRHSRSRSRS 1331
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/94 (28%), Positives = 42/94 (44%), Gaps = 2/94 (2%)
Query: 245 LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS-RSPSHTRPRRRHR 303
L P P P+ P+ P E+ ++ +E+ R R + R RTRS R + R R
Sbjct: 1117 LHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMER-RERTRSEREWDRDKVREGPR 1175
Query: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPR 337
SRSRS RR+ + + + + PP +
Sbjct: 1176 SRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAK 1209
Score = 39.7 bits (91), Expect = 0.013
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 2/81 (2%)
Query: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKE-EKESSREKRERSRSPRRRKSRSPSPR 183
E +KE K+ + E+ + +K+ E +RD+E E+E R++ +R R R + R
Sbjct: 1258 EEQKEREKEAERERNRQLEREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERD 1317
Query: 184 RRSSPVRRERKRSHSRSPRHR 204
RR + R R RS S R R
Sbjct: 1318 RRDTK-RHSRSRSRSTPVRDR 1337
Score = 37.7 bits (86), Expect = 0.049
Identities = 53/236 (22%), Positives = 77/236 (32%), Gaps = 44/236 (18%)
Query: 366 RSRSPPKKPPKRTSSPPRKTRRLSPSA----------SPPRRRHRPSPPATPPPKTRHSP 415
R PP PP + PR +R A RR S K R P
Sbjct: 1115 RPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGP 1174
Query: 416 TPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVE-------------- 461
+ +R R+ R +K K +EK+E P + ++
Sbjct: 1175 RSRSRSRDRR--------RKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYW 1226
Query: 462 LSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDER-------PKRSHVKN 514
L ++ K A + R+ RR+ Q+ +E ER +R H +
Sbjct: 1227 LPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRE 1286
Query: 515 GEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570
+ R R R R+R +E RGR R R RS S + P R R
Sbjct: 1287 RDRERERERERDRGDRDRDRERDRE---RGRER--DRRDTKRHSRSRSRSTPVRDR 1337
Score = 37.0 bits (84), Expect = 0.083
Identities = 51/248 (20%), Positives = 90/248 (36%), Gaps = 42/248 (16%)
Query: 293 PSHTRPRRRHRSRS--RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRR 350
P H R +R + R+ ++ R R RR + R R RSRS RRR+
Sbjct: 1128 PQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREGPRSRSRSRDRRRKE 1187
Query: 351 SSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPK 410
+ S S + ++ + P K RKT + +P P
Sbjct: 1188 RAK----SKEKKSEKKEKAQEEPPAKLLDDLFRKT--------------KAAPCIYWLPL 1229
Query: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKG 470
T +++ R ++ K + ++E K R+ E+E ++
Sbjct: 1230 TDSQIVQKEAERAERA--------------KEREKRRKEQEEEEQKERE---KEAERERN 1272
Query: 471 GKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR--RRHSPSRS 528
++ + ++R R ++++ + D +R + E RR +RHS SRS
Sbjct: 1273 RQL---EREKRREHSRERDRERERERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRS 1329
Query: 529 ASPSPRKR 536
S R R
Sbjct: 1330 RSTPVRDR 1337
Score = 34.7 bits (78), Expect = 0.41
Identities = 47/221 (21%), Positives = 72/221 (32%), Gaps = 43/221 (19%)
Query: 395 PRRRHRPSPPATPPPKTRHSPTPQQS-----------------NRTRKSRVSVSPGRTSG 437
PR H P PP PP+ + +Q RTR R G
Sbjct: 1114 PRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVREG 1173
Query: 438 KVTKHKGTEKRESPSPAPKPRKVELSE-SEEDKGGK-----------------MAAADSV 479
++ + ++R K +K E E ++E+ K + DS
Sbjct: 1174 PRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTDSQ 1233
Query: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR------RRRHSPSRSASPSP 533
+++ R + + E+E+ +R E R RR HS R
Sbjct: 1234 IVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRREHSRERDRE-RE 1292
Query: 534 RKRQKETSPRGR-RRRSPSPPPTRRRRSPSPAPPPRRRRTP 573
R+R+++ R R R R R RR R R TP
Sbjct: 1293 RERERDRGDRDRDRERDRERGRERDRRDTKRHSRSRSRSTP 1333
Score = 32.3 bits (72), Expect = 2.0
Identities = 32/170 (18%), Positives = 59/170 (34%), Gaps = 27/170 (15%)
Query: 755 GSPEPAAKKPPAPPSPVQ---------SQSPSTNWSPAVPVKKAKSPTPSPSP------- 798
G P P PP P P Q ++ W+ + + T S
Sbjct: 1112 GIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERTRSEREWDRDKVR 1171
Query: 799 --PRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKK---------HKKEKAVAAAAAAAVTP 847
PR+ + ++K++ K K+ K +KK K ++ +K KA +T
Sbjct: 1172 EGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLLDDLFRKTKAAPCIYWLPLTD 1231
Query: 848 AAIAAATTTLAQEEPVAAPEPKKETESEAEDNLDDLEKHLREKALRSMRK 897
+ I A+ K++ E E ++ + E+ + R R+
Sbjct: 1232 SQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERERNRQLEREKRR 1281
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.122 0.345
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,111,631
Number of Sequences: 37866
Number of extensions: 4281615
Number of successful extensions: 144420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1649
Number of HSP's successfully gapped in prelim test: 3420
Number of HSP's that attempted gapping in prelim test: 28383
Number of HSP's gapped (non-prelim): 48154
length of query: 904
length of database: 18,247,518
effective HSP length: 111
effective length of query: 793
effective length of database: 14,044,392
effective search space: 11137202856
effective search space used: 11137202856
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.