Guide to the Human Genome
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Search of human proteins with 42490758

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42490758 cell division cycle 25A isoform a [Homo sapiens]
         (524 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42490758 cell division cycle 25A isoform a [Homo sapiens]         1075   0.0  
gi|42490760 cell division cycle 25A isoform b [Homo sapiens]          973   0.0  
gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]           407   e-113
gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]          406   e-113
gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]          388   e-108
gi|125625350 cell division cycle 25C isoform a [Homo sapiens]         255   6e-68
gi|12408658 cell division cycle 25C isoform b [Homo sapiens]          255   6e-68
gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo ...    48   2e-05
gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo ...    48   2e-05
gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo s...    48   2e-05
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]     37   0.044
gi|40538736 RAN binding protein 10 [Homo sapiens]                      36   0.075
gi|197245440 hypothetical protein LOC23285 [Homo sapiens]              35   0.22 
gi|162287219 prune homolog 2 [Homo sapiens]                            33   0.49 
gi|169179759 PREDICTED: hypothetical protein [Homo sapiens]            32   1.1  
gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog...    32   1.1  
gi|169180158 PREDICTED: hypothetical protein [Homo sapiens]            32   1.4  
gi|55741677 SET domain containing 1A [Homo sapiens]                    32   1.9  
gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]    31   2.4  
gi|22748641 CHMP family, member 7 [Homo sapiens]                       31   2.4  
gi|169183882 PREDICTED: hypothetical protein [Homo sapiens]            31   3.2  
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              31   3.2  
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    30   4.1  
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    30   4.1  
gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]           30   5.4  
gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]             30   5.4  
gi|8659574 transcription factor E3 [Homo sapiens]                      30   5.4  
gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Hom...    30   5.4  
gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]     30   7.0  
gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]      30   7.0  

>gi|42490758 cell division cycle 25A isoform a [Homo sapiens]
          Length = 524

 Score = 1075 bits (2780), Expect = 0.0
 Identities = 524/524 (100%), Positives = 524/524 (100%)

Query: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60
           MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
Sbjct: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60

Query: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120
           QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
Sbjct: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120

Query: 121 RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP 180
           RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP
Sbjct: 121 RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP 180

Query: 181 ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 240
           ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
Sbjct: 181 ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 240

Query: 241 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 300
           WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
Sbjct: 241 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 300

Query: 301 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 360
           ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
Sbjct: 301 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 360

Query: 361 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 420
           SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
Sbjct: 361 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 420

Query: 421 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 480
           DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
Sbjct: 421 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 480

Query: 481 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 524
           CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
Sbjct: 481 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 524


>gi|42490760 cell division cycle 25A isoform b [Homo sapiens]
          Length = 484

 Score =  973 bits (2516), Expect = 0.0
 Identities = 484/524 (92%), Positives = 484/524 (92%), Gaps = 40/524 (7%)

Query: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60
           MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE
Sbjct: 1   MELGPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNLTVTMDQLQGLGSDYE 60

Query: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120
           QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK
Sbjct: 61  QPLEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALK 120

Query: 121 RSHSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAP 180
           RSHSDSLDHDIFQLIDPDENKEN                                     
Sbjct: 121 RSHSDSLDHDIFQLIDPDENKEN------------------------------------- 143

Query: 181 ARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 240
              LSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL
Sbjct: 144 ---LSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMASL 200

Query: 241 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 300
           WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK
Sbjct: 201 WTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPK 260

Query: 301 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 360
           ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI
Sbjct: 261 ESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYI 320

Query: 361 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 420
           SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT
Sbjct: 321 SPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPT 380

Query: 421 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 480
           DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY
Sbjct: 381 DGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSY 440

Query: 481 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 524
           CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL
Sbjct: 441 CEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKKL 484


>gi|4757950 cell division cycle 25B isoform 2 [Homo sapiens]
          Length = 566

 Score =  407 bits (1046), Expect = e-113
 Identities = 239/526 (45%), Positives = 319/526 (60%), Gaps = 46/526 (8%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP---LEVKNNSNLQRMGSSESTDSGFCLDSPGPL 92
           A   SPVT LT TM  L GLGS        L  + + +     SSES+D+G C+DSP P+
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSRSRLTHLSLSRRASESSLSSESSESSDAGLCMDSPSPM 105

Query: 93  DSK-----------------ENLENPMRRIHSLPQKLLGCSPALKR-SHSDSLDH----- 129
           D                    N +  +RR  S+P +LLG SP L+  ++S + D      
Sbjct: 106 DPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRNITNSQAPDGRRKSE 165

Query: 130 -DIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHG-LQEGKDLFTQRQNSAPARMLSSN 187
                     E+KEN+ F FK P +P      H+       ++ F QR +SAP  M  S 
Sbjct: 166 AGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSP 225

Query: 188 ERDSSEPGNFIPLFTPQSPVTATLSD--EDDGFVDLLDGENLKNEEETPSCMASLWTAPL 245
           +R   E     PL   +  +T    D  EDDGFVD+L+ + LK+++  P  M SL +APL
Sbjct: 226 DR-KMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESD-LKDDDAVPPGMESLISAPL 283

Query: 246 VMRTTNLD-------NRC-KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGA 297
           V      +       ++C +LF SPS+  S  R +LKR ER Q+   P   KRR+S++  
Sbjct: 284 VKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVT-- 341

Query: 298 SPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDL 357
            P+E    E+    + +S SL       IEN+LD+D R+LIGD+SK +L  TV GKHQDL
Sbjct: 342 PPEEQQEAEEPKARVLRSKSLCHDE---IENLLDSDHRELIGDYSKAFLLQTVDGKHQDL 398

Query: 358 KYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPI 417
           KYISPE M ++L GKF+N++ +FVI+DCRYPYEYEGGHIK AVNL +E + E FLLK PI
Sbjct: 399 KYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPI 458

Query: 418 VPTD-GKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMK 476
            P    KRVI++FHCEFSSERGPRMCR++RERDR  N+YP L+YPE+Y+LKGGYKEFF +
Sbjct: 459 APCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQ 518

Query: 477 CQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLK 522
             ++CEP  YRPM+HE FK++LK FR K+R+WAGE+S+RE+ SRL+
Sbjct: 519 HPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQ 564


>gi|11641413 cell division cycle 25B isoform 1 [Homo sapiens]
          Length = 580

 Score =  406 bits (1044), Expect = e-113
 Identities = 241/540 (44%), Positives = 323/540 (59%), Gaps = 60/540 (11%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP----LEVKNNSNLQRMG-------------SSE 78
           A   SPVT LT TM  L GLGS+  +     L  ++ S L  +              SSE
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSE 105

Query: 79  STDSGFCLDSPGPLDSK-----------------ENLENPMRRIHSLPQKLLGCSPALKR 121
           S+D+G C+DSP P+D                    N +  +RR  S+P +LLG SP L+ 
Sbjct: 106 SSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSMPVRLLGHSPVLRN 165

Query: 122 -SHSDSLDH------DIFQLIDPDENKENEAFEFKKPVRPVSRGCLHSHG-LQEGKDLFT 173
            ++S + D                E+KEN+ F FK P +P      H+       ++ F 
Sbjct: 166 ITNSQAPDGRRKSEAGSGAASSSGEDKENDGFVFKMPWKPTHPSSTHALAEWASRREAFA 225

Query: 174 QRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSD--EDDGFVDLLDGENLKNEE 231
           QR +SAP  M  S +R   E     PL   +  +T    D  EDDGFVD+L+ + LK+++
Sbjct: 226 QRPSSAPDLMCLSPDR-KMEVEELSPLALGRFSLTPAEGDTEEDDGFVDILESD-LKDDD 283

Query: 232 ETPSCMASLWTAPLVMRTTNLD-------NRC-KLFDSPSLCSSSTRSVLKRPERSQEES 283
             P  M SL +APLV      +       ++C +LF SPS+  S  R +LKR ER Q+  
Sbjct: 284 AVPPGMESLISAPLVKTLEKEEEKDLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRD 343

Query: 284 PPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSK 343
            P   KRR+S++   P+E    E+    + +S SL       IEN+LD+D R+LIGD+SK
Sbjct: 344 TPVQNKRRRSVT--PPEEQQEAEEPKARVLRSKSLCHDE---IENLLDSDHRELIGDYSK 398

Query: 344 GYLFHTVAGKHQDLKYISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLH 403
            +L  TV GKHQDLKYISPE M ++L GKF+N++ +FVI+DCRYPYEYEGGHIK AVNL 
Sbjct: 399 AFLLQTVDGKHQDLKYISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLP 458

Query: 404 MEEEVEDFLLKKPIVPTD-GKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPE 462
           +E + E FLLK PI P    KRVI++FHCEFSSERGPRMCR++RERDR  N+YP L+YPE
Sbjct: 459 LERDAESFLLKSPIAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPE 518

Query: 463 LYVLKGGYKEFFMKCQSYCEPPSYRPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLK 522
           +Y+LKGGYKEFF +  ++CEP  YRPM+HE FK++LK FR K+R+WAGE+S+RE+ SRL+
Sbjct: 519 MYILKGGYKEFFPQHPNFCEPQDYRPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQ 578


>gi|11641411 cell division cycle 25B isoform 3 [Homo sapiens]
          Length = 539

 Score =  388 bits (996), Expect = e-108
 Identities = 230/516 (44%), Positives = 309/516 (59%), Gaps = 53/516 (10%)

Query: 36  AGGLSPVTNLTVTMDQLQGLGSDYEQP----LEVKNNSNLQRMG-------------SSE 78
           A   SPVT LT TM  L GLGS+  +     L  ++ S L  +              SSE
Sbjct: 46  AAASSPVTTLTQTMHDLAGLGSETPKSQVGTLLFRSRSRLTHLSLSRRASESSLSSESSE 105

Query: 79  STDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPD 138
           S+D+G C+DSP P+D     +   + I +  + +     A++R  S            PD
Sbjct: 106 SSDAGLCMDSPSPMDPHMAEQTFEQAIQAASRIIRNEQFAIRRFQSM-----------PD 154

Query: 139 ENKENEAFEFKKPVRPVSRGCLHSHG-LQEGKDLFTQRQNSAPARMLSSNERDSSEPGNF 197
                  F FK P +P      H+       ++ F QR +SAP  M  S +R   E    
Sbjct: 155 ------GFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDR-KMEVEEL 207

Query: 198 IPLFTPQSPVTATLSD--EDDGFVDLLDGENLKNEEETPSCMASLWTAPLVMRTTNLD-- 253
            PL   +  +T    D  EDDGFVD+L+ + LK+++  P  M SL +APLV      +  
Sbjct: 208 SPLALGRFSLTPAEGDTEEDDGFVDILESD-LKDDDAVPPGMESLISAPLVKTLEKEEEK 266

Query: 254 -----NRC-KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEK 307
                ++C +LF SPS+  S  R +LKR ER Q+   P   KRR+S++   P+E    E+
Sbjct: 267 DLVMYSKCQRLFRSPSMPCSVIRPILKRLERPQDRDTPVQNKRRRSVT--PPEEQQEAEE 324

Query: 308 AHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLKYISPEIMAS 367
               + +S SL       IEN+LD+D R+LIGD+SK +L  TV GKHQDLKYISPE M +
Sbjct: 325 PKARVLRSKSLCHDE---IENLLDSDHRELIGDYSKAFLLQTVDGKHQDLKYISPETMVA 381

Query: 368 VLNGKFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTD-GKRVI 426
           +L GKF+N++ +FVI+DCRYPYEYEGGHIK AVNL +E + E FLLK PI P    KRVI
Sbjct: 382 LLTGKFSNIVDKFVIVDCRYPYEYEGGHIKTAVNLPLERDAESFLLKSPIAPCSLDKRVI 441

Query: 427 VVFHCEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSY 486
           ++FHCEFSSERGPRMCR++RERDR  N+YP L+YPE+Y+LKGGYKEFF +  ++CEP  Y
Sbjct: 442 LIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYYPEMYILKGGYKEFFPQHPNFCEPQDY 501

Query: 487 RPMHHEDFKEDLKKFRTKSRTWAGEKSKREMYSRLK 522
           RPM+HE FK++LK FR K+R+WAGE+S+RE+ SRL+
Sbjct: 502 RPMNHEAFKDELKTFRLKTRSWAGERSRRELCSRLQ 537


>gi|125625350 cell division cycle 25C isoform a [Homo sapiens]
          Length = 473

 Score =  255 bits (652), Expect = 6e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 254 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 313
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 207 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 259

Query: 314 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 371
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 260 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 316

Query: 372 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 430
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 317 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 376

Query: 431 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 490
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 377 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 436

Query: 491 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 523
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 437 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 469


>gi|12408658 cell division cycle 25C isoform b [Homo sapiens]
          Length = 400

 Score =  255 bits (652), Expect = 6e-68
 Identities = 132/273 (48%), Positives = 183/273 (67%), Gaps = 13/273 (4%)

Query: 254 NRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLH 313
           +R  L+ SPS+  +  R  LK+ E+ ++ + P   K++        ++          L 
Sbjct: 134 SRSGLYRSPSMPENLNRPRLKQVEKFKDNTIPDKVKKKYFSGQGKLRKGL-------CLK 186

Query: 314 QSLSLASSPKGTIENILDNDPRD--LIGDFSKGYLFHTVAGKHQDLKYISPEIMASVLNG 371
           +++SL      TI  +L+ D     LIGDFSK     TV+GKHQDLKY++PE +A++L+G
Sbjct: 187 KTVSLCDI---TITQMLEEDSNQGHLIGDFSKVCALPTVSGKHQDLKYVNPETVAALLSG 243

Query: 372 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDG-KRVIVVFH 430
           KF  LI++F +IDCRYPYEY GGHI+GA+NL+ +EE+ +F LKKPIVP D  KR+I+VFH
Sbjct: 244 KFQGLIEKFYVIDCRYPYEYLGGHIQGALNLYSQEELFNFFLKKPIVPLDTQKRIIIVFH 303

Query: 431 CEFSSERGPRMCRYVRERDRLGNEYPKLHYPELYVLKGGYKEFFMKCQSYCEPPSYRPMH 490
           CEFSSERGPRMCR +RE DR  N+YP L+YPELY+LKGGY++FF +    CEP SY PMH
Sbjct: 304 CEFSSERGPRMCRCLREEDRSLNQYPALYYPELYILKGGYRDFFPEYMELCEPQSYCPMH 363

Query: 491 HEDFKEDLKKFRTKSRTWAGEKSKREMYSRLKK 523
           H+D K +L + R++S+   GE+  RE  + L K
Sbjct: 364 HQDHKTELLRCRSQSKVQEGERQLREQIALLVK 396


>gi|221219050 transducin-like enhancer protein 2 isoform 3 [Homo
           sapiens]
          Length = 621

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 16/202 (7%)

Query: 179 APARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMA 238
           +P   L   ER S   G        + P     SDED    +L+  E+  +E  +P+   
Sbjct: 73  SPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA--- 129

Query: 239 SLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGAS 298
              T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + 
Sbjct: 130 ---TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSP 186

Query: 299 PKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 358
           P++++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL 
Sbjct: 187 PQDASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLS 244

Query: 359 --------YISPEIMASVLNGK 372
                   ++SP++ +SV+ G+
Sbjct: 245 VPSSYVSLHLSPQVSSSVVYGR 266


>gi|221219048 transducin-like enhancer protein 2 isoform 2 [Homo
           sapiens]
          Length = 706

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 16/202 (7%)

Query: 179 APARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMA 238
           +P   L   ER S   G        + P     SDED    +L+  E+  +E  +P+   
Sbjct: 209 SPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA--- 265

Query: 239 SLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGAS 298
              T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + 
Sbjct: 266 ---TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSP 322

Query: 299 PKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 358
           P++++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL 
Sbjct: 323 PQDASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLS 380

Query: 359 --------YISPEIMASVLNGK 372
                   ++SP++ +SV+ G+
Sbjct: 381 VPSSYVSLHLSPQVSSSVVYGR 402


>gi|21361151 transducin-like enhancer protein 2 isoform 1 [Homo
           sapiens]
          Length = 743

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 47/202 (23%), Positives = 82/202 (40%), Gaps = 16/202 (7%)

Query: 179 APARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETPSCMA 238
           +P   L   ER S   G        + P     SDED    +L+  E+  +E  +P+   
Sbjct: 195 SPPESLVEEERPSGPGGGGKQRADEKEPSGPYESDEDKSDYNLVVDEDQPSEPPSPA--- 251

Query: 239 SLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGAS 298
              T P       +  R  L DSP+  +SS  S L R +       P ST   KS   + 
Sbjct: 252 ---TTPCGKVPICIPARRDLVDSPASLASSLGSPLPRAKELILNDLPASTPASKSCDSSP 308

Query: 299 PKESTNPEKAHETLHQSLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 358
           P++++ P     +      LA+ P  + +++    P  L   F+  +   + +  + DL 
Sbjct: 309 PQDASTP--GPSSASHLCQLAAKPAPSTDSVALRSPLTLSSPFTTSFSLGSHSTLNGDLS 366

Query: 359 --------YISPEIMASVLNGK 372
                   ++SP++ +SV+ G+
Sbjct: 367 VPSSYVSLHLSPQVSSSVVYGR 388


>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
          Length = 238

 Score = 37.0 bits (84), Expect = 0.044
 Identities = 22/51 (43%), Positives = 31/51 (60%), Gaps = 2/51 (3%)

Query: 257 KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEK 307
           + F SPS   S +RS+  RP  S+ +S   S KR +S SG SP+ S +PE+
Sbjct: 188 RYFQSPSRSRSRSRSI-SRPRSSRSKSRSPSPKRSRSPSG-SPRRSASPER 236


>gi|40538736 RAN binding protein 10 [Homo sapiens]
          Length = 620

 Score = 36.2 bits (82), Expect = 0.075
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 8/104 (7%)

Query: 260 DSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASP-----KESTNPEKAHETLHQ 314
           DSPS CS+   S   +   S+  +P  S+    S S +SP      ES + +      H 
Sbjct: 385 DSPS-CSNGVASTKSKQNHSKYPAPSSSSSSSSSSSSSSPSSVNYSESNSTDSTKSQHHS 443

Query: 315 SLSLASSPKGTIENILDNDPRDLIGDFSKGYLFHTVAGKHQDLK 358
           S S   +    +E   ++ P  ++G  S   +    A KH+DL+
Sbjct: 444 STSNQETSDSEMEMEAEHYPNGVLGSMSTRIV--NGAYKHEDLQ 485


>gi|197245440 hypothetical protein LOC23285 [Homo sapiens]
          Length = 1354

 Score = 34.7 bits (78), Expect = 0.22
 Identities = 56/265 (21%), Positives = 99/265 (37%), Gaps = 52/265 (19%)

Query: 84  FCLDSPGPL--DSKENLENPMRRIHSLPQKLLGCSPALKRSHSDSLDHDIFQLIDPDENK 141
           FC DSPG +  +S ++++N    I S P   +    + K+S           + + D N 
Sbjct: 326 FC-DSPGQMMKNSVDSVKNSTVAIKSRPVSRVTNGTSNKKS-----------IHEQDTNV 373

Query: 142 ENEAFEF---KKPVRPVSRGCLHSHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFI 198
            N   +    K    PV +  L   G   G     QR  S P+ +  +       P +  
Sbjct: 374 NNSVLKKVSGKGCSEPVPQAILKKRGTSNGCTAAQQRTKSTPSNLTKTQGSQGESPNSV- 432

Query: 199 PLFTPQSPVTATLSDEDDGFVDLLDGENLKNEEETP--SCMASLWTA-PLVMRTTNLDNR 255
                +S V++  SDE+   +D     N   E++ P    +  + TA P V         
Sbjct: 433 -----KSSVSSRQSDENVAKLD----HNTTTEKQAPKRKMVKQVHTALPKV--------N 475

Query: 256 CKLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQS 315
            K+   P   + S +      + S+++ PPG    +   S   P +       HET    
Sbjct: 476 AKIVAMPKNLNQSKKGETLNNKDSKQKMPPGQVISKTQPSSQRPLK-------HET---- 524

Query: 316 LSLASSPKGTIENILDNDPRDLIGD 340
              ++  K    ++ DN+ +D + +
Sbjct: 525 ---STVQKSMFHDVRDNNNKDSVSE 546


>gi|162287219 prune homolog 2 [Homo sapiens]
          Length = 3088

 Score = 33.5 bits (75), Expect = 0.49
 Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 12/112 (10%)

Query: 173  TQRQNSAPARML--SSNERDSSEPGNFIPLFTPQSPVTATLS-----DEDDGFVDLLDGE 225
            T  +   P + L  SS  R SS PGN     +P +  ++ ++     DE++   +  DG+
Sbjct: 1004 TAEETDIPPQSLQQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGK 1063

Query: 226  NLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPE 277
            N+  E++      S +  P +M+  N  NR       +L  SST S    P+
Sbjct: 1064 NISMEDDVGESSQSSYDDPSMMQLYNETNR-----QLTLLHSSTNSRQTAPD 1110



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 43/207 (20%), Positives = 75/207 (36%), Gaps = 21/207 (10%)

Query: 117 PALKRSHSDSLDHDIFQLIDPDEN--------KENEAFEFKKPVRPVSRGCLHSHGLQEG 168
           P L  S+   +D ++  L+ PD             E+  F     PV  G    H L  G
Sbjct: 407 PDLNDSNQAQVDANV-DLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPG 465

Query: 169 KDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFT-PQSPVTATLSDEDDGFVDLLDGENL 227
            D ++      P   ++     S E G    LF    +P+ +  S +     D    ++ 
Sbjct: 466 LDSYSP----IPEGAVAEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDF 521

Query: 228 KNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERS---QEESP 284
               +            L    TN+ N    + S SL S + +  L   +     +++SP
Sbjct: 522 FPNSDLSEGQLPAGPEGLDGMGTNMSN----YSSSSLLSGAGKDSLVEHDEEFVQRQDSP 577

Query: 285 PGSTKRRKSMSGASPKESTNPEKAHET 311
             +++R  S++     ES +PE+   T
Sbjct: 578 RDNSERNLSLTDFVGDESPSPERLKNT 604


>gi|169179759 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 17/42 (40%), Positives = 22/42 (52%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q    A+ G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSAVGGPMAAGEKPPVSRL 256


>gi|21361348 UTP14, U3 small nucleolar ribonucleoprotein, homolog A
           [Homo sapiens]
          Length = 771

 Score = 32.3 bits (72), Expect = 1.1
 Identities = 21/65 (32%), Positives = 31/65 (47%)

Query: 270 RSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLASSPKGTIENI 329
           RS+ KR E SQ+  P GS + + S S     E     +  +  HQS    +S +GTI  +
Sbjct: 428 RSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQV 487

Query: 330 LDNDP 334
              +P
Sbjct: 488 QREEP 492


>gi|169180158 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 32.0 bits (71), Expect = 1.4
 Identities = 17/42 (40%), Positives = 22/42 (52%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q    A+ G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSAVGGPVAAGEKPPVSRL 256


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 31.6 bits (70), Expect = 1.9
 Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 11/138 (7%)

Query: 168 GKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQ--SPVTATLSDEDDGFVDLLDGE 225
           GK L  + Q S  A   + + R SS      P  T    +P   T   +D  F       
Sbjct: 197 GKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCSQDTSFSS----- 251

Query: 226 NLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQEESPP 285
              + ++TPS     +T      T         +   S  SSST S   +P RS+     
Sbjct: 252 ---SRQDTPSSFGQ-FTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQD 307

Query: 286 GSTKRRKSMSGASPKEST 303
             ++R  S S AS   ST
Sbjct: 308 AFSRRHFSASSASTTAST 325


>gi|6005812 dual specificity phosphatase 10 isoform a [Homo sapiens]
          Length = 482

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 13/28 (46%), Positives = 20/28 (71%)

Query: 381 VIIDCRYPYEYEGGHIKGAVNLHMEEEV 408
           VIIDCR   EY   HI+GAV+++  +++
Sbjct: 173 VIIDCRPFMEYNKSHIQGAVHINCADKI 200


>gi|22748641 CHMP family, member 7 [Homo sapiens]
          Length = 453

 Score = 31.2 bits (69), Expect = 2.4
 Identities = 22/75 (29%), Positives = 32/75 (42%), Gaps = 7/75 (9%)

Query: 257 KLFDSPSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSL 316
           +L  S  L S    S+ +  ER +EE+       +K ++  S K     EK  E LH  L
Sbjct: 243 QLMQSEQLLSRKVESLSQEAERCKEEARRACRAGKKQLALRSLKAKQRTEKRIEALHAKL 302

Query: 317 SLASSPKGTIENILD 331
                   T++ ILD
Sbjct: 303 D-------TVQGILD 310


>gi|169183882 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 16/42 (38%), Positives = 21/42 (50%)

Query: 4   GPEPPHRRRLLFACSPPPASQPVVKALFGASAAGGLSPVTNL 45
           GP    R ++L AC+P P  Q     + G  AAG   PV+ L
Sbjct: 215 GPPGQEREQVLRACAPQPQHQVDCSTVGGPMAAGEKPPVSRL 256


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 30.8 bits (68), Expect = 3.2
 Identities = 35/157 (22%), Positives = 63/157 (40%), Gaps = 12/157 (7%)

Query: 162 SHGLQEGKDLFTQRQNSAPARMLS-SNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD 220
           S G  EG   +  R    P +  + ++++++SE G+      P SP  +  S   D    
Sbjct: 538 STGSHEGSSEWGGRPQGCPGKARAETSQQEASEGGD------PASPALSLSSLRSDDLQA 591

Query: 221 LLDGENLKNEEETPSCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLKRPERSQ 280
              G+    E+ T    A++   PLV+  +   +      +PS C+SS +   +   R+ 
Sbjct: 592 ETQGQG--TEQATG---AAVTREPLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRAS 646

Query: 281 EESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLS 317
             S P S    +      P+ S   +  H  L  S++
Sbjct: 647 AMSSPSSPGLGRVAPRGHPRHSHYRKDTHSPLDSSVT 683


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 34/161 (21%), Positives = 61/161 (37%), Gaps = 10/161 (6%)

Query: 63   LEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRS 122
            L  K N+   + GSS S       D+      K+   +  + +    +K      + KR 
Sbjct: 1102 LSSKRNTKEIQSGSSSSDAEESSEDNK---KKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1158

Query: 123  HSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCL---HSHGLQEGKDLFTQRQNSA 179
             +D        + D D+N   E    ++ ++PV+   +   H+   Q   D       S 
Sbjct: 1159 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGD--EALSKSV 1216

Query: 180  PARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD 220
            P  +   ++ D ++P N I        + A LS ++DG  D
Sbjct: 1217 PVTV--DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSD 1255


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 30.4 bits (67), Expect = 4.1
 Identities = 34/161 (21%), Positives = 61/161 (37%), Gaps = 10/161 (6%)

Query: 63   LEVKNNSNLQRMGSSESTDSGFCLDSPGPLDSKENLENPMRRIHSLPQKLLGCSPALKRS 122
            L  K N+   + GSS S       D+      K+   +  + +    +K      + KR 
Sbjct: 1140 LSSKRNTKEIQSGSSSSDAEESSEDNK---KKKQRTSSKKKAVIVKEKKRNSLRTSTKRK 1196

Query: 123  HSDSLDHDIFQLIDPDENKENEAFEFKKPVRPVSRGCL---HSHGLQEGKDLFTQRQNSA 179
             +D        + D D+N   E    ++ ++PV+   +   H+   Q   D       S 
Sbjct: 1197 QADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGD--EALSKSV 1254

Query: 180  PARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVD 220
            P  +   ++ D ++P N I        + A LS ++DG  D
Sbjct: 1255 PVTV--DDDDDDNDPENRIAKKMLLEEIKANLSSDEDGSSD 1293


>gi|148839466 kalirin, RhoGEF kinase isoform 1 [Homo sapiens]
          Length = 2986

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 165 LQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDL 221
           ++EG+DL  Q +++ P+    S  RDS+   N  P  +  S + + L   DD  V +
Sbjct: 698 IKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQM 754


>gi|4504335 kalirin, RhoGEF kinase isoform 2 [Homo sapiens]
          Length = 1663

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 17/57 (29%), Positives = 29/57 (50%)

Query: 165 LQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPLFTPQSPVTATLSDEDDGFVDL 221
           ++EG+DL  Q +++ P+    S  RDS+   N  P  +  S + + L   DD  V +
Sbjct: 698 IKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQM 754


>gi|8659574 transcription factor E3 [Homo sapiens]
          Length = 575

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 31/151 (20%), Positives = 59/151 (39%), Gaps = 12/151 (7%)

Query: 162 SHGLQEGKDLFTQRQNSAPARMLSSNERDSSEPGNFIPL--FTPQSPVTATLSDEDDGFV 219
           SH  +  +D          A  +   ER  ++    + L    P+S + A +  E+    
Sbjct: 2   SHAAEPARDGVEASAEGPRAVFVLLEERRPADSAQLLSLNSLLPESGIVADIELEN---- 57

Query: 220 DLLDGENLKNEEETP-----SCMASLWTAPLVMRTTNLDNRCKLFDSPSLCSSSTRSVLK 274
            +LD ++    +  P     S   SL   P    T +  +      +P++ SSS+  VL 
Sbjct: 58  -VLDPDSFYELKSQPLPLRSSLPISLQATPATPATLSASSSAGGSRTPAMSSSSSSRVLL 116

Query: 275 RPERSQEESPPGSTKRRKSMSGASPKESTNP 305
           R +  + ++     + R+  + A+P  S  P
Sbjct: 117 RQQLMRAQAQEQERRERREQAAAAPFPSPAP 147


>gi|21361458 Rho guanine nucleotide exchange factor (GEF) 17 [Homo
           sapiens]
          Length = 2063

 Score = 30.0 bits (66), Expect = 5.4
 Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 2/58 (3%)

Query: 262 PSLCSSSTRSVLKRPERSQEESPPGSTKRRKSMSGASPKESTNPEKAHETLHQSLSLA 319
           P L  SS+  +L       EE  PG+T+ R     A P+    P  AH   H    LA
Sbjct: 855 PMLPPSSSEPILVEQRAEPEE--PGATRSRAQSERALPEALPPPATAHRNFHLDPKLA 910


>gi|4580422 natriuretic peptide receptor B precursor [Homo sapiens]
          Length = 1047

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 30/118 (25%), Positives = 51/118 (43%), Gaps = 19/118 (16%)

Query: 322 PKGTIENILDNDP--------RDLIGDFSKG--YLFHTVAGKHQDLKYISPEIMASVLNG 371
           P+G++++IL+ND           LI D  KG  +L +++   H  LK  +      V++ 
Sbjct: 600 PRGSLQDILENDSINLDWMFRYSLINDLVKGMAFLHNSIISSHGSLKSSN-----CVVDS 654

Query: 372 KFANLIKEFVIIDCRYPYEYEGGHIKGAVNLHMEEEVEDFLLKKPIVPTDGKRVIVVF 429
           +F   I ++ +   R   E +  H   A  L    E    LL    +PT G +   V+
Sbjct: 655 RFVLKITDYGLASFRSTAEPDDSHALYAKKLWTAPE----LLSGNPLPTTGMQKADVY 708


>gi|116235478 establishment of cohesion 1 homolog 1 [Homo sapiens]
          Length = 840

 Score = 29.6 bits (65), Expect = 7.0
 Identities = 17/74 (22%), Positives = 33/74 (44%), Gaps = 3/74 (4%)

Query: 263 SLCSSSTRSVLKRPERSQEESPPGST---KRRKSMSGASPKESTNPEKAHETLHQSLSLA 319
           S C+  +    ++  R  E  P   T   KR K  +   PK++   +  H  ++ + +L 
Sbjct: 218 SQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATSVVPKKNEMKKSVHTQVNTNTTLP 277

Query: 320 SSPKGTIENILDND 333
            SP+ ++    DN+
Sbjct: 278 KSPQPSVPEQSDNE 291


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,689,395
Number of Sequences: 37866
Number of extensions: 1209590
Number of successful extensions: 3489
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 24
Number of HSP's that attempted gapping in prelim test: 3423
Number of HSP's gapped (non-prelim): 70
length of query: 524
length of database: 18,247,518
effective HSP length: 107
effective length of query: 417
effective length of database: 14,195,856
effective search space: 5919671952
effective search space used: 5919671952
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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