Guide to the Human Genome
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Search of human proteins with 42403575

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|42403575 four and a half LIM domains 2 [Homo sapiens]
         (279 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|87159836 four and a half LIM domains 2 [Homo sapiens]              632   0.0  
gi|87159834 four and a half LIM domains 2 [Homo sapiens]              632   0.0  
gi|42403575 four and a half LIM domains 2 [Homo sapiens]              632   0.0  
gi|87159832 four and a half LIM domains 2 [Homo sapiens]              632   0.0  
gi|30410801 activator of cAMP-responsive element modulator (CREM...   406   e-114
gi|54112385 four and a half LIM domains 3 [Homo sapiens]              379   e-105
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]   335   2e-92
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]   335   2e-92
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]   335   2e-92
gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]   335   2e-92
gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]    335   2e-92
gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]   286   2e-77
gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]   193   1e-49
gi|170932518 paxillin isoform 3 [Homo sapiens]                        137   1e-32
gi|170932516 paxillin isoform 2 [Homo sapiens]                        137   1e-32
gi|170932514 paxillin isoform 1 [Homo sapiens]                        137   1e-32
gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo ...   120   2e-27
gi|238859658 LIM and senescent cell antigen-like domains 2 isofo...   117   1e-26
gi|238776788 LIM and senescent cell antigen-like domains 2 isofo...   117   1e-26
gi|238776786 LIM and senescent cell antigen-like domains 2 isofo...   117   1e-26
gi|40804748 LIM and senescent cell antigen-like domains 2 isofor...   117   1e-26
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            112   4e-25
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             112   4e-25
gi|221316659 leupaxin isoform 1 [Homo sapiens]                        112   5e-25
gi|4758670 leupaxin isoform 2 [Homo sapiens]                          112   5e-25
gi|109638745 transforming growth factor beta 1 induced transcrip...   112   5e-25
gi|21361591 transforming growth factor beta 1 induced transcript...   112   5e-25
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]             109   3e-24
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]             109   3e-24
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            105   4e-23

>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  632 bits (1631), Expect = 0.0
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
           SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279


>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  632 bits (1631), Expect = 0.0
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
           SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279


>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  632 bits (1631), Expect = 0.0
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
           SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279


>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
          Length = 279

 Score =  632 bits (1631), Expect = 0.0
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH
Sbjct: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS
Sbjct: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
           SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP
Sbjct: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE
Sbjct: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI
Sbjct: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279


>gi|30410801 activator of cAMP-responsive element modulator (CREM)
           in testis [Homo sapiens]
          Length = 284

 Score =  406 bits (1044), Expect = e-114
 Identities = 165/275 (60%), Positives = 217/275 (78%)

Query: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
           T  F C +C  SL GKKY+L+++SPYCV C++ +F+N CEEC KPI  D KDL YKDRHW
Sbjct: 3   TAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHW 62

Query: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSS 121
           HE CF C++C +SLV+KPFAAK+++LLCT+CYSNE SSKC  CK+TIMPG+RKME+KG+ 
Sbjct: 63  HEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNY 122

Query: 122 WHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPW 181
           WHETCF+C  C+QPIGTK  I K++ N+CVPC+EK+ A  C  CKK IT+GG+T+ +Q W
Sbjct: 123 WHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLW 182

Query: 182 HKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEE 241
           HKECF+C+ CRK L  ++F +RDD+ +C++C+  LYA KC  C+ PISGL G K+I F++
Sbjct: 183 HKECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQD 242

Query: 242 RQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCG 276
            QWH++CFNC KCS+SLVG+GFLT+  +I C  CG
Sbjct: 243 SQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCG 277



 Score = 78.2 bits (191), Expect = 7e-15
 Identities = 33/94 (35%), Positives = 52/94 (55%), Gaps = 2/94 (2%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIG--CDCKDLSYKDRH 60
           E F C  C + L  ++++ R++ P+C+ C+  L+AN C  C KPI      K + ++D  
Sbjct: 185 ECFLCSGCRKDLCEEQFMSRDDYPFCMDCYNHLYANKCVACSKPISGLTGAKFICFQDSQ 244

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
           WH  CF+C +C  SLV K F  +  ++ C  C S
Sbjct: 245 WHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGS 278


>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
          Length = 280

 Score =  379 bits (974), Expect = e-105
 Identities = 149/277 (53%), Positives = 208/277 (75%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M+E FDC  CNESL+G+KYI  +  PYCV C++  FANTC EC + IG D ++L Y+DRH
Sbjct: 1   MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRH 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           +HE CF C +C+ SL D+PF  ++ +LLC DCY + +SS+C  C +T+MPG+RK+EY G 
Sbjct: 61  FHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQ 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
           +WHE CF+C  C+QP+G++SF+P    ++CVPCYE + A +C +C K +T GGVTYR+QP
Sbjct: 121 TWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           WH+EC VCT C+  L+GQ+FT+RD+  YC+ CF +L+A KC+ C  PI GLGG KY+SFE
Sbjct: 181 WHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFE 240

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
           +R WH++CF+C +CS SLVG+GF+ + D +LC  C +
Sbjct: 241 DRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQ 277


>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  335 bits (860), Expect = 2e-92
 Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G G G+  +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           E + WH+ CF+CKKCS++L  + F+  ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  335 bits (860), Expect = 2e-92
 Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G G G+  +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           E + WH+ CF+CKKCS++L  + F+  ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
          Length = 309

 Score =  335 bits (860), Expect = 2e-92
 Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 30  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 89

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 90  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 149

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 150 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 209

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G G G+  +++
Sbjct: 210 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 269

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           E + WH+ CF+CKKCS++L  + F+  ++ + CPDC K +
Sbjct: 270 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 309


>gi|228480205 four and a half LIM domains 1 isoform 5 [Homo sapiens]
          Length = 296

 Score =  335 bits (860), Expect = 2e-92
 Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 17  MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 76

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 77  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 136

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 137 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 196

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G G G+  +++
Sbjct: 197 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 256

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           E + WH+ CF+CKKCS++L  + F+  ++ + CPDC K +
Sbjct: 257 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 296


>gi|21361122 four and a half LIM domains 1 isoform 2 [Homo sapiens]
          Length = 280

 Score =  335 bits (860), Expect = 2e-92
 Identities = 135/280 (48%), Positives = 196/280 (70%), Gaps = 1/280 (0%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLG-GTKYISF 239
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G G G+  +++
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVVAY 240

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI 279
           E + WH+ CF+CKKCS++L  + F+  ++ + CPDC K +
Sbjct: 241 EGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDCAKKL 280


>gi|228480211 four and a half LIM domains 1 isoform 1 [Homo sapiens]
          Length = 323

 Score =  286 bits (731), Expect = 2e-77
 Identities = 116/230 (50%), Positives = 162/230 (70%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQP 180
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K IT+GG+TY++QP
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQDQP 180

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISG 230
           WH +CFVC  C K+L+GQRFTA +D  YC++C+ +  AKKCAGC NPI+G
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITG 230



 Score =  162 bits (409), Expect = 4e-40
 Identities = 71/215 (33%), Positives = 111/215 (51%), Gaps = 6/215 (2%)

Query: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C   I+  G    I+++++ 
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG----ITYQDQP 180

Query: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
           WH DCF C  CS  L G+ F    D   C DC K+
Sbjct: 181 WHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKN 215


>gi|228480221 four and a half LIM domains 1 isoform 4 [Homo sapiens]
          Length = 194

 Score =  193 bits (491), Expect = 1e-49
 Identities = 79/174 (45%), Positives = 113/174 (64%)

Query: 1   MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRH 60
           M E+FDCH+C + L GKKY+ ++    C+ CF+   ANTC EC KPIG D K++ YK+R 
Sbjct: 1   MAEKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRF 60

Query: 61  WHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
           WH+ CF C++C + L ++ F AK++++LC  C + E S KC+ C K I+ G + +EYKG+
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGT 120

Query: 121 SWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGV 174
            WH+ CF C  C+Q IGT SF PK    +CV C+E + A  CV+C K +    V
Sbjct: 121 VWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKGLVKAPV 174



 Score =  125 bits (313), Expect = 5e-29
 Identities = 52/161 (32%), Positives = 84/161 (52%), Gaps = 2/161 (1%)

Query: 66  FHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHET 125
           F C  CR+ L  K +  K+    C  C+    ++ C EC+K I   ++++ YK   WH+T
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 126 CFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTG--GVTYREQPWHK 183
           CF C +C  P+  ++F+ KDN+  C  C  ++ + +C  C K I  G   V Y+   WHK
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVWHK 124

Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGC 224
           +CF C+ C++ +    F  + +  YC+ C    +AK C  C
Sbjct: 125 DCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKC 165



 Score =  110 bits (274), Expect = 2e-24
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 4/151 (2%)

Query: 127 FICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTYREQPWHKE 184
           F CH C+ P+  K ++ KD  + C+ C++K  A  CV+C+KPI      V Y+ + WH  
Sbjct: 5   FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64

Query: 185 CFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQW 244
           CF C  C   L+ + F A+D+   C  C     + KC GC   I  + G + + ++   W
Sbjct: 65  CFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAI--VAGDQNVEYKGTVW 122

Query: 245 HNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
           H DCF C  C   +    F  + +D  C  C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYCVTC 153



 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 32/92 (34%), Positives = 44/92 (47%), Gaps = 2/92 (2%)

Query: 184 ECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQ 243
           E F C  CR  L G+++  +D    CL CF    A  C  C  PI     +K + ++ R 
Sbjct: 3   EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIG--ADSKEVHYKNRF 60

Query: 244 WHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
           WH+ CF C KC   L    F+ + + ILC  C
Sbjct: 61  WHDTCFRCAKCLHPLANETFVAKDNKILCNKC 92


>gi|170932518 paxillin isoform 3 [Homo sapiens]
          Length = 424

 Score =  137 bits (344), Expect = 1e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 213 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 270

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 271 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 328

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 329 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 388

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 389 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423



 Score =  112 bits (281), Expect = 3e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 191 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 248

Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 249 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 308

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 309 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 364

Query: 269 DILCPDCGKDI 279
             LC  C K I
Sbjct: 365 GSLCSGCQKPI 375



 Score =  106 bits (265), Expect = 2e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 185 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 242

Query: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 243 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 300

Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 301 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 360

Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 361 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416

Query: 274 DC 275
           +C
Sbjct: 417 NC 418


>gi|170932516 paxillin isoform 2 [Homo sapiens]
          Length = 557

 Score =  137 bits (344), Expect = 1e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 346 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 403

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 404 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 461

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 462 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 521

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 522 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556



 Score =  112 bits (281), Expect = 3e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 324 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 381

Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 382 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 441

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 442 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 497

Query: 269 DILCPDCGKDI 279
             LC  C K I
Sbjct: 498 GSLCSGCQKPI 508



 Score =  106 bits (265), Expect = 2e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 318 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 375

Query: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 376 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 433

Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 434 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 493

Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 494 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549

Query: 274 DC 275
           +C
Sbjct: 550 NC 551


>gi|170932514 paxillin isoform 1 [Homo sapiens]
          Length = 591

 Score =  137 bits (344), Expect = 1e-32
 Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C HC E +  + +  R+  PYC   +  LF+  C  C  PI  D K ++  DR WH
Sbjct: 380 EHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPI-LD-KVVTALDRTWH 437

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C+QC      + F  K+ +  C   Y + ++ KC  C + I+     +    + W
Sbjct: 438 PEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENY--ISALNTLW 495

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C  P    SF   D Q +C   Y ++    C  C+KPIT   +T   + +H
Sbjct: 496 HPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFH 555

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            E FVC  C KQL+   F  ++D  YC NCF  L+
Sbjct: 556 PEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590



 Score =  112 bits (281), Expect = 3e-25
 Identities = 61/191 (31%), Positives = 83/191 (43%), Gaps = 18/191 (9%)

Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
           C  CKK I    + +   G +WH   F+C  CQ+ IG+++F  +D Q +C   Y    + 
Sbjct: 358 CGACKKPI--AGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSP 415

Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
           +C  C  PI    VT  ++ WH E F C  C      + F  +D  AYC   + D++A K
Sbjct: 416 RCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPK 475

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLT------------ERD 268
           C GC   I       YIS     WH +CF C++C    V   F              ER 
Sbjct: 476 CGGCARAIL----ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERR 531

Query: 269 DILCPDCGKDI 279
             LC  C K I
Sbjct: 532 GSLCSGCQKPI 542



 Score =  106 bits (265), Expect = 2e-23
 Identities = 63/242 (26%), Positives = 99/242 (40%), Gaps = 8/242 (3%)

Query: 34  TLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCY 93
           T+    C  C KPI      ++   + WH   F C+ C+  +  + F  ++ Q  C   Y
Sbjct: 352 TVAKGVCGACKKPIAGQV--VTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDY 409

Query: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
            N +S +C  C   I+   + +     +WH   F C +C    G + F  KD + +C   
Sbjct: 410 HNLFSPRCYYCNGPILD--KVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKD 467

Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
           Y    A +C  C + I    ++     WH ECFVC  C        F   D   YC   +
Sbjct: 468 YFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHY 527

Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCP 273
            +     C+GC  PI+G    + I+   +++H + F C  C   L    F  + D   C 
Sbjct: 528 HERRGSLCSGCQKPITG----RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 583

Query: 274 DC 275
           +C
Sbjct: 584 NC 585


>gi|13518026 LIM and senescent cell antigen-like domains 1 [Homo
           sapiens]
          Length = 325

 Score =  120 bits (300), Expect = 2e-27
 Identities = 77/278 (27%), Positives = 113/278 (40%), Gaps = 16/278 (5%)

Query: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
           F C  C +      +   E   YC   F+ LFA  C +CG+ I    + +   +  WH  
Sbjct: 36  FVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFI--IGRVIKAMNNSWHPE 93

Query: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
           CF C  C+  L D  F     + LC  C++ E +       CQ+C   I    + + +K 
Sbjct: 94  CFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAII--DEQPLIFKN 151

Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
             +H   F C  C + + T        + +C+PC++K     C  C++PI    V    +
Sbjct: 152 DPYHPDHFNCANCGKEL-TADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGK 210

Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
            WH E FVC  C K   G R   R   AYC   +  L+   C  C   I G      +S 
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEG----DVVSA 266

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGK 277
             + W  +CF C  C+  L  +    E D  + P C K
Sbjct: 267 LNKAWCVNCFACSTCNTKLTLKNKFVEFD--MKPVCKK 302



 Score =  108 bits (269), Expect = 7e-24
 Identities = 60/231 (25%), Positives = 101/231 (43%), Gaps = 12/231 (5%)

Query: 35  LFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYS 94
           L + TCE C        K ++     +HE CF C+QC     +  F   E +  C   + 
Sbjct: 5   LASATCERCKGGFAPAEKIVNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQ 64

Query: 95  NEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCY 154
             ++  C +C + I+   R ++   +SWH  CF C  CQ+ +    F+    ++ C PC+
Sbjct: 65  MLFAPCCHQCGEFII--GRVIKAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCH 122

Query: 155 EKQHAMQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
            ++ A       C +C   I    + ++  P+H + F C  C K+L+      + +  YC
Sbjct: 123 NREKARGLGKYICQKCHAIIDEQPLIFKNDPYHPDHFNCANCGKELTADARELKGEL-YC 181

Query: 210 LNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
           L C   +    C  C  PI G    + ++   +QWH + F C KC    +G
Sbjct: 182 LPCHDKMGVPICGACRRPIEG----RVVNAMGKQWHVEHFVCAKCEKPFLG 228



 Score = 48.5 bits (114), Expect = 6e-06
 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 3/92 (3%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C +   G ++  R+   YC   +  LF + C  C + I  D   +S  ++ W 
Sbjct: 215 EHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV--VSALNKAWC 272

Query: 63  EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCY 93
             CF CS C   L  K  F   + + +C  CY
Sbjct: 273 VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCY 304


>gi|238859658 LIM and senescent cell antigen-like domains 2 isoform
           1 [Homo sapiens]
          Length = 363

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)

Query: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
           F C  C        +   E   YC   F+ LFA  C  CG+ I    + +   + +WH  
Sbjct: 63  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 120

Query: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
           CF C  C   L D  F     + LC  C++ E +       CQ C   I    + + ++ 
Sbjct: 121 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 178

Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
            ++H   F C  C + +  ++   K  + +C+PC++K     C  C++PI    V    +
Sbjct: 179 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 237

Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
            WH E FVC  C K   G R   +   AYC   +  L+   C  C++ I G      +S 
Sbjct: 238 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 293

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
             + W   CF+C  C+  L  +    E D
Sbjct: 294 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 322



 Score = 98.2 bits (243), Expect = 7e-21
 Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C+ C        + ++     +HE CF C+QC     +  F   E +  C   +   ++ 
Sbjct: 37  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 96

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C  C + I+   R ++   ++WH  CF C  C   +    F+    ++ C PC+ ++ A
Sbjct: 97  CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 154

Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
                  C +C   I    + +R   +H + F CT C K+L+ +    + +  YCL C  
Sbjct: 155 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 213

Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
            +    C  C  PI G    + ++   +QWH + F C KC    +G
Sbjct: 214 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 255



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           + F+C HC + L  +   L+ E  YC+ C + +    C  C +PI  + + ++   + WH
Sbjct: 184 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 240

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C++C    +      K+    C   Y+  +   C  C   I      +     +W
Sbjct: 241 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 298

Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
             +CF C  C   +  K+ F+  D +  C  CYEK
Sbjct: 299 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 333



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           +H+ CFVC  C +      F   +   YC + F  L+A  C  C   I G    + I   
Sbjct: 58  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 113

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
              WH  CF C+ C + L   GF+      LC  C
Sbjct: 114 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 148



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C +   G ++  ++   YC   +  LF + C  C   I  D   +S  ++ W 
Sbjct: 242 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 299

Query: 63  EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
            +CF CS C + L  K  F   + + +C  CY        +  KK     +RK + K +
Sbjct: 300 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 358


>gi|238776788 LIM and senescent cell antigen-like domains 2 isoform
           5 [Homo sapiens]
          Length = 336

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)

Query: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
           F C  C        +   E   YC   F+ LFA  C  CG+ I    + +   + +WH  
Sbjct: 36  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 93

Query: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
           CF C  C   L D  F     + LC  C++ E +       CQ C   I    + + ++ 
Sbjct: 94  CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 151

Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
            ++H   F C  C + +  ++   K  + +C+PC++K     C  C++PI    V    +
Sbjct: 152 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 210

Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
            WH E FVC  C K   G R   +   AYC   +  L+   C  C++ I G      +S 
Sbjct: 211 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 266

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
             + W   CF+C  C+  L  +    E D
Sbjct: 267 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 295



 Score = 98.2 bits (243), Expect = 7e-21
 Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C+ C        + ++     +HE CF C+QC     +  F   E +  C   +   ++ 
Sbjct: 10  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 69

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C  C + I+   R ++   ++WH  CF C  C   +    F+    ++ C PC+ ++ A
Sbjct: 70  CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 127

Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
                  C +C   I    + +R   +H + F CT C K+L+ +    + +  YCL C  
Sbjct: 128 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 186

Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
            +    C  C  PI G    + ++   +QWH + F C KC    +G
Sbjct: 187 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 228



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           + F+C HC + L  +   L+ E  YC+ C + +    C  C +PI  + + ++   + WH
Sbjct: 157 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 213

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C++C    +      K+    C   Y+  +   C  C   I      +     +W
Sbjct: 214 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 271

Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
             +CF C  C   +  K+ F+  D +  C  CYEK
Sbjct: 272 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 306



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           +H+ CFVC  C +      F   +   YC + F  L+A  C  C   I G    + I   
Sbjct: 31  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 86

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
              WH  CF C+ C + L   GF+      LC  C
Sbjct: 87  NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 121



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C +   G ++  ++   YC   +  LF + C  C   I  D   +S  ++ W 
Sbjct: 215 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 272

Query: 63  EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
            +CF CS C + L  K  F   + + +C  CY        +  KK     +RK + K +
Sbjct: 273 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 331


>gi|238776786 LIM and senescent cell antigen-like domains 2 isoform
           3 [Homo sapiens]
          Length = 341

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)

Query: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
           F C  C        +   E   YC   F+ LFA  C  CG+ I    + +   + +WH  
Sbjct: 41  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 98

Query: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
           CF C  C   L D  F     + LC  C++ E +       CQ C   I    + + ++ 
Sbjct: 99  CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 156

Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
            ++H   F C  C + +  ++   K  + +C+PC++K     C  C++PI    V    +
Sbjct: 157 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 215

Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
            WH E FVC  C K   G R   +   AYC   +  L+   C  C++ I G      +S 
Sbjct: 216 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 271

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
             + W   CF+C  C+  L  +    E D
Sbjct: 272 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 300



 Score = 98.2 bits (243), Expect = 7e-21
 Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C+ C        + ++     +HE CF C+QC     +  F   E +  C   +   ++ 
Sbjct: 15  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 74

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C  C + I+   R ++   ++WH  CF C  C   +    F+    ++ C PC+ ++ A
Sbjct: 75  CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 132

Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
                  C +C   I    + +R   +H + F CT C K+L+ +    + +  YCL C  
Sbjct: 133 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 191

Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
            +    C  C  PI G    + ++   +QWH + F C KC    +G
Sbjct: 192 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 233



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           + F+C HC + L  +   L+ E  YC+ C + +    C  C +PI  + + ++   + WH
Sbjct: 162 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 218

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C++C    +      K+    C   Y+  +   C  C   I      +     +W
Sbjct: 219 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 276

Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
             +CF C  C   +  K+ F+  D +  C  CYEK
Sbjct: 277 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 311



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           +H+ CFVC  C +      F   +   YC + F  L+A  C  C   I G    + I   
Sbjct: 36  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 91

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
              WH  CF C+ C + L   GF+      LC  C
Sbjct: 92  NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 126



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C +   G ++  ++   YC   +  LF + C  C   I  D   +S  ++ W 
Sbjct: 220 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 277

Query: 63  EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
            +CF CS C + L  K  F   + + +C  CY        +  KK     +RK + K +
Sbjct: 278 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 336


>gi|40804748 LIM and senescent cell antigen-like domains 2 isoform 2
           [Homo sapiens]
          Length = 365

 Score =  117 bits (293), Expect = 1e-26
 Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 14/269 (5%)

Query: 5   FDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEA 64
           F C  C        +   E   YC   F+ LFA  C  CG+ I    + +   + +WH  
Sbjct: 65  FVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFI--IGRVIKAMNNNWHPG 122

Query: 65  CFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSK-----CQECKKTIMPGTRKMEYKG 119
           CF C  C   L D  F     + LC  C++ E +       CQ C   I    + + ++ 
Sbjct: 123 CFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVI--DEQPLMFRS 180

Query: 120 SSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQ 179
            ++H   F C  C + +  ++   K  + +C+PC++K     C  C++PI    V    +
Sbjct: 181 DAYHPDHFNCTHCGKELTAEARELK-GELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 239

Query: 180 PWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISF 239
            WH E FVC  C K   G R   +   AYC   +  L+   C  C++ I G      +S 
Sbjct: 240 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEG----DVVSA 295

Query: 240 EERQWHNDCFNCKKCSLSLVGRGFLTERD 268
             + W   CF+C  C+  L  +    E D
Sbjct: 296 LNKAWCVSCFSCSTCNSKLTLKNKFVEFD 324



 Score = 98.2 bits (243), Expect = 7e-21
 Identities = 55/226 (24%), Positives = 96/226 (42%), Gaps = 12/226 (5%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C+ C        + ++     +HE CF C+QC     +  F   E +  C   +   ++ 
Sbjct: 39  CQRCQARFSPAERIVNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAP 98

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C  C + I+   R ++   ++WH  CF C  C   +    F+    ++ C PC+ ++ A
Sbjct: 99  CCGSCGEFII--GRVIKAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKA 156

Query: 160 MQ-----CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFC 214
                  C +C   I    + +R   +H + F CT C K+L+ +    + +  YCL C  
Sbjct: 157 KGLGKYICQRCHLVIDEQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGEL-YCLPCHD 215

Query: 215 DLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVG 260
            +    C  C  PI G    + ++   +QWH + F C KC    +G
Sbjct: 216 KMGVPICGACRRPIEG----RVVNALGKQWHVEHFVCAKCEKPFLG 257



 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 38/155 (24%), Positives = 65/155 (41%), Gaps = 6/155 (3%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           + F+C HC + L  +   L+ E  YC+ C + +    C  C +PI  + + ++   + WH
Sbjct: 186 DHFNCTHCGKELTAEARELKGEL-YCLPCHDKMGVPICGACRRPI--EGRVVNALGKQWH 242

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C++C    +      K+    C   Y+  +   C  C   I      +     +W
Sbjct: 243 VEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAW 300

Query: 123 HETCFICHRCQQPIGTKS-FIPKDNQNFCVPCYEK 156
             +CF C  C   +  K+ F+  D +  C  CYEK
Sbjct: 301 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEK 335



 Score = 55.8 bits (133), Expect = 4e-08
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 4/95 (4%)

Query: 181 WHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFE 240
           +H+ CFVC  C +      F   +   YC + F  L+A  C  C   I G    + I   
Sbjct: 60  YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIG----RVIKAM 115

Query: 241 ERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
              WH  CF C+ C + L   GF+      LC  C
Sbjct: 116 NNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPC 150



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 31/119 (26%), Positives = 50/119 (42%), Gaps = 3/119 (2%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C +   G ++  ++   YC   +  LF + C  C   I  D   +S  ++ W 
Sbjct: 244 EHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV--VSALNKAWC 301

Query: 63  EACFHCSQCRNSLVDK-PFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGS 120
            +CF CS C + L  K  F   + + +C  CY        +  KK     +RK + K +
Sbjct: 302 VSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 360


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  112 bits (280), Expect = 4e-25
 Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
           G SWH   F C  C+  +    F+ + N  +C  CYE+  A  C +C   I    +    
Sbjct: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516

Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
           Q WH  CFVC AC+K      F   D   YC   + +L++ KC GC  P+    G K+I 
Sbjct: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574

Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
                WH+ CF C  C ++L G+ F +++D  LC
Sbjct: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score =  103 bits (257), Expect = 2e-22
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)

Query: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
           R WH   F C+ C+ SL D  F  +++ + C  CY   ++  C +C   IM     M   
Sbjct: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
             +WH TCF+C  C++P G   F  +D + +C   Y    + +C  C  P+  G   +  
Sbjct: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575

Query: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
               WH  CF+C  C   L GQ F ++ D   C
Sbjct: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 92.0 bits (227), Expect = 5e-19
 Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C +C  SL    ++  + + YC  C+E  FA  C +C   I  +   +    + WH
Sbjct: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
             CF C+ C+    +  F  ++ +  C   Y N +S+KC  C   +  G + +E  G +W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           H+TCFIC  C   +  + F  K ++  C     K+HA
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612



 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 26/88 (29%), Positives = 41/88 (46%)

Query: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
           T  F C  C +      + + +  PYC   +  LF+  C  C  P+    K +      W
Sbjct: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580

Query: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
           H+ CF C+ C  +L  +PF +K+D+ LC
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
           C  C   I    +    + WH E F C  C+  L+   F    +  YC  C+   +A  C
Sbjct: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500

Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
           A C   I G    + +    + WH  CF C  C        F  E  +   P C KD
Sbjct: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  112 bits (280), Expect = 4e-25
 Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
           G SWH   F C  C+  +    F+ + N  +C  CYE+  A  C +C   I    +    
Sbjct: 567 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 626

Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
           Q WH  CFVC AC+K      F   D   YC   + +L++ KC GC  P+    G K+I 
Sbjct: 627 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 684

Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
                WH+ CF C  C ++L G+ F +++D  LC
Sbjct: 685 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score =  103 bits (257), Expect = 2e-22
 Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)

Query: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
           R WH   F C+ C+ SL D  F  +++ + C  CY   ++  C +C   IM     M   
Sbjct: 568 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 625

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
             +WH TCF+C  C++P G   F  +D + +C   Y    + +C  C  P+  G   +  
Sbjct: 626 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 685

Query: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
               WH  CF+C  C   L GQ F ++ D   C
Sbjct: 686 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 92.0 bits (227), Expect = 5e-19
 Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C +C  SL    ++  + + YC  C+E  FA  C +C   I  +   +    + WH
Sbjct: 573 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 630

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
             CF C+ C+    +  F  ++ +  C   Y N +S+KC  C   +  G + +E  G +W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           H+TCFIC  C   +  + F  K ++  C     K+HA
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 722



 Score = 58.2 bits (139), Expect = 8e-09
 Identities = 26/88 (29%), Positives = 41/88 (46%)

Query: 2   TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
           T  F C  C +      + + +  PYC   +  LF+  C  C  P+    K +      W
Sbjct: 631 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 690

Query: 62  HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
           H+ CF C+ C  +L  +PF +K+D+ LC
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLC 718



 Score = 55.1 bits (131), Expect = 7e-08
 Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
           C  C   I    +    + WH E F C  C+  L+   F    +  YC  C+   +A  C
Sbjct: 551 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 610

Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
           A C   I G    + +    + WH  CF C  C        F  E  +   P C KD
Sbjct: 611 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 660


>gi|221316659 leupaxin isoform 1 [Homo sapiens]
          Length = 391

 Score =  112 bits (279), Expect = 5e-25
 Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C HC E +    +  R    YC   +  LF+  C  C  PI  D K L+  ++ WH
Sbjct: 179 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI-LD-KVLTAMNQTWH 236

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F CS C      + F  K+ +  C   +   +S KC  C + ++     +    + W
Sbjct: 237 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDTVW 294

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C     T SF   D + FC   Y  +    C  C +PIT   ++     +H
Sbjct: 295 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 354

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            E FVC  C  QLS   F  ++D  YC  CF  L+
Sbjct: 355 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389



 Score =  105 bits (262), Expect = 4e-23
 Identities = 61/236 (25%), Positives = 94/236 (39%), Gaps = 8/236 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C  C KPI    K +    + WH   F C+ C+  +   PF  +     C + Y   +S 
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           +C  C   I+   + +     +WH   F C  C +  G + F  KD + +C   +    +
Sbjct: 215 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272

Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
            +C  C +P+    ++  +  WH ECFVC  C    S   F   D   +C   +      
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332

Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
            C GC  PI+G    + IS    ++H + F C  C   L    F  + D   C  C
Sbjct: 333 LCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 384



 Score =  103 bits (258), Expect = 1e-22
 Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 18/191 (9%)

Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
           C  C+K I    + +   G SWH   F+C  C++ IG+  F  +    +C   Y +  + 
Sbjct: 157 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 214

Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
           +C  C  PI    +T   Q WH E F C+ C +    + F  +D   YC   F  +++ K
Sbjct: 215 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 274

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLS--------LVGRGFLT----ERD 268
           C GC  P+       Y+S  +  WH +CF C  C  S        L GR F       R 
Sbjct: 275 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 330

Query: 269 DILCPDCGKDI 279
             LC  CG+ I
Sbjct: 331 GTLCHGCGQPI 341


>gi|4758670 leupaxin isoform 2 [Homo sapiens]
          Length = 386

 Score =  112 bits (279), Expect = 5e-25
 Identities = 65/215 (30%), Positives = 92/215 (42%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C HC E +    +  R    YC   +  LF+  C  C  PI  D K L+  ++ WH
Sbjct: 174 EHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRCAYCAAPI-LD-KVLTAMNQTWH 231

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F CS C      + F  K+ +  C   +   +S KC  C + ++     +    + W
Sbjct: 232 PEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCGGCNRPVLENY--LSAMDTVW 289

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C     T SF   D + FC   Y  +    C  C +PIT   ++     +H
Sbjct: 290 HPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGTLCHGCGQPITGRCISAMGYKFH 349

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            E FVC  C  QLS   F  ++D  YC  CF  L+
Sbjct: 350 PEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384



 Score =  105 bits (262), Expect = 4e-23
 Identities = 61/236 (25%), Positives = 94/236 (39%), Gaps = 8/236 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C  C KPI    K +    + WH   F C+ C+  +   PF  +     C + Y   +S 
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           +C  C   I+   + +     +WH   F C  C +  G + F  KD + +C   +    +
Sbjct: 210 RCAYCAAPIL--DKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267

Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
            +C  C +P+    ++  +  WH ECFVC  C    S   F   D   +C   +      
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327

Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
            C GC  PI+G    + IS    ++H + F C  C   L    F  + D   C  C
Sbjct: 328 LCHGCGQPITG----RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPC 379



 Score =  103 bits (258), Expect = 1e-22
 Identities = 57/191 (29%), Positives = 82/191 (42%), Gaps = 18/191 (9%)

Query: 101 CQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAM 160
           C  C+K I    + +   G SWH   F+C  C++ IG+  F  +    +C   Y +  + 
Sbjct: 152 CASCQKPI--AGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSP 209

Query: 161 QCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKK 220
           +C  C  PI    +T   Q WH E F C+ C +    + F  +D   YC   F  +++ K
Sbjct: 210 RCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPK 269

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLS--------LVGRGFLT----ERD 268
           C GC  P+       Y+S  +  WH +CF C  C  S        L GR F       R 
Sbjct: 270 CGGCNRPVL----ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRR 325

Query: 269 DILCPDCGKDI 279
             LC  CG+ I
Sbjct: 326 GTLCHGCGQPI 336


>gi|109638745 transforming growth factor beta 1 induced transcript 1
           isoform 1 [Homo sapiens]
          Length = 461

 Score =  112 bits (279), Expect = 5e-25
 Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C  C KPI      ++   R WH   F C  C  +L    F  K+    C +CY   +S 
Sbjct: 228 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 285

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           +C  C + I    + +   G+ WH   F C  C +P G + F  ++ + +C   + +  A
Sbjct: 286 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343

Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
            +C  C+ PI    ++     WH +CFVC  C    SG  F   +    C N F      
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403

Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
            CA C  P++G    + +S   R++H D F C  C   L    F        C  C
Sbjct: 404 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 455



 Score =  108 bits (269), Expect = 7e-24
 Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C+ +L G  +  ++ +P+C  C+   F+  C  C +PI    K ++    HWH
Sbjct: 250 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 307

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C  C     D+ F  +E +  C   +   ++ +CQ C+  I+     +    + W
Sbjct: 308 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 365

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C  P    SF   + +  C   +  +    C  C  P+T   V+   + +H
Sbjct: 366 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 425

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            + F CT C + L+   F  R    YC  CF  L+
Sbjct: 426 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460



 Score = 35.0 bits (79), Expect = 0.073
 Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)

Query: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
           +C +C K ++GQ  TA                          +D   +C  C+ + ++ +
Sbjct: 227 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 286

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
           C  C  PI      K ++     WH + F C  C       GF
Sbjct: 287 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 325


>gi|21361591 transforming growth factor beta 1 induced transcript 1
           isoform 2 [Homo sapiens]
          Length = 444

 Score =  112 bits (279), Expect = 5e-25
 Identities = 65/236 (27%), Positives = 96/236 (40%), Gaps = 8/236 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C  C KPI      ++   R WH   F C  C  +L    F  K+    C +CY   +S 
Sbjct: 211 CGSCNKPIAGQV--VTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSP 268

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           +C  C + I    + +   G+ WH   F C  C +P G + F  ++ + +C   + +  A
Sbjct: 269 RCGFCNQPIRH--KMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326

Query: 160 MQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAK 219
            +C  C+ PI    ++     WH +CFVC  C    SG  F   +    C N F      
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386

Query: 220 KCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
            CA C  P++G    + +S   R++H D F C  C   L    F        C  C
Sbjct: 387 LCATCGLPVTG----RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPC 438



 Score =  108 bits (269), Expect = 7e-24
 Identities = 57/215 (26%), Positives = 93/215 (43%), Gaps = 4/215 (1%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C+ +L G  +  ++ +P+C  C+   F+  C  C +PI    K ++    HWH
Sbjct: 233 EHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRH--KMVTALGTHWH 290

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
              F C  C     D+ F  +E +  C   +   ++ +CQ C+  I+     +    + W
Sbjct: 291 PEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPILDNY--ISALSALW 348

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWH 182
           H  CF+C  C  P    SF   + +  C   +  +    C  C  P+T   V+   + +H
Sbjct: 349 HPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGSLCATCGLPVTGRCVSALGRRFH 408

Query: 183 KECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLY 217
            + F CT C + L+   F  R    YC  CF  L+
Sbjct: 409 PDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443



 Score = 35.0 bits (79), Expect = 0.073
 Identities = 22/103 (21%), Positives = 36/103 (34%), Gaps = 30/103 (29%)

Query: 187 VCTACRKQLSGQRFTA--------------------------RDDFAYCLNCFCDLYAKK 220
           +C +C K ++GQ  TA                          +D   +C  C+ + ++ +
Sbjct: 210 LCGSCNKPIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPR 269

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGF 263
           C  C  PI      K ++     WH + F C  C       GF
Sbjct: 270 CGFCNQPIR----HKMVTALGTHWHPEHFCCVSCGEPFGDEGF 308


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score =  109 bits (272), Expect = 3e-24
 Identities = 52/179 (29%), Positives = 86/179 (48%), Gaps = 4/179 (2%)

Query: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
           +N  +  C +C K I    R +   G ++H   F+C +C + +    F  +    FC PC
Sbjct: 241 NNGKTPVCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298

Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
           Y+ ++A  C +CKK IT   +   +  WH  CF C AC+  +  + F   +   YC   +
Sbjct: 299 YDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 358

Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
             ++  KC GC   I    G +++      WH+ CF C  C ++L G+ F +++D  LC
Sbjct: 359 EKMFGTKCHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 6/172 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C +C K I    + L      +H   F CSQC   L +  F  ++  + C  CY   Y+ 
Sbjct: 248 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C +CKK I      M     +WH  CF C  C+ PI  ++F  ++   +C   YEK   
Sbjct: 306 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 363

Query: 160 MQCVQCKKPITTGG--VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
            +C  C   I  G   +      WH  CFVC  C+  L G+ F ++ D   C
Sbjct: 364 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 415



 Score = 88.6 bits (218), Expect = 6e-18
 Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C + L    +   + + +C  C++  +A +C +C K I  +   +      WH
Sbjct: 270 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 327

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
             CF C+ C+  + ++ F  +E    C   Y   + +KC  C   I  G R +E  G SW
Sbjct: 328 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 387

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCV 163
           H+TCF+C  CQ  +  K+F  K ++  C     K HA   V
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLC-----KSHAFSHV 423



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 4/55 (7%)

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
           C  C   I G    +Y+      +H + F C +C   L   GF  E+  I CP C
Sbjct: 248 CHQCHKVIRG----RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 298


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score =  109 bits (272), Expect = 3e-24
 Identities = 52/179 (29%), Positives = 86/179 (48%), Gaps = 4/179 (2%)

Query: 94  SNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPC 153
           +N  +  C +C K I    R +   G ++H   F+C +C + +    F  +    FC PC
Sbjct: 275 NNGKTPVCHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332

Query: 154 YEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCF 213
           Y+ ++A  C +CKK IT   +   +  WH  CF C AC+  +  + F   +   YC   +
Sbjct: 333 YDVRYAPSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDY 392

Query: 214 CDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
             ++  KC GC   I    G +++      WH+ CF C  C ++L G+ F +++D  LC
Sbjct: 393 EKMFGTKCHGCDFKID--AGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449



 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 6/172 (3%)

Query: 40  CEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSS 99
           C +C K I    + L      +H   F CSQC   L +  F  ++  + C  CY   Y+ 
Sbjct: 282 CHQCHKVIRG--RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339

Query: 100 KCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
            C +CKK I      M     +WH  CF C  C+ PI  ++F  ++   +C   YEK   
Sbjct: 340 SCAKCKKKIT--GEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFG 397

Query: 160 MQCVQCKKPITTGG--VTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
            +C  C   I  G   +      WH  CFVC  C+  L G+ F ++ D   C
Sbjct: 398 TKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLC 449



 Score = 88.6 bits (218), Expect = 6e-18
 Identities = 47/161 (29%), Positives = 74/161 (45%), Gaps = 7/161 (4%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F C  C + L    +   + + +C  C++  +A +C +C K I  +   +      WH
Sbjct: 304 EEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEI--MHALKMTWH 361

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
             CF C+ C+  + ++ F  +E    C   Y   + +KC  C   I  G R +E  G SW
Sbjct: 362 VHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSW 421

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCV 163
           H+TCF+C  CQ  +  K+F  K ++  C     K HA   V
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLC-----KSHAFSHV 457



 Score = 31.6 bits (70), Expect = 0.80
 Identities = 17/55 (30%), Positives = 23/55 (41%), Gaps = 4/55 (7%)

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDC 275
           C  C   I G    +Y+      +H + F C +C   L   GF  E+  I CP C
Sbjct: 282 CHQCHKVIRG----RYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPC 332


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  105 bits (262), Expect = 4e-23
 Identities = 51/154 (33%), Positives = 73/154 (47%), Gaps = 2/154 (1%)

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
           G SWH   F C  C+  +    F+ +    +C  CYEK  A +C +C++ I    ++  +
Sbjct: 327 GKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALK 386

Query: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
           Q WH  CFVC AC K +    F   D   YC   +  L+   C GC  PI    G  ++ 
Sbjct: 387 QTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIE--AGDMFLE 444

Query: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
                WH+ CF C  C  SL G+ F +++D  LC
Sbjct: 445 ALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478



 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 44/153 (28%), Positives = 72/153 (47%), Gaps = 4/153 (2%)

Query: 59  RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
           + WH   F+C+ C+N++    F  ++  L C  CY   ++ +C  C++ I+     +   
Sbjct: 328 KSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKIL--GEVISAL 385

Query: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
             +WH +CF+C  C +PI    F  +D + +C   Y       C  C+ PI  G +    
Sbjct: 386 KQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEA 445

Query: 179 --QPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
               WH  CFVC+ C + L GQ F ++ D   C
Sbjct: 446 LGYTWHDTCFVCSVCCESLEGQTFFSKKDKPLC 478



 Score = 87.0 bits (214), Expect = 2e-17
 Identities = 43/157 (27%), Positives = 76/157 (48%), Gaps = 7/157 (4%)

Query: 3   ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
           E F+C HC  ++    ++  + + YC +C+E  FA  C  C + I  +   +S   + WH
Sbjct: 333 EEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPECGRCQRKILGEV--ISALKQTWH 390

Query: 63  EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
            +CF C  C   + +  F  ++ +  C   Y   + + C  C+  I  G   +E  G +W
Sbjct: 391 VSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTW 450

Query: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
           H+TCF+C  C + +  ++F  K ++  C     K+HA
Sbjct: 451 HDTCFVCSVCCESLEGQTFFSKKDKPLC-----KKHA 482



 Score = 52.4 bits (124), Expect = 4e-07
 Identities = 29/111 (26%), Positives = 43/111 (38%), Gaps = 4/111 (3%)

Query: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
           C  C + I    +    + WH E F C  C+  ++   F       YC  C+   +A +C
Sbjct: 311 CAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAPEC 370

Query: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
             C   I G    + IS  ++ WH  CF C  C   +    F  E  +  C
Sbjct: 371 GRCQRKILG----EVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 417



 Score = 34.7 bits (78), Expect = 0.095
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 13/66 (19%)

Query: 221 CAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC-------- 272
           CA C   I G     ++    + WH + FNC  C  ++   GF+ E+  + C        
Sbjct: 311 CAHCNQVIRG----PFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFF 366

Query: 273 -PDCGK 277
            P+CG+
Sbjct: 367 APECGR 372


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.494 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,928,616
Number of Sequences: 37866
Number of extensions: 673708
Number of successful extensions: 11354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 423
Number of HSP's successfully gapped in prelim test: 471
Number of HSP's that attempted gapping in prelim test: 2388
Number of HSP's gapped (non-prelim): 3431
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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