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Search of human proteins with 41872557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
(555 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 1162 0.0
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 1144 0.0
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 1144 0.0
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 1144 0.0
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 1144 0.0
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 1144 0.0
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 585 e-167
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 585 e-167
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 585 e-167
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho... 163 3e-40
gi|6912724 tolloid-like 2 [Homo sapiens] 155 1e-37
gi|22547221 tolloid-like 1 [Homo sapiens] 152 6e-37
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom... 151 2e-36
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom... 150 3e-36
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom... 150 3e-36
gi|31317224 EGF-like repeats and discoidin I-like domains-contai... 147 2e-35
gi|126091152 cubilin [Homo sapiens] 145 7e-35
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens] 140 2e-33
gi|72384339 CUB domain containing protein 2 [Homo sapiens] 137 3e-32
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 134 3e-31
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens] 131 2e-30
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 128 2e-29
gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo sa... 128 2e-29
gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Ho... 125 8e-29
gi|105990535 coagulation factor V precursor [Homo sapiens] 124 3e-28
gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Ho... 120 3e-27
gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre... 113 5e-25
gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre... 113 5e-25
gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo sap... 110 4e-24
gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo sa... 110 4e-24
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 1162 bits (3007), Expect = 0.0
Identities = 555/555 (100%), Positives = 555/555 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKVGCSWRPL 555
PRTQQPKVGCSWRPL
Sbjct: 541 PRTQQPKVGCSWRPL 555
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 1144 bits (2958), Expect = 0.0
Identities = 547/548 (99%), Positives = 548/548 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKV 548
PRTQQPK+
Sbjct: 541 PRTQQPKL 548
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/203 (31%), Positives = 103/203 (50%), Gaps = 21/203 (10%)
Query: 248 TFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQ 307
T+H+ +A+ + F R + + C+ LGM SG IA+ QISASST + W+P
Sbjct: 413 TWHSGIALRLELFGCR--------VTDAPCSNMLGMLSGLIADSQISASST-QEYLWSPS 463
Query: 308 QSRLHGDDNGWTPNLDS---NKEYLQVDLRFLTMLTAIATQGAISRETQNGY----YVKS 360
+RL +GW P + +E+LQVDL + + QGA ++ +V+
Sbjct: 464 AARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRK 523
Query: 361 YKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWH-SG 417
+K+ S NG+DW + + K+F+ N + + P+ ++VR+ P+ W +G
Sbjct: 524 FKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG 582
Query: 418 IALRLELFGCRVTDA-PCSNMLG 439
I +RLE+ GC TD+ P LG
Sbjct: 583 IGMRLEVLGCDWTDSKPTVETLG 605
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 1144 bits (2958), Expect = 0.0
Identities = 547/548 (99%), Positives = 548/548 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKV 548
PRTQQPK+
Sbjct: 541 PRTQQPKL 548
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/203 (31%), Positives = 103/203 (50%), Gaps = 21/203 (10%)
Query: 248 TFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQ 307
T+H+ +A+ + F R + + C+ LGM SG IA+ QISASST + W+P
Sbjct: 413 TWHSGIALRLELFGCR--------VTDAPCSNMLGMLSGLIADSQISASST-QEYLWSPS 463
Query: 308 QSRLHGDDNGWTPNLDS---NKEYLQVDLRFLTMLTAIATQGAISRETQNGY----YVKS 360
+RL +GW P + +E+LQVDL + + QGA ++ +V+
Sbjct: 464 AARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRK 523
Query: 361 YKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWH-SG 417
+K+ S NG+DW + + K+F+ N + + P+ ++VR+ P+ W +G
Sbjct: 524 FKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG 582
Query: 418 IALRLELFGCRVTDA-PCSNMLG 439
I +RLE+ GC TD+ P LG
Sbjct: 583 IGMRLEVLGCDWTDSKPTVETLG 605
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 1144 bits (2958), Expect = 0.0
Identities = 547/548 (99%), Positives = 548/548 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKV 548
PRTQQPK+
Sbjct: 541 PRTQQPKL 548
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/203 (31%), Positives = 103/203 (50%), Gaps = 21/203 (10%)
Query: 248 TFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQ 307
T+H+ +A+ + F R + + C+ LGM SG IA+ QISASST + W+P
Sbjct: 413 TWHSGIALRLELFGCR--------VTDAPCSNMLGMLSGLIADSQISASST-QEYLWSPS 463
Query: 308 QSRLHGDDNGWTPNLDS---NKEYLQVDLRFLTMLTAIATQGAISRETQNGY----YVKS 360
+RL +GW P + +E+LQVDL + + QGA ++ +V+
Sbjct: 464 AARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRK 523
Query: 361 YKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWH-SG 417
+K+ S NG+DW + + K+F+ N + + P+ ++VR+ P+ W +G
Sbjct: 524 FKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG 582
Query: 418 IALRLELFGCRVTDA-PCSNMLG 439
I +RLE+ GC TD+ P LG
Sbjct: 583 IGMRLEVLGCDWTDSKPTVETLG 605
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 1144 bits (2958), Expect = 0.0
Identities = 547/548 (99%), Positives = 548/548 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKV 548
PRTQQPK+
Sbjct: 541 PRTQQPKL 548
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/203 (31%), Positives = 103/203 (50%), Gaps = 21/203 (10%)
Query: 248 TFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQ 307
T+H+ +A+ + F R + + C+ LGM SG IA+ QISASST + W+P
Sbjct: 413 TWHSGIALRLELFGCR--------VTDAPCSNMLGMLSGLIADSQISASST-QEYLWSPS 463
Query: 308 QSRLHGDDNGWTPNLDS---NKEYLQVDLRFLTMLTAIATQGAISRETQNGY----YVKS 360
+RL +GW P + +E+LQVDL + + QGA ++ +V+
Sbjct: 464 AARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRK 523
Query: 361 YKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWH-SG 417
+K+ S NG+DW + + K+F+ N + + P+ ++VR+ P+ W +G
Sbjct: 524 FKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG 582
Query: 418 IALRLELFGCRVTDA-PCSNMLG 439
I +RLE+ GC TD+ P LG
Sbjct: 583 IGMRLEVLGCDWTDSKPTVETLG 605
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 1144 bits (2958), Expect = 0.0
Identities = 547/548 (99%), Positives = 548/548 (100%)
Query: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY
Sbjct: 1 MDMFPLTWVFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
Query: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML
Sbjct: 61 APEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSML 120
Query: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL
Sbjct: 121 YIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTIL 180
Query: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS
Sbjct: 181 AKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRS 240
Query: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS
Sbjct: 241 STGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
Query: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS
Sbjct: 301 DGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKS 360
Query: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL
Sbjct: 361 YKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIAL 420
Query: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ
Sbjct: 421 RLELFGCRVTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRSGWFPRIPQ 480
Query: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD
Sbjct: 481 AQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQD 540
Query: 541 PRTQQPKV 548
PRTQQPK+
Sbjct: 541 PRTQQPKL 548
Score = 86.7 bits (213), Expect = 5e-17
Identities = 63/203 (31%), Positives = 103/203 (50%), Gaps = 21/203 (10%)
Query: 248 TFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQ 307
T+H+ +A+ + F R + + C+ LGM SG IA+ QISASST + W+P
Sbjct: 413 TWHSGIALRLELFGCR--------VTDAPCSNMLGMLSGLIADSQISASST-QEYLWSPS 463
Query: 308 QSRLHGDDNGWTPNLDS---NKEYLQVDLRFLTMLTAIATQGAISRETQNGY----YVKS 360
+RL +GW P + +E+LQVDL + + QGA ++ +V+
Sbjct: 464 AARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRK 523
Query: 361 YKLEVSTNGEDWMVYRHGKNH--KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWH-SG 417
+K+ S NG+DW + + K+F+ N + + P+ ++VR+ P+ W +G
Sbjct: 524 FKVSYSLNGKDWEYIQDPRTQQPKLFEGNMHYDTPDIRRFD-PIPAQYVRVYPERWSPAG 582
Query: 418 IALRLELFGCRVTDA-PCSNMLG 439
I +RLE+ GC TD+ P LG
Sbjct: 583 IGMRLEVLGCDWTDSKPTVETLG 605
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 585 bits (1508), Expect = e-167
Identities = 275/521 (52%), Positives = 373/521 (71%), Gaps = 10/521 (1%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG + + GY+TSPGYP Y + CEW++ AP+P Q+I++NFNPHF++E DCKYD+
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147
+E+ DG++E+ GK CG IAPP ++SSG L+IKF SDY GAGFS+RYEIFK G E
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 148 DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
CS+N+T+P+G I+SPGFPEKYP++L+CT+ + A EIIL+F FDLE D G
Sbjct: 147 -CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
C+YD L+IWDG P VGP IG+YCG KTP +RSS+GILS+ F+TD A+AK+GFSA Y ++
Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Query: 268 HQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKE 327
E+F+C LGMESG I ++QI+ASS YS W+ ++SRL+ +NGWTP DS +E
Sbjct: 266 QSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN-WSAERSRLNYPENGWTPGEDSYRE 324
Query: 328 YLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQAN 387
++QVDL L +TA+ TQGAIS+ET+ YYVK+YK++VS+NGEDW+ + G +FQ N
Sbjct: 325 WIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGN 384
Query: 388 NDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIAD 447
+ T+VV+ PL+TRFVRI+P TW +GI++R E++GC++TD PCS MLGM+SGLI+D
Sbjct: 385 TNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISD 444
Query: 448 SQISASSTQEYLWSPSAARLVSSRSGW-FPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGA 506
SQI++S+ + W P RLV+SRSGW P P + EWLQ+DLG K V+G+IIQG
Sbjct: 445 SQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIIIQGG 503
Query: 507 RGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
+ E + F+RKFK+ YS NG DW+ I D ++ K
Sbjct: 504 KHR------ENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAK 538
Score = 133 bits (334), Expect = 5e-31
Identities = 126/449 (28%), Positives = 198/449 (44%), Gaps = 74/449 (16%)
Query: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-------CKYDFIE 89
+G I SPG+P+ YP+ C +IV+AP+ ++ I+L F F++E C+YD +E
Sbjct: 155 SGVIKSPGFPEKYPNSLECTYIVFAPKMSE-IILEFES-FDLEPDSNPPGGMFCRYDRLE 212
Query: 90 IRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG-SED 148
I DG + +G++CG P I SS +L + F +D A GFS Y + ++ SED
Sbjct: 213 IWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Query: 149 --CSKNFTSPNGTIESPGFP--EKYPHNLDCTFTILAKPK-------------------- 184
C + +G I S +Y N + L P+
Sbjct: 273 FKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGL 332
Query: 185 --------------MEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYC 230
E ++ + + D GE DW+ I +G V +
Sbjct: 333 LRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGE-----DWITIKEGNKPV-----LFQ 382
Query: 231 GTKTPSELRSST---GILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGR 287
G P+++ + +++ A + G S R+ V+ + ++ C+ LGM SG
Sbjct: 383 GNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE-VYGCKITDYPCSGMLGMVSGL 441
Query: 288 IANEQISASSTYSDGRWTPQQSRLHGDDNGWT----PNLDSNKEYLQVDLRFLTMLTAIA 343
I++ QI+ SS D W P+ RL +GW P+ N E+LQ+DL ++ I
Sbjct: 442 ISDSQIT-SSNQGDRNWMPENIRLVTSRSGWALPPAPHSYIN-EWLQIDLGEEKIVRGII 499
Query: 344 TQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKV--FQANNDATEVVLNKLHAP 401
QG RE N +++ +K+ S NG DW + K F+ NN+ L A
Sbjct: 500 IQGGKHRE--NKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPA- 556
Query: 402 LLTRFVRIRPQ-TWHSGIALRLELFGCRV 429
L TRF+RI P+ H G+ LR+EL GC V
Sbjct: 557 LSTRFIRIYPERATHGGLGLRMELLGCEV 585
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 585 bits (1508), Expect = e-167
Identities = 275/521 (52%), Positives = 373/521 (71%), Gaps = 10/521 (1%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG + + GY+TSPGYP Y + CEW++ AP+P Q+I++NFNPHF++E DCKYD+
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147
+E+ DG++E+ GK CG IAPP ++SSG L+IKF SDY GAGFS+RYEIFK G E
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 148 DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
CS+N+T+P+G I+SPGFPEKYP++L+CT+ + A EIIL+F FDLE D G
Sbjct: 147 -CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
C+YD L+IWDG P VGP IG+YCG KTP +RSS+GILS+ F+TD A+AK+GFSA Y ++
Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Query: 268 HQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKE 327
E+F+C LGMESG I ++QI+ASS YS W+ ++SRL+ +NGWTP DS +E
Sbjct: 266 QSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN-WSAERSRLNYPENGWTPGEDSYRE 324
Query: 328 YLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQAN 387
++QVDL L +TA+ TQGAIS+ET+ YYVK+YK++VS+NGEDW+ + G +FQ N
Sbjct: 325 WIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGN 384
Query: 388 NDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIAD 447
+ T+VV+ PL+TRFVRI+P TW +GI++R E++GC++TD PCS MLGM+SGLI+D
Sbjct: 385 TNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISD 444
Query: 448 SQISASSTQEYLWSPSAARLVSSRSGW-FPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGA 506
SQI++S+ + W P RLV+SRSGW P P + EWLQ+DLG K V+G+IIQG
Sbjct: 445 SQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIIIQGG 503
Query: 507 RGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
+ E + F+RKFK+ YS NG DW+ I D ++ K
Sbjct: 504 KHR------ENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAK 538
Score = 133 bits (335), Expect = 4e-31
Identities = 128/453 (28%), Positives = 201/453 (44%), Gaps = 75/453 (16%)
Query: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-------CKYDFIE 89
+G I SPG+P+ YP+ C +IV+AP+ ++ I+L F F++E C+YD +E
Sbjct: 155 SGVIKSPGFPEKYPNSLECTYIVFAPKMSE-IILEFES-FDLEPDSNPPGGMFCRYDRLE 212
Query: 90 IRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG-SED 148
I DG + +G++CG P I SS +L + F +D A GFS Y + ++ SED
Sbjct: 213 IWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Query: 149 --CSKNFTSPNGTIESPGFP--EKYPHNLDCTFTILAKPK-------------------- 184
C + +G I S +Y N + L P+
Sbjct: 273 FKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGL 332
Query: 185 --------------MEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYC 230
E ++ + + D GE DW+ I +G V +
Sbjct: 333 LRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGE-----DWITIKEGNKPV-----LFQ 382
Query: 231 GTKTPSELRSST---GILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGR 287
G P+++ + +++ A + G S R+ V+ + ++ C+ LGM SG
Sbjct: 383 GNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE-VYGCKITDYPCSGMLGMVSGL 441
Query: 288 IANEQISASSTYSDGRWTPQQSRLHGDDNGWT----PNLDSNKEYLQVDLRFLTMLTAIA 343
I++ QI+ SS D W P+ RL +GW P+ N E+LQ+DL ++ I
Sbjct: 442 ISDSQIT-SSNQGDRNWMPENIRLVTSRSGWALPPAPHSYIN-EWLQIDLGEEKIVRGII 499
Query: 344 TQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKV--FQANNDATEVVLNKLHAP 401
QG RE N +++ +K+ S NG DW + K F+ NN+ L A
Sbjct: 500 IQGGKHRE--NKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPA- 556
Query: 402 LLTRFVRIRPQ-TWHSGIALRLELFGCRVTDAP 433
L TRF+RI P+ H G+ LR+EL GC V +AP
Sbjct: 557 LSTRFIRIYPERATHGGLGLRMELLGCEV-EAP 588
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 585 bits (1508), Expect = e-167
Identities = 275/521 (52%), Positives = 373/521 (71%), Gaps = 10/521 (1%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG + + GY+TSPGYP Y + CEW++ AP+P Q+I++NFNPHF++E DCKYD+
Sbjct: 27 CGDTIKIESPGYLTSPGYPHSYHPSEKCEWLIQAPDPYQRIMINFNPHFDLEDRDCKYDY 86
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147
+E+ DG++E+ GK CG IAPP ++SSG L+IKF SDY GAGFS+RYEIFK G E
Sbjct: 87 VEVFDGENENGHFRGKFCGKIAPPPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKRGPE 146
Query: 148 DCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
CS+N+T+P+G I+SPGFPEKYP++L+CT+ + A EIIL+F FDLE D G
Sbjct: 147 -CSQNYTTPSGVIKSPGFPEKYPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMF 205
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
C+YD L+IWDG P VGP IG+YCG KTP +RSS+GILS+ F+TD A+AK+GFSA Y ++
Sbjct: 206 CRYDRLEIWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVL 265
Query: 268 HQEPLENFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDSNKE 327
E+F+C LGMESG I ++QI+ASS YS W+ ++SRL+ +NGWTP DS +E
Sbjct: 266 QSSVSEDFKCMEALGMESGEIHSDQITASSQYSTN-WSAERSRLNYPENGWTPGEDSYRE 324
Query: 328 YLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQAN 387
++QVDL L +TA+ TQGAIS+ET+ YYVK+YK++VS+NGEDW+ + G +FQ N
Sbjct: 325 WIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVLFQGN 384
Query: 388 NDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIAD 447
+ T+VV+ PL+TRFVRI+P TW +GI++R E++GC++TD PCS MLGM+SGLI+D
Sbjct: 385 TNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKITDYPCSGMLGMVSGLISD 444
Query: 448 SQISASSTQEYLWSPSAARLVSSRSGW-FPRIPQAQPGEEWLQVDLGTPKTVKGVIIQGA 506
SQI++S+ + W P RLV+SRSGW P P + EWLQ+DLG K V+G+IIQG
Sbjct: 445 SQITSSNQGDRNWMPENIRLVTSRSGWALPPAPHSYI-NEWLQIDLGEEKIVRGIIIQGG 503
Query: 507 RGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPK 547
+ E + F+RKFK+ YS NG DW+ I D ++ K
Sbjct: 504 KHR------ENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAK 538
Score = 133 bits (335), Expect = 4e-31
Identities = 128/453 (28%), Positives = 201/453 (44%), Gaps = 75/453 (16%)
Query: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-------CKYDFIE 89
+G I SPG+P+ YP+ C +IV+AP+ ++ I+L F F++E C+YD +E
Sbjct: 155 SGVIKSPGFPEKYPNSLECTYIVFAPKMSE-IILEFES-FDLEPDSNPPGGMFCRYDRLE 212
Query: 90 IRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG-SED 148
I DG + +G++CG P I SS +L + F +D A GFS Y + ++ SED
Sbjct: 213 IWDGFPDVGPHIGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSED 272
Query: 149 --CSKNFTSPNGTIESPGFP--EKYPHNLDCTFTILAKPK-------------------- 184
C + +G I S +Y N + L P+
Sbjct: 273 FKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGL 332
Query: 185 --------------MEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYC 230
E ++ + + D GE DW+ I +G V +
Sbjct: 333 LRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGE-----DWITIKEGNKPV-----LFQ 382
Query: 231 GTKTPSELRSST---GILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCNVPLGMESGR 287
G P+++ + +++ A + G S R+ V+ + ++ C+ LGM SG
Sbjct: 383 GNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFE-VYGCKITDYPCSGMLGMVSGL 441
Query: 288 IANEQISASSTYSDGRWTPQQSRLHGDDNGWT----PNLDSNKEYLQVDLRFLTMLTAIA 343
I++ QI+ SS D W P+ RL +GW P+ N E+LQ+DL ++ I
Sbjct: 442 ISDSQIT-SSNQGDRNWMPENIRLVTSRSGWALPPAPHSYIN-EWLQIDLGEEKIVRGII 499
Query: 344 TQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKV--FQANNDATEVVLNKLHAP 401
QG RE N +++ +K+ S NG DW + K F+ NN+ L A
Sbjct: 500 IQGGKHRE--NKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEGNNNYDTPELRTFPA- 556
Query: 402 LLTRFVRIRPQ-TWHSGIALRLELFGCRVTDAP 433
L TRF+RI P+ H G+ LR+EL GC V +AP
Sbjct: 557 LSTRFIRIYPERATHGGLGLRMELLGCEV-EAP 588
>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
sapiens]
Length = 387
Score = 163 bits (413), Expect = 3e-40
Identities = 101/286 (35%), Positives = 156/286 (54%), Gaps = 24/286 (8%)
Query: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329
+C PLG+E+G IAN QI+ASS W P+ +RL+ G N WTP+ + + ++
Sbjct: 69 KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
Query: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388
QV+L +T + TQGA + Y+K++K+ S NG ++ ++ K HK F N
Sbjct: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
Query: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448
+ V +N P+ ++VR+ P + H+ LR EL GC + C+N LG+ + I D
Sbjct: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
Query: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502
QI+ASS+ + + W+PS ARL + + + + ++WLQVDLG+ K V G+I
Sbjct: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQVDLGSSKEVTGII 303
Query: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKV 548
QGAR S+ FV +KV+YS + +W QDPRT K+
Sbjct: 304 TQGARNFGSV------QFVASYKVAYSNDSANWTEYQDPRTGSSKI 343
Score = 99.8 bits (247), Expect = 6e-21
Identities = 61/160 (38%), Positives = 85/160 (53%), Gaps = 11/160 (6%)
Query: 277 CNVPLGMESGRIANEQISASSTYSDG-----RWTPQQSRL--HGDDNGWTPNLDSNKEYL 329
C PLG+++ I ++QI+ASS+Y W P +RL G+ N W N ++L
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKTWGLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWL 289
Query: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGK--NHKVFQAN 387
QVDL +T I TQGA R + +V SYK+ S + +W Y+ + + K+F N
Sbjct: 290 QVDLGSSKEVTGIITQGA--RNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGN 347
Query: 388 NDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427
D N P+L R+VRI P WH+ IALRLEL GC
Sbjct: 348 WDNHSHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387
Score = 61.6 bits (148), Expect = 2e-09
Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 14/128 (10%)
Query: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484
+ C LG+ +G IA+SQI+ASS + W P ARL +R+G P +
Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
Query: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
W+QV+L V GV+ QGA + + + +++ FKV+YSLNG ++++I D +
Sbjct: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDVNKK 178
Query: 545 QPKVGCSW 552
+ +W
Sbjct: 179 HKEFVGNW 186
>gi|6912724 tolloid-like 2 [Homo sapiens]
Length = 1015
Score = 155 bits (391), Expect = 1e-37
Identities = 93/276 (33%), Positives = 140/276 (50%), Gaps = 47/276 (17%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG +N KDAG I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 464 CGGDMN-KDAGQIQSPNYPDDYRPSKECVWRITVSE-GFHVGLTFQA-FEIERHDSCAYD 520
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY--EIFKT 144
++E+RDG +E + L+G CG P + SS + L++KF SD + AGF+ + E+ +
Sbjct: 521 YLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDEC 580
Query: 145 GSED-----------------------------------CSKNFTSPNGTIESPGFPEKY 169
D C T NGTI SPG+P++Y
Sbjct: 581 SWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKLNGTITSPGWPKEY 640
Query: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
P N +C + ++A + I LQF +F+LE G CKYD++++ G+ L G++
Sbjct: 641 PTNKNCVWQVVAPAQYRISLQFEVFELE------GNDVCKYDFVEVRSGLSPDAKLHGRF 694
Query: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
CG++TP + S + + + F +D V+K GF A ++
Sbjct: 695 CGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFF 730
Score = 146 bits (368), Expect = 6e-35
Identities = 80/241 (33%), Positives = 126/241 (52%), Gaps = 16/241 (6%)
Query: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
P CG L G ++PG+P YPS+ +C W + + P +KIVLNF + C Y
Sbjct: 349 PACGETLQDT-TGNFSAPGFPNGYPSYSHCVWRI-SVTPGEKIVLNFTSMDLFKSRLCWY 406
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D++E+RDG A LLG+ CG+ P ++S+ S L+++F S G GF YE
Sbjct: 407 DYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYE----- 461
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
C + G I+SP +P+ Y + +C + I + L F F++E HD
Sbjct: 462 -ATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHD----- 515
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD+L++ DG LIG +CG + P +++SS+ L + F +D ++ K GF+A +
Sbjct: 516 --SCAYDYLEVRDGPTEESALIGHFCGYEKPEDVKSSSNRLWMKFVSDGSINKAGFAANF 573
Query: 265 Y 265
+
Sbjct: 574 F 574
Score = 142 bits (358), Expect = 8e-34
Identities = 87/273 (31%), Positives = 136/273 (49%), Gaps = 47/273 (17%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + +K G ITSPG+P++YP+++NC W V AP +I L F FE+E +D CKYD
Sbjct: 620 CGGFI-TKLNGTITSPGWPKEYPTNKNCVWQVVAPA-QYRISLQFEV-FELEGNDVCKYD 676
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR-------- 138
F+E+R G S A L G+ CG+ P I S + + ++F SD GF
Sbjct: 677 FVEVRSGLSPDAKLHGRFCGSETPEVITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDEC 736
Query: 139 -------------------------YEIFKTGSE----DCSKNFTSPNGTIESPGFPEKY 169
Y + + G + C+ +S GT+ SP +P+KY
Sbjct: 737 AKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKY 796
Query: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
P +CT+ I + + L F F++E +C YD L+++DG + P++G++
Sbjct: 797 PSRRECTWNISSTAGHRVKLTFNEFEIEQ------HQECAYDHLEMYDGPDSLAPILGRF 850
Query: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
CG+K P +S + L F++D +V + GF A
Sbjct: 851 CGSKKPDPTVASGSSMFLRFYSDASVQRKGFQA 883
Score = 129 bits (324), Expect = 7e-30
Identities = 76/242 (31%), Positives = 123/242 (50%), Gaps = 20/242 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
C +++S + G + SP +P YPS + C W + + ++ L FN FEIE+H +C YD
Sbjct: 776 CAHKISSVE-GTLASPNWPDKYPSRRECTWNI-SSTAGHRVKLTFN-EFEIEQHQECAYD 832
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
+E+ DG A +LG+ CG+ P ++SGS ++++F SD + Q GF + S
Sbjct: 833 HLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFYSDASVQRKGFQAVH------S 886
Query: 147 EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
+C + T E + YP C + I+A+ + L F F++E
Sbjct: 887 TECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGVELTFRTFEVEE---- 942
Query: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
E DC YD+++ +DG P +G++CG+ E+ S+ L + F TD + K GF A
Sbjct: 943 --EADCGYDYMEAYDGYDSSAPRLGRFCGSGPLEEIYSAGDSLMIRFRTDDTINKKGFHA 1000
Query: 263 RY 264
RY
Sbjct: 1001 RY 1002
>gi|22547221 tolloid-like 1 [Homo sapiens]
Length = 1013
Score = 152 bits (385), Expect = 6e-37
Identities = 91/278 (32%), Positives = 136/278 (48%), Gaps = 51/278 (18%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + K+ G I SP YP DY + C W + E + + L F FEIE+HD C YD
Sbjct: 462 CGGEIR-KNEGQIQSPNYPDDYRPMKECVWKITVSE-SYHVGLTFQS-FEIERHDNCAYD 518
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
++E+RDG SE++ L+G+ CG P I S+ + L++KF SD AGF+ + FK
Sbjct: 519 YLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF--FKEED 576
Query: 147 E---------------------------------------DCSKNFTSPNGTIESPGFPE 167
E C T NGTI +PG+P+
Sbjct: 577 ECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGTITTPGWPK 636
Query: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
+YP N +C + ++A + I ++F F+LE G CKYD+++IW G+ L G
Sbjct: 637 EYPPNKNCVWQVVAPTQYRISVKFEFFELE------GNEVCKYDYVEIWSGLSSESKLHG 690
Query: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
K+CG + P + S + + F +D V+K GF A ++
Sbjct: 691 KFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFF 728
Score = 150 bits (379), Expect = 3e-36
Identities = 85/246 (34%), Positives = 128/246 (52%), Gaps = 16/246 (6%)
Query: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
P CG L + G ++SPG+P YPS+ +C W V + P +KIVLNF + C Y
Sbjct: 347 PACGETLQESN-GNLSSPGFPNGYPSYTHCIWRV-SVTPGEKIVLNFTTMDLYKSSLCWY 404
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D+IE+RDG + LLG+ CG+ P + S+ S ++I+F S G GF+ YE
Sbjct: 405 DYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEAI--- 461
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
C G I+SP +P+ Y +C + I + L F F++E HD
Sbjct: 462 ---CGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHD----- 513
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
+C YD+L++ DG PLIG++CG P ++RS++ L + F +D V K GF+A +
Sbjct: 514 --NCAYDYLEVRDGTSENSPLIGRFCGYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANF 571
Query: 265 YLVHQE 270
+ E
Sbjct: 572 FKEEDE 577
Score = 142 bits (357), Expect = 1e-33
Identities = 81/257 (31%), Positives = 140/257 (54%), Gaps = 23/257 (8%)
Query: 13 LYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNF 72
L+ ++H + + C +++S +G ITSP +P YPS + C W + A P +I L F
Sbjct: 762 LHDNKHDCK---EAECEQKIHSP-SGLITSPNWPDKYPSRKECTWEISAT-PGHRIKLAF 816
Query: 73 NPHFEIEKH-DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQ 131
+ FEIE+H +C YD +E+ DG++E + +LG+ CGN P ++++G+ ++++F SD + Q
Sbjct: 817 S-EFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFVSDASVQ 875
Query: 132 GAGFSLRYEIFKTGSEDCS---KNFTSPNGTIESPGFPE-KYPHNLDCTFTILAKPKMEI 187
GF T S +C K + P F + YP +DC + ++++ +
Sbjct: 876 RKGFQ------ATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRL 929
Query: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSL 247
L F F++E E DC YD+++++DG+ +G++CG+ P E+ S + +
Sbjct: 930 ELSFQTFEVEE------EADCGYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLI 983
Query: 248 TFHTDMAVAKDGFSARY 264
FHTD + K GF RY
Sbjct: 984 HFHTDDTINKKGFHIRY 1000
Score = 135 bits (340), Expect = 1e-31
Identities = 90/275 (32%), Positives = 133/275 (48%), Gaps = 47/275 (17%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG L +K G IT+PG+P++YP ++NC W V AP +I + F FE+E ++ CKYD
Sbjct: 618 CGGLL-TKLNGTITTPGWPKEYPPNKNCVWQVVAPT-QYRISVKFE-FFELEGNEVCKYD 674
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY------- 139
++EI G S + L GK CG P I S + + I+F SD GF +
Sbjct: 675 YVEIWSGLSSESKLHGKFCGAEVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDEC 734
Query: 140 ---------EIFKT-GS--------------------EDCSKNFTSPNGTIESPGFPEKY 169
E T GS +C + SP+G I SP +P+KY
Sbjct: 735 SKDNGGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPDKY 794
Query: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
P +CT+ I A P I L F F++E +C YD L+++DG P++G+
Sbjct: 795 PSRKECTWEISATPGHRIKLAFSEFEIEQ------HQECAYDHLEVFDGETEKSPILGRL 848
Query: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
CG K P L ++ + + F +D +V + GF A +
Sbjct: 849 CGNKIPDPLVATGNKMFVRFVSDASVQRKGFQATH 883
Score = 67.0 bits (162), Expect = 4e-11
Identities = 40/117 (34%), Positives = 63/117 (53%), Gaps = 6/117 (5%)
Query: 28 CGGRLNSKDAG---YITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DC 83
CGGRL ++ Y + +YP +CEW++ + E ++ L+F FE+E+ DC
Sbjct: 887 CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVS-ERGSRLELSFQT-FEVEEEADC 944
Query: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYE 140
YD++E+ DG +A LG+ CG+ P I S G + I F +D GF +RY+
Sbjct: 945 GYDYVELFDGLDSTAVGLGRFCGSGPPEEIYSIGDSVLIHFHTDDTINKKGFHIRYK 1001
>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
sapiens]
Length = 823
Score = 151 bits (381), Expect = 2e-36
Identities = 96/280 (34%), Positives = 142/280 (50%), Gaps = 51/280 (18%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Query: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
GS CS + T NG+I SPG+P+
Sbjct: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
Query: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
Query: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
K+CG++ P + S + + F +D V+K GF A ++ V
Sbjct: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSV 703
Score = 138 bits (347), Expect = 2e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Query: 265 Y 265
+
Sbjct: 545 F 545
Score = 83.2 bits (204), Expect = 6e-16
Identities = 49/122 (40%), Positives = 70/122 (57%), Gaps = 4/122 (3%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
F+E+R G + + L GK CG+ P I S + + ++F SD GF + G+
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLEGA 707
Query: 147 ED 148
D
Sbjct: 708 GD 709
>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
sapiens]
Length = 730
Score = 150 bits (379), Expect = 3e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Query: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
GS CS + T NG+I SPG+P+
Sbjct: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
Query: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
Query: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
Score = 138 bits (347), Expect = 2e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Query: 265 Y 265
+
Sbjct: 545 F 545
>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
sapiens]
Length = 986
Score = 150 bits (379), Expect = 3e-36
Identities = 95/278 (34%), Positives = 141/278 (50%), Gaps = 51/278 (18%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + KD G+I SP YP DY + C W + E + L F FEIE+HD C YD
Sbjct: 435 CGGDVK-KDYGHIQSPNYPDDYRPSKVCIWRIQVSE-GFHVGLTFQS-FEIERHDSCAYD 491
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK--- 143
++E+RDG SES+ L+G++CG P I S+ S L++KF SD + AGF++ + FK
Sbjct: 492 YLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF--FKEVD 549
Query: 144 -----------------TGSEDCSKN-------------------FTSPNGTIESPGFPE 167
GS CS + T NG+I SPG+P+
Sbjct: 550 ECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPK 609
Query: 168 KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG 227
+YP N +C + ++A + I LQF F+ E G CKYD++++ G+ L G
Sbjct: 610 EYPPNKNCIWQLVAPTQYRISLQFDFFETE------GNDVCKYDFVEVRSGLTADSKLHG 663
Query: 228 KYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYY 265
K+CG++ P + S + + F +D V+K GF A ++
Sbjct: 664 KFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFF 701
Score = 145 bits (367), Expect = 7e-35
Identities = 91/275 (33%), Positives = 139/275 (50%), Gaps = 47/275 (17%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG L +K G ITSPG+P++YP ++NC W + AP +I L F+ FE E +D CKYD
Sbjct: 591 CGGFL-TKLNGSITSPGWPKEYPPNKNCIWQLVAPT-QYRISLQFD-FFETEGNDVCKYD 647
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY-----EI 141
F+E+R G + + L GK CG+ P I S + + ++F SD GF + E
Sbjct: 648 FVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDEC 707
Query: 142 FKTGS---EDCSKNF-----------------------------TSPNGTIESPGFPEKY 169
K +DC F TS +GTI SP +P+KY
Sbjct: 708 SKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKY 767
Query: 170 PHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKY 229
P +CT+ I + P + L F+ D+E P +C YD L+++DG P++G++
Sbjct: 768 PSKKECTWAISSTPGHRVKLTFMEMDIESQP------ECAYDHLEVFDGRDAKAPVLGRF 821
Query: 230 CGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
CG+K P + ++ + L F++D +V + GF A +
Sbjct: 822 CGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH 856
Score = 138 bits (347), Expect = 2e-32
Identities = 81/241 (33%), Positives = 124/241 (51%), Gaps = 16/241 (6%)
Query: 26 PPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY 85
P CG L G +SP YP Y +H +C W + + P +KI+LNF C Y
Sbjct: 320 PACGETLQDS-TGNFSSPEYPNGYSAHMHCVWRI-SVTPGEKIILNFTSLDLYRSRLCWY 377
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D++E+RDG A L G+ CG+ P I+S+ S L+++F S G GF YE G
Sbjct: 378 DYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGG 437
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE-HDPLQVG 204
D K++ G I+SP +P+ Y + C + I + L F F++E HD
Sbjct: 438 --DVKKDY----GHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD----- 486
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD+L++ DG LIG+YCG + P +++S++ L L F +D ++ K GF+ +
Sbjct: 487 --SCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNF 544
Query: 265 Y 265
+
Sbjct: 545 F 545
Score = 129 bits (325), Expect = 5e-30
Identities = 69/232 (29%), Positives = 119/232 (51%), Gaps = 17/232 (7%)
Query: 37 AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSE 96
+G ITSP +P YPS + C W + + P ++ L F + +C YD +E+ DG
Sbjct: 755 SGTITSPNWPDKYPSKKECTWAI-SSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDA 813
Query: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
A +LG+ CG+ P ++++GS ++++F SD + Q GF + + +C +
Sbjct: 814 KAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASH------ATECGGQVRAD 867
Query: 157 NGTIESPGFPE----KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDW 212
T + + YP +DC + I+A+ + L F F++E E DC YD+
Sbjct: 868 VKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEE------ETDCGYDY 921
Query: 213 LDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
++++DG P +G+YCG+ P E+ S+ + + FH+D + K GF RY
Sbjct: 922 MELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY 973
>gi|31317224 EGF-like repeats and discoidin I-like
domains-containing protein 3 [Homo sapiens]
Length = 480
Score = 147 bits (371), Expect = 2e-35
Identities = 100/290 (34%), Positives = 150/290 (51%), Gaps = 29/290 (10%)
Query: 275 FQCNVPLGMESGRIANEQISASST----YSDGRWTPQQSRLH--GDDNGWTPNLDSNKEY 328
++C+ PLG+E G I+N+QI+ASST + +W P +RL+ G N WT + +
Sbjct: 156 YKCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKGLINAWTAAENDRWPW 215
Query: 329 LQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYR-HGKNH-KVFQA 386
+Q++L+ +T + TQGA + + Y+KSYK+ S +G+ W +Y+ G N VF+
Sbjct: 216 IQINLQRKMRVTGVITQGA--KRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTNEDMVFRG 273
Query: 387 NNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIA 446
N D N P+ ++VR+ PQ LR+EL GC ++ CS LGM SG I
Sbjct: 274 NIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELSG--CSEPLGMKSGHIQ 331
Query: 447 DSQISASS------TQEYLWSPSAARL--VSSRSGWFPRIPQAQPGEEWLQVDLGTPKTV 498
D QI+ASS + W P ARL + W +WLQVDL P V
Sbjct: 332 DYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAW---TSGHNDQSQWLQVDLLVPTKV 388
Query: 499 KGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKV 548
G+I QGA+ + FV +K++YS +G+ W QD + ++ KV
Sbjct: 389 TGIITQGAKDFGHV------QFVGSYKLAYSNDGEHWTVYQDEKQRKDKV 432
Score = 106 bits (264), Expect = 6e-23
Identities = 65/160 (40%), Positives = 88/160 (55%), Gaps = 11/160 (6%)
Query: 277 CNVPLGMESGRIANEQISASSTYSDGR-----WTPQQSRL--HGDDNGWTPNLDSNKEYL 329
C+ PLGM+SG I + QI+ASS + W P+++RL G N WT + ++L
Sbjct: 319 CSEPLGMKSGHIQDYQITASSIFRTLNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWL 378
Query: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK--VFQAN 387
QVDL T +T I TQGA ++ + +V SYKL S +GE W VY+ K K VFQ N
Sbjct: 379 QVDLLVPTKVTGIITQGA--KDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGN 436
Query: 388 NDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427
D N + P+ R +RI P +W+ I LR EL GC
Sbjct: 437 FDNDTHRKNVIDPPIYARHIRILPWSWYGRITLRSELLGC 476
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 145 bits (367), Expect = 7e-35
Identities = 85/246 (34%), Positives = 124/246 (50%), Gaps = 13/246 (5%)
Query: 21 RGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEK 80
R Q CGG + + ++SP +P +YP++QNC WI+ A P I L+F HFE+E+
Sbjct: 1613 RAQFRQACGGHILTSSFDTVSSPRFPANYPNNQNCSWIIQAQPPLNHITLSFT-HFELER 1671
Query: 81 H-DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
C DF+EI DG E A L G++CG P I S S L ++F SD + GF +
Sbjct: 1672 STTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFVSDSSISAGGF---H 1728
Query: 140 EIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHD 199
C F G SPG+P+ YP N++C + I++ P + L F+ F LE
Sbjct: 1729 TTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQLSFISFQLEDS 1788
Query: 200 PLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTG-ILSLTFHTDMAVAKD 258
DC D+++I +G G L+G+YCG P S G L + F +D + +
Sbjct: 1789 Q------DCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGT 1841
Query: 259 GFSARY 264
GF A +
Sbjct: 1842 GFQATF 1847
Score = 137 bits (346), Expect = 2e-32
Identities = 80/242 (33%), Positives = 123/242 (50%), Gaps = 18/242 (7%)
Query: 28 CGGRLNSKDA---GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHDC 83
CGG + DA GY+TSP +P +YP H +C WI+ AP P +I L F F+IE +C
Sbjct: 2217 CGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAP-PETRIQLQFEDRFDIEVTPNC 2275
Query: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
+++E+RDG A +L K CG P + SSG ++Y++F SD + GF +Y I
Sbjct: 2276 TSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDNSPTHVGFKAKYSI-- 2333
Query: 144 TGSEDCSKNFTSPNGTIESPGFPE-KYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202
C +G +ES G P Y NL C + + + + F F+L++
Sbjct: 2334 ---AQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLSGHYLTISFEDFNLQN---- 2386
Query: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
C+ D+++IWD G ++G+YCG P + +S+ + F TD +V GF
Sbjct: 2387 --SSGCEKDFVEIWDNHTS-GNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRL 2443
Query: 263 RY 264
R+
Sbjct: 2444 RF 2445
Score = 136 bits (342), Expect = 6e-32
Identities = 80/245 (32%), Positives = 126/245 (51%), Gaps = 19/245 (7%)
Query: 24 PDPPCGGRLNSKDAGY-ITSP--GYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEK 80
P CG L+ + + SP GY D NC W++ E + + + F F +E
Sbjct: 470 PQQVCGESLSGINGSFSYRSPDVGYVHDV----NCFWVIKT-EMGKVLRITFT-FFRLES 523
Query: 81 HD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRY 139
D C ++F+++ DGDS SA LG+ CG+ P ++SS + LY S++ R G GF++R+
Sbjct: 524 MDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLRNGRGFTVRW 583
Query: 140 EIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHD 199
E T +C T P G+I+SPG+P YP DC + ++ P + + F LEH
Sbjct: 584 E---TQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGTLSLEH- 639
Query: 200 PLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDG 259
DC D+L+I DG + PL+GK+C T + L+++ + FH+D ++ G
Sbjct: 640 -----HDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSDSQISDQG 694
Query: 260 FSARY 264
F Y
Sbjct: 695 FHITY 699
Score = 134 bits (337), Expect = 2e-31
Identities = 83/251 (33%), Positives = 129/251 (51%), Gaps = 25/251 (9%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY-- 85
CGG L++ D G ITSP YP+ YPS+ NC W V + I ++F F+I D
Sbjct: 2092 CGGYLHA-DRGIITSPKYPETYPSNLNCSWHVLV-QSGLTIAVHFEQPFQIPNGDSSCNQ 2149
Query: 86 -DFIEIRDGDSESADLLGK------HCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLR 138
D++ +R+G + LG CG+ A T+ +S + ++++F SD++ +G GF ++
Sbjct: 2150 GDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNEGQGFKIK 2209
Query: 139 YEIFKTGSEDCSKNF----TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFL-I 193
YE S C N G + SP P YP + DC + + A P+ I LQF
Sbjct: 2210 YE---AKSLACGGNVYIHDADSAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDR 2266
Query: 194 FDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDM 253
FD+E P +C ++L++ DG+ P++ K+CGT PS SS ++ L F +D
Sbjct: 2267 FDIEVTP------NCTSNYLELRDGVDSDAPILSKFCGTSLPSSQWSSGEVMYLRFRSDN 2320
Query: 254 AVAKDGFSARY 264
+ GF A+Y
Sbjct: 2321 SPTHVGFKAKY 2331
Score = 133 bits (335), Expect = 4e-31
Identities = 81/234 (34%), Positives = 121/234 (51%), Gaps = 11/234 (4%)
Query: 30 GRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFI 88
G + ++ G I SPG+P YP NC W + +PN I L F F +E H +C D++
Sbjct: 933 GEILTESTGTIQSPGHPNVYPHGINCTWHILV-QPNHLIHLMFET-FHLEFHYNCTNDYL 990
Query: 89 EIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSED 148
E+ D DSE++ LG++CG PP++ SSG+ L + F +D GF + YE +
Sbjct: 991 EVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINYEAISAATA- 1047
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C +++T GT SP FP YP+N +C + I + I + F F LE G+
Sbjct: 1048 CLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLIAVHFTNFSLEE-----AIGNY 1102
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
D+L+I DG PL+G + G+ P + S + L L F +D + GFSA
Sbjct: 1103 YTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSA 1156
Score = 129 bits (323), Expect = 9e-30
Identities = 78/239 (32%), Positives = 124/239 (51%), Gaps = 13/239 (5%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG + D+G ITSP YP Y S +C ++ AP+ I L F+ F+IE H C +D
Sbjct: 2689 CGG-IQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQ-GHTITLTFSD-FDIEPHTTCAWD 2745
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
+ +R+G S + ++G++CGN P TI S + L + F SD++ QG GF Y + T +
Sbjct: 2746 SVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGF---YATWNTQT 2802
Query: 147 EDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEG 206
C F S NGTI SP +P+ +P N C++T + + + F + + G+G
Sbjct: 2803 LGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLEISF----DNNFLIPSGDG 2858
Query: 207 DCKYDWLDIWDGIPHVG-PLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C+ ++ +W G V L+ CG P + + + + F + A A+ GFSA +
Sbjct: 2859 QCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEAPAQ-GFSASF 2916
Score = 128 bits (322), Expect = 1e-29
Identities = 82/240 (34%), Positives = 117/240 (48%), Gaps = 20/240 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEI-EKHDCKYD 86
CG L + G I SP +P YP + C W ++ P+ +Q I+LNF FEI C+ D
Sbjct: 817 CGDELTGE--GVIRSPFFPNVYPGERTCRWTIHQPQ-SQVILLNFTV-FEIGSSAHCETD 872
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
++EI + K+CG P I S + LY+ F + + GF ++ +
Sbjct: 873 YVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAKFS-----A 927
Query: 147 ED--CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
ED C + T GTI+SPG P YPH ++CT+ IL +P I L F F LE
Sbjct: 928 EDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHLMFETFHLEF------ 981
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
+C D+L+++D +G+YCG P L SS L L F TD +A +GF Y
Sbjct: 982 HYNCTNDYLEVYDTDSETS--LGRYCGKSIPPSLTSSGNSLMLVFVTDSDLAYEGFLINY 1039
Score = 126 bits (316), Expect = 6e-29
Identities = 79/231 (34%), Positives = 118/231 (51%), Gaps = 13/231 (5%)
Query: 36 DAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKY--DFIEIRDG 93
D G TSP +P +YP++ C + + Q I ++F +F +E+ Y DF+EIRDG
Sbjct: 1055 DLGTFTSPNFPNNYPNNWECIYRITV-RTGQLIAVHFT-NFSLEEAIGNYYTDFLEIRDG 1112
Query: 94 DSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNF 153
E + LLG G+ PPTIIS + L++KF SD +GFS ++ TG C N
Sbjct: 1113 GYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQIDTRSGFSAYWDGSSTG---CGGNL 1169
Query: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
T+ +GT SP +P Y H+ +C + + + L+F F LEH P +C D+L
Sbjct: 1170 TTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKDFHLEHHP------NCTLDYL 1223
Query: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
++DG L+ + CG + P +RSS + + TD GF A Y
Sbjct: 1224 AVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEY 1274
Score = 121 bits (304), Expect = 1e-27
Identities = 84/243 (34%), Positives = 123/243 (50%), Gaps = 20/243 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG + G SPGYP YP + C W + + P ++ L+F + DC DF
Sbjct: 1738 CGGTFYMAE-GIFNSPGYPDIYPPNVECVWNIVS-SPGNRLQLSFISFQLEDSQDCSRDF 1795
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISS-GSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
+EIR+G++ + L+G++CGN P S G L+++F SD + G GF + K
Sbjct: 1796 VEIREGNA-TGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSGSGTGFQATF--MKIFG 1852
Query: 147 EDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEG 206
D N +G + SP +PE YPHN + +T+ + + L D+E
Sbjct: 1853 ND---NIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMDIEEIQ------ 1903
Query: 207 DCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFH--TDMAVAKDGFSARY 264
+C YD L I+DG LIG YCGT+T E SSTG SLTFH +D +++ GF +
Sbjct: 1904 NCYYDKLRIYDGPSIHARLIGAYCGTQT--ESFSSTG-NSLTFHFYSDSSISGKGFLLEW 1960
Query: 265 YLV 267
+ V
Sbjct: 1961 FAV 1963
Score = 118 bits (296), Expect = 1e-26
Identities = 78/248 (31%), Positives = 124/248 (50%), Gaps = 26/248 (10%)
Query: 28 CGGRLNSKDAG-YITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKY 85
CGG L + DA ++ SPG+P Y + +C W++ AP+ ++ + +IE H C Y
Sbjct: 1978 CGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQAPDSTVELNIL---SLDIESHRTCAY 2034
Query: 86 DFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTG 145
D + IRDGD+ A L CG P I S+G ++I+FTSD + AGF+ +
Sbjct: 2035 DSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFH----- 2089
Query: 146 SEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGE 205
+ C + G I SP +PE YP NL+C++ +L + + I + F P Q+
Sbjct: 2090 -KSCGGYLHADRGIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHF------EQPFQIPN 2142
Query: 206 GDC---KYDWLDIWDG----IPHVGPL--IGKYCGTKTPSELRSSTGILSLTFHTDMAVA 256
GD + D+L + +G P +GP G +CG+ S L +S + + F +D +
Sbjct: 2143 GDSSCNQGDYLVLRNGPDICSPPLGPPGGNGHFCGSHASSTLFTSDNQMFVQFISDHSNE 2202
Query: 257 KDGFSARY 264
GF +Y
Sbjct: 2203 GQGFKIKY 2210
Score = 118 bits (296), Expect = 1e-26
Identities = 73/243 (30%), Positives = 119/243 (48%), Gaps = 8/243 (3%)
Query: 28 CGGRLNSKDAGYITSPGYPQ-DYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYD 86
CGG N +G ITSP Y DYP+ +C + + + ++ I L F+ + C +D
Sbjct: 3037 CGGVFNFS-SGIITSPAYSYADYPNDMHCLYTITVSD-DKVIELKFSDFDVVPSTSCSHD 3094
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
++ I DG + S LLGK CG+ PP + SS + + + F +D + G+ + +
Sbjct: 3095 YLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQTLGPQ 3154
Query: 147 EDCSKNFTSPNGTIESPGFPEK--YPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
+ C T N T SP Y NL+C + I+A I L F F LE +
Sbjct: 3155 QGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHLTFNTFALEAASTR-- 3212
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD++ ++DG L G +CG+ P+ SS L++ F +D+ + ++GF+A Y
Sbjct: 3213 -QRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNATY 3271
Query: 265 YLV 267
++
Sbjct: 3272 TIM 3274
Score = 117 bits (294), Expect = 2e-26
Identities = 67/227 (29%), Positives = 113/227 (49%), Gaps = 11/227 (4%)
Query: 35 KDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGD 94
K G + SPG+P +Y + ++C + AP+ N I L F+ +C+ DF+E+R+G
Sbjct: 3401 KAFGNLRSPGWPDNYDNDKDCTVTLTAPQ-NHTISLFFHSLGIENSVECRNDFLEVRNGS 3459
Query: 95 SESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFT 154
+ ++ LLGK+CG + P + S + LY++F SD G+ + I+ + C
Sbjct: 3460 NSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGYEI---IWTSSPSGCGGTLY 3516
Query: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLD 214
G+ SPG+P YP+N C + ++A + + F ++ DP GDC ++L
Sbjct: 3517 GDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVTINFYFISID-DP-----GDCVQNYLT 3570
Query: 215 IWDGIPHVGPLIGKYCGTKTP-SELRSSTGILSLTFHTDMAVAKDGF 260
++DG P G YCG T + +S+ + + FH D A F
Sbjct: 3571 LYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADYARRPSAF 3617
Score = 112 bits (279), Expect = 1e-24
Identities = 81/265 (30%), Positives = 117/265 (44%), Gaps = 26/265 (9%)
Query: 12 ALYF---SRHQVRGQ--------PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVY 60
ALYF S H G+ P CGG L G I SPGYP +YP ++C WIV
Sbjct: 563 ALYFHLYSEHLRNGRGFTVRWETQQPECGGILTGP-YGSIKSPGYPGNYPPGRDCVWIV- 620
Query: 61 APEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSM 119
P+ + F +E H DC D++EIRDG LLGK C + P + ++G
Sbjct: 621 VTSPDLLVTFTFGT-LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPF 679
Query: 120 LYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTI 179
I F SD GF + Y + C N+T P G + P + H C + +
Sbjct: 680 ARIHFHSDSQISDQGFHITY-LTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMM 738
Query: 180 LAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELR 239
+I + F +L+ + D +++++ DG L+GK CG T S ++
Sbjct: 739 KQPQGEQIQINFTHVELQ------CQSDSSQNYIEVRDG----ETLLGKVCGNGTISHIK 788
Query: 240 SSTGILSLTFHTDMAVAKDGFSARY 264
S T + + F D +V K F A Y
Sbjct: 789 SITNSVWIRFKIDASVEKASFRAVY 813
Score = 111 bits (278), Expect = 2e-24
Identities = 75/255 (29%), Positives = 122/255 (47%), Gaps = 15/255 (5%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD--CKY 85
CGG +S D G I SP +PQ++P + C W + ++ + ++F+ +F I D C+
Sbjct: 2805 CGGIFHS-DNGTIRSPHWPQNFPENSRCSWTAITHK-SKHLEISFDNNFLIPSGDGQCQN 2862
Query: 86 DFIEIRDGDSE-SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKT 144
F+++ G E LL CGN+AP +I+ + F S A GFS +
Sbjct: 2863 SFVKVWAGTEEVDKALLATGCGNVAPGPVITPSNTFTAVFQSQEA-PAQGFSASFV---- 2917
Query: 145 GSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
C NFT P+G I SP +P++Y +N++CT+ I A P ++L F+ F LE
Sbjct: 2918 --SRCGSNFTGPSGYIISPNYPKQYDNNMNCTYVIEANPLSVVLLTFVSFHLE--ARSAV 2973
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
G C D + I G + CG + P+ L + G + L F+++ + GF Y
Sbjct: 2974 TGSCVNDGVHIIRGYSVMSTPFATVCGDEMPAPL-TIAGPVLLNFYSNEQITDFGFKFSY 3032
Query: 265 YLVHQEPLENFQCNV 279
++ + NF +
Sbjct: 3033 RIISCGGVFNFSSGI 3047
Score = 111 bits (277), Expect = 2e-24
Identities = 76/244 (31%), Positives = 116/244 (47%), Gaps = 25/244 (10%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYD 86
CGG L + +I SP YP Y C W + + L F F +E H +C D
Sbjct: 1165 CGGNLTTSSGTFI-SPNYPMPYYHSSECYWWLKSSH-GSAFELEFKD-FHLEHHPNCTLD 1221
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
++ + DG S ++ LL + CG+ PP I SSG ++IK +D +QG GF Y
Sbjct: 1222 YLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQGRGFKAEYR------ 1275
Query: 147 EDCSKNFTSPN---GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQV 203
+ C +N N G +ES G+P Y N C +TI A + FL FDLEH
Sbjct: 1276 QTC-ENVVIVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFDLEH----- 1329
Query: 204 GEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTD-MAVAKDGFSA 262
+C D+L+++DG +G+YCG P +++ L + TD + + GF
Sbjct: 1330 -HINCSTDYLELYDGPRQ----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQM 1384
Query: 263 RYYL 266
++++
Sbjct: 1385 QWFV 1388
Score = 109 bits (272), Expect = 8e-24
Identities = 71/244 (29%), Positives = 115/244 (47%), Gaps = 16/244 (6%)
Query: 25 DPPCGGRLNSKDAGYITSPGYP--QDYPSHQNCEWIVYAP-EPNQKIVLNFNPHFEIEKH 81
D CGG L + G TSPGY ++Y + NCEW + P + N I ++F +
Sbjct: 2567 DAVCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQ 2626
Query: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPT-IISSGSMLYIKFTSDYARQGAGFSLRYE 140
DC++D +E R GD++ L+ + CG P ++ S ++I F ++ + GF +Y
Sbjct: 2627 DCQFDVLEFRVGDADGP-LMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYS 2685
Query: 141 IFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDP 200
DC +G I SP +P Y C+ + A I L F FD+E
Sbjct: 2686 F-----TDCGGIQIGDSGVITSPNYPNAYDSLTHCSSLLEAPQGHTITLTFSDFDIE--- 2737
Query: 201 LQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGF 260
C +D + + +G P+IG+YCG P ++S + L +TF++D ++ GF
Sbjct: 2738 ---PHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFNSDHSLQGGGF 2794
Query: 261 SARY 264
A +
Sbjct: 2795 YATW 2798
Score = 108 bits (270), Expect = 1e-23
Identities = 67/236 (28%), Positives = 117/236 (49%), Gaps = 24/236 (10%)
Query: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFN-PHFEIEKH-DCKYDFIEIRDGDS 95
G + S GYP Y +Q+C W + A N +N+ F++E H +C D++E+ DG
Sbjct: 1289 GILESIGYPNPYSENQHCNWTIRATTGN---TVNYTFLAFDLEHHINCSTDYLELYDGPR 1345
Query: 96 ESADLLGKHCG-NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFT 154
+ +G++CG ++ PP +S + + T R+ GF +++ ++ G E +
Sbjct: 1346 Q----MGRYCGVDLPPPGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGE-----LS 1396
Query: 155 SPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLD 214
G+ SPGFP +YP N +C + I P I L FD+E+ C +D L+
Sbjct: 1397 GATGSFSSPGFPNRYPPNKECIWYIRTDPGSSIQLTIHDFDVEY------HSRCNFDVLE 1450
Query: 215 IWDGIPHVGPLIGKYCGTKTPS---ELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
I+ G P I + C ++P ++ S+ L++ F TD+++ GF+A + V
Sbjct: 1451 IYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAV 1506
Score = 102 bits (253), Expect = 1e-21
Identities = 65/239 (27%), Positives = 112/239 (46%), Gaps = 16/239 (6%)
Query: 25 DPPCGGRLNSK-DAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDC 83
D PCGG N+ I+SP C W++ +P P+Q++ + ++ DC
Sbjct: 3275 DMPCGGTYNATWTPQNISSPNSSDPDVPFSICTWVIDSP-PHQQVKITVWA-LQLTSQDC 3332
Query: 84 KYDFIEIRDGDSESADLLGKHCGNIAP--PTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
++++++D + + CG A P SS S + F S + + S Y+I
Sbjct: 3333 TQNYLQLQDSPQGHGNSRFQFCGRNASAVPVFYSSMSTAMVIFKSGVVNRNSRMSFTYQI 3392
Query: 142 FKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPL 201
DC++++ G + SPG+P+ Y ++ DCT T+ A I L F +E+
Sbjct: 3393 -----ADCNRDYHKAFGNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSV- 3446
Query: 202 QVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGF 260
+C+ D+L++ +G PL+GKYCGT P+ + S L L F +D + G+
Sbjct: 3447 -----ECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFKSDSVTSDRGY 3500
Score = 100 bits (249), Expect = 3e-21
Identities = 68/239 (28%), Positives = 114/239 (47%), Gaps = 14/239 (5%)
Query: 28 CGGRLNSKDAGYITSPGYPQ-DYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYD 86
CGGR+ + +G + S G+P Y + CEW + + + ++F C+ D
Sbjct: 2336 CGGRVPGQ-SGVVESIGHPTLPYRDNLFCEWHLQGLSGHY-LTISFEDFNLQNSSGCEKD 2393
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGS 146
F+EI D + S ++LG++CGN P +I +S + ++F +D + +GF LR+E +
Sbjct: 2394 FVEIWDNHT-SGNILGRYCGNTIPDSIDTSSNTAVVRFVTDGSVTASGFRLRFE---SSM 2449
Query: 147 EDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEG 206
E+C + GT SP +P PH C + I A I L F L P
Sbjct: 2450 EECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRITLMFNNLRLATHP------ 2503
Query: 207 DCKYDWLDIWDGIPHVGPLIGKYCGT-KTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C + + +++GI P + K C + +E++SS + + F TD + GF+A Y
Sbjct: 2504 SCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDGSRPYGGFTASY 2562
Score = 99.0 bits (245), Expect = 1e-20
Identities = 68/242 (28%), Positives = 113/242 (46%), Gaps = 21/242 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHD-CKYD 86
CGG L+ G +SPG+P YP ++ C W + +P I L + F++E H C +D
Sbjct: 1391 CGGELSGA-TGSFSSPGFPNRYPPNKECIWYIRT-DPGSSIQLTIHD-FDVEYHSRCNFD 1447
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPT---IISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
+EI G + + + C +P + S+G+ L I+F +D + G GF+ ++
Sbjct: 1448 VLEIYGGPDFHSPRIAQLCTQRSPENPMQVSSTGNELAIRFKTDLSINGRGFNASWQAVT 1507
Query: 144 TGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQV 203
G C F +P+G I SP +P Y N DC++ I ++L F FDLE
Sbjct: 1508 GG---CGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVLLNFTDFDLE------ 1558
Query: 204 GEGDCKYDWLDIWDGIPHVGPLIGKYCG-TKTPSELRSSTGILSLTFHTDMAVAKDGFSA 262
+ C + +DG+ + + CG + + + SS L L F + + GF A
Sbjct: 1559 PQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGPSRQNRGFRA 1614
Query: 263 RY 264
++
Sbjct: 1615 QF 1616
Score = 95.9 bits (237), Expect = 9e-20
Identities = 70/241 (29%), Positives = 113/241 (46%), Gaps = 25/241 (10%)
Query: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEK-HDCKYDFIEIRDGDSE 96
G + SP +P++YP + N +W V + +V +IE+ +C YD + I DG S
Sbjct: 1861 GKVASPFWPENYPHNSNYQWTVNVNASH--VVHGRILEMDIEEIQNCYYDKLRIYDGPSI 1918
Query: 97 SADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNFTSP 156
A L+G +CG + S+G+ L F SD + G GF L + F + D +P
Sbjct: 1919 HARLIGAYCGT-QTESFSSTGNSLTFHFYSDSSISGKGFLLEW--FAVDAPDGVLPTIAP 1975
Query: 157 NGT------------IESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
+ SPG+P+ Y + +DCT+ I A P + L L D+E
Sbjct: 1976 GACGGFLRTGDAPVFLFSPGWPDSYSNRVDCTWLIQA-PDSTVELNILSLDIE------S 2028
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
C YD L I DG ++ + CG + P +RS+ + + F +D +V + GF+A +
Sbjct: 2029 HRTCAYDSLVIRDGDNNLAQQLAVLCGREIPGPIRSTGEYMFIRFTSDSSVTRAGFNASF 2088
Query: 265 Y 265
+
Sbjct: 2089 H 2089
Score = 91.7 bits (226), Expect = 2e-18
Identities = 70/241 (29%), Positives = 109/241 (45%), Gaps = 21/241 (8%)
Query: 25 DPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHDC 83
D CGG + G + P + + C +++ P+ Q I +NF H E++ + D
Sbjct: 705 DLRCGGNYTDPE-GELFLPELSGPFTHTRQCVYMMKQPQGEQ-IQINFT-HVELQCQSDS 761
Query: 84 KYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
++IE+RDG++ LLGK CGN I S + ++I+F D + + A F Y++
Sbjct: 762 SQNYIEVRDGET----LLGKVCGNGTISHIKSITNSVWIRFKIDASVEKASFRAVYQV-- 815
Query: 144 TGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQV 203
C T G I SP FP YP C +TI I+L F +F++
Sbjct: 816 ----ACGDELTG-EGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIG------ 864
Query: 204 GEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSAR 263
C+ D+++I P KYCGT PS + S L +TF + GF A+
Sbjct: 865 SSAHCETDYVEIGSSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVKSSSTENHGFMAK 924
Query: 264 Y 264
+
Sbjct: 925 F 925
Score = 89.0 bits (219), Expect = 1e-17
Identities = 72/248 (29%), Positives = 113/248 (45%), Gaps = 34/248 (13%)
Query: 24 PDPPCGGRLNSKDAGYITSPGYPQD--YPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-- 79
P CGG L + + SP + Y + NC WI+ AP N+ I L FN F +E
Sbjct: 3153 PQQGCGGYLTGSNNTF-ASPDSDSNGMYDKNLNCVWIIIAPV-NKVIHLTFNT-FALEAA 3209
Query: 80 --KHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSL 137
+ C YD++++ DGDSE+A+L G CG+ P ISSG+ L ++F SD + GF+
Sbjct: 3210 STRQRCLYDYVKLYDGDSENANLAGTFCGSTVPAPFISSGNFLTVQFISDLTLEREGFNA 3269
Query: 138 RYEIFKT---GSEDCS---KNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQF 191
Y I G+ + + +N +SPN + P P CT+ I + P ++ +
Sbjct: 3270 TYTIMDMPCGGTYNATWTPQNISSPNSS--DPDVPFSI-----CTWVIDSPPHQQVKITV 3322
Query: 192 LIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHT 251
LQ+ DC ++L + D G ++CG S+ + + T
Sbjct: 3323 W-------ALQLTSQDCTQNYLQLQDSPQGHGNSRFQFCGRNA-----SAVPVFYSSMST 3370
Query: 252 DMAVAKDG 259
M + K G
Sbjct: 3371 AMVIFKSG 3378
Score = 77.4 bits (189), Expect = 3e-14
Identities = 42/116 (36%), Positives = 68/116 (58%), Gaps = 7/116 (6%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG L D G TSPGYP YP++ CEW++ AP + + +NF + DC ++
Sbjct: 3511 CGGTLYG-DRGSFTSPGYPGTYPNNTYCEWVLVAPA-GRLVTINFYFISIDDPGDCVQNY 3568
Query: 88 IEIRDGDSESADLLGKHCG---NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYE 140
+ + DG + S+ G +CG +IAP ++S + ++IKF +DYAR+ + F L ++
Sbjct: 3569 LTLYDGPNASSPSSGPYCGGDTSIAP--FVASSNQVFIKFHADYARRPSAFRLTWD 3622
>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
Length = 449
Score = 140 bits (354), Expect = 2e-33
Identities = 86/268 (32%), Positives = 133/268 (49%), Gaps = 17/268 (6%)
Query: 5 PLTWVFLALYFSRHQVRGQPDPP--CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAP 62
PL L F++ Q P CGG + ++GY+ S G+P YP ++ C W + P
Sbjct: 12 PLLTACALLPFAQGQTPNYTRPVFLCGGDVKG-ESGYVASEGFPNLYPPNKECIWTITVP 70
Query: 63 EPNQKIVLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLY 121
E Q + L+F F++E H C+YD +E+ G S LG+ CG P +++ G+ +
Sbjct: 71 E-GQTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVT 128
Query: 122 IKFTSDYARQGAGFSLRYEIFKTGSED---CSKNFTSPNGTIESPGFPEK-YPHNLDCTF 177
++ T+D G GF L Y T + C GT+ +P +PE YP + C++
Sbjct: 129 LRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSW 188
Query: 178 TILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDG-IPHVGPLIGKYCGTKTPS 236
I+A P I L F FDLE D C+YD + +++G + +GK+CG P
Sbjct: 189 HIIAPPDQVIALTFEKFDLEPDTY------CRYDSVSVFNGAVSDDSRRLGKFCGDAVPG 242
Query: 237 ELRSSTGILSLTFHTDMAVAKDGFSARY 264
+ S L + F +D++V DGFSA Y
Sbjct: 243 SISSEGNELLVQFVSDLSVTADGFSASY 270
Score = 82.0 bits (201), Expect = 1e-15
Identities = 54/159 (33%), Positives = 80/159 (50%), Gaps = 6/159 (3%)
Query: 13 LYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQ-DYPSHQNCEWIVYAPEPNQKIVLN 71
L++S G CGGRL K G +T+P +P+ DYP +C W + AP P+Q I L
Sbjct: 144 LWYSGRATSGTEHQFCGGRLE-KAQGTLTTPNWPESDYPPGISCSWHIIAP-PDQVIALT 201
Query: 72 FNPHFEIEKHD-CKYDFIEIRDGD-SESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA 129
F F++E C+YD + + +G S+ + LGK CG+ P +I S G+ L ++F SD +
Sbjct: 202 FEK-FDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAVPGSISSEGNELLVQFVSDLS 260
Query: 130 RQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEK 168
GFS Y+ G+ + GT P K
Sbjct: 261 VTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPK 299
>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
Length = 449
Score = 137 bits (344), Expect = 3e-32
Identities = 82/240 (34%), Positives = 123/240 (51%), Gaps = 17/240 (7%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEP-NQKIVLNFNPHFEIE-KHDCKY 85
CGG L +G +TSP YP +YP+ C W++ A P + K+V F++E +C Y
Sbjct: 145 CGGVLTGL-SGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVF---VDFQVEGNEECTY 200
Query: 86 DFIEIRDGDSESADLLGKH-CGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKT 144
D++ + G + G H CG+ PPT++S G L + F SD+ G GF Y
Sbjct: 201 DYVAVLGGPGPTR---GHHYCGSTRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYF---- 253
Query: 145 GSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
S +C + + + G SP +P YP+N+ C +TI P ++ + FL DLE +P +
Sbjct: 254 -SGECQEVYMAMRGNFSSPQYPSSYPNNIRCHWTIRLPPGYQVKVFFLDLDLE-EPNSLT 311
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
+ C +D L +DG PL+G +CG P + SS L L HTD + + GFS Y
Sbjct: 312 K-TCDFDHLAAFDGASEEAPLLGNWCGHHLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAY 370
Score = 126 bits (317), Expect = 5e-29
Identities = 80/250 (32%), Positives = 125/250 (50%), Gaps = 20/250 (8%)
Query: 19 QVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEI 78
Q + CGG L S +G +SP +P+ YP + C W++ E ++L F+ F++
Sbjct: 21 QAQAMEGVKCGGVL-SAPSGNFSSPNFPRLYPYNTECSWLIVVAE-GSSVLLTFHA-FDL 77
Query: 79 EKHD-CKYDFIEIRDGDS-ESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFS 136
E HD C +DF+EI +G S + +LLG+ CG + PP SS ++ + F SD GFS
Sbjct: 78 EYHDTCSFDFLEIYNGASPDKGNLLGRFCGKVPPPPFTSSWHVMSVIFHSDKHVASHGFS 137
Query: 137 LRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDL 196
Y+ + C T +G + SP +P YP++++C + I A + L F+ F +
Sbjct: 138 AGYQ-----KDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVDFQV 192
Query: 197 EHDPLQVGEGDCKYDWLDIWDGIPHVGPLIG-KYCGTKTPSELRSSTGILSLTFHTDMAV 255
E G +C YD++ + G GP G YCG+ P L S L + F +D +
Sbjct: 193 E------GNEECTYDYVAVLGG---PGPTRGHHYCGSTRPPTLVSLGHELQVVFKSDFNI 243
Query: 256 AKDGFSARYY 265
GF A Y+
Sbjct: 244 GGRGFKAYYF 253
>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
Length = 2351
Score = 134 bits (336), Expect = 3e-31
Identities = 96/271 (35%), Positives = 140/271 (51%), Gaps = 30/271 (11%)
Query: 276 QCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLH--GDDNGWTPNLDSNKE---YLQ 330
+C PLGM SG I + QI+AS Y G+W P+ +RLH G N W S KE +++
Sbjct: 2039 KCQTPLGMASGHIRDFQITASGQY--GQWAPKLARLHYSGSINAW-----STKEPFSWIK 2091
Query: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK--VFQANN 388
VDL ++ I TQGA R+ + Y+ + + S +G+ W YR VF N
Sbjct: 2092 VDLLAPMIIHGIKTQGA--RQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGNV 2149
Query: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448
D++ + N + P++ R++R+ P + LR+EL GC + CS LGM S I+D+
Sbjct: 2150 DSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGMESKAISDA 2207
Query: 449 QISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKTVKGVIIQ 504
QI+ASS WSPS ARL + RS + PQ +EWLQVD V GV Q
Sbjct: 2208 QITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMKVTGVTTQ 2265
Query: 505 GARGGDSITAVEARAFVRKFKVSYSLNGKDW 535
G + ++ +V++F +S S +G W
Sbjct: 2266 G------VKSLLTSMYVKEFLISSSQDGHQW 2290
Score = 128 bits (321), Expect = 2e-29
Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)
Query: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332
C++PLGMES I++ QI+ASS +++ W+P ++RLH G N W P +++ KE+LQVD
Sbjct: 2193 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 2252
Query: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392
+ +T + TQG S T YVK + + S +G W ++ KVFQ N D+
Sbjct: 2253 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 2310
Query: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431
V+N L PLLTR++RI PQ+W IALR+E+ GC D
Sbjct: 2311 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 2349
Score = 57.8 bits (138), Expect = 3e-08
Identities = 40/105 (38%), Positives = 54/105 (51%), Gaps = 14/105 (13%)
Query: 434 CSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVSSRS--GWFPRIPQAQPGEEWLQVD 491
C LGM SG I D QI+AS Q W+P ARL S S W + P + W++VD
Sbjct: 2040 CQTPLGMASGHIRDFQITASG-QYGQWAPKLARLHYSGSINAWSTKEPFS-----WIKVD 2093
Query: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE 536
L P + G+ QGAR S ++ +F + YSL+GK W+
Sbjct: 2094 LLAPMIIHGIKTQGARQKFS------SLYISQFIIMYSLDGKKWQ 2132
>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
Length = 415
Score = 131 bits (329), Expect = 2e-30
Identities = 80/259 (30%), Positives = 136/259 (52%), Gaps = 16/259 (6%)
Query: 12 ALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLN 71
A SR Q +P CGG L ++G+I S G+P YP + C W + PE + +VLN
Sbjct: 17 ATQLSRQQSPERPVFTCGGILTG-ESGFIGSEGFPGVYPPNSKCTWKITVPE-GKVVVLN 74
Query: 72 FNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYAR 130
F ++E + C+YDF+++ +G + + +G+ CG P ++SSG+ + ++ SD
Sbjct: 75 FR-FIDLESDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGALVSSGNKMMVQMISDANT 132
Query: 131 QGAGFSLRY---EIFKTGSEDCSKNFTSPNGTIESPGFPEK-YPHNLDCTFTILAKPKME 186
G GF + E + G + C P+G+ ++P +P++ YP + C + I+A
Sbjct: 133 AGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQL 192
Query: 187 IILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIP-HVGPLIGKYCGTKTPSELRSSTGIL 245
I L+F FD+E D C+YD++ +++G + IGKYCG P+ + S L
Sbjct: 193 IELKFEKFDVERDNY------CRYDYVAVFNGGEVNDARRIGKYCGDSPPAPIVSERNEL 246
Query: 246 SLTFHTDMAVAKDGFSARY 264
+ F +D+++ DGF Y
Sbjct: 247 LIQFLSDLSLTADGFIGHY 265
Score = 71.6 bits (174), Expect = 2e-12
Identities = 45/138 (32%), Positives = 64/138 (46%), Gaps = 7/138 (5%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C T +G I S GFP YP N CT+ I ++L F DLE D L C
Sbjct: 33 CGGILTGESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNL------C 86
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVH 268
+YD++D+++G + G IG++CGT P L SS + + +D A +GF A +
Sbjct: 87 RYDFVDVYNGHAN-GQRIGRFCGTFRPGALVSSGNKMMVQMISDANTAGNGFMAMFSAAE 145
Query: 269 QEPLENFQCNVPLGMESG 286
+ C L SG
Sbjct: 146 PNERGDQYCGGLLDRPSG 163
>gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
Length = 216
Score = 128 bits (321), Expect = 2e-29
Identities = 67/159 (42%), Positives = 97/159 (61%), Gaps = 6/159 (3%)
Query: 277 CNVPLGMESGRIANEQISASSTYSD--GRWTPQQSRLH--GDDNGWTPNLDSNKEYLQVD 332
C++PLGMES I++ QI+ASS +++ W+P ++RLH G N W P +++ KE+LQVD
Sbjct: 58 CSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEWLQVD 117
Query: 333 LRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATE 392
+ +T + TQG S T YVK + + S +G W ++ KVFQ N D+
Sbjct: 118 FQKTMKVTGVTTQGVKSLLTS--MYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFT 175
Query: 393 VVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTD 431
V+N L PLLTR++RI PQ+W IALR+E+ GC D
Sbjct: 176 PVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQD 214
Score = 84.0 bits (206), Expect = 3e-16
Identities = 57/158 (36%), Positives = 83/158 (52%), Gaps = 14/158 (8%)
Query: 382 KVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGML 441
KVF N D++ + N + P++ R++R+ P + LR+EL GC + CS LGM
Sbjct: 8 KVFFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDLNS--CSMPLGME 65
Query: 442 SGLIADSQISASS---TQEYLWSPSAARL-VSSRSGWFPRIPQAQPGEEWLQVDLGTPKT 497
S I+D+QI+ASS WSPS ARL + RS + PQ +EWLQVD
Sbjct: 66 SKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWR--PQVNNPKEWLQVDFQKTMK 123
Query: 498 VKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDW 535
V GV QG + ++ +V++F +S S +G W
Sbjct: 124 VTGVTTQG------VKSLLTSMYVKEFLISSSQDGHQW 155
>gi|54792129 discoidin, CUB and LCCL domain containing 2 [Homo
sapiens]
Length = 775
Score = 128 bits (321), Expect = 2e-29
Identities = 112/440 (25%), Positives = 190/440 (43%), Gaps = 62/440 (14%)
Query: 9 VFLALYFSRHQVRGQPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKI 68
+ L L Q CG + ++G +TS YPQ YP+ CEW + + +++
Sbjct: 53 LLLVLLLLLEDAGAQQGDGCGHTVLGPESGTLTSINYPQTYPNSTVCEWEIRV-KMGERV 111
Query: 69 VLNFNPHFEIEKHD-CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSD 127
+ F F+IE D C ++++ I +G S +GK+CG L ++
Sbjct: 112 RIKFGD-FDIEDSDSCHFNYLRIYNGIGVSRTEIGKYCG-------------LGLQMNHS 157
Query: 128 YARQGAGFSLRYEIFKTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEI 187
+G +L +F +G + F + +++++ K +
Sbjct: 158 IESKGNEITL---LFMSGIHVSGRGFLA--------------------SYSVIDKQDLIT 194
Query: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSST--GIL 245
L LE + + C + +I IPH C + + S+T G +
Sbjct: 195 CLDTASNFLEPEFSKYCPAGCLLPFAEISGTIPHGYRDSSPLCMAGVHAGVVSNTLGGQI 254
Query: 246 SLTF-----HTDMAVAKDGFSARYYLVHQEPLENFQ---CNVPLGMESGRIANEQISASS 297
S+ + + ++A + S +L L F+ C LGMESG IA+ QI+ASS
Sbjct: 255 SVVISKGIPYYESSLANNVTSVVGHL--STSLFTFKTSGCYGTLGMESGVIADPQITASS 312
Query: 298 -------TYSDGRWTPQQSRLHGDDNGWTPNLDSNKEYLQVDLRFLTMLTAIATQGAISR 350
T + W P+++RL W ++LQ+DL +T I T G S
Sbjct: 313 VLEWTDHTGQENSWKPKKARLKKPGPPWAAFATDEYQWLQIDLNKEKKITGIITTG--ST 370
Query: 351 ETQNGYYVKSYKLEVSTNGEDWMVYRHG--KNHKVFQANNDATEVVLNKLHAPLLTRFVR 408
++ YYV +Y++ S +G+ W VYR + K+FQ N D + V N P++ RF+R
Sbjct: 371 MVEHNYYVSAYRILYSDDGQKWTVYREPGVEQDKIFQGNKDYHQDVRNNFLPPIIARFIR 430
Query: 409 IRPQTWHSGIALRLELFGCR 428
+ P W IA+++EL GC+
Sbjct: 431 VNPTQWQQKIAMKMELLGCQ 450
Score = 68.9 bits (167), Expect = 1e-11
Identities = 43/123 (34%), Positives = 60/123 (48%), Gaps = 17/123 (13%)
Query: 434 CSNMLGMLSGLIADSQISASST--------QEYLWSPSAARLVSSRSGWFPRIPQAQPGE 485
C LGM SG+IAD QI+ASS QE W P ARL W A
Sbjct: 292 CYGTLGMESGVIADPQITASSVLEWTDHTGQENSWKPKKARLKKPGPPW---AAFATDEY 348
Query: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQ 545
+WLQ+DL K + G+I G+ T VE +V +++ YS +G+ W ++P +Q
Sbjct: 349 QWLQIDLNKEKKITGIITTGS------TMVEHNYYVSAYRILYSDDGQKWTVYREPGVEQ 402
Query: 546 PKV 548
K+
Sbjct: 403 DKI 405
>gi|24041026 neuropilin- and tolloid-like protein 2 precursor [Homo
sapiens]
Length = 525
Score = 125 bits (315), Expect = 8e-29
Identities = 73/237 (30%), Positives = 121/237 (51%), Gaps = 24/237 (10%)
Query: 24 PDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIE-KHD 82
P CG + + + G+ SP YP YP ++ C +I+ A P Q+I L F+ H+ IE +
Sbjct: 41 PATQCGIWVRTSNGGHFASPNYPDSYPPNKECIYILEAA-PRQRIELTFDEHYYIEPSFE 99
Query: 83 CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142
C++D +E+RDG + L+ ++CG +PP I S+G ++IKF+SD +G GF +Y
Sbjct: 100 CRFDHLEVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
Query: 143 KTGS-----------EDCSKNFTSPNGTIESPGFPE----KYPHNLDCTFTILAKPKMEI 187
DC + +G + S + K +DC +TI A PK +I
Sbjct: 160 PDPDFTYLGGILNPIPDCQFELSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKI 219
Query: 188 ILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGI 244
L+FL + +EH +CK +++ ++DG + L K+C T +++ TGI
Sbjct: 220 YLRFLDYQMEH------SNECKRNFVAVYDGSSSIENLKAKFCST-VANDVMLKTGI 269
Score = 69.3 bits (168), Expect = 9e-12
Identities = 38/114 (33%), Positives = 61/114 (53%), Gaps = 5/114 (4%)
Query: 154 TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWL 213
TS G SP +P+ YP N +C + + A P+ I L F EH ++ +C++D L
Sbjct: 51 TSNGGHFASPNYPDSYPPNKECIYILEAAPRQRIELTFD----EHYYIEPSF-ECRFDHL 105
Query: 214 DIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
++ DG PLI +YCG K+P +RS+ + + F +D + GF A+Y +
Sbjct: 106 EVRDGPFGFSPLIDRYCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFI 159
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 124 bits (310), Expect = 3e-28
Identities = 82/274 (29%), Positives = 142/274 (51%), Gaps = 29/274 (10%)
Query: 277 CNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLH--GDDNGWTPNL----DSNKEYLQ 330
C +P+G+ +G I++ QI AS G W P+ +RL+ G N W+ ++K ++Q
Sbjct: 1907 CRMPMGLSTGIISDSQIKASEFL--GYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQ 1964
Query: 331 VDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKV--FQANN 388
VD++ ++T I TQGA + Y + + S+N +W +++ V F N+
Sbjct: 1965 VDMQKEVIITGIQTQGA--KHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNS 2022
Query: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448
DA+ + N+ P++ R++RI P ++ LRLEL GC V CS LGM +G I +
Sbjct: 2023 DASTIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEVNG--CSTPLGMENGKIENK 2080
Query: 449 QISASSTQEY----LWSPSAARLVSSR--SGWFPRIPQAQPGEEWLQVDLGTPKTVKGVI 502
QI+ASS ++ W P ARL + + W + A ++WL++DL K + +I
Sbjct: 2081 QITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAK---ANNNKQWLEIDLLKIKKITAII 2137
Query: 503 IQGARGGDSITAVEARAFVRKFKVSYSLNGKDWE 536
QG + ++ + +V+ + + YS G +W+
Sbjct: 2138 TQGCK------SLSSEMYVKSYTIHYSEQGVEWK 2165
Score = 122 bits (305), Expect = 1e-27
Identities = 65/160 (40%), Positives = 100/160 (62%), Gaps = 9/160 (5%)
Query: 277 CNVPLGMESGRIANEQISASS---TYSDGRWTPQQSRLH--GDDNGWTPNLDSNKEYLQV 331
C+ PLGME+G+I N+QI+ASS ++ W P ++RL+ G N W ++NK++L++
Sbjct: 2066 CSTPLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVNAWQAKANNNKQWLEI 2125
Query: 332 DLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKN--HKVFQANND 389
DL + +TAI TQG S ++ YVKSY + S G +W YR + K+F+ N +
Sbjct: 2126 DLLKIKKITAIITQGCKSLSSE--MYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGNTN 2183
Query: 390 ATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
V N + P+++RF+R+ P+TW+ IALRLELFGC +
Sbjct: 2184 TKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDI 2223
Score = 50.4 bits (119), Expect = 4e-06
Identities = 34/119 (28%), Positives = 57/119 (47%), Gaps = 10/119 (8%)
Query: 429 VTDAPCSNMLGMLSGLIADSQISASSTQEYLWSPSAARLVS--SRSGW-FPRIPQAQPGE 485
+ D C +G+ +G+I+DSQI AS Y W P ARL + S + W ++ +
Sbjct: 1902 IMDRDCRMPMGLSTGIISDSQIKASEFLGY-WEPRLARLNNGGSYNAWSVEKLAAEFASK 1960
Query: 486 EWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
W+QVD+ + G+ QGA+ + +F V+YS N +W+ + T+
Sbjct: 1961 PWIQVDMQKEVIITGIQTQGAK------HYLKSCYTTEFYVAYSSNQINWQIFKGNSTR 2013
>gi|167830477 milk fat globule-EGF factor 8 protein isoform b [Homo
sapiens]
Length = 335
Score = 120 bits (301), Expect = 3e-27
Identities = 75/228 (32%), Positives = 123/228 (53%), Gaps = 18/228 (7%)
Query: 276 QCNVPLGMESGRIANEQISASSTYSD----GRWTPQQSRLH--GDDNGWTPNLDSNKEYL 329
+C PLG+E+G IAN QI+ASS W P+ +RL+ G N WTP+ + + ++
Sbjct: 69 KCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLNRAGMVNAWTPSSNDDNPWI 128
Query: 330 QVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDW-MVYRHGKNHKVFQANN 388
QV+L +T + TQGA + Y+K++K+ S NG ++ ++ K HK F N
Sbjct: 129 QVNLLRRMWVTGVVTQGASRLASHE--YLKAFKVAYSLNGHEFDFIHDVNKKHKEFVGNW 186
Query: 389 DATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRVTDAPCSNMLGMLSGLIADS 448
+ V +N P+ ++VR+ P + H+ LR EL GC + C+N LG+ + I D
Sbjct: 187 NKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCELNG--CANPLGLKNNSIPDK 244
Query: 449 QISASSTQE------YLWSPSAARLVSSRSGWFPRIPQAQPGEEWLQV 490
QI+ASS+ + + W+PS ARL + + + + ++WLQ+
Sbjct: 245 QITASSSYKTWGLHLFSWNPSYARL-DKQGNFNAWVAGSYGNDQWLQI 291
Score = 61.6 bits (148), Expect = 2e-09
Identities = 41/128 (32%), Positives = 67/128 (52%), Gaps = 14/128 (10%)
Query: 431 DAPCSNMLGMLSGLIADSQISASSTQEYL-----WSPSAARLVSSRSGWFPR-IPQAQPG 484
+ C LG+ +G IA+SQI+ASS + W P ARL +R+G P +
Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARL--NRAGMVNAWTPSSNDD 124
Query: 485 EEWLQVDLGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQ 544
W+QV+L V GV+ QGA + + + +++ FKV+YSLNG ++++I D +
Sbjct: 125 NPWIQVNLLRRMWVTGVVTQGA------SRLASHEYLKAFKVAYSLNGHEFDFIHDVNKK 178
Query: 545 QPKVGCSW 552
+ +W
Sbjct: 179 HKEFVGNW 186
Score = 52.8 bits (125), Expect = 8e-07
Identities = 45/152 (29%), Positives = 63/152 (41%), Gaps = 47/152 (30%)
Query: 277 CNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLDS-NKEYLQVDLRF 335
C PLG+++ I ++QI+ASS+Y W +L S N Y ++D
Sbjct: 230 CANPLGLKNNSIPDKQITASSSYKT----------------WGLHLFSWNPSYARLD--- 270
Query: 336 LTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHKVFQANNDATEVVL 395
QG N + SY + W+ ++F N D
Sbjct: 271 --------KQGNF-----NAWVAGSY------GNDQWL--------QIFPGNWDNHSHKK 303
Query: 396 NKLHAPLLTRFVRIRPQTWHSGIALRLELFGC 427
N P+L R+VRI P WH+ IALRLEL GC
Sbjct: 304 NLFETPILARYVRILPVAWHNRIALRLELLGC 335
>gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
precursor [Homo sapiens]
Length = 533
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 36 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 94
Query: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 95 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 154
Query: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
T D C G +ES ++ +DC + I A P+
Sbjct: 155 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 212
Query: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 213 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 265
Query: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
+ D F + + P E F C+ + + + + N
Sbjct: 266 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 312
>gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2
precursor [Homo sapiens]
Length = 532
Score = 113 bits (282), Expect = 5e-25
Identities = 81/287 (28%), Positives = 129/287 (44%), Gaps = 29/287 (10%)
Query: 23 QPDPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH- 81
Q CG + G TSP YP YP + C +I+ A P Q I L F+ + IE
Sbjct: 35 QKSVQCGTWTKHAEGGIFTSPNYPSKYPPDRECIYIIEAA-PRQCIELYFDEKYSIEPSW 93
Query: 82 DCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI 141
+CK+D IE+RDG + ++G+ CG PP I SSG L+IKF +D + GFS RY
Sbjct: 94 ECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNF 153
Query: 142 FKTGSED------------CSKNFTSPNGTIESPGFPEK----YPHNLDCTFTILAKPKM 185
T D C G +ES ++ +DC + I A P+
Sbjct: 154 --TPDPDFKDLGALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPRS 211
Query: 186 EIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGIL 245
+I L+FL +++++ +CK +++ ++DG V L K+C T +++ TG+
Sbjct: 212 KIYLRFLDYEMQN------SNECKRNFVAVYDGSSSVEDLKAKFCST-VANDVMLRTGLG 264
Query: 246 SLTFHTDMAVAKDGFSARYYLVHQEPLE--NFQCNVPLGMESGRIAN 290
+ D F + + P E F C+ + + + + N
Sbjct: 265 VIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCN 311
>gi|38045890 CUB and Sushi multiple domains 3 isoform 2 [Homo
sapiens]
Length = 3667
Score = 110 bits (274), Expect = 4e-24
Identities = 85/294 (28%), Positives = 129/294 (43%), Gaps = 72/294 (24%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG L +G TSP +P Y S+ C W++ A N+ I +NF F++E YD
Sbjct: 508 CGSNLQGP-SGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFE-EFDLE---IGYDT 562
Query: 88 IEIRDGDS--ESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA---------------- 129
+ I DG + +L G+ P I+S S +++ +D +
Sbjct: 563 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKE 622
Query: 130 ------------RQGAGFS----LRYEI---FKTGSED--------------------CS 150
R+G GFS LR+E F+ E C
Sbjct: 623 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCL 682
Query: 151 KNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKY 210
NFT+P GT+ SP +PE Y +NL+C +TI++ P I L F FDLE ++
Sbjct: 683 SNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----------SQF 732
Query: 211 DWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
D+L + DG P++G + G + PS L S++ IL L F D +++ GF+ Y
Sbjct: 733 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 786
Score = 109 bits (272), Expect = 8e-24
Identities = 86/322 (26%), Positives = 134/322 (41%), Gaps = 77/322 (23%)
Query: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSES 97
G + SP YP+ Y ++ NC W + + +P +I L+FN F++E ++DF+ ++DGDS
Sbjct: 690 GTVLSPDYPEGYGNNLNCIWTIIS-DPGSRIHLSFND-FDLES---QFDFLAVKDGDSPE 744
Query: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF--------------- 142
+ +LG G P + S+ +L ++F +D++ G GF++ Y F
Sbjct: 745 SPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINAR 804
Query: 143 ---------KTGSEDCSKNFTSPNGT---------------------------------- 159
+ S C + F GT
Sbjct: 805 RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSG 864
Query: 160 -IESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDG 218
I SPG+P Y +L+C + I A+P I + F F E YD L++ DG
Sbjct: 865 VILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----------LNYDVLEVHDG 914
Query: 219 IPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCN 278
+ PL+G Y GT+ P L SS+ + L F TD + + +GF Y V + + C
Sbjct: 915 PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV---TVNTYSCL 971
Query: 279 VPLGMESGRIANEQISASSTYS 300
P GR S ST S
Sbjct: 972 DPGIPVHGRRYGHDFSIGSTVS 993
Score = 106 bits (265), Expect = 5e-23
Identities = 92/333 (27%), Positives = 133/333 (39%), Gaps = 82/333 (24%)
Query: 27 PCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPN--QKIVLNFNPHFEIEKHDCK 84
PCGG L +K G I SPGYP+ Y ++ NC W + PE Q V++F +H+
Sbjct: 1898 PCGGIL-TKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF-----ATEHN-- 1949
Query: 85 YDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSL------- 137
+D ++ DG +A LG + G P + S+ + LY+ F SD + AGF L
Sbjct: 1950 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 2009
Query: 138 -----------------RYEIFKTGSEDCSK--------------------NFTSP---- 156
RY + S C + N+ P
Sbjct: 2010 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2069
Query: 157 ---------NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
+G I SPGFP YP +LDCT+TI + LQF+ F E
Sbjct: 2070 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE---------- 2119
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
+D+L++ G +IG+ G + PS L S+T SL FH+D + K GF Y
Sbjct: 2120 TIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY 2179
Query: 268 HQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
+ C P +G + + T S
Sbjct: 2180 QLQ-----SCPDPRPFRNGFVIGNDFTVGQTIS 2207
Score = 97.4 bits (241), Expect = 3e-20
Identities = 83/295 (28%), Positives = 120/295 (40%), Gaps = 73/295 (24%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGGR + +G I SPGYP Y ++ C W++ +P + L F F+ E +D
Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEV-DPGNIVSLQFLA-FDTE---ASHDI 1428
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIIS---------------SGSMLYIKFTSDYA--- 129
+ + DG E+ LL + G++ P I S S S I+F+S A
Sbjct: 1429 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1488
Query: 130 ----------RQG--------------AGFSLRYEIFKTGSE----------------DC 149
R G G+ L+ E T + C
Sbjct: 1489 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1548
Query: 150 SKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCK 209
N T +G I SP FP YPH+ DC +TI I L F+ F +E +
Sbjct: 1549 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---------- 1598
Query: 210 YDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
YD+L I+DG PLIG + +K P + SS+ + L F +D +V+ GF Y
Sbjct: 1599 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1653
Score = 90.1 bits (222), Expect = 5e-18
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 77/308 (25%)
Query: 27 PCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYD 86
PCGG S +G I SPG+P Y NCEW++ A EP I + F F+ E + YD
Sbjct: 854 PCGGHF-SAPSGVILSPGWPGYYKDSLNCEWVIEA-EPGHSIKITFE-RFQTELN---YD 907
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI----- 141
+E+ DG + + LLG + G P + SS + +Y+ FT+D +R GF + YE
Sbjct: 908 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 967
Query: 142 ------------------FKTGSED-----------------CSKN--FTSP-------- 156
F GS C KN ++ P
Sbjct: 968 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 1027
Query: 157 NGTIESP-------GFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCK 209
G + P G+PE YP++L+CT+T+ + F F LE
Sbjct: 1028 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED----------H 1077
Query: 210 YDWLDIWDGIPHVGPLIGKYCGTKTPSELRS---STGILSLTFHTDMAVAKDGFSARYYL 266
+D+L I + PL + G+ P + + L F +D +++ +GF+ +
Sbjct: 1078 HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1136
Query: 267 VHQEPLEN 274
+ EP E+
Sbjct: 1137 YNLEPCED 1144
Score = 75.9 bits (185), Expect = 9e-14
Identities = 41/116 (35%), Positives = 66/116 (56%), Gaps = 7/116 (6%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG + + + G I SPGYP +YP+ Q+C W+V P P I +NF + + + YDF
Sbjct: 2243 CGGNITAMN-GTIYSPGYPDEYPNFQDCFWLVRVP-PGNGIYINFT----VLQTEPIYDF 2296
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
I + DG +++ +G+ GN A ++ S+ + + IKF SD+ G F L Y ++
Sbjct: 2297 ITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQ 2351
Score = 75.5 bits (184), Expect = 1e-13
Identities = 44/132 (33%), Positives = 64/132 (48%), Gaps = 15/132 (11%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C NGTIESPGFP YP+ +CT+ I+A+ + I + F F LE +
Sbjct: 25 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE--------- 75
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVH 268
YD+L ++DG PH + G P + S+ + SL +D AV+ GF V+
Sbjct: 76 -YDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFK-----VY 129
Query: 269 QEPLENFQCNVP 280
E L++ C P
Sbjct: 130 YEELQSSSCGNP 141
Score = 72.8 bits (177), Expect = 8e-13
Identities = 69/297 (23%), Positives = 118/297 (39%), Gaps = 77/297 (25%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG + + G + SP YP +Y ++ C +Y+ + +N + H + D
Sbjct: 1201 CGASATNNE-GILLSPNYPLNYENNHEC---IYSIQVQAGKGINISAR---TFHLAQGDV 1253
Query: 88 IEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK-TG 145
++I DG ++ LLG G ++ T+ S+ + L+++F SD GF L Y F+ +
Sbjct: 1254 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1313
Query: 146 SED------------------------CSKNFTSPNGTI--------------------- 160
ED C+ +T ++
Sbjct: 1314 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1373
Query: 161 -------ESPG------FPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
ES G +P Y +NL C + I P + LQFL FD E
Sbjct: 1374 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE---------- 1423
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
+D L +WDG P L+ + G+ P + S+ I+++ F TD ++K GF+ ++
Sbjct: 1424 ASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1480
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/138 (31%), Positives = 69/138 (50%), Gaps = 8/138 (5%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG L + G I SPG+P YP+ NC W++ A E N +I + F F +E+ +YD+
Sbjct: 25 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERN-RIQIVFQS-FALEE---EYDY 78
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147
+ + DG + + G PP + S+ S+ ++ TSD+A GF + YE ++ S
Sbjct: 79 LSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSS- 137
Query: 148 DCSKNFTSPNGTIESPGF 165
C P G + F
Sbjct: 138 -CGNPGVPPKGVLYGTRF 154
Score = 70.1 bits (170), Expect = 5e-12
Identities = 83/345 (24%), Positives = 128/345 (37%), Gaps = 85/345 (24%)
Query: 23 QPDPP-----CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFE 77
QP PP CGG L +G+I SP +P YP ++C+W + + I L F F
Sbjct: 1538 QPSPPVCIAPCGGNLTGS-SGFILSPNFPHPYPHSRDCDWTITV-NADYVISLAFIS-FS 1594
Query: 78 IEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISS-----------GSMLYIKFTS 126
IE + YDF+ I DG ++ L+G + P I SS GS+ Y F
Sbjct: 1595 IEPN---YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHL 1651
Query: 127 DYARQ-------------GAGFSLRYEIFKTGSEDCSKNF-------------------- 153
+Y + G + Y++ T + C +
Sbjct: 1652 EYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGW 1711
Query: 154 ---------------TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE- 197
T GT+ SP +P+ Y +C ++I + + QF+ F
Sbjct: 1712 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1771
Query: 198 HDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAK 257
HD ++V +G + L + L G + G P SS +++ F + +
Sbjct: 1772 HDVVEVYDGPTQQSSL--------LSSLSGSHSGESLP---LSSGNQITIRFTSVGPITA 1820
Query: 258 DGFSARYYLVHQEPLENFQC-NVPLGMESGRIANEQISASSTYSD 301
GF Y V + + QC +VP RI NE SS D
Sbjct: 1821 KGFHFVYQAVPR--TSSTQCSSVPEPRFGRRIGNEFAVGSSVLFD 1863
Score = 69.7 bits (169), Expect = 7e-12
Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 12/121 (9%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C N T+ NGTI SPG+P++YP+ DC + + P I + F + L+ +P+
Sbjct: 2243 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV--LQTEPI------- 2293
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVH 268
YD++ +WDG P IG++ G + S++ + + FH+D + GF Y +
Sbjct: 2294 -YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAY 2350
Query: 269 Q 269
Q
Sbjct: 2351 Q 2351
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/113 (33%), Positives = 61/113 (53%), Gaps = 10/113 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG + +G I+SP +P +Y ++ +C W + A EP I L F F++E+ KYD+
Sbjct: 201 CGGTMRGS-SGIISSPSFPNEYHNNADCTWTIVA-EPGDTISLIFT-DFQMEE---KYDY 254
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYE 140
+EI + + L G + PP IIS+ + L + F +D + GFS Y+
Sbjct: 255 LEIEGSEPPTIWLSGMN----IPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQ 303
Score = 58.9 bits (141), Expect = 1e-08
Identities = 70/301 (23%), Positives = 113/301 (37%), Gaps = 79/301 (26%)
Query: 25 DPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCK 84
D CGG + +G I SPGYP+ YP+ NC W V + + NF+ F +E H
Sbjct: 1024 DALCGGDVRGP-SGTILSPGYPEFYPNSLNCTWTVDVTH-GKGVQFNFHT-FHLEDH--- 1077
Query: 85 YDFIEIRDGDSESADLLGKHCGNIAPPTI---ISSGSMLYIKFTSDYARQGAGFSLRYE- 140
+D++ I + S + L + G+ PPTI + ++F SD++ GF++ +
Sbjct: 1078 HDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1136
Query: 141 -----------------------IFKTGSEDCSKNF------------------------ 153
I T + CS +
Sbjct: 1137 YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1196
Query: 154 ---------TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
T+ G + SP +P Y +N +C ++I + I + F L
Sbjct: 1197 CVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-------A 1249
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPS-ELRSSTGILSLTFHTDMAVAKDGFSAR 263
+GD L I+DG L+G + G L S++ L L F++D +GF
Sbjct: 1250 QGDV----LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1305
Query: 264 Y 264
Y
Sbjct: 1306 Y 1306
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/152 (29%), Positives = 73/152 (48%), Gaps = 17/152 (11%)
Query: 17 RHQVRGQPDPPC-----GGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLN 71
R Q+ G P P C L G I SPGYP YP+ Q C W + + E I +
Sbjct: 2402 RLQMDGAP-PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSI-SVEKGYNITM- 2458
Query: 72 FNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPP-TIISSGSMLYIKFTSDYAR 130
F F+ EK ++D +++ DG + + +L G+ + I S+G +++++++D+
Sbjct: 2459 FVEFFQTEK---EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN 2515
Query: 131 QGAGFSLRYEIFKTGSEDCSKNFTSPNGTIES 162
GF +RY F CS + P+G I S
Sbjct: 2516 NKKGFRIRYIAFY-----CSTPESPPHGYIIS 2542
Score = 57.4 bits (137), Expect = 3e-08
Identities = 42/116 (36%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C +G I SP FP +Y +N DCT+TI+A+P I L F F +E
Sbjct: 201 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---------- 250
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
KYD+L+I P P I G P + S+ L L F TD GFSA Y
Sbjct: 251 KYDYLEIEGSEP---PTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 302
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/170 (28%), Positives = 70/170 (41%), Gaps = 24/170 (14%)
Query: 115 SSGSMLYIKFTSDYARQGAGFSLRY---EIFKTGSED--------CSKNFTSPNGTIESP 163
S GS + DY QGA E+F S+ C N P+GT SP
Sbjct: 463 SLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSP 522
Query: 164 GFPEKYPHNLDCTFTILAKPKMEII-LQFLIFDLE--HDPLQVGEGDCKYDWLDIWDGIP 220
FP +Y N C + I A ++I + F FDLE +D L +G+G ++ D
Sbjct: 523 NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGG------EVGDPRT 576
Query: 221 HVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
+ L G + P + S + + L TD +V GF Y + +E
Sbjct: 577 VLQVLTGSF----VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKE 622
Score = 37.0 bits (84), Expect = 0.047
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 19/135 (14%)
Query: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWD 217
G I SPG+P+ YP+ C ++I + I + F E + +D L ++D
Sbjct: 2427 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----------FDVLQVYD 2476
Query: 218 GIPHVGPLIGKYCGTKTPS-ELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQ 276
G P++ G + + + S+ + L + D K GF RY F
Sbjct: 2477 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA--------FY 2528
Query: 277 CNVPLGMESGRIANE 291
C+ P G I ++
Sbjct: 2529 CSTPESPPHGYIISQ 2543
>gi|205277354 CUB and Sushi multiple domains 3 isoform 3 [Homo
sapiens]
Length = 3538
Score = 110 bits (274), Expect = 4e-24
Identities = 85/294 (28%), Positives = 129/294 (43%), Gaps = 72/294 (24%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG L +G TSP +P Y S+ C W++ A N+ I +NF F++E YD
Sbjct: 444 CGSNLQGP-SGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFE-EFDLE---IGYDT 498
Query: 88 IEIRDGDS--ESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYA---------------- 129
+ I DG + +L G+ P I+S S +++ +D +
Sbjct: 499 LTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKE 558
Query: 130 ------------RQGAGFS----LRYEI---FKTGSED--------------------CS 150
R+G GFS LR+E F+ E C
Sbjct: 559 SCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCL 618
Query: 151 KNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKY 210
NFT+P GT+ SP +PE Y +NL+C +TI++ P I L F FDLE ++
Sbjct: 619 SNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLE----------SQF 668
Query: 211 DWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
D+L + DG P++G + G + PS L S++ IL L F D +++ GF+ Y
Sbjct: 669 DFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITY 722
Score = 109 bits (272), Expect = 8e-24
Identities = 86/322 (26%), Positives = 134/322 (41%), Gaps = 77/322 (23%)
Query: 38 GYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDFIEIRDGDSES 97
G + SP YP+ Y ++ NC W + + +P +I L+FN F++E ++DF+ ++DGDS
Sbjct: 626 GTVLSPDYPEGYGNNLNCIWTIIS-DPGSRIHLSFND-FDLES---QFDFLAVKDGDSPE 680
Query: 98 ADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF--------------- 142
+ +LG G P + S+ +L ++F +D++ G GF++ Y F
Sbjct: 681 SPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINAR 740
Query: 143 ---------KTGSEDCSKNFTSPNGT---------------------------------- 159
+ S C + F GT
Sbjct: 741 RFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSG 800
Query: 160 -IESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWDG 218
I SPG+P Y +L+C + I A+P I + F F E YD L++ DG
Sbjct: 801 VILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTE----------LNYDVLEVHDG 850
Query: 219 IPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQCN 278
+ PL+G Y GT+ P L SS+ + L F TD + + +GF Y V + + C
Sbjct: 851 PNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESV---TVNTYSCL 907
Query: 279 VPLGMESGRIANEQISASSTYS 300
P GR S ST S
Sbjct: 908 DPGIPVHGRRYGHDFSIGSTVS 929
Score = 106 bits (265), Expect = 5e-23
Identities = 92/333 (27%), Positives = 133/333 (39%), Gaps = 82/333 (24%)
Query: 27 PCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPN--QKIVLNFNPHFEIEKHDCK 84
PCGG L +K G I SPGYP+ Y ++ NC W + PE Q V++F +H+
Sbjct: 1834 PCGGIL-TKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSF-----ATEHN-- 1885
Query: 85 YDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSL------- 137
+D ++ DG +A LG + G P + S+ + LY+ F SD + AGF L
Sbjct: 1886 WDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGL 1945
Query: 138 -----------------RYEIFKTGSEDCSK--------------------NFTSP---- 156
RY + S C + N+ P
Sbjct: 1946 DSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLA 2005
Query: 157 ---------NGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
+G I SPGFP YP +LDCT+TI + LQF+ F E
Sbjct: 2006 QCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTE---------- 2055
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLV 267
+D+L++ G +IG+ G + PS L S+T SL FH+D + K GF Y
Sbjct: 2056 TIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAY 2115
Query: 268 HQEPLENFQCNVPLGMESGRIANEQISASSTYS 300
+ C P +G + + T S
Sbjct: 2116 QLQ-----SCPDPRPFRNGFVIGNDFTVGQTIS 2143
Score = 97.4 bits (241), Expect = 3e-20
Identities = 83/295 (28%), Positives = 120/295 (40%), Gaps = 73/295 (24%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGGR + +G I SPGYP Y ++ C W++ +P + L F F+ E +D
Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEV-DPGNIVSLQFLA-FDTE---ASHDI 1364
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIIS---------------SGSMLYIKFTSDYA--- 129
+ + DG E+ LL + G++ P I S S S I+F+S A
Sbjct: 1365 LRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATAC 1424
Query: 130 ----------RQG--------------AGFSLRYEIFKTGSE----------------DC 149
R G G+ L+ E T + C
Sbjct: 1425 RDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPC 1484
Query: 150 SKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCK 209
N T +G I SP FP YPH+ DC +TI I L F+ F +E +
Sbjct: 1485 GGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPN---------- 1534
Query: 210 YDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
YD+L I+DG PLIG + +K P + SS+ + L F +D +V+ GF Y
Sbjct: 1535 YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEY 1589
Score = 90.1 bits (222), Expect = 5e-18
Identities = 81/308 (26%), Positives = 126/308 (40%), Gaps = 77/308 (25%)
Query: 27 PCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYD 86
PCGG S +G I SPG+P Y NCEW++ A EP I + F F+ E + YD
Sbjct: 790 PCGGHF-SAPSGVILSPGWPGYYKDSLNCEWVIEA-EPGHSIKITFE-RFQTELN---YD 843
Query: 87 FIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEI----- 141
+E+ DG + + LLG + G P + SS + +Y+ FT+D +R GF + YE
Sbjct: 844 VLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNT 903
Query: 142 ------------------FKTGSED-----------------CSKN--FTSP-------- 156
F GS C KN ++ P
Sbjct: 904 YSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALC 963
Query: 157 NGTIESP-------GFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCK 209
G + P G+PE YP++L+CT+T+ + F F LE
Sbjct: 964 GGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLED----------H 1013
Query: 210 YDWLDIWDGIPHVGPLIGKYCGTKTPSELRS---STGILSLTFHTDMAVAKDGFSARYYL 266
+D+L I + PL + G+ P + + L F +D +++ +GF+ +
Sbjct: 1014 HDYLLITENGSFTQPL-ARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1072
Query: 267 VHQEPLEN 274
+ EP E+
Sbjct: 1073 YNLEPCED 1080
Score = 75.9 bits (185), Expect = 9e-14
Identities = 41/116 (35%), Positives = 66/116 (56%), Gaps = 7/116 (6%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG + + + G I SPGYP +YP+ Q+C W+V P P I +NF + + + YDF
Sbjct: 2179 CGGNITAMN-GTIYSPGYPDEYPNFQDCFWLVRVP-PGNGIYINFT----VLQTEPIYDF 2232
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
I + DG +++ +G+ GN A ++ S+ + + IKF SD+ G F L Y ++
Sbjct: 2233 ITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGF-FVLSYHAYQ 2287
Score = 75.5 bits (184), Expect = 1e-13
Identities = 44/132 (33%), Positives = 64/132 (48%), Gaps = 15/132 (11%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C NGTIESPGFP YP+ +CT+ I+A+ + I + F F LE +
Sbjct: 65 CGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEE--------- 115
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVH 268
YD+L ++DG PH + G P + S+ + SL +D AV+ GF V+
Sbjct: 116 -YDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFK-----VY 169
Query: 269 QEPLENFQCNVP 280
E L++ C P
Sbjct: 170 YEELQSSSCGNP 181
Score = 72.8 bits (177), Expect = 8e-13
Identities = 69/297 (23%), Positives = 118/297 (39%), Gaps = 77/297 (25%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CG + + G + SP YP +Y ++ C +Y+ + +N + H + D
Sbjct: 1137 CGASATNNE-GILLSPNYPLNYENNHEC---IYSIQVQAGKGINISAR---TFHLAQGDV 1189
Query: 88 IEIRDGDSESADLLGKHCG-NIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK-TG 145
++I DG ++ LLG G ++ T+ S+ + L+++F SD GF L Y F+ +
Sbjct: 1190 LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSH 1249
Query: 146 SED------------------------CSKNFTSPNGTI--------------------- 160
ED C+ +T ++
Sbjct: 1250 CEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAE 1309
Query: 161 -------ESPG------FPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGD 207
ES G +P Y +NL C + I P + LQFL FD E
Sbjct: 1310 CGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTE---------- 1359
Query: 208 CKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
+D L +WDG P L+ + G+ P + S+ I+++ F TD ++K GF+ ++
Sbjct: 1360 ASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQF 1416
Score = 72.4 bits (176), Expect = 1e-12
Identities = 44/138 (31%), Positives = 69/138 (50%), Gaps = 8/138 (5%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG L + G I SPG+P YP+ NC W++ A E N +I + F F +E+ +YD+
Sbjct: 65 CGGTLKGLN-GTIESPGFPYGYPNGANCTWVIIAEERN-RIQIVFQS-FALEE---EYDY 118
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSE 147
+ + DG + + G PP + S+ S+ ++ TSD+A GF + YE ++ S
Sbjct: 119 LSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSS- 177
Query: 148 DCSKNFTSPNGTIESPGF 165
C P G + F
Sbjct: 178 -CGNPGVPPKGVLYGTRF 194
Score = 70.1 bits (170), Expect = 5e-12
Identities = 83/345 (24%), Positives = 128/345 (37%), Gaps = 85/345 (24%)
Query: 23 QPDPP-----CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFE 77
QP PP CGG L +G+I SP +P YP ++C+W + + I L F F
Sbjct: 1474 QPSPPVCIAPCGGNLTGS-SGFILSPNFPHPYPHSRDCDWTITV-NADYVISLAFIS-FS 1530
Query: 78 IEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPPTIISS-----------GSMLYIKFTS 126
IE + YDF+ I DG ++ L+G + P I SS GS+ Y F
Sbjct: 1531 IEPN---YDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHL 1587
Query: 127 DYARQ-------------GAGFSLRYEIFKTGSEDCSKNF-------------------- 153
+Y + G + Y++ T + C +
Sbjct: 1588 EYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGW 1647
Query: 154 ---------------TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLE- 197
T GT+ SP +P+ Y +C ++I + + QF+ F
Sbjct: 1648 NRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSL 1707
Query: 198 HDPLQVGEGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAK 257
HD ++V +G + L + L G + G P SS +++ F + +
Sbjct: 1708 HDVVEVYDGPTQQSSL--------LSSLSGSHSGESLP---LSSGNQITIRFTSVGPITA 1756
Query: 258 DGFSARYYLVHQEPLENFQC-NVPLGMESGRIANEQISASSTYSD 301
GF Y V + + QC +VP RI NE SS D
Sbjct: 1757 KGFHFVYQAVPR--TSSTQCSSVPEPRFGRRIGNEFAVGSSVLFD 1799
Score = 69.7 bits (169), Expect = 7e-12
Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 12/121 (9%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C N T+ NGTI SPG+P++YP+ DC + + P I + F + L+ +P+
Sbjct: 2179 CGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTV--LQTEPI------- 2229
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVH 268
YD++ +WDG P IG++ G + S++ + + FH+D + GF Y +
Sbjct: 2230 -YDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTS--GFFVLSYHAY 2286
Query: 269 Q 269
Q
Sbjct: 2287 Q 2287
Score = 62.4 bits (150), Expect = 1e-09
Identities = 39/116 (33%), Positives = 63/116 (54%), Gaps = 10/116 (8%)
Query: 28 CGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCKYDF 87
CGG + +G I+SP +P +Y ++ +C W + A EP I L F F++E+ KYD+
Sbjct: 241 CGGTMRGS-SGIISSPSFPNEYHNNADCTWTIVA-EPGDTISLIFT-DFQMEE---KYDY 294
Query: 88 IEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFK 143
+EI + + L G + PP IIS+ + L + F +D + GFS Y++ K
Sbjct: 295 LEIEGSEPPTIWLSGMN----IPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQVKK 346
Score = 58.9 bits (141), Expect = 1e-08
Identities = 70/301 (23%), Positives = 113/301 (37%), Gaps = 79/301 (26%)
Query: 25 DPPCGGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKHDCK 84
D CGG + +G I SPGYP+ YP+ NC W V + + NF+ F +E H
Sbjct: 960 DALCGGDVRGP-SGTILSPGYPEFYPNSLNCTWTVDVTH-GKGVQFNFHT-FHLEDH--- 1013
Query: 85 YDFIEIRDGDSESADLLGKHCGNIAPPTI---ISSGSMLYIKFTSDYARQGAGFSLRYE- 140
+D++ I + S + L + G+ PPTI + ++F SD++ GF++ +
Sbjct: 1014 HDYLLITENGSFTQP-LARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSE 1072
Query: 141 -----------------------IFKTGSEDCSKNF------------------------ 153
I T + CS +
Sbjct: 1073 YNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPR 1132
Query: 154 ---------TSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVG 204
T+ G + SP +P Y +N +C ++I + I + F L
Sbjct: 1133 CVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHL-------A 1185
Query: 205 EGDCKYDWLDIWDGIPHVGPLIGKYCGTKTPS-ELRSSTGILSLTFHTDMAVAKDGFSAR 263
+GD L I+DG L+G + G L S++ L L F++D +GF
Sbjct: 1186 QGDV----LKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLV 1241
Query: 264 Y 264
Y
Sbjct: 1242 Y 1242
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/152 (29%), Positives = 73/152 (48%), Gaps = 17/152 (11%)
Query: 17 RHQVRGQPDPPC-----GGRLNSKDAGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLN 71
R Q+ G P P C L G I SPGYP YP+ Q C W + + E I +
Sbjct: 2338 RLQMDGAP-PVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSI-SVEKGYNITM- 2394
Query: 72 FNPHFEIEKHDCKYDFIEIRDGDSESADLLGKHCGNIAPP-TIISSGSMLYIKFTSDYAR 130
F F+ EK ++D +++ DG + + +L G+ + I S+G +++++++D+
Sbjct: 2395 FVEFFQTEK---EFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGN 2451
Query: 131 QGAGFSLRYEIFKTGSEDCSKNFTSPNGTIES 162
GF +RY F CS + P+G I S
Sbjct: 2452 NKKGFRIRYIAFY-----CSTPESPPHGYIIS 2478
Score = 57.4 bits (137), Expect = 3e-08
Identities = 42/116 (36%), Positives = 53/116 (45%), Gaps = 14/116 (12%)
Query: 149 CSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDC 208
C +G I SP FP +Y +N DCT+TI+A+P I L F F +E
Sbjct: 241 CGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEE---------- 290
Query: 209 KYDWLDIWDGIPHVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARY 264
KYD+L+I P P I G P + S+ L L F TD GFSA Y
Sbjct: 291 KYDYLEIEGSEP---PTIW-LSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPY 342
Score = 53.9 bits (128), Expect = 4e-07
Identities = 48/170 (28%), Positives = 70/170 (41%), Gaps = 24/170 (14%)
Query: 115 SSGSMLYIKFTSDYARQGAGFSLRY---EIFKTGSED--------CSKNFTSPNGTIESP 163
S GS + DY QGA E+F S+ C N P+GT SP
Sbjct: 399 SLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSP 458
Query: 164 GFPEKYPHNLDCTFTILAKPKMEII-LQFLIFDLE--HDPLQVGEGDCKYDWLDIWDGIP 220
FP +Y N C + I A ++I + F FDLE +D L +G+G ++ D
Sbjct: 459 NFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGG------EVGDPRT 512
Query: 221 HVGPLIGKYCGTKTPSELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQE 270
+ L G + P + S + + L TD +V GF Y + +E
Sbjct: 513 VLQVLTGSF----VPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKE 558
Score = 37.0 bits (84), Expect = 0.047
Identities = 32/135 (23%), Positives = 54/135 (40%), Gaps = 19/135 (14%)
Query: 158 GTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQVGEGDCKYDWLDIWD 217
G I SPG+P+ YP+ C ++I + I + F E + +D L ++D
Sbjct: 2363 GVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKE----------FDVLQVYD 2412
Query: 218 GIPHVGPLIGKYCGTKTPS-ELRSSTGILSLTFHTDMAVAKDGFSARYYLVHQEPLENFQ 276
G P++ G + + + S+ + L + D K GF RY F
Sbjct: 2413 GPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIA--------FY 2464
Query: 277 CNVPLGMESGRIANE 291
C+ P G I ++
Sbjct: 2465 CSTPESPPHGYIISQ 2479
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,341,287
Number of Sequences: 37866
Number of extensions: 1089712
Number of successful extensions: 3113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 100
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 2009
Number of HSP's gapped (non-prelim): 492
length of query: 555
length of database: 18,247,518
effective HSP length: 107
effective length of query: 448
effective length of database: 14,195,856
effective search space: 6359743488
effective search space used: 6359743488
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.