Search of human proteins with 41393602

Search of human proteins with 41393602

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|41393602 complement component 1, s subcomponent precursor
[Homo sapiens]
         (688 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502495 complement component 1, s subcomponent precursor [Hom...  1464   0.0  
gi|41393602 complement component 1, s subcomponent precursor [Ho...  1464   0.0  
gi|21264359 mannan-binding lectin serine protease 1 isoform 2 pr...   477   e-134
gi|66347875 complement component 1, r subcomponent [Homo sapiens]     474   e-133
gi|21264363 mannan-binding lectin serine protease 2 isoform 1 pr...   465   e-131
gi|21264357 mannan-binding lectin serine protease 1 isoform 1 pr...   443   e-124
gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [H...   281   1e-75
gi|7706083 complement component 1, r subcomponent-like precursor...   179   8e-45
gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]         166   9e-41
gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]       164   3e-40
gi|45580723 haptoglobin-related protein [Homo sapiens]                156   7e-38
gi|21264361 mannan-binding lectin serine protease 2 isoform 2 pr...   140   4e-33
gi|6912724 tolloid-like 2 [Homo sapiens]                              137   3e-32
gi|110578663 hypothetical protein LOC203074 [Homo sapiens]            132   1e-30
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]         130   3e-30
gi|4506115 protein C [Homo sapiens]                                   130   5e-30
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...   128   2e-29
gi|33695155 hepsin [Homo sapiens]                                     128   2e-29
gi|4504481 hepsin [Homo sapiens]                                      128   2e-29
gi|4503635 coagulation factor II preproprotein [Homo sapiens]         126   8e-29
gi|22547221 tolloid-like 1 [Homo sapiens]                             126   8e-29
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          126   8e-29
gi|4503625 coagulation factor X preproprotein [Homo sapiens]          125   1e-28
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...   124   2e-28
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...   122   1e-27
gi|62526043 chymotrypsin C preproprotein [Homo sapiens]               117   3e-26
gi|118498341 chymotrypsin B1 [Homo sapiens]                           117   3e-26
gi|11415040 matriptase [Homo sapiens]                                 117   4e-26
gi|110815798 ovochymase 1 [Homo sapiens]                              117   4e-26
gi|118498350 chymotrypsin B2 [Homo sapiens]                           115   1e-25

>gi|4502495 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score = 1464 bits (3789), Expect = 0.0
 Identities = 688/688 (100%), Positives = 688/688 (100%)

Query: 1   MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE 60
           MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE
Sbjct: 1   MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE 60

Query: 61  LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF 120
           LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF
Sbjct: 61  LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF 120

Query: 121 TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180
           TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF
Sbjct: 121 TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180

Query: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF 240
           TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF
Sbjct: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF 240

Query: 241 VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP 300
           VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP
Sbjct: 241 VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP 300

Query: 301 NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG 360
           NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG
Sbjct: 301 NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG 360

Query: 361 IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK 420
           IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK
Sbjct: 361 IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK 420

Query: 421 CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN 480
           CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN
Sbjct: 421 CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN 480

Query: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540
           REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK
Sbjct: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540

Query: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV 600
           MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV
Sbjct: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV 600

Query: 601 EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 660
           EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG
Sbjct: 601 EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 660

Query: 661 TYGLYTRVKNYVDWIMKTMQENSTPRED 688
           TYGLYTRVKNYVDWIMKTMQENSTPRED
Sbjct: 661 TYGLYTRVKNYVDWIMKTMQENSTPRED 688


>gi|41393602 complement component 1, s subcomponent precursor [Homo
           sapiens]
          Length = 688

 Score = 1464 bits (3789), Expect = 0.0
 Identities = 688/688 (100%), Positives = 688/688 (100%)

Query: 1   MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE 60
           MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE
Sbjct: 1   MWCIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIE 60

Query: 61  LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF 120
           LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF
Sbjct: 61  LSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERF 120

Query: 121 TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180
           TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF
Sbjct: 121 TGFAAYYVATDINECTDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180

Query: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF 240
           TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF
Sbjct: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVF 240

Query: 241 VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP 300
           VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP
Sbjct: 241 VAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTP 300

Query: 301 NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG 360
           NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG
Sbjct: 301 NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCG 360

Query: 361 IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK 420
           IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK
Sbjct: 361 IPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPK 420

Query: 421 CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN 480
           CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN
Sbjct: 421 CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWAGGALINEYWVLTAAHVVEGN 480

Query: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540
           REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK
Sbjct: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540

Query: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV 600
           MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV
Sbjct: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVKV 600

Query: 601 EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 660
           EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG
Sbjct: 601 EKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG 660

Query: 661 TYGLYTRVKNYVDWIMKTMQENSTPRED 688
           TYGLYTRVKNYVDWIMKTMQENSTPRED
Sbjct: 661 TYGLYTRVKNYVDWIMKTMQENSTPRED 688


>gi|21264359 mannan-binding lectin serine protease 1 isoform 2
           precursor [Homo sapiens]
          Length = 728

 Score =  477 bits (1228), Expect = e-134
 Identities = 274/724 (37%), Positives = 401/724 (55%), Gaps = 66/724 (9%)

Query: 3   CIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELS 62
           C  L    A       M+G+I SP YP +YPS+ E +W+I VP+G+ I LYF H ++E S
Sbjct: 11  CFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESS 70

Query: 63  ENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTG 122
             C YD V++ + D      CG+ +++   +P  E    P + + + F+SDFSNEERFTG
Sbjct: 71  YLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTG 130

Query: 123 FAAYYVATDINECTDFVD--VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180
           F A+Y+A D++EC +  D  + C H+C+N+IGGY+CSC   Y LH D + C V CS ++F
Sbjct: 131 FDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLF 190

Query: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRRED-FDVEAADSAGNCLDSLV 239
           T   G I SP++P PYP++S C Y I LE+GF  +V L+ ED FD+E         D + 
Sbjct: 191 TQRTGVITSPDFPNPYPKSSECLYTIELEEGF--MVNLQFEDIFDIEDHPEVPCPYDYIK 248

Query: 240 FVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDT 299
              G +  GP+CG   P P  I T+S+++ I+F +D +G+ +GW+L Y      CP+   
Sbjct: 249 IKVGPKVLGPFCGEKAPEP--ISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQP 306

Query: 300 P-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVD 358
           P +   EP++AKY F+D V ++C  G++V++  V   +F   C  +G WSN    C+ VD
Sbjct: 307 PVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVD 366

Query: 359 CGIPESIENGKV---EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLG 415
           C  P  +E+G +        T + S I+Y+C+EPYY M N   G Y C+  G W+N+VLG
Sbjct: 367 CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLG 426

Query: 416 PELPKCVPVCGVPREPFEE-KQRIIGGSDADIKNFPWQVFF---------DNPWAG-GAL 464
             LP C+P CG P        +RIIGG +A+   FPWQ            ++ W G GAL
Sbjct: 427 RSLPTCLPECGQPSRSLPSLVKRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGAL 486

Query: 465 INEYWVLTAAHVVEGNREP-----------TMYVGSTSVQTSRLAKSKMLTPEHVFIHPG 513
           ++  W+LTAAHV+   R             T+Y+G   V+    A +   +   V +HP 
Sbjct: 487 LSASWILTAAHVLRSQRRDTTVIPVSKEHVTVYLGLHDVRDKSGAVNS--SAARVVLHPD 544

Query: 514 WKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWG-- 571
           + +        N+++DIALV+L++PV +GP V P+CLP    +       LGL++GWG  
Sbjct: 545 FNI-------QNYNHDIALVQLQEPVPLGPHVMPVCLPRLEPE-GPAPHMLGLVAGWGIS 596

Query: 572 ----------RTEKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG- 620
                      +  R  +  L+  +LPV P  +CK    E  + +   Y  T NM CAG 
Sbjct: 597 NPNVTVDEIISSGTRTLSDVLQYVKLPVVPHAECK-TSYESRSGN---YSVTENMFCAGY 652

Query: 621 GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWG--PQCGT---YGLYTRVKNYVDWI 675
            E G D+C GDSGGAF + D   + ++   GLVSWG   +CG+   YG+YT+V NYVDW+
Sbjct: 653 YEGGKDTCLGDSGGAFVIFDDLSQ-RWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWV 711

Query: 676 MKTM 679
            + M
Sbjct: 712 WEQM 715


>gi|66347875 complement component 1, r subcomponent [Homo sapiens]
          Length = 705

 Score =  474 bits (1219), Expect = e-133
 Identities = 268/696 (38%), Positives = 387/696 (55%), Gaps = 50/696 (7%)

Query: 19  MYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTE 78
           ++GE+ SP +P+ YP+  E +  I VP GY + L F   D+E SE C YD V+I +    
Sbjct: 25  LFGEVTSPLFPKPYPNNFETTTVITVPTGYRVKLVFQQFDLEPSEGCFYDYVKISADKKS 84

Query: 79  EGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFT-----GFAAYYVATDIN 133
            GR CGQ  S   + P  +EF    NK+ + F +DFSNEE  T     GF AYY A D++
Sbjct: 85  LGRFCGQLGSPLGNPPGKKEFMSQGNKMLLTFHTDFSNEENGTIMFYKGFLAYYQAVDLD 144

Query: 134 ECTDFVDV-------PCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGE 186
           EC     +        C H C+N++GGYFCSC P Y L +D  +C   CS +++T   G 
Sbjct: 145 ECASRSKLGEEDPQPQCQHLCHNYVGGYFCSCRPGYELQEDRHSCQAECSSELYTEASGY 204

Query: 187 IASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ 246
           I+S  YP+ YP + RC Y IR+E+G  + +    E FD++         D L   A  + 
Sbjct: 205 ISSLEYPRSYPPDLRCNYSIRVERGLTLHLKF-LEPFDIDDHQQVHCPYDQLQIYANGKN 263

Query: 247 FGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDTPN--SVW 304
            G +CG     P +++T SNA+D++F TD +G  +GWKLRY  + + CP+  T +  ++ 
Sbjct: 264 IGEFCGK--QRPPDLDTSSNAVDLLFFTDESGDSRGWKLRYTTEIIKCPQPKTLDEFTII 321

Query: 305 EPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPES 364
           +  + +Y FRD    TC  G++++EG     SF + CQ +G W  +  +C+  DCG P +
Sbjct: 322 QNLQPQYQFRDYFIATCKQGYQLIEGNQVLHSFTAVCQDDGTWHRAMPRCKIKDCGQPRN 381

Query: 365 IENGKVEDPES---TLFGSVIRYTCEEPYYYMENGGG------GEYHCAGNGSWVNEVLG 415
           + NG      +     + + I+Y C EPYY M+   G      G Y C   G W NE  G
Sbjct: 382 LPNGDFRYTTTMGVNTYKARIQYYCHEPYYKMQTRAGSRESEQGVYTCTAQGIWKNEQKG 441

Query: 416 PELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFD-NPWAGGALINEYWVLTAA 474
            ++P+C+PVCG P  P E++QRIIGG  A + NFPWQVF + +   GGAL+ + W+LTAA
Sbjct: 442 EKIPRCLPVCGKPVNPVEQRQRIIGGQKAKMGNFPWQVFTNIHGRGGGALLGDRWILTAA 501

Query: 475 HVV-------EGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFD 527
           H +       + N    +++G T+V+   L K        V +HP ++     +   NF+
Sbjct: 502 HTLYPKEHEAQSNASLDVFLGHTNVE--ELMKLGNHPIRRVSVHPDYR----QDESYNFE 555

Query: 528 NDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARL 587
            DIAL+ L++ V +GP + PICLP   + Y+L  G +G +SG+G  E++  A  L+  RL
Sbjct: 556 GDIALLELENSVTLGPNLLPICLPDNDTFYDL--GLMGYVSGFGVMEEK-IAHDLRFVRL 612

Query: 588 PVAPLRKCKEVKVEKPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTK 646
           PVA  + C+     K   D    VF+ NM CAG      D+C+GDSGG FAV+DPN   +
Sbjct: 613 PVANPQACENWLRGKNRMD----VFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPN-TDR 667

Query: 647 FYAAGLVSWGPQCGT-YGLYTRVKNYVDWIMKTMQE 681
           + A G+VSWG  C   YG YT+V NYVDWI K M+E
Sbjct: 668 WVATGIVSWGIGCSRGYGFYTKVLNYVDWIKKEMEE 703


>gi|21264363 mannan-binding lectin serine protease 2 isoform 1
           precursor [Homo sapiens]
          Length = 686

 Score =  465 bits (1196), Expect = e-131
 Identities = 264/681 (38%), Positives = 366/681 (53%), Gaps = 42/681 (6%)

Query: 14  YAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQII 73
           + EP ++G + SP +P  Y ++ E+ W +  P GY + LYFTH D+ELS  C YD V++ 
Sbjct: 22  WPEP-VFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS 80

Query: 74  SGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDIN 133
           SG      LCGQ S++   +P  + F    + L + F+SD+SNE+ FTGF A+Y A DI+
Sbjct: 81  SGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDID 140

Query: 134 ECTDFV-DVP-CSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPN 191
           EC     + P C H C+N +GG++CSC   Y LH + + C   CSG VFT   GE++SP 
Sbjct: 141 ECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTCSALCSGQVFTQRSGELSSPE 200

Query: 192 YPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYC 251
           YP+PYP+ S C Y I LE+GF V++    E FDVE         D L       + GP+C
Sbjct: 201 YPRPYPKLSSCTYSISLEEGFSVILDF-VESFDVETHPETLCPYDFLKIQTDREEHGPFC 259

Query: 252 GHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCP-KEDTPNSVWEPAKAK 310
           G   P    IETKSN + I F TD +G   GWK+ Y     PCP     PN    P +AK
Sbjct: 260 GKTLPH--RIETKSNTVTITFVTDESGDHTGWKIHYTSTAQPCPYPMAPPNGHVSPVQAK 317

Query: 311 YVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVDCGIPESIENGKV 370
           Y+ +D   I C  G+E+++G +   SF + CQ +G W      C  VDCG P+ + +G+V
Sbjct: 318 YILKDSFSIFCETGYELLQGHLPLKSFTAVCQKDGSWDRPMPACSIVDCGPPDDLPSGRV 377

Query: 371 E---DPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGV 427
           E    P  T + +VI+Y+CEE +Y M+    G+Y C  +G W +      LP C PVCG+
Sbjct: 378 EYITGPGVTTYKAVIQYSCEETFYTMK-VNDGKYVCEADGFWTSSKGEKSLPVCEPVCGL 436

Query: 428 PREPFEEKQRIIGGSDADIKNFPWQV-FFDNPWAGGALINEYWVLTAAHVVEGNREPTMY 486
                    RI GG  A   +FPWQV       A GAL+ + WVLTAAH V   +     
Sbjct: 437 SAR--TTGGRIYGGQKAKPGDFPWQVLILGGTTAAGALLYDNWVLTAAHAVYEQKH---- 490

Query: 487 VGSTSVQTSRLAKSKMLTP-------EHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPV 539
               S    R+   K L+P       E VFIH G+           FDNDIAL++L + V
Sbjct: 491 --DASALDIRMGTLKRLSPHYTQAWSEAVFIHEGY------THDAGFDNDIALIKLNNKV 542

Query: 540 KMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKEVK 599
            +   ++PICLP   ++  +   D+G  SGWG T++   A  L    +P+   +KC    
Sbjct: 543 VINSNITPICLPRKEAESFMRTDDIGTASGWGLTQRGFLARNLMYVDIPIVDHQKC-TAA 601

Query: 600 VEKPTADAEAYVFTPNMICAGGEK-GMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP- 657
            EKP     +   T NM+CAG E  G DSC+GDSGGA    D ++  +++  G+VSWG  
Sbjct: 602 YEKPPYPRGS--VTANMLCAGLESGGKDSCRGDSGGALVFLD-SETERWFVGGIVSWGSM 658

Query: 658 ---QCGTYGLYTRVKNYVDWI 675
              + G YG+YT+V NY+ WI
Sbjct: 659 NCGEAGQYGVYTKVINYIPWI 679


>gi|21264357 mannan-binding lectin serine protease 1 isoform 1
           precursor [Homo sapiens]
          Length = 699

 Score =  443 bits (1140), Expect = e-124
 Identities = 251/707 (35%), Positives = 377/707 (53%), Gaps = 56/707 (7%)

Query: 3   CIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELS 62
           C  L    A       M+G+I SP YP +YPS+ E +W+I VP+G+ I LYF H ++E S
Sbjct: 11  CFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESS 70

Query: 63  ENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTG 122
             C YD V++ + D      CG+ +++   +P  E    P + + + F+SDFSNEERFTG
Sbjct: 71  YLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTG 130

Query: 123 FAAYYVATDINECTDFVD--VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180
           F A+Y+A D++EC +  D  + C H+C+N+IGGY+CSC   Y LH D + C V CS ++F
Sbjct: 131 FDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLF 190

Query: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRRED-FDVEAADSAGNCLDSLV 239
           T   G I SP++P PYP++S C Y I LE+GF  +V L+ ED FD+E         D + 
Sbjct: 191 TQRTGVITSPDFPNPYPKSSECLYTIELEEGF--MVNLQFEDIFDIEDHPEVPCPYDYIK 248

Query: 240 FVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDT 299
              G +  GP+CG   P P  I T+S+++ I+F +D +G+ +GW+L Y      CP+   
Sbjct: 249 IKVGPKVLGPFCGEKAPEP--ISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQP 306

Query: 300 P-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVD 358
           P +   EP++AKY F+D V ++C  G++V++  V   +F   C  +G WSN    C+ VD
Sbjct: 307 PVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVD 366

Query: 359 CGIPESIENGKV---EDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLG 415
           C  P  +E+G +        T + S I+Y+C+EPYY M N   G Y C+  G W+N+VLG
Sbjct: 367 CRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLG 426

Query: 416 PELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFFDN----PWAGGALINEYWVL 471
             LP C+PVCG+P+   +   RI  G  A     PW     +    P+ GG+L+   W++
Sbjct: 427 RSLPTCLPVCGLPKFSRKLMARIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIV 486

Query: 472 TAAHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPE--HVFIHPGWKL------------- 516
           TAAH +  + +P         +   L  S +L+P    + +   W+L             
Sbjct: 487 TAAHCLHQSLDP---------EDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKH 537

Query: 517 --LEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTE 574
             L        F+ND+ALV L +   +   V PICLP    +    +G + ++SGWG+  
Sbjct: 538 TTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP----EGPQQEGAMVIVSGWGKQF 593

Query: 575 KRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSG 633
            +     L    +P+     C     +K  A  +  V T +MICAG  E G D+C GDSG
Sbjct: 594 LQRFPETLMEIEIPIVDHSTC-----QKAYAPLKKKV-TRDMICAGEKEGGKDACAGDSG 647

Query: 634 GAFAVQDPNDKTKFYAAGLVSWGPQCG---TYGLYTRVKNYVDWIMK 677
           G     +  ++ ++Y  G VSWG  CG    YG+Y+ + +  DWI +
Sbjct: 648 GPMVTLN-RERGQWYLVGTVSWGDDCGKKDRYGVYSYIHHNKDWIQR 693


>gi|73623026 mannan-binding lectin serine protease 1 isoform 3 [Homo
           sapiens]
          Length = 380

 Score =  281 bits (720), Expect = 1e-75
 Identities = 142/374 (37%), Positives = 219/374 (58%), Gaps = 8/374 (2%)

Query: 3   CIVLFSLLAWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELS 62
           C  L    A       M+G+I SP YP +YPS+ E +W+I VP+G+ I LYF H ++E S
Sbjct: 11  CFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESS 70

Query: 63  ENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTG 122
             C YD V++ + D      CG+ +++   +P  E    P + + + F+SDFSNEERFTG
Sbjct: 71  YLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTG 130

Query: 123 FAAYYVATDINECTDFVD--VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVF 180
           F A+Y+A D++EC +  D  + C H+C+N+IGGY+CSC   Y LH D + C V CS ++F
Sbjct: 131 FDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLF 190

Query: 181 TALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRRED-FDVEAADSAGNCLDSLV 239
           T   G I SP++P PYP++S C Y I LE+GF  +V L+ ED FD+E         D + 
Sbjct: 191 TQRTGVITSPDFPNPYPKSSECLYTIELEEGF--MVNLQFEDIFDIEDHPEVPCPYDYIK 248

Query: 240 FVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKEDT 299
              G +  GP+CG   P P  I T+S+++ I+F +D +G+ +GW+L Y      CP+   
Sbjct: 249 IKVGPKVLGPFCGEKAPEP--ISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQP 306

Query: 300 P-NSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYSTCQSNGKWSNSKLKCQPVD 358
           P +   EP++AKY F+D V ++C  G++V++  V   +F   C  +G WSN    C+  +
Sbjct: 307 PVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKKNE 366

Query: 359 CGIPESIENGKVED 372
             +   +++ +V +
Sbjct: 367 IDLESELKSEQVTE 380


>gi|7706083 complement component 1, r subcomponent-like precursor
           [Homo sapiens]
          Length = 487

 Score =  179 bits (454), Expect = 8e-45
 Identities = 115/307 (37%), Positives = 157/307 (51%), Gaps = 31/307 (10%)

Query: 386 CEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDAD 445
           C+EPYY  +    G   CA  G+W +   G E+ +C+PVCG P  P  + Q  +G S A 
Sbjct: 195 CQEPYY--QAAAAGALTCATPGTWKDRQDGEEVLQCMPVCGRPVTPIAQNQTTLGSSRAK 252

Query: 446 IKNFPWQVFFD-NPWAGGALINEYWVLTAAHVV--------EGNREPTMYVGSTSVQTSR 496
           + NFPWQ F   +   GGAL+ + W+LTAAH V          N+   +++G T++    
Sbjct: 253 LGNFPWQAFTSIHGRGGGALLGDRWILTAAHTVYPKDSVSLRKNQSVNVFLGHTAI--DE 310

Query: 497 LAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSD 556
           + K        V +HP ++  E      NF  DIAL+ L+  + +GP V P+CLP   + 
Sbjct: 311 MLKLGNHPVHRVVVHPDYRQNE----SHNFSGDIALLELQHSIPLGPNVLPVCLPDNETL 366

Query: 557 YNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRKCKE--VKVEKPTADAEAYVFTP 614
           Y    G LG +SG+G  E       LK +RLPVAP   C     K ++P       VF+ 
Sbjct: 367 YR--SGLLGYVSGFG-MEMGWLTTELKYSRLPVAPREACNAWLQKRQRPE------VFSD 417

Query: 615 NMICAGGEKGMDS-CKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT-YGLYTRVKNYV 672
           NM C G E    S C+GDSG  + V D N    + A G+VSWG  CG  Y  YT+V +YV
Sbjct: 418 NMFCVGDETQRHSVCQGDSGSVYVVWD-NHAHHWVATGIVSWGIGCGEGYDFYTKVLSYV 476

Query: 673 DWIMKTM 679
           DWI   M
Sbjct: 477 DWIKGVM 483



 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 44/143 (30%), Positives = 69/143 (48%), Gaps = 10/143 (6%)

Query: 1   MWCIVLFSLL------AWVYAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYF 54
           MW ++L+ +L        V     +  ++ SP YP+ Y    E S DI+ PEG+ + L F
Sbjct: 24  MWWLLLWGVLQACPTRGSVLLAQELPQQLTSPGYPEPYGKGQESSTDIKAPEGFAVRLVF 83

Query: 55  THLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDF 114
              D+E S++CA DSV I    ++  + CGQ+ S     P   EF      L++ F++  
Sbjct: 84  QDFDLEPSQDCAGDSVTISFVGSDPSQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQP 143

Query: 115 SNEER----FTGFAAYYVATDIN 133
           S+E +      GF A Y    +N
Sbjct: 144 SSENKTAHLHKGFLALYQTVAVN 166



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 10/102 (9%)

Query: 186 EIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDR 245
           ++ SP YP+PY +       I+  +GF   V L  +DFD+E +        ++ FV  D 
Sbjct: 51  QLTSPGYPEPYGKGQESSTDIKAPEGF--AVRLVFQDFDLEPSQDCAGDSVTISFVGSDP 108

Query: 246 QFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQKK 281
               +CG         PG     +   +L + F+T  + + K
Sbjct: 109 --SQFCGQQGSPLGRPPGQREFVSSGRSLRLTFRTQPSSENK 148


>gi|4826762 haptoglobin isoform 1 preproprotein [Homo sapiens]
          Length = 406

 Score =  166 bits (419), Expect = 9e-41
 Identities = 119/365 (32%), Positives = 168/365 (46%), Gaps = 47/365 (12%)

Query: 340 TCQSNGKWSNSKL-----KCQPVD-CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYM 393
           T     +W N  +     +C+  D C  P  I +G VE          +RY C+  YY +
Sbjct: 67  TLNDKKQWINKAVGDKLPECEADDGCPKPPEIAHGYVEHS--------VRYQCKN-YYKL 117

Query: 394 ENGGGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQ- 452
              G G Y       W+N+ +G +LP+C  VCG P+ P    QRI+GG      +FPWQ 
Sbjct: 118 RTEGDGVYTLNNEKQWINKAVGDKLPECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQA 177

Query: 453 --VFFDNPWAGGALINEYWVLTAA-HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVF 509
             V   N   G  LINE W+LT A ++   + E           T  + K +++  E V 
Sbjct: 178 KMVSHHNLTTGATLINEQWLLTTAKNLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVV 237

Query: 510 IHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISG 569
           +HP +  +           DI L++LK  V +   V PICLP  S DY  + G +G +SG
Sbjct: 238 LHPNYSQV-----------DIGLIKLKQKVSVNERVMPICLP--SKDYAEV-GRVGYVSG 283

Query: 570 WGRTEKRDRAVRLKAARLPVAPLRKC---------KEVKVEKPTADAEAYVFTPNMICAG 620
           WGR         LK   LPVA   +C          E K  K     +  +   +  CAG
Sbjct: 284 WGRNANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPEKKTPKSPVGVQP-ILNEHTFCAG 342

Query: 621 GEKGM-DSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGT--YGLYTRVKNYVDWIMK 677
             K   D+C GD+G AFAV D  + T +YA G++S+   C    YG+Y +V +  DW+ K
Sbjct: 343 MSKYQEDTCYGDAGSAFAVHDLEEDT-WYATGILSFDKSCAVAEYGVYVKVTSIQDWVQK 401

Query: 678 TMQEN 682
           T+ EN
Sbjct: 402 TIAEN 406



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 23/73 (31%), Positives = 33/73 (45%), Gaps = 9/73 (12%)

Query: 359 CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPEL 418
           C  P  I +G VE          +RY C+  YY +   G G Y       W+N+ +G +L
Sbjct: 33  CPKPPEIAHGYVEHS--------VRYQCKN-YYKLRTEGDGVYTLNDKKQWINKAVGDKL 83

Query: 419 PKCVPVCGVPREP 431
           P+C    G P+ P
Sbjct: 84  PECEADDGCPKPP 96


>gi|186910296 haptoglobin isoform 2 preproprotein [Homo sapiens]
          Length = 347

 Score =  164 bits (415), Expect = 3e-40
 Identities = 114/340 (33%), Positives = 159/340 (46%), Gaps = 41/340 (12%)

Query: 359 CGIPESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPEL 418
           C  P  I +G VE          +RY C+  YY +   G G Y       W+N+ +G +L
Sbjct: 33  CPKPPEIAHGYVEHS--------VRYQCKN-YYKLRTEGDGVYTLNNEKQWINKAVGDKL 83

Query: 419 PKCVPVCGVPREPFEEKQRIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAA- 474
           P+C  VCG P+ P    QRI+GG      +FPWQ   V   N   G  LINE W+LT A 
Sbjct: 84  PECEAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAK 143

Query: 475 HVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVR 534
           ++   + E           T  + K +++  E V +HP +  +           DI L++
Sbjct: 144 NLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV-----------DIGLIK 192

Query: 535 LKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPLRK 594
           LK  V +   V PICLP  S DY  + G +G +SGWGR         LK   LPVA   +
Sbjct: 193 LKQKVSVNERVMPICLP--SKDYAEV-GRVGYVSGWGRNANFKFTDHLKYVMLPVADQDQ 249

Query: 595 C---------KEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDK 644
           C          E K  K     +  +   +  CAG  K   D+C GD+G AFAV D  + 
Sbjct: 250 CIRHYEGSTVPEKKTPKSPVGVQP-ILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEED 308

Query: 645 TKFYAAGLVSWGPQCGT--YGLYTRVKNYVDWIMKTMQEN 682
           T +YA G++S+   C    YG+Y +V +  DW+ KT+ EN
Sbjct: 309 T-WYATGILSFDKSCAVAEYGVYVKVTSIQDWVQKTIAEN 347


>gi|45580723 haptoglobin-related protein [Homo sapiens]
          Length = 348

 Score =  156 bits (394), Expect = 7e-38
 Identities = 110/337 (32%), Positives = 158/337 (46%), Gaps = 41/337 (12%)

Query: 362 PESIENGKVEDPESTLFGSVIRYTCEEPYYYMENGGGGEYHCAGNGSWVNEVLGPELPKC 421
           P  I NG VE         + RY C+  YY +   G G Y       W+N+ +G +LP+C
Sbjct: 37  PPEIANGYVEH--------LFRYQCKN-YYRLRTEGDGVYTLNDKKQWINKAVGDKLPEC 87

Query: 422 VPVCGVPREPFEEKQRIIGGSDADIKNFPWQ---VFFDNPWAGGALINEYWVLTAA-HVV 477
             VCG P+ P    QRI+GG      +FPWQ   V   N   G  LINE W+LT A ++ 
Sbjct: 88  EAVCGKPKNPANPVQRILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLF 147

Query: 478 EGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKD 537
             + E           T  + K +++  E V +HP +  +           DI L++LK 
Sbjct: 148 LNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYHQV-----------DIGLIKLKQ 196

Query: 538 PVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAVRLKAARLPVAPL----- 592
            V +   V PICLP  S +Y  + G +G +SGWG+++       LK   LPVA       
Sbjct: 197 KVLVNERVMPICLP--SKNYAEV-GRVGYVSGWGQSDNFKLTDHLKYVMLPVADQYDCIT 253

Query: 593 ----RKCKEVKVEKPTADAEAYVFTPNMICAGGEKGM-DSCKGDSGGAFAVQDPNDKTKF 647
                 C + K  K     +  +   +  C G  K   D+C GD+G AFAV D  + T +
Sbjct: 254 HYEGSTCPKWKAPKSPVGVQP-ILNEHTFCVGMSKYQEDTCYGDAGSAFAVHDLEEDT-W 311

Query: 648 YAAGLVSWGPQCGT--YGLYTRVKNYVDWIMKTMQEN 682
           YAAG++S+   C    YG+Y +V +   W+ KT+ EN
Sbjct: 312 YAAGILSFDKSCAVAEYGVYVKVTSIQHWVQKTIAEN 348


>gi|21264361 mannan-binding lectin serine protease 2 isoform 2
           precursor [Homo sapiens]
          Length = 185

 Score =  140 bits (353), Expect = 4e-33
 Identities = 66/160 (41%), Positives = 97/160 (60%), Gaps = 3/160 (1%)

Query: 14  YAEPTMYGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQII 73
           + EP ++G + SP +P  Y ++ E+ W +  P GY + LYFTH D+ELS  C YD V++ 
Sbjct: 22  WPEP-VFGRLASPGFPGEYANDQERRWTLTAPPGYRLRLYFTHFDLELSHLCEYDFVKLS 80

Query: 74  SGDTEEGRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDIN 133
           SG      LCGQ S++   +P  + F    + L + F+SD+SNE+ FTGF A+Y A DI+
Sbjct: 81  SGAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEKPFTGFEAFYAAEDID 140

Query: 134 ECTDFV-DVP-CSHFCNNFIGGYFCSCPPEYFLHDDMKNC 171
           EC     + P C H C+N +GG++CSC   Y LH + + C
Sbjct: 141 ECQVAPGEAPTCDHHCHNHLGGFYCSCRAGYVLHRNKRTC 180



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 10/104 (9%)

Query: 183 LIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVA 242
           + G +ASP +P  Y  +    + +    G+++   L    FD+E +       D +   +
Sbjct: 26  VFGRLASPGFPGEYANDQERRWTLTAPPGYRL--RLYFTHFDLELSHLCE--YDFVKLSS 81

Query: 243 GDRQFGPYCGHGF------PGPLNIETKSNALDIIFQTDLTGQK 280
           G +     CG         PG     +  ++LDI F++D + +K
Sbjct: 82  GAKVLATLCGQESTDTERAPGKDTFYSLGSSLDITFRSDYSNEK 125


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score =  137 bits (345), Expect = 3e-32
 Identities = 95/287 (33%), Positives = 141/287 (49%), Gaps = 28/287 (9%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE- 79
           G+I SPNYP  Y    E  W I V EG+ + L F   +IE  ++CAYD +++  G TEE 
Sbjct: 473 GQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEIERHDSCAYDYLEVRDGPTEES 532

Query: 80  ---GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECT 136
              G  CG            E+ +   N+L + F SD S  +   GFAA +   +++EC+
Sbjct: 533 ALIGHFCGYEKP--------EDVKSSSNRLWMKFVSDGSINK--AGFAANFF-KEVDECS 581

Query: 137 DFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPY 196
                 C H C N +G Y C+C P Y L  D K C V C G + T L G I SP +PK Y
Sbjct: 582 WPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFI-TKLNGTITSPGWPKEY 640

Query: 197 PENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGD-----RQFGPYC 251
           P N  C +Q+     ++  ++L+ E F++E  D    C    V V        +  G +C
Sbjct: 641 PTNKNCVWQVVAPAQYR--ISLQFEVFELEGNDV---CKYDFVEVRSGLSPDAKLHGRFC 695

Query: 252 GHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
           G   P    I ++SN + + F++D T  K+G++  +  D   C K++
Sbjct: 696 GSETPEV--ITSQSNNMRVEFKSDNTVSKRGFRAHFFSDKDECAKDN 740



 Score =  112 bits (279), Expect = 1e-24
 Identities = 76/268 (28%), Positives = 126/268 (47%), Gaps = 18/268 (6%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G I SP +P+ YP+     W +  P  Y I L F   ++E ++ C YD V++ SG + + 
Sbjct: 629 GTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFELEGNDVCKYDFVEVRSGLSPDA 688

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
           +L G+   +     I  +     N ++V FKSD +  +R  GF A++ + D +EC    +
Sbjct: 689 KLHGRFCGSETPEVITSQS----NNMRVEFKSDNTVSKR--GFRAHFFS-DKDECAKD-N 740

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
             C H C N  G Y C C   Y+LH++  +C         +++ G +ASPN+P  YP   
Sbjct: 741 GGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAHKISSVEGTLASPNWPDKYPSRR 800

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGP----YCGHGFP 256
            C + I    G +V +T    +F++E         D L    G     P    +CG   P
Sbjct: 801 ECTWNISSTAGHRVKLTF--NEFEIEQHQEC--AYDHLEMYDGPDSLAPILGRFCGSKKP 856

Query: 257 GPLNIETKSNALDIIFQTDLTGQKKGWK 284
            P       +++ + F +D + Q+KG++
Sbjct: 857 DP--TVASGSSMFLRFYSDASVQRKGFQ 882



 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 73/280 (26%), Positives = 111/280 (39%), Gaps = 57/280 (20%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G   +P +P  YPS     W I V  G  I L FT +D+  S  C YD V++  G   + 
Sbjct: 360 GNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGYWRKA 419

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
            L G+   +    P+V       ++L V F+S  S+     GF A Y AT          
Sbjct: 420 PLLGRFCGDKIPEPLVS----TDSRLWVEFRS--SSNILGKGFFAAYEAT---------- 463

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                         CG + + D      G+I SPNYP  Y  + 
Sbjct: 464 ------------------------------CGGDMNKDA-----GQIQSPNYPDDYRPSK 488

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQFGPYCGH--GFPGP 258
            C ++I + +GF V +T   + F++E  DS     D L    G  +     GH  G+  P
Sbjct: 489 ECVWRITVSEGFHVGLTF--QAFEIERHDSC--AYDYLEVRDGPTEESALIGHFCGYEKP 544

Query: 259 LNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
            ++++ SN L + F +D +  K G+   +  +   C   D
Sbjct: 545 EDVKSSSNRLWMKFVSDGSINKAGFAANFFKEVDECSWPD 584



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 67/269 (24%), Positives = 108/269 (40%), Gaps = 53/269 (19%)

Query: 21   GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
            G + SPN+P  YPS  E +W+I    G+ + L F   +IE  + CAYD +++  G     
Sbjct: 785  GTLASPNWPDKYPSRRECTWNISSTAGHRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLA 844

Query: 81   RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
             + G+   +    P V      + +    F SD S + +  GF A +             
Sbjct: 845  PILGRFCGSKKPDPTVASGSSMFLR----FYSDASVQRK--GFQAVHST----------- 887

Query: 141  VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                          CG     +V T  +   A       YP  +
Sbjct: 888  -----------------------------ECGGRLKAEVQTKELYSHAQFG-DNNYPSEA 917

Query: 201  RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSL-VFVAGDRQFGPYCGHGFPGPL 259
            RC++ I  E G+ V +T R  + + E AD   + +++   + +   + G +CG    GPL
Sbjct: 918  RCDWVIVAEDGYGVELTFRTFEVE-EEADCGYDYMEAYDGYDSSAPRLGRFCG---SGPL 973

Query: 260  -NIETKSNALDIIFQTDLTGQKKGWKLRY 287
              I +  ++L I F+TD T  KKG+  RY
Sbjct: 974  EEIYSAGDSLMIRFRTDDTINKKGFHARY 1002



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 14/107 (13%)

Query: 32   YPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE----GRLCGQRS 87
            YPSE    W I   +GYG+ L F   ++E   +C YD ++   G        GR CG   
Sbjct: 913  YPSEARCDWVIVAEDGYGVELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCG--- 969

Query: 88   SNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINE 134
                 S  +EE     + L + F++D +  ++  GF A Y +T   +
Sbjct: 970  -----SGPLEEIYSAGDSLMIRFRTDDTINKK--GFHARYTSTKFQD 1009



 Score = 30.8 bits (68), Expect = 4.4
 Identities = 12/46 (26%), Positives = 22/46 (47%)

Query: 177 GDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRRED 222
           G+      G  ++P +P  YP  S C ++I +  G ++V+     D
Sbjct: 352 GETLQDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMD 397


>gi|110578663 hypothetical protein LOC203074 [Homo sapiens]
          Length = 352

 Score =  132 bits (331), Expect = 1e-30
 Identities = 91/287 (31%), Positives = 138/287 (48%), Gaps = 42/287 (14%)

Query: 416 PELPKCVPVCGVPREPFEEK---QRIIGGSDADIKNFPWQVFFD---NPWAGGALINEYW 469
           P  P  V  CG  R  FE +    RI GG +A++  FPWQV       P+ GG+++N++W
Sbjct: 44  PHPPSPVSECG-DRSIFEGRTRYSRITGGMEAEVGEFPWQVSIQARSEPFCGGSILNKWW 102

Query: 470 VLTAAHVVEGNR----EPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTN 525
           +LTAAH +        E ++ +G+  + +  +   ++ +   + +H  +K       R N
Sbjct: 103 ILTAAHCLYSEELFPEELSVVLGTNDLTSPSMEIKEVAS---IILHKDFK-------RAN 152

Query: 526 FDNDIALVRLKDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR---AVRL 582
            DNDIAL+ L  P+K+     PICLP         +     ++GWG+T   D+      L
Sbjct: 153 MDNDIALLLLASPIKLDDLKVPICLPTQPGPATWRE---CWVAGWGQTNAADKNSVKTDL 209

Query: 583 KAARLPVAPLRKCKEVKVEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDP 641
             A + +    +C ++  +           T NM+CAG   +  D+CKGDSGG   V  P
Sbjct: 210 MKAPMVIMDWEECSKMFPK----------LTKNMLCAGYKNESYDACKGDSGGPL-VCTP 258

Query: 642 NDKTKFYAAGLVSWGPQCG---TYGLYTRVKNYVDWIMKTMQENSTP 685
               K+Y  G++SWG  CG   T G+YT + NY  WI K  Q    P
Sbjct: 259 EPGEKWYQVGIISWGKSCGEKNTPGIYTSLVNYNLWIEKVTQLEGRP 305


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score =  130 bits (328), Expect = 3e-30
 Identities = 79/258 (30%), Positives = 127/258 (49%), Gaps = 34/258 (13%)

Query: 430 EPFEEKQRIIGGSDADIKNFPWQVFFD---NPWAGGALINEYWVLTAAHVVEGNREPTMY 486
           + F +  R++GG DA    FPWQV  +   + + GG+++NE W++TAAH VE   + T+ 
Sbjct: 219 QSFNDFTRVVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVV 278

Query: 487 VGSTSVQTSRLAKSK----MLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMG 542
            G  +++ +   + K     + P H +                +++DIAL+ L +P+ + 
Sbjct: 279 AGEHNIEETEHTEQKRNVIRIIPHHNY----------NAAINKYNHDIALLELDEPLVLN 328

Query: 543 PTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVE 601
             V+PIC+         +    G +SGWGR   + R A+ L+  R+P+     C      
Sbjct: 329 SYVTPICIADKEYTNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLR---- 384

Query: 602 KPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC- 659
                +  +    NM CAG  E G DSC+GDSGG    +        +  G++SWG +C 
Sbjct: 385 -----STKFTIYNNMFCAGFHEGGRDSCQGDSGGPHVTEVEGTS---FLTGIISWGEECA 436

Query: 660 --GTYGLYTRVKNYVDWI 675
             G YG+YT+V  YV+WI
Sbjct: 437 MKGKYGIYTKVSRYVNWI 454


>gi|4506115 protein C [Homo sapiens]
          Length = 461

 Score =  130 bits (326), Expect = 5e-30
 Identities = 100/337 (29%), Positives = 158/337 (46%), Gaps = 66/337 (19%)

Query: 395 NGGGGEYHCAGNGSW------VNEVLGPELPKCVPV----CGVPREPFEEKQ-------- 436
           + GG  ++C     W          LG +L +C P     CG P +  E+K+        
Sbjct: 143 DNGGCTHYCLEEVGWRRCSCAPGYKLGDDLLQCHPAVKFPCGRPWKRMEKKRSHLKRDTE 202

Query: 437 --------RIIGGSDADIKNFPWQVFFDNPW----AGGALINEYWVLTAAHVVEGNREPT 484
                   R+I G      + PWQV   +       G  LI+  WVLTAAH ++ +++  
Sbjct: 203 DQEDQVDPRLIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLL 262

Query: 485 MYVGSTSVQTSRLAKSKM-LTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGP 543
           + +G   ++  R  K ++ L  + VF+HP +        ++  DNDIAL+ L  P  +  
Sbjct: 263 VRLGEYDLR--RWEKWELDLDIKEVFVHPNYS-------KSTTDNDIALLHLAQPATLSQ 313

Query: 544 TVSPICLP--GTSSDYNLMDGDLGLISGWG------RTEKRDRAVRLKAARLPVAPLRKC 595
           T+ PICLP  G +       G   L++GWG      +  KR+R   L   ++PV P  +C
Sbjct: 314 TIVPICLPDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNEC 373

Query: 596 KEVKVEKPTADAEAYVFTPNMICAG--GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLV 653
            EV          + + + NM+CAG  G++  D+C+GDSGG       +    ++  GLV
Sbjct: 374 SEVM---------SNMVSENMLCAGILGDR-QDACEGDSGGPMVA---SFHGTWFLVGLV 420

Query: 654 SWGPQCG---TYGLYTRVKNYVDWIMKTMQENSTPRE 687
           SWG  CG    YG+YT+V  Y+DWI   +++   P++
Sbjct: 421 SWGEGCGLLHNYGVYTKVSRYLDWIHGHIRDKEAPQK 457



 Score = 35.0 bits (79), Expect = 0.23
 Identities = 13/29 (44%), Positives = 17/29 (58%)

Query: 143 CSHFCNNFIGGYFCSCPPEYFLHDDMKNC 171
           C+H+C   +G   CSC P Y L DD+  C
Sbjct: 147 CTHYCLEEVGWRRCSCAPGYKLGDDLLQC 175


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score =  128 bits (322), Expect = 2e-29
 Identities = 92/288 (31%), Positives = 135/288 (46%), Gaps = 28/288 (9%)

Query: 20  YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
           YG I SPNYP  Y       W I+V EG+ + L F   +IE  ++CAYD +++  G +E 
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 80  ----GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINEC 135
               GR CG            ++ +   ++L + F SD S  +   GFA  +   +++EC
Sbjct: 503 STLIGRYCGYEKP--------DDIKSTSSRLWLKFVSDGSINK--AGFAVNFF-KEVDEC 551

Query: 136 TDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKP 195
           +      C   C N +G Y CSC P Y L  D + C   C G   T L G I SP +PK 
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGG-FLTKLNGSITSPGWPKE 610

Query: 196 YPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFV-----AGDRQFGPY 250
           YP N  C +Q  L    Q  ++L+ + F+ E  D    C    V V     A  +  G +
Sbjct: 611 YPPNKNCIWQ--LVAPTQYRISLQFDFFETEGNDV---CKYDFVEVRSGLTADSKLHGKF 665

Query: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
           CG     P  I ++ N + + F++D T  KKG+K  +  D   C K++
Sbjct: 666 CGS--EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDN 711



 Score =  109 bits (273), Expect = 7e-24
 Identities = 78/267 (29%), Positives = 126/267 (47%), Gaps = 16/267 (5%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G I SP +P+ YP      W +  P  Y I L F   + E ++ C YD V++ SG T + 
Sbjct: 600 GSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADS 659

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
           +L G+   +     I  +    YN ++V FKSD +  ++  GF A++ + D +EC+   +
Sbjct: 660 KLHGKFCGSEKPEVITSQ----YNNMRVEFKSDNTVSKK--GFKAHFFS-DKDECSKD-N 711

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
             C   C N  G Y C C   + LHD+  +C         T+  G I SPN+P  YP   
Sbjct: 712 GGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKK 771

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ---FGPYCGHGFPG 257
            C + I    G +V +T    D + +  + A + L+  VF   D +    G +CG   P 
Sbjct: 772 ECTWAISSTPGHRVKLTFMEMDIESQ-PECAYDHLE--VFDGRDAKAPVLGRFCGSKKPE 828

Query: 258 PLNIETKSNALDIIFQTDLTGQKKGWK 284
           P  +    + + + F +D + Q+KG++
Sbjct: 829 P--VLATGSRMFLRFYSDNSVQRKGFQ 853



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 75/280 (26%), Positives = 111/280 (39%), Gaps = 61/280 (21%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G   SP YP  Y + +   W I V  G  I L FT LD+  S  C YD V++  G   + 
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
            L G+   +    PIV       ++L V F+S  S+     GF A Y A           
Sbjct: 391 PLRGRFCGSKLPEPIVS----TDSRLWVEFRS--SSNWVGKGFFAVYEAI---------- 434

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                             C GDV     G I SPNYP  Y  + 
Sbjct: 435 ----------------------------------CGGDV-KKDYGHIQSPNYPDDYRPSK 459

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ----FGPYCGHGFP 256
            C ++I++ +GF V +T   + F++E  DS     D L    G  +     G YC  G+ 
Sbjct: 460 VCIWRIQVSEGFHVGLTF--QSFEIERHDSC--AYDYLEVRDGHSESSTLIGRYC--GYE 513

Query: 257 GPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPK 296
            P +I++ S+ L + F +D +  K G+ + +  +   C +
Sbjct: 514 KPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 66/269 (24%), Positives = 106/269 (39%), Gaps = 53/269 (19%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G I SPN+P  YPS+ E +W I    G+ + L F  +DIE    CAYD +++  G   + 
Sbjct: 756 GTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKA 815

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
            + G+   +    P++       +++ + F SD S + +  GF A +             
Sbjct: 816 PVLGRFCGSKKPEPVL----ATGSRMFLRFYSDNSVQRK--GFQASHAT----------- 858

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                         CG     DV T  +   A       YP   
Sbjct: 859 -----------------------------ECGGQVRADVKTKDLYSHAQFG-DNNYPGGV 888

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLV--FVAGDRQFGPYCGHGFPGP 258
            CE+ I  E+G+ V +    + F+VE     G     L   + +   + G YCG G   P
Sbjct: 889 DCEWVIVAEEGYGVELVF--QTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSG--PP 944

Query: 259 LNIETKSNALDIIFQTDLTGQKKGWKLRY 287
             + +  +++ + F +D T  KKG+ LRY
Sbjct: 945 EEVYSAGDSVLVKFHSDDTITKKGFHLRY 973



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 6/103 (5%)

Query: 32  YPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEGRLCGQRSSNNP 91
           YP  V+  W I   EGYG+ L F   ++E   +C YD +++  G        G+   + P
Sbjct: 884 YPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGP 943

Query: 92  HSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINE 134
                EE     + + V F SD +  ++  GF   Y +T   +
Sbjct: 944 ----PEEVYSAGDSVLVKFHSDDTITKK--GFHLRYTSTKFQD 980


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  128 bits (321), Expect = 2e-29
 Identities = 89/269 (33%), Positives = 131/269 (48%), Gaps = 23/269 (8%)

Query: 425 CGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWA---GGALINEYWVLTAAHVV-EGN 480
           CG  + P +   RI+GG D  +  +PWQV      A   GG+L++  WVLTAAH   E N
Sbjct: 153 CGRRKLPVD---RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209

Query: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540
           R  + +                L  + V  H G+     P    N  NDIALV L  P+ 
Sbjct: 210 RVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLP 268

Query: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKR-DRAVRLKAARLPVAPLRKCKEVK 599
           +   + P+CLP       L+DG +  ++GWG T+    +A  L+ AR+P+     C    
Sbjct: 269 LTEYIQPVCLPAAGQA--LVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG-- 324

Query: 600 VEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKT-KFYAAGLVSWGP 657
                AD       P M CAG  E G+D+C+GDSGG F  +D   +T ++   G+VSWG 
Sbjct: 325 -----ADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT 379

Query: 658 QCGTY---GLYTRVKNYVDWIMKTMQENS 683
            C      G+YT+V ++ +WI + ++ +S
Sbjct: 380 GCALAQKPGVYTKVSDFREWIFQAIKTHS 408


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  128 bits (321), Expect = 2e-29
 Identities = 89/269 (33%), Positives = 131/269 (48%), Gaps = 23/269 (8%)

Query: 425 CGVPREPFEEKQRIIGGSDADIKNFPWQVFFDNPWA---GGALINEYWVLTAAHVV-EGN 480
           CG  + P +   RI+GG D  +  +PWQV      A   GG+L++  WVLTAAH   E N
Sbjct: 153 CGRRKLPVD---RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERN 209

Query: 481 REPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVK 540
           R  + +                L  + V  H G+     P    N  NDIALV L  P+ 
Sbjct: 210 RVLSRWRVFAGAVAQASPHGLQLGVQAVVYHGGYLPFRDPNSEEN-SNDIALVHLSSPLP 268

Query: 541 MGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKR-DRAVRLKAARLPVAPLRKCKEVK 599
           +   + P+CLP       L+DG +  ++GWG T+    +A  L+ AR+P+     C    
Sbjct: 269 LTEYIQPVCLPAAGQA--LVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNG-- 324

Query: 600 VEKPTADAEAYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKT-KFYAAGLVSWGP 657
                AD       P M CAG  E G+D+C+GDSGG F  +D   +T ++   G+VSWG 
Sbjct: 325 -----ADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT 379

Query: 658 QCGTY---GLYTRVKNYVDWIMKTMQENS 683
            C      G+YT+V ++ +WI + ++ +S
Sbjct: 380 GCALAQKPGVYTKVSDFREWIFQAIKTHS 408


>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score =  126 bits (316), Expect = 8e-29
 Identities = 91/274 (33%), Positives = 135/274 (49%), Gaps = 46/274 (16%)

Query: 437 RIIGGSDADIKNFPWQV--FFDNPW---AGGALINEYWVLTAAHVV------EGNREPTM 485
           RI+ GSDA+I   PWQV  F  +P     G +LI++ WVLTAAH +      +   E  +
Sbjct: 363 RIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDL 422

Query: 486 YVGSTSVQTSRLAKS--KMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGP 543
            V       +R  ++  K+   E ++IHP +        R N D DIAL++LK PV    
Sbjct: 423 LVRIGKHSRTRYERNIEKISMLEKIYIHPRYNW------RENLDRDIALMKLKKPVAFSD 476

Query: 544 TVSPICLPGTSSDYNLMD-GDLGLISGWGRTEK-------RDRAVRLKAARLPVAPLRKC 595
            + P+CLP   +  +L+  G  G ++GWG  ++       + +   L+   LP+     C
Sbjct: 477 YIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVERPVC 536

Query: 596 KEVKVEKPTADAEAYVFTPNMICAG-----GEKGMDSCKGDSGGAFAVQDPNDKTKFYAA 650
           K         D+     T NM CAG     G++G D+C+GDSGG F ++ P +  ++Y  
Sbjct: 537 K---------DSTRIRITDNMFCAGYKPDEGKRG-DACEGDSGGPFVMKSPFN-NRWYQM 585

Query: 651 GLVSWGPQC---GTYGLYTRVKNYVDWIMKTMQE 681
           G+VSWG  C   G YG YT V     WI K + +
Sbjct: 586 GIVSWGEGCDRDGKYGFYTHVFRLKKWIQKVIDQ 619


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score =  126 bits (316), Expect = 8e-29
 Identities = 90/289 (31%), Positives = 137/289 (47%), Gaps = 32/289 (11%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE- 79
           G+I SPNYP  Y    E  W I V E Y + L F   +IE  +NCAYD +++  G +E  
Sbjct: 471 GQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEIERHDNCAYDYLEVRDGTSENS 530

Query: 80  ---GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECT 136
              GR CG            E+ +   N L + F SD +  +   GFAA +   + +EC 
Sbjct: 531 PLIGRFCGYDKP--------EDIRSTSNTLWMKFVSDGTVNK--AGFAANFFKEE-DECA 579

Query: 137 DFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPY 196
                 C   C N +G Y C+C P Y L  D ++C   C G + T L G I +P +PK Y
Sbjct: 580 KPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGG-LLTKLNGTITTPGWPKEY 638

Query: 197 PENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFV-------AGDRQFGP 249
           P N  C +Q+     ++  ++++ E F++E     GN +    +V       +  +  G 
Sbjct: 639 PPNKNCVWQVVAPTQYR--ISVKFEFFELE-----GNEVCKYDYVEIWSGLSSESKLHGK 691

Query: 250 YCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
           +CG   P    I ++ N + I F++D T  KKG+K  +  D   C K++
Sbjct: 692 FCGAEVPEV--ITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDN 738



 Score =  112 bits (280), Expect = 1e-24
 Identities = 78/269 (28%), Positives = 127/269 (47%), Gaps = 20/269 (7%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G I +P +P+ YP      W +  P  Y I + F   ++E +E C YD V+I SG + E 
Sbjct: 627 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSES 686

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
           +L G+         I  +F    N +++ FKSD +  ++  GF A++ + D +EC+   +
Sbjct: 687 KLHGKFCGAEVPEVITSQF----NNMRIEFKSDNTVSKK--GFKAHFFS-DKDECSKD-N 738

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNC-GVNCSGDVFTALIGEIASPNYPKPYPEN 199
             C H C N +G Y C C   + LHD+  +C    C   + +   G I SPN+P  YP  
Sbjct: 739 GGCQHECVNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSP-SGLITSPNWPDKYPSR 797

Query: 200 SRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ----FGPYCGHGF 255
             C ++I    G +  + L   +F++E         D L    G+ +     G  CG+  
Sbjct: 798 KECTWEISATPGHR--IKLAFSEFEIEQHQEC--AYDHLEVFDGETEKSPILGRLCGNKI 853

Query: 256 PGPLNIETKSNALDIIFQTDLTGQKKGWK 284
           P PL      N + + F +D + Q+KG++
Sbjct: 854 PDPL--VATGNKMFVRFVSDASVQRKGFQ 880



 Score = 79.3 bits (194), Expect = 1e-14
 Identities = 76/271 (28%), Positives = 113/271 (41%), Gaps = 57/271 (21%)

Query: 21   GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
            G I SPN+P  YPS  E +W+I    G+ I L F+  +IE  + CAYD +++  G+TE+ 
Sbjct: 783  GLITSPNWPDKYPSRKECTWEISATPGHRIKLAFSEFEIEQHQECAYDHLEVFDGETEKS 842

Query: 81   RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
             + G+   N    P+V       NK+ V F SD S + +  GF     AT   EC   + 
Sbjct: 843  PILGRLCGNKIPDPLV----ATGNKMFVRFVSDASVQRK--GFQ----ATHSTECGGRLK 892

Query: 141  VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                            S P + + H           GD                 YP   
Sbjct: 893  AE--------------SKPRDLYSHAQF--------GD---------------NNYPGQV 915

Query: 201  RCEYQIRLEKGFQVVVTLRREDFDVEAADSAG----NCLDSLVFVAGDRQFGPYCGHGFP 256
             CE+ +  E+G ++ ++   + F+VE     G       D L   A     G +CG G  
Sbjct: 916  DCEWLLVSERGSRLELSF--QTFEVEEEADCGYDYVELFDGLDSTAVG--LGRFCGSG-- 969

Query: 257  GPLNIETKSNALDIIFQTDLTGQKKGWKLRY 287
             P  I +  +++ I F TD T  KKG+ +RY
Sbjct: 970  PPEEIYSIGDSVLIHFHTDDTINKKGFHIRY 1000



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 72/285 (25%), Positives = 110/285 (38%), Gaps = 67/285 (23%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE- 79
           G + SP +P  YPS     W + V  G  I L FT +D+  S  C YD +++  G   + 
Sbjct: 358 GNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGYWRKS 417

Query: 80  ---GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECT 136
              GR CG +        + E      +++ + F+S  S+     GFAA Y A       
Sbjct: 418 PLLGRFCGDK--------LPEVLTSTDSRMWIEFRS--SSNWVGKGFAAVYEAI------ 461

Query: 137 DFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPY 196
                                                 C G++     G+I SPNYP  Y
Sbjct: 462 --------------------------------------CGGEI-RKNEGQIQSPNYPDDY 482

Query: 197 PENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNC-LDSLVFVAGDRQFGPYCGH-- 253
                C ++I + + + V +T   + F++E  D   NC  D L    G  +  P  G   
Sbjct: 483 RPMKECVWKITVSESYHVGLTF--QSFEIERHD---NCAYDYLEVRDGTSENSPLIGRFC 537

Query: 254 GFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPKED 298
           G+  P +I + SN L + F +D T  K G+   +  +   C K D
Sbjct: 538 GYDKPEDIRSTSNTLWMKFVSDGTVNKAGFAANFFKEEDECAKPD 582



 Score = 30.0 bits (66), Expect = 7.5
 Identities = 11/46 (23%), Positives = 23/46 (50%)

Query: 177 GDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRRED 222
           G+      G ++SP +P  YP  + C +++ +  G ++V+     D
Sbjct: 350 GETLQESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMD 395


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  126 bits (316), Expect = 8e-29
 Identities = 80/249 (32%), Positives = 126/249 (50%), Gaps = 28/249 (11%)

Query: 435 KQRIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 491
           +QRI+GG++A+  ++PWQV     +    GG+LIN  W+LTAAH    N  P  ++ ++ 
Sbjct: 184 EQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIATSG 243

Query: 492 VQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 551
           + T+   K +M    ++ IH  +K           +NDIALVRL++ V     +  +CLP
Sbjct: 244 ISTT-FPKLRMRV-RNILIHNNYK-------SATHENDIALVRLENSVTFTKDIHSVCLP 294

Query: 552 GTSSDYNLMDGDLGLISGWGRTEKRDRAV-RLKAARLPVAPLRKCKEVKVEKPTADAEAY 610
             +   N+  G    ++GWG  E     V  L+  ++ +     C           +   
Sbjct: 295 AATQ--NIPPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCN-------APHSYNG 345

Query: 611 VFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCG---TYGLYT 666
                M+CAG  + G+D+C+GDSGG    +D   +  ++  G+VSWG QCG     G+YT
Sbjct: 346 AILSGMLCAGVPQGGVDACQGDSGGPLVQED--SRRLWFIVGIVSWGDQCGLPDKPGVYT 403

Query: 667 RVKNYVDWI 675
           RV  Y+DWI
Sbjct: 404 RVTAYLDWI 412


>gi|4503625 coagulation factor X preproprotein [Homo sapiens]
          Length = 488

 Score =  125 bits (315), Expect = 1e-28
 Identities = 81/260 (31%), Positives = 132/260 (50%), Gaps = 30/260 (11%)

Query: 437 RIIGGSDADIKNFPWQVFFDNP----WAGGALINEYWVLTAAHVVEGNREPTMYVGSTSV 492
           RI+GG +      PWQ    N     + GG +++E+++LTAAH +   +   + VG  + 
Sbjct: 234 RIVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNT 293

Query: 493 QTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLPG 552
           +     ++ +   E V  H  +        +  +D DIA++RLK P+     V+P CLP 
Sbjct: 294 EQEEGGEA-VHEVEVVIKHNRFT-------KETYDFDIAVLRLKTPITFRMNVAPACLPE 345

Query: 553 TS-SDYNLMDGDLGLISGWGRT-EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADAEAY 610
              ++  LM    G++SG+GRT EK  ++ RLK   +P      CK          + ++
Sbjct: 346 RDWAESTLMTQKTGIVSGFGRTHEKGRQSTRLKMLEVPYVDRNSCKL---------SSSF 396

Query: 611 VFTPNMICAGGE-KGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC---GTYGLYT 666
           + T NM CAG + K  D+C+GDSGG    +    K  ++  G+VSWG  C   G YG+YT
Sbjct: 397 IITQNMFCAGYDTKQEDACQGDSGGPHVTR---FKDTYFVTGIVSWGEGCARKGKYGIYT 453

Query: 667 RVKNYVDWIMKTMQENSTPR 686
           +V  ++ WI ++M+    P+
Sbjct: 454 KVTAFLKWIDRSMKTRGLPK 473


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
           sapiens]
          Length = 730

 Score =  124 bits (312), Expect = 2e-28
 Identities = 90/283 (31%), Positives = 132/283 (46%), Gaps = 28/283 (9%)

Query: 20  YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
           YG I SPNYP  Y       W I+V EG+ + L F   +IE  ++CAYD +++  G +E 
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 80  ----GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINEC 135
               GR CG            ++ +   ++L + F SD S  +   GFA  +   +++EC
Sbjct: 503 STLIGRYCGYEKP--------DDIKSTSSRLWLKFVSDGSINK--AGFAVNFF-KEVDEC 551

Query: 136 TDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKP 195
           +      C   C N +G Y CSC P Y L  D + C   C G   T L G I SP +PK 
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGG-FLTKLNGSITSPGWPKE 610

Query: 196 YPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFV-----AGDRQFGPY 250
           YP N  C +Q  L    Q  ++L+ + F+ E  D    C    V V     A  +  G +
Sbjct: 611 YPPNKNCIWQ--LVAPTQYRISLQFDFFETEGNDV---CKYDFVEVRSGLTADSKLHGKF 665

Query: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMP 293
           CG     P  I ++ N + + F++D T  KKG+K  +  +  P
Sbjct: 666 CGS--EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRP 706



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 75/280 (26%), Positives = 111/280 (39%), Gaps = 61/280 (21%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G   SP YP  Y + +   W I V  G  I L FT LD+  S  C YD V++  G   + 
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
            L G+   +    PIV       ++L V F+S  S+     GF A Y A           
Sbjct: 391 PLRGRFCGSKLPEPIVS----TDSRLWVEFRS--SSNWVGKGFFAVYEAI---------- 434

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                             C GDV     G I SPNYP  Y  + 
Sbjct: 435 ----------------------------------CGGDV-KKDYGHIQSPNYPDDYRPSK 459

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ----FGPYCGHGFP 256
            C ++I++ +GF V +T   + F++E  DS     D L    G  +     G YC  G+ 
Sbjct: 460 VCIWRIQVSEGFHVGLTF--QSFEIERHDSC--AYDYLEVRDGHSESSTLIGRYC--GYE 513

Query: 257 GPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPK 296
            P +I++ S+ L + F +D +  K G+ + +  +   C +
Sbjct: 514 KPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
           sapiens]
          Length = 823

 Score =  122 bits (306), Expect = 1e-27
 Identities = 89/277 (32%), Positives = 130/277 (46%), Gaps = 28/277 (10%)

Query: 20  YGEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE 79
           YG I SPNYP  Y       W I+V EG+ + L F   +IE  ++CAYD +++  G +E 
Sbjct: 443 YGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSES 502

Query: 80  ----GRLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINEC 135
               GR CG            ++ +   ++L + F SD S  +   GFA  +   +++EC
Sbjct: 503 STLIGRYCGYEKP--------DDIKSTSSRLWLKFVSDGSINK--AGFAVNFF-KEVDEC 551

Query: 136 TDFVDVPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKP 195
           +      C   C N +G Y CSC P Y L  D + C   C G   T L G I SP +PK 
Sbjct: 552 SRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGG-FLTKLNGSITSPGWPKE 610

Query: 196 YPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFV-----AGDRQFGPY 250
           YP N  C +Q  L    Q  ++L+ + F+ E  D    C    V V     A  +  G +
Sbjct: 611 YPPNKNCIWQ--LVAPTQYRISLQFDFFETEGNDV---CKYDFVEVRSGLTADSKLHGKF 665

Query: 251 CGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRY 287
           CG     P  I ++ N + + F++D T  KKG+K  +
Sbjct: 666 CGS--EKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF 700



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 75/280 (26%), Positives = 111/280 (39%), Gaps = 61/280 (21%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEEG 80
           G   SP YP  Y + +   W I V  G  I L FT LD+  S  C YD V++  G   + 
Sbjct: 331 GNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKA 390

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYYVATDINECTDFVD 140
            L G+   +    PIV       ++L V F+S  S+     GF A Y A           
Sbjct: 391 PLRGRFCGSKLPEPIVS----TDSRLWVEFRS--SSNWVGKGFFAVYEAI---------- 434

Query: 141 VPCSHFCNNFIGGYFCSCPPEYFLHDDMKNCGVNCSGDVFTALIGEIASPNYPKPYPENS 200
                                             C GDV     G I SPNYP  Y  + 
Sbjct: 435 ----------------------------------CGGDV-KKDYGHIQSPNYPDDYRPSK 459

Query: 201 RCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCLDSLVFVAGDRQ----FGPYCGHGFP 256
            C ++I++ +GF V +T   + F++E  DS     D L    G  +     G YC  G+ 
Sbjct: 460 VCIWRIQVSEGFHVGLTF--QSFEIERHDSC--AYDYLEVRDGHSESSTLIGRYC--GYE 513

Query: 257 GPLNIETKSNALDIIFQTDLTGQKKGWKLRYHGDPMPCPK 296
            P +I++ S+ L + F +D +  K G+ + +  +   C +
Sbjct: 514 KPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR 553


>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
          Length = 268

 Score =  117 bits (294), Expect = 3e-26
 Identities = 85/274 (31%), Positives = 128/274 (46%), Gaps = 33/274 (12%)

Query: 421 CVPVCGVPREPFEEKQRIIGGSDADIKNFPWQVFF----DNPW---AGGALINEYWVLTA 473
           C   CGVP  P     R++GG DA   ++PWQ+      ++ W    GG LI   +VLTA
Sbjct: 13  CASSCGVPSFPPNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTA 72

Query: 474 AHVVEGNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALV 533
           AH +   R   + VG  +++      S  +  + + +H  W  L +        NDIAL+
Sbjct: 73  AHCISNTRTYRVAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNALLL-------RNDIALI 125

Query: 534 RLKDPVKMGPTVSPICLPGTSSDYNLMDGDLG-LISGWGRT-EKRDRAVRLKAARLPVAP 591
           +L + V++  T+   CLP   S   L+  D    ++GWGR       A +L+    PV  
Sbjct: 126 KLAEHVELSDTIQVACLPEKDS---LLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVD 182

Query: 592 LRKCKEVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAG 651
              C  +       D   +     M+CAGG+  + +C GDSGG    Q  N   + +  G
Sbjct: 183 HATCSRI-------DWWGFRVKKTMVCAGGDGVISACNGDSGGPLNCQLENGSWEVF--G 233

Query: 652 LVSWGPQ--CGTYG---LYTRVKNYVDWIMKTMQ 680
           +VS+G +  C T     +YTRV  Y+DWI + MQ
Sbjct: 234 IVSFGSRRGCNTRKKPVVYTRVSAYIDWINEKMQ 267


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  117 bits (294), Expect = 3e-26
 Identities = 90/269 (33%), Positives = 125/269 (46%), Gaps = 35/269 (13%)

Query: 425 CGVP--REPFEEKQRIIGGSDADIKNFPWQVFFDNP----WAGGALINEYWVLTAAHVVE 478
           CGVP          RI+ G DA   ++PWQV   +     + GG+LI+E WV+TAAH   
Sbjct: 19  CGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC-- 76

Query: 479 GNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDP 538
           G R   + V     Q S     ++L    VF +P + +L V       +NDI L++L  P
Sbjct: 77  GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV-------NNDITLLKLATP 129

Query: 539 VKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAV--RLKAARLPVAPLRKCK 596
            +   TVS +CLP    D+    G L   +GWG+T+        +L+ A LP+    +CK
Sbjct: 130 ARFSQTVSAVCLPSADDDFPA--GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECK 187

Query: 597 EVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWG 656
           +    +          T  MICAG   G+ SC GDSGG    Q     T     G+VSWG
Sbjct: 188 KSWGRR---------ITDVMICAGA-SGVSSCMGDSGGPLVCQKDGAWT---LVGIVSWG 234

Query: 657 PQ-CGTY--GLYTRVKNYVDWIMKTMQEN 682
              C T   G+Y RV   + W+ K +  N
Sbjct: 235 SDTCSTSSPGVYARVTKLIPWVQKILAAN 263


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  117 bits (293), Expect = 4e-26
 Identities = 139/549 (25%), Positives = 217/549 (39%), Gaps = 85/549 (15%)

Query: 174 NCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGN 233
           +C G +  A  G   SP YP  YP N  C + I +     V V  +   + +E    AG 
Sbjct: 339 SCGGRLRKAQ-GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFF-YLLEPGVPAGT 396

Query: 234 CLDSLVFVAGDRQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRY----HG 289
           C    V + G++    YCG        + + SN + + F +D +    G+   Y      
Sbjct: 397 CPKDYVEINGEK----YCGER--SQFVVTSNSNKITVRFHSDQSYTDTGFLAEYLSYDSS 450

Query: 290 DPMP---------CPKEDTPNSVWEPAKAKYVFRDVVQITCLDGFEVVEGRVGATSFYST 340
           DP P         C +++     W          D +  +C  G +           +  
Sbjct: 451 DPCPGQFTCRTGRCIRKELRCDGWADCTDH---SDELNCSCDAGHQFTCKNKFCKPLFWV 507

Query: 341 CQS-NGKWSNSK----------LKCQPVDCGIPESIENGKVEDPESTLFGSVIRY---TC 386
           C S N    NS            +C    C       NGK +  + +   S  +    TC
Sbjct: 508 CDSVNDCGDNSDEQGCSCPAQTFRCSNGKCLSKSQQCNGKDDCGDGSDEASCPKVNVVTC 567

Query: 387 EEPYYYMENG---GGGEYHCAGNGSWVNEVLGPELPKCVPVCGVPREPFEEKQRIIGGSD 443
            +  Y   NG     G   C G     +   G +   C   CG+    F  + R++GG+D
Sbjct: 568 TKHTYRCLNGLCLSKGNPECDGKEDCSD---GSDEKDCD--CGL--RSFTRQARVVGGTD 620

Query: 444 ADIKNFPWQVFF----DNPWAGGALINEYWVLTAAHVVEGNR-----EPTMYVGSTSV-- 492
           AD   +PWQV           G +LI+  W+++AAH    +R     +PT +     +  
Sbjct: 621 ADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTAFLGLHD 680

Query: 493 QTSRLAKS-KMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPICLP 551
           Q+ R A   +    + +  HP +           FD DIAL+ L+ P +    V PICLP
Sbjct: 681 QSQRSAPGVQERRLKRIISHPFFNDF-------TFDYDIALLELEKPAEYSSMVRPICLP 733

Query: 552 GTSSDYNLMDGDLGLISGWGRTEKRDR-AVRLKAARLPVAPLRKCKEVKVEKPTADAEAY 610
             S  +    G    ++GWG T+     A+ L+   + V     C+ +  ++        
Sbjct: 734 DASHVFPA--GKAIWVTGWGHTQYGGTGALILQKGEIRVINQTTCENLLPQQ-------- 783

Query: 611 VFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQCGTY---GLYT 666
             TP M+C G    G+DSC+GDSGG  +  + +   + + AG+VSWG  C      G+YT
Sbjct: 784 -ITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADG--RIFQAGVVSWGDGCAQRNKPGVYT 840

Query: 667 RVKNYVDWI 675
           R+  + DWI
Sbjct: 841 RLPLFRDWI 849



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 49/186 (26%)

Query: 21  GEILSPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDI----ELSENCAYDSVQIISGD 76
           G   SP YP  YP  ++ +W+IEVP    + + F    +      +  C  D V+ I+G+
Sbjct: 349 GTFNSPYYPGHYPPNIDCTWNIEVPNNQHVKVRFKFFYLLEPGVPAGTCPKDYVE-INGE 407

Query: 77  TEEGRLCGQRSSNNPHSPIVEEFQVP--YNKLQVIFKSDFSNEERFTGFAAYYVATDIN- 133
               + CG+RS          +F V    NK+ V F SD S  +  TGF A Y++ D + 
Sbjct: 408 ----KYCGERS----------QFVVTSNSNKITVRFHSDQSYTD--TGFLAEYLSYDSSD 451

Query: 134 ------------------------ECTDFVD-VPCSHFCNNFIGGYFCSCPPEYFLHDDM 168
                                   +CTD  D + CS    +        C P +++ D +
Sbjct: 452 PCPGQFTCRTGRCIRKELRCDGWADCTDHSDELNCSCDAGHQFTCKNKFCKPLFWVCDSV 511

Query: 169 KNCGVN 174
            +CG N
Sbjct: 512 NDCGDN 517



 Score = 30.4 bits (67), Expect = 5.7
 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 3/48 (6%)

Query: 189 SPNYP-KPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSAGNCL 235
           +P +P  PYP ++RC++ +R +    + +T R   FD+ + D  G+ L
Sbjct: 230 TPGFPDSPYPAHARCQWALRGDADSVLSLTFR--SFDLASCDERGSDL 275


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  117 bits (293), Expect = 4e-26
 Identities = 87/268 (32%), Positives = 129/268 (48%), Gaps = 36/268 (13%)

Query: 424 VCGVPREPFEEK---QRIIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVV 477
           VCG+P  PF  +   +RI GG +A    +PWQV   F  +   GGA+IN  W+LTAAH V
Sbjct: 560 VCGIP--PFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCV 617

Query: 478 EGNREPTMYVGSTSVQTSRLAKS--KMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRL 535
           +    P  +          L +S  ++   +H+ +H  +  L       ++D+DIAL++L
Sbjct: 618 QLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTL-------SYDSDIALIQL 670

Query: 536 KDPVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGR-TEKRDRAVRLKAARLPVAPLRK 594
             P++    V P+CLP ++    L   ++  ++GWG  +     A RL+  ++ V     
Sbjct: 671 SSPLEYNSVVRPVCLPHSAEP--LFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREV 728

Query: 595 CKEVKVEKPTADAEAYVFTPNMICAG----GEKGMDSCKGDSGGAFAVQDPNDKTKFYAA 650
           C     E     A     T  MICAG    GEK  D C+GDSGG    +  N     Y  
Sbjct: 729 C-----EHTYYSAHPGGITEKMICAGFAASGEK--DFCQGDSGGPLVCRHENGPFVLY-- 779

Query: 651 GLVSWGPQC---GTYGLYTRVKNYVDWI 675
           G+VSWG  C      G++ RV  ++DWI
Sbjct: 780 GIVSWGAGCVQPWKPGVFARVMIFLDWI 807



 Score = 89.0 bits (219), Expect = 1e-17
 Identities = 78/265 (29%), Positives = 115/265 (43%), Gaps = 37/265 (13%)

Query: 437 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMY-VGSTSV 492
           RI    ++ +   PWQV     ++ + GG+LI E  V+TAAH ++   E  +  +  TS 
Sbjct: 46  RISSWRNSTVTGHPWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSG 105

Query: 493 QTSRLAKSKM---LTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 549
           + S   K K    +    +  HP +        R     DIAL+ LK  VK G  V PIC
Sbjct: 106 EYSLFQKDKQEQNIPVSKIITHPEYN------SREYMSPDIALLYLKHKVKFGNAVQPIC 159

Query: 550 LPGTSSDYNLMDGDLGLISGWGRTEKRDRAVR-LKAARLPVAPLRKCKEVKVEKPTADAE 608
           LP   SD  +  G L L SGWG+  K       L+   LP+   R C  V          
Sbjct: 160 LP--DSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTV-----LKSMN 212

Query: 609 AYVFTPNMICAG-GEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQC-------- 659
                  M+CAG  + GMD+C+GDSGG    +       +  AG+ SW   C        
Sbjct: 213 LPPLGRTMLCAGFPDWGMDACQGDSGGPLVCR--RGGGIWILAGITSWVAGCAGGSVPVR 270

Query: 660 -----GTYGLYTRVKNYVDWIMKTM 679
                 + G++++V   +D+I + +
Sbjct: 271 NNHVKASLGIFSKVSELMDFITQNL 295



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 38/107 (35%), Positives = 49/107 (45%), Gaps = 15/107 (14%)

Query: 25  SPNYPQAYPSEVEKSWDIEVPEGYGIHLYFTHLDIELSENCAYDSVQIISGDTEE----G 80
           S  YP  YPS     W I  PE + I L F    ++ S NC YD+V +I GD+EE     
Sbjct: 433 SAKYPDLYPSNTRCHWFICAPEKHIIKLTFEDFAVKFSPNCIYDAV-VIYGDSEEKHKLA 491

Query: 81  RLCGQRSSNNPHSPIVEEFQVPYNKLQVIFKSDFSNEERFTGFAAYY 127
           +LCG  +  +  S          N   + FKSD  N  R  GF A +
Sbjct: 492 KLCGMLTITSIFS--------SSNMTVIYFKSDGKN--RLQGFKARF 528



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 11/120 (9%)

Query: 172 GVNCSGDVFTALIGEIASPNYPKPYPENSRCEYQIRLEKGFQVVVTLRREDFDVEAADSA 231
           G  C         G   S  YP  YP N+RC + I   +  + ++ L  EDF V+ +   
Sbjct: 416 GSGCGSLAILVEEGTNHSAKYPDLYPSNTRCHWFICAPE--KHIIKLTFEDFAVKFSP-- 471

Query: 232 GNCLDSLVFVAGD----RQFGPYCGHGFPGPLNIETKSNALDIIFQTDLTGQKKGWKLRY 287
            NC+   V + GD     +    C  G     +I + SN   I F++D   + +G+K R+
Sbjct: 472 -NCIYDAVVIYGDSEEKHKLAKLC--GMLTITSIFSSSNMTVIYFKSDGKNRLQGFKARF 528


>gi|118498350 chymotrypsin B2 [Homo sapiens]
          Length = 263

 Score =  115 bits (289), Expect = 1e-25
 Identities = 89/269 (33%), Positives = 125/269 (46%), Gaps = 35/269 (13%)

Query: 425 CGVP--REPFEEKQRIIGGSDADIKNFPWQVFFDNP----WAGGALINEYWVLTAAHVVE 478
           CGVP          RI+ G DA   ++PWQV   +     + GG+LI+E WV+TAAH   
Sbjct: 19  CGVPAIHPVLSGLSRIVNGEDAVPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHC-- 76

Query: 479 GNREPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWKLLEVPEGRTNFDNDIALVRLKDP 538
           G R   + V     Q S     ++L    VF +P + +L V       +NDI L++L  P
Sbjct: 77  GVRTSDVVVAGEFDQGSDEENIQVLKIAKVFKNPKFSILTV-------NNDITLLKLATP 129

Query: 539 VKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRTEKRDRAV--RLKAARLPVAPLRKCK 596
            +   TVS +CLP    D+    G L   +GWG+T+        +L+ A LP+    +CK
Sbjct: 130 ARFSQTVSAVCLPSADDDFPA--GTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECK 187

Query: 597 EVKVEKPTADAEAYVFTPNMICAGGEKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWG 656
           +    +          T  MICAG   G+ SC GDSGG    Q     T     G+VSWG
Sbjct: 188 KSWGRR---------ITDVMICAGA-SGVSSCMGDSGGPLVCQKDGAWT---LVGIVSWG 234

Query: 657 PQ-CGTY--GLYTRVKNYVDWIMKTMQEN 682
            + C T    +Y RV   + W+ K +  N
Sbjct: 235 SRTCSTTTPAVYARVAKLIPWVQKILAAN 263


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.138    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,733,952
Number of Sequences: 37866
Number of extensions: 1527592
Number of successful extensions: 5247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 208
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 3181
Number of HSP's gapped (non-prelim): 1423
length of query: 688
length of database: 18,247,518
effective HSP length: 109
effective length of query: 579
effective length of database: 14,120,124
effective search space: 8175551796
effective search space used: 8175551796
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.