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Search of human proteins with 41350318
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41350318 myotubularin-related protein 2 isoform 2 [Homo
sapiens]
(571 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 1169 0.0
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 1169 0.0
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 1169 0.0
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 885 0.0
gi|4557896 myotubularin [Homo sapiens] 798 0.0
gi|21361759 myotubularin related protein 8 [Homo sapiens] 377 e-104
gi|134142348 myotubularin related protein 6 [Homo sapiens] 371 e-102
gi|225543474 myotubularin related protein 7 [Homo sapiens] 357 2e-98
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 350 2e-96
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 350 2e-96
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 350 2e-96
gi|19923424 myotubularin related protein 9 [Homo sapiens] 333 2e-91
gi|217272865 myotubularin related protein 4 [Homo sapiens] 328 6e-90
gi|29788755 SET binding factor 2 [Homo sapiens] 174 2e-43
gi|124028527 myotubularin related protein 10 [Homo sapiens] 165 9e-41
gi|239735519 SET binding factor 1 [Homo sapiens] 147 3e-35
gi|94721263 myotubularin related protein 12 [Homo sapiens] 144 3e-34
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 143 5e-34
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 141 2e-33
gi|117938274 jumpy isoform 3 [Homo sapiens] 40 0.008
gi|117938272 jumpy isoform 1 [Homo sapiens] 40 0.008
gi|117938270 jumpy isoform 2 [Homo sapiens] 40 0.008
gi|238231453 dual specificity phosphatase 7 [Homo sapiens] 33 0.71
gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo s... 32 1.6
gi|18087825 aspartoacylase 3 [Homo sapiens] 32 2.1
gi|49355807 leucine zipper, down-regulated in cancer 1-like [Hom... 32 2.1
gi|4503421 dual specificity phosphatase 9 [Homo sapiens] 30 4.6
gi|155030240 tRNA nucleotidyl transferase, CCA-adding, 1 [Homo s... 30 7.8
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 30 7.8
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 30 7.8
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 1169 bits (3023), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI
Sbjct: 73 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 132
Query: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
Sbjct: 133 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 192
Query: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD
Sbjct: 193 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 252
Query: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ
Sbjct: 253 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 312
Query: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP
Sbjct: 313 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 372
Query: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 373 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 432
Query: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
Sbjct: 433 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 492
Query: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT
Sbjct: 493 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 552
Query: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE
Sbjct: 553 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 612
Query: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
ELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 613 ELQREISNRSTSSSERASSPAQCVTPVQTVV 643
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 1169 bits (3023), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
ELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 1169 bits (3023), Expect = 0.0
Identities = 571/571 (100%), Positives = 571/571 (100%)
Query: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI
Sbjct: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
Query: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL
Sbjct: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
Query: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD
Sbjct: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
Query: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ
Sbjct: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
Query: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP
Sbjct: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
Query: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
Query: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR
Sbjct: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
Query: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT
Sbjct: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
Query: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE
Sbjct: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
Query: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
ELQREISNRSTSSSERASSPAQCVTPVQTVV
Sbjct: 541 ELQREISNRSTSSSERASSPAQCVTPVQTVV 571
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 885 bits (2288), Expect = 0.0
Identities = 418/572 (73%), Positives = 493/572 (86%), Gaps = 2/572 (0%)
Query: 1 MEEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVI 60
MEE PL PGE+IK + KDV YICPF GAV GTLTVT+++LYFK++ERDP F+LD LGVI
Sbjct: 95 MEEAPLFPGESIKAIVKDVMYICPFMGAVSGTLTVTDFKLYFKNVERDPHFILDVPLGVI 154
Query: 61 NRVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPL 120
+RVEKIG A S G+NS G+E VCKD+RNLR A+K E +++ IFENL K+AFP+SN L
Sbjct: 155 SRVEKIG-AQSHGDNSCGIEIVCKDMRNLRLAYKQEEQSKLGIFENLNKHAFPLSNGQAL 213
Query: 121 FAFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPD 180
FAF YKE FP NGWK+YDP+ EY+RQG+PNESW+I+KIN YE CDTYPA++VVP ++ D
Sbjct: 214 FAFSYKEKFPINGWKVYDPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVPTSVKD 273
Query: 181 EELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQ 240
++L +VA+FR++GR+PVLSWIHPESQATITRCSQP+VG + KR KEDEKYLQ IMD+NAQ
Sbjct: 274 DDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIMDANAQ 333
Query: 241 SHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP 300
SHK+ IFDAR + A NK KGGGYESE AY NAELVFL+IHNIHVMRESLRKLKEIVYP
Sbjct: 334 SHKLIIFDARQNSVADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRKLKEIVYP 393
Query: 301 NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAM 360
+I+E WLSN++ THWLE+I+++LAGA+RIADK+ESGKTSVVVHCSDGWDRTAQLTSLAM
Sbjct: 394 SIDEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWDRTAQLTSLAM 453
Query: 361 LMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTR 420
LMLD YYRTI+GFE LVEKEW+SFGHRF LRVGHG+ NHADADRSP+FLQF+DCVWQMTR
Sbjct: 454 LMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQFVDCVWQMTR 513
Query: 421 QFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFT 480
QFP+AFEFNE FLITILDHLYSCLFGTFLCN EQQR KE++ +T+SLWSYINSQL++F+
Sbjct: 514 QFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFKEDVYTKTISLWSYINSQLDEFS 573
Query: 481 NPLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVE 540
NP + +Y NHVLYPVAS+ HLELWV YY+RWNPRM+PQ PIH KELLA RAELQK+VE
Sbjct: 574 NPFFVNYENHVLYPVASLSHLELWVNYYVRWNPRMRPQMPIHQNLKELLAVRAELQKRVE 633
Query: 541 ELQREISNRS-TSSSERASSPAQCVTPVQTVV 571
LQRE++ R+ +SSSER SSP+ T V T V
Sbjct: 634 GLQREVATRAVSSSSERGSSPSHSATSVHTSV 665
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 798 bits (2062), Expect = 0.0
Identities = 381/570 (66%), Positives = 460/570 (80%), Gaps = 3/570 (0%)
Query: 2 EEPPLLPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFKSMERDPPFVLDASLGVIN 61
E P LPGE + K+V YICPF G ++G + +TNYRLY +S+E D +LD LGVI+
Sbjct: 33 EAVPRLPGETLIT-DKEVIYICPFNGPIKGRVYITNYRLYLRSLETDSSLILDVPLGVIS 91
Query: 62 RVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLF 121
R+EK+GGA+SRGENSYGL+ CKD+RNLRFA K EG +RR +FE L +YAFP++++LPLF
Sbjct: 92 RIEKMGGATSRGENSYGLDITCKDMRNLRFALKQEGHSRRDMFEILTRYAFPLAHSLPLF 151
Query: 122 AFEYKEVFPENGWKLYDPLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDE 181
AF +E F +GW +Y+P+ EYRRQG+PN WRIT IN+ YELCDTYPALLVVP D+
Sbjct: 152 AFLNEEKFNVDGWTVYNPVEEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDD 211
Query: 182 ELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQS 241
+L+RVA+FRSR RIPVLSWIHPE++ I RCSQP+VG+SGKR+K+DEKYL I ++N Q
Sbjct: 212 DLRRVATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQI 271
Query: 242 HKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPN 301
K+ I+DARPSVNAVANKA GGGYES+DAY NAEL FLDIHNIHVMRESL+K+K+IVYPN
Sbjct: 272 SKLTIYDARPSVNAVANKATGGGYESDDAYHNAELFFLDIHNIHVMRESLKKVKDIVYPN 331
Query: 302 IEETHWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAML 361
+EE+HWLS+LESTHWLEHIKL+L GA+++ADKV SGK+SV+VHCSDGWDRTAQLTSLAML
Sbjct: 332 VEESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAML 391
Query: 362 MLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQ 421
MLD +YR+I GFE+LV+KEW+SFGH+F R+GHGDKNH DADRSP+FLQFIDCVWQM++Q
Sbjct: 392 MLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQ 451
Query: 422 FPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTN 481
FPTAFEFNE FLI ILDHLYSC FGTFL N E R ++ + +RTVSLWS INS E F N
Sbjct: 452 FPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSLWSLINSNKEKFKN 511
Query: 482 PLYGSYSNHVLYPVASMRHLELWVGYYIRWNPRMKPQE--PIHNRYKELLAKRAELQKKV 539
P Y N VLYPVASMRHLELWV YYIRWNPR+K Q+ P+ RY ELLA R E K++
Sbjct: 512 PFYTKEINRVLYPVASMRHLELWVNYYIRWNPRIKQQQPNPVEQRYMELLALRDEYIKRL 571
Query: 540 EELQREISNRSTSSSERASSPAQCVTPVQT 569
EELQ S + + SSP+Q + VQT
Sbjct: 572 EELQLANSAKLSDPPTSPSSPSQMMPHVQT 601
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 377 bits (969), Expect = e-104
Identities = 200/481 (41%), Positives = 294/481 (61%), Gaps = 20/481 (4%)
Query: 87 RNLRFAH--KPEGRTRRSIFENLMKYAFPVSNNLP--LFAFEYK----EVFPENGWKLYD 138
+N R AH ++ +L+K + P LP L+AF Y + E+GWKL D
Sbjct: 75 KNFRVAHFVLDSDLVCHEVYISLLKLSQPA---LPEDLYAFSYNPKSSKEMRESGWKLID 131
Query: 139 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 198
P+ ++ R GIPN +W IT N YE+C TYP +VVP ++ + + FRS+ R+PVL
Sbjct: 132 PISDFGRMGIPNRNWTITDANRNYEICSTYPPEIVVPKSVTLGTVVGSSKFRSKERVPVL 191
Query: 199 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 258
S+++ E+ A I RCSQP+ G R +DE L+AI +N S +++ D RP +NA+AN
Sbjct: 192 SYLYKENNAAICRCSQPLSGFY-TRCVDDELLLEAISQTNPGSQFMYVVDTRPKLNAMAN 250
Query: 259 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTH 315
+A G GYE+ED Y N F+ I NIHVMR SL+KL E+ P + E +LS LES+
Sbjct: 251 RAAGKGYENEDNYANIRFRFMGIENIHVMRSSLQKLLEVCELKTPTMSE--FLSGLESSG 308
Query: 316 WLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEV 375
WL HIK I+ + I V+ K SV+VHCSDGWDRTAQ+ S+A ++LD +YRT +G +
Sbjct: 309 WLRHIKAIMDAGIFITKAVKVEKASVLVHCSDGWDRTAQVCSVASILLDPFYRTFKGLMI 368
Query: 376 LVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLIT 435
L+EKEW+S GH+F R GH D + + SP+F QF+DC+WQ+ QFP AFEFNE FL+
Sbjct: 369 LIEKEWISMGHKFSQRCGHLDGDSKEV--SPIFTQFLDCIWQLMEQFPCAFEFNENFLLE 426
Query: 436 ILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH-VLYP 494
I DH++SC FG FL N ++ R + ++T S+W ++ + DF NPLY ++ + VL P
Sbjct: 427 IHDHVFSCQFGNFLGNCQKDREDLRVYEKTHSVWPFLVQRKPDFRNPLYKGFTMYGVLNP 486
Query: 495 VASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSS 554
+++ W G Y R++ ++P++ + E+ +RA L+ V EL++++ R
Sbjct: 487 STVPYNIQFWCGMYNRFDKGLQPKQSMLESLLEIKKQRAMLETDVHELEKKLKVRDEPPE 546
Query: 555 E 555
E
Sbjct: 547 E 547
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 371 bits (952), Expect = e-102
Identities = 203/535 (37%), Positives = 308/535 (57%), Gaps = 19/535 (3%)
Query: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
++ GTL +T L F + ++L + VEK+ +S L CK+ R
Sbjct: 24 SLTGTLYLTATHLLFIDSHQKETWILHHHIA---SVEKLALTTS----GCPLVIQCKNFR 76
Query: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----GWKLYDPLLEY 143
+ F P R I+ +L++ + L+AF Y ++ GW+L D EY
Sbjct: 77 TVHFI-VPRERDCHDIYNSLLQLSKQAKYE-DLYAFSYNPKQNDSERLQGWQLIDLAEEY 134
Query: 144 RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHP 203
+R G+PN W+++ N Y++C+TYP L VP + + FRS+GR PVLS+ H
Sbjct: 135 KRMGVPNSHWQLSDANRDYKICETYPRELYVPRIASKPIIVGSSKFRSKGRFPVLSYYHQ 194
Query: 204 ESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGG 263
+ +A I RCSQP+ G S R EDE LQAI +N + +++ D RP +NA+AN+A G
Sbjct: 195 DKEAAICRCSQPLSGFSA-RCLEDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGK 253
Query: 264 GYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIV-YPNIEETHWLSNLESTHWLEHIKL 322
GYE+ED Y N F+ I NIHVMR SL+KL E+ + + S LES+ WL HIK
Sbjct: 254 GYENEDNYSNIRFQFVGIENIHVMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKA 313
Query: 323 ILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWL 382
++ A+ +A + SV+VHCSDGWDRT+Q+ SL L+LD YYRTI+GF VL+EK+W+
Sbjct: 314 VMDAAIFLAKAITVENASVLVHCSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWI 373
Query: 383 SFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYS 442
SFGH+F R G D + + SPVF QF++CVW +T QFP AFEF+E FL+ I +H++S
Sbjct: 374 SFGHKFSERCGQLDGDPKEV--SPVFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHS 431
Query: 443 CLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH--VLYPVASMRH 500
C FG FL N +++R + L ++T SLW ++ + + NPLY S S+ VL P +
Sbjct: 432 CQFGNFLGNCQKEREELKLKEKTYSLWPFLLEDQKKYLNPLYSSESHRFTVLEPNTVSFN 491
Query: 501 LELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSE 555
+ W Y +++ + P++ + N + + +L+K +++L+ +I R ++
Sbjct: 492 FKFWRNMYHQFDRTLHPRQSVFNIIMNMNEQNKQLEKDIKDLESKIKQRKNKQTD 546
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 357 bits (916), Expect = 2e-98
Identities = 207/531 (38%), Positives = 307/531 (57%), Gaps = 32/531 (6%)
Query: 28 AVRGTLTVTNYRLYFKSMERDP---PFVLDASLGVINRVEKIGGASSRGENSYGLETVCK 84
A GTL +T + F DP ++L + + I + + L CK
Sbjct: 23 AALGTLYLTATHVIFVENSPDPRKETWILHSQISTIEK-------QATTATGCPLLIRCK 75
Query: 85 DIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP----ENGWKLYDPL 140
+ + ++ P+ R ++ +L++ A PV L+ F + + E GW L D
Sbjct: 76 NFQIIQLII-PQERDCHDVYISLIRLARPVKYE-ELYCFSFNPMLDKEEREQGWVLIDLS 133
Query: 141 LEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSW 200
EY R G+PN W+++ +N Y +CD+YP L VP + + + FRSR R PVLS+
Sbjct: 134 EEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPVLSY 193
Query: 201 IHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKA 260
+ ++ A+I R SQP+ G S R EDE+ LQAI +N S +++ D RP +NA+AN+A
Sbjct: 194 YYKDNHASICRSSQPLSGFSA-RCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMANRA 252
Query: 261 KGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVY---PNIEETHWLSNLESTHWL 317
G GYE+ED Y N + F+ I NIHVMR SL+K+ E+ P++ + W LE++ WL
Sbjct: 253 AGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLW--GLENSGWL 310
Query: 318 EHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLV 377
HIK I+ + IA V SV+VHCSDGWDRTAQ+ S+A L+LD +YRT++GF VL+
Sbjct: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
Query: 378 EKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITIL 437
EK+W+SFGH+F R G+ D + + SPV QFI+CVWQ+ QFP AFEFNE FLI I
Sbjct: 371 EKDWISFGHKFNHRYGNLDGDPKEI--SPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQ 428
Query: 438 DHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLY---GSYSNHVLY- 493
H+YSC FG FLCNS+++R + + +RT SLW+++ D+ NPL+ S + L+
Sbjct: 429 HHIYSCQFGNFLCNSQKERRELKIQERTYSLWAHLWKNRADYLNPLFRADHSQTQGTLHL 488
Query: 494 PVASMRHL-ELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQ 543
P + + W G Y R+ M+P++ + + L+A + E Q+ EEL+
Sbjct: 489 PTTPCNFMYKFWSGMYNRFEKGMQPRQSVTD---YLMAVKEETQQLEEELE 536
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 33 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 92
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 93 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 138
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 139 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 189
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 190 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 236
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 237 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 264
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 265 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 324
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 325 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 384
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 385 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 444
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 445 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 504
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 505 VGYYIRWNPRMKPQEPI 521
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 33 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 92
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 93 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 138
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 139 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 189
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 190 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 236
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 237 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 264
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 265 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 324
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 325 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 384
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 385 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 444
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 445 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 504
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 505 VGYYIRWNPRMKPQEPI 521
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 350 bits (898), Expect = 2e-96
Identities = 214/557 (38%), Positives = 300/557 (53%), Gaps = 91/557 (16%)
Query: 33 LTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIRNLRFA 92
+ ++NYRL+ K E +++ L +I VE + + L CKD + +R
Sbjct: 53 IALSNYRLHIKFKES----LVNVPLQLIESVEC--------RDIFQLHLTCKDCKVIR-- 98
Query: 93 HKPEGRTRRSIFENLMKYAFPVSNNL-------PLFAFEYK----EVFP---ENGWKLYD 138
+ S FE ++ ++N + LF+F Y EV+ E L
Sbjct: 99 ------CQFSTFEQCQEWLKRLNNAIRPPAKIEDLFSFAYHAWCMEVYASEKEQHGDLCR 152
Query: 139 P--------LLEYRRQGIP-NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASF 189
P E R G N +WRI+ INE+Y+LC +YP L+VPA I D+EL+ V+SF
Sbjct: 153 PGEHVTSRFKNEVERMGFDMNNAWRISNINEKYKLCGSYPQELIVPAWITDKELESVSSF 212
Query: 190 RSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD------------- 236
RS RIP + + H + A I RC QP V G R+ +DE +Q++
Sbjct: 213 RSWKRIPAVIYRHQSNGAVIARCGQPEVSWWGWRNADDEHLVQSVAKACASDSRSSGSKL 272
Query: 237 ------------------------SNA--------QSHKIFIFDARPSVNAVANKAKGGG 264
SNA Q K+ I DAR AVAN+AKGGG
Sbjct: 273 STRNTSRDFPNGGDLSDVEFDSSLSNASGAESLAIQPQKLLILDARSYAAAVANRAKGGG 332
Query: 265 YESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLIL 324
E + Y N E+VF+ + NIH +R S + L+ + + +WLS LEST WL H+ ++L
Sbjct: 333 CECPEYYPNCEVVFMGMANIHSIRRSFQSLRLLCTQMPDPGNWLSALESTKWLHHLSVLL 392
Query: 325 AGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSF 384
AL + V+ + V+VHCSDGWDRT Q+ +LA L+LD YYRTI GF+VLVE EWL F
Sbjct: 393 KSALLVVHAVDQDQRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDF 452
Query: 385 GHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCL 444
GH+F R GHG+ + +R PVFLQ++DCV Q+ RQFP +FEFNE FL+ ++ H YSCL
Sbjct: 453 GHKFADRCGHGENSDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCL 512
Query: 445 FGTFLCNSEQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELW 504
FGTFLCN+ ++RG+++ +RT S+WS + + + F N LY S S VLYPV +R+L LW
Sbjct: 513 FGTFLCNNAKERGEKHTQERTCSVWSLLRAGNKAFKNLLYSSQSEAVLYPVCHVRNLMLW 572
Query: 505 VGYYIRWNPRMKPQEPI 521
Y+ P P P+
Sbjct: 573 SAVYL---PCPSPTTPV 586
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 333 bits (855), Expect = 2e-91
Identities = 199/547 (36%), Positives = 305/547 (55%), Gaps = 30/547 (5%)
Query: 24 PFTGAVRGTLTVTNYRLYFKSMERDPP--FVLDASLGVINRVEKIGGASSRGENSYGLET 81
PF AV GTL +T + L S + + ++L +++ I++ R S G
Sbjct: 20 PFYPAVEGTLCLTGHHLILSSRQDNTEELWLLHSNIDAIDK---------RFVGSLGTII 70
Query: 82 V-CKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFP--ENGWKLYD 138
+ CKD R ++ P +I ++ + S L ++ F Y+ +F E+GW +
Sbjct: 71 IKCKDFRIIQL-DIPGMEECLNIASSIEALSTLDSITL-MYPFFYRPMFEVIEDGWHSFL 128
Query: 139 PLLEYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVL 198
P E+ WR++ +N+ + +C +YP ++ VP +I DE L++VA+FR GR PVL
Sbjct: 129 PEQEFELYSSATSEWRLSYVNKEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVL 188
Query: 199 SWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVAN 258
S+ H ++ I R QP+ G +G+R KEDEK + A + + + +I D R A
Sbjct: 189 SYYHKKNGMVIMRSGQPLTGTNGRRCKEDEKLINATLRAGKRG---YIIDTRSLNVAQQT 245
Query: 259 KAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETH----WLSNLEST 314
+AKGGG+E E Y + I H+++ESL KL E ++TH WLS LE++
Sbjct: 246 RAKGGGFEQEAHYPQWRRIHKSIERYHILQESLIKLVEACN---DQTHNMDRWLSKLEAS 302
Query: 315 HWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFE 374
+WL HIK IL A A ++ S+++H ++G D T Q+TSLA ++L+ RTIRGFE
Sbjct: 303 NWLTHIKEILTTACLAAQCIDREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFE 362
Query: 375 VLVEKEWLSFGHRFQLRVGHGDK-NHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFL 433
L+E+EWL GH FQ R N +PVFL F+DCVWQ+ RQFP +FEFNE FL
Sbjct: 363 ALIEREWLQAGHPFQQRCAQSAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFL 422
Query: 434 ITILDHLYSCLFGTFLCNSEQQRGKENLPKRTVSLWSYIN--SQLEDFTNPLYGSYSNHV 491
I + +H Y+ FGTFL N+E +R K L ++T+SLWS++N S+L FTNPL+ + +N V
Sbjct: 423 IMLFEHAYASQFGTFLGNNESERCKLKLQQKTMSLWSWVNQPSELSKFTNPLFEA-NNLV 481
Query: 492 LYPVASMRHLELWVGYYIRWNPRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRST 551
++P + + L LW G ++RWN K + + ++ ELQ KV L+R+++ T
Sbjct: 482 IWPSVAPQSLPLWEGIFLRWNRSSKYLDEAYEEMVNIIEYNKELQAKVNILRRQLAELET 541
Query: 552 SSSERAS 558
+ S
Sbjct: 542 EDGMQES 548
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 328 bits (842), Expect = 6e-90
Identities = 195/537 (36%), Positives = 286/537 (53%), Gaps = 68/537 (12%)
Query: 28 AVRGTLTVTNYRLYFKSMERDPPFVLDASLGVINRVEKIGGASSRGENSYGLETVCKDIR 87
A + ++NYRL+ K + V++ L +I+ VE + + L CKD +
Sbjct: 48 AADALIAISNYRLHIKFKDS----VINVPLRMIDSVES--------RDMFQLHISCKDSK 95
Query: 88 NLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKE-----VFPENGWKLYDP--- 139
+R H + + L + + LFAF Y + L P
Sbjct: 96 VVR-CHFSTFKQCQEWLSRLSRATARPAKPEDLFAFAYHAWCLGLTEEDQHTHLCQPGEH 154
Query: 140 -----LLEYRRQGIPNES-WRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRG 193
E R G ++ WR++ IN Y+LC +YP L+VP I D+EL+ VASFRS
Sbjct: 155 IRCRQEAELARMGFDLQNVWRVSHINSNYKLCPSYPQKLLVPVWITDKELENVASFRSWK 214
Query: 194 RIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAI------------------- 234
RIPV+ + H + A I RCSQP + G R+ +DE + +I
Sbjct: 215 RIPVVVYRHLRNGAAIARCSQPEISWWGWRNADDEYLVTSIAKACALDPGTRATGGSLST 274
Query: 235 ----------------------MDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQ 272
++S A K+ I DAR AVAN+AKGGG E E+ Y
Sbjct: 275 GNNDTSEACDADFDSSLTACSGVESTAAPQKLLILDARSYTAAVANRAKGGGCECEEYYP 334
Query: 273 NAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIKLILAGALRIAD 332
N E+VF+ + NIH +R S + L+ + + ++WLS LEST WL+H+ ++L A+ +A+
Sbjct: 335 NCEVVFMGMANIHAIRNSFQYLRAVCSQMPDPSNWLSALESTKWLQHLSVMLKAAVLVAN 394
Query: 333 KVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRV 392
V+ V+VHCSDGWDRT Q+ +LA ++LD YYRT+ GF+VLVE +WL FGH+F R
Sbjct: 395 TVDREGRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRC 454
Query: 393 GHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNS 452
GH + ++ PVFLQ++D V Q+ +QFP FEFNE FL+ ++ H YSCL+GTFL N+
Sbjct: 455 GHQENVEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANN 514
Query: 453 EQQRGKENLPKRTVSLWSYINSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509
+R K N+ KRT S+W+ + + ++F N LY S+ VL+PV +R L LW Y+
Sbjct: 515 PCEREKRNIYKRTCSVWALLRAGNKNFHNFLYTPSSDMVLHPVCHVRALHLWTAVYL 571
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 174 bits (442), Expect = 2e-43
Identities = 136/452 (30%), Positives = 198/452 (43%), Gaps = 96/452 (21%)
Query: 151 ESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATIT 210
E +RIT N Y LC +YP LLVVP + D L RVA R+PV+ W + S +
Sbjct: 1136 EYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLL 1195
Query: 211 RC-------------------SQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIF------ 245
R + P + S E EKYLQA++++ + K+
Sbjct: 1196 RSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLT 1255
Query: 246 ---IFDARPSVNA---------------------VANKAKGGGYESEDAYQN-------- 273
F P V A +A K + + QN
Sbjct: 1256 VRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAA 1315
Query: 274 --------------------AELVFLDIHNIHVMRESLRKLKEIVYPNI----EETHWLS 309
E V ++ H I ++ S +KL P+ E +L
Sbjct: 1316 LYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLK 1375
Query: 310 NLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRT 369
L + W + I+ A+ +++ +E+G +SV+V +GWD TAQ+TSL L+ D +YRT
Sbjct: 1376 ALGDSEWFPQLHRIMQLAVVVSEVLENG-SSVLVCLEEGWDITAQVTSLVQLLSDPFYRT 1434
Query: 370 IRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFN 429
+ GF++LVEKEWLSFGH+F R N + +PVFLQF+DCV Q+ Q+PT FEFN
Sbjct: 1435 LEGFQMLVEKEWLSFGHKFSQR-SSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFN 1493
Query: 430 EYFLITILDHLYSCLFGTFLCNSEQQRGK---------ENLPKRTVSLWSYI---NSQLE 477
Y+L + H S F TFL +S+ +R + E K+ V +W I + +
Sbjct: 1494 LYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSP 1553
Query: 478 DFTNPLYGSYSNHVLYPVASMRHLELWVGYYI 509
F N LY L P ++ L+ W YYI
Sbjct: 1554 IFFNYLYSPLEIEALKPNVNVSSLKKW-DYYI 1584
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 165 bits (418), Expect = 9e-41
Identities = 144/521 (27%), Positives = 228/521 (43%), Gaps = 103/521 (19%)
Query: 3 EPPLLPGENIKDMAKDVTYI--CPFTGAVR----GTLTVTNYRLYFKSM----------- 45
EP LLPGE + +V ++ C T + G L +N+++ F +
Sbjct: 35 EPVLLPGEIV---VNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYR 91
Query: 46 -----ERDPPFVLDASLGVIN---RVEKIGGASSRGE-NSYGLETVCKDIRNLRFAHKPE 96
E D P + +N R +K+ G + + + N L CKD R +RF
Sbjct: 92 NLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDES 151
Query: 97 G-RTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----------------------- 132
G + + + + Y+ P L LFAFEY N
Sbjct: 152 GPESAKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGA 210
Query: 133 --GWKLYDPLLE--------YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEE 182
G PL E +R G WR+ INE Y + P +VVP+++ D++
Sbjct: 211 GGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVPSSLADQD 268
Query: 183 LKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSH 242
LK + R+P+ W H A + ++ ++ K D++ AI S+ Q
Sbjct: 269 LKIFSHSFVGRRMPLWCWSHSNGSALV---RMALIKDVLQQRKIDQRICNAITKSHPQRS 325
Query: 243 KIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEI-VYPN 301
++ D + + NI ++ + KLK++ V
Sbjct: 326 DVYKSDLDKT----------------------------LPNIQEVQAAFVKLKQLCVNEP 357
Query: 302 IEETH--WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 359
EET WLS+LE+T WLE+++ L + + +ES SVV+ +G D + + SL
Sbjct: 358 FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLV 417
Query: 360 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 419
+MLD Y+RTI GF+ L++KEW+ G++F R H ++ + SP+FL F+D WQ+
Sbjct: 418 QVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLL 474
Query: 420 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKEN 460
Q+P AFEF+E +L + D LFGTFL NS QR K++
Sbjct: 475 EQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 147 bits (370), Expect = 3e-35
Identities = 94/281 (33%), Positives = 151/281 (53%), Gaps = 21/281 (7%)
Query: 245 FIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEE 304
F+ R ++ + +KA+ G S D Q ELV +++ ++ S +KL + P
Sbjct: 1344 FLRPQRAALYILGDKAQLKGVRS-DPLQQWELVPIEVFEARQVKASFKKLLKACVPGCPA 1402
Query: 305 TH-----WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 359
+L +LE + WL I +L ++ + + ++SG +SV+V DGWD T Q+ SL
Sbjct: 1403 AEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSG-SSVLVGLEDGWDITTQVVSLV 1461
Query: 360 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 419
L+ D +YRT+ GF +LVEKEWLSFGHRF R H + + +PVFLQF+DCV Q+
Sbjct: 1462 QLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQS-SGFTPVFLQFLDCVHQVH 1520
Query: 420 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSE----------QQRGKENLPKRTVSLW 469
QFP FEF++++L + H S F TFL +S+ +++G+ S+W
Sbjct: 1521 LQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELGLLYEEKGERRGQVPCRSVW 1580
Query: 470 SYI---NSQLEDFTNPLYGSYSNHVLYPVASMRHLELWVGY 507
Y+ + + F N +Y VL P +++ +L++W Y
Sbjct: 1581 EYVDRLSKRTPVFHNYMYAPEDAEVLRPYSNVSNLKVWDFY 1621
Score = 59.7 bits (143), Expect = 7e-09
Identities = 33/105 (31%), Positives = 51/105 (48%), Gaps = 17/105 (16%)
Query: 150 NESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATI 209
+E +RI+ +N Y +C +YP LL+VP ++ D L+RV+ + R PV+ W S+A +
Sbjct: 1147 SEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGRSKAVL 1206
Query: 210 TR-----------------CSQPMVGVSGKRSKEDEKYLQAIMDS 237
R P + S E EKYLQA++ S
Sbjct: 1207 LRSGGLHGKGVVGLFKAQNAPSPGQSQADSSSLEQEKYLQAVVSS 1251
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 144 bits (362), Expect = 3e-34
Identities = 126/435 (28%), Positives = 196/435 (45%), Gaps = 69/435 (15%)
Query: 83 CKDIRNLRFA--HKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVF-------PENG 133
CKD+R +F + E +R I ++ + LF F Y P+N
Sbjct: 143 CKDLRVFQFCLRYTKEEEVKR-IVSGIIHHTQAPKLLKRLFLFSYATAAQNNTVTDPKNH 201
Query: 134 WKLYDPLLEY-----RRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVAS 188
++D L ++ R +G N ++ +NE Y++C+ PA VVP +P+E ++R
Sbjct: 202 TVMFDTLKDWCWELERTKG--NMKYKAVSVNEGYKVCERLPAYFVVPTPLPEENVQR--- 256
Query: 189 FRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFD 248
F+ G IP+ W A + + P KE + + I S I+
Sbjct: 257 FQGHG-IPIWCWSCHNGSALLKMSALP---------KEQDDGILQIQKSFLDG--IYKTI 304
Query: 249 ARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEE---- 304
RP V ++ED N FL + I ++L + N E
Sbjct: 305 HRPPYEIV---------KTEDLSSN----FLSLQEIQTAYSKFKQL--FLIDNSTEFWDT 349
Query: 305 -THWLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLML 363
W S LES+ WL+ I+ L A+ I + +E+ +V++ + D ++SL LM+
Sbjct: 350 DIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDLCCLISSLVQLMM 409
Query: 364 DGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFP 423
D + RT GF+ L++KEW+ GH F R H +N D + PVFL F+DCVWQ+ Q P
Sbjct: 410 DPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQN--DKEEVPVFLLFLDCVWQLVHQHP 467
Query: 424 TAFEFNEYFLITILDHLYSCLFGTFLCNSEQQR----GKE-----NLPKRTVSLWSYINS 474
AFEF E +L + D LY +F TF NS Q+ G+E + P +++W + +
Sbjct: 468 PAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQKDTNMGREGQDTQSKPLNLLTVWDW-SV 526
Query: 475 QLED-----FTNPLY 484
Q E NPLY
Sbjct: 527 QFEPKAQTLLKNPLY 541
Score = 31.6 bits (70), Expect = 2.1
Identities = 25/112 (22%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
Query: 459 ENLPKRTVSLWSYINSQLEDFTNPLYGSYSNH------VLYPVASMRHLELWVGYYIRWN 512
+NL + +S + +L+D Y S+ + +L P +++W Y+RW
Sbjct: 588 KNLLGKRISKLINSSDELQDNFREFYDSWHSKSTDYHGLLLPHIEGPEIKVWAQRYLRWI 647
Query: 513 PRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERASSPAQCV 564
P + + L+K E+ ++V+ LQ +I R S + + A C+
Sbjct: 648 PE---AQILGGGQVATLSKLLEMMEEVQSLQEKIDERH-HSQQAPQAEAPCL 695
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 143 bits (360), Expect = 5e-34
Identities = 142/531 (26%), Positives = 227/531 (42%), Gaps = 94/531 (17%)
Query: 7 LPGENIKDMAKDVTYICPFTGAVRGTLTVTNYRLYFK----SMERDPPFVLDASLGVIN- 61
LPGE I A V + GTL TN+R+ F+ +D P + ++N
Sbjct: 46 LPGEQILAWAPGVRK--GLEPELSGTLICTNFRVTFQPCGWQWNQDTPLNSEYDFALVNI 103
Query: 62 -RVEKIGGASSRGENSYGLETVCKDIRNLRFAHKPEGRTRRSIFE--NLMKYAFPVSNNL 118
R+E + G S G ++ K I H + R R FE L AF V+ +
Sbjct: 104 GRLEAVSGLSRVQLLRPG--SLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAI 161
Query: 119 PLFAFEYKEVFPENGWKLYD------------PLLEY------RRQGIPNESWRITKINE 160
+ + +G L PL+E R+ WR++ +NE
Sbjct: 162 VQARAQSNQAQQYSGITLSKAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNE 221
Query: 161 RYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVS 220
R+++ + P VP I D E++R +GR P LSW HP + + RC +
Sbjct: 222 RFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHP-GGSDLLRCGG--FYTA 278
Query: 221 GKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLD 280
+KED + ++ ++ A + + D + ++A D
Sbjct: 279 SDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA----------------------D 314
Query: 281 IHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEHIKLILAGALRIADKVESGK 338
+ H+ +L+ + P ++ E WLS LE T WL++++ L A I+ V S
Sbjct: 315 VQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRV 368
Query: 339 TSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKN 398
SV++ D L+SL L+ RT+ GF+ LV++EW++ GH F R+G
Sbjct: 369 RSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG----G 424
Query: 399 HADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGK 458
++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D + TFL N+ +RGK
Sbjct: 425 TGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGK 484
Query: 459 E---------------------NLPKRTVSLWS----YINSQLEDFTNPLY 484
+ N +S+W Y N+Q+ F NP Y
Sbjct: 485 QSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNAQILQFQNPGY 535
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 141 bits (355), Expect = 2e-33
Identities = 105/370 (28%), Positives = 171/370 (46%), Gaps = 64/370 (17%)
Query: 142 EYRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEELKRVASFRSRGRIPVLSWI 201
E R+ WR++ +NER+++ + P VP I D E++R +GR P LSW
Sbjct: 131 ETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFHQGRGPRLSWH 190
Query: 202 HPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSHKIFIFDARPSVNAVANKAK 261
HP + + RC + +KED + ++ ++ A + + D + ++A
Sbjct: 191 HP-GGSDLLRCGG--FYTASDPNKEDIRAVELML--QAGHSDVVLVDTMDELPSLA---- 241
Query: 262 GGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYP--NIEETHWLSNLESTHWLEH 319
D+ H+ +L+ + P ++ E WLS LE T WL++
Sbjct: 242 ------------------DVQLAHL------RLRALCLPDSSVAEDKWLSALEGTRWLDY 277
Query: 320 IKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLMLDGYYRTIRGFEVLVEK 379
++ L A I+ V S SV++ D L+SL L+ RT+ GF+ LV++
Sbjct: 278 VRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQR 337
Query: 380 EWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMTRQFPTAFEFNEYFLITILDH 439
EW++ GH F R+G ++ +PVFL F+DCVWQ+ +QFP FEF+E+FL+ + D
Sbjct: 338 EWVAAGHPFLTRLG----GTGASEEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDS 393
Query: 440 LYSCLFGTFLCNSEQQRGKE---------------------NLPKRTVSLWS----YINS 474
+ TFL N+ +RGK+ N +S+W Y N+
Sbjct: 394 VRVPDTLTFLRNTPWERGKQSGQLNSYTQVYTPGYSQPPAGNSFNLQLSVWDWDLRYSNA 453
Query: 475 QLEDFTNPLY 484
Q+ F NP Y
Sbjct: 454 QILQFQNPGY 463
>gi|117938274 jumpy isoform 3 [Homo sapiens]
Length = 538
Score = 39.7 bits (91), Expect = 0.008
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 339 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 392
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 393 GHGDK 397
G++
Sbjct: 384 SKGEE 388
>gi|117938272 jumpy isoform 1 [Homo sapiens]
Length = 598
Score = 39.7 bits (91), Expect = 0.008
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 339 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 392
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 393 GHGDK 397
G++
Sbjct: 384 SKGEE 388
>gi|117938270 jumpy isoform 2 [Homo sapiens]
Length = 650
Score = 39.7 bits (91), Expect = 0.008
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)
Query: 339 TSVVVHCSDGWDRTAQLTSLAMLML--DGYYRT-IRGFEVL---VEKEWLSFGHRFQLRV 392
+ ++VHC GWDRT SL L L DG T ++ E+L V +W FGH R+
Sbjct: 324 SGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKPTEILYLTVAYDWFLFGHMLVDRL 383
Query: 393 GHGDK 397
G++
Sbjct: 384 SKGEE 388
>gi|238231453 dual specificity phosphatase 7 [Homo sapiens]
Length = 419
Score = 33.1 bits (74), Expect = 0.71
Identities = 17/50 (34%), Positives = 26/50 (52%), Gaps = 1/50 (2%)
Query: 313 STHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLM 362
S HW +++ A+ D+ S K V+VHC G R+ +T +A LM
Sbjct: 299 SDHWSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVT-VAYLM 347
>gi|59814247 budding uninhibited by benzimidazoles 1 beta [Homo
sapiens]
Length = 1050
Score = 32.0 bits (71), Expect = 1.6
Identities = 16/48 (33%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 524 RYKELLA---KRAELQKKVEELQREISNRSTSSSERASSPAQCVTPVQ 568
R ELL KRAE+QK++EE+++++ T+ ER + P +
Sbjct: 428 REAELLTSAEKRAEMQKQIEEMEKKLKEIQTTQQERTGDQQEETMPTK 475
>gi|18087825 aspartoacylase 3 [Homo sapiens]
Length = 319
Score = 31.6 bits (70), Expect = 2.1
Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 2/68 (2%)
Query: 73 GENSYGLETVCKDIRNLRFAHKPEGRTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN 132
GE SY L++V K+ L +P+G R IF + V + + L F FP
Sbjct: 161 GEESYNLDSVAKNGLGLELGPQPQGVLRADIFSRMRTLVATVLDFIEL--FNQGTAFPAF 218
Query: 133 GWKLYDPL 140
+ Y P+
Sbjct: 219 EMEAYRPV 226
>gi|49355807 leucine zipper, down-regulated in cancer 1-like [Homo
sapiens]
Length = 239
Score = 31.6 bits (70), Expect = 2.1
Identities = 16/45 (35%), Positives = 21/45 (46%)
Query: 513 PRMKPQEPIHNRYKELLAKRAELQKKVEELQREISNRSTSSSERA 557
P M+P P+ N Y+ LA+ K R R TS+S RA
Sbjct: 154 PHMQPDSPLRNNYQGFLAELRRTYKSPLRHARRAQIRKTSASNRA 198
>gi|4503421 dual specificity phosphatase 9 [Homo sapiens]
Length = 384
Score = 30.4 bits (67), Expect = 4.6
Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 1/50 (2%)
Query: 313 STHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLAMLM 362
S HW +++ A+ D+ S V+VHC G R+ +T +A LM
Sbjct: 258 SDHWSQNLSRFFPEAIEFIDEALSQNCGVLVHCLAGVSRSVTVT-VAYLM 306
>gi|155030240 tRNA nucleotidyl transferase, CCA-adding, 1 [Homo
sapiens]
Length = 434
Score = 29.6 bits (65), Expect = 7.8
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 1/82 (1%)
Query: 178 IPDEELKRVASFRSRGRIPVLSWIH-PESQATITRCSQPMVGVSGKRSKEDEKYLQAIMD 236
I ++ L+ + FR GRI H PE+ I ++ + G+SG+R + K +
Sbjct: 191 IQEDYLRILRYFRFYGRIVDKPGDHDPETLEAIAENAKGLAGISGERIWVELKKILVGNH 250
Query: 237 SNAQSHKIFIFDARPSVNAVAN 258
N H I+ D P + AN
Sbjct: 251 VNHLIHLIYDLDVAPYIGLPAN 272
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 29.6 bits (65), Expect = 7.8
Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 266 ESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIK 321
E ++ Q+ E+V D+ +HV + +L ++E++H L LE T + HI+
Sbjct: 947 EIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSH-LKELEDTLQVRHIQ 1001
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 29.6 bits (65), Expect = 7.8
Identities = 16/56 (28%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 266 ESEDAYQNAELVFLDIHNIHVMRESLRKLKEIVYPNIEETHWLSNLESTHWLEHIK 321
E ++ Q+ E+V D+ +HV + +L ++E++H L LE T + HI+
Sbjct: 947 EIKELKQSREIVLEDLKKLHVENDEKLQLLRAELQSLEQSH-LKELEDTLQVRHIQ 1001
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.413
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,138,838
Number of Sequences: 37866
Number of extensions: 969790
Number of successful extensions: 2924
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 2847
Number of HSP's gapped (non-prelim): 47
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.