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Search of human proteins with 41327764
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41327764 aldo-keto reductase family 7, member A2 [Homo
sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 741 0.0
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 613 e-176
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 601 e-172
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 295 4e-80
gi|4504825 potassium voltage-gated channel, shaker-related subfa... 87 2e-17
gi|27436969 potassium voltage-gated channel, shaker-related subf... 87 2e-17
gi|27436964 potassium voltage-gated channel, shaker-related subf... 80 3e-15
gi|27436962 potassium voltage-gated channel, shaker-related subf... 80 3e-15
gi|27436966 potassium voltage-gated channel, shaker-related subf... 80 3e-15
gi|27436971 potassium voltage-gated channel, shaker-related subf... 77 2e-14
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 49 7e-06
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 49 7e-06
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 47 2e-05
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 44 2e-04
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 43 4e-04
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 43 4e-04
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens] 42 9e-04
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 41 0.002
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 40 0.002
gi|213513324 hypothetical protein LOC401115 [Homo sapiens] 34 0.18
gi|153792074 proline rich 12 [Homo sapiens] 34 0.23
gi|241982802 HMG box domain containing 3 [Homo sapiens] 32 0.67
gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens] 31 1.5
gi|48475062 growth differentiation factor 6 precursor [Homo sapi... 31 1.5
gi|154146189 dedicator of cytokinesis 10 [Homo sapiens] 31 1.5
gi|148529025 pleckstrin homology domain containing, family G (wi... 31 1.5
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens] 31 2.0
gi|71999153 hypothetical protein LOC23334 [Homo sapiens] 30 2.6
gi|239754436 PREDICTED: similar to hCG2038817 [Homo sapiens] 30 3.3
gi|239748930 PREDICTED: hypothetical protein XP_002346860 [Homo ... 30 3.3
>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
Length = 359
Score = 741 bits (1912), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV 60
MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV
Sbjct: 1 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV 60
Query: 61 RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR 120
RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR
Sbjct: 61 RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR 120
Query: 121 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE 180
SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE
Sbjct: 121 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE 180
Query: 181 ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE 240
ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE
Sbjct: 181 ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE 240
Query: 241 DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY 300
DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY
Sbjct: 241 DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY 300
Query: 301 HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 359
HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
Sbjct: 301 HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 359
>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
sapiens]
Length = 331
Score = 613 bits (1581), Expect = e-176
Identities = 295/334 (88%), Positives = 306/334 (91%), Gaps = 5/334 (1%)
Query: 25 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84
+R L+ +RP A+VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YSDGQSET
Sbjct: 2 SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSET 56
Query: 85 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 144
ILGGLGL +G DCRVKIATKANPW G SLKPDSVRSQLETSLKRLQCP VDLFYLHAPD
Sbjct: 57 ILGGLGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPD 116
Query: 145 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 204
H PVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMY+ATT
Sbjct: 117 HSAPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATT 176
Query: 205 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 264
RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFG WAE YRN F
Sbjct: 177 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAEIYRNHF 236
Query: 265 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 324
WKEHHFE IALVEKALQAAYGASAPS+TSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE
Sbjct: 237 WKEHHFEGIALVEKALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 296
Query: 325 QNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYF 358
QNLAA EEGPLEPAVVDAFNQAWHL AHECPNYF
Sbjct: 297 QNLAAAEEGPLEPAVVDAFNQAWHLFAHECPNYF 330
>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
Length = 331
Score = 601 bits (1550), Expect = e-172
Identities = 290/335 (86%), Positives = 306/335 (91%), Gaps = 5/335 (1%)
Query: 25 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84
+R L+ +RP A+VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YS+GQSET
Sbjct: 2 SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSET 56
Query: 85 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 144
ILGGLGL LGG DCRVKI TKA P G SLKPDS+R QLETSLKRLQCP+VDLFYLH PD
Sbjct: 57 ILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD 116
Query: 145 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 204
H TPVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA T
Sbjct: 117 HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAIT 176
Query: 205 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 264
RQVETELFPCLRHFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN+WAE YRNR+
Sbjct: 177 RQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRY 236
Query: 265 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 324
WKEHHFE IALVEKALQAAYGASAPS+TSA LRWMYHHSQLQGAHGDAVILGMSSLEQLE
Sbjct: 237 WKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLE 296
Query: 325 QNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 359
QNLAA EEGPLEPAVVDAFNQAWHLV HECPNYFR
Sbjct: 297 QNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331
>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
sapiens]
Length = 249
Score = 295 bits (755), Expect = 4e-80
Identities = 145/181 (80%), Positives = 155/181 (85%), Gaps = 5/181 (2%)
Query: 25 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84
+R L+ +RP A+VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YSDGQSET
Sbjct: 2 SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSET 56
Query: 85 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 144
ILGGLGL +G DCRVKIATKANPW G SLKPDSVRSQLETSLKRLQCP VDLFYLHAPD
Sbjct: 57 ILGGLGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPD 116
Query: 145 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 204
H PVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQ + A
Sbjct: 117 HSAPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPL 176
Query: 205 R 205
R
Sbjct: 177 R 177
>gi|4504825 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 1 [Homo sapiens]
Length = 367
Score = 87.0 bits (214), Expect = 2e-17
Identities = 77/278 (27%), Positives = 127/278 (45%), Gaps = 22/278 (7%)
Query: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119
+ G DTA +Y+ G++E +LG + G + I TK W GK+ L +
Sbjct: 78 DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF-WGGKAETERGLSRKHI 136
Query: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179
L+ SL+RLQ VD+ + + PD TP+EET+ A + +G + G S ++S E+
Sbjct: 137 IEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIM 196
Query: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238
E ++ + P Q Y+ R+ VE +L G+ ++PLA G+++GKY
Sbjct: 197 EAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKY- 255
Query: 239 YEDKDGKQPVGR--FFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAAL 296
G P R G W +++ E A + K LQA ++ A+
Sbjct: 256 ---DSGIPPYSRASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAI 308
Query: 297 RWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334
W L+ +V+LG S+ +QL +N+ A + P
Sbjct: 309 AWC-----LRNEGVSSVLLGASNADQLMENIGAIQVLP 341
>gi|27436969 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 2 [Homo sapiens]
Length = 353
Score = 87.0 bits (214), Expect = 2e-17
Identities = 77/278 (27%), Positives = 127/278 (45%), Gaps = 22/278 (7%)
Query: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119
+ G DTA +Y+ G++E +LG + G + I TK W GK+ L +
Sbjct: 64 DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF-WGGKAETERGLSRKHI 122
Query: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179
L+ SL+RLQ VD+ + + PD TP+EET+ A + +G + G S ++S E+
Sbjct: 123 IEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIM 182
Query: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238
E ++ + P Q Y+ R+ VE +L G+ ++PLA G+++GKY
Sbjct: 183 EAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKY- 241
Query: 239 YEDKDGKQPVGR--FFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAAL 296
G P R G W +++ E A + K LQA ++ A+
Sbjct: 242 ---DSGIPPYSRASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAI 294
Query: 297 RWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334
W L+ +V+LG S+ +QL +N+ A + P
Sbjct: 295 AWC-----LRNEGVSSVLLGASNADQLMENIGAIQVLP 327
>gi|27436964 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 3 [Homo sapiens]
Length = 401
Score = 80.1 bits (196), Expect = 3e-15
Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%)
Query: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119
E G DTA +Y+ G++E ILG + G + I TK W GK+ L +
Sbjct: 112 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 170
Query: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179
L+ SL+RLQ VD+ + + PD TP+EE + A + +G + G S +++ E+
Sbjct: 171 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 230
Query: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238
E ++ + I P Q Y+ R+ VE +L G+ ++PLA G+++GKY
Sbjct: 231 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 290
Query: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292
+ + + + W +E R + K IA G + P +
Sbjct: 291 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 340
Query: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334
A+ W L+ +V+LG S+ EQL +NL A + P
Sbjct: 341 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 375
>gi|27436962 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 2 [Homo sapiens]
Length = 408
Score = 80.1 bits (196), Expect = 3e-15
Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%)
Query: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119
E G DTA +Y+ G++E ILG + G + I TK W GK+ L +
Sbjct: 119 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 177
Query: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179
L+ SL+RLQ VD+ + + PD TP+EE + A + +G + G S +++ E+
Sbjct: 178 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 237
Query: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238
E ++ + I P Q Y+ R+ VE +L G+ ++PLA G+++GKY
Sbjct: 238 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 297
Query: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292
+ + + + W +E R + K IA G + P +
Sbjct: 298 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 347
Query: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334
A+ W L+ +V+LG S+ EQL +NL A + P
Sbjct: 348 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 382
>gi|27436966 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 1 [Homo sapiens]
Length = 419
Score = 80.1 bits (196), Expect = 3e-15
Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%)
Query: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119
E G DTA +Y+ G++E ILG + G + I TK W GK+ L +
Sbjct: 130 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 188
Query: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179
L+ SL+RLQ VD+ + + PD TP+EE + A + +G + G S +++ E+
Sbjct: 189 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 248
Query: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238
E ++ + I P Q Y+ R+ VE +L G+ ++PLA G+++GKY
Sbjct: 249 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 308
Query: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292
+ + + + W +E R + K IA G + P +
Sbjct: 309 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 358
Query: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334
A+ W L+ +V+LG S+ EQL +NL A + P
Sbjct: 359 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 393
>gi|27436971 potassium voltage-gated channel, shaker-related
subfamily, beta member 3 [Homo sapiens]
Length = 404
Score = 77.4 bits (189), Expect = 2e-14
Identities = 87/341 (25%), Positives = 142/341 (41%), Gaps = 44/341 (12%)
Query: 23 PEARALAMSRPPPP------------------------RVASV-LGT-MEMGRRMDAPAS 56
P+ARA + RPP P RV+ + LGT + G ++ +
Sbjct: 51 PKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETA 110
Query: 57 AAAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS--- 113
+ E G DTA +Y+ G++E LG + G I TK W G++
Sbjct: 111 EDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF-WGGQAETE 169
Query: 114 --LKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLS 171
L + L SL+RLQ VD+ + + D P+EE + A + +G + G S
Sbjct: 170 RGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTS 229
Query: 172 NYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAG 230
+ + E+ E ++ + I P Q ++ R+ VE +L G+ + PLA
Sbjct: 230 RWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLAC 289
Query: 231 GLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPS 290
GL+T KY DG+ P + +++ E + A V L A+ +
Sbjct: 290 GLITSKY-----DGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGC-T 343
Query: 291 VTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATE 331
V A+ W L+ +V+LG+SS EQL ++L A +
Sbjct: 344 VAQLAIAWC-----LRSEGVSSVLLGVSSAEQLIEHLGALQ 379
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 48.9 bits (115), Expect = 7e-06
Identities = 47/146 (32%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
+ P S A AV+ +E G +D+A +Y++ + GL + D VK I +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166
W S +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWSN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
Query: 167 ELGLSNYASWEVAEICT---LCKSNG 189
+ A+WE E C L KS G
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 48.9 bits (115), Expect = 7e-06
Identities = 47/146 (32%), Positives = 67/146 (45%), Gaps = 17/146 (11%)
Query: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
+ P S A AV+ +E G +D+A +Y++ + GL + D VK I +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166
W S +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWSN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
Query: 167 ELGLSNYASWEVAEICT---LCKSNG 189
+ A+WE E C L KS G
Sbjct: 139 FDTVDLCATWEAMEKCKDAGLAKSIG 164
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/146 (31%), Positives = 66/146 (45%), Gaps = 17/146 (11%)
Query: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
+ P S A A + +E G +D+A +Y++ + GL + D VK I +
Sbjct: 28 EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166
W S +P+ VR LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWCN-SHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIPK----DENGKIL 138
Query: 167 ELGLSNYASWEVAEICT---LCKSNG 189
+ A+WE E C L KS G
Sbjct: 139 FDTVDLCATWEAVEKCKDAGLAKSIG 164
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 15/132 (11%)
Query: 64 LERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKANPWDGKSLKPDSVR 120
+E G +D+A++Y++ + GL + D VK I + W +P V+
Sbjct: 42 IEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWC-TFFQPQMVQ 96
Query: 121 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE 180
LE+SLK+LQ VDL+ LH P P E L + GK + + A+WEV E
Sbjct: 97 PALESSLKKLQLDYVDLYLLHFPMALKPGETPLPK----DENGKVIFDTVDLSATWEVME 152
Query: 181 ICT---LCKSNG 189
C L KS G
Sbjct: 153 KCKDAGLAKSIG 164
>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 43.1 bits (100), Expect = 4e-04
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 30/192 (15%)
Query: 58 AAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC--RVKIATKANPWDGKSLK 115
AAV+ L G+ +D A +Y G I L +G G R ++ + W+ K
Sbjct: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKH-H 87
Query: 116 PDSVRSQLETSLKRLQCPQVDLFYLHAP---DHG----------------TPVEETLHAC 156
P+ V L +L LQ +DL+ +H P + G T +ET A
Sbjct: 88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Query: 157 QRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLR 216
+ L +G LGLSN+ S ++ +I ++ + P V Q + EL +
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQ--VECHPYLAQNELIAHCQ 201
Query: 217 HFGLRFYAYNPL 228
GL AY+PL
Sbjct: 202 ARGLEVTAYSPL 213
>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 43.1 bits (100), Expect = 4e-04
Identities = 51/192 (26%), Positives = 79/192 (41%), Gaps = 30/192 (15%)
Query: 58 AAVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDC--RVKIATKANPWDGKSLK 115
AAV+ L G+ +D A +Y G I L +G G R ++ + W+ K
Sbjct: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPGKAVPREELFVTSKLWNTKH-H 87
Query: 116 PDSVRSQLETSLKRLQCPQVDLFYLHAP---DHG----------------TPVEETLHAC 156
P+ V L +L LQ +DL+ +H P + G T +ET A
Sbjct: 88 PEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHYKETWKAL 147
Query: 157 QRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLR 216
+ L +G LGLSN+ S ++ +I ++ + P V Q + EL +
Sbjct: 148 EALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQ--VECHPYLAQNELIAHCQ 201
Query: 217 HFGLRFYAYNPL 228
GL AY+PL
Sbjct: 202 ARGLEVTAYSPL 213
>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
Length = 326
Score = 42.0 bits (97), Expect = 9e-04
Identities = 47/178 (26%), Positives = 77/178 (43%), Gaps = 15/178 (8%)
Query: 42 LGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSETILG-GLGLGLGGGDCRV 100
LGT + A A +V+ ++ G+ +D A++Y Q+E +G + + G R
Sbjct: 23 LGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIY---QNEHEVGEAIREKIAEGKVRR 79
Query: 101 KIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLH 160
+ + P+ VR LE +L+ LQ VDL+ + P P +E
Sbjct: 80 EDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPGDEIYPR----D 135
Query: 161 QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETEL-FPCLRH 217
+ GK++ + A+WE E CK G + G+ N RQ+E L P L+H
Sbjct: 136 ENGKWLYHKSNLCATWEAME---ACKDAGLVKSL---GVSNFNRRQLELILNKPGLKH 187
>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
Length = 323
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/146 (28%), Positives = 63/146 (43%), Gaps = 17/146 (11%)
Query: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
+ P S A + +E G +D+A +Y++ + GL + D VK I +
Sbjct: 28 EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFV 166
W +P+ VR LE SLK+ Q VDL+ +H+P P EE + GK +
Sbjct: 84 KLWSTFH-RPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVI 138
Query: 167 ELGLSNYASWEVAEICT---LCKSNG 189
+ +WE E C L KS G
Sbjct: 139 FDIVDLCTTWEAMEKCKDAGLAKSIG 164
>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
Length = 139
Score = 40.4 bits (93), Expect = 0.002
Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 10/97 (10%)
Query: 52 DAPASAA--AVRAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVK---IATKA 106
+ P S A AV+ +E G +D+A +Y++ + GL + D VK I +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 107 NPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAP 143
W S +P+ VR LE SLK LQ VDL+ +H P
Sbjct: 84 KLWSN-SHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
>gi|213513324 hypothetical protein LOC401115 [Homo sapiens]
Length = 139
Score = 34.3 bits (77), Expect = 0.18
Identities = 27/88 (30%), Positives = 38/88 (43%), Gaps = 12/88 (13%)
Query: 11 RAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRA-------- 62
RAA L PP A MS PPPP + +L +G R A + +AV A
Sbjct: 36 RAAPLPLLAMAPPPACRSPMSPPPPPLLLLLLSLALLGARARAEPAGSAVPAQSRPCVDC 95
Query: 63 ----FLERGHTELDTAFMYSDGQSETIL 86
F++R +L D ++ET+L
Sbjct: 96 HAFEFMQRALQDLRKTACSLDARTETLL 123
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/94 (29%), Positives = 39/94 (41%), Gaps = 7/94 (7%)
Query: 25 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84
A A +RPPPPR + +G A A+ A A G YS GQ +
Sbjct: 398 AAAGGATRPPPPRSTATPKCQSLGGPAAAYATGKASGAGGAGGQA-------YSPGQPQG 450
Query: 85 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDS 118
+LG G G G + + +KA + G +P S
Sbjct: 451 LLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPS 484
>gi|241982802 HMG box domain containing 3 [Homo sapiens]
Length = 1292
Score = 32.3 bits (72), Expect = 0.67
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 4/97 (4%)
Query: 6 SRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDA---PASAAAVRA 62
+ V+ + A ++ +A +A PP R A V+ T E + +D P S +A+
Sbjct: 933 TEVIEQVAFPASIPITKFDASVIAPFFPPLMRGAVVVNT-EKDKNLDVQPVPGSGSALVR 991
Query: 63 FLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCR 99
L+ G +LD YS+ + + +L G+ G D +
Sbjct: 992 LLQEGTCKLDEIGSYSEEKLQHLLRQCGIPFGAEDSK 1028
>gi|239753784 PREDICTED: NK1 homeobox 1 [Homo sapiens]
Length = 814
Score = 31.2 bits (69), Expect = 1.5
Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 5/50 (10%)
Query: 4 AASRVVSRAA---VHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRR 50
+ R V R A VH RS P EARALA+ P P RV L +GRR
Sbjct: 207 SGDRSVRRRAHPPVHAPARSHPEEARALAL--PAPTRVHLRLAARCVGRR 254
>gi|48475062 growth differentiation factor 6 precursor [Homo
sapiens]
Length = 455
Score = 31.2 bits (69), Expect = 1.5
Identities = 26/86 (30%), Positives = 32/86 (37%), Gaps = 6/86 (6%)
Query: 24 EARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSE 83
EARA +PPPP + S + GRR+ P A + F L G +E
Sbjct: 246 EARARGPQQPPPPDLRS----LGFGRRVRPPQERALLVVFTRSQRKNLFAEMREQLGSAE 301
Query: 84 TILGGLGLGLGGGDCRVKIATKANPW 109
G G G G A A PW
Sbjct: 302 A--AGPGAGAEGSWPPPSGAPDARPW 325
>gi|154146189 dedicator of cytokinesis 10 [Homo sapiens]
Length = 2186
Score = 31.2 bits (69), Expect = 1.5
Identities = 29/140 (20%), Positives = 54/140 (38%), Gaps = 14/140 (10%)
Query: 188 NGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQP 247
+GW+ Y+G +N+T T +R F R++ L + ++K K+P
Sbjct: 185 SGWL----YKGNFNSTVNNTVT-----VRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEP 235
Query: 248 VGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQG 307
G F +S +N +++ FE K Y A S W++ +++
Sbjct: 236 KGCIFLDSCTGVVQNNRLRKYAFEL-----KMNDLTYFVLAAETESDMDEWIHTLNRILQ 290
Query: 308 AHGDAVILGMSSLEQLEQNL 327
+ + G S E + L
Sbjct: 291 ISPEGPLQGRRSTELTDLGL 310
>gi|148529025 pleckstrin homology domain containing, family G (with
RhoGef domain) member 4B [Homo sapiens]
Length = 1271
Score = 31.2 bits (69), Expect = 1.5
Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 7/121 (5%)
Query: 16 CALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAF 75
CA+ S A+ R P + V GT R A +S+ F T D++
Sbjct: 1140 CAVISDRAPKCAVMSDRVPD---SIVKGTESQMRGSTAVSSSDHAAPFKRPHSTISDSST 1196
Query: 76 MYSDGQSETILGGLGLGLGGGDCRVKIATKA-NPWDG---KSLKPDSVRSQLETSLKRLQ 131
S QS +ILG LGL + + + A +PW ++ D +LET +
Sbjct: 1197 SSSSSQSSSILGSLGLLVSSSPAHPGLWSPAHSPWSSDIRACVEEDEPEPELETGTQAAV 1256
Query: 132 C 132
C
Sbjct: 1257 C 1257
>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 30.8 bits (68), Expect = 2.0
Identities = 22/58 (37%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 2 LSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAA 59
L A SR + R RSP R AM P PR + GT +G + AP +AAA
Sbjct: 163 LGAGSRALRRPGSAALPRSPSSSRRWAAMPGPGAPRPGAP-GTWPVGFAVAAPPAAAA 219
>gi|71999153 hypothetical protein LOC23334 [Homo sapiens]
Length = 2533
Score = 30.4 bits (67), Expect = 2.6
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 311 DAVILG-MSSLEQLEQNLAATEEGPL--EPAVVDAFNQAWHLVAHECPNYF 358
DA +G M S E L Q + E GPL EP V D +Q HE P +F
Sbjct: 101 DAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHF 151
>gi|239754436 PREDICTED: similar to hCG2038817 [Homo sapiens]
Length = 202
Score = 30.0 bits (66), Expect = 3.3
Identities = 19/50 (38%), Positives = 24/50 (48%)
Query: 18 LRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERG 67
LR P P A A RPPP +S L + +G + +A VR ERG
Sbjct: 29 LRFPQPGAPAFTSVRPPPHPASSRLPGLGLGSQPLPVGAAQRVRHASERG 78
>gi|239748930 PREDICTED: hypothetical protein XP_002346860 [Homo
sapiens]
Length = 202
Score = 30.0 bits (66), Expect = 3.3
Identities = 19/50 (38%), Positives = 24/50 (48%)
Query: 18 LRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERG 67
LR P P A A RPPP +S L + +G + +A VR ERG
Sbjct: 29 LRFPQPGAPAFTSVRPPPHPASSRLPGLGLGSQPLPVGAAQRVRHASERG 78
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,998,214
Number of Sequences: 37866
Number of extensions: 680993
Number of successful extensions: 2655
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 2593
Number of HSP's gapped (non-prelim): 72
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.