Guide to the Human Genome
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Search of human proteins with 40807471

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40807471 transcription termination factor, RNA polymerase II
[Homo sapiens]
         (1162 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40807471 transcription termination factor, RNA polymerase II ...  2325   0.0  
gi|21071052 helicase-like transcription factor [Homo sapiens]         257   4e-68
gi|21071054 helicase-like transcription factor [Homo sapiens]         257   4e-68
gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription facto...   174   6e-43
gi|6912622 RAD54 homolog B [Homo sapiens]                             173   7e-43
gi|164419749 SWI/SNF-related matrix-associated actin-dependent r...   168   3e-41
gi|58331268 excision repair protein ERCC6-like [Homo sapiens]         166   9e-41
gi|21071044 SWI/SNF-related matrix-associated actin-dependent re...   160   5e-39
gi|58219008 RAD26L hypothetical protein [Homo sapiens]                156   9e-38
gi|216548193 RAD54-like protein [Homo sapiens]                        153   8e-37
gi|216548186 RAD54-like protein [Homo sapiens]                        153   8e-37
gi|21071058 SWI/SNF-related matrix-associated actin-dependent re...   152   2e-36
gi|4557565 excision repair cross-complementing rodent repair def...   150   9e-36
gi|190358534 SWI/SNF-related, matrix-associated actin-dependent ...   149   2e-35
gi|21914927 helicase, lymphoid-specific [Homo sapiens]                148   3e-35
gi|190358536 SWI/SNF-related, matrix-associated actin-dependent ...   146   1e-34
gi|190358532 SWI/SNF-related, matrix-associated actin-dependent ...   146   1e-34
gi|118421089 chromodomain helicase DNA binding protein 2 isoform...   142   2e-33
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s...   136   1e-31
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...   134   4e-31
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa...   132   2e-30
gi|192807323 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|192807320 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|192807318 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|192807316 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|192807314 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|192807312 SWI/SNF-related matrix-associated actin-dependent r...   131   3e-30
gi|21071056 SWI/SNF-related matrix-associated actin-dependent re...   131   3e-30
gi|48255900 SWI/SNF-related matrix-associated actin-dependent re...   130   6e-30
gi|48255898 SWI/SNF-related matrix-associated actin-dependent re...   130   6e-30

>gi|40807471 transcription termination factor, RNA polymerase II [Homo
            sapiens]
          Length = 1162

 Score = 2325 bits (6025), Expect = 0.0
 Identities = 1162/1162 (100%), Positives = 1162/1162 (100%)

Query: 1    MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL 60
            MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL
Sbjct: 1    MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRADTCSFVRATDIPVSHCLLHEDFVVEL 60

Query: 61   QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN 120
            QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN
Sbjct: 61   QGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQDPDSKEHSVSNKSQHASETFHHSSN 120

Query: 121  WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS 180
            WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS
Sbjct: 121  WLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPEMMEKDLSS 180

Query: 181  GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS 240
            GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS
Sbjct: 181  GLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKS 240

Query: 241  SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS 300
            SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS
Sbjct: 241  SGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPS 300

Query: 301  IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV 360
            IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV
Sbjct: 301  IQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVV 360

Query: 361  FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ 420
            FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ
Sbjct: 361  FVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKKVEPSDPVARRVYLTTQ 420

Query: 421  LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT 480
            LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT
Sbjct: 421  LKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEKSNSQVPQQSHFT 480

Query: 481  KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS 540
            KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS
Sbjct: 481  KTTTGPPHLVPPQPLPRRGTQPVGSLELKSACQVTAGGSSQCYRGHTNQDHVHAVWKITS 540

Query: 541  EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL 600
            EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL
Sbjct: 541  EAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGL 600

Query: 601  GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV 660
            GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV
Sbjct: 601  GKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEV 660

Query: 661  EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE 720
            EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE
Sbjct: 661  EKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVE 720

Query: 721  GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL 780
            GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL
Sbjct: 721  GTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLL 780

Query: 781  KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF 840
            KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF
Sbjct: 781  KFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKF 840

Query: 841  QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP 900
            QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP
Sbjct: 841  QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP 900

Query: 901  RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL 960
            RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL
Sbjct: 901  RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTL 960

Query: 961  SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN 1020
            SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN
Sbjct: 961  SELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTN 1020

Query: 1021 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG 1080
            MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG
Sbjct: 1021 MLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGG 1080

Query: 1081 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV 1140
            NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV
Sbjct: 1081 NHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV 1140

Query: 1141 LSGSGESVTKLTLADLRVLFGI 1162
            LSGSGESVTKLTLADLRVLFGI
Sbjct: 1141 LSGSGESVTKLTLADLRVLFGI 1162


>gi|21071052 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score =  257 bits (657), Expect = 4e-68
 Identities = 175/580 (30%), Positives = 288/580 (49%), Gaps = 110/580 (18%)

Query: 618  KKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSN-KLRVYLYHG 676
            KK+  +K       SK    +     TLIICP S++ +W ++  + + S+  L  Y+Y+G
Sbjct: 452  KKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYG 511

Query: 677  PNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIIL 736
            P+R     +LS  DIV+TTY+++  +  T                  +PL  I W R+IL
Sbjct: 512  PDRIREPALLSKQDIVLTTYNILTHDYGTKGD---------------SPLHSIRWLRVIL 556

Query: 737  DEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRS 796
            DE H ++NP  Q + AV  L++  RW +TGTPIQN+L D++SLL FL+  PF +   W  
Sbjct: 557  DEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHR 616

Query: 797  QVDN----GSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEE 852
             +      G + G  RL  L K++ LRRTK      G+P++ LP+RK  + H+ LS++E 
Sbjct: 617  TIQRPVTMGDEGGLRRLQSLIKNITLRRTKTS-KIKGKPVLELPERKVFIQHITLSDEER 675

Query: 853  TVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSS 912
             +Y       R+ +  Y                          G+    +++        
Sbjct: 676  KIYQSVKNEGRATIGRYFNE-----------------------GTVLAHYAD-------- 704

Query: 913  TVHILSQLLRLRQCCCHLSLLKSALD---------PMELKGE-----GLVLSLEEQ---- 954
               +L  LLRLRQ CCH  LL +A+          P EL+ +      L+LS        
Sbjct: 705  ---VLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDEECA 761

Query: 955  --LSALTL----------------SELRDSEPSSTVSL------NGTFFKMELFEGMRES 990
              L +LT+                  +++ +P +   L           +    E  R+S
Sbjct: 762  ICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLECPPEELARDS 821

Query: 991  TK-----------ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATI 1039
             K           I++L+  L  +++ + + KS++VSQ+T  L ++ + LK  G  +  +
Sbjct: 822  EKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRL 881

Query: 1040 DGSVNPKQRMDLVEAFNHSR--GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQ 1097
            DGS+  K+R++ ++ F ++    P +ML+SL AGGVGLNL+  + +FL+D  WNP+ EDQ
Sbjct: 882  DGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQ 941

Query: 1098 ACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLA 1137
              DR +R+GQ+++V+I +F+ + +VEE +L++Q KK++LA
Sbjct: 942  CFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELA 981



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 33/113 (29%)

Query: 532 VHAVWKITSEAI----GQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQ 587
           VHA  ++T+E +     +L   L+    +T   E    ++ PLL HQKQALAW++ RE+ 
Sbjct: 199 VHAAVQMTTEQLKTEFDKLFEDLKE-DDKTHEMEPAEAIETPLLPHQKQALAWMVSRENS 257

Query: 588 KP----------------------------QGGILADDMGLGKTLTMIALILT 612
           K                              GGILADDMGLGKTLT IA+ILT
Sbjct: 258 KELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLGKTLTAIAVILT 310


>gi|21071054 helicase-like transcription factor [Homo sapiens]
          Length = 1009

 Score =  257 bits (657), Expect = 4e-68
 Identities = 175/580 (30%), Positives = 288/580 (49%), Gaps = 110/580 (18%)

Query: 618  KKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSN-KLRVYLYHG 676
            KK+  +K       SK    +     TLIICP S++ +W ++  + + S+  L  Y+Y+G
Sbjct: 452  KKKMLKKGACAVEGSKKTDVEERPRTTLIICPLSVLSNWIDQFGQHIKSDVHLNFYVYYG 511

Query: 677  PNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIIL 736
            P+R     +LS  DIV+TTY+++  +  T                  +PL  I W R+IL
Sbjct: 512  PDRIREPALLSKQDIVLTTYNILTHDYGTKGD---------------SPLHSIRWLRVIL 556

Query: 737  DEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRS 796
            DE H ++NP  Q + AV  L++  RW +TGTPIQN+L D++SLL FL+  PF +   W  
Sbjct: 557  DEGHAIRNPNAQQTKAVLDLESERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWHR 616

Query: 797  QVDN----GSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEE 852
             +      G + G  RL  L K++ LRRTK      G+P++ LP+RK  + H+ LS++E 
Sbjct: 617  TIQRPVTMGDEGGLRRLQSLIKNITLRRTKTS-KIKGKPVLELPERKVFIQHITLSDEER 675

Query: 853  TVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSS 912
             +Y       R+ +  Y                          G+    +++        
Sbjct: 676  KIYQSVKNEGRATIGRYFNE-----------------------GTVLAHYAD-------- 704

Query: 913  TVHILSQLLRLRQCCCHLSLLKSALD---------PMELKGE-----GLVLSLEEQ---- 954
               +L  LLRLRQ CCH  LL +A+          P EL+ +      L+LS        
Sbjct: 705  ---VLGLLLRLRQICCHTYLLTNAVSSNGPSGNDTPEELRKKLIRKMKLILSSGSDEECA 761

Query: 955  --LSALTL----------------SELRDSEPSSTVSL------NGTFFKMELFEGMRES 990
              L +LT+                  +++ +P +   L           +    E  R+S
Sbjct: 762  ICLDSLTVPVITHCAHVFCKPCICQVIQNEQPHAKCPLCRNDIHEDNLLECPPEELARDS 821

Query: 991  TK-----------ISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATI 1039
             K           I++L+  L  +++ + + KS++VSQ+T  L ++ + LK  G  +  +
Sbjct: 822  EKKSDMEWTSSSKINALMHALTDLRKKNPNIKSLVVSQFTTFLSLIEIPLKASGFVFTRL 881

Query: 1040 DGSVNPKQRMDLVEAFNHSR--GPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQ 1097
            DGS+  K+R++ ++ F ++    P +ML+SL AGGVGLNL+  + +FL+D  WNP+ EDQ
Sbjct: 882  DGSMAQKKRVESIQCFQNTEAGSPTIMLLSLKAGGVGLNLSAASRVFLMDPAWNPAAEDQ 941

Query: 1098 ACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLA 1137
              DR +R+GQ+++V+I +F+ + +VEE +L++Q KK++LA
Sbjct: 942  CFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNKKRELA 981



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 43/113 (38%), Positives = 56/113 (49%), Gaps = 33/113 (29%)

Query: 532 VHAVWKITSEAI----GQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQ 587
           VHA  ++T+E +     +L   L+    +T   E    ++ PLL HQKQALAW++ RE+ 
Sbjct: 199 VHAAVQMTTEQLKTEFDKLFEDLKE-DDKTHEMEPAEAIETPLLPHQKQALAWMVSRENS 257

Query: 588 KP----------------------------QGGILADDMGLGKTLTMIALILT 612
           K                              GGILADDMGLGKTLT IA+ILT
Sbjct: 258 KELPPFWEQRNDLYYNTITNFSEKDRPENVHGGILADDMGLGKTLTAIAVILT 310


>gi|27477070 BTAF1 RNA polymerase II, B-TFIID transcription
            factor-associated, 170kDa [Homo sapiens]
          Length = 1849

 Score =  174 bits (440), Expect = 6e-43
 Identities = 166/621 (26%), Positives = 270/621 (43%), Gaps = 104/621 (16%)

Query: 563  PAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEK 622
            P  +   L  +Q+  + WL +    K  G IL DDMGLGKTL  I ++        +E  
Sbjct: 1259 PVPINAELRKYQQDGVNWLAFLNKYKLHG-ILCDDMGLGKTLQSICILAGDHCHRAQEYA 1317

Query: 623  EKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSR 682
                A          +     +L++CP +L  HW +EV K  +   L    Y GP  + R
Sbjct: 1318 RSKLA----------ECMPLPSLVVCPPTLTGHWVDEVGKFCSREYLNPLHYTGPPTE-R 1366

Query: 683  ARV---LSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEA 739
             R+   +  +++++ +Y +V  +I   +                     I +   ILDE 
Sbjct: 1367 IRLQHQVKRHNLIVASYDVVRNDIDFFRN--------------------IKFNYCILDEG 1406

Query: 740  HNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQV- 798
            H +KN + + S AV +L A  R  ++GTPIQNN+L+++SL  FL          + ++  
Sbjct: 1407 HVIKNGKTKLSKAVKQLTANYRIILSGTPIQNNVLELWSLFDFLMPGFLGTERQFAARYG 1466

Query: 799  -------DNGSKKGGERLSILTKS--------LLLRRTKDQLDSTGRPLVILPQRKFQLH 843
                   D  S    +   +L            LLRR K+ +      L  LP +  Q +
Sbjct: 1467 KPILASRDARSSSREQEAGVLAMDALHRQVLPFLLRRMKEDV------LQDLPPKIIQDY 1520

Query: 844  HLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHS 903
            +  LS  +  +Y  F A+SR+                    +   S   L   +E+P+  
Sbjct: 1521 YCTLSPLQVQLYEDF-AKSRAKCDV----------------DETVSSATLSEETEKPK-- 1561

Query: 904  EAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSEL 963
                    +T H+   L  LR+ C H +L+ +   P E K     L+++        S L
Sbjct: 1562 ------LKATGHVFQALQYLRKLCNHPALVLTPQHP-EFKTTAEKLAVQN-------SSL 1607

Query: 964  RDSEPSSTVS-LNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNML 1022
             D + +  +S L        L  G    +   S++A+           + +I  Q  +ML
Sbjct: 1608 HDIQHAPKLSALKQLLLDCGLGNGSTSESGTESVVAQ----------HRILIFCQLKSML 1657

Query: 1023 KVVALHLKKHGL---TYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTG 1079
             +V   L K  L   TY  +DGS+ P QR  +V  FN+     V+L++   GG+GLNLTG
Sbjct: 1658 DIVEHDLLKPHLPSVTYLRLDGSIPPGQRHSIVSRFNNDPSIDVLLLTTHVGGLGLNLTG 1717

Query: 1080 GNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQ 1139
             + +  ++  WNP  + QA DR +R+GQ++ V ++R +  GT+EEKI+ LQ+ K ++A  
Sbjct: 1718 ADTVVFVEHDWNPMRDLQAMDRAHRIGQKRVVNVYRLITRGTLEEKIMGLQKFKMNIANT 1777

Query: 1140 VLSGSGESVTKLTLADLRVLF 1160
            V+S    S+  +    L  LF
Sbjct: 1778 VISQENSSLQSMGTDQLLDLF 1798


>gi|6912622 RAD54 homolog B [Homo sapiens]
          Length = 910

 Score =  173 bits (439), Expect = 7e-43
 Identities = 163/599 (27%), Positives = 258/599 (43%), Gaps = 121/599 (20%)

Query: 573  HQKQALAWL----LWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTAL 628
            HQK+ + +L    +        G ILAD+MGLGKTL  I+LI T + Q     K      
Sbjct: 299  HQKEGIIFLYECVMGMRMNGRCGAILADEMGLGKTLQCISLIWTLQCQGPYGGKP----- 353

Query: 629  TWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLST 688
                           TLI+ P SL+++WK E +K + S +++++     ++         
Sbjct: 354  -----------VIKKTLIVTPGSLVNNWKKEFQKWLGSERIKIFTVDQDHKVEEFIKSIF 402

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            Y ++I +Y ++ + +   K                     I +  +I DE H +KN  ++
Sbjct: 403  YSVLIISYEMLLRSLDQIKN--------------------IKFDLLICDEGHRLKNSAIK 442

Query: 749  TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRS------------ 796
            T+ A+  L    R  +TGTPIQN+L + ++L+ F+        + +R             
Sbjct: 443  TTTALISLSCEKRIILTGTPIQNDLQEFFALIDFVNPGILGSLSSYRKIYEEPIILSREP 502

Query: 797  QVDNGSKKGGER----LSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEE 852
                  K+ GER    L+ LT   +LRRT++ ++        LP +              
Sbjct: 503  SASEEEKELGERRAAELTCLTGLFILRRTQEIINK------YLPPK-------------- 542

Query: 853  TVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSS 912
             + NV F R   ALQ  L R         +  N+   R  L+   E   H          
Sbjct: 543  -IENVVFCRP-GALQIELYR---------KLLNSQVVRFCLQGLLENSPH---------- 581

Query: 913  TVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTV 972
                L  +  L++ C H  LL +++              E++ S+        S     +
Sbjct: 582  ----LICIGALKKLCNHPCLLFNSIK-------------EKECSSTCDKNEEKSLYKGLL 624

Query: 973  SLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKH 1032
            S+    +   LF   +ES K+  L   L  I     ++K V+VS +T  L ++    K+H
Sbjct: 625  SVFPADYNPLLFTE-KESGKLQVLSKLLAVIHELRPTEKVVLVSNYTQTLNILQEVCKRH 683

Query: 1033 GLTYATIDGSVNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWN 1091
            G  Y  +DG     QR  +V+ FN       + L+S  AGGVGLNL GG+HL L D+ WN
Sbjct: 684  GYAYTRLDGQTPISQRQQIVDGFNSQHSSFFIFLLSSKAGGVGLNLIGGSHLILYDIDWN 743

Query: 1092 PSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTK 1150
            P+ + QA  R++R GQ+  V I+R +  GT+EEKI Q Q     ++KQ L G+   +TK
Sbjct: 744  PATDIQAMSRVWRDGQKYPVHIYRLLTTGTIEEKIYQRQ-----ISKQGLCGAVVDLTK 797


>gi|164419749 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a1 isoform b [Homo sapiens]
          Length = 1042

 Score =  168 bits (425), Expect = 3e-41
 Identities = 155/584 (26%), Positives = 255/584 (43%), Gaps = 141/584 (24%)

Query: 569  PLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTAL 628
            PL  +Q + L WL+    +    GILAD+MGLGKTL  IAL+   K+             
Sbjct: 182  PLRDYQIRGLNWLI-SLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPH----- 235

Query: 629  TWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVL-- 686
                            +++ P S +H+W NE ++ V S  LRV  + G ++D+RA  +  
Sbjct: 236  ----------------MVLVPKSTLHNWMNEFKRWVPS--LRVICFVG-DKDARAAFIRD 276

Query: 687  ----STYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNV 742
                  +D+ +T+Y +V KE    K                    +  W  +++DEAH +
Sbjct: 277  EMMPGEWDVCVTSYEMVIKEKSVFK--------------------KFHWRYLVIDEAHRI 316

Query: 743  KNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPF---DEFNLWRSQVD 799
            KN + + S  V + ++  R  +TGTP+QNNL ++++LL FL    F   D+F+ W    +
Sbjct: 317  KNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKN 376

Query: 800  -NGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVF 858
              G +K  ERL  + K  LLRR K  ++ +      LP +K    +L LS+ +   Y   
Sbjct: 377  CLGDQKLVERLHAVLKPFLLRRIKTDVEKS------LPPKKEIKIYLGLSKMQREWYTKI 430

Query: 859  FARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILS 918
              +    L S                                       S +   + +L+
Sbjct: 431  LMKDIDVLNS---------------------------------------SGKMDKMRLLN 451

Query: 919  QLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTF 978
             L++LR+CC H  L   A +P      G   + +E +                VS +G  
Sbjct: 452  ILMQLRKCCNHPYLFDGA-EP------GPPYTTDEHI----------------VSNSG-- 486

Query: 979  FKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYAT 1038
                      +   +  LLA+L+         + +I SQ T +L ++  +    G  Y  
Sbjct: 487  ----------KMVVLDKLLAKLK-----EQGSRVLIFSQMTRLLDILEDYCMWRGYEYCR 531

Query: 1039 IDGSVNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQ 1097
            +DG    ++R + +EAFN     + + ++S  AGG+G+NL   + + L D  WNP ++ Q
Sbjct: 532  LDGQTPHEEREEAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVILYDSDWNPQVDLQ 591

Query: 1098 ACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
            A DR +R+GQ+K V + R + + TVEE+I++  E K  L   V+
Sbjct: 592  AMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVI 635


>gi|58331268 excision repair protein ERCC6-like [Homo sapiens]
          Length = 1250

 Score =  166 bits (421), Expect = 9e-41
 Identities = 164/612 (26%), Positives = 261/612 (42%), Gaps = 96/612 (15%)

Query: 570  LLLHQKQALAWL--LWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTA 627
            L  HQK+ +A+L  L+R+ +K  GGILADDMGLGKT+ +IA                   
Sbjct: 96   LFEHQKEGIAFLYSLYRDGRK--GGILADDMGLGKTVQIIA------------------- 134

Query: 628  LTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLS 687
              +LS        +H  L+I P +LI+ W  E  K      +RV  +HGP++D R R L+
Sbjct: 135  --FLSGMFDASLVNH-VLLIMPTNLINTWVKEFIKWTPG--MRVKTFHGPSKDERTRNLN 189

Query: 688  TYD----IVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVK 743
                   ++ITTY ++   I   +Q +   G                W  +ILDEAH +K
Sbjct: 190  RIQQRNGVIITTYQML---INNWQQLSSFRGQEF------------VWDYVILDEAHKIK 234

Query: 744  NPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSK 803
                +++I    + A  R  +TGTPIQNNL +++SL  F                  GS 
Sbjct: 235  TSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDF---------------ACQGSL 279

Query: 804  KGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSR 863
             G  +   +     + R +++  + G   +            K+SE+   +   +F R  
Sbjct: 280  LGTLKTFKMEYENPITRAREKDATPGEKAL----------GFKISENLMAIIKPYFLR-- 327

Query: 864  SALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRH-----------SEAADSPRSS 912
               +  +++ +S   ++  +  NP      E  S   ++            E       S
Sbjct: 328  -RTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVS 386

Query: 913  TVHILSQLLRLRQCCCHLSLLKSALD-PMELKGEGLVLSLEEQLSALTLSELRDSEPSST 971
              HI   L+  R     L +LK   D P  L      L     L   +  +  + E S  
Sbjct: 387  LDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLL---NLGTFSAQDGNEGEDSPD 443

Query: 972  VSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKK 1031
            V          L   M ES K+  L+  L+ ++      ++++ SQ   +L ++   LK 
Sbjct: 444  VDHIDQVTDDTL---MEESGKMIFLMDLLKRLR--DEGHQTLVFSQSRQILNIIERLLKN 498

Query: 1032 HGLTYATIDGSV-NPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHW 1090
                   IDG+V +  +R   +  F  ++   V L++   GGVGL LT    + + D  W
Sbjct: 499  RHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSW 558

Query: 1091 NPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTK 1150
            NP+ + QA DR+YR+GQ+++VV++R +  GTVEEKI + Q  K  L +Q           
Sbjct: 559  NPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRY 618

Query: 1151 LTLADLRVLFGI 1162
             +  +LR LF I
Sbjct: 619  FSKQELRELFTI 630


>gi|21071044 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a1 isoform a [Homo sapiens]
          Length = 1054

 Score =  160 bits (406), Expect = 5e-39
 Identities = 156/596 (26%), Positives = 255/596 (42%), Gaps = 153/596 (25%)

Query: 569  PLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTAL 628
            PL  +Q + L WL+    +    GILAD+MGLGKTL  IAL+   K+             
Sbjct: 182  PLRDYQIRGLNWLI-SLYENGVNGILADEMGLGKTLQTIALLGYLKHYRNIPGPH----- 235

Query: 629  TWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVL-- 686
                            +++ P S +H+W NE ++ V S  LRV  + G ++D+RA  +  
Sbjct: 236  ----------------MVLVPKSTLHNWMNEFKRWVPS--LRVICFVG-DKDARAAFIRD 276

Query: 687  ----STYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNV 742
                  +D+ +T+Y +V KE    K                    +  W  +++DEAH +
Sbjct: 277  EMMPGEWDVCVTSYEMVIKEKSVFK--------------------KFHWRYLVIDEAHRI 316

Query: 743  KNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPF---DEFNLWRSQVD 799
            KN + + S  V + ++  R  +TGTP+QNNL ++++LL FL    F   D+F+ W    +
Sbjct: 317  KNEKSKLSEIVREFKSTNRLLLTGTPLQNNLHELWALLNFLLPDVFNSADDFDSWFDTKN 376

Query: 800  -NGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVF 858
              G +K  ERL  + K  LLRR K  ++ +      LP +K    +L LS+ +   Y   
Sbjct: 377  CLGDQKLVERLHAVLKPFLLRRIKTDVEKS------LPPKKEIKIYLGLSKMQREWYTKI 430

Query: 859  FARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILS 918
              +    L S                                       S +   + +L+
Sbjct: 431  LMKDIDVLNS---------------------------------------SGKMDKMRLLN 451

Query: 919  QLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTF 978
             L++LR+CC H  L   A +P      G   + +E +                VS +G  
Sbjct: 452  ILMQLRKCCNHPYLFDGA-EP------GPPYTTDEHI----------------VSNSG-- 486

Query: 979  FKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYAT 1038
                      +   +  LLA+L+         + +I SQ T +L ++  +    G  Y  
Sbjct: 487  ----------KMVVLDKLLAKLK-----EQGSRVLIFSQMTRLLDILEDYCMWRGYEYCR 531

Query: 1039 IDGSVNPKQRMD------------LVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFL 1085
            +DG    ++R D             +EAFN     + + ++S  AGG+G+NL   + + L
Sbjct: 532  LDGQTPHEEREDKFLEVEFLGQREAIEAFNAPNSSKFIFMLSTRAGGLGINLASADVVIL 591

Query: 1086 LDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             D  WNP ++ QA DR +R+GQ+K V + R + + TVEE+I++  E K  L   V+
Sbjct: 592  YDSDWNPQVDLQAMDRAHRIGQKKPVRVFRLITDNTVEERIVERAEIKLRLDSIVI 647


>gi|58219008 RAD26L hypothetical protein [Homo sapiens]
          Length = 712

 Score =  156 bits (395), Expect = 9e-38
 Identities = 150/576 (26%), Positives = 264/576 (45%), Gaps = 82/576 (14%)

Query: 591  GGILADDMGLGKTLTMI---ALILTQKN-QEKKEEKEKSTALTWLSKDDSCDFTSHGTLI 646
            G IL DDMGLGKT+ +I   A +L +K  +E  E       L  + K+          LI
Sbjct: 154  GCILGDDMGLGKTVQVISFLAAVLHKKGTREDIENNMPEFLLRSMKKEPLSSTAKKMFLI 213

Query: 647  ICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRA-RVLSTY-DIVITTYSLVAKEIP 704
            + P S++++WK+E++        RV + HG  +D+   RV     +I +TTY  +   + 
Sbjct: 214  VAPLSVLYNWKDELD---TWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLRLCLD 270

Query: 705  TNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAV 764
                                 L  + W+ +I+DEAH +KNP+ + +  +  L+   R  +
Sbjct: 271  E--------------------LNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGL 310

Query: 765  TGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQ----VDNGSK------------KGGER 808
            TGT +QNN+ +++ ++ +           ++ Q    V++G +            K  +R
Sbjct: 311  TGTILQNNMKELWCVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQR 370

Query: 809  LSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQS 868
            L+       LRRTK  +         LP+++ ++ +  L++ ++ VY          L  
Sbjct: 371  LAKKMSGWFLRRTKTLIKDQ------LPKKEDRMVYCSLTDFQKAVYQTVLETEDVTL-- 422

Query: 869  YLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCC 928
             L+  E    +SG+   N   +           H E        T++ LS L  L++   
Sbjct: 423  ILQSSEPCTCRSGQKRRNCCYKTN--------SHGETV-----KTLY-LSYLTVLQKVAN 468

Query: 929  HLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMR 988
            H++LL++A    +   E L+  + +Q+ +     ++ S+ ++           E     +
Sbjct: 469  HVALLQAASTSKQQ--ETLIKRICDQVFSRFPDFVQKSKDAA----------FETLSDPK 516

Query: 989  ESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQR 1048
             S K+  L   L   ++N    K ++ S  T +L V+  +    GL Y  +DGS   ++R
Sbjct: 517  YSGKMKVLQQLLNHCRKNR--DKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEER 574

Query: 1049 MDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQ 1108
            + +V+ FN ++   + L+S +AGG+GLN  G N + L D  WNP+ + QA DR YR+GQ 
Sbjct: 575  LKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQC 634

Query: 1109 KDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGS 1144
            +DV + R +  GTVEE I+ L++  K     V+ GS
Sbjct: 635  RDVKVLRLISLGTVEE-IMYLRQIYKQQLHCVVVGS 669


>gi|216548193 RAD54-like protein [Homo sapiens]
          Length = 747

 Score =  153 bits (387), Expect = 8e-37
 Identities = 171/655 (26%), Positives = 273/655 (41%), Gaps = 159/655 (24%)

Query: 545  QLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLW-----RESQKPQGGILADDMG 599
            QL    E  P   VV  DP   KV L  HQ++ + +L W     R      G I+AD+MG
Sbjct: 131  QLKLDKEKLPVHVVV--DPILSKV-LRPHQREGVKFL-WECVTSRRIPGSHGCIMADEMG 186

Query: 600  LGKTLTMIALILT--QKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWK 657
            LGKTL  I L+ T  +++ E K E +K+                   +++ P+SL+ +W 
Sbjct: 187  LGKTLQCITLMWTLLRQSPECKPEIDKA-------------------VVVSPSSLVKNWY 227

Query: 658  NEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANL 717
            NEV K +   +++     G ++D   + L  +                N++ A +     
Sbjct: 228  NEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGF---------------MNQRGARV----- 266

Query: 718  NVEGTSTPLLRIAWAR---------------IILDEAHNVKNPRVQTSIAVCKLQACARW 762
                 S+P+L I++                 +I DE H +KN   QT  A+  L    R 
Sbjct: 267  -----SSPILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRV 321

Query: 763  AVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGG-------------ERL 809
             ++GTPIQN+LL+ +SL+ F+        + ++   +    KG              ERL
Sbjct: 322  LISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERL 381

Query: 810  SILTKSL---LLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSAL 866
              LT  +   L+RRT D L         LP +  Q+   +L+  +  +Y  F  +++ A 
Sbjct: 382  RELTSIVNRCLIRRTSDILSK------YLPVKIEQVVCCRLTPLQTELYKRFLRQAKPA- 434

Query: 867  QSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQC 926
                                                 E  +   S  V  LS +  L++ 
Sbjct: 435  ------------------------------------EELLEGKMS--VSSLSSITSLKKL 456

Query: 927  CCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEG 986
            C H +L+    D    + +G V        AL L     S  +    L+G    ++    
Sbjct: 457  CNHPALI---YDKCVEEEDGFV-------GALDLFPPGYSSKALEPQLSGKMLVLDY--- 503

Query: 987  MRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPK 1046
                         + A+ R+ +S K V+VS +T  L +     +     Y  +DG+++ K
Sbjct: 504  -------------ILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIK 550

Query: 1047 QRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRV 1105
            +R  +VE FN    P  V ++S  AGG GLNL G N L + D  WNP+ ++QA  R++R 
Sbjct: 551  KRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRD 610

Query: 1106 GQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLF 1160
            GQ+K   I+R +  GT+EEKI Q Q  KK L+  V+    +     +L +L+ LF
Sbjct: 611  GQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELF 665


>gi|216548186 RAD54-like protein [Homo sapiens]
          Length = 747

 Score =  153 bits (387), Expect = 8e-37
 Identities = 171/655 (26%), Positives = 273/655 (41%), Gaps = 159/655 (24%)

Query: 545  QLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLW-----RESQKPQGGILADDMG 599
            QL    E  P   VV  DP   KV L  HQ++ + +L W     R      G I+AD+MG
Sbjct: 131  QLKLDKEKLPVHVVV--DPILSKV-LRPHQREGVKFL-WECVTSRRIPGSHGCIMADEMG 186

Query: 600  LGKTLTMIALILT--QKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWK 657
            LGKTL  I L+ T  +++ E K E +K+                   +++ P+SL+ +W 
Sbjct: 187  LGKTLQCITLMWTLLRQSPECKPEIDKA-------------------VVVSPSSLVKNWY 227

Query: 658  NEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGANL 717
            NEV K +   +++     G ++D   + L  +                N++ A +     
Sbjct: 228  NEVGKWLGG-RIQPLAIDGGSKDEIDQKLEGF---------------MNQRGARV----- 266

Query: 718  NVEGTSTPLLRIAWAR---------------IILDEAHNVKNPRVQTSIAVCKLQACARW 762
                 S+P+L I++                 +I DE H +KN   QT  A+  L    R 
Sbjct: 267  -----SSPILIISYETFRLHVGVLQKGSVGLVICDEGHRLKNSENQTYQALDSLNTSRRV 321

Query: 763  AVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGG-------------ERL 809
             ++GTPIQN+LL+ +SL+ F+        + ++   +    KG              ERL
Sbjct: 322  LISGTPIQNDLLEYFSLVHFVNSGILGTAHEFKKHFELPILKGRDAAASEADRQLGEERL 381

Query: 810  SILTKSL---LLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSAL 866
              LT  +   L+RRT D L         LP +  Q+   +L+  +  +Y  F  +++ A 
Sbjct: 382  RELTSIVNRCLIRRTSDILSK------YLPVKIEQVVCCRLTPLQTELYKRFLRQAKPA- 434

Query: 867  QSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQC 926
                                                 E  +   S  V  LS +  L++ 
Sbjct: 435  ------------------------------------EELLEGKMS--VSSLSSITSLKKL 456

Query: 927  CCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEG 986
            C H +L+    D    + +G V        AL L     S  +    L+G    ++    
Sbjct: 457  CNHPALI---YDKCVEEEDGFV-------GALDLFPPGYSSKALEPQLSGKMLVLDY--- 503

Query: 987  MRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPK 1046
                         + A+ R+ +S K V+VS +T  L +     +     Y  +DG+++ K
Sbjct: 504  -------------ILAVTRSRSSDKVVLVSNYTQTLDLFEKLCRARRYLYVRLDGTMSIK 550

Query: 1047 QRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRV 1105
            +R  +VE FN    P  V ++S  AGG GLNL G N L + D  WNP+ ++QA  R++R 
Sbjct: 551  KRAKVVERFNSPSSPDFVFMLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRD 610

Query: 1106 GQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLF 1160
            GQ+K   I+R +  GT+EEKI Q Q  KK L+  V+    +     +L +L+ LF
Sbjct: 611  GQKKTCYIYRLLSAGTIEEKIFQRQSHKKALSSCVVDEEQDVERHFSLGELKELF 665


>gi|21071058 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a5 [Homo sapiens]
          Length = 1052

 Score =  152 bits (384), Expect = 2e-36
 Identities = 145/580 (25%), Positives = 238/580 (41%), Gaps = 141/580 (24%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+    +    GILAD+MGLGKTL  I+L+   K+                 
Sbjct: 183  YQVRGLNWLI-SLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPH--------- 232

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLST---- 688
                        +++ P S +H+W +E ++ V +  LR     G      A V       
Sbjct: 233  ------------MVLVPKSTLHNWMSEFKRWVPT--LRSVCLIGDKEQRAAFVRDVLLPG 278

Query: 689  -YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRV 747
             +D+ +T+Y ++ KE    K                    +  W  +++DEAH +KN + 
Sbjct: 279  EWDVCVTSYEMLIKEKSVFK--------------------KFNWRYLVIDEAHRIKNEKS 318

Query: 748  QTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPF---DEFNLWRSQVDN--GS 802
            + S  V + +   R  +TGTP+QNNL +++SLL FL    F   D+F+ W    +N  G 
Sbjct: 319  KLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVFNSADDFDSW-FDTNNCLGD 377

Query: 803  KKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS 862
            +K  ERL ++ +  LLRR K  ++ +      LP +K    ++ LS+ +   Y     + 
Sbjct: 378  QKLVERLHMVLRPFLLRRIKADVEKS------LPPKKEVKIYVGLSKMQREWYTRILMKD 431

Query: 863  RSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
               L S  K  + R                                       +L+ L++
Sbjct: 432  IDILNSAGKMDKMR---------------------------------------LLNILMQ 452

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+CC H  L   A                              EP    + +     M 
Sbjct: 453  LRKCCNHPYLFDGA------------------------------EPGPPYTTD-----MH 477

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L     +   +  LL +L+         + +I SQ T +L ++  +       Y  +DG 
Sbjct: 478  LVTNSGKMVVLDKLLPKLK-----EQGSRVLIFSQMTRVLDILEDYCMWRNYEYCRLDGQ 532

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
                +R D + A+N     + V ++S  AGG+G+NL   + + L D  WNP ++ QA DR
Sbjct: 533  TPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINLATADVVILYDSDWNPQVDLQAMDR 592

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQ K V + RF+ + TVEE+I++  E K  L   V+
Sbjct: 593  AHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVI 632


>gi|4557565 excision repair cross-complementing rodent repair
            deficiency, complementation group 6 [Homo sapiens]
          Length = 1493

 Score =  150 bits (378), Expect = 9e-36
 Identities = 144/611 (23%), Positives = 245/611 (40%), Gaps = 143/611 (23%)

Query: 560  AEDPAGLKVP------LLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQ 613
            AE   G KVP      L  +Q+  + WL W    +  GGIL D+MGLGKT+ +IA +   
Sbjct: 491  AEFDEGFKVPGFLFKKLFKYQQTGVRWL-WELHCQQAGGILGDEMGLGKTIQIIAFLAGL 549

Query: 614  KNQEKKEEKEKSTALTWLSKDDSCDFTSHG-TLIICPASLIHHWKNEVEKRVNSNKLRVY 672
               + +            ++  +  F   G T+I+CP +++H W  E        ++ + 
Sbjct: 550  SYSKIR------------TRGSNYRFEGLGPTVIVCPTTVMHQWVKEFHTWWPPFRVAIL 597

Query: 673  LYHGPNRDSRARVLST----YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLR 728
               G     + +++      + I+IT+YS +                          + R
Sbjct: 598  HETGSYTHKKEKLIRDVAHCHGILITSYSYIRL--------------------MQDDISR 637

Query: 729  IAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPF 788
              W  +ILDE H ++NP    ++A  + +   R  ++G+P+QNNL +++SL  F+     
Sbjct: 638  YDWHYVILDEGHKIRNPNAAVTLACKQFRTPHRIILSGSPMQNNLRELWSLFDFIFPGKL 697

Query: 789  DEFNLWRSQ----VDNGSKKGGERLSILT------------KSLLLRRTKDQLDSTGRPL 832
                ++  Q    +  G       + + T               LLRR K  +  +    
Sbjct: 698  GTLPVFMEQFSVPITMGGYSNASPVQVKTAYKCACVLRDTINPYLLRRMKSDVKMS---- 753

Query: 833  VILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVA 892
            + LP +  Q+   +L++++  VY           Q+++   E     +G           
Sbjct: 754  LSLPDKNEQVLFCRLTDEQHKVY-----------QNFVDSKEVYRILNGE---------- 792

Query: 893  LEFGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLE 952
                                 + I S L+ LR+ C H  L      P  LKG        
Sbjct: 793  ---------------------MQIFSGLIALRKICNHPDLFSGG--PKNLKG-------- 821

Query: 953  EQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQR--NSASQ 1010
                      L D E               L E      K S  +  +E++ +  +   Q
Sbjct: 822  ----------LPDDE---------------LEEDQFGYWKRSGKMIVVESLLKIWHKQGQ 856

Query: 1011 KSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLA 1070
            + ++ SQ   ML ++ + L+    TY  +DG+     R  L+  +N      V L++   
Sbjct: 857  RVLLFSQSRQMLDILEVFLRAQKYTYLKMDGTTTIASRQPLITRYNEDTSIFVFLLTTRV 916

Query: 1071 GGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQ 1130
            GG+G+NLTG N + + D  WNPS + QA +R +R+GQ+K V ++R +  GT+EEKI   Q
Sbjct: 917  GGLGVNLTGANRVVIYDPDWNPSTDTQARERAWRIGQKKQVTVYRLLTAGTIEEKIYHRQ 976

Query: 1131 EKKKDLAKQVL 1141
              K+ L  +VL
Sbjct: 977  IFKQFLTNRVL 987


>gi|190358534 SWI/SNF-related, matrix-associated actin-dependent
            regulator of chromatin, subfamily a, containing DEAD/H
            box 1 isoform b [Homo sapiens]
          Length = 1026

 Score =  149 bits (375), Expect = 2e-35
 Identities = 155/602 (25%), Positives = 260/602 (43%), Gaps = 108/602 (17%)

Query: 561  EDPAGLKVPLLL--HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEK 618
            E P+ L   L L  +QK  L WL          GILAD+MGLGKT+  IA          
Sbjct: 486  EQPSILNQSLSLKPYQKVGLNWLALVHKHG-LNGILADEMGLGKTIQAIAF--------- 535

Query: 619  KEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPN 678
                     L +L ++ +    +   LI+ PAS I +W  EV     +  L+V  Y+G +
Sbjct: 536  ---------LAYLYQEGN----NGPHLIVVPASTIDNWLREVNLWCPT--LKVLCYYG-S 579

Query: 679  RDSRARV-------LSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAW 731
            ++ R ++          Y++++TTY+     I ++   +      LN             
Sbjct: 580  QEERKQIRFNIHSRYEDYNVIVTTYNCA---ISSSDDRSLFRRLKLNYA----------- 625

Query: 732  ARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEF 791
               I DE H +KN        +  + A  R  +TGTP+QNNLL++ SLL F+    F   
Sbjct: 626  ---IFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSS 682

Query: 792  NLWRSQVDNGSKKGGERLSI-----------LTKSLLLRRTKDQLDSTGRPLVILPQRKF 840
                 ++ +   K  +  SI           + K  +LRR K+++      L  LP +K 
Sbjct: 683  TSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEV------LKQLPPKKD 736

Query: 841  QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRG--NQSGRSPNNPFSRVALEFGSE 898
            ++    +SE +E +Y   F R + ++ +  K  E      Q  +  N+P           
Sbjct: 737  RIELCAMSEKQEQLYLGLFNRLKKSINNLEKNTEMCNVMMQLRKMANHPLLH-------- 788

Query: 899  EPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSAL 958
              R    A+  +      +SQL+      C  +         +L  E + +  + +L  L
Sbjct: 789  --RQYYTAEKLKE-----MSQLMLKEPTHCEAN--------PDLIFEDMEVMTDFELHVL 833

Query: 959  TLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQW 1018
                           +N     M+L     +   +  +L+EL+         + V+ SQ+
Sbjct: 834  CKQYRH---------INNFQLDMDLILDSGKFRVLGCILSELK-----QKGDRVVLFSQF 879

Query: 1019 TNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLT 1078
            T ML ++ + LK H   Y  +DG     +R+ L++ FN      V L+S  AGG+G+NLT
Sbjct: 880  TMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGINLT 939

Query: 1079 GGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAK 1138
              N + L D+  NP  + QA DR +RVGQ K+V++ + + +GT+EE +L++ ++K  L +
Sbjct: 940  SANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKLEQ 999

Query: 1139 QV 1140
             +
Sbjct: 1000 DM 1001


>gi|21914927 helicase, lymphoid-specific [Homo sapiens]
          Length = 838

 Score =  148 bits (373), Expect = 3e-35
 Identities = 149/638 (23%), Positives = 263/638 (41%), Gaps = 138/638 (21%)

Query: 550  LESCPGETVVAEDPAGLKVPLLL-HQKQALAWL--LWRESQKPQGGILADDMGLGKTLTM 606
            +  C G+ V  + P      ++  +Q + + WL  LW        GILAD+MGLGKT+  
Sbjct: 202  VRKCNGQPVPFQQPKHFTGGVMRWYQVEGMEWLRMLWENGIN---GILADEMGLGKTVQC 258

Query: 607  IALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIIC-PASLIHHWKNEVEKRVN 665
            IA I     +                          G  ++C P S + +W  E ++   
Sbjct: 259  IATIALMIQRGVP-----------------------GPFLVCGPLSTLPNWMAEFKRFTP 295

Query: 666  SNKLRVYLYHGPNRD---------SRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGAN 716
               +   LYHG   +          R   L  + +VIT++ +  ++              
Sbjct: 296  D--IPTMLYHGTQEERQKLVRNIYKRKGTLQIHPVVITSFEIAMRD-------------- 339

Query: 717  LNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDM 776
                     L    W  +I+DE H +KN + +    + +  A  +  +TGTP+QNNL ++
Sbjct: 340  ------RNALQHCYWKYLIVDEGHRIKNMKCRLIRELKRFNADNKLLLTGTPLQNNLSEL 393

Query: 777  YSLLKFLRCSPFDEFNLWRSQVDNGSKK-------GGER-------LSILTKSLLLRRTK 822
            +SLL FL    FD+   + S  D  S           ER       L  +    LLRR K
Sbjct: 394  WSLLNFLLPDVFDDLKSFESWFDITSLSETAEDIIAKEREQNVLHMLHQILTPFLLRRLK 453

Query: 823  DQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGR 882
              +      L + P+R+  ++   LS+ +E  Y     R+ + +    ++     + +GR
Sbjct: 454  SDV-----ALEVPPKREVVVY-APLSKKQEIFYTAIVNRTIANMFGSSEKETIELSPTGR 507

Query: 883  SPN---------------NPFSRVALEFGSEEPRHSEAADS--PRSSTVHILSQ--LLRL 923
                              N   ++  +   E  R     +   P  S V++  Q  ++ L
Sbjct: 508  PKRRTRKSINYSKIDDFPNELEKLISQIQPEVDRERAVVEVNIPVESEVNLKLQNIMMLL 567

Query: 924  RQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMEL 983
            R+CC H  L++  +DP+  +       ++E+L                V+ +G F  ++ 
Sbjct: 568  RKCCNHPYLIEYPIDPVTQE-----FKIDEEL----------------VTNSGKFLILD- 605

Query: 984  FEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSV 1043
                        +L EL+         K ++ SQ T+ML ++  +       ++ +DGS+
Sbjct: 606  -----------RMLPELK-----KRGHKVLLFSQMTSMLDILMDYCHLRDFNFSRLDGSM 649

Query: 1044 NPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIY 1103
            +  +R   + +FN      + L+S  AGG+G+NLT  + + + D  WNP  + QA DR +
Sbjct: 650  SYSEREKNMHSFNTDPEVFIFLVSTRAGGLGINLTAADTVIIYDSDWNPQSDLQAQDRCH 709

Query: 1104 RVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
            R+GQ K VV++R V   T+++KI++    K+ L K ++
Sbjct: 710  RIGQTKPVVVYRLVTANTIDQKIVERAAAKRKLEKLII 747


>gi|190358536 SWI/SNF-related, matrix-associated actin-dependent
            regulator of chromatin, subfamily a, containing DEAD/H
            box 1 isoform a [Homo sapiens]
          Length = 1028

 Score =  146 bits (369), Expect = 1e-34
 Identities = 153/604 (25%), Positives = 260/604 (43%), Gaps = 110/604 (18%)

Query: 561  EDPAGLKVPLLL--HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEK 618
            E P+ L   L L  +QK  L WL          GILAD+MGLGKT+  IA          
Sbjct: 486  EQPSILNQSLSLKPYQKVGLNWLALVHKHG-LNGILADEMGLGKTIQAIAF--------- 535

Query: 619  KEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPN 678
                     L +L ++ +    +   LI+ PAS I +W  EV     +  L+V  Y+G +
Sbjct: 536  ---------LAYLYQEGN----NGPHLIVVPASTIDNWLREVNLWCPT--LKVLCYYG-S 579

Query: 679  RDSRARV-------LSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAW 731
            ++ R ++          Y++++TTY+     I ++   +      LN             
Sbjct: 580  QEERKQIRFNIHSRYEDYNVIVTTYNCA---ISSSDDRSLFRRLKLNYA----------- 625

Query: 732  ARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEF 791
               I DE H +KN        +  + A  R  +TGTP+QNNLL++ SLL F+    F   
Sbjct: 626  ---IFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSS 682

Query: 792  NLWRSQVDNGSKKGGERLSI-----------LTKSLLLRRTKDQLDSTGRPLVILPQRKF 840
                 ++ +   K  +  SI           + K  +LRR K+++      L  LP +K 
Sbjct: 683  TSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEV------LKQLPPKKD 736

Query: 841  QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRG----NQSGRSPNNPFSRVALEFG 896
            ++    +SE +E +Y   F R + ++ + +    +       Q  +  N+P         
Sbjct: 737  RIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLH------ 790

Query: 897  SEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLS 956
                R    A+  +      +SQL+      C  +         +L  E + +  + +L 
Sbjct: 791  ----RQYYTAEKLKE-----MSQLMLKEPTHCEAN--------PDLIFEDMEVMTDFELH 833

Query: 957  ALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVS 1016
             L               +N     M+L     +   +  +L+EL+         + V+ S
Sbjct: 834  VLCKQYRH---------INNFQLDMDLILDSGKFRVLGCILSELK-----QKGDRVVLFS 879

Query: 1017 QWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLN 1076
            Q+T ML ++ + LK H   Y  +DG     +R+ L++ FN      V L+S  AGG+G+N
Sbjct: 880  QFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGIN 939

Query: 1077 LTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDL 1136
            LT  N + L D+  NP  + QA DR +RVGQ K+V++ + + +GT+EE +L++ ++K  L
Sbjct: 940  LTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKL 999

Query: 1137 AKQV 1140
             + +
Sbjct: 1000 EQDM 1003


>gi|190358532 SWI/SNF-related, matrix-associated actin-dependent
            regulator of chromatin, subfamily a, containing DEAD/H
            box 1 isoform a [Homo sapiens]
          Length = 1028

 Score =  146 bits (369), Expect = 1e-34
 Identities = 153/604 (25%), Positives = 260/604 (43%), Gaps = 110/604 (18%)

Query: 561  EDPAGLKVPLLL--HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEK 618
            E P+ L   L L  +QK  L WL          GILAD+MGLGKT+  IA          
Sbjct: 486  EQPSILNQSLSLKPYQKVGLNWLALVHKHG-LNGILADEMGLGKTIQAIAF--------- 535

Query: 619  KEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPN 678
                     L +L ++ +    +   LI+ PAS I +W  EV     +  L+V  Y+G +
Sbjct: 536  ---------LAYLYQEGN----NGPHLIVVPASTIDNWLREVNLWCPT--LKVLCYYG-S 579

Query: 679  RDSRARV-------LSTYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAW 731
            ++ R ++          Y++++TTY+     I ++   +      LN             
Sbjct: 580  QEERKQIRFNIHSRYEDYNVIVTTYNCA---ISSSDDRSLFRRLKLNYA----------- 625

Query: 732  ARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEF 791
               I DE H +KN        +  + A  R  +TGTP+QNNLL++ SLL F+    F   
Sbjct: 626  ---IFDEGHMLKNMGSIRYQHLMTINANNRLLLTGTPVQNNLLELMSLLNFVMPHMFSSS 682

Query: 792  NLWRSQVDNGSKKGGERLSI-----------LTKSLLLRRTKDQLDSTGRPLVILPQRKF 840
                 ++ +   K  +  SI           + K  +LRR K+++      L  LP +K 
Sbjct: 683  TSEIRRMFSSKTKSADEQSIYEKERIAHAKQIIKPFILRRVKEEV------LKQLPPKKD 736

Query: 841  QLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRG----NQSGRSPNNPFSRVALEFG 896
            ++    +SE +E +Y   F R + ++ + +    +       Q  +  N+P         
Sbjct: 737  RIELCAMSEKQEQLYLGLFNRLKKSINNLVTEKNTEMCNVMMQLRKMANHPLLH------ 790

Query: 897  SEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLS 956
                R    A+  +      +SQL+      C  +         +L  E + +  + +L 
Sbjct: 791  ----RQYYTAEKLKE-----MSQLMLKEPTHCEAN--------PDLIFEDMEVMTDFELH 833

Query: 957  ALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVS 1016
             L               +N     M+L     +   +  +L+EL+         + V+ S
Sbjct: 834  VLCKQYRH---------INNFQLDMDLILDSGKFRVLGCILSELK-----QKGDRVVLFS 879

Query: 1017 QWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQVMLISLLAGGVGLN 1076
            Q+T ML ++ + LK H   Y  +DG     +R+ L++ FN      V L+S  AGG+G+N
Sbjct: 880  QFTMMLDILEVLLKHHQHRYLRLDGKTQISERIHLIDEFNTDMDIFVFLLSTKAGGLGIN 939

Query: 1077 LTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDL 1136
            LT  N + L D+  NP  + QA DR +RVGQ K+V++ + + +GT+EE +L++ ++K  L
Sbjct: 940  LTSANVVILHDIDCNPYNDKQAEDRCHRVGQTKEVLVIKLISQGTIEESMLKINQQKLKL 999

Query: 1137 AKQV 1140
             + +
Sbjct: 1000 EQDM 1003


>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
            [Homo sapiens]
          Length = 1828

 Score =  142 bits (357), Expect = 2e-33
 Identities = 147/608 (24%), Positives = 249/608 (40%), Gaps = 140/608 (23%)

Query: 548  RSLESCPGETVVAEDPA---GLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTL 604
            ++L+  P    + + PA   G  + L  +Q + L WL      K    ILAD+MGLGKT+
Sbjct: 459  KALKQRPRFVALKKQPAYLGGENLELRDYQLEGLNWLA-HSWCKNNSVILADEMGLGKTI 517

Query: 605  TMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGT-LIICPASLIHHWKNEVEKR 663
              I+ +    +Q +                       +G  LI+ P S +  W+ E E  
Sbjct: 518  QTISFLSYLFHQHQL----------------------YGPFLIVVPLSTLTSWQREFEIW 555

Query: 664  VNSNKLRVYLYHGPNRD---------SRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPG 714
                 + VY+    +R+         S+ + L  ++ +ITTY ++ K+            
Sbjct: 556  APEINVVVYIGDLMSRNTIREYEWIHSQTKRLK-FNALITTYEILLKD------------ 602

Query: 715  ANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLL 774
                     T L  I WA + +DEAH +KN        +   ++  R  +TGTP+QN+L 
Sbjct: 603  --------KTVLGSINWAFLGVDEAHRLKNDDSLLYKTLIDFKSNHRLLITGTPLQNSLK 654

Query: 775  DMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVI 834
            +++SLL F+    F+ +  +      G + G + L  + +  LLRR K  ++ +      
Sbjct: 655  ELWSLLHFIMPEKFEFWEDFEEDHGKGRENGYQSLHKVLEPFLLRRVKKDVEKS------ 708

Query: 835  LPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALE 894
            LP +  Q+  +++S  ++  Y     R+  AL                            
Sbjct: 709  LPAKVEQILRVEMSALQKQYYKWILTRNYKAL---------------------------- 740

Query: 895  FGSEEPRHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQ 954
                       A   R ST   L+ ++ L++CC H  L+K   +     G+ ++LSL   
Sbjct: 741  -----------AKGTRGSTSGFLNIVMELKKCCNHCYLIKPPEENERENGQEILLSLIRS 789

Query: 955  LSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVI 1014
               L L +                   +L   +RE                     + +I
Sbjct: 790  SGKLILLD-------------------KLLTRLRER------------------GNRVLI 812

Query: 1015 VSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHSRGPQV-MLISLLAGGV 1073
             SQ   ML ++A +L      +  +DGS+  + R   ++ FN         L+S  AGG+
Sbjct: 813  FSQMVRMLDILAEYLTIKHYPFQRLDGSIKGEIRKQALDHFNADGSEDFCFLLSTRAGGL 872

Query: 1074 GLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKK 1133
            G+NL   + + + D  WNP  + QA  R +R+GQ+K V I+R V +GTVEE+I++  +KK
Sbjct: 873  GINLASADTVVIFDSDWNPQNDLQAQARAHRIGQKKQVNIYRLVTKGTVEEEIIERAKKK 932

Query: 1134 KDLAKQVL 1141
              L   V+
Sbjct: 933  MVLDHLVI 940


>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
            sapiens]
          Length = 2302

 Score =  136 bits (342), Expect = 1e-31
 Identities = 143/599 (23%), Positives = 243/599 (40%), Gaps = 141/599 (23%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + + WLL+    + Q  ILAD+MGLGKT+  IA +    N                 
Sbjct: 535  YQLEGVNWLLFNWYNR-QNCILADEMGLGKTIQSIAFLQEVYN----------------- 576

Query: 633  KDDSCDFTSHGT-LIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPN------------- 678
                     HG  L+I P S I +W+ E       N +   +YHG               
Sbjct: 577  ------VGIHGPFLVIAPLSTITNWEREFNTWTEMNTI---VYHGSLASRQMIQQYEMYC 627

Query: 679  RDSRARVLS---TYDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARII 735
            +DSR R++     +D +ITT+ ++  + P                     L  I W  +I
Sbjct: 628  KDSRGRLIPGAYKFDALITTFEMILSDCPE--------------------LREIEWRCVI 667

Query: 736  LDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPF-DEFNLW 794
            +DEAH +KN   +   ++  +    +  +TGTP+QN + +++SLL FL  S F  E    
Sbjct: 668  IDEAHRLKNRNCKLLDSLKHMDLEHKVLLTGTPLQNTVEELFSLLHFLEPSQFPSESEFL 727

Query: 795  RSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETV 854
            +   D  +++  ++L  + K ++LRR K+ ++    P      ++  +  ++L+  ++  
Sbjct: 728  KDFGDLKTEEQVQKLQAILKPMMLRRLKEDVEKNLAP------KQETIIEVELTNIQKKY 781

Query: 855  YNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTV 914
            Y     ++ S L        S+G      PN                             
Sbjct: 782  YRAILEKNFSFL--------SKGAGHTNMPN----------------------------- 804

Query: 915  HILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSL 974
             +L+ ++ LR+CC H  L+  A               EE++    L+E R++       +
Sbjct: 805  -LLNTMMELRKCCNHPYLINGA---------------EEKI----LTEFREA----CHII 840

Query: 975  NGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGL 1034
               F    +     +   I  LL +L+A        K +I SQ    L ++  +L +   
Sbjct: 841  PHDFHLQAMVRSAGKLVLIDKLLPKLKA-----GGHKVLIFSQMVRCLDILEDYLIQRRY 895

Query: 1035 TYATIDGSVNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPS 1093
             Y  IDG V    R   ++ F+     + V L+   AGG+G+NLT  +   + D  WNP 
Sbjct: 896  LYERIDGRVRGNLRQAAIDRFSKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQ 955

Query: 1094 LEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL---SGSGESVT 1149
             + QA  R +R+GQ K V ++R +   + E ++      K  L K VL   SG   ++T
Sbjct: 956  NDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQSMSGRDGNIT 1014


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
            sapiens]
          Length = 1710

 Score =  134 bits (338), Expect = 4e-31
 Identities = 142/579 (24%), Positives = 237/579 (40%), Gaps = 135/579 (23%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q   L WL      K    ILAD+MGLGKT+  I+                   L +L 
Sbjct: 484  YQLNGLNWLA-HSWCKGNSCILADEMGLGKTIQTISF------------------LNYLF 524

Query: 633  KDDSCDFTSHGT-LIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLST--- 688
             +       +G  L++ P S +  W+ E++   +     VYL    +R+       T   
Sbjct: 525  HEHQL----YGPFLLVVPLSTLTSWQREIQTWASQMNAVVYLGDINSRNMIRTHEWTHHQ 580

Query: 689  -----YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVK 743
                 ++I++TTY ++ K+      +A + G N              WA I +DEAH +K
Sbjct: 581  TKRLKFNILLTTYEILLKD------KAFLGGLN--------------WAFIGVDEAHRLK 620

Query: 744  NPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSK 803
            N        +   ++  R  +TGTP+QN+L +++SLL F+    F  +  +  +   G +
Sbjct: 621  NDDSLLYKTLIDFKSNHRLLITGTPLQNSLKELWSLLHFIMPEKFSSWEDFEEEHGKGRE 680

Query: 804  KGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSR 863
             G   L    +  LLRR K  ++ +      LP +  Q+  +++S  ++  Y     R+ 
Sbjct: 681  YGYASLHKELEPFLLRRVKKDVEKS------LPAKVEQILRMEMSALQKQYYKWILTRNY 734

Query: 864  SALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRL 923
             AL        S+G+ SG                                   L+ ++ L
Sbjct: 735  KALSK-----GSKGSTSG----------------------------------FLNIMMEL 755

Query: 924  RQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMEL 983
            ++CC H  L+K                                 P +    N  + K E 
Sbjct: 756  KKCCNHCYLIKP--------------------------------PDN----NEFYNKQEA 779

Query: 984  FEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSV 1043
             + +  S+    LL +L  I+      + +I SQ   ML ++A +LK     +  +DGS+
Sbjct: 780  LQHLIRSSGKLILLDKL-LIRLRERGNRVLIFSQMVRMLDILAEYLKYRQFPFQRLDGSI 838

Query: 1044 NPKQRMDLVEAFNHSRGPQV-MLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRI 1102
              + R   ++ FN         L+S  AGG+G+NL   + + + D  WNP  + QA  R 
Sbjct: 839  KGELRKQALDHFNAEGSEDFCFLLSTRAGGLGINLASADTVVIFDSDWNPQNDLQAQARA 898

Query: 1103 YRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
            +R+GQ+K V I+R V +G+VEE IL+  +KK  L   V+
Sbjct: 899  HRIGQKKQVNIYRLVTKGSVEEDILERAKKKMVLDHLVI 937


>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
            sapiens]
          Length = 1954

 Score =  132 bits (331), Expect = 2e-30
 Identities = 148/598 (24%), Positives = 246/598 (41%), Gaps = 122/598 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL +  +Q     ILAD+MGLGKT+  I  + +      KE   K   L    
Sbjct: 703  YQLEGLNWLRFSWAQGTDT-ILADEMGLGKTVQTIVFLYSLY----KEGHSKGPYL---- 753

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIV 692
                         +  P S I +W+ E E  + +    V  Y G +++SR+ +       
Sbjct: 754  -------------VSAPLSTIINWEREFE--MWAPDFYVVTYTG-DKESRSVIRENEFSF 797

Query: 693  ITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRI--------AWARIILDEAHNVKN 744
                    K++   K+E +I     +V  TS  L+ I         WA +++DEAH +KN
Sbjct: 798  EDNAIRSGKKVFRMKKEVQI---KFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKN 854

Query: 745  PRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKK 804
             + +    +   +   +  +TGTP+QNNL +++ LL FL    F+    +  +  + SK+
Sbjct: 855  NQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKE 914

Query: 805  GG-ERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSR 863
               ++L  L    +LRR K  +         +P +   +  ++LS+ ++  Y     R+ 
Sbjct: 915  DQIKKLHDLLGPHMLRRLKADVFKN------MPAKTELIVRVELSQMQKKYYKFILTRNF 968

Query: 864  SALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRL 923
             AL S     +  GNQ                                  V +L+ ++ L
Sbjct: 969  EALNS-----KGGGNQ----------------------------------VSLLNIMMDL 989

Query: 924  RQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMEL 983
            ++CC H  L   A                                 + V  NG++    L
Sbjct: 990  KKCCNHPYLFPVAA------------------------------VEAPVLPNGSYDGSSL 1019

Query: 984  FEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSV 1043
             +   +   +  +L +L          + +I SQ T ML ++   L+  G  Y  IDG +
Sbjct: 1020 VKSSGKLMLLQKMLKKLR-----DEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGI 1074

Query: 1044 NPKQRMDLVEAFNHSRGPQV-MLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRI 1102
                R + ++ FN     Q   L+S  AGG+G+NL   + + + D  WNP  + QA  R 
Sbjct: 1075 TGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRA 1134

Query: 1103 YRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQV----LSGSGESVTKLTLADL 1156
            +R+GQ K V+I+RFV   +VEE+I Q+ ++K  L   V    L     S+TK  L D+
Sbjct: 1135 HRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDI 1192


>gi|192807323 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform A [Homo sapiens]
          Length = 1679

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|192807320 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform F [Homo sapiens]
          Length = 1613

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|192807318 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform E [Homo sapiens]
          Length = 1614

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|192807316 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform D [Homo sapiens]
          Length = 1616

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|192807314 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform C [Homo sapiens]
          Length = 1617

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|192807312 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|21071056 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a4 isoform B [Homo sapiens]
          Length = 1647

 Score =  131 bits (330), Expect = 3e-30
 Identities = 143/580 (24%), Positives = 243/580 (41%), Gaps = 118/580 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q + L WL+   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 757  YQIKGLEWLVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 801

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARV----LST 688
                    +   LII P S + +W  E +K   S  +    Y G     RA V       
Sbjct: 802  -------INGPFLIIVPLSTLSNWAYEFDKWAPS--VVKVSYKGSPAARRAFVPQLRSGK 852

Query: 689  YDIVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ 748
            +++++TTY  + K+                       L +I W  +I+DE H +KN   +
Sbjct: 853  FNVLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCK 892

Query: 749  -TSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGE 807
             T +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GE
Sbjct: 893  LTQVLNTHYVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGE 952

Query: 808  RLSILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--R 863
            ++ +  +   L++RR    L            R F L  LK   + +    V +      
Sbjct: 953  KVDLNEEETILIIRRLHKVL------------RPFLLRRLKKEVEAQLPEKVEYVIKCDM 1000

Query: 864  SALQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLR 922
            SALQ  L RH +++G             V L  GSE+ +        +  T  +++ +++
Sbjct: 1001 SALQRVLYRHMQAKG-------------VLLTDGSEKDKKG------KGGTKTLMNTIMQ 1041

Query: 923  LRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKME 982
            LR+ C H  + +   +           S  E L                    G    ++
Sbjct: 1042 LRKICNHPYMFQHIEE-----------SFSEHLGFT----------------GGIVQGLD 1074

Query: 983  LFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGS 1042
            L+    +   +  +L +L A      + K ++  Q T+++ ++  +    G  Y  +DG+
Sbjct: 1075 LYRASGKFELLDRILPKLRA-----TNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGT 1129

Query: 1043 VNPKQRMDLVEAFNHSRGPQ-VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDR 1101
               + R  L++ FN       + L+S  AGG+GLNL   + + + D  WNP  + QA DR
Sbjct: 1130 TKAEDRGMLLKTFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDR 1189

Query: 1102 IYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
             +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1190 AHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1229


>gi|48255900 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform a [Homo sapiens]
          Length = 1590

 Score =  130 bits (328), Expect = 6e-30
 Identities = 142/579 (24%), Positives = 240/579 (41%), Gaps = 116/579 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q Q L W++   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 727  YQLQGLEWMVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 771

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLST--YD 690
                    +   LII P S + +W  E +K   S     Y      R S    L +  ++
Sbjct: 772  -------LNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFN 824

Query: 691  IVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ-T 749
            +++TTY  + K+                       L +I W  +I+DE H +KN   + T
Sbjct: 825  VLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCKLT 864

Query: 750  SIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERL 809
             +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GER+
Sbjct: 865  QVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERV 924

Query: 810  SILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--RSA 865
             +  +   L++RR    L            R F L  LK   + +    V +      SA
Sbjct: 925  DLNEEETILIIRRLHKVL------------RPFLLRRLKKEVESQLPEKVEYVIKCDMSA 972

Query: 866  LQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLR 924
            LQ  L RH +++G             + L  GSE+ +  +       +T+      ++LR
Sbjct: 973  LQKILYRHMQAKG-------------ILLTDGSEKDKKGKGGAKTLMNTI------MQLR 1013

Query: 925  QCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELF 984
            + C H  + +                            + +S        NG     EL+
Sbjct: 1014 KICNHPYMFQ---------------------------HIEESFAEHLGYSNGVINGAELY 1046

Query: 985  EGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVN 1044
                +   +  +L +L A      + + ++  Q T+++ ++  +       Y  +DG+  
Sbjct: 1047 RASGKFELLDRILPKLRA-----TNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTK 1101

Query: 1045 PKQRMDLVEAFNHSRGPQ--VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRI 1102
             + R  L++ FN   G Q  + L+S  AGG+GLNL   + + + D  WNP  + QA DR 
Sbjct: 1102 SEDRAALLKKFNEP-GSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA 1160

Query: 1103 YRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
            +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1161 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1199


>gi|48255898 SWI/SNF-related matrix-associated actin-dependent
            regulator of chromatin a2 isoform b [Homo sapiens]
          Length = 1572

 Score =  130 bits (328), Expect = 6e-30
 Identities = 142/579 (24%), Positives = 240/579 (41%), Gaps = 116/579 (20%)

Query: 573  HQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLS 632
            +Q Q L W++   +     GILAD+MGLGKT+  IALI T   + K+             
Sbjct: 727  YQLQGLEWMVSLYNNN-LNGILADEMGLGKTIQTIALI-TYLMEHKR------------- 771

Query: 633  KDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLST--YD 690
                    +   LII P S + +W  E +K   S     Y      R S    L +  ++
Sbjct: 772  -------LNGPYLIIVPLSTLSNWTYEFDKWAPSVVKISYKGTPAMRRSLVPQLRSGKFN 824

Query: 691  IVITTYSLVAKEIPTNKQEAEIPGANLNVEGTSTPLLRIAWARIILDEAHNVKNPRVQ-T 749
            +++TTY  + K+                       L +I W  +I+DE H +KN   + T
Sbjct: 825  VLLTTYEYIIKD--------------------KHILAKIRWKYMIVDEGHRMKNHHCKLT 864

Query: 750  SIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERL 809
             +      A  R  +TGTP+QN L ++++LL FL  + F   + +    +      GER+
Sbjct: 865  QVLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGERV 924

Query: 810  SILTKS--LLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARS--RSA 865
             +  +   L++RR    L            R F L  LK   + +    V +      SA
Sbjct: 925  DLNEEETILIIRRLHKVL------------RPFLLRRLKKEVESQLPEKVEYVIKCDMSA 972

Query: 866  LQSYLKRH-ESRGNQSGRSPNNPFSRVALEFGSEEPRHSEAADSPRSSTVHILSQLLRLR 924
            LQ  L RH +++G             + L  GSE+ +  +       +T+      ++LR
Sbjct: 973  LQKILYRHMQAKG-------------ILLTDGSEKDKKGKGGAKTLMNTI------MQLR 1013

Query: 925  QCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELF 984
            + C H  + +                            + +S        NG     EL+
Sbjct: 1014 KICNHPYMFQ---------------------------HIEESFAEHLGYSNGVINGAELY 1046

Query: 985  EGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVN 1044
                +   +  +L +L A      + + ++  Q T+++ ++  +       Y  +DG+  
Sbjct: 1047 RASGKFELLDRILPKLRA-----TNHRVLLFCQMTSLMTIMEDYFAFRNFLYLRLDGTTK 1101

Query: 1045 PKQRMDLVEAFNHSRGPQ--VMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRI 1102
             + R  L++ FN   G Q  + L+S  AGG+GLNL   + + + D  WNP  + QA DR 
Sbjct: 1102 SEDRAALLKKFNEP-GSQYFIFLLSTRAGGLGLNLQAADTVVIFDSDWNPHQDLQAQDRA 1160

Query: 1103 YRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVL 1141
            +R+GQQ +V + R     +VEEKIL   + K ++ ++V+
Sbjct: 1161 HRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVI 1199


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,814,005
Number of Sequences: 37866
Number of extensions: 2379683
Number of successful extensions: 11406
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 417
Number of HSP's that attempted gapping in prelim test: 9600
Number of HSP's gapped (non-prelim): 1671
length of query: 1162
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1049
effective length of database: 13,968,660
effective search space: 14653124340
effective search space used: 14653124340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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