Search of human proteins with 40807368

Search of human proteins with 40807368

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40807368 potassium channel regulator isoform 2 [Homo
sapiens]
         (229 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]      463   e-131
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]      392   e-109
gi|189571693 potassium channel tetramerisation domain containing...    91   1e-18
gi|189571691 potassium channel tetramerisation domain containing...    91   1e-18
gi|71143104 potassium channel tetramerisation domain containing ...    84   1e-16
gi|55926200 potassium channel tetramerisation domain containing ...    82   4e-16
gi|218505694 potassium channel tetramerisation domain containing...    76   2e-14
gi|209969708 potassium channel tetramerisation domain containing...    76   2e-14
gi|40217617 potassium channel tetramerisation domain containing ...    76   2e-14
gi|194018443 potassium channel tetramerisation domain containing...    76   3e-14
gi|194018441 potassium channel tetramerisation domain containing...    76   3e-14
gi|194018439 potassium channel tetramerisation domain containing...    76   3e-14
gi|38198663 potassium channel tetramerisation domain containing ...    76   3e-14
gi|19923973 potassium channel tetramerisation domain containing ...    75   5e-14
gi|142356950 potassium channel tetramerisation domain containing...    67   2e-11
gi|146198864 potassium channel tetramerisation domain containing...    66   2e-11
gi|46255026 potassium channel tetramerisation domain containing ...    58   8e-09
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  57   1e-08
gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo sapi...    56   2e-08
gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo sapi...    56   2e-08
gi|23308551 potassium channel tetramerisation domain containing ...    56   3e-08
gi|148839316 NIMA-related kinase 4 [Homo sapiens]                      55   4e-08
gi|45387953 potassium channel tetramerization domain containing ...    55   5e-08
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]     52   6e-07
gi|6005810 mitogen-activated protein kinase kinase kinase kinase...    51   7e-07
gi|51036594 potassium channel tetramerisation domain containing ...    50   1e-06
gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform...    50   2e-06
gi|53829365 potassium channel tetramerisation domain containing ...    50   2e-06
gi|30578412 potassium channel tetramerisation domain containing ...    48   6e-06
gi|39753959 potassium channel tetramerisation domain containing ...    48   8e-06

>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score =  463 bits (1192), Expect = e-131
 Identities = 229/229 (100%), Positives = 229/229 (100%)

Query: 1   MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF 60
           MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
Sbjct: 1   MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ 120
           ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ 120

Query: 121 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC 180
           AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
Sbjct: 121 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC 180

Query: 181 GSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGMFL 229
           GSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGMFL
Sbjct: 181 GSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGMFL 229


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score =  392 bits (1008), Expect = e-109
 Identities = 194/195 (99%), Positives = 194/195 (99%)

Query: 1   MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF 60
           MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF
Sbjct: 1   MSSQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSF 60

Query: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ 120
           ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ
Sbjct: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPALVEVHFLSRNTQ 120

Query: 121 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC 180
           AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC
Sbjct: 121 AFFRVFGSCSKTIEMLTGRITVFTEQPSAPTWNGNFFPPQMTLLPLPPQRPSYHDLVFQC 180

Query: 181 GSDSTTDNQTGVRLV 195
           GSDSTTDNQTGVR V
Sbjct: 181 GSDSTTDNQTGVRYV 195


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 54/152 (35%), Positives = 82/152 (53%), Gaps = 6/152 (3%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66
           VTLNVGG ++TT  +T+ ++P S L  M  G     +   G  F+DRDG LF ++L+FLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEVHFLSRNTQAFFRV 125
           T +L LP +F ++  L++EA FY++  L+  LN P  L P     EV  LS       R 
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSST-----RK 128

Query: 126 FGSCSKTIEMLTGRITVFTEQPSAPTWNGNFF 157
               S  + ++  ++T+ T+  S      N+F
Sbjct: 129 LSKYSNPVAVIITQLTITTKVHSLLEGISNYF 160


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 90.5 bits (223), Expect = 1e-18
 Identities = 54/152 (35%), Positives = 82/152 (53%), Gaps = 6/152 (3%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66
           VTLNVGG ++TT  +T+ ++P S L  M  G     +   G  F+DRDG LF ++L+FLR
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTARDPQGNYFIDRDGPLFRYVLNFLR 73

Query: 67  THQLLLPTEFSDYLRLQREALFYELRSLVDLLN-PYLLQPRPALVEVHFLSRNTQAFFRV 125
           T +L LP +F ++  L++EA FY++  L+  LN P  L P     EV  LS       R 
Sbjct: 74  TSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMDTFEEVVELSST-----RK 128

Query: 126 FGSCSKTIEMLTGRITVFTEQPSAPTWNGNFF 157
               S  + ++  ++T+ T+  S      N+F
Sbjct: 129 LSKYSNPVAVIITQLTITTKVHSLLEGISNYF 160


>gi|71143104 potassium channel tetramerisation domain containing
          21 [Homo sapiens]
          Length = 260

 Score = 84.0 bits (206), Expect = 1e-16
 Identities = 41/92 (44%), Positives = 60/92 (65%)

Query: 7  VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFLR 66
          +TLNVGGK++TT  +T+  FP S L  M  G+    +   G  F+DRDG +F +IL+FLR
Sbjct: 5  ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTKRDSQGNCFIDRDGKVFRYILNFLR 64

Query: 67 THQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
          T  L LP +F +   L+REA FY+++ L++ L
Sbjct: 65 TSHLDLPEDFQEMGLLRREADFYQVQPLIEAL 96


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 82.0 bits (201), Expect = 4e-16
 Identities = 47/110 (42%), Positives = 67/110 (60%), Gaps = 4/110 (3%)

Query: 2   SSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----DGRDQEFKMVGGQIFVDRDGDL 57
           S  E+V LNVGG+++ TR ST+   P S L +M     D  +   K   G+ F+DRDG L
Sbjct: 22  SFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFL 81

Query: 58  FSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107
           F +ILD+LR  Q++LP  F +  RL+REA +++L  LV LL P  ++  P
Sbjct: 82  FRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSP 131


>gi|218505694 potassium channel tetramerisation domain containing 1
           isoform b [Homo sapiens]
          Length = 865

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR+ R+ DG +      +    F+DRDG +F +IL+FL
Sbjct: 640 VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 699

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LL+P +F DY  L  EA +++L+ ++
Sbjct: 700 RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 729


>gi|209969708 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR+ R+ DG +      +    F+DRDG +F +IL+FL
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LL+P +F DY  L  EA +++L+ ++
Sbjct: 92  RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|40217617 potassium channel tetramerisation domain containing 1
           isoform a [Homo sapiens]
          Length = 257

 Score = 76.3 bits (186), Expect = 2e-14
 Identities = 34/90 (37%), Positives = 60/90 (66%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR+ R+ DG +      +    F+DRDG +F +IL+FL
Sbjct: 32  VHIDVGGHMYTSSLATLTKYPESRIGRLFDGTEPIVLDSLKQHYFIDRDGQMFRYILNFL 91

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LL+P +F DY  L  EA +++L+ ++
Sbjct: 92  RTSKLLIPDDFKDYTLLYEEAKYFQLQPML 121


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 34/90 (37%), Positives = 61/90 (67%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR++R+ +G +      +    F+DRDG++F ++L FL
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LLLP +F D+  L  EA +Y+L+ +V
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMV 147


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 34/90 (37%), Positives = 61/90 (67%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR++R+ +G +      +    F+DRDG++F ++L FL
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LLLP +F D+  L  EA +Y+L+ +V
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMV 147


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 34/90 (37%), Positives = 61/90 (67%), Gaps = 1/90 (1%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQ-EFKMVGGQIFVDRDGDLFSFILDFL 65
           V ++VGG ++T+  +T+ ++P SR++R+ +G +      +    F+DRDG++F ++L FL
Sbjct: 58  VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQHYFIDRDGEIFRYVLSFL 117

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           RT +LLLP +F D+  L  EA +Y+L+ +V
Sbjct: 118 RTSKLLLPDDFKDFSLLYEEARYYQLQPMV 147


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 75.9 bits (185), Expect = 3e-14
 Identities = 43/105 (40%), Positives = 61/105 (58%), Gaps = 9/105 (8%)

Query: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDG---------RDQEFKMVGGQIFVDRDG 55
           E+V LNVGG+++ T+ ST+   P S LA M            R +  +    + F+DRDG
Sbjct: 44  EVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDG 103

Query: 56  DLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNP 100
            LF ++LD+LR  QL LP  F +  RL REA +++L  LV LL+P
Sbjct: 104 FLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSP 148


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 75.1 bits (183), Expect = 5e-14
 Identities = 42/93 (45%), Positives = 59/93 (63%), Gaps = 2/93 (2%)

Query: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQE--FKMVGGQIFVDRDGDLFSFIL 62
           ++V LNVGG+++ TR  T+   P S L RM   +  +   +   G+ F+DRDG LF +IL
Sbjct: 34  DIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQPQELARDSKGRFFLDRDGFLFRYIL 93

Query: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           D+LR  QL+LP  F +  RLQREA ++EL  LV
Sbjct: 94  DYLRDLQLVLPDYFPERSRLQREAEYFELPELV 126


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 66.6 bits (161), Expect = 2e-11
 Identities = 39/93 (41%), Positives = 54/93 (58%), Gaps = 4/93 (4%)

Query: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65
           +V LNVGG+  TT   T+++FP S+LA M     +      G+ F+DR    F  ILD+L
Sbjct: 34  VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYL 93

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
           RT Q  +PT+      + REA FYE++ LV LL
Sbjct: 94  RTGQ--VPTQHIP--EVYREAQFYEIKPLVKLL 122


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 66.2 bits (160), Expect = 2e-11
 Identities = 35/91 (38%), Positives = 57/91 (62%)

Query: 6   LVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDFL 65
           L+TLNVGG ++ T+  T+ ++P + L  +++G+        G  F+DRDG LF  +L+FL
Sbjct: 34  LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFDADGHYFIDRDGLLFRHVLNFL 93

Query: 66  RTHQLLLPTEFSDYLRLQREALFYELRSLVD 96
           R  +LLLP  F +   L +EA F++L+ L +
Sbjct: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 57.8 bits (138), Expect = 8e-09
 Identities = 39/93 (41%), Positives = 51/93 (54%), Gaps = 2/93 (2%)

Query: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62
           S E+V LNVGG  F+T   T+   P S  + +L GR    +   G IF+DRD   F+ IL
Sbjct: 16  SGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRISTLRDETGAIFIDRDPAAFAPIL 75

Query: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           +FLRT +L L     + LR   EA FY +  LV
Sbjct: 76  NFLRTKELDLRGVSINVLR--HEAEFYGITPLV 106


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 57.4 bits (137), Expect = 1e-08
 Identities = 38/91 (41%), Positives = 49/91 (53%), Gaps = 2/91 (2%)

Query: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64
           E++ LNVGGK F+T   T+   P S  + +L GR    K   G IF+DRD  +F+ IL+F
Sbjct: 19  EVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNF 78

Query: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLV 95
           LRT +  L         L  EA FY L  LV
Sbjct: 79  LRTKE--LDPRGVHGSSLLHEAQFYGLTPLV 107


>gi|219881538 hypothetical protein LOC199870 isoform 2 [Homo
           sapiens]
          Length = 312

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 28/35 (80%), Positives = 30/35 (85%)

Query: 193 RLVCNGVISAHHNLRLWGSSDSPASASRVAGITGM 227
           RL CNG ISAH NL L GSSDSPAS+SRVAGITG+
Sbjct: 49  RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGI 83


>gi|219881536 hypothetical protein LOC199870 isoform 1 [Homo
           sapiens]
          Length = 341

 Score = 56.2 bits (134), Expect = 2e-08
 Identities = 28/35 (80%), Positives = 30/35 (85%)

Query: 193 RLVCNGVISAHHNLRLWGSSDSPASASRVAGITGM 227
           RL CNG ISAH NL L GSSDSPAS+SRVAGITG+
Sbjct: 49  RLECNGTISAHCNLHLPGSSDSPASSSRVAGITGI 83


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 36/94 (38%), Positives = 53/94 (56%), Gaps = 3/94 (3%)

Query: 5   ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64
           E+V LN+GG  FTTR ST++ +  + LA M  GR        G+ F+DRDG  F  +L+F
Sbjct: 51  EVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGRHYIPTDSEGRYFIDRDGTHFGDVLNF 110

Query: 65  LRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
           LR+   L P E      + +EA +Y +  L++ L
Sbjct: 111 LRSGD-LPPRE--RVRAVYKEAQYYAIGPLLEQL 141


>gi|148839316 NIMA-related kinase 4 [Homo sapiens]
          Length = 841

 Score = 55.5 bits (132), Expect = 4e-08
 Identities = 27/35 (77%), Positives = 30/35 (85%)

Query: 193 RLVCNGVISAHHNLRLWGSSDSPASASRVAGITGM 227
           +L C+G I AH NLRL GSSDSPASASRVAGITG+
Sbjct: 463 KLECSGTILAHSNLRLLGSSDSPASASRVAGITGV 497


>gi|45387953 potassium channel tetramerization domain containing
          18 [Homo sapiens]
          Length = 426

 Score = 55.1 bits (131), Expect = 5e-08
 Identities = 31/85 (36%), Positives = 49/85 (57%), Gaps = 1/85 (1%)

Query: 5  ELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFILDF 64
          +++ LNVGG I+T R  ++ +F  S LA M  GR        G   +DRDG LF ++LD+
Sbjct: 12 DVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFPLKTDESGACVIDRDGRLFKYLLDY 71

Query: 65 LRTHQLLLPTEFSDYLRLQREALFY 89
          L   ++ +PT+    + LQ EA ++
Sbjct: 72 LH-GEVQIPTDEQTRIALQEEADYF 95


>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
          Length = 475

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 26/42 (61%), Positives = 32/42 (76%)

Query: 186 TDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGITGM 227
           T +++  RL C+G+I AH NLRL GS DSPASAS+ AG TGM
Sbjct: 424 TKSRSVTRLECSGMILAHCNLRLPGSRDSPASASQAAGTTGM 465


>gi|6005810 mitogen-activated protein kinase kinase kinase kinase 1
           isoform 2 [Homo sapiens]
          Length = 833

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 26/35 (74%), Positives = 29/35 (82%)

Query: 193 RLVCNGVISAHHNLRLWGSSDSPASASRVAGITGM 227
           RL C+G IS H NL L GSS+SPASASRVAGITG+
Sbjct: 799 RLECSGTISPHCNLLLPGSSNSPASASRVAGITGL 833


>gi|51036594 potassium channel tetramerisation domain containing
          11 [Homo sapiens]
          Length = 232

 Score = 50.4 bits (119), Expect = 1e-06
 Identities = 25/53 (47%), Positives = 34/53 (64%)

Query: 46 GGQIFVDRDGDLFSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
          GG  F+DRDG  F  IL+FLR  +L LP  + +   L+ EA FY++R L+D L
Sbjct: 21 GGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAEADFYQIRPLLDAL 73


>gi|189083762 gamma-aminobutyric acid A receptor, gamma 2 isoform 3
           precursor [Homo sapiens]
          Length = 515

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 26/52 (50%), Positives = 34/52 (65%), Gaps = 3/52 (5%)

Query: 174 HDLVFQCGSDSTTDNQTGVRLVCNGVISAHHNLRLWGSSDSPASASRVAGIT 225
           H    +  S S +  Q G+   C+GVISAH++LR WGS+D P  ASRVAGI+
Sbjct: 202 HSCPLEFSSWSRSIAQAGM---CSGVISAHYSLRFWGSTDPPTLASRVAGIS 250


>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEF---KMVGGQIFVDRDGDLFSFILD 63
           V LNVGG  F T   T+ + P S L R+    D E    K   G   +DRD   F  IL+
Sbjct: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133

Query: 64  FLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98
           +LR  +L++  E ++   L+ EA FY + SLV L+
Sbjct: 134 YLRHGKLIITKELAEEGVLE-EAEFYNIASLVRLV 167


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 48.1 bits (113), Expect = 6e-06
 Identities = 33/107 (30%), Positives = 50/107 (46%), Gaps = 1/107 (0%)

Query: 3   SQELVTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEFKMVGGQIFVDRDGDLFSFIL 62
           + + V LNVGG +  T   T+     + L  M  GR +     GG + +DR G  F  IL
Sbjct: 39  NSKYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTIL 97

Query: 63  DFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRPAL 109
           ++LR   + LP    +   L  EA +Y ++ L++     L Q R  L
Sbjct: 98  NYLRDGSVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETL 144


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 36/107 (33%), Positives = 56/107 (52%), Gaps = 10/107 (9%)

Query: 7   VTLNVGGKIFTTRFST-IKQFPASRLARMLD-----GRDQEFKMVGGQIFVDRDGDLFSF 60
           +TLNVGG+ FTT  ST + + P S LA M       G  Q+ +   G   +DR  + F  
Sbjct: 91  LTLNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNKQDHR---GAFLIDRSPEYFEP 147

Query: 61  ILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107
           IL++LR H  L+  +  + L +  EA F+ + SL++ L   +   +P
Sbjct: 148 ILNYLR-HGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQP 193


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.325    0.139    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,619,399
Number of Sequences: 37866
Number of extensions: 379228
Number of successful extensions: 1391
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 81
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 1273
Number of HSP's gapped (non-prelim): 116
length of query: 229
length of database: 18,247,518
effective HSP length: 99
effective length of query: 130
effective length of database: 14,498,784
effective search space: 1884841920
effective search space used: 1884841920
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.