BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase 4 [Homo sapiens] (1039 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transfera... 2137 0.0 gi|71043500 beta 1,4-N-acetylgalactosaminyltransferase-transfera... 873 0.0 gi|194473684 chondroitin sulfate N-acetylgalactosaminyltransfera... 85 3e-16 gi|194473683 chondroitin sulfate N-acetylgalactosaminyltransfera... 85 3e-16 gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 78 5e-14 gi|24429592 chondroitin sulfate N-acetylgalactosaminyltransferas... 76 1e-13 gi|31542309 chondroitin sulfate synthase 1 [Homo sapiens] 73 1e-12 gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 69 2e-11 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 2e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 63 2e-09 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 63 2e-09 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 63 2e-09 gi|19924099 synapsin I isoform Ia [Homo sapiens] 62 3e-09 gi|19924097 synapsin I isoform Ib [Homo sapiens] 62 3e-09 gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens] 61 5e-09 gi|11386183 WAS protein family, member 2 [Homo sapiens] 61 6e-09 gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 60 1e-08 gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 59 2e-08 gi|163965366 nascent polypeptide-associated complex alpha subuni... 59 2e-08 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 2e-08 gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 59 2e-08 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 59 3e-08 gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Ho... 59 3e-08 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 58 5e-08 gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 57 7e-08 gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 57 7e-08 gi|117306167 proline-rich protein BstNI subfamily 3 precursor [H... 57 7e-08 gi|110832843 TBP-associated factor 4 [Homo sapiens] 57 9e-08 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 57 9e-08 gi|210032580 SET domain containing 1B [Homo sapiens] 57 9e-08 >gi|40789265 beta 1,4-N-acetylgalactosaminyltransferase-transferase 4 [Homo sapiens] Length = 1039 Score = 2137 bits (5537), Expect = 0.0 Identities = 1039/1039 (100%), Positives = 1039/1039 (100%) Query: 1 MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGEKLTSETD 60 MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGEKLTSETD Sbjct: 1 MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGEKLTSETD 60 Query: 61 GRGVHAAPSTQRAEDSSESREEEQAPEGRDLDMLFPGGAGRLPLNFTHQTPPWREEYKGQ 120 GRGVHAAPSTQRAEDSSESREEEQAPEGRDLDMLFPGGAGRLPLNFTHQTPPWREEYKGQ Sbjct: 61 GRGVHAAPSTQRAEDSSESREEEQAPEGRDLDMLFPGGAGRLPLNFTHQTPPWREEYKGQ 120 Query: 121 VNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGD 180 VNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGD Sbjct: 121 VNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGD 180 Query: 181 VQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASR 240 VQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASR Sbjct: 181 VQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASR 240 Query: 241 RYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSP 300 RYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSP Sbjct: 241 RYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSP 300 Query: 301 ASHVGGRPPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARY 360 ASHVGGRPPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARY Sbjct: 301 ASHVGGRPPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARY 360 Query: 361 QGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDE 420 QGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDE Sbjct: 361 QGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDE 420 Query: 421 VQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPP 480 VQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPP Sbjct: 421 VQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPP 480 Query: 481 RPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRA 540 RPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRA Sbjct: 481 RPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRA 540 Query: 541 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGR 600 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGR Sbjct: 541 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGR 600 Query: 601 EGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAA 660 EGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAA Sbjct: 601 EGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAA 660 Query: 661 SEDSEEAAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVD 720 SEDSEEAAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVD Sbjct: 661 SEDSEEAAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVD 720 Query: 721 VTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLR 780 VTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLR Sbjct: 721 VTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLR 780 Query: 781 LPGARVGDADGESPEPAPAASVRPDGRPELCRPLRLAWRQDVMVHFIVPVKNQARWVAQF 840 LPGARVGDADGESPEPAPAASVRPDGRPELCRPLRLAWRQDVMVHFIVPVKNQARWVAQF Sbjct: 781 LPGARVGDADGESPEPAPAASVRPDGRPELCRPLRLAWRQDVMVHFIVPVKNQARWVAQF 840 Query: 841 LADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAG 900 LADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAG Sbjct: 841 LADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAG 900 Query: 901 VDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWE 960 VDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWE Sbjct: 901 VDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWE 960 Query: 961 VNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYH 1020 VNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYH Sbjct: 961 VNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYH 1020 Query: 1021 SKRGMWSVRSRKGSRTGAS 1039 SKRGMWSVRSRKGSRTGAS Sbjct: 1021 SKRGMWSVRSRKGSRTGAS 1039 >gi|71043500 beta 1,4-N-acetylgalactosaminyltransferase-transferase 3 [Homo sapiens] Length = 998 Score = 873 bits (2256), Expect = 0.0 Identities = 497/1053 (47%), Positives = 638/1053 (60%), Gaps = 96/1053 (9%) Query: 5 PVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQ--GRALRQRLGYGRDGEKLTSETDGR 62 PVK +R++ +LLL L ++S W Y+ L Q G L +R G R+ L R Sbjct: 15 PVKLLRRRFRLLLALAVVSVGLWTLYLELVASAQVGGNPLNRRYGSWRE---LAKALASR 71 Query: 63 GVHAA-PSTQRAEDSSESREEEQAPEGRDLDMLFPGGAGRLPLNFTHQTPPWREEYKGQV 121 + A P Q S E+ D+D + L N + PW E++G+ Sbjct: 72 NIPAVDPHLQFYHPQRLSLEDH------DIDQGVSSNSSYLKWN---KPVPWLSEFRGRA 122 Query: 122 NLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGDV 181 NLHVFEDWCG ++ LRRNLHFPL+PH RTT++KLAVSPKW NYGLRIFG++HP DG + Sbjct: 123 NLHVFEDWCGSSIQQLRRNLHFPLYPHIRTTLRKLAVSPKWTNYGLRIFGYLHPFTDGKI 182 Query: 182 QFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRR 241 QF++A+DDN+EFWLSLD+ + QL+A VGKTG EWTAPGEF KF SQ+SKP L AS R Sbjct: 183 QFAIAADDNAEFWLSLDDQVSGLQLLASVGKTGKEWTAPGEFGKFRSQISKPVSLSASHR 242 Query: 242 YYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSPA 301 YYFE+LHKQ++ G+DHVEV WR PG KF +I S +SL+T+E+ L+MD V H+PQ+ A Sbjct: 243 YYFEVLHKQNEEGTDHVEVAWRRNDPGAKFTIIDSLSLSLFTNETFLQMDEVGHIPQTAA 302 Query: 302 SHVGGR---PPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIA 358 SHV P E+ ADMLRPDPRDT + P + S L +VL C Y P+Y+V P+ Sbjct: 303 SHVDSSNALPRDEQPPADMLRPDPRDTLYRVPLIPKSHLRHVLPDCPYKPSYLVDGLPLQ 362 Query: 359 RYQGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEE 418 RYQGL+FV+LSFVYPNDYTRL+HMET NKCFY+E+ Y +RF F +Y+K+D+ E E+ Sbjct: 363 RYQGLRFVHLSFVYPNDYTRLSHMETHNKCFYQENAYYQDRFSFQEYIKIDQPEKQGLEQ 422 Query: 419 DEVQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGAT----- 473 + ++ L++ GE+ + + R PA+ + AT Sbjct: 423 PGFE---------ENLLEESQYGEVAEETPASNNQNARMLEGRQTPASTLEQDATDYRLR 473 Query: 474 LAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPG 533 +PR+G S+ S A+ F GR V+QP + P Sbjct: 474 SLRKLLAQPREGLLAPFSKRNSTAS--------FPGRTS--HIPVQQPEKRKQKPSPEPS 523 Query: 534 QRASPRAPAPRAPWPPFPGVFLHP-RPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPAR 592 Q SP + WPP HP + LP Q+R P PRP G P+ TQ Sbjct: 524 QD-SPHSDK----WPPG-----HPVKNLP--QMRGPR--PRPAG---DSPRKTQWLNQVE 566 Query: 593 AQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGEEEEEGEDD 652 + + R + R P AP E V + QV G + EGEEEEE ED Sbjct: 567 SYIAEQRRGDRMR---PQAP--GRGWHGEEEVVAAAGQEGQVEGEE---EGEEEEEEED- 617 Query: 653 GAPGDEAASEDSEEAAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQ 712 SE E P + ++W +TFS +DF+ LR+DW DL CN SGNL Sbjct: 618 -------MSEVFEYV--PVF----DPVVNWDQTFSARNLDFQALRTDWIDLSCNTSGNLL 664 Query: 713 LPEAEAVDVTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLR 772 LPE EA++VT ++++LN R GR+ L RIVNVEKR+D RG R+LLELEL E+G +R Sbjct: 665 LPEQEALEVTRVFLKKLNQRSRGRYQLQRIVNVEKRQDQLRGGRYLLELELLEQGQRVVR 724 Query: 773 LSEYVFLRLPGARVGDADGESPEPAPAASV--RPDGR-----------PELCRPLRLAWR 819 LSEYV R + A GE E + P R P+LC P +W Sbjct: 725 LSEYVSAR-GWQGIDPAGGEEVEARNLQGLVWDPHNRRRQVLNTRAQEPKLCWPQGFSWS 783 Query: 820 QDVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARL 879 +VHF+VPVKNQARWV QF+ DM L TGD F++V+ D+ SEDMDVE AL+ ++L Sbjct: 784 HRAVVHFVVPVKNQARWVQQFIKDMENLFQVTGDPHFNIVITDYSSEDMDVEMALKRSKL 843 Query: 880 PRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAF 939 YQY++ +GNFERSAGLQAG+D V+D SI+FLCDLHIHFP ++D IRKHCVEG++AF Sbjct: 844 RSYQYVKLSGNFERSAGLQAGIDLVKDPHSIIFLCDLHIHFPAGVIDAIRKHCVEGKMAF 903 Query: 940 APVVMRLSCGSSPRDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDR 999 AP+VMRL CG++P+ P GYWEVNGFGL GIYKSD DR+GGMNT+EFRD+WGGEDWELLDR Sbjct: 904 APMVMRLHCGATPQWPEGYWEVNGFGLLGIYKSDLDRIGGMNTKEFRDRWGGEDWELLDR 963 Query: 1000 VLQAGLEVERLRLRNFYHHYHSKRGMWSVRSRK 1032 +LQAGL+VERL LRNF+HH+HSKRGMWS R K Sbjct: 964 ILQAGLDVERLSLRNFFHHFHSKRGMWSRRQMK 996 >gi|194473684 chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Homo sapiens] Length = 532 Score = 85.1 bits (209), Expect = 3e-16 Identities = 59/226 (26%), Positives = 102/226 (45%), Gaps = 24/226 (10%) Query: 821 DVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMD-----VERALR 875 + +++ IVP+ + QF+ + + D R + +V F E+++ +E + Sbjct: 260 NTLINVIVPLAKRVDKFRQFMQNFREMCIEQ-DGRVHLTVVYFGKEEINEVKGILENTSK 318 Query: 876 AARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEG 935 AA + +++ G F R GL G + ++ ++F CD+ I+F L+ R + G Sbjct: 319 AANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPG 378 Query: 936 RLAFAPVVMR-----LSCGSSPRDP-----------HGYWEVNGFGLFGIYKSDFDRVGG 979 + F PV+ + G P G+W GFG+ Y+SDF +GG Sbjct: 379 KKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRDFGFGMTCQYRSDFINIGG 438 Query: 980 MNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKRGM 1025 + + WGGED L + L + L V R +R +H +H KR M Sbjct: 439 FDLD--IKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKRCM 482 >gi|194473683 chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Homo sapiens] Length = 532 Score = 85.1 bits (209), Expect = 3e-16 Identities = 59/226 (26%), Positives = 102/226 (45%), Gaps = 24/226 (10%) Query: 821 DVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMD-----VERALR 875 + +++ IVP+ + QF+ + + D R + +V F E+++ +E + Sbjct: 260 NTLINVIVPLAKRVDKFRQFMQNFREMCIEQ-DGRVHLTVVYFGKEEINEVKGILENTSK 318 Query: 876 AARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEG 935 AA + +++ G F R GL G + ++ ++F CD+ I+F L+ R + G Sbjct: 319 AANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPG 378 Query: 936 RLAFAPVVMR-----LSCGSSPRDP-----------HGYWEVNGFGLFGIYKSDFDRVGG 979 + F PV+ + G P G+W GFG+ Y+SDF +GG Sbjct: 379 KKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRDFGFGMTCQYRSDFINIGG 438 Query: 980 MNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKRGM 1025 + + WGGED L + L + L V R +R +H +H KR M Sbjct: 439 FDLD--IKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKRCM 482 >gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] Length = 538 Score = 77.8 bits (190), Expect = 5e-14 Identities = 111/388 (28%), Positives = 140/388 (36%), Gaps = 64/388 (16%) Query: 450 TEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLG 509 T APPR+ +PA AA A P T APP PP P P +RA AA AA Sbjct: 107 TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP--ARAPRAAAAAA-------- 156 Query: 510 RAPPPRPAVEQPPPKVYVTRVRPGQRASPRA---PAPRAPWPPFPGVFLHPRPLPRVQLR 566 PP P QP P+ QRA+P A PAP AP P P P V R Sbjct: 157 -TAPPSPGPAQPGPR--------AQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAR 207 Query: 567 APPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVT 626 PP PP P + PQ QP PP +G G R G A P R V Sbjct: 208 EPPLPPPP--QPPAPPQQQQPPPPQPQPPPEG---GAVRAGGAARPV-------SLREVV 255 Query: 627 SFLSLSQVSGPQLPG---EGEEEEEGEDDG-----APGDEAASEDSEEAAGPALGRWRED 678 +L S +G +L +G EEE G G A P R Sbjct: 256 RYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPS 315 Query: 679 AIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVTAQYMERLNARHGGRFA 738 V + E + D +VS ++PE++ AQ+ +LN G + A Sbjct: 316 RSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDR-PAGAQH-HQLNGERGPQSA 373 Query: 739 LLRI-----VNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLRLPGARVGDADG-E 792 R+ + +D RG G G ++ + G A G + Sbjct: 374 KERVKEWTPCGPHQGQDEGRG---------PAPGSGTRQVFSMAAMNKEGGTASVATGPD 424 Query: 793 SPEPAPAASVRP-----DGRPELCRPLR 815 SP P P +P DG P C P R Sbjct: 425 SPSPVPLPPGKPALPGADGTPFGCPPGR 452 Score = 57.0 bits (136), Expect = 9e-08 Identities = 69/248 (27%), Positives = 88/248 (35%), Gaps = 58/248 (23%) Query: 449 PTEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLP 505 PT A PP P +PA A A A APP+P + G RA R P Sbjct: 129 PTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPG------------PRAQRAAP 176 Query: 506 LFLGRAPPPRPAVEQPP---PKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 L APPP PA PP P R P A+ P P P PP P P+ Sbjct: 177 L---AAPPPAPAA--PPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAP---------PQ 222 Query: 563 VQLRAPPRP-PRPHG---RRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNL 618 Q PP+P P P G R G + R R GG G+ T G ++ Sbjct: 223 QQQPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRL-TRGRVQGLLEEEA 281 Query: 619 SSEARPVTSFLSLSQVSGPQLPGEG---------------------EEEEEGEDDGAPGD 657 ++ R + L + PG +EEEE +D+ + Sbjct: 282 AARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEE 341 Query: 658 EAASEDSE 665 + SE SE Sbjct: 342 DDVSEGSE 349 >gi|24429592 chondroitin sulfate N-acetylgalactosaminyltransferase 2 [Homo sapiens] Length = 542 Score = 76.3 bits (186), Expect = 1e-13 Identities = 57/224 (25%), Positives = 91/224 (40%), Gaps = 28/224 (12%) Query: 823 MVHFIVPVKNQARWVAQFLADM--AALHARTGDSRFSVVLVDFESEDMD-----VERALR 875 +++ IVP+ + QF+ + +H D + + +V F E + +E Sbjct: 271 IINIIVPLAERTEAFVQFMQNFRDVCIHQ---DKKIHLTVVYFGKEGLSKVKSILESVTS 327 Query: 876 AARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEG 935 + Y + F R GL G A + ++F CD+ I+F L+ R + G Sbjct: 328 ESNFHNYTLVSLNEEFNRGRGLNVGARAWDKGEVLMFFCDVDIYFSAEFLNSCRLNAEPG 387 Query: 936 RLAFAPVVMRLSCGS----------------SPRDPHGYWEVNGFGLFGIYKSDFDRVGG 979 + F PVV L + + G+W GFG+ Y+SDF +GG Sbjct: 388 KKVFYPVVFSLYNPAIVYANQEVPPPVEQQLVHKKDSGFWRDFGFGMTCQYRSDFLTIGG 447 Query: 980 MNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKR 1023 + E WGGED L + L L V R + +H +H KR Sbjct: 448 FDMEV--KGWGGEDVHLYRKYLHGDLIVIRTPVPGLFHLWHEKR 489 >gi|31542309 chondroitin sulfate synthase 1 [Homo sapiens] Length = 802 Score = 73.2 bits (178), Expect = 1e-12 Identities = 56/221 (25%), Positives = 96/221 (43%), Gaps = 23/221 (10%) Query: 820 QDVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARL 879 +D ++ ++P+ + +F+ + + VVL+ + D + + R Sbjct: 530 KDKKINILIPLSGRFDMFVRFMGNFEKTCLIPNQNVKLVVLLFNSDSNPDKAKQVELMRD 589 Query: 880 PRYQY-------LRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHC 932 R +Y L +G F R+ L+ G + S++F CD+ + F L R + Sbjct: 590 YRIKYPKADMQILPVSGEFSRALALEVGSSQFNN-ESLLFFCDVDLVFTTEFLQRCRANT 648 Query: 933 VEGRLAFAPVVMR------LSCGSSPRDPH-------GYWEVNGFGLFGIYKSDFDRVGG 979 V G+ + P++ + G P D H G+W GFG+ IYK D RVGG Sbjct: 649 VLGQQIYFPIIFSQYDPKIVYSGKVPSDNHFAFTQKTGFWRNYGFGITCIYKGDLVRVGG 708 Query: 980 MNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYH 1020 + WG ED +L ++V+QAGL+ R + H +H Sbjct: 709 FDVS--IQGWGLEDVDLFNKVVQAGLKTFRSQEVGVVHVHH 747 >gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 isoform a [Homo sapiens] Length = 1006 Score = 68.9 bits (167), Expect = 2e-11 Identities = 69/229 (30%), Positives = 92/229 (40%), Gaps = 32/229 (13%) Query: 461 SPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQ 520 SP PA PA P T APP PPR S W + R+ PAV Sbjct: 770 SPPPAQPAAPSTTSAPPLPPRNVGKVQTASSANTLWKTNSVSVDGGSRQRSSSDPPAVHP 829 Query: 521 PPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHP-RPLPR--VQLRAPPRPPRPHGR 577 P P + VT P +P P P A P P +P P Q+R PP PP+P R Sbjct: 830 PLPPLRVTSTNP---LTPTPPPPVAKTPSVMEALSQPSKPAPPGISQIRPPPLPPQPPSR 886 Query: 578 ------RTGGPQAT------QPRPPARAQATQG-GREGQARTLGPAAPTVDSNLSSEARP 624 G ++T QPR P AT+ G A L P AP + +++ +P Sbjct: 887 LPQKKPAPGADKSTPLTNKGQPRGPVDLSATEALGPLSNAMVLQPPAPMPRKSQATKLKP 946 Query: 625 --VTSFLS--------LSQVSGPQLPGEGEEEEE---GEDDGAPGDEAA 660 V + + L+ G + +GEE++E G DG PG + A Sbjct: 947 KRVKALYNCVADNPDELTFSEGDVIIVDGEEDQEWWIGHIDGDPGRKGA 995 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 2e-09 Identities = 69/247 (27%), Positives = 91/247 (36%), Gaps = 39/247 (15%) Query: 431 PDDFLDDEDEG---------ELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPR 481 PDDF D E G L S+ + P + G P P PG PP Sbjct: 100 PDDFADKEVTGTSSLVNGNLRLYSSVG--DLRPGQYGQDLLIPPPP--PGPAPGPPQDIS 155 Query: 482 PRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAP 541 GG+P S + A P PL L PPP P++ PPP V P +SP P Sbjct: 156 EPPGGSPLPSPP----STAPPPPPLLL--EPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209 Query: 542 APRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPA-----RAQAT 596 P PP P + P P V APP P PH T+ PP ++ Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPH------TVGTRLFPPGGVTKWKSDVA 263 Query: 597 QGGREGQARTLGP---AAPTVDSNLSSEARPVTSFLSLSQVSGP------QLPGEGEEEE 647 GR+ +A P A S L P +F +V P +P + +E Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 648 EGEDDGA 654 +++GA Sbjct: 324 PRKEEGA 330 Score = 33.1 bits (74), Expect = 1.4 Identities = 48/207 (23%), Positives = 67/207 (32%), Gaps = 27/207 (13%) Query: 436 DDEDEGELLDSLEPTEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSR 492 D E + L+ T A PR G Q+ A P L PP PP P Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP----- 409 Query: 493 ALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPG 552 AA PLP A PP + P P + P P+P P Sbjct: 410 ----LPPAAPPLPCAQKAAHPPAGFTKTPKSS------SPALKPKPNPPSPENTASSAPV 459 Query: 553 VFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP 612 + P + + LR RR + +P P Q+ +G + GP P Sbjct: 460 DWRDPSQMEK--LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK-------GPRLP 510 Query: 613 TVDSNLSSEARPVTSFLSLSQVSGPQL 639 ++ LS A+ + + G L Sbjct: 511 EKETLLSLPAKDTPPGVPEKSLGGSSL 537 Score = 30.4 bits (67), Expect = 9.1 Identities = 57/218 (26%), Positives = 73/218 (33%), Gaps = 33/218 (15%) Query: 446 SLEPTEAAPPRSGPQS-PAPAAPAQPGATLAPPTPPRPRDG-GTPRHSRALSWAARAARP 503 SL+P P P++ P PA P P ATL P TPP+ G TP L + P Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIP--PKATLWPATPPKATLGPATP-----LKATSGPTTP 682 Query: 504 LPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRV 563 L G A + G P PA + P Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP-------------S 729 Query: 564 QLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEAR 623 Q R P T G +++ PP + + GG G+ L S+LS E Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPP---KTSPGG--GEVPCL-YKPHCHQSSLSREVA 783 Query: 624 PVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAAS 661 V L+ +GP GE E E G P AS Sbjct: 784 VVMPTLARGGAAGP-----GEPVEVKEPPGLPAKPPAS 816 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 62.8 bits (151), Expect = 2e-09 Identities = 74/256 (28%), Positives = 92/256 (35%), Gaps = 54/256 (21%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPP---------RPRDGGTPRHSRALSWAAR 499 P+ AAPP P SP + P P AT P PP P +P S + + R Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756 Query: 500 AARPL---PLFLGRAPP---PRPAVEQPPPKVYVTRVRPGQRASPRAPAP---RAPWPPF 550 L PL + +PP P + +PPP+ P +A P PA +AP+ P Sbjct: 757 VPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816 Query: 551 PGVFLHPRPLPRVQ---------LRAPPRPPRPHGRRTGGPQATQP-RPPARAQATQGGR 600 + + P P Q L+ PP PP P P RPP T Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPP-------ASPTLQAPRRPPTPGPDTSVSG 869 Query: 601 EGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGE------EEEEGEDDGA 654 L P P S S S +SGP L G EE G D G Sbjct: 870 PRLTLALAPGPPPPPSRSPS-----------STLSGPDLAGHSSSATSTPEELRGYDSGP 918 Query: 655 PGDEAAS--EDSEEAA 668 G AAS D+E AA Sbjct: 919 EGGAAASPPPDAELAA 934 Score = 55.1 bits (131), Expect = 3e-07 Identities = 62/220 (28%), Positives = 82/220 (37%), Gaps = 42/220 (19%) Query: 444 LDSLEPTEAAPPRS------GPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWA 497 L +L P + PPR GP S +P A P T A P PP P + TP + L + Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPP-PDNAATPLPA-TLPPS 334 Query: 498 ARAARPLPLF--LGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPP----FP 551 A PLPL APP + PP P +A P P PP P Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPP-------ATPPSQAPPSMTTPPMQAPPSLQTIP 387 Query: 552 GVFLHPRPLPRVQLRAPPRP-----------------PRPHGRRTGGPQATQ---PRPPA 591 + + P L L+APP P H T P+ TQ P Sbjct: 388 PIQV-PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446 Query: 592 RAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSL 631 A QA PA+P + ++LS P++S L++ Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI 486 Score = 45.8 bits (107), Expect = 2e-04 Identities = 47/156 (30%), Positives = 60/156 (38%), Gaps = 14/156 (8%) Query: 449 PTEAAPPRSG----PQSPAPAAPAQPGATLA-PPTPPRPRDGGTPRHSRALSWAARAARP 503 P A+PP G P SP P Q LA PP P +P S + + +A Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA 655 Query: 504 LPLFLGRAP---PPRPAVEQP-----PPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFL 555 L + L +AP PP P V+ P P V + P Q A P AP PP P Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPPASP 714 Query: 556 HPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPA 591 P +APP P + P A+ P P+ Sbjct: 715 PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750 Score = 45.1 bits (105), Expect = 4e-04 Identities = 56/191 (29%), Positives = 70/191 (36%), Gaps = 12/191 (6%) Query: 442 ELLDSLEPTE---AAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAA 498 E L SL P A+ P + P P PA P APP+P TP A Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPETPSSIATPPPQA 594 Query: 499 RAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPA--PRAPW-PPFPGVFL 555 A P G PP + PPP+ P +A P PA P +P P P Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA-- 652 Query: 556 HPRPLPRVQLRAP-PRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLG-PAAPT 613 P L L+AP PP P + P A+ P P+ +Q A L P +P Sbjct: 653 -PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711 Query: 614 VDSNLSSEARP 624 +S A P Sbjct: 712 ASPPMSPSATP 722 Score = 40.0 bits (92), Expect = 0.011 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 39/194 (20%) Query: 455 PRSGP--------QSPAPAAPAQPGATLAPP---TPPRP-----RDGGTPRHSRALSWAA 498 PR+GP ++PA PA APP T P P R GT R Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 499 RAARPLPLFLGRAP--PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFP----- 551 R + + G+A P R A+ G R P P P P Sbjct: 135 RISAEETVARGKATEAPKRSALSA------------GARRDTSGPTPGTPSPAMARRSRA 182 Query: 552 -GVFLH-PRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGP 609 G + PRP P + R P PR T+P P AR + + GG G R Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASR 240 Query: 610 AAPTVDSNLSSEAR 623 + + + LSS AR Sbjct: 241 SLSSSATPLSSPAR 254 Score = 39.7 bits (91), Expect = 0.015 Identities = 48/194 (24%), Positives = 64/194 (32%), Gaps = 20/194 (10%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPR----HSRALSWAARAARPL 504 P A P P SP P + +++A P P P +P S LS A Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA 621 Query: 505 PLFLGRAP---PPRPAVEQP----------PPKVYVTRVRPGQRASPRAPAPRAPWPPFP 551 P L P PP P P P + + P +P +AP+ P Sbjct: 622 PPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 681 Query: 552 GVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLG-PA 610 + P P Q APP P + P A+ P P+ Q A L P Sbjct: 682 SPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739 Query: 611 APTVDSNLSSEARP 624 +P +S A P Sbjct: 740 SPPASPPMSPSATP 753 Score = 39.7 bits (91), Expect = 0.015 Identities = 77/302 (25%), Positives = 98/302 (32%), Gaps = 81/302 (26%) Query: 444 LDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTP-----PRPRDGGTPRHSRALSWAA 498 L +L A+ P P SP+ + P P AT P P P + +P S L Sbjct: 797 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 856 Query: 499 RAARPLP--------LFLGRAPPPRPAVEQPPPKVYVTRVRPGQRAS------------- 537 R P P L L AP P P + P G +S Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916 Query: 538 -PRAPAPRAPWPPFPGVFLHPR-----PLPRVQLRAPPRPPRPHGRRTG----------- 580 P A +P P HP P P + R P P P TG Sbjct: 917 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 976 Query: 581 ---GPQATQPRP----PARAQATQGGREG-------------QAR----TLGPAAPTVDS 616 GP++ P P P + T GG+ QAR LG +V Sbjct: 977 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 1036 Query: 617 NLSSEARPVTSFLSLSQ-VSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRW 675 +L S T L+ ++ +G G G E G GA AA D+E LGRW Sbjct: 1037 HLLSR----TLLLAAAEGAAGGSGGGPGGAEGGGVTGGA---RAALSDAE------LGRW 1083 Query: 676 RE 677 E Sbjct: 1084 AE 1085 Score = 37.7 bits (86), Expect = 0.057 Identities = 60/234 (25%), Positives = 85/234 (36%), Gaps = 31/234 (13%) Query: 456 RSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLF-----LGR 510 ++G + PAA A T PP PRP TP R L AA A PL +G Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLG-AAGAVGRKPLAERAGGIGG 67 Query: 511 APPPRPAVEQPPPKVYVTRVR-PGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPP 569 A P A P + T R P R RAP P P P+ + Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPGPVSSPGRASGT 123 Query: 570 RPPRPHGRRTGGPQATQPRPPARAQATQGGRE------GQARTLGPAAPTVDSNLSSEAR 623 P P G++ G + + AR +AT+ + + T GP T ++ +R Sbjct: 124 TRPGPLGQK--GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 624 PVTSFLSL---SQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGR 674 + + L + + P+ P EG + +ASE S PA R Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSV---------SSASEHSTTEPSPAARR 226 Score = 37.4 bits (85), Expect = 0.074 Identities = 47/150 (31%), Positives = 54/150 (36%), Gaps = 47/150 (31%) Query: 452 AAPPRSGPQSP----APAAPAQPGA----TLAPP--TPPRPRDGGTPRHSRALSWAARAA 501 ++P RSGP + APA P+QP L PP TPPR AA A Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD-------------AAPAL 296 Query: 502 RPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLP 561 PL P P +P P P A+ PA P PP PLP Sbjct: 297 GPLSSSPLATPSPSGTKARPVP--------PPDNAATPLPATLPPSPPLA------TPLP 342 Query: 562 RVQLRAPPRPPRPHGRRTGGPQATQPRPPA 591 APP P P +T P PPA Sbjct: 343 L----APPSPSAPPSLQT------LPSPPA 362 Score = 35.0 bits (79), Expect = 0.37 Identities = 42/151 (27%), Positives = 49/151 (32%), Gaps = 28/151 (18%) Query: 454 PPRSGPQS------------PAPAAPAQP--GATLAPPTPPRPRDGGTPRHSRALSWAAR 499 PP GP+ P+PAA +P G L P TP S A S + Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS- 258 Query: 500 AARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRP 559 R P PA P + +RP Q PR A A P P P Sbjct: 259 ---------ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309 Query: 560 LPRVQLRAPPRPPRPHGRRTGGPQATQPRPP 590 +A P PP P T P P PP Sbjct: 310 ---SGTKARPVPP-PDNAATPLPATLPPSPP 336 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 2e-09 Identities = 69/247 (27%), Positives = 91/247 (36%), Gaps = 39/247 (15%) Query: 431 PDDFLDDEDEG---------ELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPR 481 PDDF D E G L S+ + P + G P P PG PP Sbjct: 100 PDDFADKEVTGTSSLVNGNLRLYSSVG--DLRPGQYGQDLLIPPPP--PGPAPGPPQDIS 155 Query: 482 PRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAP 541 GG+P S + A P PL L PPP P++ PPP V P +SP P Sbjct: 156 EPPGGSPLPSPP----STAPPPPPLLL--EPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209 Query: 542 APRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPA-----RAQAT 596 P PP P + P P V APP P PH T+ PP ++ Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPH------TVGTRLFPPGGVTKWKSDVA 263 Query: 597 QGGREGQARTLGP---AAPTVDSNLSSEARPVTSFLSLSQVSGP------QLPGEGEEEE 647 GR+ +A P A S L P +F +V P +P + +E Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 648 EGEDDGA 654 +++GA Sbjct: 324 PRKEEGA 330 Score = 33.1 bits (74), Expect = 1.4 Identities = 48/207 (23%), Positives = 67/207 (32%), Gaps = 27/207 (13%) Query: 436 DDEDEGELLDSLEPTEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSR 492 D E + L+ T A PR G Q+ A P L PP PP P Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP----- 409 Query: 493 ALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPG 552 AA PLP A PP + P P + P P+P P Sbjct: 410 ----LPPAAPPLPCAQKAAHPPAGFTKTPKSS------SPALKPKPNPPSPENTASSAPV 459 Query: 553 VFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP 612 + P + + LR RR + +P P Q+ +G + GP P Sbjct: 460 DWRDPSQMEK--LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK-------GPRLP 510 Query: 613 TVDSNLSSEARPVTSFLSLSQVSGPQL 639 ++ LS A+ + + G L Sbjct: 511 EKETLLSLPAKDTPPGVPEKSLGGSSL 537 Score = 30.4 bits (67), Expect = 9.1 Identities = 57/218 (26%), Positives = 73/218 (33%), Gaps = 33/218 (15%) Query: 446 SLEPTEAAPPRSGPQS-PAPAAPAQPGATLAPPTPPRPRDG-GTPRHSRALSWAARAARP 503 SL+P P P++ P PA P P ATL P TPP+ G TP L + P Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIP--PKATLWPATPPKATLGPATP-----LKATSGPTTP 682 Query: 504 LPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRV 563 L G A + G P PA + P Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP-------------S 729 Query: 564 QLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEAR 623 Q R P T G +++ PP + + GG G+ L S+LS E Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPP---KTSPGG--GEVPCL-YKPHCHQSSLSREVA 783 Query: 624 PVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAAS 661 V L+ +GP GE E E G P AS Sbjct: 784 VVMPTLARGGAAGP-----GEPVEVKEPPGLPAKPPAS 816 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 62.8 bits (151), Expect = 2e-09 Identities = 69/247 (27%), Positives = 91/247 (36%), Gaps = 39/247 (15%) Query: 431 PDDFLDDEDEG---------ELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPR 481 PDDF D E G L S+ + P + G P P PG PP Sbjct: 100 PDDFADKEVTGTSSLVNGNLRLYSSVG--DLRPGQYGQDLLIPPPP--PGPAPGPPQDIS 155 Query: 482 PRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAP 541 GG+P S + A P PL L PPP P++ PPP V P +SP P Sbjct: 156 EPPGGSPLPSPP----STAPPPPPLLL--EPPPPPSMAPPPPPVLEALSPPHTLSSPSIP 209 Query: 542 APRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPA-----RAQAT 596 P PP P + P P V APP P PH T+ PP ++ Sbjct: 210 TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPH------TVGTRLFPPGGVTKWKSDVA 263 Query: 597 QGGREGQARTLGP---AAPTVDSNLSSEARPVTSFLSLSQVSGP------QLPGEGEEEE 647 GR+ +A P A S L P +F +V P +P + +E Sbjct: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323 Query: 648 EGEDDGA 654 +++GA Sbjct: 324 PRKEEGA 330 Score = 33.1 bits (74), Expect = 1.4 Identities = 48/207 (23%), Positives = 67/207 (32%), Gaps = 27/207 (13%) Query: 436 DDEDEGELLDSLEPTEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSR 492 D E + L+ T A PR G Q+ A P L PP PP P Sbjct: 355 DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP----- 409 Query: 493 ALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPG 552 AA PLP A PP + P P + P P+P P Sbjct: 410 ----LPPAAPPLPCAQKAAHPPAGFTKTPKSS------SPALKPKPNPPSPENTASSAPV 459 Query: 553 VFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP 612 + P + + LR RR + +P P Q+ +G + GP P Sbjct: 460 DWRDPSQMEK--LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK-------GPRLP 510 Query: 613 TVDSNLSSEARPVTSFLSLSQVSGPQL 639 ++ LS A+ + + G L Sbjct: 511 EKETLLSLPAKDTPPGVPEKSLGGSSL 537 Score = 30.4 bits (67), Expect = 9.1 Identities = 57/218 (26%), Positives = 73/218 (33%), Gaps = 33/218 (15%) Query: 446 SLEPTEAAPPRSGPQS-PAPAAPAQPGATLAPPTPPRPRDG-GTPRHSRALSWAARAARP 503 SL+P P P++ P PA P P ATL P TPP+ G TP L + P Sbjct: 630 SLQPKAMLGPAIPPKATPEPAIP--PKATLWPATPPKATLGPATP-----LKATSGPTTP 682 Query: 504 LPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRV 563 L G A + G P PA + P Sbjct: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP-------------S 729 Query: 564 QLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEAR 623 Q R P T G +++ PP + + GG G+ L S+LS E Sbjct: 730 QARGEGSPSEATRLPTQGARSSAAFPP---KTSPGG--GEVPCL-YKPHCHQSSLSREVA 783 Query: 624 PVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAAS 661 V L+ +GP GE E E G P AS Sbjct: 784 VVMPTLARGGAAGP-----GEPVEVKEPPGLPAKPPAS 816 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 62.0 bits (149), Expect = 3e-09 Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 43/224 (19%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPP 513 PP+ GP P P Q PP RP G +H L A PLP R P Sbjct: 462 PPQGGPPQPGPGPQRQ-----GPPLQQRPPPQGQ-QHLSGLG--PPAGSPLPQ---RLPS 510 Query: 514 PRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPR 573 P A +QP + G+++ P A P AP P R PP P Sbjct: 511 PTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP------------PAAR-----PPASPS 553 Query: 574 PHGRRTGGPQATQ------PRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTS 627 P R+ G PQAT+ P PP + A GG++ Q P P + +S+A PV Sbjct: 554 PQ-RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612 Query: 628 FLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPA 671 +GP + G G P + A + S++ PA Sbjct: 613 -------TGPPTTQQPRPSGPG-PAGRPKPQLAQKPSQDVPPPA 648 Score = 47.4 bits (111), Expect = 7e-05 Identities = 43/147 (29%), Positives = 55/147 (37%), Gaps = 17/147 (11%) Query: 450 TEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPL 506 ++AAPP G P P P A P +P R G P+ +R S + P P Sbjct: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTS----VSGPAPP 575 Query: 507 FLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRA-------PWPPFPGVFLHPRP 559 APP + PP K P ++AS P PR P P PG RP Sbjct: 576 KASGAPPGGQQRQGPPQKP-PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPA--GRP 632 Query: 560 LPRVQLRAPPRPPRPHGRRTGGPQATQ 586 P++ + P P GGP Q Sbjct: 633 KPQLAQKPSQDVPPPATAAAGGPPHPQ 659 Score = 31.2 bits (69), Expect = 5.3 Identities = 39/137 (28%), Positives = 53/137 (38%), Gaps = 26/137 (18%) Query: 451 EAAPPRSGPQSPAPAAPAQPGATLAPP------TPPR--PRDGGTPRHSRALSWAARAA- 501 +A PP++ Q+ + PA P A+ APP PP+ P G R + R Sbjct: 557 QAGPPQATRQTSV-SGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPRTGP 615 Query: 502 ----RPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHP 557 +P P G A P+P + Q +P Q P A A A PP P + Sbjct: 616 PTTQQPRPSGPGPAGRPKPQLAQ----------KPSQDVPPPATA-AAGGPPHPQL-NKS 663 Query: 558 RPLPRVQLRAPPRPPRP 574 + L P PPRP Sbjct: 664 QSLTNAFNLPEPAPPRP 680 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 62.0 bits (149), Expect = 3e-09 Identities = 64/224 (28%), Positives = 85/224 (37%), Gaps = 43/224 (19%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPP 513 PP+ GP P P Q PP RP G +H L A PLP R P Sbjct: 462 PPQGGPPQPGPGPQRQ-----GPPLQQRPPPQGQ-QHLSGLG--PPAGSPLPQ---RLPS 510 Query: 514 PRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPR 573 P A +QP + G+++ P A P AP P R PP P Sbjct: 511 PTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAP------------PAAR-----PPASPS 553 Query: 574 PHGRRTGGPQATQ------PRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTS 627 P R+ G PQAT+ P PP + A GG++ Q P P + +S+A PV Sbjct: 554 PQ-RQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612 Query: 628 FLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPA 671 +GP + G G P + A + S++ PA Sbjct: 613 -------TGPPTTQQPRPSGPG-PAGRPKPQLAQKPSQDVPPPA 648 Score = 50.1 bits (118), Expect = 1e-05 Identities = 47/156 (30%), Positives = 61/156 (39%), Gaps = 18/156 (11%) Query: 450 TEAAPPRSGP---QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPL 506 ++AAPP G P P P A P +P R G P+ +R S + P P Sbjct: 520 SQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPPQATRQTS----VSGPAPP 575 Query: 507 FLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRA-------PWPPFPGVFLHPRP 559 APP + PP K P ++AS P PR P P PG RP Sbjct: 576 KASGAPPGGQQRQGPPQKP-PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPA--GRP 632 Query: 560 LPRVQLRAPPRPPRPHGRRTGGPQATQPR-PPARAQ 594 P++ + P P GGP Q + PA+AQ Sbjct: 633 KPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668 >gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens] Length = 882 Score = 61.2 bits (147), Expect = 5e-09 Identities = 40/145 (27%), Positives = 68/145 (46%), Gaps = 16/145 (11%) Query: 889 GNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMR--- 945 G F R GL+ A D +++ CD+ + F + L R + ++G+ + P++ Sbjct: 693 GEFSRGLGLEMA-SAQFDNDTLLLFCDVDLIFREDFLQRCRDNTIQGQQVYYPIIFSQYD 751 Query: 946 ---LSCGSSPRDPH-------GYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWE 995 + G+ P D + G+W G+G+ IYKSD GG +T WG ED + Sbjct: 752 PKVTNGGNPPTDDYFIFSKKTGFWRDYGYGITCIYKSDLLGAGGFDTS--IQGWGLEDVD 809 Query: 996 LLDRVLQAGLEVERLRLRNFYHHYH 1020 L ++V+ +GL R + H +H Sbjct: 810 LYNKVILSGLRPFRSQEVGVVHIFH 834 Score = 37.7 bits (86), Expect = 0.057 Identities = 32/104 (30%), Positives = 44/104 (42%), Gaps = 5/104 (4%) Query: 575 HGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARP-VTSFLSLSQ 633 +GR GP+A +P + Q+ R Q ++ PA + EA P +TSF S Sbjct: 48 YGRSAAGPRAGAQQPLPQPQS----RPRQEQSPPPARQDLQGPPLPEAAPGITSFRSSPW 103 Query: 634 VSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRWRE 677 P L E G PG AA + EE G A G+ R+ Sbjct: 104 QQPPPLQQRRRGREPEGATGLPGAPAAEGEPEEEDGGAAGQRRD 147 Score = 32.0 bits (71), Expect = 3.1 Identities = 41/150 (27%), Positives = 50/150 (33%), Gaps = 22/150 (14%) Query: 441 GELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARA 500 G L S AA PR+G Q P P ++P +PP P R G P A + Sbjct: 41 GSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPP-PARQDLQGPPLPEAAPGITSFR 99 Query: 501 ARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL 560 + P +QPPP R R + A+ AP A P Sbjct: 100 SSPW--------------QQPPPLQQRRRGREPEGATGLPGAPAAEGEP------EEEDG 139 Query: 561 PRVQLRAPPRPPRPH-GRRTGGPQATQPRP 589 R RP H G GG A RP Sbjct: 140 GAAGQRRDGRPGSSHNGSGDGGAAAPSARP 169 >gi|11386183 WAS protein family, member 2 [Homo sapiens] Length = 498 Score = 60.8 bits (146), Expect = 6e-09 Identities = 61/220 (27%), Positives = 78/220 (35%), Gaps = 45/220 (20%) Query: 452 AAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRA 511 A P RS SP+ PA P + PP P+ G P P P Sbjct: 287 AGPKRSSVVSPSHPPPAPPLGS-----PPGPKPGFAPP-------------PAP-----P 323 Query: 512 PPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRP 571 PPP P + PPP V PG P P+ +PP P P P P P P Sbjct: 324 PPPPPMIGIPPPPPPVGFGSPGTPPPPSPPS----FPPHPDFAAPPPPPPPPAADYPTLP 379 Query: 572 PRPHGRRTGG--PQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFL 629 P P + TGG P P PP G +GQ P + LS +P +S Sbjct: 380 PPPLSQPTGGAPPPPPPPPPPGPPPPPFTGADGQ--------PAIPPPLSDTTKPKSSLP 431 Query: 630 SLSQVSGPQLPG--------EGEEEEEGEDDGAPGDEAAS 661 ++S L EE+ E E G++ A+ Sbjct: 432 AVSDARSDLLSAIRQGFQLRRVEEQREQEKRDVVGNDVAT 471 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/126 (26%), Positives = 38/126 (30%), Gaps = 32/126 (25%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508 P P + P P+ P P PP PP P A + PL Sbjct: 338 PVGFGSPGTPPPPSPPSFPPHPDFAAPPPPPPPP----------AADYPTLPPPPLSQPT 387 Query: 509 GRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAP 568 G APPP PPP P P P PPF G P P + Sbjct: 388 GGAPPP------PPP----------------PPPPGPPPPPFTGADGQPAIPPPLSDTTK 425 Query: 569 PRPPRP 574 P+ P Sbjct: 426 PKSSLP 431 >gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD subunit [Homo sapiens] Length = 551 Score = 60.1 bits (144), Expect = 1e-08 Identities = 54/147 (36%), Positives = 57/147 (38%), Gaps = 28/147 (19%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508 P A P GP P PA P L PP PP P G P + L P PL Sbjct: 218 PGPAGP--GGPPPPFPAGQTPPRPPLGPPGPPGP--PGPPPPGQVL--------PPPL-- 263 Query: 509 GRAPPPRPAVEQPPPKVYVTRVRPGQ--RASPRAPAPRAPWPPFPGVFLHPRPLPRVQLR 566 A PP PPP ++ PGQ P P P P PP PG P P P Q Sbjct: 264 --AGPPNRGDRPPPPVLF-----PGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGP 316 Query: 567 APPR---PPRPHGRRTGGPQATQPRPP 590 PP PPRP G GP T PP Sbjct: 317 PPPPGPFPPRPPGPL--GPPLTLAPPP 341 Score = 56.6 bits (135), Expect = 1e-07 Identities = 59/173 (34%), Positives = 61/173 (35%), Gaps = 27/173 (15%) Query: 450 TEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPL----- 504 T PP P P P P PG L PP P G P PL Sbjct: 235 TPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQPFGQPPLGPLPP 294 Query: 505 ---PLFLGRAPPPRPAVEQ----PPPKVYVTRVRPGQRASP--RAPAPRAPWPPFPGVFL 555 P G PPP P Q PPP + R PG P AP P P PP PG Sbjct: 295 GPPPPVPGYGPPPGPPPPQQGPPPPPGPFPPR-PPGPLGPPLTLAPPPHLPGPP-PGA-- 350 Query: 556 HPRPLPRVQLRAPPRPPRPHGRRTG---GPQATQP--RPPARAQATQG--GRE 601 P P P V P PP G T GP T P RPP + G GRE Sbjct: 351 -PPPAPHVNPAFFP-PPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDYGPPGRE 401 Score = 44.3 bits (103), Expect = 6e-04 Identities = 27/78 (34%), Positives = 31/78 (39%), Gaps = 3/78 (3%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTP-PRPRDGGTP--RHSRALSWAARAARPLP 505 P + PP GP P P P P TLAPP P P G P H + +P Sbjct: 312 PQQGPPPPPGPFPPRPPGPLGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMP 371 Query: 506 LFLGRAPPPRPAVEQPPP 523 R PPP +PPP Sbjct: 372 TSDSRGPPPTDPYGRPPP 389 Score = 33.5 bits (75), Expect = 1.1 Identities = 34/109 (31%), Positives = 37/109 (33%), Gaps = 14/109 (12%) Query: 509 GRAPPPRPAVEQPPPKVYVTRVR-----PGQRASPRAPAPRAPWPPFPGVFLHPRPLPRV 563 G+A PP + P+ R R PG P P P PPFP PRP Sbjct: 184 GKAGPPGGSSRAAFPQGGRGRGRFPGAVPGGDRFPGPAGPGGPPPPFPAGQTPPRP---- 239 Query: 564 QLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP 612 P PP P G G P Q PP A G L P P Sbjct: 240 ----PLGPPGPPG-PPGPPPPGQVLPPPLAGPPNRGDRPPPPVLFPGQP 283 Score = 30.4 bits (67), Expect = 9.1 Identities = 33/125 (26%), Positives = 37/125 (29%), Gaps = 26/125 (20%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508 P P GP P P PG P PPRP PL L Sbjct: 299 PVPGYGPPPGPPPPQQGPPPPPG-----PFPPRP------------------PGPLGPPL 335 Query: 509 GRAPPPR---PAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQL 565 APPP P PPP +V + P + PP + P P R Sbjct: 336 TLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGRPPPYDRGDY 395 Query: 566 RAPPR 570 P R Sbjct: 396 GPPGR 400 >gi|4826998 splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) [Homo sapiens] Length = 707 Score = 59.3 bits (142), Expect = 2e-08 Identities = 84/300 (28%), Positives = 103/300 (34%), Gaps = 38/300 (12%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508 P P +SGP+ P P P PP P P+ P H P P Sbjct: 46 PMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQ--PPPHQPP-------PHPQPHQQ 96 Query: 509 GRAPPP-----RPAVEQPP-PKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 + PPP +P V Q P P V P ++P A P + PP G P P P Sbjct: 97 QQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPA 156 Query: 563 VQLR---APPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLS 619 V APP P G T PQA P PP A G G + GP P + Sbjct: 157 VTSAPPGAPPPTPPSSGVPTTPPQAGGPPPP--PAAVPGPGPGPKQGPGPGGPK-GGKMP 213 Query: 620 SEARPVTSFLSLSQVSG-PQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRWRED 678 +P LS G P+ P G E G P GP G E+ Sbjct: 214 GGPKP-GGGPGLSTPGGHPKPPHRGGGEPRGGRQHHPPYHQQHHQGPPPGGP--GGRSEE 270 Query: 679 AIDWQRTFSVGAVDFELLRSDWNDL---RCNV-SGNLQLPEAEAVDVTAQYMERLNARHG 734 I F + LLR RC + GNL D+T +RL A++G Sbjct: 271 KISDSEGFK---ANLSLLRRPGEKTYTQRCRLFVGNL------PADITEDEFKRLFAKYG 321 Score = 36.2 bits (82), Expect = 0.17 Identities = 31/119 (26%), Positives = 45/119 (37%), Gaps = 5/119 (4%) Query: 521 PPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPH--GRR 578 PPP + + + R P P+ P PP P +P P+ + PP+ P PH Sbjct: 34 PPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQ---QPPPQQPPPHQPPPH 90 Query: 579 TGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGP 637 Q QP PP + + +G G + S+ + A P TS GP Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGP 149 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 59.3 bits (142), Expect = 2e-08 Identities = 53/224 (23%), Positives = 66/224 (29%), Gaps = 33/224 (14%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPP----------TPPRPRDGGTPRHSRALSWAARAARP 503 PP+ P +PA P+ G PP TPP P+ G + A P Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203 Query: 504 LPLFLGRAPPPRPAVEQP---PPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL 560 P P P+ A P PP P + +P PA P P P+ Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263 Query: 561 PRVQLRAPPR--------------------PPRPHGRRTGGPQATQPRPPARAQATQGGR 600 P PP PP P G P P PPA + G Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323 Query: 601 EGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGPQLPGEGE 644 G G P + S + P + S GP P E Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367 Score = 58.5 bits (140), Expect = 3e-08 Identities = 61/208 (29%), Positives = 75/208 (36%), Gaps = 28/208 (13%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPP----------TPPRPRDGGTPRHSRALSWAARAARP 503 PP+ P PA P+ G PP TPP P+ G + A P Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318 Query: 504 LPLFLGRAPPPR-----PAVEQPPPKVYVT--RVRPGQRASPRAPAPR-APWPP--FPGV 553 P PPP+ PAV P PK T P + P P+ + P PP P Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378 Query: 554 FLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQAR-TLGPAAP 612 P P R P P P G T A P P +A AT REG A + G P Sbjct: 1379 KGGPAMTPPSPKRG-PAIPSPKGDPTS--PAVIPLSPKKAPATPVTREGAATPSKGDLTP 1435 Query: 613 TVDSNLSSEARPVTSFLSLSQVSGPQLP 640 + +S + P TS + GP P Sbjct: 1436 PAVTPVSLKKAPATS----APKGGPATP 1459 Score = 52.0 bits (123), Expect = 3e-06 Identities = 77/279 (27%), Positives = 98/279 (35%), Gaps = 66/279 (23%) Query: 449 PTEAAPP--RSGPQSPAP-AAPAQPGATLAPPTP-------PRPRDGGTPRHSRALS-WA 497 P A PP + GP +P+P AP P T PP+P P P+ TP + S Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVT--PPSPKGSPAATPFPKGASTPPAATPPSPKG 1045 Query: 498 ARAARPLPLFLGRAPPPRPAVEQPPPK------------VYVTRVRPGQRASPRAPAPR- 544 + AA PLP + P PA P PK P + P P+P+ Sbjct: 1046 SPAATPLP----KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKG 1101 Query: 545 -----APWPPFP--GVFLHP-RPLPRVQLRAPPRP------PRPHGRRTGGPQATQPRP- 589 A PP P G+ P + P PP P P P G T P AT P P Sbjct: 1102 APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT-TPAATPPSPK 1160 Query: 590 -----------PARAQATQGGREGQARTLGP-AAPTVDSNLSSEARPVTSFLSLSQVSGP 637 P AT +G T P APT + ++ P + S P Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA--ATPPSPKGGLATPSPKGAP 1218 Query: 638 QLPGEGEEEEEG-----EDDGAPGDEAASEDSEEAAGPA 671 P +G GAP AA+ S + GPA Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-GGPA 1256 Score = 50.4 bits (119), Expect = 8e-06 Identities = 71/257 (27%), Positives = 94/257 (36%), Gaps = 39/257 (15%) Query: 445 DSLEPTEAAPPRSGPQSPAPAA--PAQP-GATLAP---PTP-----PRPRDGGT---PRH 490 DS T + P S +P P+A P P G TL P PTP P P++G P+ Sbjct: 848 DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907 Query: 491 SRALSWAARA-----ARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRA 545 + ALS + + A P P + +P P+ A P + P + AP P A Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967 Query: 546 PWPPFP---GVFLHPRPLPRVQLRAPPRP------PRPHGRRTGGPQATQPRPPARAQAT 596 PP P P+ P PP P P P G T P T P P AT Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT-PPAVTPPSPKGSPAAT 1026 Query: 597 QGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSLSQVSGP--QLPGEGEEEEEGEDDGA 654 + G + P + S + P + L + P LP GA Sbjct: 1027 PFPK-------GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079 Query: 655 PGDEAASEDSEEAAGPA 671 P AA+ S + GPA Sbjct: 1080 PTPPAATPPSPK-GGPA 1095 Score = 50.4 bits (119), Expect = 8e-06 Identities = 63/222 (28%), Positives = 79/222 (35%), Gaps = 25/222 (11%) Query: 455 PRSGPQSPAP-AAPAQPGATLAPPTP------PRPRDGGTPRHSRALSWAARAARPLPLF 507 P+ P SP+P AP P AT PP+P P P+ TP + S A P P Sbjct: 927 PKGIPASPSPKGAPTPPAAT--PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP-- 982 Query: 508 LGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRA 567 + P PA P PK P + AP P A PP P P P+ Sbjct: 983 --KGAPTPPAATPPSPKG-----GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035 Query: 568 P-PRPPRPHG--RRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP--TVDSNLSSEA 622 P PP P G T P+ P A + +GG + P P T S A Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095 Query: 623 RPVTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDS 664 P + + P P G + GAP AA+ S Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHK--GAPTTPAATPPS 1135 Score = 44.7 bits (104), Expect = 5e-04 Identities = 45/177 (25%), Positives = 61/177 (34%), Gaps = 28/177 (15%) Query: 453 APPRSGPQSPAPAAPAQPGATLAPP----------TPPRPRDGGTPRHSRALSWAARAAR 502 +PP+ P PA P+ G+ PP TPP P+ GTP L +++ Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK--GTP----TLPATTPSSK 1357 Query: 503 PLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 P P P P K P + P P+P+ P P V +P Sbjct: 1358 GGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD-PTSPAV------IPL 1410 Query: 563 VQLRAPPRPPRPHGRRTGG-----PQATQPRPPARAQATQGGREGQARTLGPAAPTV 614 +AP P G T P A P +A AT + G A PT+ Sbjct: 1411 SPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL 1467 Score = 44.3 bits (103), Expect = 6e-04 Identities = 54/195 (27%), Positives = 67/195 (34%), Gaps = 16/195 (8%) Query: 453 APPRSGPQSPAPAAPAQPG-ATLAPPTPPRPRDGGTPRHSRALSWAARA-ARPLPLFLGR 510 AP S P+ PA P+ G TL TPP P++ P+ S +A A P P+ Sbjct: 1446 APATSAPKG-GPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM---- 1500 Query: 511 APPPRPAVEQPPPKVYVTRVRPGQRASPRAP-----APRAPWPPFPGVFLHPRPLPRVQL 565 P PAV PK P R P AP + + P P L P + Sbjct: 1501 GAPTLPAVIPSSPK--EVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSP 1558 Query: 566 RAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPV 625 + P P P PPA +T G L P P V S EA Sbjct: 1559 KKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIP--PAVTSPSPKEAPTP 1616 Query: 626 TSFLSLSQVSGPQLP 640 + S GP P Sbjct: 1617 PAVTPPSPEKGPATP 1631 Score = 34.7 bits (78), Expect = 0.48 Identities = 48/180 (26%), Positives = 65/180 (36%), Gaps = 35/180 (19%) Query: 446 SLEPTEA-APPRSGPQSP--APAAPAQPGATLAPP-TPPRPRDGGTPRHSRALSWAA--- 498 S P EA PP P SP PA PA G +PP TP +D T S A Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVP 1666 Query: 499 RAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPR 558 +A++ LP ++ P + V P ++P AP P Sbjct: 1667 QASKGLP------------AKKGPTALKEVLVAPAPESTPIITAPTRKGP---------- 1704 Query: 559 PLPRVQLRAPPRPPRPHGRR-TGGPQAT-QPRPPARAQ----ATQGGREGQARTLGPAAP 612 + +PP P P + + GP +T P P Q T G++ GP AP Sbjct: 1705 QTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAP 1764 Score = 32.3 bits (72), Expect = 2.4 Identities = 54/207 (26%), Positives = 72/207 (34%), Gaps = 35/207 (16%) Query: 441 GELLDSLEPTEAAPPRSG------PQSPA---PAAPAQPGATLAPPTPPRPRDGGTPRHS 491 GE +++ TE P+ P S A AA QPG TL PP P P+ Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQ-------- 54 Query: 492 RALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPA--PRAPWPP 549 + AA A P P A P +E P P+ P +P AP P PP Sbjct: 55 QCPLSAANQASPFPSPSTIASTP---LEVPFPQSSSGTALP-LGTAPEAPTFLPNLIGPP 110 Query: 550 F-PGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQ----------PRPPARAQATQG 598 P P+ L+ P P P + Q PP+ A A G Sbjct: 111 ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESG 170 Query: 599 GREGQARTLGPAAPTVDSN-LSSEARP 624 + + P+ P + N + SE P Sbjct: 171 SVITLSAPIAPSEPKTNLNKVPSEVVP 197 Score = 32.3 bits (72), Expect = 2.4 Identities = 58/218 (26%), Positives = 76/218 (34%), Gaps = 44/218 (20%) Query: 448 EPT-EAAPPRSGPQSP-------------APAAPAQPGA-TLAPPTPPRPRD-GGTP--R 489 +PT A P S + P APA PA GA TL P P++ TP R Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523 Query: 490 HSRALSWAARAARPLPLFLGRAP-----PPRPAVEQP--PPKVYVTRVRPGQRASPRAPA 542 A ++ P L AP PP V P P + + P +S A + Sbjct: 1524 RDPIAPTATLLSKKTPATL--APKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581 Query: 543 PRAPWP------PFPGVFLHP----RPLPRVQLRAPP--RPPRPH-GRRTGGPQATQPRP 589 P A P P P L P P P+ + PP PP P G T P+ T P Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPK-EAPTPPAVTPPSPEKGPATPAPKGTPTSP 1640 Query: 590 PARAQATQGGREGQART---LGPAAPTVDSNLSSEARP 624 P + + A +G P L ++ P Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP 1678 Score = 32.0 bits (71), Expect = 3.1 Identities = 27/85 (31%), Positives = 34/85 (40%), Gaps = 16/85 (18%) Query: 449 PTEAAPPRSG--PQSP-----APAAPAQPGAT--LAPPTPPRPRDGGTPRHSRALSWAAR 499 P PP+ P SP +P+ P P L P PP P GG P S ++ Sbjct: 1806 PVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVN---- 1861 Query: 500 AARPLPLFLGRAPPPRPAVEQPPPK 524 P P G P P P+ +QP K Sbjct: 1862 --MPTPKSAG-IPVPTPSAKQPVTK 1883 Score = 31.2 bits (69), Expect = 5.3 Identities = 50/201 (24%), Positives = 61/201 (30%), Gaps = 44/201 (21%) Query: 446 SLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLP 505 +L P EA P + PA P AP TP P + + A + + L Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELL 1600 Query: 506 LFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQL 565 + PAV P PK AP P A PP P Sbjct: 1601 I--------PPAVTSPSPK--------------EAPTPPAVTPPSP-------------- 1624 Query: 566 RAPPRPPRPHGRRTGGPQA-----TQPRPPARAQATQGGREGQARTLGPA--APT-VDSN 617 P P P G T P P PA G QA PA PT + Sbjct: 1625 EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEV 1684 Query: 618 LSSEARPVTSFLSLSQVSGPQ 638 L + A T ++ GPQ Sbjct: 1685 LVAPAPESTPIITAPTRKGPQ 1705 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 58.9 bits (141), Expect = 2e-08 Identities = 69/241 (28%), Positives = 85/241 (35%), Gaps = 45/241 (18%) Query: 453 APPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAP 512 +PP P SP + P P AT PP+ P P A+ P +AP Sbjct: 445 SPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502 Query: 513 PPRPA----VEQPPPKVYVTRVRPGQRASPRAPAP---RAPWPPFPGVFLHPRPLPRVQ- 564 PP A + +PPP+ P +A P PA +AP+ P + + P P Q Sbjct: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQA 562 Query: 565 --------LRAPPRPPRPHGRRTGGPQATQP-RPPARAQATQGGREGQARTLGPAAPTVD 615 L+ PP PP P P RPP T L P P Sbjct: 563 PPVLAAPLLQVPPSPP-------ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615 Query: 616 SNLSSEARPVTSFLSLSQVSGPQLPGEGE------EEEEGEDDGAPGDEAAS--EDSEEA 667 S S S +SGP L G EE G D G G AAS D+E A Sbjct: 616 SRSPS-----------STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664 Query: 668 A 668 A Sbjct: 665 A 665 Score = 48.5 bits (114), Expect = 3e-05 Identities = 59/207 (28%), Positives = 73/207 (35%), Gaps = 45/207 (21%) Query: 444 LDSLEPTEAAPPRS------GPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWA 497 L +L P + PPR GP S +P A P A L PP P + S Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT-----LPATPHSSSLT 331 Query: 498 ARAARPLPLF--LGRAPPPRPAVEQPP-------------PKVYVTR-VRPGQRASPRA- 540 + A PLPL APP + PP P + T P SP A Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391 Query: 541 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGR 600 P P+AP P + L P L+APP PP P + P +A Sbjct: 392 PPPQAP----PALALPP-------LQAPPSPP------ASPPLSPLATPSPQAPNALAVH 434 Query: 601 EGQARTLGPAAPTVDSNLSSEARPVTS 627 QA P +P V + S A P S Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVS 461 Score = 42.0 bits (97), Expect = 0.003 Identities = 40/129 (31%), Positives = 50/129 (38%), Gaps = 9/129 (6%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRH--SRALSWAARA----ARPLPLF 507 PP GP+ +A +P RP GG + SR+LS +A AR P Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS- 258 Query: 508 LGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRA 567 R P PA P + +RP Q PR A A P P P +Q +A Sbjct: 259 -ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317 Query: 568 PPR-PPRPH 575 PP P PH Sbjct: 318 PPTLPATPH 326 Score = 41.2 bits (95), Expect = 0.005 Identities = 54/188 (28%), Positives = 67/188 (35%), Gaps = 20/188 (10%) Query: 450 TEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGT---PRHSRALSWAARAARPLPL 506 + +A P S P P+A P A A P+ P+P+ P+ + AA A PL Sbjct: 243 SSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Query: 507 FLGRAPPPRPAVE-QPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQL 565 P P A++ Q PP + T P P AP P L P P Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP---- 357 Query: 566 RAPPRPPRPHGRRTGGP--QATQ---PRPPARAQATQGGREGQARTL----GPAAPTVDS 616 P PP G P QAT P PP AT + A L P +P Sbjct: 358 --PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 415 Query: 617 NLSSEARP 624 LS A P Sbjct: 416 PLSPLATP 423 Score = 40.0 bits (92), Expect = 0.011 Identities = 53/194 (27%), Positives = 68/194 (35%), Gaps = 39/194 (20%) Query: 455 PRSGP--------QSPAPAAPAQPGATLAPP---TPPRP-----RDGGTPRHSRALSWAA 498 PR+GP ++PA PA APP T P P R GT R Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134 Query: 499 RAARPLPLFLGRAP--PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFP----- 551 R + + G+A P R A+ G R P P P P Sbjct: 135 RISAEETVARGKATEAPKRSALSA------------GARRDTSGPTPGTPSPAMARRSRA 182 Query: 552 -GVFLH-PRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGP 609 G + PRP P + R P PR T+P P AR + + GG G R Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASR 240 Query: 610 AAPTVDSNLSSEAR 623 + + + LSS AR Sbjct: 241 SLSSSATPLSSPAR 254 Score = 39.7 bits (91), Expect = 0.015 Identities = 77/302 (25%), Positives = 98/302 (32%), Gaps = 81/302 (26%) Query: 444 LDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTP-----PRPRDGGTPRHSRALSWAA 498 L +L A+ P P SP+ + P P AT P P P + +P S L Sbjct: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587 Query: 499 RAARPLP--------LFLGRAPPPRPAVEQPPPKVYVTRVRPGQRAS------------- 537 R P P L L AP P P + P G +S Sbjct: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 647 Query: 538 -PRAPAPRAPWPPFPGVFLHPR-----PLPRVQLRAPPRPPRPHGRRTG----------- 580 P A +P P HP P P + R P P P TG Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 707 Query: 581 ---GPQATQPRP----PARAQATQGGREG-------------QAR----TLGPAAPTVDS 616 GP++ P P P + T GG+ QAR LG +V Sbjct: 708 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 767 Query: 617 NLSSEARPVTSFLSLSQ-VSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRW 675 +L S T L+ ++ +G G G E G GA AA D+E LGRW Sbjct: 768 HLLSR----TLLLAAAEGAAGGSGGGPGGAEGGGVTGGA---RAALSDAE------LGRW 814 Query: 676 RE 677 E Sbjct: 815 AE 816 Score = 37.7 bits (86), Expect = 0.057 Identities = 60/234 (25%), Positives = 85/234 (36%), Gaps = 31/234 (13%) Query: 456 RSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLF-----LGR 510 ++G + PAA A T PP PRP TP R L AA A PL +G Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLG-AAGAVGRKPLAERAGGIGG 67 Query: 511 APPPRPAVEQPPPKVYVTRVR-PGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPP 569 A P A P + T R P R RAP P P P+ + Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP----PAKNTSPGPVSSPGRASGT 123 Query: 570 RPPRPHGRRTGGPQATQPRPPARAQATQGGRE------GQARTLGPAAPTVDSNLSSEAR 623 P P G++ G + + AR +AT+ + + T GP T ++ +R Sbjct: 124 TRPGPLGQK--GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 624 PVTSFLSL---SQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGR 674 + + L + + P+ P EG + +ASE S PA R Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSV---------SSASEHSTTEPSPAARR 226 >gi|85815829 SH3-domain binding protein 1 [Homo sapiens] Length = 701 Score = 58.9 bits (141), Expect = 2e-08 Identities = 58/192 (30%), Positives = 75/192 (39%), Gaps = 37/192 (19%) Query: 435 LDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLA---------PPTPPRPRDG 485 L D L P+ A P + +PAPA P LA PPRP Sbjct: 486 LQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRP--- 542 Query: 486 GTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRA 545 +P+ +R+ A + R P RP + PPP+V G R+SP AP Sbjct: 543 ASPKVTRSPPETAAPVEDMARRTKRPAPARPTM--PPPQV------SGSRSSPPAP---- 590 Query: 546 PWPPFPGVFLHPRPLPR----VQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGRE 601 P PP G P+ LPR LRAP PP P P PAR Q+ + Sbjct: 591 PLPPGSGSPGTPQALPRRLVGSSLRAPTVPP---------PLPPTPPQPARRQSRRSPAS 641 Query: 602 GQARTLGPAAPT 613 + GPA+P+ Sbjct: 642 PSPASPGPASPS 653 Score = 47.8 bits (112), Expect = 5e-05 Identities = 50/160 (31%), Positives = 62/160 (38%), Gaps = 23/160 (14%) Query: 449 PTEAAPPRS---GPQSPAPAAPAQP-----GATLAPPTPPRPRDGGTPRHSRALSWAARA 500 P AAP + PAPA P P G+ +PP PP P G+P +AL Sbjct: 552 PETAAPVEDMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQAL------ 605 Query: 501 ARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL 560 R L RAP P + PP+ R R SP +P+P +P P P P Sbjct: 606 PRRLVGSSLRAPTVPPPLPPTPPQ----PARRQSRRSPASPSPASPGPASPSPVSLSNP- 660 Query: 561 PRVQLRAPP----RPPRPHGRRTGGPQATQPRPPARAQAT 596 +V L A P G T QPRP + A T Sbjct: 661 AQVDLGAATAEGGAPEAISGVPTPPAIPPQPRPRSLASET 700 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 58.5 bits (140), Expect = 3e-08 Identities = 71/230 (30%), Positives = 80/230 (34%), Gaps = 46/230 (20%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFL 508 P+ AAPP P SP + P P AT P PP P + L A + P Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPP-------PLAAPPLQLAKPPPQAPPAL- 484 Query: 509 GRAPPPRPAVEQPPPKVYVTRVRPGQRA-SPRAPAPRAPWPPFPGVFLHPRPLPRVQLRA 567 A PP A+ PP PGQ SP A P +P P P L L+ Sbjct: 485 --ATPPLQALPSPPASF------PGQAPFSPSASLPMSPLATPPP--QAPPVLAAPLLQV 534 Query: 568 PPRPPRPHGRRTGGPQATQP-RPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVT 626 PP PP P P RPP T L P P S S Sbjct: 535 PPSPP-------ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS------ 581 Query: 627 SFLSLSQVSGPQLPGEGE------EEEEGEDDGAPGDEAAS--EDSEEAA 668 S +SGP L G EE G D G G AAS D+E AA Sbjct: 582 -----STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626 Score = 52.4 bits (124), Expect = 2e-06 Identities = 56/196 (28%), Positives = 73/196 (37%), Gaps = 20/196 (10%) Query: 444 LDSLEPTEAAPPRS------GPQSPAPAAPAQPGATLAPPTPPR----PRDGGTPRHSRA 493 L +L P + PPR GP S +P A P A +P PP P TP Sbjct: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Query: 494 LSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPA--PRAPW-PPF 550 S + + FL PP + PPP+ P +A P PA P +P P Sbjct: 328 TSLGSPTLQATHSFL--PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385 Query: 551 PGVFLHPRPLPRVQLRAP-PRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLG- 608 P P L L+AP PP P + P A+ P P+ +Q A L Sbjct: 386 PQA---PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 442 Query: 609 PAAPTVDSNLSSEARP 624 P +P +S A P Sbjct: 443 PPSPPASPPMSPSATP 458 Score = 44.3 bits (103), Expect = 6e-04 Identities = 57/195 (29%), Positives = 75/195 (38%), Gaps = 21/195 (10%) Query: 454 PPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRH--SRALSWAARA----ARPLPLF 507 PP GP+ +A +P RP GG + SR+LS +A AR P Sbjct: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS- 249 Query: 508 LGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRA 567 R P PA P + +RP Q PR A A P L PL A Sbjct: 250 -ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP------LSSSPLATPSPSA 302 Query: 568 PPRPPRPHGRRT-GGPQATQPRPPARAQATQGGREGQA-RTLGPAAPTVDSNLSSEARPV 625 PP P P +T P AT PP++A + G QA + P+ P S L++ Sbjct: 303 PPSPSAPPSLQTLPSPPAT---PPSQATTSLGSPTLQATHSFLPSPPL--SPLATPPPQA 357 Query: 626 TSFLSLSQVSGPQLP 640 L+L + P P Sbjct: 358 PPALALPPLQAPPSP 372 Score = 39.7 bits (91), Expect = 0.015 Identities = 77/302 (25%), Positives = 98/302 (32%), Gaps = 81/302 (26%) Query: 444 LDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTP-----PRPRDGGTPRHSRALSWAA 498 L +L A+ P P SP+ + P P AT P P P + +P S L Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 Query: 499 RAARPLP--------LFLGRAPPPRPAVEQPPPKVYVTRVRPGQRAS------------- 537 R P P L L AP P P + P G +S Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608 Query: 538 -PRAPAPRAPWPPFPGVFLHPR-----PLPRVQLRAPPRPPRPHGRRTG----------- 580 P A +P P HP P P + R P P P TG Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 668 Query: 581 ---GPQATQPRP----PARAQATQGGREG-------------QAR----TLGPAAPTVDS 616 GP++ P P P + T GG+ QAR LG +V Sbjct: 669 ETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 728 Query: 617 NLSSEARPVTSFLSLSQ-VSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEEAAGPALGRW 675 +L S T L+ ++ +G G G E G GA AA D+E LGRW Sbjct: 729 HLLSR----TLLLAAAEGAAGGSGGGPGGAEGGGVTGGA---RAALSDAE------LGRW 775 Query: 676 RE 677 E Sbjct: 776 AE 777 Score = 37.7 bits (86), Expect = 0.057 Identities = 49/191 (25%), Positives = 64/191 (33%), Gaps = 23/191 (12%) Query: 451 EAAPPRSGPQSPAPAAPAQPGATLAPPTPPR-----PRDGGTPRHSRALSWAARAARPLP 505 E A G P A A P T PP R P +P + A+ RP P Sbjct: 60 ERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 119 Query: 506 L------FLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFP------GV 553 L R + P + + + G R P P P P G Sbjct: 120 LGQKGLRISAEETVARGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176 Query: 554 FLH-PRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAP 612 + PRP P + R P PR T+P P AR + + GG G R + Sbjct: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLS 234 Query: 613 TVDSNLSSEAR 623 + + LSS AR Sbjct: 235 SSATPLSSPAR 245 Score = 37.0 bits (84), Expect = 0.097 Identities = 48/193 (24%), Positives = 63/193 (32%), Gaps = 19/193 (9%) Query: 450 TEAAPPRSGPQSPAPAAPAQPGATLAPPTPP-------RPRDGGTPRHSRALSWAARAAR 502 + +A P S P P+A P A P P RP PR A + ++ Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 Query: 503 PLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 PL APP A PP + P S + +P FL PL Sbjct: 294 PLATPSPSAPPSPSA----PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349 Query: 563 VQLRAPPRPPR---PHGRRTGGPQATQPRPPARAQATQGGRE-----GQARTLGPAAPTV 614 + P PP P + P A+ P P + Q QA P +P V Sbjct: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409 Query: 615 DSNLSSEARPVTS 627 + S A P S Sbjct: 410 QAPFSPPASPPVS 422 Score = 36.2 bits (82), Expect = 0.17 Identities = 52/191 (27%), Positives = 63/191 (32%), Gaps = 39/191 (20%) Query: 456 RSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAAR------------- 502 ++G + PAA A T PP PRP TP R L A R Sbjct: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 503 PLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 +P RA P R +PP R P + SP + P P PL + Sbjct: 69 TIPESAPRAGPTR--TSRPPASGRGERAPPAKNTSPGPVSS----PGRASGTTRPGPLGQ 122 Query: 563 VQLR--------------APPRPPRPHGRR--TGGPQATQPRPP----ARAQATQGGREG 602 LR AP R G R T GP P P +RA T+ G Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 Query: 603 QARTLGPAAPT 613 A + P PT Sbjct: 183 PAPSARPRPPT 193 >gi|23592228 extraembryonic, spermatogenesis, homeobox 1-like [Homo sapiens] Length = 406 Score = 58.5 bits (140), Expect = 3e-08 Identities = 50/137 (36%), Positives = 59/137 (43%), Gaps = 13/137 (9%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRH---SRALSWAARAARPLP 505 P PPR P AP PG+ +AP PP PR P + W A P+P Sbjct: 257 PMVPMPPRPPIAPMPPMAPVPPGSRMAP-VPPGPRMAPVPPWPPMAPVPPWPPMA--PVP 313 Query: 506 LFLGRAP-PPRPAVEQPPPKVYVTRVRPGQRASPRAPA-PRAPWPPFPGVFLHPRPLPRV 563 AP PP P + + PP + RV PG +P P P AP PP P + PLP Sbjct: 314 TGPPMAPVPPGPPMARVPPGPPMARVPPGPPMAPLPPGPPMAPLPPGPPM----APLPPG 369 Query: 564 QLRAPPRPPRPHGRRTG 580 A P PPR H TG Sbjct: 370 PPMA-PLPPRSHVPHTG 385 Score = 40.8 bits (94), Expect = 0.007 Identities = 45/151 (29%), Positives = 53/151 (35%), Gaps = 48/151 (31%) Query: 498 ARAARPLPLFLGRA------------------------------PPPRPAVEQPP----- 522 A A PL +FLG A PP P V PP Sbjct: 209 ADLAHPLDMFLGGAYYAAPALDPALCVHLVPQLPRPPVLPVPPMPPRPPMVPMPPRPPIA 268 Query: 523 PKVYVTRVRPGQRASPRAPAPR-APWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGG 581 P + V PG R +P P PR AP PP+P + P+P PP P P TG Sbjct: 269 PMPPMAPVPPGSRMAPVPPGPRMAPVPPWPPM----APVP----PWPPMAPVP----TGP 316 Query: 582 PQATQPRPPARAQATQGGREGQARTLGPAAP 612 P A P P A+ G + P AP Sbjct: 317 PMAPVPPGPPMARVPPGPPMARVPPGPPMAP 347 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 57.8 bits (138), Expect = 5e-08 Identities = 62/205 (30%), Positives = 71/205 (34%), Gaps = 21/205 (10%) Query: 449 PTEAAPPRSGPQSPAPAAPAQPGATLAPPTP---PRPRDGGTPRHSRALSWAARAARPLP 505 P + P P P P G PP P P P GG P + A + P P Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGP 277 Query: 506 LFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPA--PRAP--WPPFPGVF-----LH 556 + PPP P V P P V+ P P AP P AP PP PGV +H Sbjct: 278 ---PQLPPPAPGVHPPAPVVH----PPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVH 330 Query: 557 PRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDS 616 P P P V AP P G P P P + G QA + PAAP V Sbjct: 331 P-PAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPS-AGVHPQAPGVHPAAPAVHP 388 Query: 617 NLSSEARPVTSFLSLSQVSGPQLPG 641 P + PQ PG Sbjct: 389 QAPGVHPPAPGMHPQAPGVHPQPPG 413 Score = 52.4 bits (124), Expect = 2e-06 Identities = 61/186 (32%), Positives = 66/186 (35%), Gaps = 25/186 (13%) Query: 443 LLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAAR 502 L +SL P PP P P P P PP P P G P A+ Sbjct: 247 LPESLPPP---PPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHP 303 Query: 503 PLPLFLGRAP---PPRPAVEQP-----PPKVYVTRVRPGQRASPRAPAPRAPW--PPFPG 552 P P AP PP P V P PP V PG P AP PP PG Sbjct: 304 PAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPG 363 Query: 553 VFLHPRPLPRVQLRAP---PRPPRPHGRRTGGPQATQPRPPARAQATQG-GREGQARTLG 608 V HP P V +AP P P H PQA PPA Q G Q + Sbjct: 364 V--HPPPSAGVHPQAPGVHPAAPAVH------PQAPGVHPPAPGMHPQAPGVHPQPPGVH 415 Query: 609 PAAPTV 614 P+AP V Sbjct: 416 PSAPGV 421 >gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] Length = 1263 Score = 57.4 bits (137), Expect = 7e-08 Identities = 55/169 (32%), Positives = 57/169 (33%), Gaps = 40/169 (23%) Query: 446 SLEPTEAAPPRSG------PQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAAR 499 S P APP G P PAP P PP PP P GG S Sbjct: 569 SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT 628 Query: 500 AARPLPLFLGRA----PPPRP---------------AVEQPPPKVYVTRVRPGQRASPRA 540 A P P G A PPP P A+ PPP PG S R Sbjct: 629 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL-------PG---SARI 678 Query: 541 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRP 589 P P P P G+ P PLP PP PP P GGP P P Sbjct: 679 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP-----GGPGIPPPPP 722 Score = 46.2 bits (108), Expect = 2e-04 Identities = 41/119 (34%), Positives = 46/119 (38%), Gaps = 19/119 (15%) Query: 454 PPRSGPQSPAPAAPAQPG-ATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRA- 511 PP G P P PG A + PP PP P + G P L P P G Sbjct: 670 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI 729 Query: 512 PPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL--PRVQLRAP 568 PPP P + PPP + V P AP PF L P+ L P VQLR P Sbjct: 730 PPPPPGMGMPPPPPFGFGV------------PAAPVLPFG---LTPKKLYKPEVQLRRP 773 Score = 45.4 bits (106), Expect = 3e-04 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 21/120 (17%) Query: 454 PPRSGPQSPAPAAPAQ-PGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAP 512 PP P+ +P+ PG T PP PP P P L +A P P G A Sbjct: 644 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 703 Query: 513 PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPP 572 P P PPP PG P P P PPFPG P P P + + PP PP Sbjct: 704 MPPP----PPP-------LPG---GPGIPPP----PPFPGGPGIPPPPPGMGM--PPPPP 743 Score = 40.8 bits (94), Expect = 0.007 Identities = 45/149 (30%), Positives = 51/149 (34%), Gaps = 31/149 (20%) Query: 467 PAQPGATLAPPTPPRPRDGGT---PRHSRALSWAARAARPLPLFLGRAPPPRP---AVEQ 520 P+ P PP PP P D GT P + S P P PPP P + Sbjct: 565 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP----PPPPPLPGGVCISS 620 Query: 521 PPPKVYVTRVRPGQRASPRAPAPRAPWPPFP-GVFL-------------HPRPLPRVQLR 566 PP T + P S A P P PP P GV + P PLP Sbjct: 621 PPSLPGGTAISPPPPLSGDATIP--PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 678 Query: 567 APPRPPRPHGRRTGGPQATQPRPPARAQA 595 PP PP P G P PP +A Sbjct: 679 PPPPPPLP-----GSAGIPPPPPPLPGEA 702 >gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] Length = 1272 Score = 57.4 bits (137), Expect = 7e-08 Identities = 55/169 (32%), Positives = 57/169 (33%), Gaps = 40/169 (23%) Query: 446 SLEPTEAAPPRSG------PQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAAR 499 S P APP G P PAP P PP PP P GG S Sbjct: 578 SRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPPPPPPPLPGGVCISSPPSLPGGT 637 Query: 500 AARPLPLFLGRA----PPPRP---------------AVEQPPPKVYVTRVRPGQRASPRA 540 A P P G A PPP P A+ PPP PG S R Sbjct: 638 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPL-------PG---SARI 687 Query: 541 PAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRP 589 P P P P G+ P PLP PP PP P GGP P P Sbjct: 688 PPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLP-----GGPGIPPPPP 731 Score = 46.2 bits (108), Expect = 2e-04 Identities = 41/119 (34%), Positives = 46/119 (38%), Gaps = 19/119 (15%) Query: 454 PPRSGPQSPAPAAPAQPG-ATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRA- 511 PP G P P PG A + PP PP P + G P L P P G Sbjct: 679 PPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPPPFPGGPGI 738 Query: 512 PPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPL--PRVQLRAP 568 PPP P + PPP + V P AP PF L P+ L P VQLR P Sbjct: 739 PPPPPGMGMPPPPPFGFGV------------PAAPVLPFG---LTPKKLYKPEVQLRRP 782 Score = 45.4 bits (106), Expect = 3e-04 Identities = 41/120 (34%), Positives = 47/120 (39%), Gaps = 21/120 (17%) Query: 454 PPRSGPQSPAPAAPAQ-PGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAP 512 PP P+ +P+ PG T PP PP P P L +A P P G A Sbjct: 653 PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPLPGSAGIPPPPPPLPGEAG 712 Query: 513 PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPP 572 P P PPP PG P P P PPFPG P P P + + PP PP Sbjct: 713 MPPP----PPP-------LPG---GPGIPPP----PPFPGGPGIPPPPPGMGM--PPPPP 752 Score = 40.8 bits (94), Expect = 0.007 Identities = 45/149 (30%), Positives = 51/149 (34%), Gaps = 31/149 (20%) Query: 467 PAQPGATLAPPTPPRPRDGGT---PRHSRALSWAARAARPLPLFLGRAPPPRP---AVEQ 520 P+ P PP PP P D GT P + S P P PPP P + Sbjct: 574 PSVPSRAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPPPPP----PPPPPLPGGVCISS 629 Query: 521 PPPKVYVTRVRPGQRASPRAPAPRAPWPPFP-GVFL-------------HPRPLPRVQLR 566 PP T + P S A P P PP P GV + P PLP Sbjct: 630 PPSLPGGTAISPPPPLSGDATIP--PPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARI 687 Query: 567 APPRPPRPHGRRTGGPQATQPRPPARAQA 595 PP PP P G P PP +A Sbjct: 688 PPPPPPLP-----GSAGIPPPPPPLPGEA 711 >gi|117306167 proline-rich protein BstNI subfamily 3 precursor [Homo sapiens] Length = 309 Score = 57.4 bits (137), Expect = 7e-08 Identities = 49/163 (30%), Positives = 60/163 (36%), Gaps = 19/163 (11%) Query: 451 EAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGR 510 E PP+ G QS P P +PG PP + G P H P + Sbjct: 142 EGPPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPHPGK----PEGPPPQGGNQSQ 195 Query: 511 APPPRPAVEQPPPKVYVTRV-----RPGQRASPRAPAPRAPW--PPFPGVFLHPRPLPRV 563 PPPRP + PP + RPG+ P + P PP PG P P Sbjct: 196 GPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKPQGPPPHPGKPQGPPPQEGN 255 Query: 564 QLRAPPRPPRPHGRRTGGPQATQPRPPARAQ------ATQGGR 600 + + PP P RP G G QP PP + QGGR Sbjct: 256 KPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQGPPPPPQGGR 298 Score = 51.2 bits (121), Expect = 5e-06 Identities = 56/191 (29%), Positives = 75/191 (39%), Gaps = 31/191 (16%) Query: 451 EAAPPRSGPQSPAPAAPAQPGATLAPPT---------PPRPR--DGGTPRH-SRALSWAA 498 E PP+ G QS P P +PG PP PPRP +G P+ +++ Sbjct: 58 EGRPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGQPPQGGNQSQGPPP 115 Query: 499 RAARPL-PLFLG----RAPPPRPAVEQPPPKVYVTRVR--PGQRASPRAPAPRAPW---- 547 R +P P G + PPPRP + PP + + P + P P P+ Sbjct: 116 RPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 175 Query: 548 -PPFPGVFLHPRPLPRVQLRAPP-RPPRPHGRRTGGPQATQPRPP----ARAQATQGGRE 601 PP PG P P Q + PP RP +P G G +Q PP +QGG + Sbjct: 176 PPPHPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNK 235 Query: 602 GQARTLGPAAP 612 Q P P Sbjct: 236 PQGPPPHPGKP 246 Score = 46.2 bits (108), Expect = 2e-04 Identities = 43/138 (31%), Positives = 50/138 (36%), Gaps = 20/138 (14%) Query: 451 EAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGR 510 E PP+ G QS P P +PG PP + G P P + Sbjct: 184 EGPPPQGGNQSQGP--PPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPSQGGNKP----Q 237 Query: 511 APPPRPAVEQPPPKVYVTRVRPGQRASP-RAPAPRAPW--PPFPGVFLHPRPLPRVQLRA 567 PPP P Q PP P + P R P P P PP G P P P + + Sbjct: 238 GPPPHPGKPQGPP--------PQEGNKPQRPPPPGRPQGPPPPGGNPQQPLPPPAGKPQG 289 Query: 568 PPRPP---RPHGRRTGGP 582 PP PP RPH G P Sbjct: 290 PPPPPQGGRPHRPPQGQP 307 Score = 43.9 bits (102), Expect = 8e-04 Identities = 49/170 (28%), Positives = 57/170 (33%), Gaps = 38/170 (22%) Query: 459 PQSPAPAAPAQPGATLAPPTPP--RPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPRP 516 P+ P QP T PP P RP GG + PPPRP Sbjct: 36 PEGRRPQGGNQPQRTPPPPGKPEGRPPQGGNQ--------------------SQGPPPRP 75 Query: 517 AV-EQPPPKVYVTRVRPGQRASPRAPAPRAPW--------PPFPGVFLHPRPLPRVQLRA 567 E PPP+ P R P P + P PP PG P P Q + Sbjct: 76 GKPEGPPPQGGNQSQGPPPR--PGKPEGQPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQG 133 Query: 568 PP-RPPRPHGRRTGGPQATQPRPP----ARAQATQGGREGQARTLGPAAP 612 PP RP +P G G +Q PP QGG + Q P P Sbjct: 134 PPPRPGKPEGPPPQGGNQSQGPPPRPGKPEGPPPQGGNQSQGPPPHPGKP 183 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 57.0 bits (136), Expect = 9e-08 Identities = 64/202 (31%), Positives = 70/202 (34%), Gaps = 54/202 (26%) Query: 446 SLEPTEAAPPRSGPQSPAPAAPAQPG--ATLAPPTPPRPRDGGTP--------------- 488 S P AA + PAPA PA+P A LA P P G P Sbjct: 136 SCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAA 195 Query: 489 ---RHSRALSWAARAARPLPLFLGRAPP-----PRPA----VEQPPPKVYVTRVRPGQRA 536 S AL + AA P + P P+PA V Q PP V Sbjct: 196 QTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV----------G 245 Query: 537 SPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPP-------RPHGRRTGGPQATQPRP 589 + PAP AP PP P P APP PP RP G G P A P Sbjct: 246 AAAPPAPAAPSPP-------AAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAA-PAV 297 Query: 590 PARAQATQGGREGQARTLGPAA 611 P A A GG G A PAA Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAA 319 Score = 55.1 bits (131), Expect = 3e-07 Identities = 63/220 (28%), Positives = 76/220 (34%), Gaps = 34/220 (15%) Query: 448 EPTEAAPPR-SGPQS------PAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARA 500 EP A P + +GP + P P PG P P P T S AL + A Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210 Query: 501 ARPLPLFLGRAPP-----PRPA-----VEQPPPKVYVTRVRPGQRASPRAPAPRAPW--- 547 A P + P P+PA ++ PP P + P APAP AP Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270 Query: 548 ---PPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQA 604 PP P P P A P P P + GG P P A GG G + Sbjct: 271 PPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAA----GGPAGVS 326 Query: 605 RTLGP----AAPTVDSNLSSEARPVTSFLSLSQ---VSGP 637 GP AAP S R V + +Q SGP Sbjct: 327 GQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGP 366 Score = 41.6 bits (96), Expect = 0.004 Identities = 47/160 (29%), Positives = 55/160 (34%), Gaps = 23/160 (14%) Query: 452 AAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRA 511 A PP + P P PAA G+ A P P P GG S A AA P P +A Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPA-PAAGGPAGVSGQPGPGAAAAAPAPGV--KA 344 Query: 512 PPPRPAVEQPPPKVYVTRVR-PGQRASPRA---------PAPRAPWPPFPGVFLHPRPLP 561 P+ V+ PP P A+ P+P A PP PG P LP Sbjct: 345 ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT---PTGLP 401 Query: 562 R-------VQLRAPPRPPRPHGRRTGGPQATQPRPPARAQ 594 + L P R T P PR P Q Sbjct: 402 KGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQ 441 Score = 40.0 bits (92), Expect = 0.011 Identities = 55/193 (28%), Positives = 66/193 (34%), Gaps = 33/193 (17%) Query: 457 SGPQSPAPAAPAQ--PGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPP 514 +G PAAPA+ PGA PP R R GG RP G P Sbjct: 68 AGAAGAGPAAPAEGAPGAAPEPPPAGRARPGG-----------GGPQRP-----GPPSPR 111 Query: 515 RPAVEQ-PPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPR 573 RP V P P R P A AP P A V P P P A P P Sbjct: 112 RPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA-----AAVAAGPEPAPAGP--AKPAGPA 164 Query: 574 PHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFL---- 629 R G P P + G A+TL +A ++S+ A P S + Sbjct: 165 ALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSH--HAAAPAVSLVNNGP 222 Query: 630 -SLSQVSGPQLPG 641 +L + P PG Sbjct: 223 AALLPLPKPAAPG 235 Score = 38.1 bits (87), Expect = 0.043 Identities = 44/176 (25%), Positives = 55/176 (31%), Gaps = 21/176 (11%) Query: 513 PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRV-------QL 565 P P V V G A P AP PG P P R Q Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104 Query: 566 RAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPV 625 PP P RP P A + RPP A A + + + A P Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164 Query: 626 TSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASE---------DSEEAAGPAL 672 +L+ +GP PG G G G P A++ +S AA PA+ Sbjct: 165 ----ALAARAGPG-PGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAV 215 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 57.0 bits (136), Expect = 9e-08 Identities = 64/215 (29%), Positives = 83/215 (38%), Gaps = 41/215 (19%) Query: 453 APPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARP--LPLFLGR 510 +PP GP + P APP PP P P A + +A +P PL L Sbjct: 202 SPP--GPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP 259 Query: 511 APPPRPAVEQPPPKVYVTRVRPGQRASPRAPA-----PRAPWPPF-------PGVFLHPR 558 PPP P + PP Y PG +A P +PA P AP PP P L Sbjct: 260 IPPPLPLL---PPCGY-----PGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAP 311 Query: 559 PLPRVQLRA---PPRPPRPHG----RRTGGPQA--TQPRPPARAQATQGGREGQARTLG- 608 PLP V + PP PP+ + G QA P PP Q R G+ G Sbjct: 312 PLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGG 371 Query: 609 -------PAAPTVDSNLSSEARPVTSFLSLSQVSG 636 P A + + LSS+++ T++ Q G Sbjct: 372 KLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGG 406 Score = 44.3 bits (103), Expect = 6e-04 Identities = 44/164 (26%), Positives = 60/164 (36%), Gaps = 46/164 (28%) Query: 447 LEPTEAAPPRSGPQSPAPAAPAQPGATLAP----PTPPRPRDGGTPRHSRALSWAARAAR 502 L+ A+P + + PAP P P A+ +P P PP P + + Sbjct: 275 LKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSS------------SET 322 Query: 503 PLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPR 562 P PL PP P+ + PP K G +A P PAP P P Sbjct: 323 PPPL-----PPKSPSFQAPPQKA-------GAQALPAPPAP-------------PGSQPF 357 Query: 563 VQLRAPPRPPRPHGRRTGGPQATQPRPPARAQATQGGREGQART 606 +Q + RP GG P PPAR+ T+ + Q T Sbjct: 358 LQKKRHGRP-----GAGGGKLNPPPAPPARSPTTELSSKSQQAT 396 Score = 41.6 bits (96), Expect = 0.004 Identities = 45/145 (31%), Positives = 51/145 (35%), Gaps = 40/145 (27%) Query: 458 GPQSPAPAAPAQPGATLAPPT--PPRPRDGGTPRHSRALSWAARAARPLPLFLGRAPPPR 515 GP S AP+ P P T++ P P PR G T A R PPR Sbjct: 125 GPGSRAPS-PRLPNKTISGPLIPPASPRLGNTSEAHGA---------------ARTAPPR 168 Query: 516 PAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPG-------VFLHPRPLPRVQLR-- 566 P V PPP +P P P P PP P + P PL + L Sbjct: 169 PNVPAPPP------------PTPPPPPPPLP-PPLPSSSPIKTPLVSPPGPLTKGNLPVV 215 Query: 567 APPRPPRPHGRRTGGPQATQPRPPA 591 APP P P P P PPA Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPA 240 Score = 37.0 bits (84), Expect = 0.097 Identities = 41/152 (26%), Positives = 53/152 (34%), Gaps = 22/152 (14%) Query: 483 RDGGTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPA 542 ++GG ++R S LF G P RPA ++ V + GQ RAP+ Sbjct: 81 KEGGGSANTRGASTPPTLG---DLFAGGFPVLRPAGQRD-----VAGGKTGQGPGSRAPS 132 Query: 543 PRAPWPPFPGVFLHPRPLPRV---------QLRAPPRPPRPHGRRTGGPQATQPRPPARA 593 PR P G + P PR+ APPRP P P P PP Sbjct: 133 PRLPNKTISGPLIPPAS-PRLGNTSEAHGAARTAPPRPNVP----APPPPTPPPPPPPLP 187 Query: 594 QATQGGREGQARTLGPAAPTVDSNLSSEARPV 625 + + P P NL A PV Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPV 219 Score = 32.3 bits (72), Expect = 2.4 Identities = 24/83 (28%), Positives = 30/83 (36%), Gaps = 16/83 (19%) Query: 444 LDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTP-----RHSRALSWAA 498 L + + PP P+SP+ AP Q A P PP P G P RH R + Sbjct: 313 LPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAP-PGSQPFLQKKRHGRPGAGGG 371 Query: 499 RAARPLPLFLGRAPPPRPAVEQP 521 + PPP P P Sbjct: 372 KL----------NPPPAPPARSP 384 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 57.0 bits (136), Expect = 9e-08 Identities = 70/249 (28%), Positives = 90/249 (36%), Gaps = 45/249 (18%) Query: 410 KEEGDEDEEDEVQRRAFLFLNPDDFLDDEDEGEL------LDSLE-------PTEAAPPR 456 +EE +E+EE+ V + P+DF D +E L +DSL TEA P Sbjct: 1142 EEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPE 1201 Query: 457 SGP----QSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPLFLGRAP 512 P + P P +P + PP P G S ARP PL RAP Sbjct: 1202 ERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARP-PLSPERAP 1260 Query: 513 PPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPP 572 VE PP + ++ P P PR P PP P P P PP Sbjct: 1261 EHDLEVEPEPPMMLPLPLQ------PPLPPPRPPRPPSP-----PPEPETTDASHPSVPP 1309 Query: 573 RPHGRRTGGPQATQPRPPARAQATQGGREGQARTLGPAAPTVDSNLSSEARPVTSFLSLS 632 P + PP + Q+ PA P + LS +S LSL Sbjct: 1310 EP---------LAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGG----SSGLSL- 1355 Query: 633 QVSGPQLPG 641 S PQ+PG Sbjct: 1356 --SSPQVPG 1362 Score = 42.0 bits (97), Expect = 0.003 Identities = 52/174 (29%), Positives = 59/174 (33%), Gaps = 33/174 (18%) Query: 435 LDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATL-----APPTPPRPRDG---- 485 L D DE E LD L PP GP PA L PT + +G Sbjct: 577 LPDSDEDEELD-LGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSS 635 Query: 486 ------GTPRHSRALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPR 539 A +A +P+ + G A P+V P T P P Sbjct: 636 GEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP------TLPLPPPPGFPP 689 Query: 540 APAPRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRRTGGPQATQPRPPARA 593 P P P PP PG F P PLP PP PP P P T P PP A Sbjct: 690 LPPPPPPPPPQPG-FPMPPPLP-----PPPPPPPP-----AHPAVTVPPPPLPA 732 Score = 40.0 bits (92), Expect = 0.011 Identities = 36/109 (33%), Positives = 39/109 (35%), Gaps = 37/109 (33%) Query: 447 LEPTEAAPPRSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHSRALSWAARAARPLPL 506 L P PP P P P QPG + PP PP P P P Sbjct: 681 LPPPPGFPPLPPP---PPPPPPQPGFPMPPPLPPPP--------------------PPP- 716 Query: 507 FLGRAPPPRPAVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPF-PGVF 554 PP PAV PPP + PG P P P PPF PG+F Sbjct: 717 -----PPAHPAVTVPPPPL---PAPPGVPPPPILP----PLPPFPPGLF 753 Score = 37.7 bits (86), Expect = 0.057 Identities = 50/169 (29%), Positives = 60/169 (35%), Gaps = 33/169 (19%) Query: 456 RSGPQSPAPAAPAQPGATLAPPTPPRPRDGGTPRHS--RALSWAARAARP-LPLFLGRAP 512 R+ ++P P P P A LA PP R G PR S LS RP LGR Sbjct: 1448 RAQARAPTPLPPLLP-APLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGREL 1506 Query: 513 PPRPAVEQPP--PKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHPRPLPRVQLRAPPR 570 P Q P P + R + PAP P PP P PP Sbjct: 1507 LLLPGQPQTPVFPSTHDPRTVTLDFRNAGIPAPPPPLPPQP----------------PPP 1550 Query: 571 PPRPHGRRTGGP----------QATQPRPPARAQATQGGREGQARTLGP 609 PP P T P +A P P R + T+ E A++ GP Sbjct: 1551 PPPPPVEPTKLPFKELDNQWPSEAIPPGPRGRDEVTEEYME-LAKSRGP 1598 Score = 36.2 bits (82), Expect = 0.17 Identities = 63/244 (25%), Positives = 86/244 (35%), Gaps = 48/244 (19%) Query: 431 PDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLA--PPTPPRPRDGGTP 488 P+ L+ E E ++ L PP P+ P+P P +P T A P PP P P Sbjct: 1260 PEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSP--PPEPETTDASHPSVPPEPLAEDHP 1317 Query: 489 RHSRALSWA---ARAARPLPLFLGRAPP---PRPAVEQPPPKVYVTRVRPGQRASPRAPA 542 H+ L + +++ +P G PP + P+V PG S AP+ Sbjct: 1318 PHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQV------PGSPFSYPAPS 1371 Query: 543 --------PRAPWPPFPGVFLHPRPLPRVQLRAPPRPPRPHGRR--TGGPQATQ------ 586 PR P F P + L P P P GRR GP A+ Sbjct: 1372 PSLSSGGLPRTPGRDFSFTPTFSEPSGPLLL---PVCPLPTGRRDERSGPLASPVLLETG 1428 Query: 587 -----PRPPARAQATQGGREGQARTLGPAAPTVDSNLSS--------EARPVTSFLSLSQ 633 P P A QAR P P + + L+S RP S S+ Sbjct: 1429 LPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPPMKRKPGRPRRSPPSMLS 1488 Query: 634 VSGP 637 + GP Sbjct: 1489 LDGP 1492 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.137 0.425 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 50,068,891 Number of Sequences: 37866 Number of extensions: 3161006 Number of successful extensions: 34460 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 235 Number of HSP's successfully gapped in prelim test: 1689 Number of HSP's that attempted gapping in prelim test: 19899 Number of HSP's gapped (non-prelim): 10014 length of query: 1039 length of database: 18,247,518 effective HSP length: 112 effective length of query: 927 effective length of database: 14,006,526 effective search space: 12984049602 effective search space used: 12984049602 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.