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Search of human proteins with 40548408
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40548408 p30 DBC protein [Homo sapiens]
(923 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40548408 p30 DBC protein [Homo sapiens] 1848 0.0
gi|24432106 p30 DBC protein [Homo sapiens] 1848 0.0
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 309 7e-84
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 53 1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 49 3e-05
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 49 3e-05
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 49 3e-05
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 49 3e-05
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 49 3e-05
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 49 3e-05
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 49 3e-05
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 49 3e-05
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 47 8e-05
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 45 3e-04
gi|149999615 variable charge, X-linked 3B [Homo sapiens] 45 4e-04
gi|157738619 smoothelin-like 1 [Homo sapiens] 45 4e-04
gi|221219020 NYD-SP11 protein [Homo sapiens] 44 5e-04
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 44 7e-04
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 44 7e-04
gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 44 0.001
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 43 0.001
gi|16262452 cingulin [Homo sapiens] 42 0.002
gi|4506411 Ran GTPase activating protein 1 [Homo sapiens] 42 0.002
gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Hom... 42 0.003
gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Hom... 42 0.003
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 42 0.003
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 42 0.003
gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo sap... 42 0.003
gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo sap... 42 0.003
gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo sap... 42 0.003
>gi|40548408 p30 DBC protein [Homo sapiens]
Length = 923
Score = 1848 bits (4787), Expect = 0.0
Identities = 923/923 (100%), Positives = 923/923 (100%)
Query: 1 MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG 60
MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG
Sbjct: 1 MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG 60
Query: 61 IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP 120
IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP
Sbjct: 61 IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP 120
Query: 121 LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR 180
LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR
Sbjct: 121 LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR 180
Query: 181 FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF 240
FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF
Sbjct: 181 FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF 240
Query: 241 LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA 300
LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA
Sbjct: 241 LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA 300
Query: 301 DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV 360
DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV
Sbjct: 301 DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV 360
Query: 361 GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ 420
GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ
Sbjct: 361 GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ 420
Query: 421 TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR 480
TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR
Sbjct: 421 TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR 480
Query: 481 NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL 540
NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL
Sbjct: 481 NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL 540
Query: 541 AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD 600
AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD
Sbjct: 541 AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD 600
Query: 601 EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE 660
EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE
Sbjct: 601 EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE 660
Query: 661 EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL 720
EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL
Sbjct: 661 EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL 720
Query: 721 HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL 780
HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL
Sbjct: 721 HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL 780
Query: 781 DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL 840
DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL
Sbjct: 781 DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL 840
Query: 841 EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ 900
EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ
Sbjct: 841 EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ 900
Query: 901 LEIQRVVEKADSWVEKEEPAPSN 923
LEIQRVVEKADSWVEKEEPAPSN
Sbjct: 901 LEIQRVVEKADSWVEKEEPAPSN 923
>gi|24432106 p30 DBC protein [Homo sapiens]
Length = 923
Score = 1848 bits (4787), Expect = 0.0
Identities = 923/923 (100%), Positives = 923/923 (100%)
Query: 1 MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG 60
MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG
Sbjct: 1 MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTG 60
Query: 61 IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP 120
IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP
Sbjct: 61 IVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQP 120
Query: 121 LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR 180
LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR
Sbjct: 121 LLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNR 180
Query: 181 FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF 240
FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF
Sbjct: 181 FPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDF 240
Query: 241 LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA 300
LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA
Sbjct: 241 LELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITA 300
Query: 301 DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV 360
DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV
Sbjct: 301 DSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLV 360
Query: 361 GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ 420
GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ
Sbjct: 361 GGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQ 420
Query: 421 TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR 480
TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR
Sbjct: 421 TVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRR 480
Query: 481 NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL 540
NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL
Sbjct: 481 NAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVL 540
Query: 541 AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD 600
AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD
Sbjct: 541 AELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD 600
Query: 601 EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE 660
EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE
Sbjct: 601 EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE 660
Query: 661 EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL 720
EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL
Sbjct: 661 EEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYL 720
Query: 721 HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL 780
HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL
Sbjct: 721 HRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNL 780
Query: 781 DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL 840
DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL
Sbjct: 781 DLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKL 840
Query: 841 EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ 900
EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ
Sbjct: 841 EESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQ 900
Query: 901 LEIQRVVEKADSWVEKEEPAPSN 923
LEIQRVVEKADSWVEKEEPAPSN
Sbjct: 901 LEIQRVVEKADSWVEKEEPAPSN 923
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 309 bits (792), Expect = 7e-84
Identities = 185/473 (39%), Positives = 258/473 (54%), Gaps = 59/473 (12%)
Query: 53 EKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVK 112
+KQRVFTG+VT LHD FG VDE+VFFQLS VKG+ PQ+G++VLV+A YNP WNA +
Sbjct: 145 QKQRVFTGVVTKLHDTFGFVDEDVFFQLSAVKGKTPQVGDRVLVEATYNPNMPFKWNAQR 204
Query: 113 VQTLSN------QPLLKSPAPPLLHVA--------ALGQKQGILGA-------------Q 145
+QTL N QPLLK+P L +A Q Q +L A Q
Sbjct: 205 IQTLPNQNQSQTQPLLKTPPAVLQPIAPQTTFGVQTQPQPQSLLQAQISAASITPLLQTQ 264
Query: 146 PQ-LIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRK 204
PQ L+ QP + L + Q L +RF R G R DD ++ +
Sbjct: 265 PQPLLQQPQQKAGLLQPPVRIVSQPQPARRLDPPSRFSGRNDRGDQVPNRKDDRSRERER 324
Query: 205 QRAGGEPWGAKK-------PRHD-----------LPPYRVHLTPYTVDSPICDFLELQRR 246
+R ++ PR + +P Y V + +++D P CD +EL+RR
Sbjct: 325 ERRRSRERSPQRKRSRERSPRRERERSPRRVRRVVPRYTVQFSKFSLDCPSCDMMELRRR 384
Query: 247 YRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQV-SSEKEAAPDAGAEPITADSDPA 305
Y++L +PSDF +W+ AFPLS+PF L + V E E+ A D+D
Sbjct: 385 YQNLYIPSDFFDAQFTWVDAFPLSRPFQLGNYCNFYVMHREVESLEKNMAILDPPDADHL 444
Query: 306 YSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRK-EEEAVLVGGEW 364
YS+KV+L++SP +E+LY +D E R+ +HP + +KFL+G K ++EA+ +GG W
Sbjct: 445 YSAKVMLMASPSMEDLYHKSCALAEDPQELRDGFQHPARLVKFLVGMKGKDEAMAIGGHW 504
Query: 365 SPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGP-------PR 417
SPSLDG DP+ DP VL++TAIRC +A TGIDLS CT+W+RFAE +Y +P P
Sbjct: 505 SPSLDGPDPEKDPSVLIKTAIRCCKALTGIDLSVCTQWYRFAEIRYHRPEETHKGRTVPA 564
Query: 418 RLQTVVVYLPDVWTIMPTLEEWEALC----QQKAAEAAPPTQEAQGETEPTEQ 466
++TVV++ PDVW +PT EWE L QQ + +EA GE + E+
Sbjct: 565 HVETVVLFFPDVWHCLPTRSEWETLSRGYKQQLVEKLQGERKEADGEQDEEEK 617
Score = 192 bits (487), Expect = 2e-48
Identities = 146/473 (30%), Positives = 234/473 (49%), Gaps = 35/473 (7%)
Query: 455 QEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPP-PLEPAVIARP 513
+E Q E E +E+ D E S + E E Q+E + E P EPA+I P
Sbjct: 676 KEEQKELEKSEKEED--EDDDRKSEDDKEEEERKRQEEIERQRRERRYILPDEPAIIVHP 733
Query: 514 G---------CVNLSLHGIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSL 563
C +SL +++ R + SFEV + AELF EMLQRDFG R+YK LLSL
Sbjct: 734 NWAAKSGKFDCSIMSLSVLLDYRLEDNKEHSFEVSLFAELFNEMLQRDFGVRIYKSLLSL 793
Query: 564 PEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPL----KEDG 619
PEK + EK++ +K++ K+++ +++ EPK + + G + + KED
Sbjct: 794 PEK---EDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDK 850
Query: 620 LLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASN 679
EE+ + E E A D E DD +EE + + ++
Sbjct: 851 RKDDSKDDDETEEDNNQDEYDPMEAEEAEDEE-----DDRDEEEMTKRDDKRDINRYCKE 905
Query: 680 QSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAE 739
+ +D KE + D L+AFV+FD + CGYL +DLE IL TLG+ LS
Sbjct: 906 RPS------KDKEKEKTQMITINRDLLMAFVYFDQSHCGYLLEKDLEEILYTLGLHLSRA 959
Query: 740 QAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPE---EVLFGNLDLLPPPGKSTKPGAAP 796
Q K+L+++VV + C YR L + ++ + E E + GN LLP P +
Sbjct: 960 QVKKLLNKVVLRESCFYRKLTDTSKDEENHEESESLQEDMLGNRLLLPTPTVKQESKDVE 1019
Query: 797 TEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKT 856
E+ L+ +NG++++VGSLLQ+ E+ + R +E K+ LE K +E E +NK+
Sbjct: 1020 -ENVGLIVYNGAMVDVGSLLQKLEKSEKVRAEVEQKLQLLEEKTDEDEKTILNLENSNKS 1078
Query: 857 LAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEK 909
L+ E++E++ L++ +E + +E Q + + + R L+ + EI V++K
Sbjct: 1079 LSGELREVKKDLSQLQENLKISENMNLQFENQMNKTIRNLSTVMDEIHTVLKK 1131
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 53.1 bits (126), Expect = 1e-06
Identities = 68/246 (27%), Positives = 104/246 (42%), Gaps = 23/246 (9%)
Query: 446 KAAEAAPPTQEAQGETEPTE---QAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPP 502
+A EA QEA+GE +P +AP+A E A + ETPEA + + +++ EAP
Sbjct: 1852 EAPEAEGDAQEAEGEAQPESEDVEAPEA-EGEAQPESEDVETPEAEWEVQPESEGAEAPE 1910
Query: 503 PPLEPAVIARPGCVNL-SLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLL 561
E A+P ++ +L ED E A+ E Q G + +
Sbjct: 1911 AEKE----AQPETESVEALETEGEDEPESEGAE------AQEAEEAAQEAEGQTQPESEV 1960
Query: 562 SLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKD----EAQNEGPATESEAPLKE 617
++ +PE E+ E E + + E E +D EA+ E E EA +
Sbjct: 1961 IESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPES 2020
Query: 618 DGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPEL-LLLRDDGEEEFAGAKLEDSEVRSV 676
DG+ +P S GEE ++ GE + E PE + + EEE A+ E E
Sbjct: 2021 DGVEAQP-KSEGEEAQEVEGETQK--TEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGE 2077
Query: 677 ASNQSE 682
A +SE
Sbjct: 2078 AHPESE 2083
Score = 44.7 bits (104), Expect = 4e-04
Identities = 52/239 (21%), Positives = 92/239 (38%), Gaps = 31/239 (12%)
Query: 438 EWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDL 497
EWE + + AEA +EAQ ETE E E ++ A+ E Q+
Sbjct: 1896 EWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQ 1955
Query: 498 PEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVY 557
PE+ ++E + +E E + L +E+ ++
Sbjct: 1956 PESE---------------------VIESQEAEEEAQPESEDVEALEVEVETQEAEGE-- 1992
Query: 558 KMLLSLPE-KVVSPPEPEKE-EAAKEEATKEEEAIKEEVVKEPKD--EAQNEGPATESEA 613
+ PE + V PE E E + A+EEA E + ++ + E ++ E + E TE +A
Sbjct: 1993 ----AQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDA 2048
Query: 614 PLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSE 672
+ DG+ +E E EA + + D + + + E G + ++E
Sbjct: 2049 QPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAE 2107
Score = 40.8 bits (94), Expect = 0.006
Identities = 56/232 (24%), Positives = 94/232 (40%), Gaps = 37/232 (15%)
Query: 437 EEWEALCQQKAAEAAPPT-----QEAQGETEPTEQAPDALEQAADTSRRNA-ETPEATTQ 490
+E E Q+ EA P + QEA+GE +P + +A E + + E PE +
Sbjct: 2065 QEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 491 QETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPK----ERISFEVMVLAELF-L 545
+ +++ EAP E A+P + + +P+ E E EL +
Sbjct: 2125 AQPESEGIEAPEAEGE----AQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGV 2180
Query: 546 EMLQRDFGYRVYKMLLSLPE-KVVSPPEPEKEEA--AKEEATKEEEAIKE---EVVKEPK 599
E + + + + PE + + PE E EA A+EEA E E ++ E +P+
Sbjct: 2181 EAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPE 2240
Query: 600 DEAQNEGP----------------ATESEAPLKEDGLLPKPLSSGGEEEEKP 635
E + +G A+ES +P+ ED P P G ++P
Sbjct: 2241 SEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRP 2292
Score = 33.9 bits (76), Expect = 0.72
Identities = 41/140 (29%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 573 PEKEEAAKEEATKEEEAIKEEVVKEPKDEAQN-----EGPATESEA-PLKEDGLLP---- 622
PE E A+ E+ E E +E + EAQ E P E EA P ED P
Sbjct: 1838 PEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEW 1897
Query: 623 --KPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGA-KLEDSEVRSVASN 679
+P S G E E + E AL+ E D+ E E A A + E++ +
Sbjct: 1898 EVQPESEGAEAPEAEKEAQPETESVEALETE---GEDEPESEGAEAQEAEEAAQEAEGQT 1954
Query: 680 QSEMEFSSLQDMPKELDPSA 699
Q E E Q+ +E P +
Sbjct: 1955 QPESEVIESQEAEEEAQPES 1974
Score = 31.6 bits (70), Expect = 3.6
Identities = 42/153 (27%), Positives = 57/153 (37%), Gaps = 19/153 (12%)
Query: 563 LPEKVVSPPEPEKEEAAKEEAT-------------KEEEAIKEEVVKEPKDEAQNEGPAT 609
L E+ V E + EE +EE +EEEA EE+ + + Q EG
Sbjct: 1315 LQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQL 1374
Query: 610 ESEAPLKEDGLLPKPLSSGGEEEEKP-RGEASEDLCEMALDPELLLLRDDG--EEEFAGA 666
E E GL + L G +EE P G A P+ ++D +EE AG
Sbjct: 1375 EEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGR 1434
Query: 667 KLEDSEVRSVASNQSEMEFSSLQDMPKELDPSA 699
+E + E S E DPSA
Sbjct: 1435 ASASAEPCPAEGTEEPTEPPS---HLSETDPSA 1464
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1333 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1392
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1452
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1453 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1505 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1563
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1564 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1619
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1620 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1671
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1672 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1728
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1729 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1787
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1788 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1821
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1438 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1490
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1532
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2561 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2608
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1911 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2085
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2086 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2112
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2220
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2221 --RQRSQVEEELFSVRVQMEEL 2240
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1769 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1824
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1825 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1880
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1937
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1938 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1988
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2042
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2103 EAAQSRRQVEEAER 2116
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1337 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1396
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1397 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1456
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1457 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1508
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1509 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1567
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1568 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1623
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1624 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1675
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1676 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1732
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1733 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1791
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1792 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1825
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1442 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1494
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1495 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1536
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2505 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2564
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2565 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2612
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1915 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1971
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1972 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2031
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2032 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2089
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2090 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2116
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2117 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2177 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2224
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2225 --RQRSQVEEELFSVRVQMEEL 2244
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1653 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1712
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1713 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1772
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1773 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1828
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1829 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1884
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1885 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1941
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1942 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1992
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1993 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2046
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2047 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2106
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2107 EAAQSRRQVEEAER 2120
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1333 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1392
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1393 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1452
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1453 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1504
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1505 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1563
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1564 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1619
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1620 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1671
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1672 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1728
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1729 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1787
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1788 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1821
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1438 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1490
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1491 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1532
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2501 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2560
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2561 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2608
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1911 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1967
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1968 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2027
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2028 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2085
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2086 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2112
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2113 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2220
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2221 --RQRSQVEEELFSVRVQMEEL 2240
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1649 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1708
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1709 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1768
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1769 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1824
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1825 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1880
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1881 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1937
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1938 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1988
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1989 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2042
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2043 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2102
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2103 EAAQSRRQVEEAER 2116
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1301 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1360
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1361 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1420
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1421 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1472
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1473 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1531
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1532 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1587
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1588 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1639
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1640 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1696
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1697 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1755
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1756 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1789
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1406 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1458
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1459 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1500
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2469 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2528
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2529 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2576
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1879 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1935
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1936 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 1995
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 1996 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2053
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2054 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2080
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2081 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2141 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2188
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2189 --RQRSQVEEELFSVRVQMEEL 2208
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1617 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1676
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1677 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1736
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1737 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1792
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1793 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1848
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1849 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1905
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1906 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1956
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1957 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2010
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2011 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2070
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2071 EAAQSRRQVEEAER 2084
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1470 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1529
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1530 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1589
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1590 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1641
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1642 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1700
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1701 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1756
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1757 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1808
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1809 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1865
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1866 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1924
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1925 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1958
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1575 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1627
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1628 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1669
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2638 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2697
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2698 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2745
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 2048 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 2104
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 2105 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2164
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2165 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2222
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2223 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2249
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2250 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2310 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2357
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2358 --RQRSQVEEELFSVRVQMEEL 2377
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1786 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1845
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1846 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1905
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1906 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1961
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1962 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 2017
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 2018 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 2074
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 2075 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 2125
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 2126 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2179
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2180 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2239
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2240 EAAQSRRQVEEAER 2253
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1311 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1370
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1371 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1430
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1431 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1482
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1483 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1541
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1542 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1597
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1598 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1649
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1650 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1706
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1707 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1765
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1766 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1799
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1416 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1468
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1469 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1510
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2479 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2538
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2539 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2586
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1889 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1945
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1946 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2005
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2006 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2063
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2064 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2090
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2091 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2151 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2198
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2199 --RQRSQVEEELFSVRVQMEEL 2218
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1627 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1686
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1687 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1746
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1747 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1802
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1803 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1858
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1859 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1915
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1916 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1966
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1967 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2020
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2021 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2080
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2081 EAAQSRRQVEEAER 2094
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1319 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1378
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1379 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1438
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1439 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1490
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1491 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1549
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1550 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1605
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1606 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1657
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1658 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1714
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1715 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1773
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1774 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1807
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1424 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1476
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1477 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1518
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2487 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2546
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2547 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2594
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1897 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1953
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1954 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2013
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2014 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2071
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2072 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2098
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2099 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2159 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2206
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2207 --RQRSQVEEELFSVRVQMEEL 2226
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1635 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1694
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1695 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1754
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1755 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1810
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1811 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1866
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1867 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1923
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1924 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 1974
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 1975 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2028
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2029 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2088
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2089 EAAQSRRQVEEAER 2102
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 48.5 bits (114), Expect = 3e-05
Identities = 112/514 (21%), Positives = 191/514 (37%), Gaps = 52/514 (10%)
Query: 425 YLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAET 484
Y+ + + +EE E L +Q+ AE E + E Q +A QA + R A+
Sbjct: 1360 YIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKE 1419
Query: 485 ------PEATTQQETDTDLPEAPPPPLEPAVIARPGC---VNLSLHGIVEDRRPKERISF 535
E ++E D + E R + R + RI
Sbjct: 1420 LQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEE 1479
Query: 536 EVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVV 595
E+ V+ L LE +R G + E E+ EA K +A +E E ++ +V
Sbjct: 1480 EIRVV-RLQLEATERQRGG-------AEGELQALRARAEEAEAQKRQAQEEAERLRRQVQ 1531
Query: 596 KEPKDEAQNEGPAT-----ESEAPLKEDGLLP--KPLSSGGEEEEKPRGEASEDLCEMAL 648
E + + Q E E+EA ++ L + L EE E+ +A + +
Sbjct: 1532 DESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQ-V 1590
Query: 649 DPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLA 708
L + E E + +E + + E ++ + +E + A +
Sbjct: 1591 QVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAE---- 1646
Query: 709 FVFFDANWCGYLHRRDLERILL----TLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQ 764
A R+LER L L +RL AE+ Q S + + + + +
Sbjct: 1647 -----AERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAE---AEKQKEEAER 1698
Query: 765 EGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDS 824
E G EE +L + + A T + L + LI + + ++ EQQ
Sbjct: 1699 EARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQ-ELIRLRAETEQGEQQ-- 1755
Query: 825 GRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR-TAERQKS 883
R LE ++ L+ + + + E + AEM+ L A AEE +R T+E+ K
Sbjct: 1756 -RQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQ 1814
Query: 884 QLQ------RLLQELRRRLTPLQLEIQRVVEKAD 911
+L+ R L E RL L E +R + A+
Sbjct: 1815 RLEAEAGRFRELAEEAARLRALAEEAKRQRQLAE 1848
Score = 45.8 bits (107), Expect = 2e-04
Identities = 32/102 (31%), Positives = 54/102 (52%), Gaps = 8/102 (7%)
Query: 817 QRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETAR 876
++AE + RL +E +I + L+LE ATE E+Q LR R EAE R
Sbjct: 1465 RQAEAAERSRLRIEEEIRVVRLQLE-------ATERQRGGAEGELQALRARAEEAEAQKR 1517
Query: 877 TAERQKSQLQRLLQELRRRLTPLQLEI-QRVVEKADSWVEKE 917
A+ + +L+R +Q+ +R ++E+ RV +A++ EK+
Sbjct: 1518 QAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQ 1559
Score = 38.9 bits (89), Expect = 0.022
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 7/111 (6%)
Query: 814 SLLQRAE--QQDSGRL--YLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLA 869
SLLQR +Q+ +L ++++ + EE + E + L A M+E R R
Sbjct: 2528 SLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQH 2587
Query: 870 EAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPA 920
EAEE R R++ +LQ+L Q+ R++ L E QR+ E+ E+ A
Sbjct: 2588 EAEEGVR---RKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAA 2635
Score = 35.4 bits (80), Expect = 0.25
Identities = 82/382 (21%), Positives = 138/382 (36%), Gaps = 56/382 (14%)
Query: 522 GIVEDR-RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK 580
G+VED R + ++ E++ L F + G ++ L KE+A
Sbjct: 1938 GLVEDTLRQRRQVEEEILALKASFEKAAA---GKAELELELGRIRSNAEDTLRSKEQAEL 1994
Query: 581 EEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGE 638
E A + + A +EE + +E + A E EA + L + L + EE + R
Sbjct: 1995 EAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRER 2054
Query: 639 ASEDLC-EMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDP 697
A ++ ++ L E R EE+ ++ E + Q E S L + E +
Sbjct: 2055 AEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQ--SVLDQLRGEAEA 2112
Query: 698 SAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYR 757
+ RR E AE+A+ R Q+ Q
Sbjct: 2113 A-----------------------RRAAEE----------AEEARVQAEREAAQSRRQVE 2139
Query: 758 SLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQ 817
+ +Q + + L + A E AL + + +
Sbjct: 2140 EAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199
Query: 818 RAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETART 877
AEQ + +E ++ TL L+LEE T+ L E+Q L+ AEA E A
Sbjct: 2200 FAEQTLRQKAQVEQELTTLRLQLEE-------TDHQKNLLDEELQRLK---AEATEAA-- 2247
Query: 878 AERQKSQLQRLLQELRRRLTPL 899
RQ+SQ++ L +R ++ L
Sbjct: 2248 --RQRSQVEEELFSVRVQMEEL 2267
Score = 34.3 bits (77), Expect = 0.55
Identities = 108/494 (21%), Positives = 182/494 (36%), Gaps = 65/494 (13%)
Query: 440 EALCQQKA---AEAAPPTQEAQGET----EPTEQAPDALEQAADTSRRNAETPEATTQQE 492
E + QQK+ AEA +EA+ E + EQA E A + + E T QQ
Sbjct: 1676 EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQR 1735
Query: 493 -----------TDTDLPEAPPPPLEP--AVIARPGCVNLSLHGIVEDRRPKERISFEVMV 539
+T+ E LE A + R +E K R EV++
Sbjct: 1736 LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLL 1795
Query: 540 LAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP- 598
++ E R + + L E EEAA+ A EE + ++ +E
Sbjct: 1796 ASKARAEEESRSTSEKSKQRL----EAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDA 1851
Query: 599 -KDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRD 657
+ A+ E E A + E L + E K + +E L +A D R
Sbjct: 1852 ARQRAEAERVLAEKLAAIGE----ATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRL 1907
Query: 658 DGEEEFAGAKLED--SEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDAN 715
+ + A +E+ +++R + ++ E + ++D ++ + + L F+
Sbjct: 1908 EEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQ---RRQVEEEILALKASFEKA 1964
Query: 716 WCGYLHRRDLERILLTLG-IRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEE 774
G + +LE L LG IR +AE + + + R Q + +E EE
Sbjct: 1965 AAG---KAELE---LELGRIRSNAEDTLRSKEQAELEAA---RQRQLAAEEERRRREAEE 2015
Query: 775 VLFGNLDLLPPPGKSTKPGAAPTEH-KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKI 833
+ +L + K E KA V L +RAEQ+ + +L L +
Sbjct: 2016 RVQKSLAAEEEAARQRKAALEEVERLKAKVEE------ARRLRERAEQESARQLQLAQEA 2069
Query: 834 HTLELKLEESHNRFSATEVTNKT-------------LAAEMQELRVRLAEAEETARTAER 880
L+ EE + F+ + + L E + R EAEE AER
Sbjct: 2070 AQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAER 2129
Query: 881 QKSQLQRLLQELRR 894
+ +Q +R ++E R
Sbjct: 2130 EAAQSRRQVEEAER 2143
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 47.0 bits (110), Expect = 8e-05
Identities = 56/209 (26%), Positives = 96/209 (45%), Gaps = 47/209 (22%)
Query: 444 QQKAAEAAPPTQE---AQGETEPTEQAPDA-LEQAADTSRRNAETPEATTQQETDTDLPE 499
+++ A A P T+E ++ E P ++AP +E+ + + + + ++E D +
Sbjct: 843 EEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKK 902
Query: 500 APPPPLE-PAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYK 558
P P E PA + + ED +PKE+ E+ +++
Sbjct: 903 VPTPEKEAPAKVE-----------VKEDAKPKEKT------------EVAKKE------- 932
Query: 559 MLLSLPE--KVVSPPEP-EKEEAAKEEA-TKEEEAIKEEVVKEPKDEAQ-NEGPATESEA 613
P+ K P +P EK+EAA E+ TKEE+A K E ++PK EA+ E T S+
Sbjct: 933 -----PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPE--EKPKTEAKAKEDDKTLSKE 985
Query: 614 PLKEDGLLPKPLSSGGEEEEKPRGEASED 642
P K + SS +++ KP +A+ED
Sbjct: 986 PSKPKAEKAEKSSSTDQKDSKPPEKATED 1014
Score = 45.8 bits (107), Expect = 2e-04
Identities = 45/219 (20%), Positives = 88/219 (40%), Gaps = 4/219 (1%)
Query: 434 PTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQET 493
P EE ++ + K+ E A + + ++ P ++P+ E + ++ E ++ ++E
Sbjct: 533 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA 592
Query: 494 DTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFG 553
+ P + V + + E+ + + + E +
Sbjct: 593 KSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652
Query: 554 YRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP-KDEAQNEGPATESE 612
K PEK SP + E + K ++ + EA E K P K+EA++ A +
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKA---K 709
Query: 613 APLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPE 651
+P+KE+ P+ S +EE K +A + E A PE
Sbjct: 710 SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPE 748
Score = 40.4 bits (93), Expect = 0.008
Identities = 52/229 (22%), Positives = 89/229 (38%), Gaps = 35/229 (15%)
Query: 434 PTLEEWEALCQQKAA---EAAPPTQEAQGET--EPTEQAPDALEQAADTSRRNAETPE-A 487
P EE ++ + K+ EA P + E PT++ + E+A + A++PE A
Sbjct: 607 PVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 488 TTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEM 547
+ + + PE P++ A + + E+ + E+ V A+
Sbjct: 667 KSPVKAEAKSPEKAKSPVK----AEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKS---- 718
Query: 548 LQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGP 607
PEK SP + E + K ++ +EEA E K P+ +
Sbjct: 719 ----------------PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVK 762
Query: 608 ATESEAPLKEDG-----LLPKPLSSGGEEEEKPRGEASEDLCEMALDPE 651
+ E++ P KE+ P+ S +EE K +A L E A PE
Sbjct: 763 SPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPE 811
Score = 39.7 bits (91), Expect = 0.013
Identities = 24/71 (33%), Positives = 38/71 (53%), Gaps = 6/71 (8%)
Query: 574 EKEEAAKEEATKEEEAIKEEVVKEPKDEAQNE------GPATESEAPLKEDGLLPKPLSS 627
E+E+ AKEE KEEE +EE + ++E ++ P E+++P+KE+ P S
Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKS 532
Query: 628 GGEEEEKPRGE 638
+EE K E
Sbjct: 533 PEKEEAKSPAE 543
Score = 38.1 bits (87), Expect = 0.038
Identities = 25/86 (29%), Positives = 37/86 (43%)
Query: 565 EKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP 624
EK+ + EKE EE T+E + +E +E K+ + EG E + +G +
Sbjct: 442 EKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEET 501
Query: 625 LSSGGEEEEKPRGEASEDLCEMALDP 650
S EE P EA + E A P
Sbjct: 502 KSPPAEEAASPEKEAKSPVKEEAKSP 527
Score = 35.4 bits (80), Expect = 0.25
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 2/77 (2%)
Query: 562 SLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLL 621
S P + + PE E + KEEA EA K +E K A+ + P ++++P KE+
Sbjct: 503 SPPAEEAASPEKEAKSPVKEEAKSPAEA-KSPEKEEAKSPAEVKSPE-KAKSPAKEEAKS 560
Query: 622 PKPLSSGGEEEEKPRGE 638
P S +EE K E
Sbjct: 561 PPEAKSPEKEEAKSPAE 577
Score = 35.0 bits (79), Expect = 0.32
Identities = 38/143 (26%), Positives = 61/143 (42%), Gaps = 19/143 (13%)
Query: 566 KVVSPPEPEKEEAAKEEATKEE-EAIKEEVVKEPKD----------EAQNEGPATESEAP 614
K + +KEEA K+EA K + E KE V++PK+ E + + P E EAP
Sbjct: 852 KTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP 911
Query: 615 ----LKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLED 670
+KED KP +++P +++ + A E + D +EE A K E+
Sbjct: 912 AKVEVKEDA---KPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKA-KKPEE 967
Query: 671 SEVRSVASNQSEMEFSSLQDMPK 693
+ + + S PK
Sbjct: 968 KPKTEAKAKEDDKTLSKEPSKPK 990
Score = 34.3 bits (77), Expect = 0.55
Identities = 46/214 (21%), Positives = 71/214 (33%), Gaps = 44/214 (20%)
Query: 426 LPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETP 485
+P V T + E + +K+ + +E ET+ TE+ + E+ + +
Sbjct: 429 IPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTE--EEEKEAKEEEGKEE 486
Query: 486 EATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFL 545
E ++E + E PP E A A P ++ K + E AE
Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEA--ASP------------EKEAKSPVKEEAKSPAEA-- 530
Query: 546 EMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNE 605
PEKEEA K E K +E K + +
Sbjct: 531 -------------------------KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK 565
Query: 606 GPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEA 639
P E EA + P+ S +EE K EA
Sbjct: 566 SPEKE-EAKSPAEVKSPEKAKSPAKEEAKSPAEA 598
Score = 33.5 bits (75), Expect = 0.94
Identities = 62/247 (25%), Positives = 93/247 (37%), Gaps = 43/247 (17%)
Query: 440 EALCQQKAAEAAPPTQEAQGETE---PTEQAPDALEQAADTSRRNAETPEATTQQET--- 493
EA +KA +P +EA+ + P ++ E+A + A++PE E
Sbjct: 701 EAKSPEKAK--SPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKT 758
Query: 494 -DTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDF 552
D PEA P E A R P ++ F + + E+ +
Sbjct: 759 LDVKSPEAKTPAKEEA------------------RSPADK--FPEKAKSPVKEEVKSPEK 798
Query: 553 GYRVYKMLLSLPEKVVSPPE----PEKEEAAKEEATKEEEAIKEEVVKEP-KDEAQNEGP 607
K PEK + E P KEE +E +E K E K P + + +
Sbjct: 799 AKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 608 ATESEAPLKEDGLLPKPLSSGGEEE--EKPRGEASEDLCEMALDPELLLLRDDGEEEFAG 665
+ + EAP KE PKP +E EKP+ E E A D + + E+ A
Sbjct: 859 SKKEEAPKKE---APKPKVEEKKEPAVEKPKESKVEAKKEEAEDKK----KVPTPEKEAP 911
Query: 666 AKLEDSE 672
AK+E E
Sbjct: 912 AKVEVKE 918
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 45.1 bits (105), Expect = 3e-04
Identities = 38/121 (31%), Positives = 62/121 (51%), Gaps = 9/121 (7%)
Query: 804 SHNGSL-INVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQ 862
SHN L + + L QR E+ + L+ E +L+E ++ + E N +L AE++
Sbjct: 326 SHNRQLRLKLVGLTQRIEELEETNKNLQKA----EEELQELRDKIAKGECGNSSLMAEVE 381
Query: 863 ELRVRLAEAE---ETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEP 919
LR R+ E E E E Q +L++ LQE L+LE+++ ++K S +EK E
Sbjct: 382 NLRKRVLEMEGKDEEITKTESQCRELRKKLQEEEHHSKELRLEVEK-LQKRMSELEKLEE 440
Query: 920 A 920
A
Sbjct: 441 A 441
Score = 30.4 bits (67), Expect = 7.9
Identities = 16/65 (24%), Positives = 33/65 (50%)
Query: 830 ENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLL 889
E+K + EE + + + E N+ L ++ L R+ E EET + ++ + +LQ L
Sbjct: 304 EHKASRFSQEHEEMNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEELQELR 363
Query: 890 QELRR 894
++ +
Sbjct: 364 DKIAK 368
>gi|149999615 variable charge, X-linked 3B [Homo sapiens]
Length = 216
Score = 44.7 bits (104), Expect = 4e-04
Identities = 43/144 (29%), Positives = 65/144 (45%), Gaps = 20/144 (13%)
Query: 563 LPEKVVSPPEPEKE----EAAKEEATKEEEAIKEEVVKEP-KDEAQNEGPAT---ESEAP 614
LP+ + P EP E + +E+ EE +E V+EP E+Q E P + E E P
Sbjct: 84 LPQHELPPEEPVSEGTQHDPLSQESELEEPLSQESEVEEPLSQESQVEEPLSQESEVEEP 143
Query: 615 LKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVR 674
L ++ + +PLS E EE E+ + E L + EE + ++S+V
Sbjct: 144 LSQESQVEEPLSQESEVEEPLSQESQVE--------EPLSQESEMEEPLS----QESQVE 191
Query: 675 SVASNQSEMEFSSLQDMPKELDPS 698
S +SEME Q+ E PS
Sbjct: 192 EPLSQESEMEEPLSQESEMEELPS 215
Score = 38.1 bits (87), Expect = 0.038
Identities = 47/206 (22%), Positives = 74/206 (35%), Gaps = 20/206 (9%)
Query: 446 KAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPL 505
KA EA +Q ++ + + RR + + PEA P
Sbjct: 13 KAKEAGKRKSSSQPSPSDPKKKTTKVAKKGKAVRRGRRGKKGAATKMAAVTAPEAESGPA 72
Query: 506 EPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPE 565
P +P L H + + E + + E L ++ + LS
Sbjct: 73 APGPSDQPS-QELPQHELPPEEPVSEGTQHDPLSQESELEEPLSQE---SEVEEPLSQES 128
Query: 566 KVVSP--PEPEKEEAAKEEATKEEEAIKEEVVKEP-KDEAQNEGPATES----------- 611
+V P E E EE +E+ EE +E V+EP E+Q E P ++
Sbjct: 129 QVEEPLSQESEVEEPLSQESQVEEPLSQESEVEEPLSQESQVEEPLSQESEMEEPLSQES 188
Query: 612 --EAPLKEDGLLPKPLSSGGEEEEKP 635
E PL ++ + +PLS E EE P
Sbjct: 189 QVEEPLSQESEMEEPLSQESEMEELP 214
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 44.7 bits (104), Expect = 4e-04
Identities = 32/104 (30%), Positives = 49/104 (47%), Gaps = 11/104 (10%)
Query: 571 PEPEK--EEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSG 628
PEP+ EE + A++EE ++E EPK++A +E ES+ + ED +P
Sbjct: 178 PEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAKAEPKEPD 237
Query: 629 GEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSE 672
G+EE K + D E A +D EE G+ E+ E
Sbjct: 238 GKEEAKHGAKEEADAKEEA---------EDAEEAEPGSPSEEQE 272
Score = 38.1 bits (87), Expect = 0.038
Identities = 53/203 (26%), Positives = 78/203 (38%), Gaps = 36/203 (17%)
Query: 449 EAAPPTQEAQGETEPTEQAPDALEQAADT---SRRNAETPEATTQQETDTDLPEAPPPPL 505
E +QE G E T+ P E+ T ++ AE EA + D + P
Sbjct: 121 ETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRDKP-- 178
Query: 506 EPAVIARPGCVNLSLHGIVEDRR-----PKERISFEVMVLAELFLEMLQRDFGYRVYKML 560
EP + R+ PKE+ + E AE +++
Sbjct: 179 EPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEE-AKAESQKAVVE----------- 226
Query: 561 LSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKED-- 618
E P EP+ +E AK A KEE KEE E +EA+ P+ E E ++++
Sbjct: 227 ---DEAKAEPKEPDGKEEAKHGA-KEEADAKEEA--EDAEEAEPGSPSEEQEQDVEKEPE 280
Query: 619 ---GLLPKPLSSGGEEEEKPRGE 638
G++P SS E E P GE
Sbjct: 281 GGAGVIP---SSPEEWPESPTGE 300
Score = 30.8 bits (68), Expect = 6.1
Identities = 48/182 (26%), Positives = 70/182 (38%), Gaps = 51/182 (28%)
Query: 572 EPEKEEAAKEEATKEEEAI--------KEEVVKEPKDEAQNEG-------PATESEAPLK 616
E + E KE+ KEE + KEE EPK+ + E A E EA +
Sbjct: 106 EDAEAELKKEDGEKEETTVGSQEMTGRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPE 165
Query: 617 -------EDGLLPKPLSSGGEEEEK--------PRGEASEDLCEMALDPEL------LLL 655
D P+P ++ EE+ K R E S + E A D E ++
Sbjct: 166 SGQKADANDRDKPEPKATVEEEDAKTASQEETGQRKECSTEPKEKATDEEAKAESQKAVV 225
Query: 656 RD---------DGEEEFAGAKLEDSEVRSVASNQSEMEFSS-----LQDMPKELDPSA-V 700
D DG+EE E+++ + A + E E S QD+ KE + A V
Sbjct: 226 EDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGV 285
Query: 701 LP 702
+P
Sbjct: 286 IP 287
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 44.3 bits (103), Expect = 5e-04
Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 15/168 (8%)
Query: 528 RPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEE 587
+PKE+ S +V E+ + + LL EK S E+EE +EE +EE
Sbjct: 2208 KPKEKFSSQVD-------EVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEE 2260
Query: 588 EAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMA 647
E +EE +E K+E + E E E K+ K +EE + + E E+ E+
Sbjct: 2261 EVREEE--EERKEEEEGEEKQVEKEEEEKK-----KKKKEKKKEEVQEKEEVFEEKEEIM 2313
Query: 648 LDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKEL 695
+ E L D+ EEE LE+ R + E +F + K L
Sbjct: 2314 SEEETESLSDEEEEE-ESCSLEEEVDREKEILKKEKQFKLQEQRRKSL 2360
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 43.9 bits (102), Expect = 7e-04
Identities = 65/315 (20%), Positives = 119/315 (37%), Gaps = 42/315 (13%)
Query: 403 WRFAEFQYLQPGPPRRLQTVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQ------E 456
W + + P PP+ +VW P A+ A++ APP + +
Sbjct: 161 WLEQNLERVLPQPPKS--------SEVWRDEP------AVATGAASDPAPPGRPQEMGPK 206
Query: 457 AQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPLEPAVIAR--PG 514
Q P+ P L+ + A P+ +Q +T + P P L V+ R
Sbjct: 207 LQARETPSLPTPIPLQPKEEPKEAPAPEPQPGSQAQTSSLPPTRDPARLVAWVLHRLEMA 266
Query: 515 CVNLSLHGIVEDRRPKERISFEVMVLA---------ELFLEMLQRDFGYRVYKMLLSLPE 565
LHG + ++ P +V ++ +L LE ++ + ++ + + P+
Sbjct: 267 LPQPVLHGKIGEQEPDSPGICDVQTISILPGGQVEPDLVLEEVEPPWE-DAHQDVSTSPQ 325
Query: 566 KVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPL 625
P E+E A E+ +E I+EE E ++E + E E + D + +
Sbjct: 326 GTEVVPAYEEENKAVEKMPRELSRIEEEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQV 385
Query: 626 SSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLE-DSEVRSVASNQSEME 684
G EE+ R +++ D L + GEE A+ + E VA ++E E
Sbjct: 386 GVGQSEEDGTRPQSTSD---------QKLWEEVGEEAKKEAEEKAKEEAEEVAEEEAEKE 436
Query: 685 FSSLQDMPKELDPSA 699
+ +E + A
Sbjct: 437 PQDWAETKEEPEAEA 451
Score = 30.4 bits (67), Expect = 7.9
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 14/86 (16%)
Query: 437 EEWEALCQQKAAEAAPPTQEAQGETEP-----TEQAPDALEQAADTSRRNAETPEATTQQ 491
EE + ++KA E A E + E EP T++ P+A +AA + + +
Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQVE 470
Query: 492 ETDTD-----LPEAPP----PPLEPA 508
+TD D E PP PP PA
Sbjct: 471 DTDADSCPLMAEENPPSTVLPPPSPA 496
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 43.9 bits (102), Expect = 7e-04
Identities = 71/305 (23%), Positives = 111/305 (36%), Gaps = 45/305 (14%)
Query: 434 PTLEEWEALC----QQKAAEAAPPTQEAQGETE------PTEQAPDALE-QAADTSRRNA 482
P L E E C A+PP T P E+ + + Q AD+
Sbjct: 975 PALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKSEPQDFQEADSWGDTK 1034
Query: 483 ETP--------EATTQ---QETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKE 531
TP E T + +E + E PPP P P ++ L G P +
Sbjct: 1035 RTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQ 1094
Query: 532 --RISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAK--EEATKEE 587
I FE+M E +L + + L +LP++ P +P+K+E + + + E
Sbjct: 1095 DKAIVFEIMEAGEPTGPILGAE---ALPGGLRTLPQE---PGKPQKDEVLRYPDRSLSPE 1148
Query: 588 EAIKEEVVKEPKDEAQNEGPATESEAPLKEDGL--------LPKPLSSGGEEEEKPRGEA 639
+A V+ P + N+ P +S L E L P+ S EE P E
Sbjct: 1149 DAESLSVLSVPSPDTANQEPTPKSPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKET 1208
Query: 640 SEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSA 699
S D+ L PE L G +F L E+ + + ++ +P+ +A
Sbjct: 1209 SLDVSSKQLSPESL-----GTLQFGELNLGKEEMGHLMQAEDTSHHTAPMSVPEPHAATA 1263
Query: 700 VLPLD 704
P D
Sbjct: 1264 SPPTD 1268
Score = 33.1 bits (74), Expect = 1.2
Identities = 58/249 (23%), Positives = 92/249 (36%), Gaps = 25/249 (10%)
Query: 437 EEWEALCQQKAAEAAPPTQE-AQGETEP-TEQAPDALEQAADTSRRNAETPEATTQQETD 494
E+ +A ++K + P ++ ++ + +P T + L +A R + A ++
Sbjct: 439 EKKDAKKEEKRKDTKPELKKISKPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKEL 498
Query: 495 TDLPEAPPP-----PLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQ 549
+ P+ PP PL P + V S + +D FE M E L Q
Sbjct: 499 SSEPQTPPAQKGTVPL-PTISGHRELVLSSPEDLTQD--------FEEMKREERALLAEQ 549
Query: 550 RDFGYRVYKMLLSL-----PEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEP--KDEA 602
RD G L P + P +EE +E+ + EV +E KD
Sbjct: 550 RDTGLGDKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGSKDRG 609
Query: 603 QNEGPATESEAPLKEDGLLPKP--LSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGE 660
+ G TE E E+ + L E E+ E ED+ E A E+ + E
Sbjct: 610 LDSGAETEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDE 669
Query: 661 EEFAGAKLE 669
EE K E
Sbjct: 670 EEEDATKAE 678
Score = 31.2 bits (69), Expect = 4.6
Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 20/122 (16%)
Query: 561 LSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGL 620
L+ E+VV E +E K E+ KE K P+ A+ E TES LK +
Sbjct: 334 LAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKR 393
Query: 621 -----------LPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDG-EEEFAGAKL 668
L + +S E+++K + E ++ E L +D+G +EE AK
Sbjct: 394 KLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKE--------LKKDEGRKEEKKDAKK 445
Query: 669 ED 670
E+
Sbjct: 446 EE 447
>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
Length = 555
Score = 43.5 bits (101), Expect = 0.001
Identities = 54/210 (25%), Positives = 86/210 (40%), Gaps = 14/210 (6%)
Query: 448 AEAAPPTQEAQGE--TEPTEQAPD-ALEQAADTSRRNAETPEATTQQET-DTDLPEAPPP 503
A + PPT GE +EP E+ + A Q + AE P+ T E + P P
Sbjct: 30 ASSGPPTSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGR 89
Query: 504 PLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSL 563
P EP +P + G E +P+ E + AE E L++ + + SL
Sbjct: 90 PAEP----QPEPEEPAEVGAEEPAQPEPGAGPEELE-AEAGAEELEQAAEGKEVRFQASL 144
Query: 564 PEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPK 623
P + E A+ E + EE KEE ++ + + +G +++ +E+G K
Sbjct: 145 PLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGEGRPAKS--QEEG---K 199
Query: 624 PLSSGGEEEEKPRGEASEDLCEMALDPELL 653
L E E+ E + L E L +LL
Sbjct: 200 RLYGRDEFEDLEWSEEVQKLQEQQLRSDLL 229
Score = 33.5 bits (75), Expect = 0.94
Identities = 35/131 (26%), Positives = 52/131 (39%), Gaps = 17/131 (12%)
Query: 570 PPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPA---------TESEAPLK---E 617
P E E+E+AA + T +E + + A EGP E E P + E
Sbjct: 47 PEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEEGPGEPGRPAEPQPEPEEPAEVGAE 106
Query: 618 DGLLPKPLSSGGEEEEKPRG----EASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEV 673
+ P+P +G EE E G E + + E+ L L R D EE A + E V
Sbjct: 107 EPAQPEP-GAGPEELEAEAGAEELEQAAEGKEVRFQASLPLTRIDEEEAAAAPEAETERV 165
Query: 674 RSVASNQSEME 684
++ E +
Sbjct: 166 EGEEEDKEETQ 176
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/258 (24%), Positives = 102/258 (39%), Gaps = 37/258 (14%)
Query: 431 TIMPTLEEWEALCQQKAAEAAP---PTQEAQGETEPTEQAPDALEQAADTSRRNAETPEA 487
T+ P +AL ++ P P Q +QG+ P + + + P
Sbjct: 592 TVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPR- 650
Query: 488 TTQQETDTDLPE----APPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAEL 543
++E+D P+ + PP E V P V LSL + +R + A L
Sbjct: 651 --RRESDPTGPQRQVFSVAPPFE--VNGLPRAVPLSL-----PYQDFKRDLSDYRERARL 701
Query: 544 FLEMLQRDFGYRVYKMLLSLPEKVVSPPEPE---KEEAAKEEATKEEEAIKEEVVKEPKD 600
+ + F + MLL+ P+ ++P +P+ KEE +EE +EEE EE +E ++
Sbjct: 702 LNRVRRVGFSH----MLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEE 757
Query: 601 EAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALD-----PELLLL 655
E + E E E L + L PR +S + E + D LL
Sbjct: 758 EEEEEEEEEEEEEEAAAAVALGEVLG--------PRSGSSSEGSERSTDRSQEGAPSTLL 809
Query: 656 RDDGEEEFAGAKLEDSEV 673
DD +E A + D ++
Sbjct: 810 ADDQKESRGRASMADGDL 827
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 42.4 bits (98), Expect = 0.002
Identities = 84/380 (22%), Positives = 154/380 (40%), Gaps = 50/380 (13%)
Query: 574 EKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGP--------ATESEAPLKEDGLLPKPL 625
E+E A + A KEE A +++ V+ + + Q + AT+ A L+ + L
Sbjct: 494 ERELTALKGALKEEVASRDQEVEHVRQQYQRDTEQLRRSMQDATQDHAVLEAERQKMSAL 553
Query: 626 SSGGEEEEKPRGEAS-----------EDLCEMALDPELLLLRDDGEE--EFAGAKLEDSE 672
G + E + E + EDL A ELL LR + EE E G K+E +
Sbjct: 554 VRGLQRELEETSEETGHWQSMFQKNKEDL--RATKQELLQLRMEKEEMEEELGEKIEVLQ 611
Query: 673 VRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTL 732
+ S + ++ + KEL + + L G R+LE+ L L
Sbjct: 612 RELEQARASAGDTRQVEVLKKELLRTQEELKE--LQAERQSQEVAGRHRDRELEKQLAVL 669
Query: 733 GIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKP 792
R+ A++ ++L QN+ ++LQ RQ+ + + V +L + +
Sbjct: 670 --RVEADRGRELEE----QNLQLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVET 723
Query: 793 GAAPTEH------KALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNR 846
T+ + ++ L L+ E ++ L +K+ LE + ++
Sbjct: 724 TLRETQEENDEFRRRILGLEQQLKETRGLVDGGEAVEAR---LRDKLQRLEAEKQQLEEA 780
Query: 847 FSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQE-------LRRRLTPL 899
+A++ +LAA + L RL EA+ +++ L R L+E LRR L
Sbjct: 781 LNASQEEEGSLAAAKRALEARLEEAQRGLARLGQEQQTLNRALEEEGKQREVLRRGKAEL 840
Query: 900 QLE---IQRVVEKADSWVEK 916
+ + + R V++ + +EK
Sbjct: 841 EEQKRLLDRTVDRLNKELEK 860
Score = 33.9 bits (76), Expect = 0.72
Identities = 23/92 (25%), Positives = 50/92 (54%), Gaps = 6/92 (6%)
Query: 829 LENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRL 888
LE++ L+ +L+ + + TN+ L +++EL +++ E+ + QK QL
Sbjct: 1050 LESQNQLLQERLQAEEREKTVLQSTNRKLERKVKELSIQI---EDERQHVNDQKDQLSLR 1106
Query: 889 LQELRRRLTPLQLEIQR---VVEKADSWVEKE 917
++ L+R++ + EI+R + +KA VE++
Sbjct: 1107 VKALKRQVDEAEEEIERLDGLRKKAQREVEEQ 1138
>gi|4506411 Ran GTPase activating protein 1 [Homo sapiens]
Length = 587
Score = 42.4 bits (98), Expect = 0.002
Identities = 57/236 (24%), Positives = 97/236 (41%), Gaps = 19/236 (8%)
Query: 518 LSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDF-GYRVYKMLLSLP------EKVVSP 570
L++ + D+ E++ L E E LQ G+ + K+L SL E+
Sbjct: 311 LAVAEAMADKAELEKLDLNGNTLGEEGCEQLQEVLEGFNMAKVLASLSDDEDEEEEEEGE 370
Query: 571 PEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGE 630
E E+ E +EE +EEE +EE +EP+ Q E AT S L + P P+ S
Sbjct: 371 EEEEEAEEEEEEDEEEEEEEEEEEEEEPQQRGQGEKSATPSRKILDPNTGEPAPVLS--- 427
Query: 631 EEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQD 690
P + S L + PE LL + + S+ V S + ++ SS+
Sbjct: 428 --SPPPADVSTFLAFPS--PEKLLRLGPKSSVLIAQQTDTSDPEKVVS--AFLKVSSVFK 481
Query: 691 MPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVS 746
+ + +D L+ F N + L R+L+ +G+ S ++ K + +
Sbjct: 482 DEATVRMAVQDAVDALMQKAF---NSSSFNSNTFLTRLLVHMGLLKSEDKVKAIAN 534
>gi|189409130 zinc finger E-box binding homeobox 1 isoform a [Homo
sapiens]
Length = 1108
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 5/72 (6%)
Query: 574 EKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEE 633
E++E K + +EEE +EEV +E +EA+NEG ++E +K+D + S G
Sbjct: 1036 EEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLG----- 1090
Query: 634 KPRGEASEDLCE 645
+ GE+SE + E
Sbjct: 1091 QKVGESSEQVSE 1102
Score = 33.1 bits (74), Expect = 1.2
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 22/126 (17%)
Query: 569 SPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSG 628
SP + + +E ++E++ KEE E +D+ E L+E+ KP G
Sbjct: 1000 SPSQGDSDERESLTREEDEDSEKEE---EEEDKEMEE---------LQEEKECEKP--QG 1045
Query: 629 GEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSL 688
EEEE+ E E+ E A ++GEE ++D S AS+ + S
Sbjct: 1046 DEEEEEEEEEVEEEEVEEA--------ENEGEEAKTEGLMKDDRAESQASSLGQKVGESS 1097
Query: 689 QDMPKE 694
+ + +E
Sbjct: 1098 EQVSEE 1103
Score = 31.6 bits (70), Expect = 3.6
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 13/110 (11%)
Query: 575 KEEAAKEEATKEEEAIKEEVVKEPKDE--AQNEGPATESEAPLKEDGLLPKPLSSGGEEE 632
K EA + ++T++EEA E + E + ++G + E E+ +E+ E+E
Sbjct: 971 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREE-------DEDSEKE 1023
Query: 633 EKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSE 682
E+ + E+L E + E + D EEE ++E+ EV A N+ E
Sbjct: 1024 EEEEDKEMEELQE---EKECEKPQGDEEEEEEEEEVEEEEVEE-AENEGE 1069
>gi|189409128 zinc finger E-box binding homeobox 1 isoform b [Homo
sapiens]
Length = 1124
Score = 42.0 bits (97), Expect = 0.003
Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 5/72 (6%)
Query: 574 EKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEE 633
E++E K + +EEE +EEV +E +EA+NEG ++E +K+D + S G
Sbjct: 1052 EEKECEKPQGDEEEEEEEEEVEEEEVEEAENEGEEAKTEGLMKDDRAESQASSLG----- 1106
Query: 634 KPRGEASEDLCE 645
+ GE+SE + E
Sbjct: 1107 QKVGESSEQVSE 1118
Score = 33.1 bits (74), Expect = 1.2
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 22/126 (17%)
Query: 569 SPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSG 628
SP + + +E ++E++ KEE E +D+ E L+E+ KP G
Sbjct: 1016 SPSQGDSDERESLTREEDEDSEKEE---EEEDKEMEE---------LQEEKECEKP--QG 1061
Query: 629 GEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSL 688
EEEE+ E E+ E A ++GEE ++D S AS+ + S
Sbjct: 1062 DEEEEEEEEEVEEEEVEEA--------ENEGEEAKTEGLMKDDRAESQASSLGQKVGESS 1113
Query: 689 QDMPKE 694
+ + +E
Sbjct: 1114 EQVSEE 1119
Score = 31.6 bits (70), Expect = 3.6
Identities = 30/110 (27%), Positives = 53/110 (48%), Gaps = 13/110 (11%)
Query: 575 KEEAAKEEATKEEEAIKEEVVKEPKDE--AQNEGPATESEAPLKEDGLLPKPLSSGGEEE 632
K EA + ++T++EEA E + E + ++G + E E+ +E+ E+E
Sbjct: 987 KREAEERDSTEQEEAGPEILSNEHVGARASPSQGDSDERESLTREE-------DEDSEKE 1039
Query: 633 EKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSE 682
E+ + E+L E + E + D EEE ++E+ EV A N+ E
Sbjct: 1040 EEEEDKEMEELQE---EKECEKPQGDEEEEEEEEEVEEEEVEE-AENEGE 1085
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 8/153 (5%)
Query: 542 ELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDE 601
E+ E D + + L ++ E++ + EK+EAA+E+ +EE +EE V K
Sbjct: 455 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEK--EEEPEAEEEEVAAKKSP 512
Query: 602 AQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEE 661
+ P + E KE+ EEEE+ G S+ E + E +++GE+
Sbjct: 513 VKATAPEVKEEEGEKEEE------EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 566
Query: 662 EFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKE 694
E + E + A + ++E S + KE
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 599
Score = 38.5 bits (88), Expect = 0.029
Identities = 22/64 (34%), Positives = 33/64 (51%)
Query: 572 EPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEE 631
E E +E K E EE A KEE+V + K E + + ++P++E G P P S E+
Sbjct: 579 EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 638
Query: 632 EEKP 635
+ P
Sbjct: 639 GKSP 642
Score = 36.6 bits (83), Expect = 0.11
Identities = 54/251 (21%), Positives = 101/251 (40%), Gaps = 23/251 (9%)
Query: 455 QEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDL----PEAPPPPLEPAVI 510
++ +GETE + +A +A + + ++ E T++E D PE P+ + +
Sbjct: 565 EQEEGETEAEAEGEEA--EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 622
Query: 511 ARPGCVNLSLHGIVED-RRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVS 569
G + + E + P + E + + ++ V K + K
Sbjct: 623 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 682
Query: 570 PPEPEKE-----EAAKEEATKEEEAIKEEVVKEPKDEAQNEGPAT-----ESEAPLKEDG 619
P P +E E K E +EEE +E KE K E + E P ++E+P+KE+
Sbjct: 683 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 742
Query: 620 L-----LPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFA-GAKLEDSEV 673
+ + K + E+E K G+ + E ++G ++ A G++ ED V
Sbjct: 743 VAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAV 802
Query: 674 RSVASNQSEME 684
+ E+E
Sbjct: 803 NGEVEGKEEVE 813
Score = 35.4 bits (80), Expect = 0.25
Identities = 32/145 (22%), Positives = 57/145 (39%), Gaps = 16/145 (11%)
Query: 565 EKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP 624
+K + + E+ EA +EE ++ +K + ++E + E + E +++G
Sbjct: 488 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 547
Query: 625 LSSGGEEE----EKPRGEASEDLCEMALDPELLLLRDD------------GEEEFAGAKL 668
GG E+ EK GE E E + E +++ EE A AK+
Sbjct: 548 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 607
Query: 669 EDSEVRSVASNQSEMEFSSLQDMPK 693
E E +S +E +PK
Sbjct: 608 EKPEKAKSPVPKSPVEEKGKSPVPK 632
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 42.0 bits (97), Expect = 0.003
Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 8/153 (5%)
Query: 542 ELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDE 601
E+ E D + + L ++ E++ + EK+EAA+E+ +EE +EE V K
Sbjct: 79 EIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEK--EEEPEAEEEEVAAKKSP 136
Query: 602 AQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEE 661
+ P + E KE+ EEEE+ G S+ E + E +++GE+
Sbjct: 137 VKATAPEVKEEEGEKEEE------EGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 190
Query: 662 EFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKE 694
E + E + A + ++E S + KE
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKE 223
Score = 38.5 bits (88), Expect = 0.029
Identities = 22/64 (34%), Positives = 33/64 (51%)
Query: 572 EPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEE 631
E E +E K E EE A KEE+V + K E + + ++P++E G P P S E+
Sbjct: 203 EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEK 262
Query: 632 EEKP 635
+ P
Sbjct: 263 GKSP 266
Score = 36.6 bits (83), Expect = 0.11
Identities = 54/251 (21%), Positives = 101/251 (40%), Gaps = 23/251 (9%)
Query: 455 QEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDL----PEAPPPPLEPAVI 510
++ +GETE + +A +A + + ++ E T++E D PE P+ + +
Sbjct: 189 EQEEGETEAEAEGEEA--EAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 246
Query: 511 ARPGCVNLSLHGIVED-RRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVS 569
G + + E + P + E + + ++ V K + K
Sbjct: 247 EEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPV 306
Query: 570 PPEPEKE-----EAAKEEATKEEEAIKEEVVKEPKDEAQNEGPAT-----ESEAPLKEDG 619
P P +E E K E +EEE +E KE K E + E P ++E+P+KE+
Sbjct: 307 PKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEA 366
Query: 620 L-----LPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFA-GAKLEDSEV 673
+ + K + E+E K G+ + E ++G ++ A G++ ED V
Sbjct: 367 VAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAV 426
Query: 674 RSVASNQSEME 684
+ E+E
Sbjct: 427 NGEVEGKEEVE 437
Score = 35.4 bits (80), Expect = 0.25
Identities = 32/145 (22%), Positives = 57/145 (39%), Gaps = 16/145 (11%)
Query: 565 EKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKP 624
+K + + E+ EA +EE ++ +K + ++E + E + E +++G
Sbjct: 112 KKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQ 171
Query: 625 LSSGGEEE----EKPRGEASEDLCEMALDPELLLLRDD------------GEEEFAGAKL 668
GG E+ EK GE E E + E +++ EE A AK+
Sbjct: 172 AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKV 231
Query: 669 EDSEVRSVASNQSEMEFSSLQDMPK 693
E E +S +E +PK
Sbjct: 232 EKPEKAKSPVPKSPVEEKGKSPVPK 256
>gi|94721330 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 814 SLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEE 873
+L Q+ E+ + L + +K E L++ + ++ E + + M+++ RL +E
Sbjct: 343 ALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSER 402
Query: 874 TARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKE 917
+ AE + +LQ QEL R+ LQL++ ++ E+ S +EKE
Sbjct: 403 ARQGAEERSHKLQ---QELGGRIGALQLQLSQLHEQCSS-LEKE 442
Score = 31.6 bits (70), Expect = 3.6
Identities = 25/113 (22%), Positives = 56/113 (49%), Gaps = 14/113 (12%)
Query: 798 EHKALVSHNGSLINVGSLLQRAEQQ----DSGRLYLENKIHTLELKLEESHNRFSATEVT 853
+++A+ S G V S +++ E++ + R E + H L+ +E R A ++
Sbjct: 372 KNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQ---QELGGRIGALQL- 427
Query: 854 NKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRV 906
++ +L + + E+ ++ + Q+ LQR LQ + + L++E+Q+V
Sbjct: 428 ------QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQV 474
>gi|94721332 RUN and FYVE domain-containing 1 isoform b [Homo
sapiens]
Length = 600
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 814 SLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEE 873
+L Q+ E+ + L + +K E L++ + ++ E + + M+++ RL +E
Sbjct: 343 ALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSER 402
Query: 874 TARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKE 917
+ AE + +LQ QEL R+ LQL++ ++ E+ S +EKE
Sbjct: 403 ARQGAEERSHKLQ---QELGGRIGALQLQLSQLHEQCSS-LEKE 442
Score = 31.6 bits (70), Expect = 3.6
Identities = 25/113 (22%), Positives = 56/113 (49%), Gaps = 14/113 (12%)
Query: 798 EHKALVSHNGSLINVGSLLQRAEQQ----DSGRLYLENKIHTLELKLEESHNRFSATEVT 853
+++A+ S G V S +++ E++ + R E + H L+ +E R A ++
Sbjct: 372 KNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQ---QELGGRIGALQL- 427
Query: 854 NKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRV 906
++ +L + + E+ ++ + Q+ LQR LQ + + L++E+Q+V
Sbjct: 428 ------QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQV 474
>gi|94721336 RUN and FYVE domain-containing 1 isoform a [Homo
sapiens]
Length = 708
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/104 (26%), Positives = 55/104 (52%), Gaps = 4/104 (3%)
Query: 814 SLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEE 873
+L Q+ E+ + L + +K E L++ + ++ E + + M+++ RL +E
Sbjct: 451 ALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSER 510
Query: 874 TARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKE 917
+ AE + +LQ QEL R+ LQL++ ++ E+ S +EKE
Sbjct: 511 ARQGAEERSHKLQ---QELGGRIGALQLQLSQLHEQCSS-LEKE 550
Score = 31.6 bits (70), Expect = 3.6
Identities = 25/113 (22%), Positives = 56/113 (49%), Gaps = 14/113 (12%)
Query: 798 EHKALVSHNGSLINVGSLLQRAEQQ----DSGRLYLENKIHTLELKLEESHNRFSATEVT 853
+++A+ S G V S +++ E++ + R E + H L+ +E R A ++
Sbjct: 480 KNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQ---QELGGRIGALQL- 535
Query: 854 NKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRV 906
++ +L + + E+ ++ + Q+ LQR LQ + + L++E+Q+V
Sbjct: 536 ------QLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQV 582
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,996,269
Number of Sequences: 37866
Number of extensions: 2245013
Number of successful extensions: 16690
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 512
Number of HSP's that attempted gapping in prelim test: 12050
Number of HSP's gapped (non-prelim): 3728
length of query: 923
length of database: 18,247,518
effective HSP length: 112
effective length of query: 811
effective length of database: 14,006,526
effective search space: 11359292586
effective search space used: 11359292586
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.