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Search of human proteins with 40548332
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40548332 coiled-coil domain containing 137 [Homo sapiens]
(289 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40548332 coiled-coil domain containing 137 [Homo sapiens] 568 e-162
gi|148746195 trichohyalin [Homo sapiens] 55 7e-08
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 54 2e-07
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 54 2e-07
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 54 2e-07
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 54 2e-07
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 54 2e-07
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 54 2e-07
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 51 1e-06
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 47 2e-05
gi|104526627 triadin [Homo sapiens] 45 1e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 44 1e-04
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 44 2e-04
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho... 43 4e-04
gi|21735548 centrosomal protein 2 [Homo sapiens] 42 5e-04
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 42 5e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 41 0.001
gi|4505257 moesin [Homo sapiens] 41 0.001
gi|146260271 hypothetical protein LOC129881 [Homo sapiens] 41 0.001
gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform... 41 0.001
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 41 0.001
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 40 0.002
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 40 0.002
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 40 0.002
gi|22758136 MAP7 domain containing 2 [Homo sapiens] 40 0.002
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 40 0.002
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 40 0.002
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 40 0.003
gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 40 0.003
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 39 0.004
>gi|40548332 coiled-coil domain containing 137 [Homo sapiens]
Length = 289
Score = 568 bits (1464), Expect = e-162
Identities = 289/289 (100%), Positives = 289/289 (100%)
Query: 1 MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDE 60
MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDE
Sbjct: 1 MAGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDE 60
Query: 61 QEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGE 120
QEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGE
Sbjct: 61 QEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGE 120
Query: 121 SDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE 180
SDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE
Sbjct: 121 SDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE 180
Query: 181 EKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQP 240
EKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQP
Sbjct: 181 EKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQP 240
Query: 241 LTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQL 289
LTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQL
Sbjct: 241 LTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQL 289
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 55.1 bits (131), Expect = 7e-08
Identities = 58/266 (21%), Positives = 126/266 (47%), Gaps = 33/266 (12%)
Query: 44 RSKEKKKVNCKPKNQDE--QEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKE 101
R++E++ +CK +E E R RE++ R++ + ++R++ +V F++ EKE
Sbjct: 187 RAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRV-FQEEEEKE 245
Query: 102 AKGEEPDIAVPKFK--------QRKGESDGAYIHRM---------QQEAQHVLFLSKNQA 144
+ E + + K QR+ + + + ++ Q+E Q L + Q
Sbjct: 246 WRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQ 305
Query: 145 IR---QPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRL---EQELLRDTVKF 198
+R + E + +E+ EQ++ ++ ++RR ++RR++EE+ +L ++E R+
Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365
Query: 199 GEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERA 258
E + E R ++ + ++Q RR Q LR Q L +R + RE+
Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRR-------EQQLRREQQLRREQQLRREQQ 418
Query: 259 VQAYRALKQRQQQLHGERPHLTSRKK 284
++ + L++ Q++ E+ H R++
Sbjct: 419 LRREQQLRREQEEERHEQKHEQERRE 444
Score = 51.2 bits (121), Expect = 1e-06
Identities = 62/265 (23%), Positives = 124/265 (46%), Gaps = 28/265 (10%)
Query: 46 KEKKKVNCKPKNQDEQEIPFRLRE-IMRSRQEMKNPISNKKRKKAAQVTFRK-----TLE 99
+E ++ + + + EQE +R E + + +++ K+R++ + +RK E
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE 970
Query: 100 KEAKGEEPDIAVPKFKQRKGESDGAY--IHRMQQEAQHVLFLSKNQAIRQP-EVQAAPKE 156
++ GEEP+ K+R+ E + Y +QQE + +L + + RQ E Q K+
Sbjct: 971 EQLLGEEPE------KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKD 1024
Query: 157 KSEQKK---AKKAFQKRRL-DKVRRKKEEKAADRLEQELL---RDTVKFGEVVLQ---PP 206
+ +Q++ ++ +KRRL ++ R+ +EE+ + E++LL R+T + E+ Q
Sbjct: 1025 ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084
Query: 207 ELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYR--- 263
EL ++ + ++ RR Q Q L R+ + R+ + YR
Sbjct: 1085 ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEE 1144
Query: 264 ALKQRQQQLHGERPHLTSRKKPEPQ 288
++Q ++QL E P R++ E Q
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQ 1169
Score = 46.6 bits (109), Expect = 3e-05
Identities = 46/259 (17%), Positives = 108/259 (41%), Gaps = 20/259 (7%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLR---EIMRSRQEMKNPISNKKRKKAAQVTFRKTLEK 100
R +E+++ + ++E+ + RLR ++ R ++E + + ++ +K + R+ K
Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568
Query: 101 EAKGEEPDIAVPKFKQRKGES-------------DGAYIHRMQQEAQHVLFLSKNQAIRQ 147
+ E D + + ++R+ + + R++QE + L + + +
Sbjct: 569 REQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEE 628
Query: 148 PEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPE 207
Q E+ E+++ ++ ++++ + +R K E+ +RLEQ L R+ E + E
Sbjct: 629 RRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKRE----HEEERREQE 684
Query: 208 LTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQ 267
L Q + R + L S Q S R++ + R+ + R +
Sbjct: 685 LAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRES 744
Query: 268 RQQQLHGERPHLTSRKKPE 286
Q ER H +++ +
Sbjct: 745 ELQWQEEERAHRQQQEEEQ 763
Score = 46.2 bits (108), Expect = 3e-05
Identities = 56/258 (21%), Positives = 116/258 (44%), Gaps = 37/258 (14%)
Query: 46 KEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGE 105
+E+++ K + ++ ++ R E R QE + + +++ + + K LE+E + E
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK-LEEEERRE 498
Query: 106 EPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKK 165
+ + + ++ + E + R ++E + L Q +R+ E + ++ ++++ K+
Sbjct: 499 QQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRR-EQEERREQLLKREEEKR 557
Query: 166 AFQKRRLDKVRRKKEEKA-------------------ADRLEQELLRDTVKFGE------ 200
Q+RR +++R++EE+ +RLEQ L R+ V+ E
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617
Query: 201 --VVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEER-ER 257
+ + PE R Q S++Q RR Q LR Q +R EEER E+
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRR-------EQQERREQRLKREEEEERLEQ 670
Query: 258 AVQAYRALKQRQQQLHGE 275
++ ++R+Q+L E
Sbjct: 671 RLKREHEEERREQELAEE 688
Score = 46.2 bits (108), Expect = 3e-05
Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 16/249 (6%)
Query: 43 LRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKE- 101
L+ KE++ + +P+ + QE + RE +QE + + ++ K+ Q R+ +K+
Sbjct: 966 LQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025
Query: 102 -AKGEEPDIAVPKFKQRKGESDGAY--IHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKS 158
+ EE + + K+R E + Y +QQE + +L + RQ + KE+
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEE 1085
Query: 159 EQKKAKKAF-----QKRRLDKVRRKKEEKAADRLEQELLRD------TVKFGEVVLQPPE 207
Q++ ++ ++RR ++ R+ +EE+ + E++LLR+ + + E
Sbjct: 1086 LQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEE 1145
Query: 208 LTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQ 267
+ ++ + ++ RR Q L Q L R+ E+ R+ + YR ++
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE-QEKRRQERERQYREEEE 1204
Query: 268 RQQQLHGER 276
Q+Q +R
Sbjct: 1205 LQRQKRKQR 1213
Score = 45.4 bits (106), Expect = 6e-05
Identities = 56/263 (21%), Positives = 118/263 (44%), Gaps = 23/263 (8%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKR 86
QQ++ + R LRS+E ++ + + Q ++ R R+ ++ Q+++ ++R
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQ--RQRKFLQEEQQLRRQERGQQR 1549
Query: 87 KKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIR 146
++ FR+ + + EE ++ + + RK + + R +QE + F+ Q +R
Sbjct: 1550 RQDRDRKFREEEQLRQEREEQQLSRQE-RDRKFRLEEQKVRRQEQERK---FMEDEQQLR 1605
Query: 147 QPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPP 206
+ E Q +++ ++K R +++ +++EE+ R E++ KF E + P
Sbjct: 1606 RQEGQQQLRQERDRKF-------REDEQLLQEREEQQLHRQERDR-----KFLE---EEP 1650
Query: 207 ELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALK 266
+L + + + R+ + LL G Q R+ EE++ R + R
Sbjct: 1651 QLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFL 1710
Query: 267 QRQQQLHGERPHLTSRKKPEPQL 289
Q +QQL R L + + E QL
Sbjct: 1711 QEEQQL--RRQELERKFREEEQL 1731
Score = 45.1 bits (105), Expect = 7e-05
Identities = 49/260 (18%), Positives = 111/260 (42%), Gaps = 34/260 (13%)
Query: 48 KKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEP 107
+++ + + Q +E R + +R Q+++ ++ ++ Q+ + E+ + E
Sbjct: 384 RREQQLRREQQLRREQQLRREQQLRREQQLRR---EQQLRREQQLRREQEEERHEQKHEQ 440
Query: 108 DIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAF 167
+ + K R+ E ++ R ++ +H K Q R E + + +++ ++
Sbjct: 441 ERREQRLK-REQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499
Query: 168 QKRRLDKVRRKKEEKAADRL---------------EQELLRDTVKFGEVVLQPPELTA-- 210
Q+RR ++RR++EE+ RL EQ+L R+ + E +L+ E
Sbjct: 500 QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLE 559
Query: 211 --RPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQR 268
R ++ + ++Q RR Q+L+ +QR+ E+ ER Q + +
Sbjct: 560 QERREQRLKREQEERRDQLLKR-----------EEERRQQRLKREQEERLEQRLKREEVE 608
Query: 269 QQQLHGERPHLTSRKKPEPQ 288
+ + R R++PE +
Sbjct: 609 RLEQEERREQRLKREEPEEE 628
Score = 44.7 bits (104), Expect = 1e-04
Identities = 62/280 (22%), Positives = 120/280 (42%), Gaps = 57/280 (20%)
Query: 46 KEKKKVNCKPKNQD---EQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEA 102
KE++++ C+ + Q +++ FR E SRQE ++++ Q RK LE+E
Sbjct: 1394 KEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQ 1453
Query: 103 K---------GEEPDIAVPKFKQR--KGESDGAYIHRMQQ-----------------EAQ 134
+ EE + + +Q+ + E D ++ QQ +
Sbjct: 1454 QLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEP 1513
Query: 135 HVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVR--RKKEEKAADRLEQELL 192
FL + Q + + + Q ++ +Q + ++ Q+RR D+ R R++E+ +R EQ+L
Sbjct: 1514 ERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLS 1573
Query: 193 RDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVE 252
R R ++ ++Q RR + R + Q L +Q++ +
Sbjct: 1574 RQ---------------ERDRKFRLEEQKVRRQEQERKFMED---EQQLRRQEGQQQLRQ 1615
Query: 253 EERERAVQAYRALKQR-QQQLHGERPHLTSRK--KPEPQL 289
E + + + L++R +QQLH + RK + EPQL
Sbjct: 1616 ERDRKFREDEQLLQEREEQQLHRQE---RDRKFLEEEPQL 1652
Score = 44.3 bits (103), Expect = 1e-04
Identities = 51/261 (19%), Positives = 116/261 (44%), Gaps = 18/261 (6%)
Query: 33 GKQRPAPWPGLRSKEKKKVNCKPKNQDEQE-IPFRLREIMRSRQEMKNPISNKKRKKAAQ 91
G+QR + P LR + ++++ + + Q EQ +P + R RQ + + ++ Q
Sbjct: 780 GRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 92 VTFRKT---LEKEAKGEEPDIAVPKFKQRKGESDGAY-IHRMQQEAQHVLFLSKNQAIRQ 147
+ R+ L++E G + D + ++++ + + + ++ +H L+ +
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 148 PEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPE 207
+ Q +E+ E+ + ++ ++RR ++ R+ +EE+ + E++LLR + E
Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR----------EERE 949
Query: 208 LTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQ 267
R +R + + Q LL + + R EE ++ Q R ++
Sbjct: 950 KRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREERE 1009
Query: 268 RQQQLHGERPHLTSRKKPEPQ 288
++++ ER + RKK E Q
Sbjct: 1010 KRRRQEWERQY---RKKDELQ 1027
Score = 43.1 bits (100), Expect = 3e-04
Identities = 50/264 (18%), Positives = 118/264 (44%), Gaps = 25/264 (9%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAK 103
R + + + KP Q++ +L + +E++ K+R++ + +R+ E+ +
Sbjct: 882 RKRRRHTLYAKPALQEQLRKEQQL--LQEEEEELQREEREKRRRQEQERQYREE-EQLQQ 938
Query: 104 GEEPDIAVPKFKQRKGESDGAY--IHRMQQEAQHVL--------------FLSKNQAIRQ 147
EE + + K+R+ E + Y ++QQ+ + +L + + ++Q
Sbjct: 939 EEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQ 998
Query: 148 PEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPE 207
E Q +E+ ++++ + Q R+ D++++++E+ + E+ L++ + + E
Sbjct: 999 EEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER---QYREEEE 1055
Query: 208 LTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLAR---QRIVEEERERAVQAYRA 264
L ++ + +++ RR Q L Q L R ++ +ERER +
Sbjct: 1056 LQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 265 LKQRQQQLHGERPHLTSRKKPEPQ 288
L+Q ++QL E R++ E Q
Sbjct: 1116 LQQEEEQLLREEREKRRRQELERQ 1139
Score = 42.0 bits (97), Expect = 6e-04
Identities = 47/274 (17%), Positives = 120/274 (43%), Gaps = 17/274 (6%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK 85
RQ+++ ++ LR +++ + + + +++QE +E ++E + ++
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAI 145
+++ + R+ E+E + ++ ++ + E R +Q+ + L + Q +
Sbjct: 343 QEERREQQLRREQEEERREQQ-------LRREQEEERREQQLRREQQLRREQQLRREQQL 395
Query: 146 RQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEK------AADRLEQELLRDTVKFG 199
R+ + ++ +++ ++ Q RR ++RR++EE+ +R EQ L R+ +
Sbjct: 396 RREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455
Query: 200 EVVLQPPEL----TARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEER 255
+ + + E R ++ + +DQ R + L Q +R EE R
Sbjct: 456 DWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERR 515
Query: 256 ERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQL 289
E+ ++ ++ QQ+L E+ +++ QL
Sbjct: 516 EQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Score = 40.0 bits (92), Expect = 0.002
Identities = 55/285 (19%), Positives = 124/285 (43%), Gaps = 44/285 (15%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
R+ RG+Q+ Q ++ + +E+++++ + E++ FRL E RQE +
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLS-----RQERDRKFRLEEQKVRRQEQERK 1596
Query: 81 ISNKK---RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQ-------RKGESDGAYIHRMQ 130
+ R++ Q R+ +++ + +E + + +Q RK + + R +
Sbjct: 1597 FMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQE 1656
Query: 131 QEAQ-----HVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRR-------- 177
+E Q F + Q +++ E Q +++ ++K ++ Q RR ++ R+
Sbjct: 1657 REQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQL 1716
Query: 178 ---------KKEEKAADRLEQELLRDTVKFGEVVLQP---PELTARPQRSVSKDQPGRRS 225
++EE+ EQE LR ++ +++ + PE + R +D+ R
Sbjct: 1717 RRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREE 1776
Query: 226 QMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQ 270
+ LR Q L + + ++ EEE+ R + + L+ +Q+
Sbjct: 1777 EQLRQERE----EQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Score = 37.7 bits (86), Expect = 0.012
Identities = 33/155 (21%), Positives = 76/155 (49%), Gaps = 8/155 (5%)
Query: 18 GSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEM 77
G R R RQ+++ ++ L+ +E++ + +P+ + QE + RE +QE
Sbjct: 1065 GEERETRRRQELERQYRKEEE----LQQEEEQLLREEPEKRRRQERERQCREEEELQQEE 1120
Query: 78 KNPISNKKRKKAAQVTFRKTLEKEAKGEEPD--IAVPKFKQRKGESDGAY--IHRMQQEA 133
+ + ++ K+ Q R+ E+E +E + + K+R+ E + Y +QQE
Sbjct: 1121 EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE 1180
Query: 134 QHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQ 168
+ +L + + ++ E Q +E+ +++K K+ ++
Sbjct: 1181 EQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Score = 36.2 bits (82), Expect = 0.034
Identities = 64/288 (22%), Positives = 118/288 (40%), Gaps = 45/288 (15%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKN- 79
R+ R ++VQ +Q P R +++ + + + + +QE LRE R++ +
Sbjct: 1138 RQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERER 1197
Query: 80 ------PISNKKRKKA-------AQVTFRKTLEKE---------AKGEEPD----IAVPK 113
+ +KRK+ + + ++ EKE KG E + + +
Sbjct: 1198 QYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQ 1257
Query: 114 FKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLD 173
+ R+ + D ++ QQE + Q + + E+ EQK+AK+ +K + +
Sbjct: 1258 LRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEE 1317
Query: 174 K--VRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRML 231
K +R ++EEK R QE R KF E E +P R +D+ R ++
Sbjct: 1318 KQLLREEREEK---RRRQETDR---KFREEEQLLQEREEQPLRRQERDRKFREEELRHQ- 1370
Query: 232 LSPGGVSQPLTASLARQRIVEEERERAV---QAYRALKQRQQQLHGER 276
Q QR+ +ERER + ++R+QQL +R
Sbjct: 1371 ------EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDR 1412
Score = 33.1 bits (74), Expect = 0.29
Identities = 54/277 (19%), Positives = 117/277 (42%), Gaps = 25/277 (9%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
R+ R +++Q Q G + +++ + + + E+E+ +++R + P
Sbjct: 1048 RQYREEEELQ----QEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLR-----EEP 1098
Query: 81 ISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQ-QEAQHVLFL 139
+++++ Q + L++E EE + + K+R+ E + Y + Q+ + L
Sbjct: 1099 EKRRRQERERQCREEEELQQE---EEQLLREEREKRRRQELERQYREEEEVQQEEEQLLR 1155
Query: 140 SKNQAIRQPEVQAAPKEKSEQKKAKKAF-----QKRRLDKVRRKKEEKAADRLE-QELLR 193
+ + R+ E++ +E+ E ++ ++ +KRR ++ R+ +EE+ R + ++ R
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYR 1215
Query: 194 DTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRML----LSPGGVSQPLTASLARQ- 248
D + ++ Q R GR ++ R L L Q L L Q
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Query: 249 -RIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKK 284
R E+ER R Q R + +Q E+ R +
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDR 1312
Score = 33.1 bits (74), Expect = 0.29
Identities = 44/194 (22%), Positives = 85/194 (43%), Gaps = 24/194 (12%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK 85
RQ+ + +R + + +E+ + + + QE + RE + RQE ++
Sbjct: 1732 RQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE------REE 1785
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYI---HRMQQEAQHVLFLSKN 142
++ +Q + RK E+E +E + + +QR DG Y ++Q E Q +
Sbjct: 1786 QQLRSQESDRKFREEEQLRQEREEQQLRPQQR----DGKYRWEEEQLQLEEQEQRLRQER 1841
Query: 143 QAIRQPEVQAAPKEKS-----------EQKKAKKAFQKRRLDKVRRKKEEKAADRLEQEL 191
+ E Q A +EKS EQK+ ++ +K R + +RR+++E+ R E+
Sbjct: 1842 DRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEI 1901
Query: 192 LRDTVKFGEVVLQP 205
K +L+P
Sbjct: 1902 KSQEGKGHGRLLEP 1915
Score = 28.1 bits (61), Expect = 9.4
Identities = 29/140 (20%), Positives = 66/140 (47%), Gaps = 15/140 (10%)
Query: 147 QPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPP 206
+P + +E ++++ K+ Q+R L + + E++ +RLEQ RD + E + +
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQ--ERLEQ---RDRQRRDEELWR-- 175
Query: 207 ELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQ--PLTASLARQRIVEEERERAVQAYRA 264
QR +++ RR++ ++ G ++ P L R+ ++E R+ + +
Sbjct: 176 ------QRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQ 229
Query: 265 LKQRQQQLHGERPHLTSRKK 284
++RQ ++ E RK+
Sbjct: 230 RRERQDRVFQEEEEKEWRKR 249
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 53.9 bits (128), Expect = 2e-07
Identities = 60/268 (22%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEM--KNPISNK 84
+Q+Q L K + A +E+++ + K ++E+ R E+ R ++E+ + +
Sbjct: 718 EQLQQLEKAKAAKL----EQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEER 771
Query: 85 KRKKAAQVTFRKTLEKEAKGEEPDIAVPKFK-QRKGESDGAYIHRMQQEAQHVLFLSKNQ 143
KR++ ++ RK E + E +IA+ + + + + + + R+++ + K +
Sbjct: 772 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 831
Query: 144 AIRQPEVQAAPKEKSEQKKAKKAFQKRRL----DKVRRKKEEKAADRLEQELLRDTVKFG 199
+ + + + A K E+++A++ ++ RL + R + EE+ R E E+ R
Sbjct: 832 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK---- 887
Query: 200 EVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA-------SLARQRIVE 252
E++ Q + +R + Q + +QM S G TA SLA + +E
Sbjct: 888 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 947
Query: 253 EERERAV---------QAYRALKQRQQQ 271
EERER + + +AL+Q+QQQ
Sbjct: 948 EERERQLREEQRRQQRELMKALQQQQQQ 975
Score = 33.5 bits (75), Expect = 0.22
Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
Query: 143 QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVV 202
Q R+ E++A K + E++K ++ ++++ + +RR++EE+ R E+EL R +
Sbjct: 733 QERREAEMRA--KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 790
Query: 203 LQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAY 262
+ E+ R QR + Q ++ + LR L + ++ ++ ++ E A +
Sbjct: 791 QREQEIALRRQREEEERQ--QQEEALRRLEERRREEE---ERRKQEELLRKQEEEAAKWA 845
Query: 263 RALKQRQQQLHGER 276
R ++ Q++L R
Sbjct: 846 REEEEAQRRLEENR 859
Score = 32.0 bits (71), Expect = 0.65
Identities = 37/178 (20%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 116 QRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKV 175
Q+ ++ A + + ++EA+ + + RQ E++ +E +++ ++ ++ +
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
Query: 176 RRKKEEKAADRLEQEL-LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSP 234
RRK+EE + EQE+ LR + E Q L +R +++ ++ ++LR
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK---- 836
Query: 235 GGVSQPLTASLARQRIVEEERERAVQAYR------ALKQRQQQLHGERPHLTSRKKPE 286
+ A AR+ EEE +R ++ R A + R ++ +R L +++ E
Sbjct: 837 ---QEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 888
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 53.9 bits (128), Expect = 2e-07
Identities = 60/268 (22%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEM--KNPISNK 84
+Q+Q L K + A +E+++ + K ++E+ R E+ R ++E+ + +
Sbjct: 745 EQLQQLEKAKAAKL----EQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEER 798
Query: 85 KRKKAAQVTFRKTLEKEAKGEEPDIAVPKFK-QRKGESDGAYIHRMQQEAQHVLFLSKNQ 143
KR++ ++ RK E + E +IA+ + + + + + + R+++ + K +
Sbjct: 799 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 858
Query: 144 AIRQPEVQAAPKEKSEQKKAKKAFQKRRL----DKVRRKKEEKAADRLEQELLRDTVKFG 199
+ + + + A K E+++A++ ++ RL + R + EE+ R E E+ R
Sbjct: 859 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK---- 914
Query: 200 EVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA-------SLARQRIVE 252
E++ Q + +R + Q + +QM S G TA SLA + +E
Sbjct: 915 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 974
Query: 253 EERERAV---------QAYRALKQRQQQ 271
EERER + + +AL+Q+QQQ
Sbjct: 975 EERERQLREEQRRQQRELMKALQQQQQQ 1002
Score = 33.5 bits (75), Expect = 0.22
Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
Query: 143 QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVV 202
Q R+ E++A K + E++K ++ ++++ + +RR++EE+ R E+EL R +
Sbjct: 760 QERREAEMRA--KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 817
Query: 203 LQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAY 262
+ E+ R QR + Q ++ + LR L + ++ ++ ++ E A +
Sbjct: 818 QREQEIALRRQREEEERQ--QQEEALRRLEERRREEE---ERRKQEELLRKQEEEAAKWA 872
Query: 263 RALKQRQQQLHGER 276
R ++ Q++L R
Sbjct: 873 REEEEAQRRLEENR 886
Score = 32.0 bits (71), Expect = 0.65
Identities = 37/178 (20%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 116 QRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKV 175
Q+ ++ A + + ++EA+ + + RQ E++ +E +++ ++ ++ +
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
Query: 176 RRKKEEKAADRLEQEL-LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSP 234
RRK+EE + EQE+ LR + E Q L +R +++ ++ ++LR
Sbjct: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK---- 863
Query: 235 GGVSQPLTASLARQRIVEEERERAVQAYR------ALKQRQQQLHGERPHLTSRKKPE 286
+ A AR+ EEE +R ++ R A + R ++ +R L +++ E
Sbjct: 864 ---QEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 915
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 53.9 bits (128), Expect = 2e-07
Identities = 60/268 (22%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEM--KNPISNK 84
+Q+Q L K + A +E+++ + K ++E+ R E+ R ++E+ + +
Sbjct: 724 EQLQQLEKAKAAKL----EQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEER 777
Query: 85 KRKKAAQVTFRKTLEKEAKGEEPDIAVPKFK-QRKGESDGAYIHRMQQEAQHVLFLSKNQ 143
KR++ ++ RK E + E +IA+ + + + + + + R+++ + K +
Sbjct: 778 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 144 AIRQPEVQAAPKEKSEQKKAKKAFQKRRL----DKVRRKKEEKAADRLEQELLRDTVKFG 199
+ + + + A K E+++A++ ++ RL + R + EE+ R E E+ R
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK---- 893
Query: 200 EVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA-------SLARQRIVE 252
E++ Q + +R + Q + +QM S G TA SLA + +E
Sbjct: 894 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
Query: 253 EERERAV---------QAYRALKQRQQQ 271
EERER + + +AL+Q+QQQ
Sbjct: 954 EERERQLREEQRRQQRELMKALQQQQQQ 981
Score = 33.5 bits (75), Expect = 0.22
Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
Query: 143 QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVV 202
Q R+ E++A K + E++K ++ ++++ + +RR++EE+ R E+EL R +
Sbjct: 739 QERREAEMRA--KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 203 LQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAY 262
+ E+ R QR + Q ++ + LR L + ++ ++ ++ E A +
Sbjct: 797 QREQEIALRRQREEEERQ--QQEEALRRLEERRREEE---ERRKQEELLRKQEEEAAKWA 851
Query: 263 RALKQRQQQLHGER 276
R ++ Q++L R
Sbjct: 852 REEEEAQRRLEENR 865
Score = 32.0 bits (71), Expect = 0.65
Identities = 37/178 (20%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 116 QRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKV 175
Q+ ++ A + + ++EA+ + + RQ E++ +E +++ ++ ++ +
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 176 RRKKEEKAADRLEQEL-LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSP 234
RRK+EE + EQE+ LR + E Q L +R +++ ++ ++LR
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK---- 842
Query: 235 GGVSQPLTASLARQRIVEEERERAVQAYR------ALKQRQQQLHGERPHLTSRKKPE 286
+ A AR+ EEE +R ++ R A + R ++ +R L +++ E
Sbjct: 843 ---QEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 53.9 bits (128), Expect = 2e-07
Identities = 60/268 (22%), Positives = 124/268 (46%), Gaps = 33/268 (12%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEM--KNPISNK 84
+Q+Q L K + A +E+++ + K ++E+ R E+ R ++E+ + +
Sbjct: 724 EQLQQLEKAKAAKL----EQERREAEMRAKREEEERK--RQEELRRQQEEILRRQQEEER 777
Query: 85 KRKKAAQVTFRKTLEKEAKGEEPDIAVPKFK-QRKGESDGAYIHRMQQEAQHVLFLSKNQ 143
KR++ ++ RK E + E +IA+ + + + + + + R+++ + K +
Sbjct: 778 KRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQE 837
Query: 144 AIRQPEVQAAPKEKSEQKKAKKAFQKRRL----DKVRRKKEEKAADRLEQELLRDTVKFG 199
+ + + + A K E+++A++ ++ RL + R + EE+ R E E+ R
Sbjct: 838 ELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQK---- 893
Query: 200 EVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA-------SLARQRIVE 252
E++ Q + +R + Q + +QM S G TA SLA + +E
Sbjct: 894 ELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLE 953
Query: 253 EERERAV---------QAYRALKQRQQQ 271
EERER + + +AL+Q+QQQ
Sbjct: 954 EERERQLREEQRRQQRELMKALQQQQQQ 981
Score = 33.5 bits (75), Expect = 0.22
Identities = 30/134 (22%), Positives = 67/134 (50%), Gaps = 7/134 (5%)
Query: 143 QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVV 202
Q R+ E++A K + E++K ++ ++++ + +RR++EE+ R E+EL R +
Sbjct: 739 QERREAEMRA--KREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRR 796
Query: 203 LQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAY 262
+ E+ R QR + Q ++ + LR L + ++ ++ ++ E A +
Sbjct: 797 QREQEIALRRQREEEERQ--QQEEALRRLEERRREEE---ERRKQEELLRKQEEEAAKWA 851
Query: 263 RALKQRQQQLHGER 276
R ++ Q++L R
Sbjct: 852 REEEEAQRRLEENR 865
Score = 32.0 bits (71), Expect = 0.65
Identities = 37/178 (20%), Positives = 82/178 (46%), Gaps = 17/178 (9%)
Query: 116 QRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKV 175
Q+ ++ A + + ++EA+ + + RQ E++ +E +++ ++ ++ +
Sbjct: 727 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 786
Query: 176 RRKKEEKAADRLEQEL-LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSP 234
RRK+EE + EQE+ LR + E Q L +R +++ ++ ++LR
Sbjct: 787 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRK---- 842
Query: 235 GGVSQPLTASLARQRIVEEERERAVQAYR------ALKQRQQQLHGERPHLTSRKKPE 286
+ A AR+ EEE +R ++ R A + R ++ +R L +++ E
Sbjct: 843 ---QEEEAAKWARE---EEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKE 894
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/231 (20%), Positives = 110/231 (47%), Gaps = 19/231 (8%)
Query: 66 RLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAY 125
RLR+++++R+ ++ +++KK + F + EK K +E +A K K++
Sbjct: 577 RLRKVLQARERVEQ--MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 634
Query: 126 IH---RMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRL---------D 173
+ + ++EA+ + +L + + R+ + K++ EQ++ +KA + +RL +
Sbjct: 635 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 694
Query: 174 KVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPG---RRSQMLRM 230
+ RR++E + +R EQE + E + + + +R + + + ++ Q+ R
Sbjct: 695 QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRE 754
Query: 231 LLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTS 281
L + LA +++ EE+ ++A +A A K + + P TS
Sbjct: 755 LEEKKKKEE--QQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTS 803
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/153 (23%), Positives = 77/153 (50%), Gaps = 14/153 (9%)
Query: 45 SKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKG 104
+K+ ++V + K ++E RLR + + +E ++ +K+K+ Q RK E +
Sbjct: 629 AKKMEEVEARRKQEEEAR---RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 685
Query: 105 EEPD---IAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQK 161
E+ + + +Q + E + R +QE Q L++ + R+ E A +E E++
Sbjct: 686 EQREQERREQERREQERREQERREQERREQERQ----LAEQERRREQERLQAERELQERE 741
Query: 162 KA----KKAFQKRRLDKVRRKKEEKAADRLEQE 190
KA K+ Q+ +K +++++++ A+R QE
Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 774
Score = 29.6 bits (65), Expect = 3.2
Identities = 57/285 (20%), Positives = 104/285 (36%), Gaps = 48/285 (16%)
Query: 32 LGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQ 91
+ P P P S E + D+ + P + R ++ K +S
Sbjct: 408 IANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSE-------- 459
Query: 92 VTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQ 151
L++E E+ ++ P+ K + + R + H + +NQ + P
Sbjct: 460 ------LDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTV--QRNQMLMTPTSA 511
Query: 152 AAPKEKSEQKK-------AKKAF---QKRRLDKVRRKK----------EEKAADRLE--- 188
KS K+ K +F +++RL+ +RRK+ EE RLE
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKCSFVEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVK 571
Query: 189 ---QELLRDTVKFGEVVLQPPELTAR--PQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA 243
+E LR ++ E V Q E + Q+ D+ +++ R+ A
Sbjct: 572 LKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL----AEEKAKKKA 627
Query: 244 SLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQ 288
+ + VE R++ +A R +Q++ L +KK E Q
Sbjct: 628 AAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 672
Score = 29.3 bits (64), Expect = 4.2
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Query: 2 AGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQ 61
A + A R Q RR + R++ + ++R L +E+++ + + Q E+
Sbjct: 678 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERLQAER 735
Query: 62 EIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIA 110
E+ R + + +++++ + KK+K+ Q + L++E + + + A
Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 784
Score = 28.9 bits (63), Expect = 5.5
Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 34/196 (17%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK 85
R+ + L K++ LR + K + + Q+ +E R +E R QE +
Sbjct: 658 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE--RREQE--------R 707
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAI 145
R++ + R+ E+E R+ E + R QE + L L K Q
Sbjct: 708 REQERREQERQLAEQE---------------RRREQERLQAERELQEREKALRLQKEQLQ 752
Query: 146 RQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQP 205
R+ E + K+K EQ++ +R+L + + KK ++AA + L TV
Sbjct: 753 RELEEK---KKKEEQQR----LAERQLQEEQEKKAKEAAG--ASKALNVTVDVQSPACTS 803
Query: 206 PELTARPQRSVSKDQP 221
++T + R+ K P
Sbjct: 804 YQMTPQGHRAPPKINP 819
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 53.9 bits (128), Expect = 2e-07
Identities = 48/231 (20%), Positives = 110/231 (47%), Gaps = 19/231 (8%)
Query: 66 RLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAY 125
RLR+++++R+ ++ +++KK + F + EK K +E +A K K++
Sbjct: 573 RLRKVLQARERVEQ--MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEE 630
Query: 126 IH---RMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRL---------D 173
+ + ++EA+ + +L + + R+ + K++ EQ++ +KA + +RL +
Sbjct: 631 VEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERRE 690
Query: 174 KVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPG---RRSQMLRM 230
+ RR++E + +R EQE + E + + + +R + + + ++ Q+ R
Sbjct: 691 QERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRE 750
Query: 231 LLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTS 281
L + LA +++ EE+ ++A +A A K + + P TS
Sbjct: 751 LEEKKKKEE--QQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSPACTS 799
Score = 43.9 bits (102), Expect = 2e-04
Identities = 36/153 (23%), Positives = 77/153 (50%), Gaps = 14/153 (9%)
Query: 45 SKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKG 104
+K+ ++V + K ++E RLR + + +E ++ +K+K+ Q RK E +
Sbjct: 625 AKKMEEVEARRKQEEEAR---RLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLA 681
Query: 105 EEPD---IAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQK 161
E+ + + +Q + E + R +QE Q L++ + R+ E A +E E++
Sbjct: 682 EQREQERREQERREQERREQERREQERREQERQ----LAEQERRREQERLQAERELQERE 737
Query: 162 KA----KKAFQKRRLDKVRRKKEEKAADRLEQE 190
KA K+ Q+ +K +++++++ A+R QE
Sbjct: 738 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
Score = 32.3 bits (72), Expect = 0.50
Identities = 54/281 (19%), Positives = 104/281 (37%), Gaps = 44/281 (15%)
Query: 32 LGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQ 91
+ P P P S E + D+ + P + R ++ K +S
Sbjct: 408 IANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSE-------- 459
Query: 92 VTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPE-- 149
L++E E+ ++ P+ K + + R + H + +NQ + P
Sbjct: 460 ------LDEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTV--QRNQMLMTPTSA 511
Query: 150 ----VQAAPKEKSEQKKAKKAFQKRRLDKVRRKK----------EEKAADRLE------Q 189
+++ K + + K +++RL+ +RRK+ EE RLE +
Sbjct: 512 PRSVMKSFIKRNTPLRMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571
Query: 190 ELLRDTVKFGEVVLQPPELTAR--PQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLAR 247
E LR ++ E V Q E + Q+ D+ +++ R+ A+ +
Sbjct: 572 ERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERL----AEEKAKKKAAAKK 627
Query: 248 QRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQ 288
VE R++ +A R +Q++ L +KK E Q
Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQ 668
Score = 29.3 bits (64), Expect = 4.2
Identities = 21/109 (19%), Positives = 52/109 (47%), Gaps = 2/109 (1%)
Query: 2 AGAGRGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQ 61
A + A R Q RR + R++ + ++R L +E+++ + + Q E+
Sbjct: 674 AAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE--QERLQAER 731
Query: 62 EIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIA 110
E+ R + + +++++ + KK+K+ Q + L++E + + + A
Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAA 780
Score = 28.9 bits (63), Expect = 5.5
Identities = 45/196 (22%), Positives = 80/196 (40%), Gaps = 34/196 (17%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK 85
R+ + L K++ LR + K + + Q+ +E R +E R QE +
Sbjct: 654 RRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQE--RREQE--------R 703
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAI 145
R++ + R+ E+E R+ E + R QE + L L K Q
Sbjct: 704 REQERREQERQLAEQE---------------RRREQERLQAERELQEREKALRLQKEQLQ 748
Query: 146 RQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQP 205
R+ E + K+K EQ++ +R+L + + KK ++AA + L TV
Sbjct: 749 RELEEK---KKKEEQQR----LAERQLQEEQEKKAKEAAG--ASKALNVTVDVQSPACTS 799
Query: 206 PELTARPQRSVSKDQP 221
++T + R+ K P
Sbjct: 800 YQMTPQGHRAPPKINP 815
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 50.8 bits (120), Expect = 1e-06
Identities = 51/256 (19%), Positives = 118/256 (46%), Gaps = 26/256 (10%)
Query: 48 KKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI--SNKKRKKAAQVTFRKTLEKEAKGE 105
KK+ + +++D++ R+R+ +SR+ +N S + + R+ ++E
Sbjct: 22 KKRSRSRSRSRDKE----RVRKRSKSRESKRNRRRESRSRSRSTNTAVSRRERDRERASS 77
Query: 106 EPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKK 165
PD + F + + + ++E + + + IRQ E++ E+ ++ ++
Sbjct: 78 PPD-RIDIFGRTVSKRSSLDEKQKREEEEKKAEFERQRKIRQQEIEEKLIEEETARRVEE 136
Query: 166 AFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVV----------LQPPELTARPQRS 215
KR +++ ++K+E +E+E+LR + ++ + EL A Q++
Sbjct: 137 LVAKRVEEELEKRKDE-----IEREVLRRVEEAKRIMEKQLLEELERQRQAELAA--QKA 189
Query: 216 VSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQ--RIVEEERERAVQAYRALKQRQQQLH 273
+++ +R ++ R+L A LA + RIVEE+R+ + + ++RQ+Q
Sbjct: 190 REEEERAKREELERILEENNRKIAEAQAKLAEEQLRIVEEQRKIHEERMKLEQERQRQQK 249
Query: 274 GERPHLTSRKKPEPQL 289
E+ + + K P+L
Sbjct: 250 EEQKIILGKGKSRPKL 265
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 47.0 bits (110), Expect = 2e-05
Identities = 37/151 (24%), Positives = 77/151 (50%), Gaps = 11/151 (7%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQV----TFRKTLE 99
R KE+K+ K + + E++ R R+ R +E K +KRKK + T ++ E
Sbjct: 73 REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 100 KEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSE 159
+E K EE K ++RK E R +++ + + + + + E + KE+ E
Sbjct: 133 RERK-EERKREERKERERKKEEREKERERKERKKR------ERKQVGEKEEERKEKERKE 185
Query: 160 QKKAKKAFQKRRLDKVRRKKEEKAADRLEQE 190
+KK ++ ++R+ ++ R+++ E+ +R ++E
Sbjct: 186 RKKRERNRKERKKERERKERRERKKERKKKE 216
Score = 43.5 bits (101), Expect = 2e-04
Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 18/144 (12%)
Query: 47 EKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEE 106
+K++ + + K + E+E R RE R R+ K +++K+ + R+ ++ +GEE
Sbjct: 52 KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEE 111
Query: 107 PDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKA 166
+ K K+ +G + SK R+ + + +E+ E+++ K+
Sbjct: 112 KEKRKKKEKKERGRT------------------SKEGKERERKEERKREERKERERKKEE 153
Query: 167 FQKRRLDKVRRKKEEKAADRLEQE 190
+K R K R+K+E K E+E
Sbjct: 154 REKERERKERKKRERKQVGEKEEE 177
Score = 41.2 bits (95), Expect = 0.001
Identities = 51/243 (20%), Positives = 104/243 (42%), Gaps = 19/243 (7%)
Query: 47 EKKKVNC----KPKNQD--EQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEK 100
E + V+C KP Q + EI R REI ++ K S +K+++ + ++ EK
Sbjct: 16 ELQMVSCSHISKPCTQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREK 75
Query: 101 EAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQ 160
E K E K +RK E R ++E + K + + E KE E+
Sbjct: 76 ERKRERGK--KEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 161 KKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQ 220
++ ++ ++ R ++ R+K+E + ++ R+ + GE + E + ++ +++
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 221 PGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLT 280
R+ + R ++R +EER++ Q R R+++ G+R
Sbjct: 194 KERKKERER----------KERRERKKERKKKEERKKERQKDRQTNWREKE-RGKRERKE 242
Query: 281 SRK 283
+K
Sbjct: 243 RKK 245
Score = 34.7 bits (78), Expect = 0.10
Identities = 28/141 (19%), Positives = 65/141 (46%), Gaps = 11/141 (7%)
Query: 146 RQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQP 205
R+ E++ + K E++ +K ++ R + R +++E+ +R ++E K GE +
Sbjct: 41 REREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE------KKGERKKEE 94
Query: 206 PELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRAL 265
E R + +K+ + + + G S+ ++R +EER+R + R
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKE-----GKERERKEERKREERKERER 149
Query: 266 KQRQQQLHGERPHLTSRKKPE 286
K+ +++ ER R++ +
Sbjct: 150 KKEEREKERERKERKKRERKQ 170
Score = 34.3 bits (77), Expect = 0.13
Identities = 45/177 (25%), Positives = 83/177 (46%), Gaps = 36/177 (20%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
R+ R R++ G+++ + KEKK+ K E+E R+ R R+E K
Sbjct: 97 RKKRRREKENKEGEEKEKR----KKKEKKERGRTSKEGKERE-----RKEERKREERKER 147
Query: 81 ISNK-KRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFL 139
K +R+K + RK E++ GE+ + K K+RK R ++E
Sbjct: 148 ERKKEEREKERERKERKKRERKQVGEKEE--ERKEKERK--------ERKKRE------- 190
Query: 140 SKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVR------RKKEEKAADRLEQE 190
+N+ R+ E + KE+ E+KK +K ++R+ ++ + R+KE +R E++
Sbjct: 191 -RNRKERKKERER--KERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERK 244
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/314 (19%), Positives = 118/314 (37%), Gaps = 54/314 (17%)
Query: 8 AAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRL 67
A V VQ P P+ +++ ++ + R V+ K IP L
Sbjct: 235 AKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPL 294
Query: 68 REIMRSRQEMKNPISNKKR-------KKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGE 120
SR +P +K KK T +K E K E + A+ K+ G+
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGK 354
Query: 121 SDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE 180
+ Q + QAA K+ +++ +KK + +++ + KK+
Sbjct: 355 AS-----------------ETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQ 397
Query: 181 EKA-------------------------ADRLEQELLRDTVKFGEVVLQPPELTARPQRS 215
EK +R ++E+ ++K + + T ++
Sbjct: 398 EKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQE 457
Query: 216 VSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGE 275
+ K++ G+ S +L+ G + + ASL + ++ E+ +A + +K + QL G+
Sbjct: 458 IRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGK 517
Query: 276 RPHLTSRKKPEPQL 289
+ +KPEPQ+
Sbjct: 518 K-----EEKPEPQI 526
Score = 35.8 bits (81), Expect = 0.045
Identities = 56/271 (20%), Positives = 120/271 (44%), Gaps = 30/271 (11%)
Query: 12 RVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIM 71
++Q + +G+++V+ K + ++K+K K +++++ +
Sbjct: 157 KIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEE 216
Query: 72 RSRQEMKNPISNKKRKKAAQV-TFRKTLEKEAKGEEPD-IAVPKFKQRKGESDGAY---- 125
++++E+K K ++ AA+V +KT K + E+ + AV K +Q+ + Y
Sbjct: 217 KTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDI 276
Query: 126 -IHRMQQEAQHVLF---LSKNQAIRQPEVQAAPKEK-SEQKKAKKAF----QKRRLDKVR 176
+H + Q L QA R A +EK E+KKA+K +K+ + ++
Sbjct: 277 FVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK 336
Query: 177 RKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGG 236
+K E++ A +E+ ++ K E ++ A Q + KD+ S+ + P
Sbjct: 337 KKSEKETAIDVEK---KEPGKASETKQGTVKIAA--QAAAKKDEKKEDSKKTK---KPAE 388
Query: 237 VSQPLTASLARQRIVEEERERAVQAYRALKQ 267
V QP +E++E+ V+ ++ K+
Sbjct: 389 VEQPKGKK-------QEKKEKHVEPAKSPKK 412
Score = 34.3 bits (77), Expect = 0.13
Identities = 50/245 (20%), Positives = 107/245 (43%), Gaps = 36/245 (14%)
Query: 45 SKEKKKVNCKPKNQDEQEI---PFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKE 101
S E ++ + ++ D+ EI P R +EI + + E K+ K ++ + T +++
Sbjct: 115 SSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTE-------KQEKPERKIQTKVTHKEK 167
Query: 102 AKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQK 161
KG+E K R+ E + +++A H + K + +PE + KE+ + K
Sbjct: 168 EKGKE--------KVREKE-------KPEKKATHKEKIEKKE---KPETKTLAKEQKKAK 209
Query: 162 KAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQP 221
A+K+ +K + +V+ K+EK ++ + + +P E + + +VSK +
Sbjct: 210 TAEKSEEKTK-KEVKGGKQEKV-----KQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQ 263
Query: 222 GRRSQMLRMLLS--PGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHL 279
+ R ++ G +P + + E+ R A AL++++ + +
Sbjct: 264 KDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKV 323
Query: 280 TSRKK 284
TS K
Sbjct: 324 TSETK 328
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 44.3 bits (103), Expect = 1e-04
Identities = 55/242 (22%), Positives = 100/242 (41%), Gaps = 18/242 (7%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAK 103
R +E+++ + + +D R RE R RQ + +++R+K + E E +
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRE--RDRQREKERNRQKERERETERE 134
Query: 104 GEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKA 163
GE + R ++DG Q++A+ + Q R+ + Q + E+++
Sbjct: 135 GE---------RGRDRQTDGQRERERQRDAEKE---RERQTDRERQRQTERNRQKERERE 182
Query: 164 KKAFQKRRLDKVRRKKEEKAADR-LEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPG 222
K Q+RR + +R+KE K DR E+ R+ + E + T R + K +
Sbjct: 183 KNR-QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERE 241
Query: 223 RRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSR 282
R Q R S + R R + +R+R + R++Q ER T R
Sbjct: 242 REKQAERERASERETERDKERERERDR--DRDRDRRQKERERQTDRKRQRRTERDRETER 299
Query: 283 KK 284
K+
Sbjct: 300 KR 301
Score = 42.7 bits (99), Expect = 4e-04
Identities = 55/250 (22%), Positives = 105/250 (42%), Gaps = 19/250 (7%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEA- 102
R+++K++ + K Q E+E R RE R + + +++R++ + + ++E
Sbjct: 56 RNRQKERERRREKRQTERETD-RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERD 114
Query: 103 KGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKN-------QAIRQPEVQAAPK 155
+ E + K ++R+ E +G Q + Q ++ Q R+ + Q
Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174
Query: 156 EKSEQKKAKKAFQKRRLDKVRRKKEEKAADR-LEQELLRDTVKFGEVVLQPPELTARPQR 214
+ E+++ K Q+RR + +R+KE K DR E+ R+ + E + T R +
Sbjct: 175 RQKEREREKNR-QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERD 233
Query: 215 SVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHG 274
K + R Q R S R + E ER+R R K+R++Q
Sbjct: 234 RQRKTEREREKQAERERAS--------ERETERDKERERERDRDRDRDRRQKERERQTDR 285
Query: 275 ERPHLTSRKK 284
+R T R +
Sbjct: 286 KRQRRTERDR 295
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/264 (18%), Positives = 115/264 (43%), Gaps = 6/264 (2%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
+ R RQ + +QR + +E++ + +D Q R RE R ++ +
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQ 162
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
++++R++ + +K E+E K + + ++++ +++ + R ++ + ++
Sbjct: 163 TDRERQRQTERNRQKERERE-KNRQERRERERQREKENKTEDRHSERGRERERERETETE 221
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDK--VRRKKEEKAADRLEQELLRDTVKFG 199
+ RQ + + + K+E+++ K+A ++R ++ R K+ E+ DR R +
Sbjct: 222 TERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERER 281
Query: 200 EVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAV 259
+ + T R + + K + R + R + RQR E +RE+
Sbjct: 282 QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKER 341
Query: 260 QAYRALKQRQQQLHGERPHLTSRK 283
+ R +RQ ++ ER T R+
Sbjct: 342 ERKR---KRQTEMDRERNRQTGRE 362
Score = 37.0 bits (84), Expect = 0.020
Identities = 52/264 (19%), Positives = 105/264 (39%), Gaps = 24/264 (9%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R R R++ + ++R R +EK++ + +D Q R R+ R R+ +
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETER--- 133
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
+R + Q ++ E++ E K+R+ ++D + ++ Q K
Sbjct: 134 -EGERGRDRQTDGQRERERQRDAE---------KERERQTDRERQRQTERNRQKEREREK 183
Query: 142 N-QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGE 200
N Q R+ E Q + K+E + +++ ++ R + + E K E++ R T + E
Sbjct: 184 NRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTERERE 243
Query: 201 VVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQ 260
+ E +R +D+ R + + RQR E +RE
Sbjct: 244 ---KQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE-- 298
Query: 261 AYRALKQRQQQLHGERPHLTSRKK 284
++R++Q ER +RK+
Sbjct: 299 -----RKRERQRERERERERNRKR 317
Score = 33.1 bits (74), Expect = 0.29
Identities = 41/218 (18%), Positives = 88/218 (40%), Gaps = 31/218 (14%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMK--- 78
R R R++ + ++R R +E+++ + + ++ + R E+ R R
Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362
Query: 79 -NPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVL 137
+ ++R++ + + E+E + + D K ++R+ E D
Sbjct: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD--------------- 407
Query: 138 FLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADR-LEQELLRDTV 196
R+ E Q ++ E ++ ++ ++R K R + E+ DR ++ R T
Sbjct: 408 ----RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRST- 462
Query: 197 KFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSP 234
+ + PP TAR V + P R ++ +R SP
Sbjct: 463 ----LYVNPPPRTAR--SGVVQSDPNRPTRGIRWKSSP 494
Score = 31.2 bits (69), Expect = 1.1
Identities = 39/215 (18%), Positives = 91/215 (42%), Gaps = 39/215 (18%)
Query: 76 EMKNPISNKKRKKAAQVTFRKT----LEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQ 131
E+ P+ +R+ +Q + R+ K+A G++ + K ++R+ E + ++
Sbjct: 19 EVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREK-----RQTER 73
Query: 132 EAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQEL 191
E K + R+ + E+++ ++ ++R+ D+ R ++ EK +R ++E
Sbjct: 74 ETDR-----KRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNR-QKER 127
Query: 192 LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIV 251
R+T + GE R + G+R + + A R+R
Sbjct: 128 ERETEREGE-------------RGRDRQTDGQRER-----------ERQRDAEKERERQT 163
Query: 252 EEERERAVQAYRALKQRQQQLHGERPHLTSRKKPE 286
+ ER+R + R ++ +++ ER +++ E
Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKE 198
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 43.5 bits (101), Expect = 2e-04
Identities = 59/282 (20%), Positives = 114/282 (40%), Gaps = 19/282 (6%)
Query: 6 RGAAVSRVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPF 65
R A R + R A RQ+++ K+ ++ +EK+ + + ++E++
Sbjct: 308 RREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAA 367
Query: 66 RLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAY 125
R+ R+ +E K + +KR K + E + KGE+ ++K E
Sbjct: 368 EERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEK--------VEQKIEGKWVN 419
Query: 126 IHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAAD 185
+ Q++ L K + +VQ A +EK ++ K ++ + +K+++ KE K
Sbjct: 420 EKKAQEDKLQTAVLKKQGEEKGTKVQ-AKREKLQEDKPTFKKEEIKDEKIKKDKEPKE-- 476
Query: 186 RLEQELLRDTVK-FGEVVLQPPELTARPQRSVSK--DQPGRRSQMLRMLLSPGGVSQPLT 242
E + D K F EV Q E + +PG R+ + G Q +
Sbjct: 477 --EVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGGRASV--DTKEAEGAPQ-VE 531
Query: 243 ASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKK 284
A + + E + + LKQ+QQ+ E L +++
Sbjct: 532 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKRE 573
Score = 30.4 bits (67), Expect = 1.9
Identities = 55/270 (20%), Positives = 107/270 (39%), Gaps = 58/270 (21%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFR-----------LREIMRSRQEMKNPISNKKRKKAAQV 92
R E+ K K K ++E+E P R + E QE +S K Q+
Sbjct: 178 RDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKN----GQI 233
Query: 93 TFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQ--------A 144
+ + ++E + + D K + + + A R + EA+ + Q A
Sbjct: 234 SSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERA 293
Query: 145 IRQPEVQAAPKEK----SEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGE 200
+ E +AA +E+ +E+++ + +KR ++ +R KEE+ E++ +++
Sbjct: 294 RIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKE------ 347
Query: 201 VVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERA-V 259
E A +R K++ R A+ RQR EE E+A V
Sbjct: 348 -----EEKRAAEERQRIKEEEKR-------------------AAEERQRARAEEEEKAKV 383
Query: 260 QAYRALKQRQQQLHGERPHLTSRKKPEPQL 289
+ + KQ +++ H + +K E ++
Sbjct: 384 EEQKRNKQLEEKKHAMQETKIKGEKVEQKI 413
Score = 30.4 bits (67), Expect = 1.9
Identities = 43/212 (20%), Positives = 91/212 (42%), Gaps = 48/212 (22%)
Query: 28 QVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK-- 85
Q L KQ +++K +K KP + E+ ++++ ++E+K+ + KK
Sbjct: 429 QTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGF 488
Query: 86 -------------RKKAAQVTF-----RKTLE-KEAKGE---EPDIAVPKFKQRKGESDG 123
+ K + TF R +++ KEA+G E + + ++R+GE++
Sbjct: 489 TEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETES 548
Query: 124 AYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRK----- 178
+++Q+ Q E++ K++ E++K + ++ RRK
Sbjct: 549 EEFEKLKQKQQEAAL----------ELEELKKKREERRKVLEE------EEQRRKQEEAD 592
Query: 179 ---KEEKAADRLEQELLRDTVKFGEVVLQPPE 207
+EE+ RL++E+ R + E + PE
Sbjct: 593 RKLREEEEKRRLKEEIERRRAEAAEKRQKMPE 624
Score = 28.9 bits (63), Expect = 5.5
Identities = 36/191 (18%), Positives = 82/191 (42%), Gaps = 22/191 (11%)
Query: 14 QAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRS 73
Q P++ R+Q G + + ++K++ + + +E RE +++
Sbjct: 232 QISSEEPKQEEEREQ----GSDEISHHEKMEEEDKERAEAERARLEAEE-----RERIKA 282
Query: 74 RQEMKNPISNKK----RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQR-KGESDGAYIHR 128
Q+ K + K AAQ R+ E+ + E + + +QR K E A R
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEER 342
Query: 129 MQQEAQHVLFLSKNQAIRQPEVQAAP------KEKSEQKKAKKAFQKRRLDKVRRKKEEK 182
+ + + + Q I++ E +AA E+ E+ K ++ + ++L++ + +E
Sbjct: 343 QRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQET 402
Query: 183 --AADRLEQEL 191
+++EQ++
Sbjct: 403 KIKGEKVEQKI 413
>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
sapiens]
Length = 929
Score = 42.7 bits (99), Expect = 4e-04
Identities = 42/210 (20%), Positives = 94/210 (44%), Gaps = 23/210 (10%)
Query: 22 RARGRQQVQPLGKQRPAPWPG-LRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
+ + +++ + G++ PW L+ +E K K ++ + +L++ + +++ K+
Sbjct: 558 KVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHK 617
Query: 81 ISNKKRKKAAQVTFRKTLEK-EAKGEEP--------------DIAVPKFKQRKGESDGAY 125
K R+K + ++ EK + KG E ++A+P F A
Sbjct: 618 DKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAM 677
Query: 126 IHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAAD 185
+ + LF K + +++ E + KEK +KK +K +K+ ++ + K+E + +
Sbjct: 678 LPSLLPVLPEKLFEEKEK-VKEKEKKKDKKEK--KKKKEKEKEKKEKEREKEKREREKRE 734
Query: 186 RLEQELLRDTVKFGEVVLQP----PELTAR 211
+ +++ + +K V L P P LT R
Sbjct: 735 KEKEKHKHEKIKVEPVALAPSPVIPRLTLR 764
Score = 35.8 bits (81), Expect = 0.045
Identities = 43/211 (20%), Positives = 93/211 (44%), Gaps = 12/211 (5%)
Query: 66 RLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEA-KGEEPDIAVPKFKQRKGESDGA 124
+L + ++++K + K +KK Q + +K K +E D K K ++ +
Sbjct: 514 KLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETK 573
Query: 125 YIHR---MQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEE 181
Y + ++EA F K PK K + +K +K + K R+K +
Sbjct: 574 YPWKEFLKEEEADPYKFKIKEFE------DVDPKVKLKDGLVRKEKEKHKDKKKDREKGK 627
Query: 182 KAADRLEQELLRDTVKFGEVVLQPPELTARPQR-SVSKDQPGRRSQMLRMLLSPGGVSQP 240
K D+ E+E ++D + ++ P L P+ ++ P S++ ML S V P
Sbjct: 628 KDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPV-LP 686
Query: 241 LTASLARQRIVEEERERAVQAYRALKQRQQQ 271
++++ E+E+++ + + K+++++
Sbjct: 687 EKLFEEKEKVKEKEKKKDKKEKKKKKEKEKE 717
>gi|21735548 centrosomal protein 2 [Homo sapiens]
Length = 2442
Score = 42.4 bits (98), Expect = 5e-04
Identities = 49/225 (21%), Positives = 104/225 (46%), Gaps = 17/225 (7%)
Query: 70 IMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIH-R 128
+++ + +++ + + K + AQ ++ +E+E + + + Q++ E + A +
Sbjct: 1001 LLQDKMDLQKQVEDLKSQLVAQDDSQRLVEQEVQEKLRETQEYNRIQKELEREKASLTLS 1060
Query: 129 MQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLE 188
+ ++ Q +L L + +IRQ E+ A ++ E + +K +++ +R++ +EK AD L
Sbjct: 1061 LMEKEQRLLVLQEADSIRQQELSALRQDMQEAQGEQKEL-SAQMELLRQEVKEKEADFLA 1119
Query: 189 QE--LLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLA 246
QE LL + L+ +T + R+ Q + +Q+ L S L A A
Sbjct: 1120 QEAQLLEE--------LEASHITEQQLRASLWAQEAKAAQLQLRLRS---TESQLEALAA 1168
Query: 247 RQRIVEEERERAVQA--YRALKQRQQQLHGERPHLTSRKKPEPQL 289
Q+ + + +A A Y AL+Q + RP L+ P +
Sbjct: 1169 EQQPGNQAQAQAQLASLYSALQQALGSVCESRPELSGGGDSAPSV 1213
Score = 29.6 bits (65), Expect = 3.2
Identities = 14/49 (28%), Positives = 28/49 (57%)
Query: 62 EIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIA 110
E+ LR+I ++E++ +S + ++ A T + L +EAK +E +A
Sbjct: 677 ELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAKRQEEVLA 725
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 42.4 bits (98), Expect = 5e-04
Identities = 39/177 (22%), Positives = 79/177 (44%), Gaps = 8/177 (4%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R + R++ + ++R R K++KK K + E+E + RE R + K
Sbjct: 36 RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
KK KK + R E++ K E + + ++ K + R +++ + K
Sbjct: 96 KRKKEKKKRERKQRGRRERKKKKERKE----RERENKQRRERKRKKRRKKKRRKERKREK 151
Query: 142 NQAIRQPEVQAAPKEKSEQKKAK----KAFQKRRLDKVRRKKEEKAADRLEQELLRD 194
+ R+ + + KE+ E+K+ + + ++ R ++ RKKE K R ++E +D
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKD 208
Score = 42.0 bits (97), Expect = 6e-04
Identities = 40/173 (23%), Positives = 85/173 (49%), Gaps = 19/173 (10%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
+R RG+++ + K+R R KE++K + K ++ ++ R R+ + R+E +
Sbjct: 68 KRERGKERERKR-KEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERER- 125
Query: 81 ISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLS 140
NK+R++ + RK ++ + E + + K++K + + ++E +
Sbjct: 126 -ENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKE-------EREKKR----E 173
Query: 141 KNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLR 193
+N+ R+ E + KE+ E+KK +K K R K RKK+ K + + ++ R
Sbjct: 174 RNRKERKKERER--KERRERKKERK---KERRKKKERKKDRKTDRQTDSQVFR 221
Score = 33.9 bits (76), Expect = 0.17
Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 7/131 (5%)
Query: 155 KEKSEQKKAKKAFQKRRLDKVRRK-KEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQ 213
KE+ ++K ++ +K R +K RRK K+EK +Q R+ K E + E R +
Sbjct: 73 KERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRE 132
Query: 214 RSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLH 273
R K + +R + + G R++ +EERE+ + R ++++++
Sbjct: 133 RKRKKRRKKKRRKERKREKERG------KRERKRKKRKKEEREKKRERNRKERKKERERK 186
Query: 274 GERPHLTSRKK 284
R RKK
Sbjct: 187 ERRERKKERKK 197
Score = 29.6 bits (65), Expect = 3.2
Identities = 33/154 (21%), Positives = 65/154 (42%), Gaps = 18/154 (11%)
Query: 139 LSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKF 198
+SK R+ E + +E+ ++K+ ++ +KR K +KK +K E+E R +
Sbjct: 25 ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84
Query: 199 GEVVLQPPELTARPQRSVSKD--QPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERE 256
+ E R + ++ Q GRR + + R+R ++ RE
Sbjct: 85 QRKERREKERRKRKKEKKKRERKQRGRRERKKK------------KERKERERENKQRRE 132
Query: 257 RAVQAYRALKQRQQQL----HGERPHLTSRKKPE 286
R + R K+R+++ G+R ++K E
Sbjct: 133 RKRKKRRKKKRRKERKREKERGKRERKRKKRKKE 166
Score = 28.9 bits (63), Expect = 5.5
Identities = 29/108 (26%), Positives = 51/108 (47%), Gaps = 8/108 (7%)
Query: 12 RVQAGPGSPRRARGRQQVQPLGKQRPAPWPGLRSKEKK-KVNCKPKNQDEQEIPFRLREI 70
R Q G ++ + R++ + KQR R K+K+ K + K + ++E + R+
Sbjct: 106 RKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRK- 164
Query: 71 MRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRK 118
+ +E K + K+RKK + R+ +KE K E K K+RK
Sbjct: 165 -KEEREKKRERNRKERKKERERKERRERKKERKKER-----RKKKERK 206
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/199 (19%), Positives = 91/199 (45%), Gaps = 8/199 (4%)
Query: 26 RQQVQPLGKQRPAPW---PGLRSKEKKKVNCKPKN-QDEQEIPFRLREIMRSRQEMKNPI 81
R+Q + + KQ W LR +E K + K + E+ + + +E+ +E++
Sbjct: 282 REQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK 341
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
+++++ Q K E+E K E + + + ++R E + +M+++ Q + +
Sbjct: 342 ELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE----KQMREQEQKMRDQEE 397
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEV 201
+ ++ + EQ+K + +K R +K +++E+K D+ E+ + ++ E
Sbjct: 398 RMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREK 457
Query: 202 VLQPPELTARPQRSVSKDQ 220
++ E T R Q + Q
Sbjct: 458 KMREEEETMREQEEKMQKQ 476
Score = 34.7 bits (78), Expect = 0.10
Identities = 42/254 (16%), Positives = 111/254 (43%), Gaps = 11/254 (4%)
Query: 43 LRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEA 102
++ +EKK + + K Q+E+ I R +++ + M+ +K +K + + + ++
Sbjct: 432 MQEQEKKTRDQEEKMQEEERIREREKKMREEEETMRE--QEEKMQKQEENMWEQEEKEWQ 489
Query: 103 KGEEPDIAVPKFKQRKGESDGAYIHRMQQEA--QHVLFLSKNQAIRQPEVQAAP------ 154
+ P+ ++Q K + I +++ Q ++ + + RQ +++
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 155 KEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQR 214
+EK ++ K Q+ R++K +++E+K D+ E+ + ++ E ++ E R Q
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 215 SVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHG 274
++Q + + + Q + Q E+E + + L +++++L
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL-W 668
Query: 275 ERPHLTSRKKPEPQ 288
E + ++K + Q
Sbjct: 669 EHEKMQEQEKMQEQ 682
Score = 33.9 bits (76), Expect = 0.17
Identities = 43/262 (16%), Positives = 113/262 (43%), Gaps = 25/262 (9%)
Query: 27 QQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI-SNKK 85
+Q + + +Q W R E+K+ + + EQE QE + I +K
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQE----------KMQEQEEKIWEQEK 691
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAI 145
+K Q +KT ++E EE + + K R+ E + R Q+E + + +
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEE----MMREQEEKMQ----EQEEKM 743
Query: 146 RQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQP 205
++ E + +E+ ++ +K ++++RL + + K E + ++++ K + Q
Sbjct: 744 QEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRD---QE 800
Query: 206 PELTARPQRSVSKDQP--GRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAY- 262
++ + ++ +++ G+ +M G + + + EE+ E +Q
Sbjct: 801 EKMRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQE 860
Query: 263 RALKQRQQQLHGERPHLTSRKK 284
++++++++ G+ + +++
Sbjct: 861 EKMREQEEKMRGQEEKMREQEE 882
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 41.2 bits (95), Expect = 0.001
Identities = 38/149 (25%), Positives = 73/149 (48%), Gaps = 10/149 (6%)
Query: 135 HVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRD 194
H L++ + R+P+ + K++ ++ K Q R KK+ + A++ ++++ R+
Sbjct: 288 HELYMRR----RKPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIERE 343
Query: 195 TVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQR-IVEE 253
+ E + Q E T + Q+ + ++ RR+ L +Q LA++R EE
Sbjct: 344 KEELMERLKQIEEQTKKAQQEL--EEQTRRALELEQERKR---AQSEAEKLAKERQEAEE 398
Query: 254 ERERAVQAYRALKQRQQQLHGERPHLTSR 282
+E +QA R K+ Q+QL E LT+R
Sbjct: 399 AKEALLQASRDQKKTQEQLALEMAELTAR 427
Score = 40.8 bits (94), Expect = 0.001
Identities = 49/222 (22%), Positives = 97/222 (43%), Gaps = 15/222 (6%)
Query: 54 KPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPK 113
KP + Q++ + RE +Q + + N+K+K+ EKE E + + +
Sbjct: 296 KPDTIEVQQMKAQAREEKHQKQMERAMLENEKKKRE-----MAEKEKEKIEREKEELMER 350
Query: 114 FKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLD 173
KQ + ++ A ++++ + L L + + Q E + KE+ E ++AK+A + D
Sbjct: 351 LKQIEEQTKKAQ-QELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRD 409
Query: 174 KVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTA----RPQRSVSKDQPGRRSQMLR 229
++K +E+ A LE L + E+ Q E A + + V +D R++ L+
Sbjct: 410 --QKKTQEQLA--LEMAELTARISQLEMARQKKESEAVEWQQKAQMVQEDLEKTRAE-LK 464
Query: 230 MLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQ 271
+S V++P Q E ++A K R ++
Sbjct: 465 TAMSTPHVAEPAENEQDEQDENGAEASADLRADAMAKDRSEE 506
>gi|146260271 hypothetical protein LOC129881 [Homo sapiens]
Length = 552
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/209 (17%), Positives = 96/209 (45%), Gaps = 35/209 (16%)
Query: 81 ISNKKRKKAAQVTFRKTLEKEAKGEEPDIAV---PKFKQRKGESDGAYIHRMQQEAQHVL 137
+S +++ AQ+ FRK+ K K E + + FK+ + +++ + R+ H+
Sbjct: 161 LSRVMKERDAQIEFRKSKIKSDKKWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHL- 219
Query: 138 FLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVR-RKKEEKAADRLEQELLR--D 194
+ I++ E + ++K E+K A++ ++ L ++ RKK EK + + + R +
Sbjct: 220 -----KQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFLE 274
Query: 195 TVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEE 254
++ ++ ++V + Q + +R + A++R+++
Sbjct: 275 HMQDKHII-----------KAVEQQQQEEEDEKMRKFIK------------AKKRLIQMG 311
Query: 255 RERAVQAYRALKQRQQQLHGERPHLTSRK 283
+E+ + +R +++R++++H L K
Sbjct: 312 KEKEAETHRLMEKRRERIHNFLSELLKEK 340
>gi|193788632 DnaJ (Hsp40) homolog, subfamily C, member 2 isoform 2
[Homo sapiens]
Length = 568
Score = 40.8 bits (94), Expect = 0.001
Identities = 45/167 (26%), Positives = 77/167 (46%), Gaps = 34/167 (20%)
Query: 43 LRSKEKKKVNCKPKN------------QDEQEIPFRLREIMRSRQEMKNPISNKKRKKAA 90
L +EK+K C+ + Q ++E R+R ++ + I K ++ A
Sbjct: 230 LDEEEKEKAECRDERRWIEKQNRATRAQRKKEEMNRIRTLVDNAYSCDPRIKKFKEEEKA 289
Query: 91 QVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEV 150
+ K + EAK +E + K KQR+ E + A + + ++E + +RQ +
Sbjct: 290 KKEAEKKAKAEAKRKEQEA---KEKQRQAELEAARLAKEKEEEE----------VRQ-QA 335
Query: 151 QAAPKEKSEQKKA-KKAFQKRR-------LDKVRRKKEEKAADRLEQ 189
A KEK QKKA KK QK R +++ RK++E+A R+ Q
Sbjct: 336 LLAKKEKDIQKKAIKKERQKLRNSCKIEEINEQIRKEKEEAEARMRQ 382
Score = 31.2 bits (69), Expect = 1.1
Identities = 25/104 (24%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 128 RMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRL 187
R ++E + L N P + K+ E++KAKK +K+ + +RK++E +
Sbjct: 258 RKKEEMNRIRTLVDNAYSCDPRI----KKFKEEEKAKKEAEKKAKAEAKRKEQEAKEKQR 313
Query: 188 EQEL--LRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLR 229
+ EL R + E ++ L A+ ++ + K + Q LR
Sbjct: 314 QAELEAARLAKEKEEEEVRQQALLAKKEKDIQKKAIKKERQKLR 357
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 40.8 bits (94), Expect = 0.001
Identities = 55/283 (19%), Positives = 117/283 (41%), Gaps = 32/283 (11%)
Query: 27 QQVQPLGKQ----RPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPIS 82
QQ P +Q RP P+P + + K + + + EI + + R+E + +
Sbjct: 415 QQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAVERARKRREEEERRME 474
Query: 83 NKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKN 142
+++ A+ R + ++P + ++R+ E + +QE + K+
Sbjct: 475 EQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKD 534
Query: 143 QAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE-EKAADRL-----------EQE 190
+ +Q + + KE+ +Q++ +K ++ + ++ R+KE EK ++ E+E
Sbjct: 535 RERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKERE 594
Query: 191 LLRDTVKFGEVVLQPPELTARPQRSVSKD-------QPGRRSQMLRMLL----SPGGVSQ 239
L + ++ E L+P + S +K+ Q RS+ + P SQ
Sbjct: 595 KLEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQ 654
Query: 240 PLTASLAR-----QRIVEEERERAVQAYRALKQRQQQLHGERP 277
P A L+ Q+ + +R + + + +QQQ G P
Sbjct: 655 PRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQGVLP 697
Score = 36.2 bits (82), Expect = 0.034
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 24/165 (14%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R R ++ + + +QR A + +K+ K +EI R RE R R++
Sbjct: 463 RKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKE 522
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
++R+K + + EKE + E+ + KQR+ E + R Q+
Sbjct: 523 QEQEREKEREKDRERQQEKEKELEK-----EQEKQREMEKE-----RKQE---------- 562
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADR 186
++ E++ +++ E +K K+ ++ L+K R K EEK R
Sbjct: 563 ----KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPR 603
Score = 28.5 bits (62), Expect = 7.2
Identities = 49/232 (21%), Positives = 91/232 (39%), Gaps = 36/232 (15%)
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQR-------------KGESDGAYIHR 128
S RK++ T + + + EP +PK R K + +G +I
Sbjct: 917 SQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDSKEPIERPEEKPKKEG-FIRS 975
Query: 129 MQQEAQHVLFLSKNQ--------AIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE 180
+ ++ SK++ + R+ EV P +S K + + R++KE
Sbjct: 976 SEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPIKKPVLRDMKEEREQRKEKE 1035
Query: 181 EKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQP 240
+ A+++ ++++ K + L PP +P + QP Q + + P P
Sbjct: 1036 GEKAEKVTEKVVVKPEKTEKKDLPPPPPPPQPPAPI---QP----QSVPPPIQPEAEKFP 1088
Query: 241 L--TASLARQRIVEEERE----RAVQAYRALKQRQQQLHGERPHLTSRKKPE 286
TA+LA++ + E+ VQ A+K QQ P + K+PE
Sbjct: 1089 STETATLAQKPSQDTEKPLEPVSTVQVEPAVKTVNQQTMA-APVVKEEKQPE 1139
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 40.4 bits (93), Expect = 0.002
Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 11/165 (6%)
Query: 26 RQQVQPLGKQRPAPW---PGLRSKEKK------KVNCKPKNQDEQEIPFRLREIMRSRQE 76
++Q + +G+Q W ++ +E+K K+ + K EQE R +E M QE
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 466
Query: 77 MKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHV 136
K + ++ K Q + E++ + +E I + K R+ E M QE +
Sbjct: 467 EK--MGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 524
Query: 137 LFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEE 181
++ + + Q E +EK +++ K Q+ RL + K +E
Sbjct: 525 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 37.7 bits (86), Expect = 0.012
Identities = 45/234 (19%), Positives = 101/234 (43%), Gaps = 8/234 (3%)
Query: 46 KEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFR--KTLEKEAK 103
+E+K + K Q+++E E MR ++EM K R++ + + K E E K
Sbjct: 293 QEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEK 352
Query: 104 -GEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKK 162
E+ I + K+++ E R +QEA+ + + IR+ E + +E+ Q++
Sbjct: 353 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAK---MWRQEEKIREQEEKIREQEEMMQEQ 409
Query: 163 AKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPG 222
+K ++ +K+ ++EE + + ++ E ++ E R Q + ++Q
Sbjct: 410 EEKMGEQE--EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467
Query: 223 RRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGER 276
+ + + Q + RQ E+E+ ++ + Q+++ E+
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 521
Score = 34.3 bits (77), Expect = 0.13
Identities = 54/271 (19%), Positives = 111/271 (40%), Gaps = 20/271 (7%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
++ + + ++ L K+R A L K KN QE +L+ + + E++
Sbjct: 175 QKKKADRYIEELTKERDALSLELYRNTITDEELKEKNAKLQE---KLQLVESEKSEIQLN 231
Query: 81 ISNKKRK--KAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLF 138
+ KRK +A + ++ L+ EA ++ K + + +R+ Q+ + ++
Sbjct: 232 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 291
Query: 139 LSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKF 198
+ + + E +EK +++ K RR +++ +KEEK R E+ + K
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKM----RRQEEMMWEKEEKMR-RQEEMMWEKEEKI 346
Query: 199 GEVVLQPPELTA-RPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERER 257
E+ + E R Q +++ R Q R Q A + RQ E+E
Sbjct: 347 RELEEKMHEQEKIREQEEKRQEEEKIREQEKR---------QEQEAKMWRQEEKIREQEE 397
Query: 258 AVQAYRALKQRQQQLHGERPHLTSRKKPEPQ 288
++ + Q Q++ GE+ ++ E Q
Sbjct: 398 KIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Score = 33.5 bits (75), Expect = 0.22
Identities = 38/200 (19%), Positives = 84/200 (42%), Gaps = 17/200 (8%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFR-----------LREIMRSRQEMKNPISNKKRKKAAQV 92
+ +E++K+ + K Q+++ +R +RE QE + + ++ K Q
Sbjct: 365 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQE 424
Query: 93 TFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQA 152
+ E++ + +E I + K R+ E M QE + + + + Q
Sbjct: 425 EEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE----QE 480
Query: 153 APKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLE--QELLRDTVKFGEVVLQPPELTA 210
A ++ E+K ++ + R +K R++EEK ++ E QE + E + + E
Sbjct: 481 AKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ 540
Query: 211 RPQRSVSKDQPGRRSQMLRM 230
+ + + + R Q +R+
Sbjct: 541 EQEEKMRRQEEKMREQEVRL 560
Score = 32.7 bits (73), Expect = 0.38
Identities = 36/213 (16%), Positives = 93/213 (43%), Gaps = 23/213 (10%)
Query: 75 QEMKNPISNKKRKKAAQVTFR---KTLEKEAKGEEPDIAVPKFKQR-KGESDGAYIHRMQ 130
Q +N + N+ ++ + +R K E+E K +E + + + +++ + + + + +
Sbjct: 272 QVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEK 331
Query: 131 QEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQE 190
Q + K + IR+ E + +EK +++ K+ +++ ++ +R+++E R E++
Sbjct: 332 MRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEK 391
Query: 191 LLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQ-- 248
+ K R Q + ++Q + + + Q + RQ
Sbjct: 392 IREQEEKI------------REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEE 439
Query: 249 RIVEEER-----ERAVQAYRALKQRQQQLHGER 276
+I E+E+ E ++ + Q Q++ GE+
Sbjct: 440 KIREQEKKIREQEEKIREQEEMMQEQEEKMGEQ 472
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 40.4 bits (93), Expect = 0.002
Identities = 50/270 (18%), Positives = 116/270 (42%), Gaps = 22/270 (8%)
Query: 19 SPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMK 78
S R GR + K R + R +K+ K +++ R ++ RS+ K
Sbjct: 300 SNERKGGRSRSHTRSKSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 356
Query: 79 NPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLF 138
+++R+K+ + + K+ + + + K K R+ E + ++E +
Sbjct: 357 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE----REKEREKEKERG 412
Query: 139 LSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQEL--LRDTV 196
+K++ + + + KEK +++ +K +K R DK + K+++K +R + + +
Sbjct: 413 KNKDRDKEREKDREKDKEKDREREREKEHEKDR-DKEKEKEQDKEKEREKDRSKEIDEKR 471
Query: 197 KFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERE 256
K + PP +RS S + RR + S+ + S + ++ +
Sbjct: 472 KKDKKSRTPPRSYNASRRSRSSSRERRRRR-----------SRSSSRSPRTSKTIKRKSS 520
Query: 257 RAVQAYRALKQRQQQLHGERPHLTSRKKPE 286
R+ + R+ ++ ++ ER H++ R++ E
Sbjct: 521 RS-PSPRSRNKKDKKREKERDHISERRERE 549
Score = 39.3 bits (90), Expect = 0.004
Identities = 41/200 (20%), Positives = 81/200 (40%), Gaps = 12/200 (6%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R + R++ + GK + R KE++K K K +D + + E R +++ K
Sbjct: 401 REKEREKEKERGKNKD------RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
K+R+K + +K+ K P P+ S + R ++ ++ +
Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRERRRRRSRSSSRSPR 510
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELL--RDTVKFG 199
+ + +P +S KK KK ++R RR++E + R ++ ++
Sbjct: 511 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 570
Query: 200 EVVLQPPELTARPQRSVSKD 219
L+ E P SVSK+
Sbjct: 571 STSLKEKEHNKEPDSSVSKE 590
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 40.4 bits (93), Expect = 0.002
Identities = 50/270 (18%), Positives = 116/270 (42%), Gaps = 22/270 (8%)
Query: 19 SPRRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMK 78
S R GR + K R + R +K+ K +++ R ++ RS+ K
Sbjct: 184 SNERKGGRSRSHTRSKSRSSSKSHSR---RKRSQSKHRSRSHNRSRSRQKDRRRSKSPHK 240
Query: 79 NPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLF 138
+++R+K+ + + K+ + + + K K R+ E + ++E +
Sbjct: 241 KRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERE----REKEREKEKERG 296
Query: 139 LSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQEL--LRDTV 196
+K++ + + + KEK +++ +K +K R DK + K+++K +R + + +
Sbjct: 297 KNKDRDKEREKDREKDKEKDREREREKEHEKDR-DKEKEKEQDKEKEREKDRSKEIDEKR 355
Query: 197 KFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERE 256
K + PP +RS S + RR + S+ + S + ++ +
Sbjct: 356 KKDKKSRTPPRSYNASRRSRSSSRERRRRR-----------SRSSSRSPRTSKTIKRKSS 404
Query: 257 RAVQAYRALKQRQQQLHGERPHLTSRKKPE 286
R+ + R+ ++ ++ ER H++ R++ E
Sbjct: 405 RS-PSPRSRNKKDKKREKERDHISERRERE 433
Score = 39.3 bits (90), Expect = 0.004
Identities = 41/200 (20%), Positives = 81/200 (40%), Gaps = 12/200 (6%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R + R++ + GK + R KE++K K K +D + + E R +++ K
Sbjct: 285 REKEREKEKERGKNKD------RDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
K+R+K + +K+ K P P+ S + R ++ ++ +
Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTP----PRSYNASRRSRSSSRERRRRRSRSSSRSPR 394
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELL--RDTVKFG 199
+ + +P +S KK KK ++R RR++E + R ++ ++
Sbjct: 395 TSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKN 454
Query: 200 EVVLQPPELTARPQRSVSKD 219
L+ E P SVSK+
Sbjct: 455 STSLKEKEHNKEPDSSVSKE 474
>gi|22758136 MAP7 domain containing 2 [Homo sapiens]
Length = 732
Score = 40.4 bits (93), Expect = 0.002
Identities = 45/185 (24%), Positives = 82/185 (44%), Gaps = 35/185 (18%)
Query: 47 EKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEE 106
EK++ K Q+EQE + + R+E+K +KA + R LE+EA+ +E
Sbjct: 406 EKRRQARLQKEQEEQERVEKEEQDRLEREELK--------RKAEEERLR--LEEEARKQE 455
Query: 107 PDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKA 166
+ + ++ K + +G + +EA+ R+ E + KEK EQ+K +KA
Sbjct: 456 EERK--RQEEEKKKQEGEEKRKAGEEAK-----------RKAEEELLLKEKQEQEKQEKA 502
Query: 167 FQKRRLDKVRRKKEEKAAD----------RLEQELLRDTVKFGEVVLQPPELTARPQRSV 216
+++ + K E A ++EQE L + E++ + + PQ V
Sbjct: 503 MIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVPPQ--V 560
Query: 217 SKDQP 221
K+ P
Sbjct: 561 KKEDP 565
Score = 31.2 bits (69), Expect = 1.1
Identities = 50/221 (22%), Positives = 91/221 (41%), Gaps = 27/221 (12%)
Query: 64 PFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDG 123
P + R S Q+M K K+ + TL ++A G + + A+ K K S+
Sbjct: 316 PVKYRLPALSGQDMPK---RKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASE- 371
Query: 124 AYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKA 183
+ +A++ L K A +AA ++++A+ QK + ++ R +KEE+
Sbjct: 372 KHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQAR--LQKEQEEQERVEKEEQ- 428
Query: 184 ADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTA 243
DRLE+E L+ + E R + K + R+ Q G
Sbjct: 429 -DRLEREELKRKAE---------EERLRLEEEARKQEEERKRQEEEKKKQEG-------- 470
Query: 244 SLARQRIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKK 284
+R EE +R + LK++Q+Q E+ + +K+
Sbjct: 471 --EEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKE 509
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/119 (26%), Positives = 58/119 (48%), Gaps = 11/119 (9%)
Query: 155 KEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQ- 213
+E+ EQ++ ++A ++ L ++++ +EEK E ELL++ + E +LQ E R Q
Sbjct: 330 REQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQH 389
Query: 214 RSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQL 272
R + + G+ + Q + A + EEE R Q + L++ QQ+L
Sbjct: 390 RELQQALEGQLRE----------AEQARASMQAEMELKEEEAARQRQRIKELEEMQQRL 438
Score = 33.5 bits (75), Expect = 0.22
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 21/174 (12%)
Query: 58 QDEQEIPFRLREIMRSRQEMKNPI--SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFK 115
Q+E+E + E+++ Q + ++R+++ ++ LE + + E A + +
Sbjct: 354 QEEKERKLQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAE 413
Query: 116 QRKGESDGAY-------IHRMQQEAQHVLFLS-------KNQAIRQPEVQAAPKEKSEQK 161
E + A + MQQ Q L L ++ I Q + +EK +Q
Sbjct: 414 MELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRIAQTRLLEEEEEKLKQL 473
Query: 162 KAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRS 215
K Q+R +++ +++KEE L+QE+ + + + Q E+ QR+
Sbjct: 474 MQLKEEQERYIERAQQEKEE-----LQQEMAQQSRSLQQAQQQLEEVRQNRQRA 522
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 40.0 bits (92), Expect = 0.002
Identities = 55/282 (19%), Positives = 112/282 (39%), Gaps = 47/282 (16%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPK-------NQDEQEIPFRLREIMRS 73
++ + R ++ G+ L+S++ +K N K K ++ + F+++ + +
Sbjct: 172 KKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQK 231
Query: 74 RQEMKNPISNKKRKKAAQVTFRKTLEKEA-KGEEPDIAVPKFKQRKGES---------DG 123
+ E K +K++ + RK EKE + + D + K QRK E D
Sbjct: 232 KAEKKE--RERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDT 289
Query: 124 AYIHRMQQEAQHVLFLS-------KNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVR 176
I +++A+ K + ++ + + KEK ++K KA K + +
Sbjct: 290 GVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALA 349
Query: 177 RKKEEKAADRLEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLR------- 229
+ KEE+ + E+E ++ E + E + +R K + R + L+
Sbjct: 350 KLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLT 409
Query: 230 --------------MLLSPGGVSQPLTASLARQRIVEEERER 257
LL GV P SL ++R + E+++R
Sbjct: 410 KSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 39.7 bits (91), Expect = 0.003
Identities = 50/267 (18%), Positives = 114/267 (42%), Gaps = 30/267 (11%)
Query: 21 RRARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNP 80
RR R R++ + +++ R +++ + K +++D R RE R R ++
Sbjct: 322 RREREREREREREREKEKERERERERDRDRDRTKERDRD------RDRERDRDRDRERSS 375
Query: 81 ISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLS 140
NK R ++ + + + E+E + E ++R+ E + ++E +
Sbjct: 376 DRNKDRSRSREKSRDRERERERERE---------RERERERERERERERERERERERERE 426
Query: 141 KNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGE 200
K+ K++ ++ + A+++R+L++ R+KE +RL+ +R+ K E
Sbjct: 427 KD------------KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTRE 474
Query: 201 VVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQ 260
+ E +R ++K+ R + L + S ++R+ + E+E
Sbjct: 475 YE-KEAEREEERRREMAKEAK-RLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEAD 532
Query: 261 AYRALKQRQQQLHGERPHLTSRKKPEP 287
R K+ +++L R L + P+P
Sbjct: 533 E-RDRKREKEELEEIRQRLLAEGHPDP 558
Score = 33.9 bits (76), Expect = 0.17
Identities = 43/210 (20%), Positives = 87/210 (41%), Gaps = 20/210 (9%)
Query: 22 RARGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R R R++ K R R +E+++ + + ++ + R RE R R+ +
Sbjct: 367 RDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERERE 426
Query: 82 SNKKRKKAA--------QVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEA 133
+KKR + + RK EKEA +E + ++ R+ + Y ++E
Sbjct: 427 KDKKRDREEDEEDAYERRKLERKLREKEAAYQE---RLKNWEIRERKKTREYEKEAEREE 483
Query: 134 QHVLFLSKNQAIRQPEVQAAPKEKSEQKKAK-KAFQKRRLDKVR--------RKKEEKAA 184
+ ++K + ++ ++ + K + A QKR D+ + RK+E++
Sbjct: 484 ERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL 543
Query: 185 DRLEQELLRDTVKFGEVVLQPPELTARPQR 214
+ + Q LL + + LQ E A +R
Sbjct: 544 EEIRQRLLAEGHPDPDAELQRMEQEAERRR 573
Score = 31.6 bits (70), Expect = 0.85
Identities = 40/163 (24%), Positives = 71/163 (43%), Gaps = 43/163 (26%)
Query: 46 KEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK---------RKKAAQVTFRK 96
+E+KK K + +E R RE+ + + +K + + R A Q R
Sbjct: 467 RERKKTREYEKEAEREEE--RRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRD 524
Query: 97 TLEKEAKGEEPDIAVPK-----FKQR---KGESD-GAYIHRMQQEAQHVLFLSKNQAIRQ 147
EKE + +E D K +QR +G D A + RM+QEA+ RQ
Sbjct: 525 R-EKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR---------RQ 574
Query: 148 PEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQE 190
P+++ P+ + E+++ +++KEEK + +E+E
Sbjct: 575 PQIKQEPESEEEEEE-------------KQEKEEKREEPMEEE 604
Score = 30.4 bits (67), Expect = 1.9
Identities = 33/146 (22%), Positives = 65/146 (44%), Gaps = 9/146 (6%)
Query: 139 LSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKF 198
L + + ++ E Q KE+ E+++ ++ ++RR + R++E + E+E R+ +
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRD 350
Query: 199 GEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERA 258
+ + E R +D+ RS S+ S R+R E ERER
Sbjct: 351 RD---RTKERDRDRDRERDRDRDRERSSDRNK-----DRSRSREKSRDRERERERERERE 402
Query: 259 VQAYRALKQRQQQLHGERPHLTSRKK 284
+ R ++R+++ ER R+K
Sbjct: 403 RERERE-REREREREREREREREREK 427
>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
isoform 2 [Homo sapiens]
Length = 1320
Score = 39.7 bits (91), Expect = 0.003
Identities = 53/226 (23%), Positives = 106/226 (46%), Gaps = 50/226 (22%)
Query: 68 REIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIH 127
R+ +R +QE NK+R +A + ++ L+++ E+ + +R+
Sbjct: 354 RDFLRLQQE------NKERSEALRR--QQLLQEQQLREQEEYKRQLLAERQ--------K 397
Query: 128 RMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKV-RRKKEEKAADR 186
R++Q+ + L + Q + E +A +++ EQ++ ++ +KRRL+++ RR+KEE+ R
Sbjct: 398 RIEQQKEQRRRLEEQQ---RREREARRQQEREQRRREQE-EKRRLEELERRRKEEEERRR 453
Query: 187 LEQELLRDTVKFGEVVLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLA 246
E+E +R V ++Q R Q+ + Q L L
Sbjct: 454 AEEE----------------------KRRVEREQEYIRRQLEEEQRHLEVLQQQL---LQ 488
Query: 247 RQRIVEEERERAVQAYRALKQRQQQLHGERPHLTS----RKKPEPQ 288
Q ++ E R R ++ +R ++ Q+QL E+ +L S ++P PQ
Sbjct: 489 EQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQ 534
Score = 32.0 bits (71), Expect = 0.65
Identities = 30/138 (21%), Positives = 62/138 (44%), Gaps = 15/138 (10%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSR---QEMKNPISNKKRKKAAQVTFRKTLEK 100
R +E ++ + + + EQE RL E+ R R +E + K+R + Q R+ LE+
Sbjct: 415 REREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEE 474
Query: 101 EAK----------GEEPDIAVPKFKQRKGESDGAYIHR-MQQEAQHVLFLSKNQAIRQPE 149
E + E+ + ++++ + + R +QQE ++L L + P+
Sbjct: 475 EQRHLEVLQQQLLQEQAMLLECRWREMEEHRQAERLQRQLQQEQAYLLSLQHDHRRPHPQ 534
Query: 150 VQAAPKEKSEQKKAKKAF 167
P +Q+++K +F
Sbjct: 535 HSQQP-PPPQQERSKPSF 551
Score = 31.2 bits (69), Expect = 1.1
Identities = 34/160 (21%), Positives = 71/160 (44%), Gaps = 16/160 (10%)
Query: 140 SKNQAIRQPEVQAAPKEKSEQKKAKKAF---QKRRLDKVRRKKEEKAADRLEQELLRDTV 196
S Q ++ P ++ P E+ + + K +K+R +K + E ++ E+E+
Sbjct: 279 STEQLLKHPFIRDQPNERQVRIQLKDHIDRTRKKRGEKDETEYEYSGSEEEEEEVPEQEG 338
Query: 197 KFGEVVLQPPELTAR------PQRSVSKDQPGRRSQML--RMLLSPGGVSQPLTASLARQ 248
+ +V P E T R Q + + + RR Q+L + L + L A RQ
Sbjct: 339 EPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAE--RQ 396
Query: 249 RIVEEERERAVQAYRALKQRQQQLHGERPHLTSRKKPEPQ 288
+ +E+++E Q R +Q++++ R +++ E +
Sbjct: 397 KRIEQQKE---QRRRLEEQQRREREARRQQEREQRRREQE 433
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 39.3 bits (90), Expect = 0.004
Identities = 35/245 (14%), Positives = 116/245 (47%), Gaps = 5/245 (2%)
Query: 44 RSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFRKTLEKEAK 103
+ +E++K+ + K Q+++ +R E +R ++E K ++ ++ ++ + +E K
Sbjct: 398 KRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEK 457
Query: 104 GEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSEQKKA 163
+E + + + +++ E + + + + Q + + + RQ E +EK +++
Sbjct: 458 RQEQE-EMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEE 516
Query: 164 KKAFQKRRLDKVRRK-KEEKAADRLEQELLRD-TVKFG--EVVLQPPELTARPQRSVSKD 219
K Q+ ++ + K +E++ R ++E++++ K G E +Q E R + + +
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576
Query: 220 QPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQAYRALKQRQQQLHGERPHL 279
+ R Q ++ + + ++ +++E+ E+ + + ++++++ + +
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636
Query: 280 TSRKK 284
+++
Sbjct: 637 RRQEE 641
Score = 37.7 bits (86), Expect = 0.012
Identities = 50/258 (19%), Positives = 116/258 (44%), Gaps = 23/258 (8%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEK----KKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
R+Q + + +Q W R +EK +K+ + K Q+++E+ +R E +R ++E I
Sbjct: 426 REQEEKIREQEKKMW---RQEEKIHEQEKIREEEKRQEQEEM-WRQEEKIREQEE----I 477
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
+K K Q RK EK + EE + + + E +++++ + + +
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR--EQ 535
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGEV 201
+ IR+ E ++ E+K ++ + + +K+RR++E+ + ++ ++ E
Sbjct: 536 EEKIREQEEMM---QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEE 592
Query: 202 VLQPPELTARPQRSVSKDQPGRRSQMLRMLLSPGGVSQPLTASLARQRIVEEERERAVQA 261
+ E R Q + ++Q + + + Q + RQ E+ E+ V+
Sbjct: 593 KIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE--EKMWEQEVR- 649
Query: 262 YRALKQRQQQLHGERPHL 279
L+Q+++++ + HL
Sbjct: 650 ---LRQQEEKMQEHQEHL 664
Score = 37.0 bits (84), Expect = 0.020
Identities = 33/152 (21%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Query: 43 LRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKKRKKAAQVTFR--KTLEK 100
+R +E+K + K + ++E+ + E MR ++EM K R+ + + K E
Sbjct: 323 IREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIREL 382
Query: 101 EAKGEEPD-IAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSKNQAIRQPEVQAAPKEKSE 159
E K E + I + K+++ E R +QEA+ + + IR+ E + +EK
Sbjct: 383 EEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK---MWRQEEKIREQEEKIREQEKKM 439
Query: 160 QKKAKKAFQKRRLDKVRRKKEEKAADRLEQEL 191
++ +K ++ ++ + +++E++ R E+++
Sbjct: 440 WRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471
Score = 34.3 bits (77), Expect = 0.13
Identities = 33/171 (19%), Positives = 79/171 (46%), Gaps = 13/171 (7%)
Query: 26 RQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPISNKK 85
R+Q + + +Q W KE+K + +++E RL E+M ++E + K
Sbjct: 331 REQEEKMRRQEEMMW----EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKM 386
Query: 86 RKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESD-GAYIHRMQQEAQHVLFLSKNQA 144
++ K E+E K +E + + K+++ E+ +++++ + + K
Sbjct: 387 HEQ------EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 440
Query: 145 IRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKE--EKAADRLEQELLR 193
++ ++ K + E+K+ ++ R+ +K+R ++E + EQE +R
Sbjct: 441 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIR 491
Score = 32.7 bits (73), Expect = 0.38
Identities = 34/179 (18%), Positives = 84/179 (46%), Gaps = 8/179 (4%)
Query: 26 RQQVQP----LGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRSRQEMKNPI 81
+QQ+Q LGK+ + L+++ ++ NQ ++E +R E ++ +E
Sbjct: 260 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQ 319
Query: 82 SNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEAQHVLFLSK 141
K R++ ++ R+ EK + EE + K ++ + + + + + + K
Sbjct: 320 EEKIREQEEKI--REQEEKMRRQEE--MMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEK 375
Query: 142 NQAIRQPEVQAAPKEKSEQKKAKKAFQKRRLDKVRRKKEEKAADRLEQELLRDTVKFGE 200
+ IR+ E + +EK +++ K+ +++ ++ +R+++E R E+++ K E
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.353
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,035,689
Number of Sequences: 37866
Number of extensions: 602837
Number of successful extensions: 5809
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 506
Number of HSP's that attempted gapping in prelim test: 3830
Number of HSP's gapped (non-prelim): 1645
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.