Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 40317626
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40317626 thrombospondin 1 precursor [Homo sapiens]
(1170 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 2543 0.0
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 1631 0.0
gi|40217843 cartilage oligomeric matrix protein precursor [Homo ... 754 0.0
gi|6005902 thrombospondin 3 precursor [Homo sapiens] 740 0.0
gi|31543806 thrombospondin 4 precursor [Homo sapiens] 723 0.0
gi|118572606 hemicentin 1 [Homo sapiens] 191 3e-48
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [... 158 3e-38
gi|4505737 complement factor properdin precursor [Homo sapiens] 156 1e-37
gi|223671861 complement factor properdin precursor [Homo sapiens] 156 1e-37
gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens] 147 8e-35
gi|134031945 SCO-spondin [Homo sapiens] 144 6e-34
gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens] 142 1e-33
gi|91982767 semaphorin 5B isoform 1 [Homo sapiens] 135 2e-31
gi|147904700 semaphorin 5A [Homo sapiens] 133 9e-31
gi|32261318 unc-5 homolog B [Homo sapiens] 105 3e-22
gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens] 103 1e-21
gi|16933525 unc5C [Homo sapiens] 101 4e-21
gi|209977117 unc-5 homolog D [Homo sapiens] 100 1e-20
gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens] 97 1e-19
gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens] 94 8e-19
gi|157427675 ADAM metallopeptidase with thrombospondin type 1 mo... 88 4e-17
gi|51558724 ADAM metallopeptidase with thrombospondin type 1 mot... 86 3e-16
gi|56121815 ADAM metallopeptidase with thrombospondin type 1 mot... 84 8e-16
gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 84 8e-16
gi|134244285 Notch homolog 3 [Homo sapiens] 84 1e-15
gi|153792351 ADAM metallopeptidase with thrombospondin type 1 mo... 83 1e-15
gi|33624896 ADAM metallopeptidase with thrombospondin type 1 mot... 82 3e-15
gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo s... 81 5e-15
gi|223718260 ADAMTS-like 2 precursor [Homo sapiens] 80 9e-15
gi|41281450 ADAMTS-like 2 precursor [Homo sapiens] 80 9e-15
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 2543 bits (6590), Expect = 0.0
Identities = 1170/1170 (100%), Positives = 1170/1170 (100%)
Query: 1 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR 60
MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR
Sbjct: 1 MGLAWGLGVLFLMHVCGTNRIPESGGDNSVFDIFELTGAARKGSGRRLVKGPDPSSPAFR 60
Query: 61 IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV 120
IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV
Sbjct: 61 IEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALERKDHSGQVFSVV 120
Query: 121 SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD 180
SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD
Sbjct: 121 SNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLYIDCEKMENAELD 180
Query: 181 VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL 240
VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL
Sbjct: 181 VPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLL 240
Query: 241 TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK 300
TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK
Sbjct: 241 TLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRK 300
Query: 301 VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN 360
VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN
Sbjct: 301 VTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSN 360
Query: 361 ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT 420
ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT
Sbjct: 361 ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT 420
Query: 421 RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE 480
RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE
Sbjct: 421 RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARE 480
Query: 481 TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI 540
TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI
Sbjct: 481 TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQI 540
Query: 541 CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF 600
CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF
Sbjct: 541 CNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF 600
Query: 601 NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN 660
NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN
Sbjct: 601 NHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN 660
Query: 661 AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN 720
AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN
Sbjct: 661 AKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPN 720
Query: 721 LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN 780
LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN
Sbjct: 721 LPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYN 780
Query: 781 HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH 840
HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH
Sbjct: 781 HNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEH 840
Query: 841 NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN 900
NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN
Sbjct: 841 NPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDN 900
Query: 901 DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF 960
DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF
Sbjct: 901 DGIPDDKDNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRF 960
Query: 961 QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD 1020
QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD
Sbjct: 961 QMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDD 1020
Query: 1021 DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL 1080
DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL
Sbjct: 1021 DYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNAL 1080
Query: 1081 WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD 1140
WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD
Sbjct: 1081 WHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYD 1140
Query: 1141 KTYAGGRLGLFVFSQEMVFFSDLKYECRDP 1170
KTYAGGRLGLFVFSQEMVFFSDLKYECRDP
Sbjct: 1141 KTYAGGRLGLFVFSQEMVFFSDLKYECRDP 1170
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 1631 bits (4223), Expect = 0.0
Identities = 720/1151 (62%), Positives = 887/1151 (77%), Gaps = 12/1151 (1%)
Query: 28 NSVFDIFELTGAARKGSGRRLVKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKG 87
++ FD+F ++ RK G + +GPDP PA+R + IPPV D + +R ++G
Sbjct: 24 DTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEG 83
Query: 88 FLLLASLRQMKKTRGTLLALERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEAL 147
F L A L+Q K+RGTLLALE S + F +VSNG A TLDL+ + G +HVVS+E+
Sbjct: 84 FFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWIDGTRHVVSLEDVG 143
Query: 148 LATGQWKSITLFVQEDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDN 207
LA QWK++T+ V + L++ C+ +++ LD P + A +R+ +AKG ++
Sbjct: 144 LADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPF---YEHLQAEKSRMYVAKGSARES 200
Query: 208 -FQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTL--DNNVVNGSSPAIRTNYIGHKTK 264
F+G+LQNV VF + EDIL KGC + +N P + T Y+G ++
Sbjct: 201 HFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGPSSE 260
Query: 265 DLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPP------LC 318
+C SC+EL +MV EL GL +V L +++++V+ +N+ L + PP C
Sbjct: 261 RRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSNDNQFLWELIGGPPKTRNMSAC 320
Query: 319 YHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSA 378
+ +G + NE W VDSCT C C+ TIC +++CP C++ + +GECCP C S
Sbjct: 321 WQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHSVDG 380
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGW 438
++GWSPW+EWT CS +CG+G QQRGRSCD +N C G S+QTR C + +CD R +QDGGW
Sbjct: 381 EEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGW 440
Query: 439 SHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPW 498
SHWSPWSSCSVTCG G ITRIRLCNSP PQM GK C+G RETKAC+ CPI+G W PW
Sbjct: 441 SHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPW 500
Query: 499 SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFA 558
SPW C+VTC GG+++R+R+CN+P PQ+GGK CVGDV E Q+CNK+ CP+DGCLSNPCF
Sbjct: 501 SPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFP 560
Query: 559 GVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCL 618
G +C+S+PDGSW CG+CP G+ GNG C D+DEC VPD CF+ + RC NT PG++CL
Sbjct: 561 GAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCL 620
Query: 619 PCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCEC 678
PCPPR+ G+QP G G+E A KQVC+P NPC D TH+C+K+A+C YLGH+SDPMY+CEC
Sbjct: 621 PCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCEC 680
Query: 679 KPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDAC 738
+ GYAG+G+ICGED+DLDGWPN NLVC NATYHC KDNCP+LPNSGQED+DKDGIGDAC
Sbjct: 681 QTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDAC 740
Query: 739 DDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACA 798
DDDDDND + D++DNC +NP Q DYD+D+VGDRCDNCPY HNP Q DTDNNGEGDAC+
Sbjct: 741 DDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACS 800
Query: 799 ADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDN 858
DIDGD + NERDNC YVYN DQRDTD DGVGD CDNCPL HNPDQ D D+D +GD CDN
Sbjct: 801 VDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDN 860
Query: 859 NQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQ 918
N+DID+DGHQNN DNCPY+ NANQADHD+DG+GDACD DDDNDG+PDD+DNCRLV NPDQ
Sbjct: 861 NEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQ 920
Query: 919 KDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWV 978
+D DGDGRGD CKDDFD+D++PDIDD+CPEN ISETDFR FQM+PLDPKGT+Q DPNWV
Sbjct: 921 EDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWV 980
Query: 979 VRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVV 1038
+RHQGKELVQT N DPG+AVG+DEF +VDFSGTF++NT+RDDDYAGFVFGYQSSSRFYVV
Sbjct: 981 IRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVV 1040
Query: 1039 MWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPR 1098
MWKQVTQ+YW+ PTRA GYSG+S+KVVNSTTG GEHLRNALWHTGNTPGQVRTLWHDPR
Sbjct: 1041 MWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPR 1100
Query: 1099 HIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMV 1158
+IGWKD+TAYRW L+HRPKTG+IRV+++EGK++MADSGPIYD+TYAGGRLGLFVFSQEMV
Sbjct: 1101 NIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMV 1160
Query: 1159 FFSDLKYECRD 1169
+FSDLKYECRD
Sbjct: 1161 YFSDLKYECRD 1171
>gi|40217843 cartilage oligomeric matrix protein precursor [Homo
sapiens]
Length = 757
Score = 754 bits (1947), Expect = 0.0
Identities = 356/666 (53%), Positives = 435/666 (65%), Gaps = 52/666 (7%)
Query: 547 PIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEH 606
P+ C CF GV C G+ +CG CP G++GNG CTDV+EC P CF
Sbjct: 87 PLLHCAPGFCFPGVACIQTESGA-RCGPCPAGFTGNGSHCTDVNECNAHP--CFPRV--- 140
Query: 607 RCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKC--- 663
RC NT PG+ C CPP ++G G G+ A ANKQVC N C G H+C N+ C
Sbjct: 141 RCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECETGQHNCVPNSVCINT 200
Query: 664 -----------NYLGHYSDPMYR-----------------------------CECKPGYA 683
++G + R C C G+A
Sbjct: 201 RGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVLERDGSRSCVCAVGWA 260
Query: 684 GNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDD 743
GNGI+CG DTDLDG+P+E L C C+KDNC +PNSGQED D+DGIGDACD D D
Sbjct: 261 GNGILCGRDTDLDGFPDEKLRCPER---QCRKDNCVTVPNSGQEDVDRDGIGDACDPDAD 317
Query: 744 NDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDG 803
D +P+++DNCP NP Q + D D GD CDNC N DQ DTD +G GDAC DIDG
Sbjct: 318 GDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQDGRGDACDDDIDG 377
Query: 804 DGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDID 863
D I N+ DNC V N DQ+D+D DG+GD CDNCP + NPDQ D D D +GD CD++QD D
Sbjct: 378 DRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDFVGDACDSDQDQD 437
Query: 864 EDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPDDKDNCRLVPNPDQKDSDG 923
DGHQ++ DNCP VPN+ Q D D DG+GDACD DDDNDG+PD +DNCRLVPNP Q+D+D
Sbjct: 438 GDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPDSRDNCRLVPNPGQEDADR 497
Query: 924 DGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQG 983
DG GD C+DDFD D V D D+CPEN +++ TDFR FQ + LDP+G +Q DPNWVV +QG
Sbjct: 498 DGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDPEGDAQIDPNWVVLNQG 557
Query: 984 KELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQV 1043
+E+VQT+N DPGLAVGY FN VDF GTF +NT DDDYAGF+FGYQ SS FYVVMWKQ+
Sbjct: 558 REIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIFGYQDSSSFYVVMWKQM 617
Query: 1044 TQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWK 1103
Q+YW NP RA G+ +K V S+TGPGE LRNALWHTG+T QVR LW DPR++GWK
Sbjct: 618 EQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTESQVRLLWKDPRNVGWK 677
Query: 1104 DFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDL 1163
D +YRW L HRP+ G+IRV YEG +++ADS + D T GGRLG+F FSQE + +++L
Sbjct: 678 DKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGRLGVFCFSQENIIWANL 737
Query: 1164 KYECRD 1169
+Y C D
Sbjct: 738 RYRCND 743
>gi|6005902 thrombospondin 3 precursor [Homo sapiens]
Length = 956
Score = 740 bits (1910), Expect = 0.0
Identities = 357/682 (52%), Positives = 442/682 (64%), Gaps = 53/682 (7%)
Query: 535 VTENQICNKQDCPIDGCLSNPCFAGVKCTS-YPDGSWKCGACPPGYSGNGIQCTDVDECK 593
+ E Q+C + C NPCF GV C Y ++CG CPPG GNG C+D++EC
Sbjct: 263 IMECQVCGFHE-QRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECA 321
Query: 594 EVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDG 653
D CF + C NT PG++C CP + G+Q G G+++A A+KQVC + C DG
Sbjct: 322 HA-DPCFPGSS---CINTMPGFHCEACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDG 377
Query: 654 THD-CNKNAKCN--------------YLGHYSD--------------PMY---------- 674
+ C+ N+ C +LG+ S P +
Sbjct: 378 NNGGCDPNSICTNTVGSFKCGPCRLGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERN 437
Query: 675 ---RCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDK 731
C+C G+AGNG +CG DTD+DG+P++ L C+ N HCK+DNC PNSGQED D
Sbjct: 438 GAVSCQCNVGWAGNGNVCGTDTDIDGYPDQALPCMDN-NKHCKQDNCLLTPNSGQEDADN 496
Query: 732 DGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNN 791
DG+GD CDDD D D I + DNC N Q + D D GD CDNCP N DQ DTD N
Sbjct: 497 DGVGDQCDDDADGDGIKNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGN 556
Query: 792 GEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDR 851
GEGDAC D+DGDGI N DNC V N Q D D DGVGD CD+CP NP Q D+DSD
Sbjct: 557 GEGDACDNDVDGDGIPNGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDL 616
Query: 852 IGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPD----DK 907
+GD CD N+D D DGHQ+ DNCP +PN++Q D D DG GD CD DDDNDGIPD
Sbjct: 617 VGDVCDTNEDSDGDGHQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGP 676
Query: 908 DNCRLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDP 967
DNCRLVPNP+QKDSDG+G GD C+DDFD+D+V D D+CPE+ +++ TDFR +Q + LDP
Sbjct: 677 DNCRLVPNPNQKDSDGNGVGDVCEDDFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDP 736
Query: 968 KGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVF 1027
+G +Q DPNWVV +QG E+VQT+N DPGLAVGY FN VDF GTF +NT DDDYAGF+F
Sbjct: 737 EGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLF 796
Query: 1028 GYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTP 1087
YQ S RFYVVMWKQ Q+YW P RA GL +K V S +GPGEHLRNALWHTG+TP
Sbjct: 797 SYQDSGRFYVVMWKQTEQTYWQATPFRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTP 856
Query: 1088 GQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGR 1147
QVR LW DPR++GW+D T+YRW+L HRP+ G+IRV +YEG +++ADSG I D + GGR
Sbjct: 857 DQVRLLWTDPRNVGWRDKTSYRWQLLHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGR 916
Query: 1148 LGLFVFSQEMVFFSDLKYECRD 1169
LG+F FSQE + +S+L+Y C D
Sbjct: 917 LGVFCFSQENIIWSNLQYRCND 938
Score = 100 bits (248), Expect = 1e-20
Identities = 182/780 (23%), Positives = 267/780 (34%), Gaps = 178/780 (22%)
Query: 90 LLASLRQMKKTRGTLLAL-ERKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALL 148
LL++ R K G L L R+D++ + + V L GK H V++++A L
Sbjct: 58 LLSTFRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGL 117
Query: 149 ATGQWKSITLFVQ-----EDRAQLYIDCEKMENAELDVPIQSVFTRDLASIARLRIAKG- 202
A G+ ++ L ++ LY+DC K+ + +P + A + L I G
Sbjct: 118 ADGRTHTVLLRLRGPSRPSPALHLYVDC-KLGDQHAGLPALAPIPP--AEVDGLEIRTGQ 174
Query: 203 GVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHK 262
QG +++++ + G + + C D ++ + + A+ + +G +
Sbjct: 175 KAYLRMQGFVESMKIILGGSMARVGALSECPFQG------DESIHSAVTNALH-SILGEQ 227
Query: 263 TKDLQAICGISCDELSSMVLELRGLRTIVTTLQDSIRKVTEENKELANELRRPPLC-YH- 320
TK ++V +L I+ L+D IR +E + N + +C +H
Sbjct: 228 TK--------------ALVTQLTLFNQILVELRDDIRDQVKEMSLIRNTIMECQVCGFHE 273
Query: 321 -----------NGVQYRNNEEWTVDSCTEC--HCQNSVTICKKVS-C----PIMPCSNA- 361
GV E+ C C Q + T C ++ C P P S+
Sbjct: 274 QRSHCSPNPCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCI 333
Query: 362 -TVPDGEC--CPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSV 418
T+P C CPR + ++ S N I + D N C+ +S+
Sbjct: 334 NTMPGFHCEACPRGYKGTQVS---GVGIDYARASKQVCNDIDECN---DGNNGGCDPNSI 387
Query: 419 QTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEA 478
T T +C G + S C R C+SP+ PC A
Sbjct: 388 CTNTVGSFKC--------GPCRLGFLGNQSQGC-----LPARTCHSPA----HSPCHIHA 430
Query: 479 R---ETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDV 535
E +C N GW G G +C T G D
Sbjct: 431 HCLFERNGAV--SCQCNVGW------------AGNG-----NVCGTDTDIDGYPDQALPC 471
Query: 536 TENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQC---TDVDEC 592
+ N + C D CL P G G G QC D D
Sbjct: 472 MD----NNKHCKQDNCLLTP---------------NSGQEDADNDGVGDQCDDDADGDGI 512
Query: 593 KEVPDAC--FNHNGEHRCENTDPGYNCLPCP--PRFTGSQPFGQGVEHATAN-------- 640
K V D C F + + + G C CP P G G A N
Sbjct: 513 KNVEDNCRLFPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIP 572
Query: 641 ---KQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDG 697
K NP + C+ S+P + + G+ ED+D DG
Sbjct: 573 NGLDNCPKVPNPLQTDRDEDGVGDACDSCPEMSNPT-QTDADSDLVGDVCDTNEDSDGDG 631
Query: 698 WPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPD----DRDN 753
+ KDNCP LPNS Q D D DG+GD CD DDDND IPD DN
Sbjct: 632 -------------HQDTKDNCPQLPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDN 678
Query: 754 CPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNERDNC 813
C NP Q D +D NG GD C D D D +++ D C
Sbjct: 679 CRLVPNPNQKD-----------------------SDGNGVGDVCEDDFDNDAVVDPLDVC 715
>gi|31543806 thrombospondin 4 precursor [Homo sapiens]
Length = 961
Score = 723 bits (1866), Expect = 0.0
Identities = 359/664 (54%), Positives = 430/664 (64%), Gaps = 56/664 (8%)
Query: 551 CLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCEN 610
C SNPCF GV+CT DG ++CG CP GY+GNGI C DVDECK P C+ G H C N
Sbjct: 290 CDSNPCFRGVQCTDSRDG-FQCGPCPEGYTGNGITCIDVDECKYHP--CYP--GVH-CIN 343
Query: 611 TDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKC-NYLGHY 669
PG+ C CP FTG G G+ A +NKQVC + C +G C N+ C N LG Y
Sbjct: 344 LSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGSY 401
Query: 670 S----DPMYR------------------------------------CECKPGYAGNGIIC 689
P Y C C G+AG+G IC
Sbjct: 402 RCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
Query: 690 GEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGIGDACDDDDDNDKIPD 749
G+D D+D +P+E L C A +CKKDNC +PNSGQED D+DGIGDACD+D D D I +
Sbjct: 462 GKDVDIDSYPDEELPCSAR---NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILN 518
Query: 750 DRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEGDACAADIDGDGILNE 809
++DNC +N Q + D+D GD CDNC N DQ DTD +G GDAC D+DGDGI N
Sbjct: 519 EQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNI 578
Query: 810 RDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGDTCDNNQDIDEDGHQN 869
DNC N DQRD D DGVGD CD+CP NP+Q D D+D +GD+CD NQD D DGHQ+
Sbjct: 579 LDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQD 638
Query: 870 NLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPD----DKDNCRLVPNPDQKDSDGDG 925
+ DNCP V N+ Q D DKDG GD CD DDDNDGIPD DNCRLVPNP Q+DS+ DG
Sbjct: 639 STDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDG 698
Query: 926 RGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGTSQNDPNWVVRHQGKE 985
GD C+ DFD D V D D+CPEN +++ TDFR +Q + LDP+G +Q DPNWVV +QG E
Sbjct: 699 VGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGME 758
Query: 986 LVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQSSSRFYVVMWKQVTQ 1045
+VQT+N DPGLAVGY FN VDF GTF +NT+ DDDYAGF+FGYQ SS FYVVMWKQ Q
Sbjct: 759 IVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQ 818
Query: 1046 SYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQVRTLWHDPRHIGWKDF 1105
+YW P RA G+ +K V S TGPGEHLRN+LWHTG+T QVR LW D R++GWKD
Sbjct: 819 TYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDK 878
Query: 1106 TAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGLFVFSQEMVFFSDLKY 1165
+YRW L HRP+ G+IRV YEG +++ADSG D T GGRLG+F FSQE + +S+LKY
Sbjct: 879 VSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKY 938
Query: 1166 ECRD 1169
C D
Sbjct: 939 RCND 942
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 191 bits (485), Expect = 3e-48
Identities = 102/271 (37%), Positives = 131/271 (48%), Gaps = 24/271 (8%)
Query: 381 GWSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHIQECDKRFKQD 435
G+S WS W +CS +CG GIQ+R R C+ C+GS ++ R C + C D
Sbjct: 4531 GFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPV----D 4586
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGW 495
G WS WS W C+ +CG G TR R CN+PS Q G+PCEG A E C CP++G W
Sbjct: 4587 GSWSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAW 4646
Query: 496 GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNP 555
W PW CS +CG G Q R+RLCNNP P FGG C G T+ Q+CN+++CPI G +
Sbjct: 4647 SAWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIHGKWATW 4706
Query: 556 CFAGVKCTSYPDGSWK----CGACPPGYSGNGIQCTDVDECKEVPDACFNH------NGE 605
S G+ + C P Y G + +DV D C H +G
Sbjct: 4707 ASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPWSGW 4766
Query: 606 HRCENTDPG-----YNCLPCPPRFTGSQPFG 631
C T G Y PP G + G
Sbjct: 4767 GTCSRTCNGGQMRRYRTCDNPPPSNGGRACG 4797
Score = 182 bits (461), Expect = 2e-45
Identities = 78/199 (39%), Positives = 111/199 (55%), Gaps = 12/199 (6%)
Query: 357 PCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN-----N 411
PC + + C + P D + WS WS W C+ SCG G Q R R+C++ +
Sbjct: 4567 PCQGSDLEMRNCQNKPCPVDGS---WSEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGR 4623
Query: 412 RCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNG 471
CEG++V+ C+I+ C G WS W PW +CS +CG G TR RLCN+P P G
Sbjct: 4624 PCEGNAVEIIMCNIRPCPVH----GAWSAWQPWGTCSESCGKGTQTRARLCNNPPPAFGG 4679
Query: 472 KPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDC 531
C+G + + C + CPI+G W W+ W CSV+CGGG ++R+R C++P PQ+GG+ C
Sbjct: 4680 SYCDGAETQMQVCNERNCPIHGKWATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKC 4739
Query: 532 VGDVTENQICNKQDCPIDG 550
G ++ CN CP G
Sbjct: 4740 EGSDVQSDFCNSDPCPTHG 4758
Score = 174 bits (440), Expect = 6e-43
Identities = 86/232 (37%), Positives = 118/232 (50%), Gaps = 18/232 (7%)
Query: 330 EWTV-DSCTECHCQNSVTICKKVSCPIM-----PCSNATVPDGECCPRCWPSDSADDGWS 383
EW++ + CT + + T + + P + PC V C R P A WS
Sbjct: 4591 EWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGA---WS 4647
Query: 384 PWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHIQECDKRFKQDGGW 438
W W +CS SCG G Q R R C++ + C+G+ Q + C+ + C G W
Sbjct: 4648 AWQPWGTCSESCGKGTQTRARLCNNPPPAFGGSYCDGAETQMQVCNERNCPIH----GKW 4703
Query: 439 SHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPW 498
+ W+ WS+CSV+CG G R R C+ P PQ G+ CEG ++ C D CP +G W PW
Sbjct: 4704 ATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTHGNWSPW 4763
Query: 499 SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
S W CS TC GG +R R C+NP P GG+ C G ++ Q CN CP+DG
Sbjct: 4764 SGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDG 4815
Score = 172 bits (435), Expect = 2e-42
Identities = 72/171 (42%), Positives = 95/171 (55%), Gaps = 9/171 (5%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHIQECDKRFKQDG 436
W+ W+ W++CS SCG G +QR R C +CEGS VQ+ C+ C G
Sbjct: 4703 WATWASWSACSVSCGGGARQRTRGCSDPVPQYGGRKCEGSDVQSDFCNSDPCPTH----G 4758
Query: 437 GWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWG 496
WS WS W +CS TC G + R R C++P P G+ C G + + C D CP++G WG
Sbjct: 4759 NWSPWSGWGTCSRTCNGGQMRRYRTCDNPPPSNGGRACGGPDSQIQRCNTDMCPVDGSWG 4818
Query: 497 PWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
W W CS +CGGG + R RLC++P P GG+ C GD T+ CN Q CP
Sbjct: 4819 SWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQACP 4869
Score = 141 bits (355), Expect = 4e-33
Identities = 64/151 (42%), Positives = 85/151 (56%), Gaps = 4/151 (2%)
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGW 495
GG+S WS W +CSVTCG G+ R RLCN P P GKPC+G E + C+ CP++G W
Sbjct: 4530 GGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDGSW 4589
Query: 496 GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNP 555
WS W+ C+ +CG G Q R+R CNNP+ Q GG+ C G+ E +CN + CP+ G S
Sbjct: 4590 SEWSLWEECTRSCGRGNQTRTRTCNNPSVQHGGRPCEGNAVEIIMCNIRPCPVHGAWSAW 4649
Query: 556 CFAGVKCTSYPDGSWK----CGACPPGYSGN 582
G S G+ C PP + G+
Sbjct: 4650 QPWGTCSESCGKGTQTRARLCNNPPPAFGGS 4680
Score = 82.0 bits (201), Expect = 3e-15
Identities = 34/63 (53%), Positives = 41/63 (65%)
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
++GG+ WS W CSVTCG G+QKRSRLCN P P GGK C G E + C + CP+DG
Sbjct: 4528 VHGGFSQWSAWRACSVTCGKGIQKRSRLCNQPLPANGGKPCQGSDLEMRNCQNKPCPVDG 4587
Query: 551 CLS 553
S
Sbjct: 4588 SWS 4590
Score = 70.1 bits (170), Expect = 1e-11
Identities = 53/187 (28%), Positives = 74/187 (39%), Gaps = 53/187 (28%)
Query: 504 CSVTCGGGVQKRSRLCNNPTPQFGGKDC--VGDVTENQICNKQDCPIDGCLSNPCFAGVK 561
C V CG G ++ S G C + + E+ C+++ CF +
Sbjct: 5173 CVVRCGSGFRRTS----------DGLSCQDINECQESSPCHQR-----------CFNAI- 5210
Query: 562 CTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLP-C 620
GS+ CG C PGY G +C DV+EC++ + C + C+NT GY C+ C
Sbjct: 5211 ------GSFHCG-CEPGYQLKGRKCMDVNECRQ--NVC---RPDQHCKNTRGGYKCIDLC 5258
Query: 621 PPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKP 680
P T A C + C DGTH C N C + YRC C
Sbjct: 5259 PNGMT------------KAENGTCIDIDECKDGTHQCRYNQIC----ENTRGSYRCVCPR 5302
Query: 681 GYAGNGI 687
GY G+
Sbjct: 5303 GYRSQGV 5309
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/439 (23%), Positives = 145/439 (33%), Gaps = 143/439 (32%)
Query: 391 CSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHI-QECDKRF-------KQDGGWSHWS 442
CS G I GR+C ++ G TCH Q+CD + G+ S
Sbjct: 5130 CSCPKGLTIAADGRTCQDIDECALGR----HTCHAGQDCDNTIGSYRCVVRCGSGFRRTS 5185
Query: 443 PWSSCSVT--CGDGVITRIRLCNS---------PSPQMNGKPCEGEARETKACKKDACPI 491
SC C + R N+ P Q+ G+ C + C+++ C
Sbjct: 5186 DGLSCQDINECQESSPCHQRCFNAIGSFHCGCEPGYQLKGRKC----MDVNECRQNVC-- 5239
Query: 492 NGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGC 551
P C T GG K LC N + EN C D DG
Sbjct: 5240 -------RPDQHCKNTRGG--YKCIDLCPNGMTK----------AENGTCIDIDECKDG- 5279
Query: 552 LSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGI--QCTDVDECKEVPDACFNHNGEHRCE 609
++ C C + GS++C CP GY G+ C D++EC++VP C H+C
Sbjct: 5280 -THQCRYNQICEN-TRGSYRC-VCPRGYRSQGVGRPCMDINECEQVPKPC-----AHQCS 5331
Query: 610 NTDPGYNCLPCPPRFTGSQPFGQ-------------GVEHATANKQVCKP---------- 646
NT + C+ CPP G G G ++++ N P
Sbjct: 5332 NTPGSFKCI-CPP---GQHLLGDGKSCAGLERLPNYGTQYSSYNLARFSPVRNNYQPQQH 5387
Query: 647 ----------------------------RNPCTDG---THD-------CNKNAKCNYLGH 668
R C +G +HD C C +
Sbjct: 5388 YRQYSHLYSSYSEYRNSRTSLSRTRRTIRKTCPEGSEASHDTCVDIDECENTDACQHECK 5447
Query: 669 YSDPMYRCECKPGY--AGNGIICGEDTDLDGWPNENLVCVAN-------ATYHCKKDNCP 719
+ Y+C C PGY NG C D+D +N+ C N +Y C CP
Sbjct: 5448 NTFGSYQCICPPGYQLTHNGKTC---QDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCP 5504
Query: 720 NLPNSGQEDYDKDGIGDAC 738
PN Y +D + C
Sbjct: 5505 --PN-----YQRDPVSGFC 5516
Score = 48.9 bits (115), Expect = 3e-05
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 5/55 (9%)
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSCD-----SLNNRCEGSSVQTRTCHIQEC 428
D W W W+ CS SCG G + R R CD C G + Q C++Q C
Sbjct: 4814 DGSWGSWHSWSQCSASCGGGEKTRKRLCDHPVPVKGGRPCPGDTTQVTRCNVQAC 4868
Score = 45.4 bits (106), Expect = 3e-04
Identities = 47/178 (26%), Positives = 69/178 (38%), Gaps = 41/178 (23%)
Query: 556 CFAGVKCTSYPD---GSWKCGACPPGYS--GNGIQCTDVDECKEVPDACFNHNGEHRCEN 610
C AG C+ G++ C +CP G + +G C D+DEC C H G+ C+N
Sbjct: 5111 CAAGNPCSHSCHNAMGTYYC-SCPKGLTIAADGRTCQDIDECALGRHTC--HAGQD-CDN 5166
Query: 611 TDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYS 670
T Y C+ G G T++ C+ N +C +++ C+ +
Sbjct: 5167 TIGSYRCVV---------RCGSGFRR-TSDGLSCQDIN-------ECQESSPCHQRCFNA 5209
Query: 671 DPMYRCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKK--------DNCPN 720
+ C C+PGY G C + NE V HCK D CPN
Sbjct: 5210 IGSFHCGCEPGYQLKGRKCMD-------VNECRQNVCRPDQHCKNTRGGYKCIDLCPN 5260
>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor
[Homo sapiens]
Length = 1584
Score = 158 bits (399), Expect = 3e-38
Identities = 87/238 (36%), Positives = 113/238 (47%), Gaps = 21/238 (8%)
Query: 358 CSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN---NRCE 414
C+N+ V CP W WS W+ CS++CG G + R R+C N CE
Sbjct: 400 CNNSAV-----CP-------VHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCE 447
Query: 415 GSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPC 474
G QT+ C+I C R DG W+ WS WS+CS +C G R R CN PS G C
Sbjct: 448 GPEKQTKFCNIALCPGR-AVDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAEC 504
Query: 475 EGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGD 534
+G ET+ C CP++G W W+ W CSVTCG G Q+R R+C+ P FGG C G
Sbjct: 505 QGHWVETRDCFLQQCPVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPF--FGGAACQGP 562
Query: 535 VTENQICNKQDCP-IDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDE 591
E + C Q CP F V P G CP +G ++ ++DE
Sbjct: 563 QDEYRQCGTQRCPEPHEICDEDNFGAVIWKETPAGEVAAVRCPRNATGLILRRCELDE 620
Score = 151 bits (381), Expect = 4e-36
Identities = 85/232 (36%), Positives = 105/232 (45%), Gaps = 41/232 (17%)
Query: 376 DSADDGWSPWSEWTSCSTSCGNGIQQRGRSC--DSLNNRCEGSSVQTRTCHIQECDKRFK 433
D A + WSPWS CS++CG G Q R R C S + +C G + R C+
Sbjct: 354 DPAAEEWSPWSV---CSSTCGEGWQTRTRFCVSSSYSTQCSGPLREQRLCNNSAV---CP 407
Query: 434 QDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACP--- 490
G W WSPWS CS TCG G R R C PQ G PCEG ++TK C CP
Sbjct: 408 VHGAWDEWSPWSLCSSTCGRGFRDRTRTCR--PPQFGGNPCEGPEKQTKFCNIALCPGRA 465
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
++G W WS W CS +C G Q+R+R CN P+ +GG +C G E + C Q CP+DG
Sbjct: 466 VDGNWNEWSSWSACSASCSQGRQQRTRECNGPS--YGGAECQGHWVETRDCFLQQCPVDG 523
Query: 551 ------------------------CLSNPCFAGVKCTSYPDGSWKCGA--CP 576
S P F G C D +CG CP
Sbjct: 524 KWQAWASWGSCSVTCGAGSQRRERVCSGPFFGGAACQGPQDEYRQCGTQRCP 575
Score = 133 bits (335), Expect = 9e-31
Identities = 76/214 (35%), Positives = 95/214 (44%), Gaps = 46/214 (21%)
Query: 378 ADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL----NNRCEGSSVQTRTCHIQEC----- 428
A GW WS W C+ CG G+Q R R+C CEG + R C+ + C
Sbjct: 260 ATGGWKLWSLWGECTRDCGGGLQTRTRTCLPAPGVEGGGCEGVLEEGRQCNREACGPAGR 319
Query: 429 -----------DKRFKQDGG-----------------WSHWSPWSSCSVTCGDGVITRIR 460
D R +++ G WSPWS CS TCG+G TR R
Sbjct: 320 TSSRSQSLRSTDARRREELGDELQQFGFPAPQTGDPAAEEWSPWSVCSSTCGEGWQTRTR 379
Query: 461 LCNSPSPQMNGKPCEGEARETKACKKDA-CPINGGWGPWSPWDICSVTCGGGVQKRSRLC 519
C S S C G RE + C A CP++G W WSPW +CS TCG G + R+R C
Sbjct: 380 FCVSSS---YSTQCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTC 436
Query: 520 NNPTPQFGGKDCVGDVTENQICNKQDCP---IDG 550
PQFGG C G + + CN CP +DG
Sbjct: 437 R--PPQFGGNPCEGPEKQTKFCNIALCPGRAVDG 468
Score = 108 bits (269), Expect = 4e-23
Identities = 66/215 (30%), Positives = 92/215 (42%), Gaps = 23/215 (10%)
Query: 307 ELANELRRPPLCYHNGVQYRNN--EEWTVDSCTECHC----QNSVTICKKVSCPIMPCSN 360
+ + LR LC ++ V + +EW+ S C ++ C+ PC
Sbjct: 389 QCSGPLREQRLCNNSAVCPVHGAWDEWSPWSLCSSTCGRGFRDRTRTCRPPQFGGNPCEG 448
Query: 361 ATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN---NRCEGSS 417
C P + D W+ WS W++CS SC G QQR R C+ + C+G
Sbjct: 449 PEKQTKFCNIALCPGRAVDGNWNEWSSWSACSASCSQGRQQRTRECNGPSYGGAECQGHW 508
Query: 418 VQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGE 477
V+TR C +Q+C DG W W+ W SCSVTCG G R R+C+ P G C+G
Sbjct: 509 VETRDCFLQQC----PVDGKWQAWASWGSCSVTCGAGSQRRERVCSGPF--FGGAACQGP 562
Query: 478 ARETKACKKDACPINGGWGPWSPWDICSVTCGGGV 512
E + C CP P +IC G V
Sbjct: 563 QDEYRQCGTQRCP--------EPHEICDEDNFGAV 589
>gi|4505737 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 156 bits (395), Expect = 1e-37
Identities = 88/256 (34%), Positives = 112/256 (43%), Gaps = 36/256 (14%)
Query: 365 DGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCD----SLNNRCEGSSVQT 420
D +CCP GWS W W CS +C G + R R+C+ C G + ++
Sbjct: 129 DQQCCPEM-------GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQES 181
Query: 421 RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVI----TRIRLCNSPSPQMN--GKPC 474
C Q+ G W+ W PW+ CS +C G TR R C++P P GKPC
Sbjct: 182 EACDTQQV---CPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPC 238
Query: 475 EGEARETKACKK-DACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVG 533
G A E + C CP+ GGWGPW P C VTCG G R CN+P PQ GG C G
Sbjct: 239 PGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAG 298
Query: 534 DVTENQICNKQ-DCPIDGCLS-----NPC----FAGVKCTSYPDGSWKCGACPPGYSGNG 583
D T ICN CP+DG +PC + C P G G G +G
Sbjct: 299 DATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIP-GQQSRGRTCRGRKFDG 357
Query: 584 IQCT----DVDECKEV 595
+C D+ C +
Sbjct: 358 HRCAGQQQDIRHCYSI 373
Score = 143 bits (361), Expect = 8e-34
Identities = 74/183 (40%), Positives = 93/183 (50%), Gaps = 18/183 (9%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSV------QTRTCHIQECDKRFKQD 435
WS WS W CS +C G Q R R C N +C G Q + C Q+C +
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC---CPEM 136
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKAC-KKDACPINGG 494
GGWS W PW CSVTC G TR R CN P+P+ G C G+A+E++AC + CP +G
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGH-CPGQAQESEACDTQQVCPTHGA 195
Query: 495 WGPWSPWDICSVTCGGG----VQKRSRLCNNPTP--QFGGKDCVGDVTENQIC-NKQDCP 547
W W PW CS +C GG + RSR C+ P P + GK C G E + C CP
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP 255
Query: 548 IDG 550
+ G
Sbjct: 256 VAG 258
Score = 84.3 bits (207), Expect = 6e-16
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 39/224 (17%)
Query: 331 WTVDSCTECHC---QNSVTICKKVSCPIMPCSNATVPDGECCP-------RCW--PSDSA 378
WT S + CH + T +K S P + P G+ CP RC P
Sbjct: 202 WTPCSAS-CHGGPHEPKETRSRKCSAP----EPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQ-ECDKRF 432
GW PW + C +CG G R+C+ + C G + +T C+ C
Sbjct: 257 AGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPV-- 314
Query: 433 KQDGGWSHWSPWSSC------SVTCGD--GVITRIRLCNSPSPQMNGKPCEGEARETKAC 484
DG W W WS C S++C + G +R R C + +G C G+ ++ + C
Sbjct: 315 --DGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGR--KFDGHRCAGQQQDIRHC 370
Query: 485 KK-DACPINGGWGPWSPWDICSVTCG-GGVQKRSRLCNNPTPQF 526
CP+ G W WS W +C CG + R RLC P++
Sbjct: 371 YSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKY 414
>gi|223671861 complement factor properdin precursor [Homo sapiens]
Length = 469
Score = 156 bits (395), Expect = 1e-37
Identities = 88/256 (34%), Positives = 112/256 (43%), Gaps = 36/256 (14%)
Query: 365 DGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCD----SLNNRCEGSSVQT 420
D +CCP GWS W W CS +C G + R R+C+ C G + ++
Sbjct: 129 DQQCCPEM-------GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGHCPGQAQES 181
Query: 421 RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVI----TRIRLCNSPSPQMN--GKPC 474
C Q+ G W+ W PW+ CS +C G TR R C++P P GKPC
Sbjct: 182 EACDTQQV---CPTHGAWATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPC 238
Query: 475 EGEARETKACKK-DACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVG 533
G A E + C CP+ GGWGPW P C VTCG G R CN+P PQ GG C G
Sbjct: 239 PGLAYEQRRCTGLPPCPVAGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAG 298
Query: 534 DVTENQICNKQ-DCPIDGCLS-----NPC----FAGVKCTSYPDGSWKCGACPPGYSGNG 583
D T ICN CP+DG +PC + C P G G G +G
Sbjct: 299 DATRTHICNTAVPCPVDGEWDSWGEWSPCIRRNMKSISCQEIP-GQQSRGRTCRGRKFDG 357
Query: 584 IQCT----DVDECKEV 595
+C D+ C +
Sbjct: 358 HRCAGQQQDIRHCYSI 373
Score = 143 bits (361), Expect = 8e-34
Identities = 74/183 (40%), Positives = 93/183 (50%), Gaps = 18/183 (9%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSV------QTRTCHIQECDKRFKQD 435
WS WS W CS +C G Q R R C N +C G Q + C Q+C +
Sbjct: 80 WSLWSTWAPCSVTCSEGSQLRYRRCVGWNGQCSGKVAPGTLEWQLQACEDQQC---CPEM 136
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKAC-KKDACPINGG 494
GGWS W PW CSVTC G TR R CN P+P+ G C G+A+E++AC + CP +G
Sbjct: 137 GGWSGWGPWEPCSVTCSKGTRTRRRACNHPAPKCGGH-CPGQAQESEACDTQQVCPTHGA 195
Query: 495 WGPWSPWDICSVTCGGG----VQKRSRLCNNPTP--QFGGKDCVGDVTENQIC-NKQDCP 547
W W PW CS +C GG + RSR C+ P P + GK C G E + C CP
Sbjct: 196 WATWGPWTPCSASCHGGPHEPKETRSRKCSAPEPSQKPPGKPCPGLAYEQRRCTGLPPCP 255
Query: 548 IDG 550
+ G
Sbjct: 256 VAG 258
Score = 84.3 bits (207), Expect = 6e-16
Identities = 63/224 (28%), Positives = 91/224 (40%), Gaps = 39/224 (17%)
Query: 331 WTVDSCTECHC---QNSVTICKKVSCPIMPCSNATVPDGECCP-------RCW--PSDSA 378
WT S + CH + T +K S P + P G+ CP RC P
Sbjct: 202 WTPCSAS-CHGGPHEPKETRSRKCSAP----EPSQKPPGKPCPGLAYEQRRCTGLPPCPV 256
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQ-ECDKRF 432
GW PW + C +CG G R+C+ + C G + +T C+ C
Sbjct: 257 AGGWGPWGPVSPCPVTCGLGQTMEQRTCNHPVPQHGGPFCAGDATRTHICNTAVPCPV-- 314
Query: 433 KQDGGWSHWSPWSSC------SVTCGD--GVITRIRLCNSPSPQMNGKPCEGEARETKAC 484
DG W W WS C S++C + G +R R C + +G C G+ ++ + C
Sbjct: 315 --DGEWDSWGEWSPCIRRNMKSISCQEIPGQQSRGRTCRGR--KFDGHRCAGQQQDIRHC 370
Query: 485 KK-DACPINGGWGPWSPWDICSVTCG-GGVQKRSRLCNNPTPQF 526
CP+ G W WS W +C CG + R RLC P++
Sbjct: 371 YSIQHCPLKGSWSEWSTWGLCMPPCGPNPTRARQRLCTPLLPKY 414
>gi|4502359 brain-specific angiogenesis inhibitor 3 [Homo sapiens]
Length = 1522
Score = 147 bits (370), Expect = 8e-35
Identities = 77/210 (36%), Positives = 101/210 (48%), Gaps = 9/210 (4%)
Query: 363 VPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS-LNNRCEGSSVQTR 421
VP + + + + + G WS+W++CS +CG G Q R R+C S C G ++R
Sbjct: 275 VPQEQADAAKFMAQTGESGVEEWSQWSTCSVTCGQGSQVRTRTCVSPYGTHCSGPLRESR 334
Query: 422 TCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARET 481
C+ G W WSPWS CS TCG G TR R C P Q G+PCEG
Sbjct: 335 VCNNTAL---CPVHGVWEEWSPWSLCSFTCGRGQRTRTRSCTPP--QYGGRPCEGPETHH 389
Query: 482 KACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQIC 541
K C CP++G W WS W CSVTC G Q+RSR C GG +C G E++ C
Sbjct: 390 KPCNIALCPVDGQWQEWSSWSQCSVTCSNGTQQRSRQCT--AAAHGGSECRGPWAESREC 447
Query: 542 NKQDCPIDGCLSNPCFAGVKCTSYPDGSWK 571
+C +G N C+ DG W+
Sbjct: 448 YNPECTANG-QWNQWGHWSGCSKSCDGGWE 476
Score = 126 bits (316), Expect = 1e-28
Identities = 62/169 (36%), Positives = 79/169 (46%), Gaps = 11/169 (6%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLN---NRCEGSSVQTRTCHIQECDKRFKQDGGW 438
W WS W+ CS +CG G + R RSC CEG + C+I C DG W
Sbjct: 348 WEEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIALCPV----DGQW 403
Query: 439 SHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPW 498
WS WS CSVTC +G R R C + + G C G E++ C C NG W W
Sbjct: 404 QEWSSWSQCSVTCSNGTQQRSRQCTAAAH--GGSECRGPWAESRECYNPECTANGQWNQW 461
Query: 499 SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
W CS +C GG ++R R C G+ C G E + C++Q CP
Sbjct: 462 GHWSGCSKSCDGGWERRIRTCQGAV--ITGQQCEGTGEEVRRCSEQRCP 508
Score = 92.8 bits (229), Expect = 2e-18
Identities = 59/195 (30%), Positives = 79/195 (40%), Gaps = 28/195 (14%)
Query: 317 LCYHNGVQYRNNEEWTVDSCTECHC----QNSVTICKKVSCPIMPCSNATVPDGECCPRC 372
LC +GV EEW+ S C + C PC C
Sbjct: 341 LCPVHGVW----EEWSPWSLCSFTCGRGQRTRTRSCTPPQYGGRPCEGPETHHKPCNIAL 396
Query: 373 WPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL---NNRCEGSSVQTRTCHIQECD 429
P D WS WS+ CS +C NG QQR R C + + C G ++R C+ EC
Sbjct: 397 CPVDGQWQEWSSWSQ---CSVTCSNGTQQRSRQCTAAAHGGSECRGPWAESRECYNPEC- 452
Query: 430 KRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
+G W+ W WS CS +C G RIR C + G+ CEG E + C + C
Sbjct: 453 ---TANGQWNQWGHWSGCSKSCDGGWERRIRTCQ--GAVITGQQCEGTGEEVRRCSEQRC 507
Query: 490 PINGGWGPWSPWDIC 504
P +P++IC
Sbjct: 508 P--------APYEIC 514
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 144 bits (362), Expect = 6e-34
Identities = 108/367 (29%), Positives = 146/367 (39%), Gaps = 76/367 (20%)
Query: 335 SCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTS 394
+C++C C+ +C+ CP+ PC GWS WS W C S
Sbjct: 2694 NCSQCVCEKGELLCQPGGCPL-PC----------------------GWSAWSSWAPCDRS 2730
Query: 395 CGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSV 449
CG+G++ R RS + CEG + + CH + F GW+ W+ WSSCS
Sbjct: 2731 CGSGVRARFRSPSNPPAAWGGAPCEGDRQELQGCHTVCGTEVF----GWTPWTSWSSCSQ 2786
Query: 450 TC-----GDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDIC 504
+C G G +R RLC SP C G+A + + C CP+ WG W+PW C
Sbjct: 2787 SCLAPGGGPGWRSRSRLCPSPGDSS----CPGDATQEEPCSPPVCPVPSIWGLWAPWSTC 2842
Query: 505 SVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTS 564
S C GG+Q R R C++ P G C G ++ + CN Q C C N F +
Sbjct: 2843 SAPCDGGIQTRGRSCSSLAP--GDTTCPGPHSQTRDCNTQPCTAQ-CPENMLFRSAE-QC 2898
Query: 565 YPDGSWKCGACPP--GYSGNGIQCTD--VDECKEVPDACFNHNGEHRCENTDPGYNCLP- 619
+ +G G CP G GI+CT C P F HN +CLP
Sbjct: 2899 HQEG----GPCPRLCLTQGPGIECTGFCAPGC-TCPPGLFLHNA-----------SCLPR 2942
Query: 620 --CPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKN---AKCNYLGHYSDPMY 674
CP + G Q + G A A C C G C C + +
Sbjct: 2943 SQCPCQLHG-QLYASG---AMARLDSCN-NCTCVSGKMACTSERCPVACGWSPWTLWSLC 2997
Query: 675 RCECKPG 681
C C G
Sbjct: 2998 SCSCNVG 3004
Score = 132 bits (332), Expect = 2e-30
Identities = 91/312 (29%), Positives = 124/312 (39%), Gaps = 53/312 (16%)
Query: 351 VSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQ--RGRSCDS 408
+ CP C A E P GW PWS W+ CS SC + + R R+
Sbjct: 3858 LECPSPDCPGAEGSTVE------PVTGLPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLC 3911
Query: 409 LNNRCEGSSVQTRTCHIQECDKRFKQDG--------GWSHWSPWSSCSVTCGDGVITRIR 460
L N G +Q R C++ C + G W+ W+PW CS +CG G R+R
Sbjct: 3912 LANCTMGDPLQERPCNLPSCTELPVCPGPGCGAGNCSWTSWAPWEPCSRSCGVGQQRRLR 3971
Query: 461 LCNSPSPQMNGKPCEGEA-RETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLC 519
P P + P A +E + C ACP+ GGW WSPW C +CGGG RSR C
Sbjct: 3972 AYRPPGPGGHWCPNILTAYQERRFCNLRACPVPGGWSRWSPWSWCDRSCGGGQSLRSRSC 4031
Query: 520 NNPTPQFGGKDCVGDVTENQICNKQDCPIDGC--------LSNPCFAGVKCTSYPDG--- 568
++P + GG C G+ + ++CN C GC +N C +C+ +G
Sbjct: 4032 SSPPSKNGGAPCAGERHQARLCNPMPCEA-GCPAGMEVVTCANRC--PRRCSDLQEGIVC 4088
Query: 569 -----SWKCGACPPGYSGNGIQCTDVDEC-------------KEVPDACFNHNGEHRCEN 610
K CP G C + C + DAC N + C+
Sbjct: 4089 QDDQVCQKGCRCPKGSLEQDGGCVPIGHCDCTDAQGHSWAPGSQHQDACNNCS----CQA 4144
Query: 611 TDPGYNCLPCPP 622
PCPP
Sbjct: 4145 GQLSCTAQPCPP 4156
Score = 122 bits (305), Expect = 3e-27
Identities = 77/229 (33%), Positives = 94/229 (41%), Gaps = 53/229 (23%)
Query: 438 WSHWSPWSSCSVTCGDGVITRIRLC-NSPS-----------PQMNGKPCEGEARETKACK 485
WS W+PWS CS +CG R R C SPS P C G E + C
Sbjct: 3186 WSPWTPWSQCSASCGPARCHRHRFCARSPSAVPSTVAPLPLPATPTPLCSGPEAEEEPCL 3245
Query: 486 KDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQD 545
C GGWGPW PW CS +CGGG++ R+R C+ P PQ G C G + ++C
Sbjct: 3246 LQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQGLGDYCEGPRAQGEVCQALP 3305
Query: 546 CPIDGCLS------NPCFAGVKCTSYPDG----SWKCGA---CPPG--YSGNGIQCTDVD 590
CP+ C + +PC G C D W+C CPPG S NG C
Sbjct: 3306 CPVTNCTAIEGAEYSPC--GPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAICVQPG 3363
Query: 591 ECKEV----------------PDACFNHNGEHRCENTDPGYNC--LPCP 621
C + PD C NH C + NC LPCP
Sbjct: 3364 HCSCLDLLTGQRHHPGARLARPDGC-NH-----CTCLEGRLNCTDLPCP 3406
Score = 110 bits (275), Expect = 8e-24
Identities = 103/389 (26%), Positives = 134/389 (34%), Gaps = 78/389 (20%)
Query: 354 PIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS----- 408
P P + P+ E P GW PW W+ CS SCG G++ R R+CD
Sbjct: 3227 PATPTPLCSGPEAEEEPCLLQGCDRAGGWGPWGPWSHCSRSCGGGLRSRTRACDQPPPQG 3286
Query: 409 LNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSS-CSVTCGDGVITRIRL---CNS 464
L + CEG Q C C + +SP C +C D V R C
Sbjct: 3287 LGDYCEGPRAQGEVCQALPCPVTNCTAIEGAEYSPCGPPCPRSCDDLVHCVWRCQPGCYC 3346
Query: 465 PSPQM---NGKPC------------EGEARETKA-------------------CKKDACP 490
P Q+ NG C G+ A C CP
Sbjct: 3347 PPGQVLSSNGAICVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCP 3406
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQD----- 545
+ GGW PWS W +CS C G + RSR C PTPQ GG C G+ E ++++
Sbjct: 3407 VPGGWCPWSEWTMCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSY 3466
Query: 546 --CPIDGCLSNPCFAGVKCTSYPDGSWK-CGACPPGYSGNGIQCTDVDECKEVPDACFNH 602
CP+DG P G W C C G S C+ + NH
Sbjct: 3467 ATCPVDGAWG------------PWGPWSPCDMC-LGQSHRSRACSRPPTPEGGRPCPGNH 3513
Query: 603 NGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAK 662
C+ C C G Q + + Q P + C G+ C
Sbjct: 3514 TQSRPCQENST--QCTDC----GGGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCG 3567
Query: 663 CNYLGHYSD------PMY-RCECKPGYAG 684
C LG S P + RC+ +PG G
Sbjct: 3568 CP-LGQLSQDGLCVPPAHCRCQYQPGAMG 3595
Score = 107 bits (266), Expect = 9e-23
Identities = 86/320 (26%), Positives = 118/320 (36%), Gaps = 66/320 (20%)
Query: 358 CSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL---NNRCE 414
C + C P P S W W+ W++CS C GIQ RGRSC SL + C
Sbjct: 2812 CPGDATQEEPCSPPVCPVPSI---WGLWAPWSTCSAPCDGGIQTRGRSCSSLAPGDTTCP 2868
Query: 415 GSSVQTRTCHIQECD------------KRFKQDGG-----WSHWSPWSSCS------VTC 451
G QTR C+ Q C ++ Q+GG P C+ TC
Sbjct: 2869 GPHSQTRDCNTQPCTAQCPENMLFRSAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTC 2928
Query: 452 GDGVITRIRLC--NSPSP-QMNGKPCEGEARET-------------KACKKDACPINGGW 495
G+ C S P Q++G+ A AC + CP+ GW
Sbjct: 2929 PPGLFLHNASCLPRSQCPCQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPVACGW 2988
Query: 496 GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG----- 550
PW+ W +CS +C G+++R R P FGG +C G E + C+ + CP G
Sbjct: 2989 SPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPCPGPGGEWGP 3048
Query: 551 --CLSNPCFAGVKCTSYPD----------GSWKCGACPPGYSGNGIQCTDVDECKEVPDA 598
S PC G + + G C PG Q D C + P +
Sbjct: 3049 WSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPVPGMCPRDKQWLD---CAQGPAS 3105
Query: 599 CFNHNGEHRCENT-DPGYNC 617
C + T PG +C
Sbjct: 3106 CAELSAPRGTNQTCHPGCHC 3125
Score = 103 bits (258), Expect = 7e-22
Identities = 75/267 (28%), Positives = 100/267 (37%), Gaps = 37/267 (13%)
Query: 347 ICKKVSCPIMPCSNATVPD-GECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRS 405
+C+ + CP+ C+ + C P C P D W C G + G
Sbjct: 3300 VCQALPCPVTNCTAIEGAEYSPCGPPC-PRSCDDLVHCVWRCQPGCYCPPGQVLSSNGAI 3358
Query: 406 C---------DSLNNRCEGSSVQTRT---CHIQEC--------DKRFKQDGGWSHWSPWS 445
C D L + + C+ C D GGW WS W+
Sbjct: 3359 CVQPGHCSCLDLLTGQRHHPGARLARPDGCNHCTCLEGRLNCTDLPCPVPGGWCPWSEWT 3418
Query: 446 SCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARET------KACKKDA-CPINGGWGPW 498
CS C +R R C P+PQ G PC GEA E +AC A CP++G WGPW
Sbjct: 3419 MCSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPW 3478
Query: 499 SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGC----LSN 554
PW C + G RSR C+ P GG+ C G+ T+++ C + C +
Sbjct: 3479 GPWSPCDMCL--GQSHRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLH 3536
Query: 555 PCFAGVKCTSYPDGSWKCGACPPGYSG 581
PC G C C PG G
Sbjct: 3537 PC--GQPCPRSCQDLSPGSVCQPGSVG 3561
Score = 97.1 bits (240), Expect = 9e-20
Identities = 62/182 (34%), Positives = 75/182 (41%), Gaps = 36/182 (19%)
Query: 356 MPCSNATVPDGECC---------PRCW--------PSDSADDGWSPWSEWTSCSTSCGNG 398
+PC T P+G C P C P + W PWS W CS +CG
Sbjct: 1654 LPCPEYTCPNGTCIGFQLVCDGQPDCGRPGQVGPSPEEQGCGAWGPWSPWGPCSRTCGPW 1713
Query: 399 IQQRGRSCDSLN----NRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDG 454
Q R R C L C G Q++ C C DG WS WSPWS CS C G
Sbjct: 1714 GQGRSRRCSPLGLLVLQNCPGPEHQSQACFTAAC----PVDGEWSTWSPWSVCSEPC-RG 1768
Query: 455 VITRIRLCNSPSPQMNGKPCEG------EARETKACKKDACP--INGGWGPWSPWDICSV 506
+TR R C+ SPQ G+ C R+TK C +D CP G + P C +
Sbjct: 1769 TMTRQRQCH--SPQNGGRTCAALPGGLHSTRQTKPCPQDGCPNATCSGELMFQPCAPCPL 1826
Query: 507 TC 508
TC
Sbjct: 1827 TC 1828
Score = 96.7 bits (239), Expect = 1e-19
Identities = 71/227 (31%), Positives = 90/227 (39%), Gaps = 49/227 (21%)
Query: 394 SCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGG----WSHWSPWSSCSV 449
SCG+G C S RC+ +C +DG + WS WSSCS
Sbjct: 2470 SCGSG------ECLSAERRCDLRP---------DCQDGSDEDGCVDCVLAPWSVWSSCSR 2514
Query: 450 TCGDGV-ITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTC 508
+CG G+ R L P P G C + +++C ACP+ G W W W CSV+C
Sbjct: 2515 SCGLGLTFQRQELLRPPLP---GGSCPRDRFRSQSCFVQACPVAGAWAMWEAWGPCSVSC 2571
Query: 509 GGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDC-------------PIDGC---L 552
GGG Q R R C +P P+ GG C G E C Q C D C L
Sbjct: 2572 GGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCELGRVYVSADLCQKGL 2631
Query: 553 SNPCFAGVKCTSYPDGSWKCGA-------CPPGYSGNGIQCTDVDEC 592
PC C P + C CPPG + +C + EC
Sbjct: 2632 VPPC--PPSCLD-PKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSEC 2675
Score = 92.8 bits (229), Expect = 2e-18
Identities = 57/167 (34%), Positives = 75/167 (44%), Gaps = 32/167 (19%)
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGW 495
G W WSPW CS TCG R R C SP + + C G +++AC ACP++G W
Sbjct: 1695 GAWGPWSPWGPCSRTCGPWGQGRSRRC-SPLGLLVLQNCPGPEHQSQACFTAACPVDGEW 1753
Query: 496 GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCV---GDVTENQICNKQDCPIDGCL 552
WSPW +CS C G R R C+ +PQ GG+ C G + + + CP DGC
Sbjct: 1754 STWSPWSVCSEPC-RGTMTRQRQCH--SPQNGGRTCAALPGGLHSTR--QTKPCPQDGCP 1808
Query: 553 SNPCFAGV-----------------KCTSYPDGSWKCGA----CPPG 578
+ C + + T PD W CG+ CP G
Sbjct: 1809 NATCSGELMFQPCAPCPLTCDDISGQVTCPPD--WPCGSPGCWCPEG 1853
Score = 92.4 bits (228), Expect = 2e-18
Identities = 79/285 (27%), Positives = 99/285 (34%), Gaps = 83/285 (29%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCST 393
D+C C CQ ++SC PC P C WS WS W+ CS
Sbjct: 4135 DACNNCSCQ-----AGQLSCTAQPCP----PPTHC------------AWSHWSAWSPCSH 4173
Query: 394 SCG-NGIQQRGRSCDSLN--NRCEGSSVQTRTCHIQEC---------------------- 428
SCG G Q R RS S + C Q++ C C
Sbjct: 4174 SCGPRGQQSRFRSSTSGSWAPECREEQSQSQPCPQPSCPPLCLQGTRSRTLGDSWLQGEC 4233
Query: 429 -------------DKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCE 475
D W+ WS WS C V+CG G R R C + +P PC
Sbjct: 4234 QRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGGGNQVRTRACRAAAPHHRSPPCL 4293
Query: 476 GEARETKACKKDACP---INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCV 532
G +T ++ CP WGPW P CS +CG G+ RS C P K
Sbjct: 4294 GPDTQT---RQQPCPGLLEACSWGPWGP---CSRSCGPGLASRSGSC----PCLMAK--- 4340
Query: 533 GDVTENQICNKQDCPID--GCLSNPCFAGVKCTSYPDGSWKCGAC 575
+ CN +D GC S PC +C SW +C
Sbjct: 4341 ----ADPTCNSTFLHLDTQGCYSGPC--PEECVWSSWSSWTRCSC 4379
Score = 85.1 bits (209), Expect = 4e-16
Identities = 71/256 (27%), Positives = 96/256 (37%), Gaps = 69/256 (26%)
Query: 334 DSCTE-CHCQNSVTICKKVSCPIMPCS---------NATVPDGECCPRCWPSDSADDGWS 383
+ C E CHC + PC AT+ G+ P D D G
Sbjct: 3728 EGCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATI--GDPGQPLGPGDELDSG-- 3783
Query: 384 PWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSP 443
+ TSCGN C + + +C + +C F+ DGG+ WSP
Sbjct: 3784 -----QTLRTSCGN--------CSCAHGKL--------SCSLDDC---FEADGGFGPWSP 3819
Query: 444 WSSCSVTCGD-GVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACP------------ 490
W CS +CG G TR R C P ++G+ C G R+ C CP
Sbjct: 3820 WGPCSRSCGGLGTRTRSRQCVLTMPTLSGQGCRG-PRQDLECPSPDCPGAEGSTVEPVTG 3878
Query: 491 INGGWGPWSPWDICSVTCGGGV----QKRSRLCNNPTPQFGGKDCVGDVTENQICNKQD- 545
+ GGWGPWS W CS +C + R+RLC +GD + + CN
Sbjct: 3879 LPGGWGPWSSWSPCSRSCTDPARPAWRSRTRLCL-------ANCTMGDPLQERPCNLPSC 3931
Query: 546 -----CPIDGCLSNPC 556
CP GC + C
Sbjct: 3932 TELPVCPGPGCGAGNC 3947
Score = 82.4 bits (202), Expect = 2e-15
Identities = 72/294 (24%), Positives = 105/294 (35%), Gaps = 68/294 (23%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCST 393
D C C C C + CP+ GW PWSEWT CS
Sbjct: 3386 DGCNHCTCLEGRLNCTDLPCPV-----------------------PGGWCPWSEWTMCSQ 3422
Query: 394 SCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQECDKRFKQ---DGGWSHWSPWS 445
C + R R+C + C G + + H +E + DG W W PWS
Sbjct: 3423 PCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPSYATCPVDGAWGPWGPWS 3482
Query: 446 SCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDA--CPINGGWGPWSPWDI 503
C + G R R C+ P G+PC G +++ C++++ C GG P
Sbjct: 3483 PCDMCLGQS--HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCGGGQSLHP--- 3537
Query: 504 CSVTCGGGVQKRSRLCNNPTP----QFGGKDC-------VGDVTENQIC-NKQDCPIDGC 551
CG Q R C + +P Q G C +G ++++ +C C C
Sbjct: 3538 ----CG---QPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHC---RC 3587
Query: 552 LSNPCFAGV-----KCTSYPDGSWKC---GACPPGYSGNGIQCTDVDECKEVPD 597
P G+ + SW+ G G N + +C+EVPD
Sbjct: 3588 QYQPGAMGIPENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPD 3641
Score = 79.3 bits (194), Expect = 2e-14
Identities = 71/291 (24%), Positives = 107/291 (36%), Gaps = 78/291 (26%)
Query: 318 CYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDS 377
C +G Y + +DSC C C + C CP+ C
Sbjct: 2947 CQLHGQLYASGAMARLDSCNNCTCVSGKMACTSERCPV------------AC-------- 2986
Query: 378 ADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHIQECDKRF 432
GWSPW+ W+ CS SC GI++R R+ + C+G +++ C ++ C
Sbjct: 2987 ---GWSPWTLWSLCSCSCNVGIRRRFRAGTAPPAAFGGAECQGPTMEAEFCSLRPC---- 3039
Query: 433 KQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNG---KPCEGEARETKACKKDAC 489
G W PWS CSV CG G R R + + + +PC G C +D
Sbjct: 3040 --PGPGGEWGPWSPCSVPCGGGYRNRTRGSSRSLMEFSTCGLQPCAGPV--PGMCPRDKQ 3095
Query: 490 PINGGWGPWSPWDI-----CSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQIC-NK 543
++ GP S ++ + TC G C+ P+ G + N +C
Sbjct: 3096 WLDCAQGPASCAELSAPRGTNQTCHPG-------CHCPS---------GMLLLNNVCVPT 3139
Query: 544 QDCP--------------IDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYS 580
QDCP + C + C +G+ SW C P +S
Sbjct: 3140 QDCPCAHEGHLYPPGSTVVRPCENCSCVSGLIANC---SSWPCAEGEPTWS 3187
Score = 77.4 bits (189), Expect = 7e-14
Identities = 78/289 (26%), Positives = 100/289 (34%), Gaps = 45/289 (15%)
Query: 354 PIMPCS--NATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCG--NGIQQRGRSCDSL 409
P PC GEC PR W D +D + S+ C C + RG C S
Sbjct: 1561 PAPPCGPFEFRCGSGECTPRGWRCDQEED-CADGSDERGCGGPCAPHHAPCARGPHCVSP 1619
Query: 410 NNRCEGSSVQTRTCHIQECDKRFKQDG----GWSHWSPWSSCSVTCGDGVITRIRLCNSP 465
C+G R C + G G + + TC +G +L
Sbjct: 1620 EQLCDG----VRQCPDGSDEGPDACGGLPALGGPNRTGLPCPEYTCPNGTCIGFQLVCDG 1675
Query: 466 SPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQ 525
P G + E + C G WGPWSPW CS TCG Q RSR C +P
Sbjct: 1676 QPDCGRPGQVGPSPEEQGC--------GAWGPWSPWGPCSRTCGPWGQGRSRRC-SPLGL 1726
Query: 526 FGGKDCVGDVTENQICNKQDCPIDG---------CLSNPCFAGV----KCTSYPDGSWKC 572
++C G ++Q C CP+DG S PC + +C S +G C
Sbjct: 1727 LVLQNCPGPEHQSQACFTAACPVDGEWSTWSPWSVCSEPCRGTMTRQRQCHSPQNGGRTC 1786
Query: 573 GACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCP 621
A P G C + D C N C C PCP
Sbjct: 1787 AALPGGLHST----RQTKPCPQ--DGCPNAT----CSGELMFQPCAPCP 1825
Score = 76.3 bits (186), Expect = 2e-13
Identities = 85/351 (24%), Positives = 121/351 (34%), Gaps = 103/351 (29%)
Query: 330 EWTVDSCTECHCQNSVTICKKVSCPI-----MPCSNATVPDG-----ECCPRCWPSDSAD 379
EWT+ C++ + + + +CP PC+ G E CP + + D
Sbjct: 3416 EWTM--CSQPCRGQTRSRSRACACPTPQHGGAPCTGEAGEAGAQHQREACPS-YATCPVD 3472
Query: 380 DGWSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHI--------- 425
W PW W+ C G R R+C C G+ Q+R C
Sbjct: 3473 GAWGPWGPWSPCDMCLGQS--HRSRACSRPPTPEGGRPCPGNHTQSRPCQENSTQCTDCG 3530
Query: 426 ---------QECDKRFKQDGGWSHWSPWS-SCSVTCGD--GVITRIRLCNSPS------- 466
Q C + + S P S C TCG G +++ LC P+
Sbjct: 3531 GGQSLHPCGQPCPRSCQDLSPGSVCQPGSVGCQPTCGCPLGQLSQDGLCVPPAHCRCQYQ 3590
Query: 467 PQMNGKPCEGEARETKA-----------------------------CKK-DACPINGGWG 496
P G P E ++R + C++ CP G W
Sbjct: 3591 PGAMGIP-ENQSRSAGSRFSSWESLEPGEVVTGPCDNCTCVAGILQCQEVPDCPDPGVWS 3649
Query: 497 PWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGC----L 552
W PW+ CSV+CGGG Q RSR C P C G +++ C+ Q C GC L
Sbjct: 3650 SWGPWEDCSVSCGGGEQLRSRRCARP-------PCPGPARQSRTCSTQVCREAGCPAGRL 3702
Query: 553 SNPCFAGVKCT-----------SYPDGSWKCGACPPGYSGNGIQCTDVDEC 592
C G C + +G + CP G + + C V EC
Sbjct: 3703 YRECQPGEGCPFSCAHVTQQVGCFSEGCEEGCHCPEGTFQHRLAC--VQEC 3751
Score = 75.1 bits (183), Expect = 4e-13
Identities = 57/209 (27%), Positives = 74/209 (35%), Gaps = 49/209 (23%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSC-----DSLNNRCEGSSVQTRTCHIQECDKRFKQDG 436
W+ W W CS SCG G Q R RSC + C G+S + C +Q C +
Sbjct: 2558 WAMWEAWGPCSVSCGGGHQSRQRSCVDPPPKNGGAPCPGASQERAPCGLQPCSGGTDCEL 2617
Query: 437 GWSHWSP-------WSSCSVTCGDGVITR------IRLCNSPSPQM-------------- 469
G + S C +C D R + C P +
Sbjct: 2618 GRVYVSADLCQKGLVPPCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPC 2677
Query: 470 ----------------NGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQ 513
N C E E C+ CP+ GW WS W C +CG GV+
Sbjct: 2678 LVGEELKWPGVSFLLGNCSQCVCEKGEL-LCQPGGCPLPCGWSAWSSWAPCDRSCGSGVR 2736
Query: 514 KRSRLCNNPTPQFGGKDCVGDVTENQICN 542
R R +NP +GG C GD E Q C+
Sbjct: 2737 ARFRSPSNPPAAWGGAPCEGDRQELQGCH 2765
Score = 65.9 bits (159), Expect = 2e-10
Identities = 73/292 (25%), Positives = 93/292 (31%), Gaps = 82/292 (28%)
Query: 364 PDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQT--- 420
PD CP DS WS W W+ C C G + R R ++L C G +
Sbjct: 4607 PDPGACP-----DSCQ--WSLWGPWSPCQVPCSGGFRLRWREAEAL---CGGGCREPWAQ 4656
Query: 421 RTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGD--------------------------G 454
+C+ C + QD ++ + C +C D G
Sbjct: 4657 ESCNGGPCPECEAQDTVFT-LDCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDG 4715
Query: 455 VITRIRLCNSPSPQMNGK----PCEGE---------ARETKACKKDACPINGGWGPWSPW 501
I C P N P + E+ C CP+ GPWS W
Sbjct: 4716 RCVPISSCRCGLPSANASWELAPAQAVQLDCQNCTCVNESLVCPHQECPV---LGPWSAW 4772
Query: 502 DICSVTCGGGVQKRSRLCNNPTPQFGGKDC-VGDVTENQICNKQDCP-------IDGCLS 553
CS CGGG +R R C G C D + Q CN Q CP + C +
Sbjct: 4773 SSCSAPCGGGTMERHRTCEGGP---GVAPCQAQDTEQRQECNLQPCPECPPGQVLSACAT 4829
Query: 554 N-PCFA-----GVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDAC 599
+ PC G C P C PG G Q C P AC
Sbjct: 4830 SCPCLCWHLQPGAICVQEP--------CQPGCGCPGGQLLHNGTCVP-PTAC 4872
Score = 65.1 bits (157), Expect = 4e-10
Identities = 59/221 (26%), Positives = 77/221 (34%), Gaps = 51/221 (23%)
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDG-- 436
D WS WS W+ CS C G R R C S N + H K QDG
Sbjct: 1750 DGEWSTWSPWSVCSEPC-RGTMTRQRQCHSPQNGGRTCAALPGGLHSTRQTKPCPQDGCP 1808
Query: 437 -----GWSHWSPWSSCSVTCGD--GVIT-------RIRLCNSPSPQMNGK---------- 472
G + P + C +TC D G +T C P Q+ G
Sbjct: 1809 NATCSGELMFQPCAPCPLTCDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCVWPRQC 1868
Query: 473 PC--EG-------------------EARETKACKKDACPINGGWGPWSPWDICSVTCGG- 510
PC +G + R + C ++ GW WSPW C CG
Sbjct: 1869 PCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDCAVDCGWSSWSPWAKCLGPCGSQ 1928
Query: 511 GVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGC 551
+Q R NNP P G+ C G + + C + C +GC
Sbjct: 1929 SIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC--EGC 1967
Score = 61.6 bits (148), Expect = 4e-09
Identities = 43/165 (26%), Positives = 60/165 (36%), Gaps = 14/165 (8%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPCSNAT-----VPDGEC-CPRCWPSDSADDGWSPWSE 387
D C C + CP+ C + + PD C P CW + G W
Sbjct: 1805 DGCPNATCSGELMFQPCAPCPLT-CDDISGQVTCPPDWPCGSPGCWCPEGQVLGSEGWCV 1863
Query: 388 WT-SCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ-ECDKRFKQDGGWSHWSPWS 445
W C G+ + C + R C + +C D GWS WSPW+
Sbjct: 1864 WPRQCPCLVDGARYWPGQRIKADCQLCICQDGRPRRCRLNPDC----AVDCGWSSWSPWA 1919
Query: 446 SCSVTCGDGVIT-RIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
C CG I R N+P P G+ C G R+ + C+ + C
Sbjct: 1920 KCLGPCGSQSIQWSFRSSNNPRPSGRGRQCRGIHRKARRCQTEPC 1964
Score = 57.8 bits (138), Expect = 6e-08
Identities = 55/265 (20%), Positives = 81/265 (30%), Gaps = 63/265 (23%)
Query: 315 PPLCYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPI--------------MPCSN 360
PPLC + W C C C IC+ C + + C
Sbjct: 4212 PPLCLQGTRSRTLGDSWLQGECQRCSCTPEGVICEDTECAVPEAWTLWSSWSDCPVSCGG 4271
Query: 361 ATVPDGECCPRCWPSDSADDGWSP-----------------WSEWTSCSTSCGNGIQQRG 403
C P + P W W CS SCG G+ R
Sbjct: 4272 GNQVRTRACRAAAPHHRSPPCLGPDTQTRQQPCPGLLEACSWGPWGPCSRSCGPGLASRS 4331
Query: 404 RSCDSLNNRCEGS------SVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTC------ 451
SC L + + + + T+ C+ C ++ WS WS W+ CS
Sbjct: 4332 GSCPCLMAKADPTCNSTFLHLDTQGCYSGPC----PEECVWSSWSSWTRCSCRVLVQQRY 4387
Query: 452 -GDGVITRIRLCNSPSPQMNG--KPCEGEARETKACKKDACPINGGWGPWSPWDICSVTC 508
G +R +P +++G +PC C +D+C P + C C
Sbjct: 4388 RHQGPASRGARAGAPCTRLDGHFRPC-----LISNCSEDSCT------PPFEFHACGSPC 4436
Query: 509 GG--GVQKRSRLCNNPTPQFGGKDC 531
G +LC + P G C
Sbjct: 4437 AGLCATHLSHQLCQDLPPCQPGCYC 4461
Score = 48.5 bits (114), Expect = 4e-05
Identities = 67/297 (22%), Positives = 93/297 (31%), Gaps = 89/297 (29%)
Query: 353 CP--IMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLN 410
CP ++ + +P EC CW + +A G + + G+ +Q + C+
Sbjct: 4461 CPKGLLEQAGGCIPPEEC--NCWHTSAAGAGMT---------LAPGDRLQLGCKECE--- 4506
Query: 411 NRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSC----------------------- 447
C + C Q C WS WSP C
Sbjct: 4507 --CRRGELH---CTSQGCQGLLPLSE-WSEWSPCGPCLPPSALAPASRTALEEHWLRDPT 4560
Query: 448 --SVTCGDGVIT---RIRLCNSPSP--QMNGKP--CEGEARETKACKKD-ACPINGGWGP 497
S T + + R RLC P+ G P C + + C ACP + W
Sbjct: 4561 GLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQQRLCPDPGACPDSCQWSL 4620
Query: 498 WSPWDICSVTCGGGVQKRSRL--------CNNPTPQ---FGG--KDCVGDVTENQICNKQ 544
W PW C V C GG + R R C P Q GG +C T +
Sbjct: 4621 WGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTLDCAN 4680
Query: 545 DCPID--------GCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECK 593
CP CL PC G + CPPG +C + C+
Sbjct: 4681 QCPHSCADLWDRVQCLQGPCRPGCR-------------CPPGQLVQDGRCVPISSCR 4724
Score = 46.6 bits (109), Expect = 1e-04
Identities = 101/391 (25%), Positives = 133/391 (34%), Gaps = 86/391 (21%)
Query: 336 CTECHCQNSVTICKKVSCP-IMPCSNATV--PDGECCPRCWPSDSADDGWSPWSE-WTSC 391
C EC C+ C C ++P S + P G C P PS A + E W
Sbjct: 4502 CKECECRRGELHCTSQGCQGLLPLSEWSEWSPCGPCLP---PSALAPASRTALEEHWLRD 4558
Query: 392 STSCGNGI-------QQRGRSC-DSLNNRCEGSSVQTRTCHIQECDKRFKQDGG------ 437
T + Q R R C D R + T + + +R D G
Sbjct: 4559 PTGLSPTLAPLLASEQHRHRLCLDPATGRPWTGAPHLCTAPLSQ--QRLCPDPGACPDSC 4616
Query: 438 -WSHWSPWSSCSVTCGDGVITRIRL--------CNSPSPQ--MNGKPC-EGEARETKACK 485
WS W PWS C V C G R R C P Q NG PC E EA++T
Sbjct: 4617 QWSLWGPWSPCQVPCSGGFRLRWREAEALCGGGCREPWAQESCNGGPCPECEAQDTVFTL 4676
Query: 486 KDA--CPINGG--W-------GPWSPWDICS----VTCGGGVQKRSRLCNNPTP------ 524
A CP + W GP P C V G V S C P+
Sbjct: 4677 DCANQCPHSCADLWDRVQCLQGPCRPGCRCPPGQLVQDGRCVPISSCRCGLPSANASWEL 4736
Query: 525 ------QFGGKDCVGDVTENQICNKQDCPIDG------CLSNPCFAG-VKCTSYPDGSWK 571
Q ++C V E+ +C Q+CP+ G S PC G ++ +G
Sbjct: 4737 APAQAVQLDCQNCT-CVNESLVCPHQECPVLGPWSAWSSCSAPCGGGTMERHRTCEGGPG 4795
Query: 572 CGACPPGYSGNGIQCTDVDECKEVP-----DACFNHNGEHRCENTDPGYNCL--PCPPRF 624
C + +C ++ C E P AC + C + PG C+ PC P
Sbjct: 4796 VAPCQAQDTEQRQEC-NLQPCPECPPGQVLSACAT-SCPCLCWHLQPGAICVQEPCQPGC 4853
Query: 625 TGSQPFGQGVEHATANKQVCKPRNPCTDGTH 655
P GQ + + T C P C H
Sbjct: 4854 --GCPGGQLLHNGT-----CVPPTACPCTQH 4877
Score = 39.7 bits (91), Expect = 0.017
Identities = 53/216 (24%), Positives = 74/216 (34%), Gaps = 68/216 (31%)
Query: 445 SSCSVTCGDGVITRIRLCNSPSPQMNGKP-CEGEARETKACKKDACPINGGWGPWSPWDI 503
S ++CG G C S + + +P C+ + E D C ++ PWS W
Sbjct: 2465 SPSQLSCGSGE------CLSAERRCDLRPDCQDGSDE------DGC-VDCVLAPWSVWSS 2511
Query: 504 CSVTCGGGVQ-KRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKC 562
CS +CG G+ +R L P P G C D +Q C Q CP+ G +
Sbjct: 2512 CSRSCGLGLTFQRQELLRPPLP---GGSCPRDRFRSQSCFVQACPVAGAWA--------- 2559
Query: 563 TSYPDGSWKC-GACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCP 621
W+ G C G H R +C+ P
Sbjct: 2560 ------MWEAWGPCSVSCGGG-------------------HQSRQR--------SCVDPP 2586
Query: 622 PRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDC 657
P+ G+ G E A Q PC+ GT DC
Sbjct: 2587 PKNGGAPCPGASQERAPCGLQ------PCSGGT-DC 2615
Score = 35.8 bits (81), Expect = 0.25
Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 3/58 (5%)
Query: 318 CYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATV---PDGECCPRC 372
C H G +R E W C C C +++T CP+ C V GE C C
Sbjct: 1967 CEHQGQVHRVGERWHGGPCRVCQCLHNLTAHCSPYCPLGSCPQGWVLVEGTGESCCHC 2024
Score = 31.6 bits (70), Expect = 4.6
Identities = 51/204 (25%), Positives = 71/204 (34%), Gaps = 26/204 (12%)
Query: 430 KRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDA- 488
+R Q+G W + C V C G R C Q GKP + E +C
Sbjct: 806 RRCAQEGASPPWRNQTLCPVMCPGG--QEYRECAPACGQHCGKP--EDCGELGSCVAGCN 861
Query: 489 CPINGGWGPWS---PWDICSVTCGGGVQKRS------RLCNNPTPQFGGK-DCVGDVTEN 538
CP+ W P P +C C G ++ + + CN Q G +C +
Sbjct: 862 CPLGLLWDPEGQCVPPSLCP--CQLGARRYAPGSATMKECNRCICQERGLWNCTARHCPS 919
Query: 539 Q-ICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPD 597
Q C ++ G C + S P GS CPPG +DE PD
Sbjct: 920 QAFCPRELVYAPGACLLTCDSPSANHSCPAGSTDGCVCPPG-------TVLLDERCVPPD 972
Query: 598 AC-FNHNGEHRCENTDPGYNCLPC 620
C H+G+ N +C C
Sbjct: 973 LCPCRHSGQWYLPNATIQEDCNVC 996
>gi|115387099 brain-specific angiogenesis inhibitor 2 [Homo sapiens]
Length = 1585
Score = 142 bits (359), Expect = 1e-33
Identities = 73/204 (35%), Positives = 97/204 (47%), Gaps = 9/204 (4%)
Query: 370 PRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDS--LNNRCEGSSVQTRTCHIQE 427
P + + + D WS W+ CS +CG G+Q R RSC S C G +TR C+
Sbjct: 300 PGLYMAQTGDPAAEEWSPWSVCSLTCGQGLQVRTRSCVSSPYGTLCSGPLRETRPCNNSA 359
Query: 428 CDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKD 487
G W W WS CS +CG G +R+R C PQ GK CEG +TK C
Sbjct: 360 T---CPVHGVWEEWGSWSLCSRSCGRGSRSRMRTC--VPPQHGGKACEGPELQTKLCSMA 414
Query: 488 ACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
ACP+ G W W PW CS +C G Q+RSR C+ P + C G +T+ + C+ +CP
Sbjct: 415 ACPVEGQWLEWGPWGPCSTSCANGTQQRSRKCSVAGPAWA--TCTGALTDTRECSNLECP 472
Query: 548 IDGCLSNPCFAGVKCTSYPDGSWK 571
P A C+ D W+
Sbjct: 473 ATDSKWGPWNAWSLCSKTCDTGWQ 496
Score = 126 bits (317), Expect = 1e-28
Identities = 67/206 (32%), Positives = 90/206 (43%), Gaps = 24/206 (11%)
Query: 346 TICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRS 405
T+C PC+N+ CP W W W+ CS SCG G + R R+
Sbjct: 343 TLCSGPLRETRPCNNSAT-----CP-------VHGVWEEWGSWSLCSRSCGRGSRSRMRT 390
Query: 406 C---DSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLC 462
C CEG +QT+ C + C +G W W PW CS +C +G R R C
Sbjct: 391 CVPPQHGGKACEGPELQTKLCSMAACPV----EGQWLEWGPWGPCSTSCANGTQQRSRKC 446
Query: 463 NSPSPQMNGKPCEGEARETKACKKDACPINGG-WGPWSPWDICSVTCGGGVQKRSRLCNN 521
+ P C G +T+ C CP WGPW+ W +CS TC G Q+R R+C
Sbjct: 447 SVAGPAW--ATCTGALTDTRECSNLECPATDSKWGPWNAWSLCSKTCDTGWQRRFRMCQA 504
Query: 522 PTPQFGGKDCVGDVTENQICNKQDCP 547
Q G C G E + C+++ CP
Sbjct: 505 TGTQ--GYPCEGTGEEVKPCSEKRCP 528
>gi|91982767 semaphorin 5B isoform 1 [Homo sapiens]
Length = 1151
Score = 135 bits (340), Expect = 2e-31
Identities = 65/173 (37%), Positives = 87/173 (50%), Gaps = 14/173 (8%)
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQ---RGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQD 435
D G+ PWS W C G+ R RSCDS RC G HI C + +
Sbjct: 609 DGGFGPWSPWQPCEHLDGDNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSR----N 664
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDA-CPINGG 494
G W+ WS W+ CS +CG G R R C++P+P+ G+ C G++RE + C ++ CP+
Sbjct: 665 GAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPIF 724
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
W W W CS CGGG+Q R R C N G C+G E + CN + CP
Sbjct: 725 WASWGSWSKCSSNCGGGMQSRRRACEN------GNSCLGCGVEFKTCNPEGCP 771
Score = 125 bits (314), Expect = 2e-28
Identities = 79/234 (33%), Positives = 101/234 (43%), Gaps = 36/234 (15%)
Query: 383 SPWSEWTSCSTSCGNGIQQ-------RGRSCDSLNNRCEGSSVQTRTCHIQ---ECD--- 429
+PW+ W + + G Q+ R D + +TRTC CD
Sbjct: 777 TPWTPWLPVNVTQGGARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCPADGSGSCDTDA 836
Query: 430 -----------KRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEA 478
GGW+ W PWSSCS C G R R C +P P+ G PC G+A
Sbjct: 837 LVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDA 896
Query: 479 RETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTEN 538
E + C ACP+ G W W+ W CS +CGGG +R+R C +P P G C+G TE
Sbjct: 897 AEYQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEE 956
Query: 539 QICNKQDCPIDGCLSNPCFAGVKCTSYPDG----SWKCGACPPGYS---GNGIQ 585
+C Q CP +G +P KCT DG S C PG S GN Q
Sbjct: 957 ALCATQACP-EGW--SPWSEWSKCTD--DGAQSRSRHCEELLPGSSACAGNSSQ 1005
Score = 116 bits (291), Expect = 1e-25
Identities = 82/243 (33%), Positives = 108/243 (44%), Gaps = 52/243 (21%)
Query: 395 CG-NGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKR-FKQDGGWSHWSPWSSCSVTCG 452
CG +G QQR C +L + S++ T +I C R +DGG+ WSPW C G
Sbjct: 573 CGWDGKQQR---CSTLE---DSSNMSLWTQNITACPVRNVTRDGGFGPWSPWQPCEHLDG 626
Query: 453 DG---VITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCG 509
D + R R C+SP P+ G C G A C + NG W PWS W +CS +CG
Sbjct: 627 DNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSR-----NGAWTPWSSWALCSTSCG 681
Query: 510 GGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGS 569
G Q R R C+NP P+ GG+ CVG E + CN+ + PC + S+ GS
Sbjct: 682 IGFQVRQRSCSNPAPRHGGRICVGKSREERFCNE---------NTPCPVPIFWASW--GS 730
Query: 570 W-KCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQ 628
W KC + G G+Q + CEN G +CL C F
Sbjct: 731 WSKCSS----NCGGGMQ-----------------SRRRACEN---GNSCLGCGVEFKTCN 766
Query: 629 PFG 631
P G
Sbjct: 767 PEG 769
Score = 107 bits (267), Expect = 7e-23
Identities = 100/344 (29%), Positives = 125/344 (36%), Gaps = 47/344 (13%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCST 393
D+ C C+ + C + C + C S + W+PWS W CST
Sbjct: 627 DNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANC--------SRNGAWTPWSSWALCST 678
Query: 394 SCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQ-ECDKRFKQDGGWSHWSPWSSC 447
SCG G Q R RSC + R C G S + R C+ C W+ W WS C
Sbjct: 679 SCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVPI----FWASWGSWSKC 734
Query: 448 SVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVT 507
S CG G+ +R R C NG C G E K C + CP PW+PW +VT
Sbjct: 735 SSNCGGGMQSRRRACE------NGNSCLGCGVEFKTCNPEGCPEVRRNTPWTPWLPVNVT 788
Query: 508 CGGGVQ-KRSRL-CNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSY 565
GG Q +R R C P G TE + CP DG S A V+
Sbjct: 789 QGGARQEQRFRFTCRAPLADPHGLQFGRRRTET-----RTCPADGSGSCDTDALVE-VLL 842
Query: 566 PDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFT 625
GS P SG C + F + C N +P LPC
Sbjct: 843 RSGS----TSPHTVSGGWAAWGPWSSCSRDCELGFRVR-KRTCTNPEPRNGGLPC----- 892
Query: 626 GSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHY 669
G E+ N Q C R + T +A C GHY
Sbjct: 893 ----VGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCGG-GHY 931
Score = 77.4 bits (189), Expect = 7e-14
Identities = 45/141 (31%), Positives = 60/141 (42%), Gaps = 19/141 (13%)
Query: 356 MPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL-----N 410
+PC +C P+ P A WS W+ W+ CS SCG G QR RSC S
Sbjct: 890 LPCVGDAAEYQDCNPQACPVRGA---WSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGE 946
Query: 411 NRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMN 470
+ C G + C Q C + GWS WS WS C+ DG +R R C P
Sbjct: 947 DICLGLHTEEALCATQACPE------GWSPWSEWSKCT---DDGAQSRSRHCEELLP--G 995
Query: 471 GKPCEGEARETKACKKDACPI 491
C G + +++ C P+
Sbjct: 996 SSACAGNSSQSRPCPYSEIPV 1016
>gi|147904700 semaphorin 5A [Homo sapiens]
Length = 1074
Score = 133 bits (335), Expect = 9e-31
Identities = 54/113 (47%), Positives = 69/113 (61%)
Query: 435 DGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGG 494
+G WS W+ WS CS C G+ R R+CN+P P+ G PC G + E + C CP++G
Sbjct: 784 NGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILPCPVDGV 843
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
W WSPW CS TCGGG R+R C+NP P +GG C+G TE +CN Q CP
Sbjct: 844 WSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQPCP 896
Score = 122 bits (305), Expect = 3e-27
Identities = 62/174 (35%), Positives = 86/174 (49%), Gaps = 16/174 (9%)
Query: 373 WPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQE 427
+ + + + WS W+ W+ CS C GI+ R R C++ + C G S++ + C+I
Sbjct: 778 YSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQECNILP 837
Query: 428 CDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKD 487
C DG WS WSPW+ CS TCG G R R C++P+P G C G E C
Sbjct: 838 CPV----DGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGDICLGLHTEEALCNTQ 893
Query: 488 ACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQIC 541
CP + W WS W C + GVQ R+R C P G C G+ TE++ C
Sbjct: 894 PCPES--WSEWSDWSECEAS---GVQVRARQCILLFPM--GSQCSGNTTESRPC 940
Score = 116 bits (291), Expect = 1e-25
Identities = 79/215 (36%), Positives = 101/215 (46%), Gaps = 30/215 (13%)
Query: 404 RSCDSLNNRCEGSSVQTRTCHIQECDKR-FKQDGGWSHWSPWSSCSVTCGDGV---ITRI 459
+ C SL E S+ I C R DG + WSPW+ C+ T G V + R
Sbjct: 511 KKCTSLE---ESLSMTQWEQSISACPTRNLTVDGHFGVWSPWTPCTHTDGSAVGSCLCRT 567
Query: 460 RLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLC 519
R C+SP+PQ G CEG E C + NGGW PW+ W CS TCG G Q R R C
Sbjct: 568 RSCDSPAPQCGGWQCEGPGMEIANCSR-----NGGWTPWTSWSPCSTTCGIGFQVRQRSC 622
Query: 520 NNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSW-KCGACPPG 578
+NPTP+ GG+ CVG E + CN+ C + + G G W +C A
Sbjct: 623 SNPTPRHGGRVCVGQNREERYCNEHLL----CPPHMFWTGW-------GPWERCTA---- 667
Query: 579 YSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDP 613
G GIQ C+ PD C N E++ NT+P
Sbjct: 668 QCGGGIQARR-RICENGPD-CAGCNVEYQSCNTNP 700
Score = 115 bits (287), Expect = 3e-25
Identities = 67/229 (29%), Positives = 106/229 (46%), Gaps = 34/229 (14%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHW 441
W+ W W C+ CG GIQ R R C++ C G +V+ ++C+ C + K+ W+ W
Sbjct: 656 WTGWGPWERCTAQCGGGIQARRRICEN-GPDCAGCNVEYQSCNTNPCPE-LKKTTPWTPW 713
Query: 442 SPWS--------------SCSVTCGDGVITRI-------RLCNSPSPQMNGKPCEGEARE 480
+P + +C D + + R C+S +G +G + +
Sbjct: 714 TPVNISDNGGHYEQRFRYTCKARLADPNLLEVGRQRIEMRYCSSDGT--SGCSTDGLSGD 771
Query: 481 -TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQ 539
+A + A +NG W W+ W CS C G++ R R+CNNP P++GG C+G E Q
Sbjct: 772 FLRAGRYSAHTVNGAWSAWTSWSQCSRDCSRGIRNRKRVCNNPEPKYGGMPCLGPSLEYQ 831
Query: 540 ICNKQDCPIDGCLSNPCFA-GVKCTSYPDG-----SWKCGACPPGYSGN 582
CN CP+DG S C++ KC++ G + C P Y G+
Sbjct: 832 ECNILPCPVDGVWS--CWSPWTKCSATCGGGHYMRTRSCSNPAPAYGGD 878
Score = 104 bits (260), Expect = 4e-22
Identities = 103/421 (24%), Positives = 154/421 (36%), Gaps = 83/421 (19%)
Query: 292 TTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTVDSCTE------CHCQNSV 345
T+L++S+ E A R + H GV WT + T+ C C+
Sbjct: 514 TSLEESLSMTQWEQSISACPTRNLTVDGHFGVW----SPWTPCTHTDGSAVGSCLCRTRS 569
Query: 346 TICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRS 405
C C + C S + GW+PW+ W+ CST+CG G Q R RS
Sbjct: 570 CDSPAPQCGGWQCEGPGMEIANC--------SRNGGWTPWTSWSPCSTTCGIGFQVRQRS 621
Query: 406 CDSLNNR-----CEGSSVQTRTC--HIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITR 458
C + R C G + + R C H+ F W+ W PW C+ CG G+ R
Sbjct: 622 CSNPTPRHGGRVCVGQNREERYCNEHLLCPPHMF-----WTGWGPWERCTAQCGGGIQAR 676
Query: 459 IRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQK---- 514
R+C NG C G E ++C + CP PW+PW +++ GG +
Sbjct: 677 RRICE------NGPDCAGCNVEYQSCNTNPCPELKKTTPWTPWTPVNISDNGGHYEQRFR 730
Query: 515 ---RSRLCNNPTPQFGGKDCVGDVTENQICNK---QDCPIDGCLSNPCFAGVKCTSYPDG 568
++RL + + G + E + C+ C DG + AG +G
Sbjct: 731 YTCKARLADPNLLEVGRQR-----IEMRYCSSDGTSGCSTDGLSGDFLRAGRYSAHTVNG 785
Query: 569 SWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQ 628
+W + QC+ +C N + C N +P Y +PC
Sbjct: 786 AWSAWT-------SWSQCS--RDCSR-----GIRNRKRVCNNPEPKYGGMPC-------- 823
Query: 629 PFGQGVEHATANKQVCKPRNPCTDGTHDC-NKNAKCNYL---GHYSDPMYRCECKPGYAG 684
G +E+ N C DG C + KC+ GHY P Y G
Sbjct: 824 -LGPSLEYQECNILPCP-----VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAPAYGG 877
Query: 685 N 685
+
Sbjct: 878 D 878
Score = 75.5 bits (184), Expect = 3e-13
Identities = 47/142 (33%), Positives = 59/142 (41%), Gaps = 27/142 (19%)
Query: 356 MPCSNATVPDGEC----CPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL-- 409
MPC ++ EC CP D WS WS WT CS +CG G R RSC +
Sbjct: 821 MPCLGPSLEYQECNILPCP-------VDGVWSCWSPWTKCSATCGGGHYMRTRSCSNPAP 873
Query: 410 ---NNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPS 466
+ C G + C+ Q C + WS WS WS C + GV R R C
Sbjct: 874 AYGGDICLGLHTEEALCNTQPCPE------SWSEWSDWSECEAS---GVQVRARQCILLF 924
Query: 467 PQMNGKPCEGEARETKACKKDA 488
P G C G E++ C D+
Sbjct: 925 PM--GSQCSGNTTESRPCVFDS 944
>gi|32261318 unc-5 homolog B [Homo sapiens]
Length = 945
Score = 105 bits (261), Expect = 3e-22
Identities = 48/112 (42%), Positives = 61/112 (54%), Gaps = 4/112 (3%)
Query: 435 DGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGG 494
+GGWS W+ WS CS CG G R R C +P+P G CEG+A + AC CP++G
Sbjct: 246 NGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTAC-TTICPVDGA 304
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDC 546
W WS W CS C RSR C P PQ GG+DC G + +++ C C
Sbjct: 305 WTEWSKWSACSTEC---AHWRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLC 353
Score = 87.4 bits (215), Expect = 7e-17
Identities = 45/117 (38%), Positives = 57/117 (48%), Gaps = 13/117 (11%)
Query: 381 GWSPWSEWTSCSTSCGNGIQQRGRSCDS---LNNR--CEGSSVQTRTCHIQECDKRFKQD 435
GWS W+EW+ CS CG G Q+R R+C + LN CEG + Q C D
Sbjct: 248 GWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTA-----CTTICPVD 302
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPIN 492
G W+ WS WS+CS C R R C +P PQ G+ C G ++K C C N
Sbjct: 303 GAWTEWSKWSACSTECAH---WRSRECMAPPPQNGGRDCSGTLLDSKNCTDGLCMQN 356
Score = 68.9 bits (167), Expect = 3e-11
Identities = 38/103 (36%), Positives = 47/103 (45%), Gaps = 6/103 (5%)
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
+NGGW W+ W CS CG G QKR+R C NP P GG C G + C CP+DG
Sbjct: 245 VNGGWSSWAEWSPCSNRCGRGWQKRTRTCTNPAPLNGGAFCEGQAFQKTACT-TICPVDG 303
Query: 551 C---LSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVD 590
S +C + S +C A PP G T +D
Sbjct: 304 AWTEWSKWSACSTECAHW--RSRECMAPPPQNGGRDCSGTLLD 344
Score = 36.2 bits (82), Expect = 0.19
Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 8/50 (16%)
Query: 379 DDGWSPWSEWTSCSTSCGNGIQQRGRSC-----DSLNNRCEGSSVQTRTC 423
D W+ WS+W++CST C + R R C + C G+ + ++ C
Sbjct: 302 DGAWTEWSKWSACSTECAH---WRSRECMAPPPQNGGRDCSGTLLDSKNC 348
>gi|222352164 nel-like 1 isoform 1 precursor [Homo sapiens]
Length = 810
Score = 103 bits (257), Expect = 1e-21
Identities = 143/673 (21%), Positives = 242/673 (35%), Gaps = 170/673 (25%)
Query: 49 VKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALE 108
V G +S AF +D + L+ R + F +LA+++Q T G +L++
Sbjct: 48 VSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIR 107
Query: 109 RKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLY 168
+HS F + S+G + GK ++ + A GQW + L V L+
Sbjct: 108 ELEHS--YFELESSGLRDEIRYHYIHNGKPRTEALPYRM-ADGQWHKVALSVSASHLLLH 164
Query: 169 IDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILR 228
+DC ++ +D P ++ + + R K G+ F+G++Q+ + +F
Sbjct: 165 VDCNRIYERVIDPPDTNLPPGINLWLGQ-RNQKHGL---FKGIIQDGKIIF--------- 211
Query: 229 NKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLR 288
+ NG YI + +L C +C + S+V + L+
Sbjct: 212 -----------------MPNG--------YIT-QCPNLNHTCP-TCSDFLSLVQGIMDLQ 244
Query: 289 TIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTV-DSCTECHCQNSVTI 347
++ + + +L N C +G+ YR+ + W D C C C++
Sbjct: 245 ELLAKMTAKLNYAETRLSQLEN-CHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVE 303
Query: 348 CKKVSCPIMPCSNATVP---DGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGR 404
C+++SCP + CS ++P G+CC C P C G + + R
Sbjct: 304 CRRMSCPPLNCSPDSLPVHIAGQCCKVCRP---------------KCIYG-GKVLAEGQR 347
Query: 405 SCDSLNNRCEGSSVQ--TRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLC 462
C G + T C C ++ H P + C R+C
Sbjct: 348 ILTKSCRECRGGVLVKITEMCPPLNCSEK-------DHILPENQC-----------CRVC 389
Query: 463 NSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGG-GVQKRSRLCNN 521
+ G C E CK W+ C G VQ S C +
Sbjct: 390 RGHNFCAEGPKC----GENSECKN-----------WNTKATCECKSGYISVQGDSAYCED 434
Query: 522 PTPQFGGKDCVGDVTENQICNKQDCPIDGCLS--NPCFAGVKCTSYPDGSWKCGACPPGY 579
ID C + + C A C + P G ++C C PGY
Sbjct: 435 --------------------------IDECAAKMHYCHANTVCVNLP-GLYRCD-CVPGY 466
Query: 580 -SGNGIQCTDVDECKEVPDACFNHNGEHRCE------NTDPGYNCLPCPPRFTGS----- 627
+ CT+ DEC +G+H C+ NT G++C C P + G+
Sbjct: 467 IRVDDFSCTEHDEC---------GSGQHNCDENAICTNTVQGHSC-TCKPGYVGNGTICR 516
Query: 628 ----QPFGQGVEHATANKQVC----------KPRNPCTDGTHDCNKNAKCNYLGHYSDPM 673
+ G NK VC K + C++G +C+ +++C L +
Sbjct: 517 AFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGW---- 572
Query: 674 YRCECKPGYAGNG 686
Y CEC+ G+ +G
Sbjct: 573 YHCECRSGFHDDG 585
Score = 68.9 bits (167), Expect = 3e-11
Identities = 103/385 (26%), Positives = 134/385 (34%), Gaps = 92/385 (23%)
Query: 411 NRCEGSSVQTRTCHIQECDKRFKQDG----GWSHWSPWSSC-SVTCGDGVITRIRLCNSP 465
N E Q CH C+K + G W C + TC G + R+
Sbjct: 255 NYAETRLSQLENCH---CEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMS--- 308
Query: 466 SPQMNGKPCEGEARETKACKKDACP--INGGWGPWSPWDICSVTC----GGGVQKRSRLC 519
P +N P C K P I GG I + +C GG + K + +C
Sbjct: 309 CPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMC 368
Query: 520 NNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLS-NPCFAGVKCTSYPD-GSWKCGA--- 574
P KD + + ENQ C C N C G KC + +W A
Sbjct: 369 --PPLNCSEKDHI--LPENQCCRV-------CRGHNFCAEGPKCGENSECKNWNTKATCE 417
Query: 575 CPPGY---SGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFG 631
C GY G+ C D+DEC C + C N Y C C P + F
Sbjct: 418 CKSGYISVQGDSAYCEDIDECAAKMHYC---HANTVCVNLPGLYRC-DCVPGYIRVDDFS 473
Query: 632 QGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYL--GHYSDPMYRCECKPGYAGNGII- 688
C + C G H+C++NA C GH C CKPGY GNG I
Sbjct: 474 ------------CTEHDECGSGQHNCDENAICTNTVQGH------SCTCKPGYVGNGTIC 515
Query: 689 ---CGEDTDLDGW---PNENLVCVANAT-YHCKKD---------------NCPNLPN--- 723
C E G PN+ VC + T HC+KD C NLP
Sbjct: 516 RAFCEEGCRYGGTCVAPNK-CVCPSGFTGSHCEKDIDECSEGIIECHNHSRCVNLPGWYH 574
Query: 724 -SGQEDYDKDGI----GDACDDDDD 743
+ + DG G++C D D+
Sbjct: 575 CECRSGFHDDGTYSLSGESCIDIDE 599
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 325 YRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPS--------- 375
YR+ + WT SC +C C C ++CP + C + +GECCPRC
Sbjct: 703 YRSGDNWT-HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITY 761
Query: 376 -------DSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRC 413
DS S WT + C + GR C S++ C
Sbjct: 762 DIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFEC 806
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)
Query: 318 CYHNGVQYRNNEEWTV--DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC 372
C H G N + WT+ D C+ C C++ C++ +C C N + D CCP C
Sbjct: 634 CPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTAC---DCQNPSA-DLFCCPEC 686
>gi|16933525 unc5C [Homo sapiens]
Length = 931
Score = 101 bits (252), Expect = 4e-21
Identities = 46/112 (41%), Positives = 60/112 (53%), Gaps = 4/112 (3%)
Query: 435 DGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGG 494
+GGWS W+ WS C+ CG G R R C +P+P G CEG++ + AC CP++G
Sbjct: 260 NGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIAC-TTLCPVDGR 318
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDC 546
W PWS W C C R R C P P+ GGKDC G V +++ C C
Sbjct: 319 WTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC 367
Score = 86.7 bits (213), Expect = 1e-16
Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 13/114 (11%)
Query: 381 GWSPWSEWTSCSTSCGNGIQQRGRSCDS---LNNR--CEGSSVQTRTCHIQECDKRFKQD 435
GWS W+EW+ C++ CG G Q+R R+C + LN CEG SVQ C D
Sbjct: 262 GWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIA-----CTTLCPVD 316
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
G W+ WS WS+C C R R C +P+P+ GK C+G ++K C C
Sbjct: 317 GRWTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKDCDGLVLQSKNCTDGLC 367
Score = 69.3 bits (168), Expect = 2e-11
Identities = 35/96 (36%), Positives = 44/96 (45%), Gaps = 9/96 (9%)
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
+NGGW W+ W +C+ CG G QKR+R C NP P GG C G + C CP+DG
Sbjct: 259 VNGGWSTWTEWSVCNSRCGRGYQKRTRTCTNPAPLNGGAFCEGQSVQKIACTTL-CPVDG 317
Query: 551 ---CLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNG 583
S G +CT W+ C NG
Sbjct: 318 RWTPWSKWSTCGTECT-----HWRRRECTAPAPKNG 348
Score = 39.7 bits (91), Expect = 0.017
Identities = 34/145 (23%), Positives = 57/145 (39%), Gaps = 23/145 (15%)
Query: 358 CSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNR 412
C +V C C D W+PWS+W++C T C R R C +
Sbjct: 299 CEGQSVQKIACTTLC----PVDGRWTPWSKWSTCGTEC---THWRRRECTAPAPKNGGKD 351
Query: 413 CEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGK 472
C+G +Q++ C DG +P S V G++ + +C + S +
Sbjct: 352 CDGLVLQSKNC----------TDGLCMQTAP-DSDDVALYVGIVIAVIVCLAISVVVALF 400
Query: 473 PCEGEARETKACKKDACPINGGWGP 497
R+ ++ D+ +NGG+ P
Sbjct: 401 VYRKNHRDFESDIIDSSALNGGFQP 425
>gi|209977117 unc-5 homolog D [Homo sapiens]
Length = 953
Score = 99.8 bits (247), Expect = 1e-20
Identities = 53/153 (34%), Positives = 76/153 (49%), Gaps = 5/153 (3%)
Query: 397 NGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVI 456
N I ++ R DS N C +++ + + + +GGWS W+ WS+C+V CG G
Sbjct: 215 NLIIRQARLSDSGNYTCMAANIVAKRRSLSATVVVYV-NGGWSSWTEWSACNVRCGRGWQ 273
Query: 457 TRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRS 516
R R C +P+P G CEG + + C CP++G W WS W +CS C R
Sbjct: 274 KRSRTCTNPAPLNGGAFCEGMSVQKITC-TSLCPVDGSWEVWSEWSVCSPEC---EHLRI 329
Query: 517 RLCNNPTPQFGGKDCVGDVTENQICNKQDCPID 549
R C P P+ GGK C G E++ C C +D
Sbjct: 330 RECTAPPPRNGGKFCEGLSQESENCTDGLCILD 362
Score = 92.4 bits (228), Expect = 2e-18
Identities = 48/114 (42%), Positives = 61/114 (53%), Gaps = 13/114 (11%)
Query: 381 GWSPWSEWTSCSTSCGNGIQQRGRSCDS---LNNR--CEGSSVQTRTCHIQECDKRFKQD 435
GWS W+EW++C+ CG G Q+R R+C + LN CEG SVQ T C D
Sbjct: 254 GWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKIT-----CTSLCPVD 308
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
G W WS WS CS C RIR C +P P+ GK CEG ++E++ C C
Sbjct: 309 GSWEVWSEWSVCSPECEH---LRIRECTAPPPRNGGKFCEGLSQESENCTDGLC 359
Score = 69.3 bits (168), Expect = 2e-11
Identities = 29/60 (48%), Positives = 34/60 (56%), Gaps = 1/60 (1%)
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
+NGGW W+ W C+V CG G QKRSR C NP P GG C G + C CP+DG
Sbjct: 251 VNGGWSSWTEWSACNVRCGRGWQKRSRTCTNPAPLNGGAFCEGMSVQKITCTSL-CPVDG 309
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/94 (27%), Positives = 37/94 (39%), Gaps = 22/94 (23%)
Query: 335 SCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCSTS 394
+CT N C+ +S + C++ CP D W WSEW+ CS
Sbjct: 278 TCTNPAPLNGGAFCEGMSVQKITCTSL-------CP-------VDGSWEVWSEWSVCSPE 323
Query: 395 CGNGIQQRGRSCDSLNNR-----CEGSSVQTRTC 423
C + R R C + R CEG S ++ C
Sbjct: 324 CEH---LRIRECTAPPPRNGGKFCEGLSQESENC 354
>gi|110347423 spondin 1, extracellular matrix protein [Homo sapiens]
Length = 807
Score = 96.7 bits (239), Expect = 1e-19
Identities = 58/174 (33%), Positives = 81/174 (46%), Gaps = 16/174 (9%)
Query: 385 WSEWTSCSTSCGNGIQQRGRSCD---SLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHW 441
W EW CS +CG G+++R R + + C+ + Q C + EC S W
Sbjct: 564 WGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETSQAEKCMMPECHTI---PCLLSPW 620
Query: 442 SPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPW 501
S WS CSVTCG G+ TR R+ S + + C + + + C CPI+ WS W
Sbjct: 621 SEWSDCSVTCGKGMRTRQRMLKSLAELGD---CNEDLEQVEKCMLPECPIDCELTEWSQW 677
Query: 502 DICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNP 555
C+ +CG G R+R+ PQFGG C V ++ C I CL NP
Sbjct: 678 SECNKSCGKGHVIRTRMI-QMEPQFGGAPCPETV------QRKKCRIRKCLRNP 724
Score = 92.4 bits (228), Expect = 2e-18
Identities = 62/202 (30%), Positives = 92/202 (45%), Gaps = 19/202 (9%)
Query: 356 MPCSNATVPDGECC--PRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSL---N 410
+PC + D + C P C D + S W W+ CS SCG G++ R R
Sbjct: 478 VPCPDTQ--DFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDG 535
Query: 411 NRCEGSSVQTRTCHI-QECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCN-SPSPQ 468
+ C + +T C + +EC + W W CS TCG G+ R R+ +P+
Sbjct: 536 SVCTLPTEETEKCTVNEECSP---SSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPA-- 590
Query: 469 MNGKPCEGEARETKACKKDAC-PINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFG 527
+G C+ E + + C C I PWS W CSVTCG G++ R R+ + + G
Sbjct: 591 -DGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKS-LAELG 648
Query: 528 GKDCVGDVTENQICNKQDCPID 549
DC D+ + + C +CPID
Sbjct: 649 --DCNEDLEQVEKCMLPECPID 668
Score = 85.9 bits (211), Expect = 2e-16
Identities = 58/197 (29%), Positives = 75/197 (38%), Gaps = 40/197 (20%)
Query: 383 SPWSEWTSCSTSCGNGIQQRGRSCDSLNNR--CEGSSVQTRTCHIQECDKRFKQDGGWSH 440
SPWSEW+ CS +CG G++ R R SL C Q C + EC D +
Sbjct: 618 SPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPECPI----DCELTE 673
Query: 441 WSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGG-----W 495
WS WS C+ +CG G + R R+ PQ G PC E + K C+ C N W
Sbjct: 674 WSQWSECNKSCGKGHVIRTRMIQM-EPQFGGAPCP-ETVQRKKCRIRKCLRNPSIQKLRW 731
Query: 496 G--------------------------PWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGK 529
PW+ W C+ CGGG+Q+R
Sbjct: 732 REARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFT 791
Query: 530 DCVGDVTENQICNKQDC 546
C D E + CN C
Sbjct: 792 SC-KDKKEIRACNVHPC 807
Score = 76.6 bits (187), Expect = 1e-13
Identities = 57/204 (27%), Positives = 85/204 (41%), Gaps = 16/204 (7%)
Query: 374 PSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCD-SLNNRCEGSSVQTRTCHIQECDKRF 432
P WSPWS +S + G ++QR L+ C + + C C
Sbjct: 440 PETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQ-DFQPCMGPGCSDED 498
Query: 433 KQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKAC--KKDACP 490
S W WS CS++CG G+ +R R P+ +G C ET+ C ++ P
Sbjct: 499 GSTCTMSEWITWSPCSISCGMGMRSRERYVKQ-FPE-DGSVCTLPTEETEKCTVNEECSP 556
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCN-NPTPQFGGKDCVGDVTENQICNKQDCPID 549
+ W WD CS TCG G++KR R+ NP G C + ++ + C +C
Sbjct: 557 SSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPA---DGSMCKAETSQAEKCMMPECHTI 613
Query: 550 GCLSNPCFAGVKCTSYPDGSWKCG 573
CL +P + + D S CG
Sbjct: 614 PCLLSP------WSEWSDCSVTCG 631
Score = 42.4 bits (98), Expect = 0.003
Identities = 32/147 (21%), Positives = 54/147 (36%), Gaps = 33/147 (22%)
Query: 374 PSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGS----SVQTRTCHIQEC- 428
P D + WS+W+ C+ SCG G R R + + G+ +VQ + C I++C
Sbjct: 663 PECPIDCELTEWSQWSECNKSCGKGHVIRTRMI-QMEPQFGGAPCPETVQRKKCRIRKCL 721
Query: 429 ------------------DKRFKQDGGWSH--------WSPWSSCSVTCGDGVITRIRLC 462
++ K++ W+ WS C+ CG G+ R
Sbjct: 722 RNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTV 781
Query: 463 NSPSPQMNGKPCEGEARETKACKKDAC 489
C+ + +E +AC C
Sbjct: 782 KKRFKSSQFTSCK-DKKEIRACNVHPC 807
>gi|222352166 nel-like 1 isoform 2 precursor [Homo sapiens]
Length = 763
Score = 94.0 bits (232), Expect = 8e-19
Identities = 142/660 (21%), Positives = 231/660 (35%), Gaps = 131/660 (19%)
Query: 49 VKGPDPSSPAFRIEDANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLALE 108
V G +S AF +D + L+ R + F +LA+++Q T G +L++
Sbjct: 48 VSGMHNASKAFLFQDIEREIHAAPHVSEKLIQLFRNKSEFTILATVQQKPSTSGVILSIR 107
Query: 109 RKDHSGQVFSVVSNGKAGTLDLSLTVQGKQHVVSVEEALLATGQWKSITLFVQEDRAQLY 168
+HS F + S+G + GK ++ + A GQW + L V L+
Sbjct: 108 ELEHS--YFELESSGLRDEIRYHYIHNGKPRTEALPYRM-ADGQWHKVALSVSASHLLLH 164
Query: 169 IDCEKMENAELDVPIQSVFTRDLASIARLRIAKGGVNDNFQGVLQNVRFVFGTTPEDILR 228
+DC ++ +D P ++ + + R K G+ F+G++Q+ + +F
Sbjct: 165 VDCNRIYERVIDPPDTNLPPGINLWLGQ-RNQKHGL---FKGIIQDGKIIF--------- 211
Query: 229 NKGCSSSTSVLLTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLELRGLR 288
+ NG YI + +L C +C + S+V + L+
Sbjct: 212 -----------------MPNG--------YIT-QCPNLNHTCP-TCSDFLSLVQGIMDLQ 244
Query: 289 TIVTTLQDSIRKVTEENKELANELRRPPLCYHNGVQYRNNEEWTV-DSCTECHCQNSVTI 347
++ + + +L N C +G+ YR+ + W D C C C++
Sbjct: 245 ELLAKMTAKLNYAETRLSQLEN-CHCEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVE 303
Query: 348 CKKVSCPIMPCSNATVP---DGECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGR 404
C+++SCP + CS ++P G+CC C P C G + + R
Sbjct: 304 CRRMSCPPLNCSPDSLPVHIAGQCCKVCRP---------------KCIYG-GKVLAEGQR 347
Query: 405 SCDSLNNRCEGSSVQ--TRTCHIQECDKRFKQDGGWSHWSPWSSCSVTC-GDGVITRIRL 461
C G + T C C ++ H P + C C G
Sbjct: 348 ILTKSCRECRGGVLVKITEMCPPLNCSEK-------DHILPENQCCRVCRGHNFCAEGPK 400
Query: 462 CNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNN 521
C S N + T CK + G D C+ + +C N
Sbjct: 401 CGENSECKN-----WNTKATCECKSGYISVQGDSAYCEDIDECAAKM--HYCHANTVCVN 453
Query: 522 PTPQFGGKDCVGDV--TENQICNKQD-CPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPG 578
P DCV ++ C + D C G + C CT+ G C C PG
Sbjct: 454 -LPGLYRCDCVPGYIRVDDFSCTEHDEC---GSGQHNCDENAICTNTVQGH-SC-TCKPG 507
Query: 579 YSGNGIQC--------------------------------TDVDECKEVPDACFNHNGEH 606
Y GNG C D+DEC C+N +
Sbjct: 508 YVGNGTICRAFCEEGCRYGGTCVAPNKCVCPSGFTGSHCEKDIDECALRTHTCWN---DS 564
Query: 607 RCENTDPGYNCL-PCPPRFTGSQPFGQGVEHA----TANKQVCKPRNPCTDGTHDCNKNA 661
C N G++CL P P +G P G++H T + C + C DG C + A
Sbjct: 565 ACINLAGGFDCLCPSGPSCSGDCPHEGGLKHNGQVWTLKEDRCSVCS-CKDGKIFCRRTA 623
Score = 67.8 bits (164), Expect = 6e-11
Identities = 93/335 (27%), Positives = 119/335 (35%), Gaps = 69/335 (20%)
Query: 411 NRCEGSSVQTRTCHIQECDKRFKQDG----GWSHWSPWSSC-SVTCGDGVITRIRLCNSP 465
N E Q CH C+K + G W C + TC G + R+
Sbjct: 255 NYAETRLSQLENCH---CEKTCQVSGLLYRDQDSWVDGDHCRNCTCKSGAVECRRMS--- 308
Query: 466 SPQMNGKPCEGEARETKACKKDACP--INGGWGPWSPWDICSVTC----GGGVQKRSRLC 519
P +N P C K P I GG I + +C GG + K + +C
Sbjct: 309 CPPLNCSPDSLPVHIAGQCCKVCRPKCIYGGKVLAEGQRILTKSCRECRGGVLVKITEMC 368
Query: 520 NNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLS-NPCFAGVKCTSYPD-GSWKCGA--- 574
P KD + + ENQ C C N C G KC + +W A
Sbjct: 369 --PPLNCSEKDHI--LPENQCCRV-------CRGHNFCAEGPKCGENSECKNWNTKATCE 417
Query: 575 CPPGY---SGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFG 631
C GY G+ C D+DEC C + C N Y C C P + F
Sbjct: 418 CKSGYISVQGDSAYCEDIDECAAKMHYC---HANTVCVNLPGLYRC-DCVPGYIRVDDFS 473
Query: 632 QGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYL--GHYSDPMYRCECKPGYAGNGII- 688
C + C G H+C++NA C GH C CKPGY GNG I
Sbjct: 474 ------------CTEHDECGSGQHNCDENAICTNTVQGH------SCTCKPGYVGNGTIC 515
Query: 689 ---CGEDTDLDGW---PNENLVCVANAT-YHCKKD 716
C E G PN+ VC + T HC+KD
Sbjct: 516 RAFCEEGCRYGGTCVAPNK-CVCPSGFTGSHCEKD 549
Score = 55.1 bits (131), Expect = 4e-07
Identities = 30/105 (28%), Positives = 42/105 (40%), Gaps = 17/105 (16%)
Query: 325 YRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPS--------- 375
YR+ + WT SC +C C C ++CP + C + +GECCPRC
Sbjct: 656 YRSGDNWT-HSCQQCRCLEGEVDCWPLTCPNLSCEYTAILEGECCPRCVSDPCLADNITY 714
Query: 376 -------DSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRC 413
DS S WT + C + GR C S++ C
Sbjct: 715 DIRKTCLDSYGVSRLSGSVWTMAGSPCTTCKCKNGRVCCSVDFEC 759
Score = 41.6 bits (96), Expect = 0.004
Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 6/57 (10%)
Query: 318 CYHNGVQYRNNEEWTV--DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC 372
C H G N + WT+ D C+ C C++ C++ +C C N + D CCP C
Sbjct: 587 CPHEGGLKHNGQVWTLKEDRCSVCSCKDGKIFCRRTAC---DCQNPSA-DLFCCPEC 639
>gi|157427675 ADAM metallopeptidase with thrombospondin type 1
motif, 4 preproprotein [Homo sapiens]
Length = 837
Score = 88.2 bits (217), Expect = 4e-17
Identities = 55/152 (36%), Positives = 70/152 (46%), Gaps = 20/152 (13%)
Query: 426 QECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSP-SPQMNGKPCEGEARETKAC 484
++C F D P ++ C G + +C + SP +G PC G A+ AC
Sbjct: 447 RQCQLTFGPDSRHCPQLPPPCAALWCS-GHLNGHAMCQTKHSPWADGTPC-GPAQ---AC 501
Query: 485 KKDAC-----------PINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVG 533
C P GGWGPW PW CS TCGGGVQ SR C P P+ GGK C G
Sbjct: 502 MGGRCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRPVPRNGGKYCEG 561
Query: 534 DVTENQICNKQDCPIDGCLSNPCFAGVKCTSY 565
T + CN +DCP L+ F +C +Y
Sbjct: 562 RRTRFRSCNTEDCPTGSALT---FREEQCAAY 590
Score = 52.8 bits (125), Expect = 2e-06
Identities = 53/205 (25%), Positives = 76/205 (37%), Gaps = 54/205 (26%)
Query: 357 PCSNATVPDGECCPRCWPSDSADD-------GWSPWSEWTSCSTSCGNGIQQRGRSCDSL 409
PC A G RC D D GW PW W CS +CG G+Q R C
Sbjct: 494 PCGPAQACMGG---RCLHMDQLQDFNIPQAGGWGPWGPWGDCSRTCGGGVQFSSRDCTRP 550
Query: 410 NNR-----CEGSSVQTRTCHIQECDK------RFKQDGGWSH-------------W---- 441
R CEG + R+C+ ++C R +Q ++H W
Sbjct: 551 VPRNGGKYCEGRRTRFRSCNTEDCPTGSALTFREEQCAAYNHRTDLFKSFPGPMDWVPRY 610
Query: 442 ---SPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGW--- 495
+P C +TC + + ++G PC ++ + C + C I+ G
Sbjct: 611 TGVAPQDQCKLTCQAQALGYYYVLE--PRVVDGTPCSPDS--SSVCVQGRC-IHAGCDRI 665
Query: 496 -GPWSPWDICSVTCGG---GVQKRS 516
G +D C V CGG G K+S
Sbjct: 666 IGSKKKFDKCMV-CGGDGSGCSKQS 689
>gi|51558724 ADAM metallopeptidase with thrombospondin type 1 motif,
12 preproprotein [Homo sapiens]
Length = 1594
Score = 85.5 bits (210), Expect = 3e-16
Identities = 37/81 (45%), Positives = 47/81 (58%), Gaps = 4/81 (4%)
Query: 491 INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
I GGWG WSPW CS TCG GVQ RLCNNP P+FGGK C G+ ++CN C +
Sbjct: 541 IPGGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEA 600
Query: 551 CLSNPCFAGVKCTSYPDGSWK 571
P F ++C+ + +K
Sbjct: 601 ----PTFRQMQCSEFDTVPYK 617
Score = 70.9 bits (172), Expect = 7e-12
Identities = 28/54 (51%), Positives = 33/54 (61%)
Query: 436 GGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
GGW WSPWS CS TCG GV + RLCN+P P+ GK C GE + + C C
Sbjct: 543 GGWGRWSPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPC 596
Score = 64.7 bits (156), Expect = 5e-10
Identities = 65/238 (27%), Positives = 96/238 (40%), Gaps = 45/238 (18%)
Query: 331 WTVDSCTECHCQNSV-TICKKVSCPIMPCSN-ATVPDGECCPRCWPSDSADDGWSPWSEW 388
W V + +EC + ++V C S+ A + + RC A GW W
Sbjct: 1317 WIVGNWSECSTTCGLGAYWRRVECSTQMDSDCAAIQRPDPAKRCHLRPCA--GWKV-GNW 1373
Query: 389 TSCSTSCGNGIQQRGRSC-DSLNNR------CEGSS----VQTRTCHIQECDKRFKQDGG 437
+ CS +C G + R C DS ++R C+ + + +C+ + C+
Sbjct: 1374 SKCSRNCSGGFKIREIQCVDSRDHRNLRPFHCQFLAGIPPPLSMSCNPEPCE-------A 1426
Query: 438 WSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGP 497
W PWS CS +CG GV R C +P T +C + C W
Sbjct: 1427 WQV-EPWSQCSRSCGGGVQERGVFCPGGLCDWTKRPTS-----TMSCNEHLCC---HWAT 1477
Query: 498 WSPWDICSVTCGGGVQKRSRLCNNPTPQFGGK-----DCVGD----VTENQICNKQDC 546
+ WD+CS +CGGG QKR+ C P G K C+ D E + CN+Q C
Sbjct: 1478 GN-WDLCSTSCGGGFQKRTVQC---VPSEGNKTEDQDQCLCDHKPRPPEFKKCNQQAC 1531
Score = 63.2 bits (152), Expect = 1e-09
Identities = 52/182 (28%), Positives = 76/182 (41%), Gaps = 33/182 (18%)
Query: 385 WSEWTSCSTSCGNGIQQRGRSCDSLNNR------CEGSSV---QTRTCHIQECDKRFKQD 435
+ WT CS +CG GI+++ C C+ + + + CH + C R+
Sbjct: 830 YGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKCHEKACPPRW--- 886
Query: 436 GGWSHWSPWSSCSVTCGD-GVITRIRLCN----SPSPQMNGKPCEG--EARETKACKKDA 488
W+ W +CS TCG G R LC S + C+ + + +C +D
Sbjct: 887 --WA--GEWEACSATCGPHGEKKRTVLCIQTMVSDEQALPPTDCQHLLKPKTLLSCNRDI 942
Query: 489 -CPINGGWGPWSPWDICSVTCGGGVQKRSRLC--NNPTPQFGGKDCVGDVTENQICNKQD 545
CP + G WS CSV+CGGGV+ RS C N+ P D +C Q
Sbjct: 943 LCPSDWTVGNWSE---CSVSCGGGVRIRSVTCAKNHDEP----CDVTRKPNSRALCGLQQ 995
Query: 546 CP 547
CP
Sbjct: 996 CP 997
Score = 48.9 bits (115), Expect = 3e-05
Identities = 43/193 (22%), Positives = 68/193 (35%), Gaps = 44/193 (22%)
Query: 341 CQNSVTICKKVSCPIMPCSNATVP---DG-ECCPRCW-----------PSDSADDGWSPW 385
CQ +C+ + C + + + DG +C + W +S GW W
Sbjct: 489 CQEVENVCQTLWCSVKGFCRSKLDAAADGTQCGEKKWCMAGKCITVGKKPESIPGGWGRW 548
Query: 386 SEWTSCSTSCGNGIQQRGRSCDSLNNR-----CEGSSVQTRTCHIQECDKR---FKQ--- 434
S W+ CS +CG G+Q R C++ + C G + R C++ C F+Q
Sbjct: 549 SPWSHCSRTCGAGVQSAERLCNNPEPKFGGKYCTGERKRYRLCNVHPCRSEAPTFRQMQC 608
Query: 435 --------DGGWSHW----SPWSSCSVTCG--DGVITRIRLCNSPSPQMNGKPCEGEARE 480
HW +P C + C DG + L ++G PC
Sbjct: 609 SEFDTVPYKNELYHWFPIFNPAHPCELYCRPIDGQFSEKML----DAVIDGTPCFEGGNS 664
Query: 481 TKACKKDACPING 493
C C + G
Sbjct: 665 RNVCINGICKMVG 677
Score = 46.6 bits (109), Expect = 1e-04
Identities = 31/96 (32%), Positives = 43/96 (44%), Gaps = 8/96 (8%)
Query: 429 DKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQM-NGKPCEGEAR---ETKAC 484
D +Q + + W+ CSVTCG G+ + C M C+ E + K C
Sbjct: 818 DNDVEQQMYFWQYGHWTECSVTCGTGIRRQTAHCIKKGRGMVKATFCDPETQPNGRQKKC 877
Query: 485 KKDACPINGGWGPWSPWDICSVTCG-GGVQKRSRLC 519
+ ACP G W+ CS TCG G +KR+ LC
Sbjct: 878 HEKACPPRWWAG---EWEACSATCGPHGEKKRTVLC 910
>gi|56121815 ADAM metallopeptidase with thrombospondin type 1 motif,
10 preproprotein [Homo sapiens]
Length = 1103
Score = 84.0 bits (206), Expect = 8e-16
Identities = 37/96 (38%), Positives = 49/96 (51%), Gaps = 8/96 (8%)
Query: 460 RLCNSPSPQMNGKPCEGEARETKACKKDACP--------INGGWGPWSPWDICSVTCGGG 511
R + P G C+ + C K C ++G WGPW+PW CS TCGGG
Sbjct: 507 RCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCSRTCGGG 566
Query: 512 VQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP 547
V SR C++P P GGK C+G+ ++ CN DCP
Sbjct: 567 VSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCP 602
Score = 76.6 bits (187), Expect = 1e-13
Identities = 41/102 (40%), Positives = 49/102 (48%), Gaps = 17/102 (16%)
Query: 406 CDSLNNRC--------EGSSVQTRTCHIQECDKRF---------KQDGGWSHWSPWSSCS 448
C S +NRC EG+ QT T C KR DG W W+PW CS
Sbjct: 501 CLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFGSRPEGVDGAWGPWTPWGDCS 560
Query: 449 VTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACP 490
TCG GV + R C+SP P + GK C GE R ++C D CP
Sbjct: 561 RTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDDCP 602
Score = 58.9 bits (141), Expect = 3e-08
Identities = 37/123 (30%), Positives = 52/123 (42%), Gaps = 15/123 (12%)
Query: 319 YHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMP---CSNATVPDGECCPR-CWP 374
+ +GV+ R + V C+E C + C S P C T+ G C R C P
Sbjct: 481 FQHGVKSRQCKYGEV--CSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVP 538
Query: 375 SDSADDG----WSPWSEWTSCSTSCGNGIQQRGRSCDSL-----NNRCEGSSVQTRTCHI 425
S +G W PW+ W CS +CG G+ R CDS C G + R+C+
Sbjct: 539 FGSRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNT 598
Query: 426 QEC 428
+C
Sbjct: 599 DDC 601
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/184 (26%), Positives = 69/184 (37%), Gaps = 34/184 (18%)
Query: 388 WTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQ-----------TRTCHIQECDKRFKQDG 436
W+ CS SC G++ R C + E ++ CH C
Sbjct: 893 WSLCSRSCDAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPE----- 947
Query: 437 GWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKP--CEGEAR--ETKACKKDACP-- 490
W+ WS C+ +CG G+ R+ LC S + P C A+ T C CP
Sbjct: 948 -WAALD-WSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPA 1005
Query: 491 --INGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGK--DCVGDVTENQICNKQDC 546
+ G WG CS CG G ++RS C + T Q + + + T Q K D
Sbjct: 1006 RWVAGEWGE------CSAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDS 1059
Query: 547 PIDG 550
P G
Sbjct: 1060 PTPG 1063
Score = 54.3 bits (129), Expect = 7e-07
Identities = 60/262 (22%), Positives = 91/262 (34%), Gaps = 61/262 (23%)
Query: 385 WSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSV-------------QTRTCHIQECDKR 431
++ WT CS C G Q + C N+ + S+V + R C+ + C
Sbjct: 831 YAPWTKCSAQCAGGSQVQAVEC---RNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPD 887
Query: 432 FKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPI 491
+ WS CS +C GV +R +C Q E +A + AC + P+
Sbjct: 888 WVVGN-------WSLCSRSCDAGVRSRSVVC-----QRRVSAAEEKALDDSACPQPRPPV 935
Query: 492 -NGGWGPWSP-------WDICSVTCGGGVQKRSRLCNNPTPQ--FGGKDC--VGDVTENQ 539
GP P W C+ +CG G++ R LC + + C
Sbjct: 936 LEACHGPTCPPEWAALDWSECTPSCGPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATM 995
Query: 540 ICNKQDCPIDGCLSNPCFAGVKCTSYPDGSW-KCGA-CPPGYSGNGIQCTD-----VDEC 592
CN + CP + G W +C A C G ++CT EC
Sbjct: 996 RCNLRRCP--------------PARWVAGEWGECSAQCGVGQRQRSVRCTSHTGQASHEC 1041
Query: 593 KEVPDACFNHNGEHRCENTDPG 614
E E +C++ PG
Sbjct: 1042 TEALRPPTTQQCEAKCDSPTPG 1063
Score = 49.3 bits (116), Expect = 2e-05
Identities = 39/170 (22%), Positives = 61/170 (35%), Gaps = 27/170 (15%)
Query: 440 HWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKP--CEGEARETK---ACKKDACPINGG 494
H++PW+ CS C G + C + P C ++ K AC + CP +
Sbjct: 830 HYAPWTKCSAQCAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWV 889
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCP------I 548
G WS +CS +C GV+ RS +C E + + CP +
Sbjct: 890 VGNWS---LCSRSCDAGVRSRSVVCQRRV----------SAAEEKALDDSACPQPRPPVL 936
Query: 549 DGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDA 598
+ C C + + + CG PG + C D +P A
Sbjct: 937 EACHGPTCPPEWAALDWSECTPSCG---PGLRHRVVLCKSADHRATLPPA 983
Score = 47.0 bits (110), Expect = 1e-04
Identities = 44/180 (24%), Positives = 65/180 (36%), Gaps = 29/180 (16%)
Query: 341 CQNSVTICKKVSCPIMPCSNATVPDGECC--PRCWPSDSADDGWSPWSEWTSCSTSCGNG 398
CQ V+ ++ + C P E C P C P +A D W+ C+ SCG G
Sbjct: 911 CQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALD-------WSECTPSCGPG 963
Query: 399 IQQRGRSCDSLNNRC---------EGSSVQTRTCHIQECDKRFKQDGGWSHW--SPWSSC 447
++ R C S ++R T C+++ C + W W C
Sbjct: 964 LRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPP--------ARWVAGEWGEC 1015
Query: 448 SVTCGDGVITRIRLCNSPSPQMNGKPCEG-EARETKACKKDACPINGGWGPWSPWDICSV 506
S CG G R C S + Q + + E T+ C+ G GP D+ V
Sbjct: 1016 SAQCGVGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKV 1075
>gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens]
Length = 1503
Score = 84.0 bits (206), Expect = 8e-16
Identities = 107/417 (25%), Positives = 140/417 (33%), Gaps = 91/417 (21%)
Query: 318 CYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDS 377
C NG Y N E ++ D+CT C C C+ SC + C + P GECCP C
Sbjct: 138 CSQNGQTYGNGETFSPDACTTCRCLTGAVQCQGPSCSELNCLESCTPPGECCPICCTEGG 197
Query: 378 ADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGG 437
+ W EWT+ C R C RC +Q C +EC
Sbjct: 198 SH--WEHGQEWTTPGDPC--------RIC-----RCLEGHIQ---CRQRECASLCPYP-- 237
Query: 438 WSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCE--GEARETKACKKDACPINGGW 495
+ P + C V DG R S P +G PC A + C+ CP
Sbjct: 238 -ARPLPGTCCPVC--DGCFLNGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCR 294
Query: 496 GPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKD-CV------GDVTENQICNKQDCPI 548
P C C G + + + T + + CV G+V+ C +Q+CP+
Sbjct: 295 HPGKIPGQCCPVCDGCEYQGHQYQSQETFRLQERGLCVRCSCQAGEVS----CEEQECPV 350
Query: 549 DGC--------------LSNPCFA--------GVKCTS--YPDGSWKCGA--CPPGYSGN 582
C L FA G CT+ DG KCGA CPP +
Sbjct: 351 TPCALPASGRQLCPACELDGEEFAEGVQWEPDGRPCTACVCQDGVPKCGAVLCPPAPCQH 410
Query: 583 GIQCTDVDECKEVPDACFNH-----NGE---------HRCENTDPGYNC--LPCPPRFTG 626
Q C D+C H NG+ H C D C + CPP
Sbjct: 411 PTQ--PPGACCPSCDSCTYHSQVYANGQNFTDADSPCHACHCQDGTVTCSLVDCPPTTCA 468
Query: 627 SQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYA 683
G G C PR C D + H DP C C+ G+A
Sbjct: 469 RPQSGPG---------QCCPR--CPDCILEEEVFVDGESFSHPRDPCQECRCQEGHA 514
Score = 57.4 bits (137), Expect = 8e-08
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 318 CYHNGVQYRNNEEWTVDSCTECHCQNSVTICKKVSCPIMPCSNATVP---DGECCPRCWP 374
C H G + + E WTVD+CT C C C+ C + C P G CCPRC P
Sbjct: 1086 CVHQGREVASGERWTVDTCTSCSCMAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLP 1145
Score = 52.8 bits (125), Expect = 2e-06
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 318 CYHNGVQYRNNEEWT--VDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPS 375
C G ++++ EE+ SC C CQ C ++ CP +PC G CCPRC
Sbjct: 837 CLSQGREHQDGEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRGC 896
Query: 376 DSADDGWSPWSEWTSCSTSCGNGIQQRG 403
+ + S W ++C + + G
Sbjct: 897 LAHGEEHPEGSRWVPPDSACSSCVCHEG 924
Score = 47.8 bits (112), Expect = 6e-05
Identities = 84/388 (21%), Positives = 131/388 (33%), Gaps = 85/388 (21%)
Query: 318 CYHNGVQYRNNEEWTV--DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCW-- 373
C + G Y +N+E+ + C C C C + C CS+ +P G CCP C
Sbjct: 719 CEYLGESYLSNQEFPDPREPCNLCTCLGGFVTCGRRPCEPPGCSHPLIPSGHCCPTCQGC 778
Query: 374 --------PSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHI 425
++ D P +C G+ Q+ +L CH
Sbjct: 779 RYHGVTTASGETLPDPLDPTCSLCTCQE--GSMRCQKKPCPPALCPHPSPGPCFCPVCHS 836
Query: 426 QECDKRFKQDGGWSHWSPWSSCS-VTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKAC 484
R QDG P SC C G ++ +RL Q PC+ + E +C
Sbjct: 837 CLSQGREHQDGE-EFEGPAGSCEWCRCQAGQVSCVRL------QCPPLPCKLQVTERGSC 889
Query: 485 --KKDACPINGGWGP----WSPWD--ICSVTCGGGVQKRSR---LCNNPTPQFGGKDCVG 533
+ C +G P W P D S C GV +R + + P+ G DC
Sbjct: 890 CPRCRGCLAHGEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHDCCP 949
Query: 534 DVTENQICNKQDCPIDGCL--SNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDE 591
++ + ++ P + ++PC + C P+G PP + QC +
Sbjct: 950 QCSDCEHEGRKYEPGESFQPGADPCEVCI-CEPQPEG-------PPSLRCHRRQCPSL-- 999
Query: 592 CKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCT 651
+ CPP SQ G +H C P C
Sbjct: 1000 --------------------------VGCPP----SQLLPPGPQH-------CCP--TCA 1020
Query: 652 DGTHDCNKNAKCNYLGHYSDPMYRCECK 679
+ +C++ + L DP Y C+C+
Sbjct: 1021 EALSNCSEGLLGSELAP-PDPCYTCQCQ 1047
Score = 40.0 bits (92), Expect = 0.013
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 5/61 (8%)
Query: 315 PPLCYHNGVQYRNNEEWTV---DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPR 371
P C G + ++E+ D C C C + C+++ CP PC++ G CCP
Sbjct: 601 PAGCPRPGAAHARHQEYFSPPGDPCRRCLCLDGSVSCQRLPCPPAPCAHPR--QGPCCPS 658
Query: 372 C 372
C
Sbjct: 659 C 659
Score = 40.0 bits (92), Expect = 0.013
Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 14/89 (15%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPC--SNATVPDGECCPRC-WPSDS---------ADDG 381
D C C CQ+ +C +CP + C S P G CCP C P+ S + +
Sbjct: 1039 DPCYTCQCQDLTWLCIHQACPELSCPLSERHTPPGSCCPVCRAPTQSCVHQGREVASGER 1098
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLN 410
W+ TSCS G ++ + + C L+
Sbjct: 1099 WTV-DTCTSCSCMAGT-VRCQSQRCSPLS 1125
Score = 39.3 bits (90), Expect = 0.022
Identities = 17/57 (29%), Positives = 25/57 (43%), Gaps = 2/57 (3%)
Query: 318 CYHNGVQYRNNEEWT--VDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRC 372
C G +Y + ++ D C C C + C C +PC + GECCP+C
Sbjct: 542 CAFGGKEYPSGADFPHPSDPCRLCRCLSGNVQCLARRCVPLPCPEPVLLPGECCPQC 598
Score = 37.0 bits (84), Expect = 0.11
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 2/37 (5%)
Query: 334 DSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCP 370
D C EC CQ C+ CP PC++ G CCP
Sbjct: 502 DPCQECRCQEGHAHCQPRPCPRAPCAHPL--PGTCCP 536
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 83.6 bits (205), Expect = 1e-15
Identities = 79/273 (28%), Positives = 108/273 (39%), Gaps = 71/273 (26%)
Query: 467 PQMNGKPCEGEARETKACKKDA-CPINGGW-------------GPWSPWDICSVTCGGGV 512
P ++G PC R T+ ++A C GW GP + +C + G
Sbjct: 42 PCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGT 101
Query: 513 QKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKC 572
+ S C F G DC P D CLS+PC G +C+ PDG + C
Sbjct: 102 ARFSCRCPRG---FRGPDC-------------SLP-DPCLSSPCAHGARCSVGPDGRFLC 144
Query: 573 GACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQ 632
+CPPGY G + +DVDEC+ V + C H G C NT + C CP +TG
Sbjct: 145 -SCPPGYQGRSCR-SDVDECR-VGEPC-RHGG--TCLNTPGSFRC-QCPAGYTG------ 191
Query: 633 GVEHATANKQVCK-PRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECKPGYAGNGIICGE 691
+C+ P PC C C G D Y C C PG+ G
Sbjct: 192 ---------PLCENPAVPCAPS--PCRNGGTCRQSG---DLTYDCACLPGFEGQNC---- 233
Query: 692 DTDLDGWPNENLV----CVANA-TYHCKKDNCP 719
+ ++D P + CV TY+C+ CP
Sbjct: 234 EVNVDDCPGHRCLNGGTCVDGVNTYNCQ---CP 263
Score = 62.0 bits (149), Expect = 3e-09
Identities = 109/447 (24%), Positives = 153/447 (34%), Gaps = 126/447 (28%)
Query: 353 CPIMPCSNAT---VPDGECC--------PRCWPSDSADDGWS-PWSEWTSCST------- 393
C PCS+ P G C PRC S + D S P +CS+
Sbjct: 699 CAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHC 758
Query: 394 SCGNGIQQRGRSCDSLN----------NRCEGSSVQTRTCHIQE------CDKRFKQDGG 437
+C G+Q GR C+ L+ RCE + Q C + C + + G
Sbjct: 759 TCPPGVQ--GRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAG 816
Query: 438 WSHWSPWSSC-------SVTCGDGVI-----TRIRLCNSPSPQMNGKPCE-GEARETKAC 484
+ P C S TC G I C+ P+P +NG C+ G + +C
Sbjct: 817 PAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCD-PNPCLNGGSCQDGVGSFSCSC 875
Query: 485 KKDACPINGGWGPWSPWDI---CSVTCGGGV---QKRSRLCNNPTPQFGGKDCVGDVTEN 538
+ G GP D+ S CG G S C P P +GG C D+ +
Sbjct: 876 ------LPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCP-PGYGGFHCEQDLPD- 927
Query: 539 QICNKQDC-----PIDG-----CLSNPCFAGVKCTSYPDGSWK--------CGACPPGYS 580
C+ C +DG CL P + G C D C A PG+
Sbjct: 928 --CSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFR 985
Query: 581 GNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTG------SQPFGQGV 634
++ +C+ + D C ++ G CL CPP ++G S P +
Sbjct: 986 CTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCL-CPPGWSGRLCDIRSLPCREAA 1044
Query: 635 EHATAN-KQVCKPRNPCTD--------------GTH-----------DCNKNAKCN-YLG 667
+Q+C+ C D G+H C C Y+G
Sbjct: 1045 AQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMG 1104
Query: 668 HYSDPMYRCECKPGYAGNGIICGEDTD 694
Y CEC PGY NG C +D D
Sbjct: 1105 GYM-----CECLPGY--NGDNCEDDVD 1124
Score = 58.2 bits (139), Expect = 5e-08
Identities = 62/224 (27%), Positives = 88/224 (39%), Gaps = 42/224 (18%)
Query: 472 KPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQ----KRSRLCNNPTPQFG 527
+PC+ R + CP GW DI S+ C + +LC Q G
Sbjct: 1007 QPCQNGGRCVQTGAYCLCP--PGWSG-RLCDIRSLPCREAAAQIGVRLEQLC-----QAG 1058
Query: 528 GKDCVGDVTENQICNKQ------DCPIDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSG 581
G+ D + +C + + +D CL+ PC G C Y G + C C PGY+G
Sbjct: 1059 GQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM-GGYMC-ECLPGYNG 1116
Query: 582 NGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANK 641
+ + DVDEC P C++ G +C+ R+ S P G N+
Sbjct: 1117 DNCE-DDVDECASQP-----------CQH---GGSCIDLVARYLCSCPPGTLGVLCEINE 1161
Query: 642 QVCKPRNPCTDGTHDCNKNAKC-NYLGHYSDPMYRCECKPGYAG 684
C P P G C N C + +G +RC C PGY G
Sbjct: 1162 DDCGPGPPLDSGPR-CLHNGTCVDLVGG-----FRCTCPPGYTG 1199
Score = 57.4 bits (137), Expect = 8e-08
Identities = 102/391 (26%), Positives = 141/391 (36%), Gaps = 93/391 (23%)
Query: 333 VDSCTECHCQNSVTICKKVSCPIMPCSNATVPDGECCPRCWPSDSADDGWSPWSEWTSCS 392
+D C C + T +V+ C P G+ C D+ +P E C
Sbjct: 315 IDDCATAVCFHGATCHDRVASFYCAC-----PMGKTGLLCHLDDACVS--NPCHEDAICD 367
Query: 393 TSCGNGIQQ-------RGRSCDSLNNRCEGSSVQTRTC-HIQECDKRFKQDGGWSHWSPW 444
T+ NG G +CD + C S+ C H+ C +
Sbjct: 368 TNPVNGRAICTCPPGFTGGACDQDVDEC---SIGANPCEHLGRCV------------NTQ 412
Query: 445 SSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGW-GPWSPWDI 503
S CG G T R C + + PC +A + C G+ G + DI
Sbjct: 413 GSFLCQCGRGY-TGPR-CETDVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDI 470
Query: 504 ----CSVTCGGGVQK---RSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPC 556
S GGV K C P+ F G C DV E C S PC
Sbjct: 471 DECQSSPCVNGGVCKDRVNGFSCTCPSG-FSGSTCQLDVDE-------------CASTPC 516
Query: 557 FAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYN 616
G KC PDG ++C C G+ G + +VD+C PD C H+G RC + ++
Sbjct: 517 RNGAKCVDQPDG-YEC-RCAEGFEGT-LCDRNVDDCS--PDPC--HHG--RCVDGIASFS 567
Query: 617 CLPCPPRFTG-----------SQPFGQGVEHA-TANKQVCKPRNPCTDGT---------H 655
C C P +TG SQP G + +K +C+ C GT
Sbjct: 568 C-ACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCR----CPSGTTGVNCEVNID 622
Query: 656 DCNKNAKCNYLGHYSDPM--YRCECKPGYAG 684
DC N C + G D + Y C C+PG+ G
Sbjct: 623 DCASN-PCTF-GVCRDGINRYDCVCQPGFTG 651
Score = 54.7 bits (130), Expect = 5e-07
Identities = 74/271 (27%), Positives = 103/271 (38%), Gaps = 75/271 (27%)
Query: 450 TCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCG 509
TC DGV T C P P+ G+ C + E + + +AC NGG C T G
Sbjct: 250 TCVDGVNTYN--CQCP-PEWTGQFCTEDVDECQL-QPNACH-NGG--------TCFNTLG 296
Query: 510 GGVQKRSRLCNNPTPQFGGKDCVGDVTE--------NQICNKQ------DCPI------- 548
G S +C N + G+ C ++ + C+ + CP+
Sbjct: 297 G----HSCVCVNG---WTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLC 349
Query: 549 ---DGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGE 605
D C+SNPC C + P CPPG++G G DVDEC + C H G
Sbjct: 350 HLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPC-EHLG- 406
Query: 606 HRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPR-NPCTDGTHDCNKNAKC- 663
RC NT + C C +TG + C+ N C G C A C
Sbjct: 407 -RCVNTQGSFLC-QCGRGYTGPR---------------CETDVNECLSG--PCRNQATCL 447
Query: 664 NYLGHYSDPMYRCECKPGYAGNGIICGEDTD 694
+ +G ++ C C G+ G C D D
Sbjct: 448 DRIGQFT-----CICMAGFTGT--YCEVDID 471
Score = 38.5 bits (88), Expect = 0.038
Identities = 60/266 (22%), Positives = 86/266 (32%), Gaps = 90/266 (33%)
Query: 451 CGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDACPINGGWGPWSPWDICSVTCGG 510
C DG+ + C +P G CE + E C+ C G C
Sbjct: 559 CVDGIASFSCAC---APGYTGTRCESQVDE---CRSQPCRHGG-------------KCLD 599
Query: 511 GVQKRSRLCNNPTPQFGGK------DCVGDVTENQIC----NKQDC-------------P 547
V K LC P+ G DC + +C N+ DC
Sbjct: 600 LVDKY--LCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVE 657
Query: 548 IDGCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACF--NHNGE 605
I+ C S+PC G C +G ++C CPPG +P C +H
Sbjct: 658 INECASSPCGEGGSCVDGENG-FRC-LCPPG---------------SLPPLCLPPSHPCA 700
Query: 606 HR------CENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNK 659
H C + G+ C+ C P ++G + Q + Q C+ C+
Sbjct: 701 HEPCSHGICYDAPGGFRCV-CEPGWSGPR-CSQSLARDACESQPCRAGGTCS-------- 750
Query: 660 NAKCNYLGHYSDPM-YRCECKPGYAG 684
SD M + C C PG G
Sbjct: 751 ----------SDGMGFHCTCPPGVQG 766
Score = 33.1 bits (74), Expect = 1.6
Identities = 38/144 (26%), Positives = 48/144 (33%), Gaps = 24/144 (16%)
Query: 551 CLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQC-------TDVDECKEVPDACFNHN 603
C C GV C P G +C ACPPG SG + C P C H
Sbjct: 1293 CRELQCPVGVPCQQTPRGP-RC-ACPPGLSGPSCRSFPGSPPGASNASCAAAP--CL-HG 1347
Query: 604 GEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKC 663
G R P + C C +TG + + + C PR C D + +C
Sbjct: 1348 GSCRPAPLAPFFRC-ACAQGWTGPRCEAPAAAPEVSEEPRC-PRAACQAKRGDQRCDREC 1405
Query: 664 NYLG----------HYSDPMYRCE 677
N G DP +CE
Sbjct: 1406 NSPGCGWDGGDCSLSVGDPWRQCE 1429
>gi|153792351 ADAM metallopeptidase with thrombospondin type 1
motif, 8 preproprotein [Homo sapiens]
Length = 889
Score = 83.2 bits (204), Expect = 1e-15
Identities = 40/105 (38%), Positives = 52/105 (49%), Gaps = 7/105 (6%)
Query: 453 DGVITRIRLCNSPSPQMNGKPC-------EGEARETKACKKDACPINGGWGPWSPWDICS 505
DG N P +G PC EG + ++ +GGW PW PW CS
Sbjct: 480 DGAEPLCHTKNGSLPWADGTPCGPGHLCSEGSCLPEEEVERPKPVADGGWAPWGPWGECS 539
Query: 506 VTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
TCGGGVQ R C +P PQ GG+ C+G + Q C+ ++CP DG
Sbjct: 540 RTCGGGVQFSHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDG 584
Score = 70.5 bits (171), Expect = 9e-12
Identities = 48/156 (30%), Positives = 65/156 (41%), Gaps = 33/156 (21%)
Query: 348 CKKVSCP-IMPCSNATVPDGECCPRCW-------PSDSADDGWSPWSEWTSCSTSCGNGI 399
C+++ P C N + D C + W P +G PW++ T C
Sbjct: 452 CRQIFGPDFRHCPNTSAQD--VCAQLWCHTDGAEPLCHTKNGSLPWADGTPCGP------ 503
Query: 400 QQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQ--DGGWSHWSPWSSCSVTCGDGVIT 457
G C EGS C +E +R K DGGW+ W PW CS TCG GV
Sbjct: 504 ---GHLCS------EGS------CLPEEEVERPKPVADGGWAPWGPWGECSRTCGGGVQF 548
Query: 458 RIRLCNSPSPQMNGKPCEGEARETKACKKDACPING 493
R C P PQ G+ C G + ++C + CP +G
Sbjct: 549 SHRECKDPEPQNGGRYCLGRRAKYQSCHTEECPPDG 584
Score = 35.0 bits (79), Expect = 0.42
Identities = 17/49 (34%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 444 WSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEG-EARETKACKKDACPI 491
WS CS TCG G R C PS Q + + + + K C+ CP+
Sbjct: 841 WSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL 889
Score = 32.3 bits (72), Expect = 2.7
Identities = 17/49 (34%), Positives = 24/49 (48%), Gaps = 1/49 (2%)
Query: 501 WDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTEN-QICNKQDCPI 548
W CS TCG G Q+R+ C +P+ Q E+ + C Q CP+
Sbjct: 841 WSECSSTCGAGWQRRTVECRDPSGQASATCNKALKPEDAKPCESQLCPL 889
>gi|33624896 ADAM metallopeptidase with thrombospondin type 1 motif, 9
preproprotein [Homo sapiens]
Length = 1935
Score = 82.0 bits (201), Expect = 3e-15
Identities = 78/275 (28%), Positives = 103/275 (37%), Gaps = 48/275 (17%)
Query: 331 WTVDSCTECHCQNSV------TICKKVSCPIMPCSNATVPDGECCPRCWPSDSAD----- 379
W V S +EC Q + C K S + V DG C PS+
Sbjct: 939 WHVASRSECSAQCGLGYRTLDIYCAKYSR--LDGKTEKVDDGFCSSHPKPSNREKCSGEC 996
Query: 380 --DGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRT--CHIQECDKRFKQD 435
GW +S WT CS SC G Q+R C + N S T IQ C +
Sbjct: 997 NTGGWR-YSAWTECSKSCDGGTQRRRAICVNTRNDVLDDSKCTHQEKVTIQRCS-----E 1050
Query: 436 GGWSHWSP--WSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARET--KACKKDACPI 491
W WS C VTCG G R C ++N + C+ E + T + C++ C
Sbjct: 1051 FPCPQWKSGDWSECLVTCGKGHKHRQVWCQFGEDRLNDRMCDPETKPTSMQTCQQPEC-- 1108
Query: 492 NGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICN-------KQ 544
W PW CSVTCG G Q R+ C T V ++ CN Q
Sbjct: 1109 -ASWQA-GPWGQCSVTCGQGYQLRAVKCIIGTYM--------SVVDDNDCNAATRPTDTQ 1158
Query: 545 DCPIDGCLSNPCFAGVKCTSY--PDGSWKCGACPP 577
DC + C P + ++Y P W+ G+ P
Sbjct: 1159 DCELPSCHPPPAAPETRRSTYSAPRTQWRFGSWTP 1193
Score = 73.9 bits (180), Expect = 8e-13
Identities = 67/254 (26%), Positives = 98/254 (38%), Gaps = 52/254 (20%)
Query: 353 CPIMPCSNATVPDG---------ECCPR-CWPSDSADDGWSPW--SEWTSCSTSCGNGIQ 400
C + PC T G + PR PS + G + W W +CS++C G Q
Sbjct: 1290 CSMSPCPQRTPDSGLAQHPFQNEDYRPRSASPSRTHVLGGNQWRTGPWGACSSTCAGGSQ 1349
Query: 401 QRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGGWSHWS--PWSSCSVTCGDGVITR 458
+R C N V+ I+ ++R + G W+ W C+ CG G+ TR
Sbjct: 1350 RRVVVCQDENGYTANDCVE----RIKPDEQRACESGPCPQWAYGNWGECTKLCGGGIRTR 1405
Query: 459 IRLC-NSPSPQMNGKPCE--GEARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKR 515
+ +C S + CE + + + C ACP + W PW CSV+CG G ++R
Sbjct: 1406 LVVCQRSNGERFPDLSCEILDKPPDREQCNTHACPHDAAWST-GPWSSCSVSCGRGHKQR 1464
Query: 516 SRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAGVKCTSYPDGSWKC--G 573
+ C KD G E+ C K + P G KC G
Sbjct: 1465 NVYCM-------AKD--GSHLESDYC-------------------KHLAKPHGHRKCRGG 1496
Query: 574 ACPPGYSGNGIQCT 587
CP +G QC+
Sbjct: 1497 RCPKWKAGAWSQCS 1510
Score = 72.0 bits (175), Expect = 3e-12
Identities = 68/248 (27%), Positives = 88/248 (35%), Gaps = 69/248 (27%)
Query: 358 CSNATVP-DGECC--PRCWPSDSADDG-----------WSPWSEWTSCSTSCGNGIQQRG 403
C+ AT P D + C P C P +A + W + WT CS +CG G + R
Sbjct: 1148 CNAATRPTDTQDCELPSCHPPPAAPETRRSTYSAPRTQWR-FGSWTPCSATCGKGTRMRY 1206
Query: 404 RSCDSLNNRCEGSS--------VQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGV 455
SC N S V C + C G W WSSCSVTCG G
Sbjct: 1207 VSCRDENGSVADESACATLPRPVAKEECSVTPC-------GQWKALD-WSSCSVTCGQGR 1258
Query: 456 ITRIRLC--------------------------NSPSPQ------MNGKPCEGEARETKA 483
TR +C SP PQ + P + E ++
Sbjct: 1259 ATRQVMCVNYSDHVIDRSECDQDYIPETDQDCSMSPCPQRTPDSGLAQHPFQNEDYRPRS 1318
Query: 484 CKKDACPINGGWGPW--SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDV--TENQ 539
+ GG W PW CS TC GG Q+R +C + + DCV + E +
Sbjct: 1319 ASPSRTHVLGG-NQWRTGPWGACSSTCAGGSQRRVVVCQDEN-GYTANDCVERIKPDEQR 1376
Query: 540 ICNKQDCP 547
C CP
Sbjct: 1377 ACESGPCP 1384
Score = 69.7 bits (169), Expect = 2e-11
Identities = 36/89 (40%), Positives = 47/89 (52%), Gaps = 12/89 (13%)
Query: 466 SPQMNGKPCEGEARETKACKKDAC-------PI-NGGWGPWSPWDICSVTCGGGVQKRSR 517
+P +G CE K CK C P+ +G WG WSP+ CS TCGGG++ R
Sbjct: 558 TPWADGTECE----PGKHCKYGFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIR 613
Query: 518 LCNNPTPQFGGKDCVGDVTENQICNKQDC 546
CN P P+ GGK CVG + + CN + C
Sbjct: 614 ECNRPEPKNGGKYCVGRRMKFKSCNTEPC 642
Score = 67.4 bits (163), Expect = 8e-11
Identities = 73/265 (27%), Positives = 107/265 (40%), Gaps = 44/265 (16%)
Query: 364 PDGECC-PRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRT 422
PD E C P D+A WS W+SCS SCG G +QR C + +GS +++
Sbjct: 1429 PDREQCNTHACPHDAA---WST-GPWSSCSVSCGRGHKQRNVYCMAK----DGSHLESDY 1480
Query: 423 C-HIQECDKRFKQDGG----WSHWSPWSSCSVTCGDGVITRIRLCNSPSPQM-NGKPCEG 476
C H+ + K GG W WS CSV+CG GV R C + ++ C
Sbjct: 1481 CKHLAKPHGHRKCRGGRCPKWKA-GAWSQCSVSCGRGVQQRHVGCQIGTHKIARETECNP 1539
Query: 477 EAR--ETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLC--NNPTPQFGGKDCV 532
R + C+ CP+ W W C+ TCG G + R +C +N G +
Sbjct: 1540 YTRPESERDCQGPRCPLY-TWRA-EEWQECTKTCGEGSRYRKVVCVDDNKNEVHGAR--- 1594
Query: 533 GDVTENQICNKQDCPID--GCLSNPCFAGVKCTSYPDGSW-KCG-ACPPGYSGNGIQCTD 588
C+ P+D C PC + G W +C C GY + C++
Sbjct: 1595 --------CDVSKRPVDRESCSLQPCE-----YVWITGEWSECSVTCGKGYKQRLVSCSE 1641
Query: 589 VDECKEVPDACFNHNGEHRCENTDP 613
+ KE + +++ C T P
Sbjct: 1642 IYTGKENYE--YSYQTTINCPGTQP 1664
Score = 66.2 bits (160), Expect = 2e-10
Identities = 26/55 (47%), Positives = 33/55 (60%)
Query: 435 DGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKKDAC 489
DG W WSP+ +CS TCG G+ T IR CN P P+ GK C G + K+C + C
Sbjct: 588 DGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKFKSCNTEPC 642
Score = 61.2 bits (147), Expect = 5e-09
Identities = 62/251 (24%), Positives = 96/251 (38%), Gaps = 44/251 (17%)
Query: 388 WTSCSTSCGNGIQQRGRSCDSLNNRCEGS---SVQTRTCHIQECDKRFKQDGGWSHWSPW 444
W+ CS SCG G+QQR C ++ + TR ++C W W
Sbjct: 1506 WSQCSVSCGRGVQQRHVGCQIGTHKIARETECNPYTRPESERDCQGPRCPLYTW-RAEEW 1564
Query: 445 SSCSVTCGDGVITRIRLC-NSPSPQMNGKPCEGEAR--ETKACKKDACPINGGWGPWSPW 501
C+ TCG+G R +C + +++G C+ R + ++C C G WS
Sbjct: 1565 QECTKTCGEGSRYRKVVCVDDNKNEVHGARCDVSKRPVDRESCSLQPCEYVWITGEWSE- 1623
Query: 502 DICSVTCGGGVQKRSRLCNNPTPQFGGKD-----------CVGDVTEN-QICNKQDCPID 549
CSVTCG G ++R C+ + GK+ C G + C +DCP+
Sbjct: 1624 --CSVTCGKGYKQRLVSCSE---IYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDCPVS 1678
Query: 550 GCLSNPCFAGVKCTSYPDGSW-KCG-ACPPGYSGNGIQC-TDVDECKEVPDACFNHNGEH 606
++ G+W C +C G +QC T+ D+ +
Sbjct: 1679 -------------ATWRVGNWGSCSVSCGVGVMQRSVQCLTNEDQPSHLCHTDLKPEERK 1725
Query: 607 RCENTDPGYNC 617
C N YNC
Sbjct: 1726 TCRNV---YNC 1733
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/227 (25%), Positives = 83/227 (36%), Gaps = 50/227 (22%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTC-------HIQE-----CD 429
W+ W +CS C G ++R C +++ +V + C HI E CD
Sbjct: 881 WNSHGPWQACSKPC-QGERKRKLVCTRESDQL---TVSDQRCDRLPQPGHITEPCGTDCD 936
Query: 430 KRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKP-------CEGEARETK 482
R+ H + S CS CG G T C S +++GK C + +
Sbjct: 937 LRW-------HVASRSECSAQCGLGYRTLDIYCAKYS-RLDGKTEKVDDGFCSSHPKPSN 988
Query: 483 ACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICN 542
K GGW +S W CS +C GG Q+R +C N DV ++ C
Sbjct: 989 REKCSGECNTGGWR-YSAWTECSKSCDGGTQRRRAICVNTR---------NDVLDDSKCT 1038
Query: 543 KQD-CPIDGCLSNPCFAGVKCTSYPDGSWK--CGACPPGYSGNGIQC 586
Q+ I C P C + G W C G+ + C
Sbjct: 1039 HQEKVTIQRCSEFP------CPQWKSGDWSECLVTCGKGHKHRQVWC 1079
Score = 45.1 bits (105), Expect = 4e-04
Identities = 27/90 (30%), Positives = 38/90 (42%), Gaps = 19/90 (21%)
Query: 387 EWTSCSTSCGNGIQQRGRSCDSLNN-------------RCEGSS-VQTRTCHIQECDKRF 432
EW+ CS +CG G +QR SC + C G+ C++++C
Sbjct: 1620 EWSECSVTCGKGYKQRLVSCSEIYTGKENYEYSYQTTINCPGTQPPSVHPCYLRDC---- 1675
Query: 433 KQDGGWSHWSPWSSCSVTCGDGVITRIRLC 462
W W SCSV+CG GV+ R C
Sbjct: 1676 PVSATW-RVGNWGSCSVSCGVGVMQRSVQC 1704
Score = 43.5 bits (101), Expect = 0.001
Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 366 GECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNR-----CEGSSVQT 420
G C P+ D W WS + +CS +CG GI+ R C+ + C G ++
Sbjct: 575 GFCVPKEMDVPVTDGSWGSWSPFGTCSRTCGGGIKTAIRECNRPEPKNGGKYCVGRRMKF 634
Query: 421 RTCHIQECDKR 431
++C+ + C K+
Sbjct: 635 KSCNTEPCLKQ 645
>gi|38016904 thrombospondin repeat containing 1 isoform 1 [Homo
sapiens]
Length = 1074
Score = 81.3 bits (199), Expect = 5e-15
Identities = 86/299 (28%), Positives = 109/299 (36%), Gaps = 48/299 (16%)
Query: 366 GECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTC-H 424
G CP W + EWTSCS SCG G Q R C GSSV C H
Sbjct: 720 GTPCPPYWEA----------GEWTSCSRSCGPGTQHRQLQCRQ-EFGGGGSSVPPERCGH 768
Query: 425 I------QECDKRFKQDGGWSHWSPWSSCSVTCGDGVITR-IRLCNSPSPQMNGKPCEG- 476
+ Q C R G W SPWS CSV CG G +R +R + +++ + C
Sbjct: 769 LPRPNITQSCQLRL--CGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASG 826
Query: 477 --EARETKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGD 534
+ +AC C WS CS CG G+Q+RS +C G
Sbjct: 827 PPQPPSREACDMGPCTTAWFHSDWS--SKCSAECGTGIQRRSVVCLGSGAALGPGQGEAG 884
Query: 535 VTENQICNKQDCPID--GCLSNPCFAGVKCTSYPDGSWKCGACPPGYSGNGIQCTDVDEC 592
Q C P D C PC + + G W G C G+G Q D+ C
Sbjct: 885 AGTGQSCPTGSRPPDMRACSLGPC---ERTWRWYTGPW--GEC-SSECGSGTQRRDI-IC 937
Query: 593 KEVPDACFNHNGEHRCENTDPGYNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCT 651
FN C + LP PP Q GQ A ++ P +PC+
Sbjct: 938 VSKLGTEFNVTSPSNCSH-------LPRPPALQPCQ--GQ----ACQDRWFSTPWSPCS 983
Score = 57.4 bits (137), Expect = 8e-08
Identities = 57/199 (28%), Positives = 74/199 (37%), Gaps = 46/199 (23%)
Query: 386 SEWTS-CSTSCGNGIQQRGRSC---------------DSLNNRCEGSS--VQTRTCHIQE 427
S+W+S CS CG GIQ+R C C S R C +
Sbjct: 848 SDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGP 907
Query: 428 CDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLC--------NSPSPQMNGKPCEGEAR 479
C++ ++ W + PW CS CG G R +C N SP C R
Sbjct: 908 CERTWR----W-YTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSN----CSHLPR 958
Query: 480 ET--KACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDV-- 535
+ C+ AC PWSP CS +C GG Q R C + T Q C +
Sbjct: 959 PPALQPCQGQACQDRWFSTPWSP---CSRSCQGGTQTREVQCLS-TNQTLSTRCPPQLRP 1014
Query: 536 TENQICNKQDC---PIDGC 551
+ + CN Q C P D C
Sbjct: 1015 SRKRPCNSQPCSQRPDDQC 1033
Score = 54.3 bits (129), Expect = 7e-07
Identities = 64/232 (27%), Positives = 83/232 (35%), Gaps = 53/232 (22%)
Query: 383 SPWSEW-----TSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQECDKRFKQDGG 437
SP + W ++CS SCG G+ + C S R G + R+C R
Sbjct: 663 SPAAYWKRVGHSACSASCGKGVWRPIFLCIS---RESGEELDERSC---AAGARPPASPE 716
Query: 438 WSHWSP---------WSSCSVTCGDGVITRIRLC--------NSPSPQMNGKPCEGEARE 480
H +P W+SCS +CG G R C +S P+ G
Sbjct: 717 PCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGH--LPRPNI 774
Query: 481 TKACKKDACPINGGWGPWSPWDICSVTCGGGVQKRSRLC--NNPTPQFGGKDCVGDVTEN 538
T++C+ C G W SPW CSV CG G + R C NN GD
Sbjct: 775 TQSCQLRLC---GHWEVGSPWSQCSVRCGRGQRSRQVRCVGNN-----------GDEVSE 820
Query: 539 QICNK---QDCPIDGCLSNPCFAGVKCTSYPDGSWKCGA-CPPGYSGNGIQC 586
Q C Q + C PC + D S KC A C G + C
Sbjct: 821 QECASGPPQPPSREACDMGPC---TTAWFHSDWSSKCSAECGTGIQRRSVVC 869
Score = 48.9 bits (115), Expect = 3e-05
Identities = 20/33 (60%), Positives = 21/33 (63%)
Query: 493 GGWGPWSPWDICSVTCGGGVQKRSRLCNNPTPQ 525
G WGPW W CS CG GVQ+RSR C PT Q
Sbjct: 45 GVWGPWVQWASCSQPCGVGVQRRSRTCQLPTVQ 77
Score = 48.1 bits (113), Expect = 5e-05
Identities = 61/250 (24%), Positives = 90/250 (36%), Gaps = 59/250 (23%)
Query: 445 SSCSVTCGDGVITRIRLCNS--PSPQMNGKPCEGEAR---ETKACKKDACPINGGWGPWS 499
S+CS +CG GV I LC S +++ + C AR + C CP G W+
Sbjct: 674 SACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASPEPCHGTPCPPYWEAGEWT 733
Query: 500 PWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPIDGCLSNPCFAG 559
CS +CG G Q R C +FGG G + C G L P
Sbjct: 734 S---CSRSCGPGTQHRQLQCRQ---EFGGG---GSSVPPERC--------GHLPRPNIT- 775
Query: 560 VKCTSYPDGSWKCGACPPGYSGNGIQCTDVDECKEVPDACFNHNGEHRCENTDPGYNCLP 619
C G W+ G+ +S ++C ++V C +NG+ E C
Sbjct: 776 QSCQLRLCGHWEVGS---PWSQCSVRCGRGQRSRQV--RCVGNNGDEVSEQ-----ECAS 825
Query: 620 CPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMYRCECK 679
PP QP +++ C PCT + ++KC+ EC
Sbjct: 826 GPP-----QP---------PSREAC-DMGPCTTAWFHSDWSSKCS-----------AECG 859
Query: 680 PGYAGNGIIC 689
G ++C
Sbjct: 860 TGIQRRSVVC 869
Score = 43.9 bits (102), Expect = 0.001
Identities = 14/25 (56%), Positives = 18/25 (72%)
Query: 382 WSPWSEWTSCSTSCGNGIQQRGRSC 406
W PW +W SCS CG G+Q+R R+C
Sbjct: 47 WGPWVQWASCSQPCGVGVQRRSRTC 71
Score = 41.2 bits (95), Expect = 0.006
Identities = 21/56 (37%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 415 GSSVQTRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMN 470
G S+QT T ++ +G W W W+SCS CG GV R R C P+ Q++
Sbjct: 30 GHSLQTPT------EEGQGPEGVWGPWVQWASCSQPCGVGVQRRSRTCQLPTVQLH 79
>gi|223718260 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 80.5 bits (197), Expect = 9e-15
Identities = 78/276 (28%), Positives = 106/276 (38%), Gaps = 37/276 (13%)
Query: 330 EWTVDSCTEC--HCQNSVTICKKVSCPIMP--CSNATVPDGECCPRCWPSDSADDGWSPW 385
+W + +EC C + + + C C T P GE + D W+
Sbjct: 688 QWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE---KNCTGPPCDRQWTV- 743
Query: 386 SEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSS---VQTRTCHIQEC-DKRFKQDGGWSHW 441
S+W CS SCG G R C + + R S ++T+ I C DK +HW
Sbjct: 744 SDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCP-----AHW 798
Query: 442 --SPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKK---DACPINGGWG 496
W C+ TCG GV R+ LC + NGKP E KK ++
Sbjct: 799 LAQDWERCNTTCGRGVKKRLVLCMELA---NGKPQTRSGPECGLAKKPPEESTCFERPCF 855
Query: 497 PW--SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPI----DG 550
W SPW C+ TCG GV+ R C T G D + Q C+ Q CP D
Sbjct: 856 KWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDS 915
Query: 551 CLSNP---CFAGVK---CTSYPDGSWKCGACPPGYS 580
C P C +K C + C +C P +S
Sbjct: 916 CQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS 951
Score = 57.0 bits (136), Expect = 1e-07
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLC----NNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
WG W+ W CS +CGGGV + R C P G + C G Q+C Q+CP DG
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109
Score = 57.0 bits (136), Expect = 1e-07
Identities = 79/326 (24%), Positives = 107/326 (32%), Gaps = 97/326 (29%)
Query: 367 ECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ 426
EC PR W + S W+ CS +CG G Q R C + + SSV + C
Sbjct: 621 ECQPR-WETSS----------WSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAA 669
Query: 427 EC-----DKRFKQDGGWSHW--SPWSSCSVTCGD-GVITR-------IRLCNSPSPQMNG 471
E K + W S WS C+ CG+ V+TR +LC+ + +
Sbjct: 670 EAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729
Query: 472 KPCEGEARETKACKKDACPINGGWGP---------------------------------- 497
K C G + + D P +G G
Sbjct: 730 KNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPC 789
Query: 498 --------W--SPWDICSVTCGGGVQKRSRLC---NNPTPQF-GGKDC--VGDVTENQIC 541
W W+ C+ TCG GV+KR LC N PQ G +C E C
Sbjct: 790 GDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTC 849
Query: 542 NKQDC------PIDGCLSNPCFAGVKCTSYP--DGSWKCGACPPGYSGNGIQCTDVDECK 593
++ C P C + C GV+ G+ C P G Q D+ C
Sbjct: 850 FERPCFKWYTSPWSEC-TKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCP 908
Query: 594 EVP--DACFNHNGEHRCENTDPGYNC 617
P D+C PG NC
Sbjct: 909 TEPPDDSC----------QDQPGTNC 924
Score = 51.6 bits (122), Expect = 4e-06
Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 9/63 (14%)
Query: 375 SDSADDGWSPWSEWTSCSTSCGNGI--------QQRGRSCDSLNNR-CEGSSVQTRTCHI 425
+D+ W W++WT+CS SCG G+ QQR +S NR C G+S + + C +
Sbjct: 43 TDATAFWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRV 102
Query: 426 QEC 428
QEC
Sbjct: 103 QEC 105
Score = 45.8 bits (107), Expect = 2e-04
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 438 WSHWSPWSSCSVTCGDGVITRIRLC----NSPSPQMNGKPCEGEARETKACKKDACPING 493
W W+ W++CS +CG GV ++ R C P + C G ++ + C+ CP +G
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109
>gi|41281450 ADAMTS-like 2 precursor [Homo sapiens]
Length = 951
Score = 80.5 bits (197), Expect = 9e-15
Identities = 78/276 (28%), Positives = 106/276 (38%), Gaps = 37/276 (13%)
Query: 330 EWTVDSCTEC--HCQNSVTICKKVSCPIMP--CSNATVPDGECCPRCWPSDSADDGWSPW 385
+W + +EC C + + + C C T P GE + D W+
Sbjct: 688 QWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE---KNCTGPPCDRQWTV- 743
Query: 386 SEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSS---VQTRTCHIQEC-DKRFKQDGGWSHW 441
S+W CS SCG G R C + + R S ++T+ I C DK +HW
Sbjct: 744 SDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPCGDKNCP-----AHW 798
Query: 442 --SPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEARETKACKK---DACPINGGWG 496
W C+ TCG GV R+ LC + NGKP E KK ++
Sbjct: 799 LAQDWERCNTTCGRGVKKRLVLCMELA---NGKPQTRSGPECGLAKKPPEESTCFERPCF 855
Query: 497 PW--SPWDICSVTCGGGVQKRSRLCNNPTPQFGGKDCVGDVTENQICNKQDCPI----DG 550
W SPW C+ TCG GV+ R C T G D + Q C+ Q CP D
Sbjct: 856 KWYTSPWSECTKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCPTEPPDDS 915
Query: 551 CLSNP---CFAGVK---CTSYPDGSWKCGACPPGYS 580
C P C +K C + C +C P +S
Sbjct: 916 CQDQPGTNCALAIKVNLCGHWYYSKACCRSCRPPHS 951
Score = 57.0 bits (136), Expect = 1e-07
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 495 WGPWSPWDICSVTCGGGVQKRSRLC----NNPTPQFGGKDCVGDVTENQICNKQDCPIDG 550
WG W+ W CS +CGGGV + R C P G + C G Q+C Q+CP DG
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109
Score = 57.0 bits (136), Expect = 1e-07
Identities = 79/326 (24%), Positives = 107/326 (32%), Gaps = 97/326 (29%)
Query: 367 ECCPRCWPSDSADDGWSPWSEWTSCSTSCGNGIQQRGRSCDSLNNRCEGSSVQTRTCHIQ 426
EC PR W + S W+ CS +CG G Q R C + + SSV + C
Sbjct: 621 ECQPR-WETSS----------WSECSRTCGEGYQFRVVRCWKMLSPGFDSSVYSDLCEAA 669
Query: 427 EC-----DKRFKQDGGWSHW--SPWSSCSVTCGD-GVITR-------IRLCNSPSPQMNG 471
E K + W S WS C+ CG+ V+TR +LC+ + +
Sbjct: 670 EAVRPEERKTCRNPACGPQWEMSEWSECTAKCGERSVVTRDIRCSEDEKLCDPNTRPVGE 729
Query: 472 KPCEGEARETKACKKDACPINGGWGP---------------------------------- 497
K C G + + D P +G G
Sbjct: 730 KNCTGPPCDRQWTVSDWGPCSGSCGQGRTIRHVYCKTSDGRVVPESQCQMETKPLAIHPC 789
Query: 498 --------W--SPWDICSVTCGGGVQKRSRLC---NNPTPQF-GGKDC--VGDVTENQIC 541
W W+ C+ TCG GV+KR LC N PQ G +C E C
Sbjct: 790 GDKNCPAHWLAQDWERCNTTCGRGVKKRLVLCMELANGKPQTRSGPECGLAKKPPEESTC 849
Query: 542 NKQDC------PIDGCLSNPCFAGVKCTSYP--DGSWKCGACPPGYSGNGIQCTDVDECK 593
++ C P C + C GV+ G+ C P G Q D+ C
Sbjct: 850 FERPCFKWYTSPWSEC-TKTCGVGVRMRDVKCYQGTDIVRGCDPLVKPVGRQACDLQPCP 908
Query: 594 EVP--DACFNHNGEHRCENTDPGYNC 617
P D+C PG NC
Sbjct: 909 TEPPDDSC----------QDQPGTNC 924
Score = 51.6 bits (122), Expect = 4e-06
Identities = 24/63 (38%), Positives = 35/63 (55%), Gaps = 9/63 (14%)
Query: 375 SDSADDGWSPWSEWTSCSTSCGNGI--------QQRGRSCDSLNNR-CEGSSVQTRTCHI 425
+D+ W W++WT+CS SCG G+ QQR +S NR C G+S + + C +
Sbjct: 43 TDATAFWWGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRV 102
Query: 426 QEC 428
QEC
Sbjct: 103 QEC 105
Score = 45.8 bits (107), Expect = 2e-04
Identities = 18/60 (30%), Positives = 30/60 (50%), Gaps = 4/60 (6%)
Query: 438 WSHWSPWSSCSVTCGDGVITRIRLC----NSPSPQMNGKPCEGEARETKACKKDACPING 493
W W+ W++CS +CG GV ++ R C P + C G ++ + C+ CP +G
Sbjct: 50 WGEWTKWTACSRSCGGGVTSQERHCLQQRRKSVPGPGNRTCTGTSKRYQLCRVQECPPDG 109
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.137 0.451
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,409,608
Number of Sequences: 37866
Number of extensions: 2923780
Number of successful extensions: 11269
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 140
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 7315
Number of HSP's gapped (non-prelim): 2142
length of query: 1170
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1057
effective length of database: 13,968,660
effective search space: 14764873620
effective search space used: 14764873620
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.