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Search of human proteins with 40316926
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316926 clusterin-like 1 (retinal) [Homo sapiens]
(466 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316926 clusterin-like 1 (retinal) [Homo sapiens] 953 0.0
gi|7657490 clusterin-like 1 (retinal) [Homo sapiens] 953 0.0
gi|42740907 clusterin isoform 2 [Homo sapiens] 156 3e-38
gi|42716297 clusterin isoform 1 [Homo sapiens] 156 3e-38
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 40 0.003
gi|222537750 ankyrin repeat domain 30B [Homo sapiens] 40 0.005
gi|110611228 utrophin [Homo sapiens] 39 0.013
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 38 0.022
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 37 0.038
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa... 37 0.038
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s... 37 0.038
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 37 0.050
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 36 0.065
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 36 0.065
gi|32698688 citron [Homo sapiens] 36 0.065
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 36 0.085
gi|58530842 desmoplakin isoform II [Homo sapiens] 36 0.085
gi|58530840 desmoplakin isoform I [Homo sapiens] 36 0.085
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 36 0.085
gi|219689136 coiled-coil domain containing 68 [Homo sapiens] 35 0.11
gi|13376818 coiled-coil domain containing 68 [Homo sapiens] 35 0.11
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 35 0.11
gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens] 35 0.15
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 35 0.15
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 35 0.15
gi|55770834 centromere protein F [Homo sapiens] 35 0.19
gi|109255234 centrosomal protein 290kDa [Homo sapiens] 34 0.25
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 34 0.25
gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens] 34 0.25
gi|13236553 nucleolar protein 12 [Homo sapiens] 34 0.25
>gi|40316926 clusterin-like 1 (retinal) [Homo sapiens]
Length = 466
Score = 953 bits (2464), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK 60
MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK
Sbjct: 1 MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK 60
Query: 61 IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL 120
IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL
Sbjct: 61 IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL 120
Query: 121 ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM 180
ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM
Sbjct: 121 ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM 180
Query: 181 EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA 240
EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA
Sbjct: 181 EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA 240
Query: 241 DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ 300
DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ
Sbjct: 241 DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ 300
Query: 301 DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI 360
DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI
Sbjct: 301 DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI 360
Query: 361 LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM 420
LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM
Sbjct: 361 LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM 420
Query: 421 MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW 466
MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW
Sbjct: 421 MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW 466
>gi|7657490 clusterin-like 1 (retinal) [Homo sapiens]
Length = 466
Score = 953 bits (2464), Expect = 0.0
Identities = 466/466 (100%), Positives = 466/466 (100%)
Query: 1 MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK 60
MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK
Sbjct: 1 MKPPLLVFIVCLLWLKDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMK 60
Query: 61 IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL 120
IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL
Sbjct: 61 IMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCL 120
Query: 121 ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM 180
ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM
Sbjct: 121 ENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQM 180
Query: 181 EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA 240
EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA
Sbjct: 181 EDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAFSKEPMTKA 240
Query: 241 DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ 300
DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ
Sbjct: 241 DLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQ 300
Query: 301 DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI 360
DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI
Sbjct: 301 DRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQI 360
Query: 361 LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM 420
LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM
Sbjct: 361 LQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETM 420
Query: 421 MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW 466
MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW
Sbjct: 421 MTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKEHFKTW 466
>gi|42740907 clusterin isoform 2 [Homo sapiens]
Length = 449
Score = 156 bits (395), Expect = 3e-38
Identities = 122/478 (25%), Positives = 219/478 (45%), Gaps = 51/478 (10%)
Query: 1 MKPPLLVFIVCLLWLKDSHCAPTWK------DKTAISENLKSFSEVGEIDADEEVKKALT 54
M LL+F+ LL TW+ D+T L+ S G ++E++ A+
Sbjct: 1 MMKTLLLFVGLLL---------TWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVN 51
Query: 55 GIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWG 114
G+KQ+K ++E+ +E L+S L++ +++K++AL E + L+E +C E++ W
Sbjct: 52 GVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWE 111
Query: 115 ECRSCLENNCMRIYT-TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEE 173
EC+ CL+ CM+ Y C+ V ++E F + F F + D + L+E
Sbjct: 112 ECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDR------IDSLLEN 165
Query: 174 DAQLTQMEDV----FSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFIS-DTDLTEPYF 228
D Q T M DV FS+ + ++ LF F R+ Q + H++ P+F
Sbjct: 166 DRQQTHMLDVMQDHFSRASSIIDELFQDRF-FTREPQDTY------HYLPFSLPHRRPHF 218
Query: 229 FPAFSKEPMTKADLE-QCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAP 287
F F K + ++ + ++ NF +F F I+E+ + D+ A
Sbjct: 219 F--FPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEA---------QQAMDIHFHSPAF 267
Query: 288 DHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDC----PDVPALHTEL 343
H DR +C E+ N + C + ++C KC+ LS DC P L EL
Sbjct: 268 QHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRREL 327
Query: 344 DEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQ 403
DE++++ ++Y ++L+ + + +T+ L+E++ QF WVS LAN + + +
Sbjct: 328 DESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVT 387
Query: 404 VVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKE 461
V H + + + S T+ +P+E S ++ F+ V KALQ +++
Sbjct: 388 TVAS-HTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRK 444
>gi|42716297 clusterin isoform 1 [Homo sapiens]
Length = 501
Score = 156 bits (395), Expect = 3e-38
Identities = 122/478 (25%), Positives = 219/478 (45%), Gaps = 51/478 (10%)
Query: 1 MKPPLLVFIVCLLWLKDSHCAPTWK------DKTAISENLKSFSEVGEIDADEEVKKALT 54
M LL+F+ LL TW+ D+T L+ S G ++E++ A+
Sbjct: 53 MMKTLLLFVGLLL---------TWESGQVLGDQTVSDNELQEMSNQGSKYVNKEIQNAVN 103
Query: 55 GIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWG 114
G+KQ+K ++E+ +E L+S L++ +++K++AL E + L+E +C E++ W
Sbjct: 104 GVKQIKTLIEKTNEERKTLLSNLEEAKKKKEDALNETRESETKLKELPGVCNETMMALWE 163
Query: 115 ECRSCLENNCMRIYT-TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEE 173
EC+ CL+ CM+ Y C+ V ++E F + F F + D + L+E
Sbjct: 164 ECKPCLKQTCMKFYARVCRSGSGLVGRQLEEFLNQSSPFYFWMNGDR------IDSLLEN 217
Query: 174 DAQLTQMEDV----FSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFIS-DTDLTEPYF 228
D Q T M DV FS+ + ++ LF F R+ Q + H++ P+F
Sbjct: 218 DRQQTHMLDVMQDHFSRASSIIDELFQDRF-FTREPQDTY------HYLPFSLPHRRPHF 270
Query: 229 FPAFSKEPMTKADLE-QCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAP 287
F F K + ++ + ++ NF +F F I+E+ + D+ A
Sbjct: 271 F--FPKSRIVRSLMPFSPYEPLNFHAMFQPFLEMIHEA---------QQAMDIHFHSPAF 319
Query: 288 DHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDC----PDVPALHTEL 343
H DR +C E+ N + C + ++C KC+ LS DC P L EL
Sbjct: 320 QHPPTEFIREGDDDRTVCREIRHNSTGCLRMKDQCDKCREILSVDCSTNNPSQAKLRREL 379
Query: 344 DEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQ 403
DE++++ ++Y ++L+ + + +T+ L+E++ QF WVS LAN + + +
Sbjct: 380 DESLQVAERLTRKYNELLKSYQWKMLNTSSLLEQLNEQFNWVSRLANLTQGEDQYYLRVT 439
Query: 404 VVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQHFKE 461
V H + + + S T+ +P+E S ++ F+ V KALQ +++
Sbjct: 440 TVAS-HTSDSDVPSGVTEVVVKLFDSDPITVTVPVEVSRKNPKFMETVAEKALQEYRK 496
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 40.4 bits (93), Expect = 0.003
Identities = 90/465 (19%), Positives = 188/465 (40%), Gaps = 49/465 (10%)
Query: 30 ISENLKSFSEVGEIDADEEV-KKALTGIKQMKIMMERKEKEHTNLMSTLKKCRE----EK 84
ISE L+ S G A E+ KK ++M+ +E +H +TL+K + E
Sbjct: 1150 ISERLEEAS--GATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAEL 1207
Query: 85 QEALKLLNEVQEHLEEEERLCRESLADSWG--ECRSCLENNCMRIYTTCQPSWSSVKNKI 142
E + L V++ LE+E+ + + D E S ++N R T + +S +K K
Sbjct: 1208 GEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKD 1267
Query: 143 ERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVF 202
E+ + I H+ N + + + E ++ + E + SQLT +L + +
Sbjct: 1268 EQQTQLI-------HDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELK 1320
Query: 203 RQMQQEFD-QTFQSHFISDTDLTEPYFFPAFSKEPMTKADLEQCW-----DIPNFFQLFC 256
RQM++E + +H + + + +E KA+L++ ++ + +
Sbjct: 1321 RQMEEETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYE 1380
Query: 257 NFSVSIYESVSETITKMLKAIEDLPKQDKAPDHG----GLISKMLPGQDRGLCGELDQNL 312
++ E + E K+ + +++ + + + + L G+ L +L+++
Sbjct: 1381 TDAIQRTEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSH 1440
Query: 313 SRC--------------FKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYG 358
+ C ++ +K + QA L + +L TEL ++ N +
Sbjct: 1441 TACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTEL---FKMRNAYEEVVD 1497
Query: 359 QILQMTRKH---LEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISK 415
Q+ + R++ E+ + L E++ + E E + +QV EG++
Sbjct: 1498 QLETLRRENKNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEH 1557
Query: 416 QDETMM---TDLSILPSSNFTLKIPLEESAESSNFIGYVVAKALQ 457
++ ++ +LS + S I +E E A+ALQ
Sbjct: 1558 EESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQ 1602
Score = 30.0 bits (66), Expect = 4.7
Identities = 32/185 (17%), Positives = 82/185 (44%), Gaps = 18/185 (9%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
+A+E+ KKA+T MM + K+ + + L++ ++ ++ +K ++Q L+E E+
Sbjct: 1754 NAEEKAKKAITD----AAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQ 1806
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTC---QPSWSSVKNKIERFFRKIYQFLFPFHEDN 160
L + + LEN + Q + ++ RK+ + + ED+
Sbjct: 1807 LALKGGKKQIQK----LENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDH 1862
Query: 161 EKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISD 220
+ L + + + + A++ + + N+ +R R++Q E ++ + I++
Sbjct: 1863 KNILRLQDLVDKLQAKVKSYKRQAEEAEEQANTQLSRC----RRVQHELEEAAERADIAE 1918
Query: 221 TDLTE 225
+ + +
Sbjct: 1919 SQVNK 1923
>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
Length = 1392
Score = 40.0 bits (92), Expect = 0.005
Identities = 33/149 (22%), Positives = 65/149 (43%), Gaps = 9/149 (6%)
Query: 173 EDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDLTEPYFFPAF 232
E++Q T++E+ F+ T ++ +++ D T+Q + E FP+
Sbjct: 427 ENSQCTKVEEDFNLATKIISKSAAQNYTCLP------DATYQKDIKTINHKIEDQMFPSE 480
Query: 233 SKEPMTKADLEQCWDIPNFFQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGL 292
SK + D E WD + F+ V I ES+ + + ++ + +E+LP++ A
Sbjct: 481 SKR---EEDEEYSWDSGSLFESSAKTQVCIPESMYQKVMEINREVEELPEKPSAFKPAVE 537
Query: 293 ISKMLPGQDRGLCGELDQNLSRCFKFHEK 321
+ K +P + L E ++ F K
Sbjct: 538 MQKTVPNKAFELKNEQTLRAAQMFPSESK 566
>gi|110611228 utrophin [Homo sapiens]
Length = 3433
Score = 38.5 bits (88), Expect = 0.013
Identities = 86/373 (23%), Positives = 140/373 (37%), Gaps = 60/373 (16%)
Query: 16 KDSHCAPTWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMS 75
K++ W T KS SE D D E+ A +K ++ K K N ++
Sbjct: 1551 KEAASLSEWLSATETELVQKSTSEGLLGDLDTEISWAKNVLKDLE-----KRKADLNTIT 1605
Query: 76 TLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSW 135
E AL+ L E E + EE RLC L W R+ E+ C + Q
Sbjct: 1606 -------ESSAALQNLIEGSEPILEE-RLC--VLNAGWSRVRTWTEDWCNTLMNH-QNQL 1654
Query: 136 SSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIE------EDAQLTQMEDVFSQLTV 189
+ +YQ E +K E++++ +DA L Q+E+V Q +
Sbjct: 1655 EIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEEIVKRLVSELDDANL-QVENVRDQALI 1713
Query: 190 DVNSLFNRSFNVFRQMQQEFDQTFQ--SHFISDTDLTEPYFFPAFSKEPMTKADLEQCWD 247
+N+ + S + E ++ F+ S I L ++EP L QC
Sbjct: 1714 LMNARGSSSRELVEPKLAELNRNFEKVSQHIKSAKLL-------IAQEP-----LYQCLV 1761
Query: 248 IPNFFQLFCNFSVSIYESVSETITKMLKAIE----DLPKQDKAPDHGGLISKMLPGQDRG 303
F+ FS E + I MLK +E + +K + I ++L +
Sbjct: 1762 TTETFETGVPFSD--LEKLENDIENMLKFVEKHLESSDEDEKMDEESAQIEEVLQRGEEM 1819
Query: 304 LCGELDQNLSRCFKFHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQILQM 363
L ++ N K +K + L LHT ++ I+ + + ++ GQ+
Sbjct: 1820 LHQPMEDN---------KKEKIRLQLL-------LLHTRYNK-IKAIPIQQRKMGQLASG 1862
Query: 364 TRKHLEDTAYLVE 376
R L T YLVE
Sbjct: 1863 IRSSLLPTDYLVE 1875
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 37.7 bits (86), Expect = 0.022
Identities = 48/207 (23%), Positives = 92/207 (44%), Gaps = 24/207 (11%)
Query: 32 ENLKSFSEVGEI------DADEEVKKALTGIKQMKIMME--RKEKEHTNLMSTLKKCREE 83
+ L+ F E+GE +A+E++ + MK +E +KE EH NL K +EE
Sbjct: 1564 QKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLS---VKSKEE 1620
Query: 84 KQEAL--KLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNK 141
+ +AL +L +E L E +R + +A + S +E + + S + K
Sbjct: 1621 ELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTK 1680
Query: 142 IERFFRKIY--QFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVN-----SL 194
++ R+++ + E ++ + I + + A T+ E+ SQ V S+
Sbjct: 1681 LQEREREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISV 1740
Query: 195 FNRSF----NVFRQMQQEFDQTFQSHF 217
R+ + +++ QE ++T SHF
Sbjct: 1741 LQRNLTEKEKLLQRVGQEKEETVSSHF 1767
Score = 34.3 bits (77), Expect = 0.25
Identities = 40/202 (19%), Positives = 81/202 (40%), Gaps = 26/202 (12%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKALTGI---------------KQMKIMMERKEKE 69
K T E L+ E E A EE++KAL+ +Q+K + + E+E
Sbjct: 392 KQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEE 451
Query: 70 HTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYT 129
+L L + ++E + +K +E E + + ++L + LA E L+
Sbjct: 452 RISLQQELSRVKQEVVDVMKKSSE--EQIAKLQKLHEKELARKEQELTKKLQTREREF-- 507
Query: 130 TCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTV 189
Q K + + KI Q ++ ++ L + E +++ A LT+ E+ L
Sbjct: 508 --QEQMKVALEKSQSEYLKISQ-----EKEQQESLALEELELQKKAILTESENKLRDLQQ 560
Query: 190 DVNSLFNRSFNVFRQMQQEFDQ 211
+ + R + +++ +
Sbjct: 561 EAETYRTRILELESSLEKSLQE 582
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 37.0 bits (84), Expect = 0.038
Identities = 78/425 (18%), Positives = 168/425 (39%), Gaps = 44/425 (10%)
Query: 30 ISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCRE----EKQ 85
+SE L+ V + K+ +K ++ +E +H +++ L+K E
Sbjct: 1147 LSERLEEAGGVTSTQIELNKKREAEFLK-LRRDLEEATLQHEAMVAALRKKHADSVAELG 1205
Query: 86 EALKLLNEVQEHLEEEERLCRESLADSWGECRSCLEN--NCMRIYTTCQPSWSSVKNKIE 143
E + L V++ LE+E+ + + D S ++ N +I T + S + K E
Sbjct: 1206 EQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNE 1265
Query: 144 RFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFR 203
R + + + + + E QL + E + SQL+ + ++ + R
Sbjct: 1266 EIQRSLSEL-------TTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKR 1318
Query: 204 QMQQEFD-QTFQSHFISDTDLTEPYFFPAFSKEPMTKADLEQCW-----DIPNFFQLFCN 257
Q+++E + +H + + + +E KA+L++ ++ + +
Sbjct: 1319 QLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYET 1378
Query: 258 FSVSIYESVSETITKMLKAIEDLPKQDKAPDHG------------GLISKMLPGQDRG-- 303
++ E + E K+ + ++D +Q +A + G + ++ +R
Sbjct: 1379 DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS 1438
Query: 304 LCGELDQNLSRCFK----FHEKCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQ 359
L LD+ K + KC++ QA L + +L TEL +L N + Q
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTEL---FKLKNAYEEALDQ 1495
Query: 360 ILQMTR--KHLE-DTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQ 416
+ + R K+LE + A L E++ + EL + E+ IQ+ E + +
Sbjct: 1496 LETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHE 1555
Query: 417 DETMM 421
+ ++
Sbjct: 1556 EAKIL 1560
Score = 31.2 bits (69), Expect = 2.1
Identities = 29/182 (15%), Positives = 82/182 (45%), Gaps = 12/182 (6%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
+A+E+ KKA+T MM + K+ + + L++ ++ ++ +K ++Q L+E E+
Sbjct: 1751 NAEEKAKKAITD----AAMMAEELKKEQDTSAHLERMKKNLEQTVK---DLQHRLDEAEQ 1803
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKD 163
L + + + + + + + SVK + ++ R++ + + ED +
Sbjct: 1804 LALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKG-LRKYERRVKELTYQSEEDRKNV 1862
Query: 164 LPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDL 223
L + + + + ++ + + + + N FR+ Q E ++ + I+++ +
Sbjct: 1863 LRLQDLVDKLQVKVKS----YKRQAEEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
Query: 224 TE 225
+
Sbjct: 1919 NK 1920
>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
sapiens]
Length = 1843
Score = 37.0 bits (84), Expect = 0.038
Identities = 81/411 (19%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLC 105
+ E+ + ++ + + + KE L T++ RE + +K+L + EHL +
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570
Query: 106 RESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLP 165
R+ S +E ++ + + + SS +KIE R+I + L + E E+
Sbjct: 571 RQRSQISAEARVKDIEKENKILHESIKET-SSKLSKIEFEKRQIKKELEHYKEKGERAEE 629
Query: 166 ISEKL--IEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDL 223
+ +L +E++ +L Q + ++T + + + + ++ +T S +L
Sbjct: 630 LENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF----KNL 685
Query: 224 TEPYFFPAFSKEPMTKADLEQCWDIPNFFQLFC--------NFSVSIYESVSETITKMLK 275
T + + KE ++ D E N L C ES E + K L+
Sbjct: 686 T--FQLESLEKE-NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLE 742
Query: 276 AIEDLPKQDKAPDHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPD 335
++ K+ ++ L +G LD R K E K L + D
Sbjct: 743 LLKASFKK----------TERLEVSYQG----LDIENQRLQKTLENSNKKIQQLESELQD 788
Query: 336 VPALHTELDEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPE- 394
+ + L + + + +S+++ Q L+ K LE +EK + Q ++ Q E
Sbjct: 789 LEMENQTLQKNLEELKISSKRLEQ-LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Query: 395 --TEIIFNSIQVVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAE 443
T + N++++ GN+ K+++T+ ++ I S LK +E+ E
Sbjct: 848 KDTTLEENNVKI------GNLEKENKTLSKEIGIYKESCVRLKELEKENKE 892
Score = 32.3 bits (72), Expect = 0.94
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 20/137 (14%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
D ++E K IK+ + + E E + L+ +E+ + A +L NE+ HLE+E
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL-HHLEKENE 642
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKD 163
L ++ + + L+ C +I Q + +++ER RK+ + L D+ K+
Sbjct: 643 LLQKKITN--------LKITCEKIEALEQEN-----SELERENRKLKKTL-----DSFKN 684
Query: 164 LPIS-EKLIEEDAQLTQ 179
L E L +E++QL +
Sbjct: 685 LTFQLESLEKENSQLDE 701
Score = 30.8 bits (68), Expect = 2.7
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 47 EEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEA----------LKLLNEVQE 96
+E + T K +K ++ + E T L + K +E+ Q+ +LL++++
Sbjct: 1259 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1318
Query: 97 HLEEEERLCRESLADSWGECRSCLENN 123
+LEEE R + + + R+ LE N
Sbjct: 1319 NLEEENRHLLDQIQTLMLQNRTLLEQN 1345
>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
sapiens]
Length = 1870
Score = 37.0 bits (84), Expect = 0.038
Identities = 81/411 (19%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLC 105
+ E+ + ++ + + + KE L T++ RE + +K+L + EHL +
Sbjct: 511 ENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSL 570
Query: 106 RESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLP 165
R+ S +E ++ + + + SS +KIE R+I + L + E E+
Sbjct: 571 RQRSQISAEARVKDIEKENKILHESIKET-SSKLSKIEFEKRQIKKELEHYKEKGERAEE 629
Query: 166 ISEKL--IEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTDL 223
+ +L +E++ +L Q + ++T + + + + ++ +T S +L
Sbjct: 630 LENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSF----KNL 685
Query: 224 TEPYFFPAFSKEPMTKADLEQCWDIPNFFQLFC--------NFSVSIYESVSETITKMLK 275
T + + KE ++ D E N L C ES E + K L+
Sbjct: 686 T--FQLESLEKE-NSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLE 742
Query: 276 AIEDLPKQDKAPDHGGLISKMLPGQDRGLCGELDQNLSRCFKFHEKCQKCQAHLSEDCPD 335
++ K+ ++ L +G LD R K E K L + D
Sbjct: 743 LLKASFKK----------TERLEVSYQG----LDIENQRLQKTLENSNKKIQQLESELQD 788
Query: 336 VPALHTELDEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRGQFGWVSELANQAPE- 394
+ + L + + + +S+++ Q L+ K LE +EK + Q ++ Q E
Sbjct: 789 LEMENQTLQKNLEELKISSKRLEQ-LEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEI 847
Query: 395 --TEIIFNSIQVVPRIHEGNISKQDETMMTDLSILPSSNFTLKIPLEESAE 443
T + N++++ GN+ K+++T+ ++ I S LK +E+ E
Sbjct: 848 KDTTLEENNVKI------GNLEKENKTLSKEIGIYKESCVRLKELEKENKE 892
Score = 32.3 bits (72), Expect = 0.94
Identities = 35/137 (25%), Positives = 66/137 (48%), Gaps = 20/137 (14%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
D ++E K IK+ + + E E + L+ +E+ + A +L NE+ HLE+E
Sbjct: 584 DIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENEL-HHLEKENE 642
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKD 163
L ++ + + L+ C +I Q + +++ER RK+ + L D+ K+
Sbjct: 643 LLQKKITN--------LKITCEKIEALEQEN-----SELERENRKLKKTL-----DSFKN 684
Query: 164 LPIS-EKLIEEDAQLTQ 179
L E L +E++QL +
Sbjct: 685 LTFQLESLEKENSQLDE 701
Score = 30.8 bits (68), Expect = 2.7
Identities = 21/87 (24%), Positives = 41/87 (47%), Gaps = 10/87 (11%)
Query: 47 EEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEA----------LKLLNEVQE 96
+E + T K +K ++ + E T L + K +E+ Q+ +LL++++
Sbjct: 1258 KETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKG 1317
Query: 97 HLEEEERLCRESLADSWGECRSCLENN 123
+LEEE R + + + R+ LE N
Sbjct: 1318 NLEEENRHLLDQIQTLMLQNRTLLEQN 1344
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 36.6 bits (83), Expect = 0.050
Identities = 21/82 (25%), Positives = 46/82 (56%), Gaps = 2/82 (2%)
Query: 31 SENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKL 90
+E + F E+ ++ +++ + A +++ ++ E +EKE L++ L++ EKQE ++L
Sbjct: 721 AEKFQIFQELDQLQKEKDEQYAKLELEKKRL--EEQEKEQVMLVAHLEEQLREKQEMIQL 778
Query: 91 LNEVQEHLEEEERLCRESLADS 112
L + EEE+ E + +S
Sbjct: 779 LRRGEVQWVEEEKRDLEGIRES 800
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 36.2 bits (82), Expect = 0.065
Identities = 31/154 (20%), Positives = 70/154 (45%), Gaps = 17/154 (11%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
+ +EE+ + I++++ MM+ +E++ L++ E+ QE + + E +E ++ +E
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEK-------LREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKD 163
+E +W + ++ + W + K+ R K+++ E EK
Sbjct: 477 KIQEQEEKTWRQ---------EKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 164 LPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNR 197
EK+ E++ +L Q E+ + V + L R
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 33.5 bits (75), Expect = 0.42
Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKA--LTGIKQMKIMMERKEKEHTNLMSTLKKCRE 82
++K + E+ KS ++ D ++++A L +Q+++ +R KE ++ + L+ +
Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ-AQV 282
Query: 83 EKQEALKLLNEVQEHL---------EEEERLCRESLADSWGECRSCLENNCMRIYTTCQP 133
E+ E LLN+ QE E+EE++C + L E + + M +
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH---EQEE 339
Query: 134 SWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMED 182
++K+ R KI + E EK EK+ E+D ++ + E+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 36.2 bits (82), Expect = 0.065
Identities = 31/154 (20%), Positives = 70/154 (45%), Gaps = 17/154 (11%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEER 103
+ +EE+ + I++++ MM+ +E++ L++ E+ QE + + E +E ++ +E
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEK-------LREVEEKMQEEEEKMQEQEEKIQRQEE 476
Query: 104 LCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKD 163
+E +W + ++ + W + K+ R K+++ E EK
Sbjct: 477 KIQEQEEKTWRQ---------EKLLKQEEKIWEQ-EEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 164 LPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNR 197
EK+ E++ +L Q E+ + V + L R
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
Score = 33.5 bits (75), Expect = 0.42
Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKA--LTGIKQMKIMMERKEKEHTNLMSTLKKCRE 82
++K + E+ KS ++ D ++++A L +Q+++ +R KE ++ + L+ +
Sbjct: 224 QEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQ-AQV 282
Query: 83 EKQEALKLLNEVQEHL---------EEEERLCRESLADSWGECRSCLENNCMRIYTTCQP 133
E+ E LLN+ QE E+EE++C + L E + + M +
Sbjct: 283 EENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH---EQEE 339
Query: 134 SWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMED 182
++K+ R KI + E EK EK+ E+D ++ + E+
Sbjct: 340 KIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEE 388
>gi|32698688 citron [Homo sapiens]
Length = 2027
Score = 36.2 bits (82), Expect = 0.065
Identities = 40/153 (26%), Positives = 68/153 (44%), Gaps = 18/153 (11%)
Query: 52 ALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKL---LNEVQEHLEEEERLCRES 108
A T + K++++ KE L + KC + +QE +L ++EV+ L ++E + S
Sbjct: 442 AKTSSMEKKLLIKSKE-----LQDSQDKCHKMEQEMTRLHRRVSEVEAVLSQKEVELKAS 496
Query: 109 LADSWGECRSCLENNCMRIYTTC---QPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLP 165
RS LE + T C + S + ++ + K Q L E + K
Sbjct: 497 ETQ-----RSLLEQDLATYITECSSLKRSLEQARMEVSQEDDKALQLLHDIREQSRKLQE 551
Query: 166 ISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRS 198
I E+ E AQ+ +M + +QL D+ S RS
Sbjct: 552 IKEQ--EYQAQVEEMRLMMNQLEEDLVSARRRS 582
Score = 31.6 bits (70), Expect = 1.6
Identities = 31/137 (22%), Positives = 60/137 (43%), Gaps = 16/137 (11%)
Query: 71 TNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTT 130
T L + E+K E + L E+Q L+E RES + R+ LE+ + T
Sbjct: 856 TRLREVSLEHEEQKLELKRQLTELQLSLQE-----RESQLTALQAARAALESQLRQAKTE 910
Query: 131 CQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVD 190
+ + + + +I Q L ++ ++ + L +T +E+ +QLT D
Sbjct: 911 LEETTAEAEEEI--------QALTAHRDEIQRKF---DALRNSCTVITDLEEQLNQLTED 959
Query: 191 VNSLFNRSFNVFRQMQQ 207
L N++F + +Q+ +
Sbjct: 960 NAELNNQNFYLSKQLDE 976
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 35.8 bits (81), Expect = 0.085
Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 10/138 (7%)
Query: 29 AISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEAL 88
A+ E+L +E A + +K L K++K + E + L S L R+ +QE +
Sbjct: 785 AVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLL---RDYEQEKV 841
Query: 89 KLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYT-----TCQPSWSSVKNKIE 143
L E++E E+E L + L ++ LEN + I TC S S + N+ E
Sbjct: 842 LLRKELEEIQSEKEALQSDLLEMKNANEKTRLENQNLLIQVEEVSQTC--SKSEIHNEKE 899
Query: 144 RFFRKIYQFLFPFHEDNE 161
+ F K ++ L P E E
Sbjct: 900 KCFIKEHENLKPLLEQKE 917
>gi|58530842 desmoplakin isoform II [Homo sapiens]
Length = 2272
Score = 35.8 bits (81), Expect = 0.085
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 43 IDADEEVKKAL--------TGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEV 94
++A+ VK+ L + Q K RKE+ + S +K EK + +
Sbjct: 1244 LEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERL 1303
Query: 95 QEHLEEEERLCRESLADSWGECRSCLENNCMR 126
Q ++ E CR L DS E +S LE R
Sbjct: 1304 QAEIKRIEERCRRKLEDSTRETQSQLETERSR 1335
Score = 30.0 bits (66), Expect = 4.7
Identities = 32/119 (26%), Positives = 52/119 (43%), Gaps = 11/119 (9%)
Query: 86 EALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQ------PSWSSVK 139
E LKL N E LEEE RL R++ +++ + L+ N + C S +K
Sbjct: 1025 EDLKLKNTKIEVLEEELRLARDANSENCNK-NKFLDQNLQKYQAECSQFKAKLASLEELK 1083
Query: 140 NKIERFFRKIYQFLFPFH----EDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSL 194
+ E + Q L + E NEK ++ ++ +E + +ED F Q D + L
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQL 1142
>gi|58530840 desmoplakin isoform I [Homo sapiens]
Length = 2871
Score = 35.8 bits (81), Expect = 0.085
Identities = 25/92 (27%), Positives = 38/92 (41%), Gaps = 8/92 (8%)
Query: 43 IDADEEVKKAL--------TGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEV 94
++A+ VK+ L + Q K RKE+ + S +K EK + +
Sbjct: 1843 LEAETRVKQRLECEKQQIQNDLNQWKTQYSRKEEAIRKIESEREKSEREKNSLRSEIERL 1902
Query: 95 QEHLEEEERLCRESLADSWGECRSCLENNCMR 126
Q ++ E CR L DS E +S LE R
Sbjct: 1903 QAEIKRIEERCRRKLEDSTRETQSQLETERSR 1934
Score = 31.6 bits (70), Expect = 1.6
Identities = 75/376 (19%), Positives = 150/376 (39%), Gaps = 35/376 (9%)
Query: 86 EALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQ------PSWSSVK 139
E LKL N E LEEE RL R++ +++ + L+ N + C S +K
Sbjct: 1025 EDLKLKNTKIEVLEEELRLARDANSENCNK-NKFLDQNLQKYQAECSQFKAKLASLEELK 1083
Query: 140 NKIERFFRKIYQFLFPFH----EDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLF 195
+ E + Q L + E NEK ++ ++ +E + +ED F Q D + L
Sbjct: 1084 RQAELDGKSAKQNLDKCYGQIKELNEKITRLTYEIEDEKRRRKSVEDRFDQQKNDYDQL- 1142
Query: 196 NRSFNVFRQMQQE---FDQTFQSHFISDTDLTEPYFFPAFSKEPMTKADLE-QCWDIPNF 251
RQ ++E + + I + + +E K + E + + N
Sbjct: 1143 ----QKARQCEKENLGWQKLESEKAIKEKEYEIERLRVLLQEEGTRKREYENELAKVRNH 1198
Query: 252 FQLFCNFSVSIYESVSETITKMLKAIEDLPKQDKAPDHGGLISKMLPGQDRGLCGELDQN 311
+ + + YE+ +K I + K+D + + + + L ++R L E+ +
Sbjct: 1199 YNEEMSNLRNKYETEINITKTTIKEI-SMQKEDDSKNLRNQLDR-LSRENRDLKDEIVRL 1256
Query: 312 LSRCFKFHEKCQKCQAHL-------SEDCPDVPALHTELDEAIRLVNVSNQQYGQILQMT 364
+ E+ ++ + + SE L EL + ++ + N ++ Q L+
Sbjct: 1257 NDSILQATEQRRRAEENALQQKACGSEIMQKKQHLEIELKQVMQQRSEDNARHKQSLEEA 1316
Query: 365 RKHLEDTAYLVEKMRGQFGWVSELANQAPETEIIFNSIQVVPRIHEGNISKQDETMMTDL 424
K ++D +E+++ +F E A + E E N + V ++ I T++
Sbjct: 1317 AKTIQDKNKEIERLKAEF---QEEAKRRWEYE---NELSKVRNNYDEEIISLKNQFETEI 1370
Query: 425 SILPSSNFTLKIPLEE 440
+I ++ L + EE
Sbjct: 1371 NITKTTIHQLTMQKEE 1386
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 35.8 bits (81), Expect = 0.085
Identities = 20/53 (37%), Positives = 31/53 (58%), Gaps = 7/53 (13%)
Query: 56 IKQMKIMMERKEKEHTNLMSTLKK----C---REEKQEALKLLNEVQEHLEEE 101
+KQ K E+ KEH L L+K C +EK+E ++ LN+++E LE+E
Sbjct: 445 VKQWKEQAEKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKE 497
>gi|219689136 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 35.4 bits (80), Expect = 0.11
Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)
Query: 47 EEVKKALTGIKQM----KIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEE 102
EEV+K KQ+ K+ E+K K+H ++ + + EEK + L + + +E+E+
Sbjct: 143 EEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEK 202
Query: 103 RLCRESLADSWGECRSCLENNCMRIYT--TCQPSWSSVKNKIERFFRKIYQFLFPFHEDN 160
R E + LEN +++ + T S ++ +I +I F H +
Sbjct: 203 RTLLER--------KLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQH 254
Query: 161 EKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSL--FNRSFNVFRQMQQEFDQTFQSHFI 218
+ + +++ L + + L VN L N+ + E +T S +
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAV 314
Query: 219 SDTDL 223
S ++L
Sbjct: 315 STSEL 319
Score = 31.6 bits (70), Expect = 1.6
Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 31/210 (14%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEH--TNLMSTLKKCRE 82
+DK + L + I+ E VKK T +++++ M + E H TN K C
Sbjct: 13 RDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGN 72
Query: 83 EKQE----------ALKLLNEVQE-------HLEEEERLCRESLADSWGECRSCLENNCM 125
+Q +L LL + + + +E + + L S + L N
Sbjct: 73 LQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQ 132
Query: 126 RIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDL--------PISEKLIEEDAQL 177
R++ Q V+ K E Q L + E+ L ++EKL E+ +Q+
Sbjct: 133 RLFENYQTQSEEVRKKQE----DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQI 188
Query: 178 TQMEDVFSQLTVDVNSLFNRSFNVFRQMQQ 207
T++E++ ++ + +L R ++ ++ Q
Sbjct: 189 TELENLVQRMEKEKRTLLERKLSLENKLLQ 218
>gi|13376818 coiled-coil domain containing 68 [Homo sapiens]
Length = 335
Score = 35.4 bits (80), Expect = 0.11
Identities = 39/185 (21%), Positives = 77/185 (41%), Gaps = 16/185 (8%)
Query: 47 EEVKKALTGIKQM----KIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEE 102
EEV+K KQ+ K+ E+K K+H ++ + + EEK + L + + +E+E+
Sbjct: 143 EEVRKKQEDSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQITELENLVQRMEKEK 202
Query: 103 RLCRESLADSWGECRSCLENNCMRIYT--TCQPSWSSVKNKIERFFRKIYQFLFPFHEDN 160
R E + LEN +++ + T S ++ +I +I F H +
Sbjct: 203 RTLLER--------KLSLENKLLQLKSSATYGKSCQDLQREISILQEQISHLQFVIHSQH 254
Query: 161 EKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSL--FNRSFNVFRQMQQEFDQTFQSHFI 218
+ + +++ L + + L VN L N+ + E +T S +
Sbjct: 255 QNLRSVIQEMEGLKNNLKEQDKRIENLREKVNILEAQNKELKTQVALSSETPRTKVSKAV 314
Query: 219 SDTDL 223
S ++L
Sbjct: 315 STSEL 319
Score = 31.6 bits (70), Expect = 1.6
Identities = 44/210 (20%), Positives = 85/210 (40%), Gaps = 31/210 (14%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEH--TNLMSTLKKCRE 82
+DK + L + I+ E VKK T +++++ M + E H TN K C
Sbjct: 13 RDKMEDNSALYESTSAHIIEETEYVKKIRTTLQKIRTQMFKDEIRHDSTNHKLDAKHCGN 72
Query: 83 EKQE----------ALKLLNEVQE-------HLEEEERLCRESLADSWGECRSCLENNCM 125
+Q +L LL + + + +E + + L S + L N
Sbjct: 73 LQQGSDSEMDPSCCSLDLLMKKIKGKDLQLLEMNKENEVLKIKLQASREAGAAALRNVAQ 132
Query: 126 RIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDL--------PISEKLIEEDAQL 177
R++ Q V+ K E Q L + E+ L ++EKL E+ +Q+
Sbjct: 133 RLFENYQTQSEEVRKKQE----DSKQLLQVNKLEKEQKLKQHVENLNQVAEKLEEKHSQI 188
Query: 178 TQMEDVFSQLTVDVNSLFNRSFNVFRQMQQ 207
T++E++ ++ + +L R ++ ++ Q
Sbjct: 189 TELENLVQRMEKEKRTLLERKLSLENKLLQ 218
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 35.4 bits (80), Expect = 0.11
Identities = 36/158 (22%), Positives = 77/158 (48%), Gaps = 12/158 (7%)
Query: 47 EEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCR 106
E+++K ++ +++++ + + E T L L+K + ++ L L V+ ++E E C
Sbjct: 426 EKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELE--CS 483
Query: 107 ESLADSWGECRSCLENNCMRIYTTCQPSWSSVKN---KIERFFRKIYQFLFPFHEDNEKD 163
ES + + L+++ ++ + KN KI++ RK+ F + K
Sbjct: 484 ESRLE---KAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKV 540
Query: 164 LPISEKLIEEDAQL----TQMEDVFSQLTVDVNSLFNR 197
+ ++EKLIEE +L ++ME+ LT + + L +
Sbjct: 541 MDVTEKLIEESKKLLKLKSEMEEKVYNLTRERDELIGK 578
Score = 29.3 bits (64), Expect = 8.0
Identities = 23/58 (39%), Positives = 31/58 (53%), Gaps = 10/58 (17%)
Query: 47 EEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREE----KQEALKLLNEVQEHLEE 100
E +KK L +Q K RKEKE+ L K R+E K AL L++E Q H+E+
Sbjct: 209 ERLKKLL---EQEKAYQARKEKENA---KRLNKLRDELVKLKSFALMLVDERQMHIEQ 260
>gi|4885399 structural maintenance of chromosomes 3 [Homo sapiens]
Length = 1217
Score = 35.0 bits (79), Expect = 0.15
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 44/210 (20%)
Query: 23 TWKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMER---KEKEH--------- 70
T + AI++ +K E D D + K GIK+++ MER EKEH
Sbjct: 862 TTSELEAINKRVKDTMARSE-DLDNSIDKTEAGIKELQKSMERWKNMEKEHMDAINHDTK 920
Query: 71 -----TNLMSTLKKCREEKQEALKLLNEV-QEHLEEEERLCRESLADSWGECRSCLENNC 124
TN L K +EE + ++ L + QE E+ + L + L +C + L+
Sbjct: 921 ELEKMTNRQGMLLKKKEECMKKIRELGSLPQEAFEKYQTLSLKQLFRKLEQCNTELK--- 977
Query: 125 MRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVF 184
+S V K + QF+ F E EK + E+L + ++ +V
Sbjct: 978 ---------KYSHVNKK------ALDQFV-NFSEQKEKLIKRQEELDRGYKSIMELMNVL 1021
Query: 185 SQLTVDVNSLFNRSFNVFRQMQQEFDQTFQ 214
+ L F+Q+ + F + FQ
Sbjct: 1022 ELRKYEAIQL------TFKQVSKNFSEVFQ 1045
Score = 32.7 bits (73), Expect = 0.72
Identities = 31/105 (29%), Positives = 45/105 (42%), Gaps = 13/105 (12%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLC 105
D + K L + ++ ERKE E +LM + RE+ E LK + E LEEE
Sbjct: 152 DSQRLKLLREVAGTRVYDERKE-ESISLMKETEGKREKINELLKYIEERLHTLEEE---- 206
Query: 106 RESLA--DSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRK 148
+E LA W + R LE YT + + K++ K
Sbjct: 207 KEELAQYQKWDKMRRALE------YTIYNQELNETRAKLDELSAK 245
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 35.0 bits (79), Expect = 0.15
Identities = 31/168 (18%), Positives = 71/168 (42%), Gaps = 14/168 (8%)
Query: 35 KSFSEVGEIDA--DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLN 92
K ++G+ D DE+ ++ + K+ + R ++E ++ +K +E + + L+
Sbjct: 23 KVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLH 82
Query: 93 EVQE---HLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKI 149
EV E + E+ ++ E W + L + + T + +KN+I + RK+
Sbjct: 83 EVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKL 142
Query: 150 YQF------LFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDV 191
+ L KD ++ + + + + + VF + VD+
Sbjct: 143 VDYDSARHHLEALQSSKRKD---ESRISKAEEEFQKAQKVFEEFNVDL 187
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 35.0 bits (79), Expect = 0.15
Identities = 31/168 (18%), Positives = 71/168 (42%), Gaps = 14/168 (8%)
Query: 35 KSFSEVGEIDA--DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLN 92
K ++G+ D DE+ ++ + K+ + R ++E ++ +K +E + + L+
Sbjct: 23 KVLQKLGKADETKDEQFEEYVQNFKRQEAEGTRLQRELRGYLAAIKGMQEASMKLTESLH 82
Query: 93 EVQE---HLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKI 149
EV E + E+ ++ E W + L + + T + +KN+I + RK+
Sbjct: 83 EVYEPDWYGREDVKMVGEKCDVLWEDFHQKLVDGSLLTLDTYLGQFPDIKNRIAKRSRKL 142
Query: 150 YQF------LFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDV 191
+ L KD ++ + + + + + VF + VD+
Sbjct: 143 VDYDSARHHLEALQSSKRKD---ESRISKAEEEFQKAQKVFEEFNVDL 187
>gi|55770834 centromere protein F [Homo sapiens]
Length = 3114
Score = 34.7 bits (78), Expect = 0.19
Identities = 32/143 (22%), Positives = 70/143 (48%), Gaps = 24/143 (16%)
Query: 47 EEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCR 106
EEV + GI+++++ +E EK+ ++ LK+ RE + ++LK + E+LE E ++
Sbjct: 2112 EEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKE-RERENDSLK---DKVENLERELQMSE 2167
Query: 107 ES----LADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEK 162
E+ + D+ EN+ + T +K +IE R + F +
Sbjct: 2168 ENQELVILDA--------ENSKAEVET--------LKTQIEEMARSLKVFELDLVTLRSE 2211
Query: 163 DLPISEKLIEEDAQLTQMEDVFS 185
+++++ E+ QL++++ + S
Sbjct: 2212 KENLTKQIQEKQGQLSELDKLLS 2234
Score = 34.7 bits (78), Expect = 0.19
Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 5/92 (5%)
Query: 23 TWKDKTAISENLKSFSEVGEID----ADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLK 78
T+++K E S ++ EID + EE+ +L Q+ +++ + ++ ++ LK
Sbjct: 2727 TYREKLTSKEECLSSQKL-EIDLLKSSKEELNNSLKATTQILEELKKTKMDNLKYVNQLK 2785
Query: 79 KCREEKQEALKLLNEVQEHLEEEERLCRESLA 110
K E Q +KLL + + LEEE+ + ++ L+
Sbjct: 2786 KENERAQGKMKLLIKSCKQLEEEKEILQKELS 2817
Score = 32.3 bits (72), Expect = 0.94
Identities = 31/181 (17%), Positives = 70/181 (38%), Gaps = 11/181 (6%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLC 105
++E+K + +++++ +E+ + E L KCR+E ++ E+
Sbjct: 305 EKEMKGQVNKFQELQLQLEKAKVELIEKEKVLNKCRDELVRTTAQYDQASTKYTALEQKL 364
Query: 106 RESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFHEDNEKDLP 165
++ D SC N + + +K K + F ++ + F +++ +
Sbjct: 365 KKLTED-----LSCQRQNAESARCSLE---QKIKEKEKEFQEELSRQQRSFQTLDQECIQ 416
Query: 166 ISEKLIEEDAQLTQMEDVFS---QLTVDVNSLFNRSFNVFRQMQQEFDQTFQSHFISDTD 222
+ +L +E Q M +V V + F+Q +Q FQ+ I + +
Sbjct: 417 MKARLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENE 476
Query: 223 L 223
L
Sbjct: 477 L 477
Score = 29.6 bits (65), Expect = 6.1
Identities = 32/188 (17%), Positives = 78/188 (41%), Gaps = 15/188 (7%)
Query: 24 WKDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREE 83
WK++ NL ++ +++++ + ++ +E + + NL + L+ + +
Sbjct: 2551 WKEQNLELRNLT-------VELEQKIQVLQSKNASLQDTLEVLQSSYKNLENELELTKMD 2603
Query: 84 KQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIE 143
K ++ +N++ E +R E +A E + L R+ Q +K+ +
Sbjct: 2604 KMSFVEKVNKMTAKETELQREMHE-MAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKD 2662
Query: 144 RFFR------KIYQFLFPFHEDN-EKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFN 196
+ ++ + L H+D EK+ + E++ E +L + E L +D N +
Sbjct: 2663 QLKELTLENSELKKSLDCMHKDQVEKEGKVREEIAEYQLRLHEAEKKHQALLLDTNKQYE 2722
Query: 197 RSFNVFRQ 204
+R+
Sbjct: 2723 VEIQTYRE 2730
>gi|109255234 centrosomal protein 290kDa [Homo sapiens]
Length = 2479
Score = 34.3 bits (77), Expect = 0.25
Identities = 89/429 (20%), Positives = 174/429 (40%), Gaps = 43/429 (10%)
Query: 25 KDKTAISENLKSFSEVGEIDADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEK 84
K+KT +E +E + D+E+ +AL +K + + E + + +K C+ +
Sbjct: 417 KEKTKEAERTAELAEADAREKDKELVEALKRLKDYESGVYGLE----DAVVEIKNCKNQ- 471
Query: 85 QEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENNCMRIYTTCQ-PSWSSVKNKIE 143
+K+ + E L +E ++D E + E + T + + K+ +
Sbjct: 472 ---IKIRDREIEILTKEINKLELKISDFLDENEALRERVGLEPKTMIDLTEFRNSKHLKQ 528
Query: 144 RFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFNRSFNVFR 203
+ +R Q L E E++ +K I + AQ S LT + +L R
Sbjct: 529 QQYRAENQILLKEIESLEEERLDLKKKIRQMAQERGKRSATSGLTTEDLNLTENISQGDR 588
Query: 204 QMQQEFDQTFQSHFISDTDLTEPYFFPAF-SKEPMTK-ADLEQCWDIPNFFQLFCNFSVS 261
+++ D +S +++E F S+E + K DLE+ + FQ V
Sbjct: 589 ISERKLD------LLSLKNMSEAQSKNEFLSRELIEKERDLERSRTVIAKFQNKLKELVE 642
Query: 262 IYESVSETITKMLKAIEDLPKQDKAPD-HGGLISKMLPGQDRGLCGELDQNLSRCFKFHE 320
+ + E + ++L+AI+++ K PD GG S ++P +R + +N F
Sbjct: 643 ENKQLEEGMKEILQAIKEMQKD---PDVKGGETSLIIPSLERLVNAIESKNAEGIF---- 695
Query: 321 KCQKCQAHLSEDCPDVPALHTELDEAIRLVNVSNQQYGQILQMTRKHLEDTAYLVEKMRG 380
HL + + EL + +R Y Q Q+ + +L+ ++ +
Sbjct: 696 ---DASLHLKAQVDQLTGRNEELRQELRESRKEAINYSQ--QLAKANLK-----IDHLEK 745
Query: 381 QFGWVSELANQAPETEIIFNSIQVVPRIHEGN---ISKQDETMMTDLSILPSSNFTLKIP 437
+ + L Q+ + ++F I + I + I+ Q+E ++ L L + LK
Sbjct: 746 E----TSLLRQSEGSNVVFKGIDLPDGIAPSSASIINSQNEYLIHLLQELENKEKKLK-N 800
Query: 438 LEESAESSN 446
LE+S E N
Sbjct: 801 LEDSLEDYN 809
Score = 32.7 bits (73), Expect = 0.72
Identities = 36/180 (20%), Positives = 84/180 (46%), Gaps = 25/180 (13%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEA-----LKLLNEVQEHL-- 98
++EVKK ++ +K ++++ +KE L S L+ +E A L+ ++ L
Sbjct: 1677 EDEVKKVKAEVEDLKYLLDQSQKESQCLKSELQAQKEANSRAPTTTMRNLVERLKSQLAL 1736
Query: 99 -EEEERLCRESLADSWGECRSCLENNCMRIYTTCQPSWSSVKNKIERFFRKIYQFLFPFH 157
E++++ +L + E + E + T+ + + +V+ ++R R++
Sbjct: 1737 KEKQQKALSRALLELRAEMTAAAEERIISA-TSQKEAHLNVQQIVDRHTREL-------- 1787
Query: 158 EDNEKDLPISEKLIEEDAQLTQMEDVFSQLTVDVNSLFN------RSFNVFRQMQQEFDQ 211
+ +DL +E L++ L ++ + LT ++N L N +++N + ++E DQ
Sbjct: 1788 KTQVEDL--NENLLKLKEALKTSKNRENSLTDNLNDLNNELQKKQKAYNKILREKEEIDQ 1845
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 34.3 bits (77), Expect = 0.25
Identities = 25/120 (20%), Positives = 55/120 (45%), Gaps = 6/120 (5%)
Query: 64 ERKEKEHTNLMSTLKKCREEKQEALKLLNEVQEHLEEEERLCRESLADSWGECRSCLENN 123
E K +E + KK REE++ ++ E +E ++E+E RE W E ++
Sbjct: 553 EEKMREEERMREREKKMREEEE----MMREQEEKMQEQEEKMREQEEKMW-EQEEKMQEQ 607
Query: 124 CMRIYTTCQPSW-SSVKNKIERFFRKIYQFLFPFHEDNEKDLPISEKLIEEDAQLTQMED 182
+++ + W ++K++ +++ E EK EK+ E++ ++ + E+
Sbjct: 608 EEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEE 667
>gi|42476130 ubiquitin interaction motif containing 1 [Homo sapiens]
Length = 719
Score = 34.3 bits (77), Expect = 0.25
Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 8/80 (10%)
Query: 44 DADEEVKKALTGIKQMKIMMERKEKEHTNLMSTLKKCREEKQEALKL------LNEVQEH 97
D+D E K G+++ K + K + + EE+Q AL L EV
Sbjct: 45 DSDGEEPKEENGLQKTKTKQSNRAK--CLAKRKIAQMTEEEQFALALKMSEQEAREVNSQ 102
Query: 98 LEEEERLCRESLADSWGECR 117
EEEE L R+++A+S CR
Sbjct: 103 EEEEEELLRKAIAESLNSCR 122
>gi|13236553 nucleolar protein 12 [Homo sapiens]
Length = 213
Score = 34.3 bits (77), Expect = 0.25
Identities = 26/66 (39%), Positives = 38/66 (57%), Gaps = 7/66 (10%)
Query: 46 DEEVKKALTGIKQMKIMMERKEKEHTNLMSTLK----KCREEK-QEALKLLNEVQEHLEE 100
+E+ ++ LTG + K+ ERK+ + LK K REE+ QE LK+L E +E LEE
Sbjct: 24 EEKRREYLTGFHKRKV--ERKKAAIEEIKQRLKEEQRKLREERHQEYLKMLAEREEALEE 81
Query: 101 EERLCR 106
+ L R
Sbjct: 82 ADELDR 87
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,774,560
Number of Sequences: 37866
Number of extensions: 807286
Number of successful extensions: 4858
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 4180
Number of HSP's gapped (non-prelim): 865
length of query: 466
length of database: 18,247,518
effective HSP length: 106
effective length of query: 360
effective length of database: 14,233,722
effective search space: 5124139920
effective search space used: 5124139920
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.