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Search of human proteins with 40316839
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
(1132 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 2268 0.0
gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 2206 0.0
gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 1463 0.0
gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 1463 0.0
gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 1207 0.0
gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 662 0.0
gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 656 0.0
gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 634 0.0
gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 632 0.0
gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 622 e-178
gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 595 e-169
gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 517 e-146
gi|65301139 ATPase, class II, type 9A [Homo sapiens] 445 e-124
gi|41327760 ATPase, class II, type 9B [Homo sapiens] 412 e-115
gi|149944474 ATPase, class V, type 10B [Homo sapiens] 361 2e-99
gi|222352161 ATPase, class V, type 10D [Homo sapiens] 348 2e-95
gi|14424433 ATPase, class V, type 10A [Homo sapiens] 345 1e-94
gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 173 7e-43
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 85 3e-16
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 85 3e-16
gi|66932949 ATPase type 13A4 [Homo sapiens] 83 1e-15
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 80 1e-14
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 79 2e-14
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 79 2e-14
gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 78 5e-14
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 75 5e-13
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 75 5e-13
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 67 7e-11
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 67 1e-10
gi|148839292 ATPase type 13A3 [Homo sapiens] 64 1e-09
>gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens]
Length = 1132
Score = 2268 bits (5877), Expect = 0.0
Identities = 1132/1132 (100%), Positives = 1132/1132 (100%)
Query: 1 MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP
Sbjct: 1 MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
Query: 61 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD
Sbjct: 61 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
Query: 121 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS
Sbjct: 121 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
Query: 181 LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR
Sbjct: 181 LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
Query: 241 SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF
Sbjct: 241 SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
Query: 301 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV
Sbjct: 301 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
Query: 361 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN
Sbjct: 361 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
Query: 421 SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN
Sbjct: 421 SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
Query: 481 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT
Sbjct: 481 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
Query: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC
Sbjct: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
Query: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA
Sbjct: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
Query: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE
Sbjct: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
Query: 721 LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ
Sbjct: 721 LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
Query: 781 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE
Sbjct: 781 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
Query: 841 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF
Sbjct: 841 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
Query: 901 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL
Sbjct: 901 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
Query: 961 YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF
Sbjct: 961 YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
Query: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS
Sbjct: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
Query: 1081 LFPEILLIVLKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNVL 1132
LFPEILLIVLKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNVL
Sbjct: 1081 LFPEILLIVLKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDESNVL 1132
>gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens]
Length = 1119
Score = 2206 bits (5716), Expect = 0.0
Identities = 1099/1099 (100%), Positives = 1099/1099 (100%)
Query: 1 MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP
Sbjct: 1 MQMVPSLPPASECAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLP 60
Query: 61 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD
Sbjct: 61 KNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRAD 120
Query: 121 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS
Sbjct: 121 NEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTAS 180
Query: 181 LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR
Sbjct: 181 LDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVAR 240
Query: 241 SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF
Sbjct: 241 SLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLF 300
Query: 301 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV
Sbjct: 301 ILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPV 360
Query: 361 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN
Sbjct: 361 SMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTEN 420
Query: 421 SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN
Sbjct: 421 SMEFIECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTN 480
Query: 481 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT
Sbjct: 481 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
Query: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC
Sbjct: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
Query: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA
Sbjct: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
Query: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE
Sbjct: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
Query: 721 LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ
Sbjct: 721 LLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQ 780
Query: 781 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE
Sbjct: 781 ICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKE 840
Query: 841 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF
Sbjct: 841 GRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGF 900
Query: 901 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL
Sbjct: 901 SQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFL 960
Query: 961 YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF
Sbjct: 961 YWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRF 1020
Query: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS
Sbjct: 1021 WTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
Query: 1081 LFPEILLIVLKNVRRRSAR 1099
LFPEILLIVLKNVRRRSAR
Sbjct: 1081 LFPEILLIVLKNVRRRSAR 1099
>gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens]
Length = 1134
Score = 1463 bits (3788), Expect = 0.0
Identities = 726/1130 (64%), Positives = 882/1130 (78%), Gaps = 23/1130 (2%)
Query: 13 CAGEEKRVGTRTVFVGNH-PVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIA 71
CAGEE V +RT++VG+ P EAYI QR+ DNRIVSSKYT WNF+PKNLFEQFRR+A
Sbjct: 14 CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73
Query: 72 NFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
NFYFLIIFLVQ+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH+ADN +N+ V+ I
Sbjct: 74 NFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFI 133
Query: 132 ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
++ K VRK+S K++VGD+V V+ DETFPCDLI LSS DGTC+VTTASLDGES+ KTHY
Sbjct: 134 QHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHY 193
Query: 192 AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
AV+DT T E I L A IECEQPQPDLYKFVGRIN+YS+ + V R LG ENLLL+G
Sbjct: 194 AVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRG 253
Query: 252 ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
ATLKNTEKI+GVA+YTGMETKMALNYQ KSQKRSAVEKS+NAFLIVYL IL++KA + T
Sbjct: 254 ATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTV 313
Query: 312 LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
LKY+WQS P+ DEPWYNQKT+ ER+ LK FTDFL+FMVLFN+IIPVSMYVTVEMQKF
Sbjct: 314 LKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKF 373
Query: 372 LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDG 431
LGS+FI+WD+D +DEE EG LVNTSDLNEELGQV+Y+FTDKTGTLTEN+MEF ECCI+G
Sbjct: 374 LGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEG 433
Query: 432 HKY-------KGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVD 484
H Y V E G+ D + + + REELF RALCLCHTV++K +D+VD
Sbjct: 434 HVYVPHVICNGQVLPESSGIDMIDSSPSV---NGREREELFFRALCLCHTVQVKDDDSVD 490
Query: 485 GATESAE----LTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
G +S + YISSSPDE+ALV+G +R GFT+L ++ YM + N+ IE +ELL
Sbjct: 491 GPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEI 550
Query: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
L+FD+VRRRMSVIVK+ G+I LFCKGADS++FPRV +++ + VERNA++G RTLC
Sbjct: 551 LSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLC 610
Query: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
VA+K + ++YE I + L AK+ALQDRE+K+ + ++ IE ++ L+GATAVED+LQ++AA
Sbjct: 611 VAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAA 670
Query: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
+TIEAL AG+KVWVLTGDKMETA +TCYAC+LF+ NT+LLELTTK IEE LH+
Sbjct: 671 DTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQS-----LHD 725
Query: 721 LLIEYRKKLLHEFPKSTR-SFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFL 779
+L E K +L TR + + Q+YGLIIDG+ LSLI+ +D SS NY+ +FL
Sbjct: 726 VLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785
Query: 780 QICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGK 839
+IC C+AVLCCRMAPLQKAQIV+++K K PITL+IGDGANDVSMILE+HVGIG+ GK
Sbjct: 786 EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845
Query: 840 EGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCG 899
EGRQAARNSDY++PKFKHLKK+LL HGH YY+RI+ LVQYFFYKN+CFI PQFLYQFFCG
Sbjct: 846 EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905
Query: 900 FSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPF 959
FSQQ LYD AYLT+YNI FTSLPIL YSL+EQH+ ID L DP LY ++ NA+L+ F
Sbjct: 906 FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965
Query: 960 LYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
+YWT L F+ VFFFG YF+F+ ++ NG+++GNWTFGT+VFTV+VFTVTLKLALDT
Sbjct: 966 IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025
Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFI 1079
+WTWINHFVIWGSL FYV FS WGG+IWPFL QRMY+VF QMLSS WLAI+LL+ I
Sbjct: 1026 YWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTI 1085
Query: 1080 SLFPEILLIVLKNVRRRSARRNLSCRRASDSLSARPSVRPLLLRTFSDES 1129
SL P++L VL +A + + S LS S +L +T S S
Sbjct: 1086 SLLPDVLKKVLCRQLWPTATERVQTK--SQCLSVEQSTIFMLSQTSSSLS 1133
>gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens]
Length = 1191
Score = 1463 bits (3787), Expect = 0.0
Identities = 717/1091 (65%), Positives = 868/1091 (79%), Gaps = 21/1091 (1%)
Query: 13 CAGEEKRVGTRTVFVGNH-PVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIA 71
CAGEE V +RT++VG+ P EAYI QR+ DNRIVSSKYT WNF+PKNLFEQFRR+A
Sbjct: 14 CAGEENWVDSRTIYVGHREPPPGAEAYIPQRYPDNRIVSSKYTFWNFIPKNLFEQFRRVA 73
Query: 72 NFYFLIIFLVQVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
NFYFLIIFLVQ+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH+ADN +N+ V+ I
Sbjct: 74 NFYFLIIFLVQLIIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHKADNAMNQCPVHFI 133
Query: 132 ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
++ K VRK+S K++VGD+V V+ DETFPCDLI LSS DGTC+VTTASLDGES+ KTHY
Sbjct: 134 QHGKLVRKQSRKLRVGDIVMVKEDETFPCDLIFLSSNRGDGTCHVTTASLDGESSHKTHY 193
Query: 192 AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
AV+DT T E I L A IECEQPQPDLYKFVGRIN+YS+ + V R LG ENLLL+G
Sbjct: 194 AVQDTKGFHTEEDIGGLHATIECEQPQPDLYKFVGRINVYSDLNDPVVRPLGSENLLLRG 253
Query: 252 ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
ATLKNTEKI+GVA+YTGMETKMALNYQ KSQKRSAVEKS+NAFLIVYL IL++KA + T
Sbjct: 254 ATLKNTEKIFGVAIYTGMETKMALNYQSKSQKRSAVEKSMNAFLIVYLCILISKALINTV 313
Query: 312 LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
LKY+WQS P+ DEPWYNQKT+ ER+ LK FTDFL+FMVLFN+IIPVSMYVTVEMQKF
Sbjct: 314 LKYMWQSEPFRDEPWYNQKTESERQRNLFLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKF 373
Query: 372 LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDG 431
LGS+FI+WD+D +DEE EG LVNTSDLNEELGQV+Y+FTDKTGTLTEN+MEF ECCI+G
Sbjct: 374 LGSYFITWDEDMFDEETGEGPLVNTSDLNEELGQVEYIFTDKTGTLTENNMEFKECCIEG 433
Query: 432 HKY-------KGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVD 484
H Y V E G+ D + + + REELF RALCLCHTV++K +D+VD
Sbjct: 434 HVYVPHVICNGQVLPESSGIDMIDSSPSV---NGREREELFFRALCLCHTVQVKDDDSVD 490
Query: 485 GATESAE----LTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
G +S + YISSSPDE+ALV+G +R GFT+L ++ YM + N+ IE +ELL
Sbjct: 491 GPRKSPDGGKSCVYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIERFELLEI 550
Query: 541 LNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGYRTLC 600
L+FD+VRRRMSVIVK+ G+I LFCKGADS++FPRV +++ + VERNA++G RTLC
Sbjct: 551 LSFDSVRRRMSVIVKSATGEIYLFCKGADSSIFPRVIEGKVDQIRARVERNAVEGLRTLC 610
Query: 601 VAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAA 660
VA+K + ++YE I + L AK+ALQDRE+K+ + ++ IE ++ L+GATAVED+LQ++AA
Sbjct: 611 VAYKRLIQEEYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAA 670
Query: 661 ETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHE 720
+TIEAL AG+KVWVLTGDKMETA +TCYAC+LF+ NT+LLELTTK IEE LH+
Sbjct: 671 DTIEALQKAGIKVWVLTGDKMETAAATCYACKLFRRNTQLLELTTKRIEEQS-----LHD 725
Query: 721 LLIEYRKKLLHEFPKSTR-SFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFL 779
+L E K +L TR + + Q+YGLIIDG+ LSLI+ +D SS NY+ +FL
Sbjct: 726 VLFELSKTVLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIMKPREDGSSGNYRELFL 785
Query: 780 QICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGK 839
+IC C+AVLCCRMAPLQKAQIV+++K K PITL+IGDGANDVSMILE+HVGIG+ GK
Sbjct: 786 EICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGDGANDVSMILEAHVGIGVIGK 845
Query: 840 EGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCG 899
EGRQAARNSDY++PKFKHLKK+LL HGH YY+RI+ LVQYFFYKN+CFI PQFLYQFFCG
Sbjct: 846 EGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQYFFYKNVCFIFPQFLYQFFCG 905
Query: 900 FSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPF 959
FSQQ LYD AYLT+YNI FTSLPIL YSL+EQH+ ID L DP LY ++ NA+L+ F
Sbjct: 906 FSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLKRDPTLYRDVAKNALLRWRVF 965
Query: 960 LYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
+YWT L F+ VFFFG YF+F+ ++ NG+++GNWTFGT+VFTV+VFTVTLKLALDT
Sbjct: 966 IYWTLLGLFDALVFFFGAYFVFENTTVTSNGQIFGNWTFGTLVFTVMVFTVTLKLALDTH 1025
Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFI 1079
+WTWINHFVIWGSL FYV FS WGG+IWPFL QRMY+VF QMLSS WLAI+LL+ I
Sbjct: 1026 YWTWINHFVIWGSLLFYVVFSLLWGGVIWPFLNYQRMYYVFIQMLSSGPAWLAIVLLVTI 1085
Query: 1080 SLFPEILLIVL 1090
SL P++L VL
Sbjct: 1086 SLLPDVLKKVL 1096
>gi|62632750 ATPase, class VI, type 11B [Homo sapiens]
Length = 1177
Score = 1207 bits (3124), Expect = 0.0
Identities = 611/1105 (55%), Positives = 788/1105 (71%), Gaps = 74/1105 (6%)
Query: 22 TRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLV 81
TRT++V N + Y Q+F DNRI+SSKYT+WNF+PKNLFEQFRR+ANFYFLIIFLV
Sbjct: 19 TRTIYVANR-FPQNGLYTPQKFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLV 77
Query: 82 QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
Q+ +DTPTSPVTSGLPLFFVITVTAIKQGYEDWLRH +DNEVN + VY++ + V+ S
Sbjct: 78 QLMIDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRS 137
Query: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
+ I+VGD+V + DE FP DL+LLSS DG+C+VTTASLDGE+N KTH AV +T L T
Sbjct: 138 KNIRVGDIVRIAKDEIFPADLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPETALLQT 197
Query: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
++DTL A IEC+QP+ DLY+F+GR+ I + +E + R LGPE+LLL+GA LKNT++I+
Sbjct: 198 VANLDTLVAVIECQQPEADLYRFMGRM-IITQQMEEIVRPLGPESLLLRGARLKNTKEIF 256
Query: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
GVAVYTGMETKMALNY+ KSQKRSAVEKS+N FLI+YL IL+++A + T LKY WQ+
Sbjct: 257 GVAVYTGMETKMALNYKSKSQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEK 316
Query: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
DEPWYNQKT+ +R + K+L+ +DFL+F+VL+NFIIP+S+YVTVEMQKFLGSFFI WD
Sbjct: 317 WDEPWYNQKTEHQRNSSKILRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDL 376
Query: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
D Y EE ++ A VNTSDLNEELGQV+YVFTDKTGTLTEN M+F EC I+G KY QE+
Sbjct: 377 DLYHEESDQKAQVNTSDLNEELGQVEYVFTDKTGTLTENEMQFRECSINGMKY----QEI 432
Query: 442 DGL--------SQTDGTLTYFDKVDK------------------------NREELFLRAL 469
+G ++G L+Y + +LF +A+
Sbjct: 433 NGRLVPEGPTPDSSEGNLSYLSSLSHLNNLSHLTTSSSFRTSPENETELIKEHDLFFKAV 492
Query: 470 CLCHTVEI---KTNDAVDGATES----AELTYISSSPDEIALVKGAKRYGFTFLGNRNGY 522
LCHTV+I +T+ DG +S ++L Y +SSPDE ALV+ A R G F+GN
Sbjct: 493 SLCHTVQISNVQTDCTGDGPWQSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEET 552
Query: 523 MRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEIE 582
M V+ K +E Y+LLH L FD+ RRRMSVIV+ G+ LLF KGA+S++ P+ EIE
Sbjct: 553 MEVKTLGK-LERYKLLHILEFDSDRRRMSVIVQAPSGEKLLFAKGAESSILPKCIGGEIE 611
Query: 583 LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETN 642
T++HV+ A+ G RTLC+A+++ +YE I++++ EA+ ALQ REEK+ VF IE +
Sbjct: 612 KTRIHVDEFALKGLRTLCIAYRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKD 671
Query: 643 MNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLE 702
+ L+GATAVED+LQD+ ETIEAL AG+KVWVLTGDK ETA S +C F +LE
Sbjct: 672 LILLGATAVEDRLQDKVRETIEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNILE 731
Query: 703 LTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLI 762
L +++ + E L + +++ + ++GL++DG++LSL
Sbjct: 732 LI------NQKSDSECAEQLRQLARRITED-------------HVIQHGLVVDGTSLSLA 772
Query: 763 LNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAN 822
L ++ +F+++C C+AVLCCRMAPLQKA+++R++K PITL++GDGAN
Sbjct: 773 L--------REHEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824
Query: 823 DVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFY 882
DVSMI E+HVGIGI GKEGRQAARNSDY++ +FK L KLL HGH YY+RIA LVQYFFY
Sbjct: 825 DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884
Query: 883 KNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDP 942
KN+CFI PQFLYQF+C FSQQ LYD+ YLT+YNICFTSLPIL YSLLEQH++ L + P
Sbjct: 885 KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944
Query: 943 RLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLF-QTASLEENGKVYGNWTFGTI 1001
LY IS N +L + FLYWT L +FFFG+Y L + SL NG+++GNWTFGT+
Sbjct: 945 TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFFGSYLLIGKDTSLLGNGQMFGNWTFGTL 1004
Query: 1002 VFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFA 1061
VFTV+V TVT+K+AL+T FWTWINH V WGS+ FY FS F+GGI+WPFL Q MYFVF
Sbjct: 1005 VFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYFVFSLFYGGILWPFLGSQNMYFVFI 1064
Query: 1062 QMLSSVSTWLAIILLIFISLFPEIL 1086
Q+LSS S W AIIL++ LF +I+
Sbjct: 1065 QLLSSGSAWFAIILMVVTCLFLDII 1089
>gi|157649069 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform b [Homo sapiens]
Length = 1149
Score = 662 bits (1707), Expect = 0.0
Identities = 387/1080 (35%), Positives = 595/1080 (55%), Gaps = 69/1080 (6%)
Query: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
Query: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
Query: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
EK+ VGD+V ++ E P D +LLSS CY+ T++LDGE+N K + T +
Sbjct: 149 EKVNVGDIVIIKGKEYIPADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
Query: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
Query: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
Query: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
Query: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y +Q
Sbjct: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGQNSQFG 438
Query: 442 DGLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAVDGATESAELTYIS 496
D + +D +L + + N FL + +CHT + E ++ Y +
Sbjct: 439 DEKTFSDSSL--LENLQNNHPTAPIICEFLTMMAVCHTAVPER--------EGDKIIYQA 488
Query: 497 SSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKT 556
+SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F + R+RMSVIV+T
Sbjct: 489 ASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEFTSARKRMSVIVRT 547
Query: 557 QEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC A EI+ D++
Sbjct: 548 PSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEW 607
Query: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ ETIE L A +K+W
Sbjct: 608 RAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIW 667
Query: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFP 734
+LTGDK ETA + ++C+L + N ++ + +++ + R L + +K
Sbjct: 668 ILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTTLGDALRK------ 721
Query: 735 KSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMA 794
++ LIIDG TL L + FL + + C AV+CCR++
Sbjct: 722 ------------ENDFALIIDGKTLKYALTFG-------VRQYFLDLALSCKAVICCRVS 762
Query: 795 PLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPK 854
PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG QAA +SDYS+ +
Sbjct: 763 PLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSIAQ 821
Query: 855 FKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMY 914
FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS Q L++ + +Y
Sbjct: 822 FKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIGLY 881
Query: 915 NICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTV 972
N+ FT++P L + E+ + + P LY K S NA L ++W F +
Sbjct: 882 NVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVFWVHCLNGLFHSVI 939
Query: 973 FFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGS 1032
F+ Q + NGK G V+T +V TV LK L+T +WTW +H IWGS
Sbjct: 940 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999
Query: 1033 LAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
+A +V F + +WP + M A + SS W+ ++ + SL +++ V+K
Sbjct: 1000 IALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVIK 1058
>gi|17978471 ATPase, aminophospholipid transporter (APLT), class I,
type 8A, member 1 isoform a [Homo sapiens]
Length = 1164
Score = 656 bits (1693), Expect = 0.0
Identities = 388/1093 (35%), Positives = 594/1093 (54%), Gaps = 80/1093 (7%)
Query: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
RT+F+ ++ +FC+N + ++KY + FLP+ L+ QFRR AN +FL I L+Q
Sbjct: 37 RTIFINQPQLT--------KFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQ 88
Query: 83 VTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKES 141
D +PT T+ +PL F++ V AIK+ ED RH+ADN VNK ++ N
Sbjct: 89 QIPDVSPTGRYTTLVPLLFILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHW 148
Query: 142 EKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCT 201
EK+ VG++V+V E P DLI LSS CY+ T++LDGE+N K + T +
Sbjct: 149 EKVAVGEIVKVTNGEHLPADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSDIKD 208
Query: 202 AESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIY 261
+S+ + IECE P LY FVG I + + LG + +LL+GA L+NT+ ++
Sbjct: 209 VDSLMRISGRIECESPNRHLYDFVGNIRLDGHGTVP----LGADQILLRGAQLRNTQWVH 264
Query: 262 GVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPY 321
G+ VYTG +TK+ N K S VE+ N +++ IL+ + VC+ +W +
Sbjct: 265 GIVVYTGHDTKLMQNSTSPPLKLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRR-H 323
Query: 322 NDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDK 381
+ + WY + +FL+F++LFN +IP+S+ VT+E+ KF ++FI+WD
Sbjct: 324 SGKDWYLNLNYGGASNFGL-----NFLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDL 378
Query: 382 DFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEV 441
D + E + A+ TS+LNEELGQV Y+F+DKTGTLT N M+F +C I G Y V +
Sbjct: 379 DMHYEPTDTAAMARTSNLNEELGQVKYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPE 438
Query: 442 D-------------GLSQTDGTLTYFDKVDKNREEL-----FLRALCLCHTVEIKTNDAV 483
D G +T + + + N FL + +CHT +
Sbjct: 439 DYGCSPDEWQNSQFGDEKTFSDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPER---- 494
Query: 484 DGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNF 543
E ++ Y ++SPDE ALV+ AK+ F F G + +++ +E E YELL+ L F
Sbjct: 495 ----EGDKIIYQAASPDEGALVRAAKQLNFVFTGRTPDSVIIDSLGQE-ERYELLNVLEF 549
Query: 544 DAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHEI--ELTKVHVERNAMDGYRTLCV 601
+ R+RMSVIV+T G + L+CKGAD+ ++ R+ E+T H+E+ A +G RTLC
Sbjct: 550 TSARKRMSVIVRTPSGKLRLYCKGADTVIYDRLAETSKYKEITLKHLEQFATEGLRTLCF 609
Query: 602 AFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAE 661
A EI+ D++ A ++Q+R K+E+ ++ IE N+ L+GATA+EDKLQDQ E
Sbjct: 610 AVAEISESDFQEWRAVYQRASTSVQNRLLKLEESYELIEKNLQLLGATAIEDKLQDQVPE 669
Query: 662 TIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHEL 721
TIE L A +K+W+LTGDK ETA + ++C+L + N ++ + +++ + R
Sbjct: 670 TIETLMKADIKIWILTGDKQETAINIGHSCKLLKKNMGMIVINEGSLDGTRETLSRHCTT 729
Query: 722 LIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQI 781
L + +K ++ LIIDG TL L + FL +
Sbjct: 730 LGDALRK------------------ENDFALIIDGKTLKYALTFG-------VRQYFLDL 764
Query: 782 CMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEG 841
+ C AV+CCR++PLQK+++V MVK + +TL+IGDGANDVSMI +HVG+GI G EG
Sbjct: 765 ALSCKAVICCRVSPLQKSEVVEMVKK-QVKVVTLAIGDGANDVSMIQTAHVGVGISGNEG 823
Query: 842 RQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFS 901
QAA +SDYS+ +FK+LK LL+ HG Y R++ + Y FYKN+ + + + F GFS
Sbjct: 824 LQAANSSDYSIAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFS 883
Query: 902 QQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLY 961
Q L++ + +YN+ FT++P L + E+ + + P LY K S NA L ++
Sbjct: 884 GQILFERWCIGLYNVMFTAMPPLTLGIFERSCRKENMLKYPELY-KTSQNA-LDFNTKVF 941
Query: 962 WTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTR 1019
W F + F+ Q + NGK G V+T +V TV LK L+T
Sbjct: 942 WVHCLNGLFHSVILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETS 1001
Query: 1020 FWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ-QRMYFVFAQMLSSVSTWLAIILLIF 1078
+WTW +H IWGS+A +V F + +WP + M A + SS W+ ++ +
Sbjct: 1002 YWTWFSHIAIWGSIALWVVFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPV 1060
Query: 1079 ISLFPEILLIVLK 1091
SL +++ V+K
Sbjct: 1061 ASLLLDVVYKVIK 1073
>gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo
sapiens]
Length = 1223
Score = 634 bits (1634), Expect = 0.0
Identities = 372/1088 (34%), Positives = 581/1088 (53%), Gaps = 65/1088 (5%)
Query: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
++ N I +SKY + FLP NLFEQF+ +AN YFL + ++Q+ + S T+ +PL
Sbjct: 61 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 120
Query: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
V+T+TA+K +D+ RH++DN+VN ++ N +++ + VGD+++++ ++
Sbjct: 121 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 180
Query: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
DL+LLSS G CY+ TA LDGE+N K A+ T L + + CE P
Sbjct: 181 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 240
Query: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
L KF G + N L +N+LL+G L+NTE +G+ ++ G +TK+ N
Sbjct: 241 LDKFSGTLYWKENKFP-----LSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 295
Query: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDE----PWYNQKTQKERE 336
KR+++++ +N ++ L+ + +W+ PW E
Sbjct: 296 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 349
Query: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNT 396
F F S++++ N ++P+S+YV+VE+ + S+FI+WDK + + A T
Sbjct: 350 DSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDKKMFCMKKRTPAEART 409
Query: 397 SDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQ---------- 446
+ LNEELGQV+Y+F+DKTGTLT+N M F +C I+GH Y V + ++
Sbjct: 410 TTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDVLGHKAELGERPEPVDF 469
Query: 447 -----TDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTY 494
D ++D K+ F R L LCHTV + + EL Y
Sbjct: 470 SFNPLADKKFLFWDPSLLEAVKIGDPHTHEFFRLLSLCHTVMSEEKN-------EGELYY 522
Query: 495 ISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIV 554
+ SPDE ALV A+ +GF F + V I Y+LL L+F+ +R+RMSVIV
Sbjct: 523 KAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAIT-YQLLAILDFNNIRKRMSVIV 581
Query: 555 KTQEGDILLFCKGADSAVFPRVQNHEIEL---TKVHVERNAMDGYRTLCVAFKEIAPDDY 611
+ EG I L+CKGAD+ + R+ + EL T H+ A +G RTL +A+K++ + Y
Sbjct: 582 RNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLAYKDLDEEYY 641
Query: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
E + ++A +A RE+++ +++++E NM L+GATA+EDKLQ ETI L A +
Sbjct: 642 EEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPETIALLTLANI 701
Query: 672 KVWVLTGDKMETAKSTCYACRLFQTN-TELLELTTKTIEESERKEDRLHELLIEYRKKLL 730
K+WVLTGDK ETA + Y+C++ + TE+ +T T+ E + + E +++ + +
Sbjct: 702 KIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAREKMMDSSRSVG 761
Query: 731 HEFPKSTRSFKKAWTE-----HQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKC 785
+ F + T EY L+I+G +L+ L + + FL+ C
Sbjct: 762 NGFTYQDKLSSSKLTSVLEAVAGEYALVINGHSLAHALEADMELE-------FLETACAC 814
Query: 786 TAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
AV+CCR+ PLQKAQ+V +VK K + +TL+IGDGANDVSMI +H+G+GI G+EG QA
Sbjct: 815 KAVICCRVTPLQKAQVVELVKKYKKA-VTLAIGDGANDVSMIKTAHIGVGISGQEGIQAV 873
Query: 846 RNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPL 905
SDYS +FK L++LLL HG Y+R+ + YFFYKN F + F + FFCGFS Q +
Sbjct: 874 LASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYKNFAFTMVHFWFGFFCGFSAQTV 933
Query: 906 YDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYWTFL 965
YD ++T+YNI +TSLP+LA + +Q + P+LY N + F
Sbjct: 934 YDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPKLYEPGQLNLLFNKREFFICIAQ 993
Query: 966 AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWTWIN 1025
+ + FF Y +F A+ ++ ++ +F V T LV V++++ LDT +WT IN
Sbjct: 994 GIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVATSLVIVVSVQIGLDTGYWTAIN 1053
Query: 1026 HFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFISLFP 1083
HF IWGSLA Y + F+ G+ F Q R L+ + WL I+L + + P
Sbjct: 1054 HFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQNTLAQPTVWLTIVLTTVVCIMP 1113
Query: 1084 EILLIVLK 1091
+ L+
Sbjct: 1114 VVAFRFLR 1121
>gi|50083277 ATPase class I type 8B member 4 [Homo sapiens]
Length = 1192
Score = 632 bits (1629), Expect = 0.0
Identities = 378/1091 (34%), Positives = 584/1091 (53%), Gaps = 69/1091 (6%)
Query: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100
++ DNRI +SKY + FLP NLFEQF+R+AN YFL + ++Q+ + + T+ +PL
Sbjct: 27 QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVL 86
Query: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
VIT+TA+K +D+ RH++DN+VN ++ N+K ++ +KVGD+++++ ++
Sbjct: 87 VITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAA 146
Query: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIAL-CTAESIDTLRAAIECEQPQP 219
DL+LLSS G CYV TA LDGE+N K +A+ T L + + CE P
Sbjct: 147 DLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNN 206
Query: 220 DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279
L KF+G + S + SL E ++L+G L+NT +G+ ++ G +TK+ N
Sbjct: 207 KLDKFMGIL-----SWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGK 261
Query: 280 KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339
KR+++++ +N ++ L+ + +W+S + + E E
Sbjct: 262 TKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ--TGDQFRTFLFWNEGEKSS 319
Query: 340 VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399
V F F S++++ N ++P+S+YV+VE+ + S+FI+WD+ Y A+ T+ L
Sbjct: 320 VFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTL 379
Query: 400 NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDG---------------L 444
NEELGQ++Y+F+DKTGTLT+N M F C I+G Y V ++D
Sbjct: 380 NEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDLDQKTEITQEKEPVDFSVK 439
Query: 445 SQTDGTLTYFD-------KVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISS 497
SQ D +FD K+ + FLR L LCHTV + N A EL Y
Sbjct: 440 SQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSA-------GELIYQVQ 492
Query: 498 SPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQ 557
SPDE ALV A+ +GF F + +E + + Y+LL L+F+ R+RMSVIV+
Sbjct: 493 SPDEGALVTAARNFGFIFKSRTPETITIE-ELGTLVTYQLLAFLDFNNTRKRMSVIVRNP 551
Query: 558 EGDILLFCKGADSAVFPRVQNHE---IELTKVHVERNAMDGYRTLCVAFKEIAPDDYERI 614
EG I L+ KGAD+ +F ++ + LT H+ A +G RTL +A++++ ++
Sbjct: 552 EGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEW 611
Query: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
++ L +A A ++R+E++ ++++IE ++ L+GATAVEDKLQ+ ET+ +L A +K+W
Sbjct: 612 HKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIW 671
Query: 675 VLTGDKMETAKSTCYACRLF--QTNTELLELTTKTIEESERKEDRLHELLIEYR------ 726
VLTGDK ETA + YAC + N + +E E L + R
Sbjct: 672 VLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQNRNFSNGH 731
Query: 727 ----KKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQIC 782
KK E T +Y LII+G +L+ L S + K+ L++
Sbjct: 732 VVCEKKQQLELDSIVEE-----TITGDYALIINGHSLAHALES-------DVKNDLLELA 779
Query: 783 MKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGR 842
C V+CCR+ PLQKAQ+V +VK + + +TL+IGDGANDVSMI +H+G+GI G+EG
Sbjct: 780 CMCKTVICCRVTPLQKAQVVELVKKYRNA-VTLAIGDGANDVSMIKSAHIGVGISGQEGL 838
Query: 843 QAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQ 902
QA SDYS +F++L++LLL HG Y R+ + YFFYKN F L F + FFCGFS
Sbjct: 839 QAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSA 898
Query: 903 QPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNAMLQLGPFLYW 962
Q +YD ++T++NI +TSLP+LA + +Q ++ P+LY N + F
Sbjct: 899 QTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFIC 958
Query: 963 TFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTLKLALDTRFWT 1022
+ V FF Y F + E+ + +F + T LV V++++ALDT +WT
Sbjct: 959 VLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWT 1018
Query: 1023 WINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVSTWLAIILLIFIS 1080
+INH IWGS+A Y + F+ GI F Q L+ WL I+L S
Sbjct: 1019 FINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVAS 1078
Query: 1081 LFPEILLIVLK 1091
+ P + LK
Sbjct: 1079 VMPVVAFRFLK 1089
>gi|117168245 ATPase, aminophospholipid transporter-like, Class I,
type 8A, member 2 [Homo sapiens]
Length = 1188
Score = 622 bits (1605), Expect = e-178
Identities = 392/1107 (35%), Positives = 586/1107 (52%), Gaps = 79/1107 (7%)
Query: 15 GEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFY 74
G++ RT+++ ++ +F DN+I ++KY++ FLP+ L+EQ RR AN +
Sbjct: 48 GDQLEAPARTIYLNQPHLN--------KFRDNQISTAKYSVLTFLPRFLYEQIRRAANAF 99
Query: 75 FLIIFLVQVTVD-TPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIEN 133
FL I L+Q D +PT T+ +PL ++T+ IK+ ED+ RH+ADN VNK ++ N
Sbjct: 100 FLFIALLQQIPDVSPTGRYTTLVPLIIILTIAGIKEIVEDFKRHKADNAVNKKKTIVLRN 159
Query: 134 AKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAV 193
+++ VGD+V+V + P D++LLSS CYV TA+LDGE+N K +
Sbjct: 160 GMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLSSSEPQAMCYVETANLDGETNLKIRQGL 219
Query: 194 RDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGAT 253
T + T E + L IECE P LY F G +N+ SL A LGP+ +LL+G
Sbjct: 220 SHTADMQTREVLMKLSGTIECEGPNRHLYDFTGNLNLDGKSLVA----LGPDQILLRGTQ 275
Query: 254 LKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK 313
L+NT+ ++G+ VYTG +TK+ N KRS VEK N ++V ILL A V +
Sbjct: 276 LRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEKVTNVQILVLFGILLVMALVSSAGA 335
Query: 314 YVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLG 373
W + + ++ WY +K + + L+F++L+N +IP+S+ VT+E+ K+
Sbjct: 336 LYWNRS-HGEKNWYIKKMDTTSDNFGY-----NLLTFIILYNNLIPISLLVTLEVVKYTQ 389
Query: 374 SFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHK 433
+ FI+WD D Y + A+ TS+LNEELGQV Y+F+DKTGTLT N M F +C I G
Sbjct: 390 ALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDKTGTLTCNIMNFKKCSIAGVT 449
Query: 434 YKGVTQEVDGLSQTD--------GTLTYFD--KVDKNREEL---------FLRALCLCHT 474
Y + S D FD ++ KN E+ FL L +CHT
Sbjct: 450 YGHFPELAREPSSDDFCRMPPPCSDSCDFDDPRLLKNIEDRHPTAPCIQEFLTLLAVCHT 509
Query: 475 VEIKTNDAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEE 534
V + + + Y +SSPDE ALVKGAK+ GF F + +E +E +
Sbjct: 510 VVPE--------KDGDNIIYQASSPDEAALVKGAKKLGFVFTARTPFSVIIEAMGQE-QT 560
Query: 535 YELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFPRVQNHE--IELTKVHVERNA 592
+ +L+ L F + R+RMSVIV+T G + L+CKGAD+ +F R+ +E T H+E A
Sbjct: 561 FGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKDSKYMEETLCHLEYFA 620
Query: 593 MDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVE 652
+G RTLCVA+ +++ ++YE + EA L+DR +++E+ ++ IE N+ L+GATA+E
Sbjct: 621 TEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYEIIEKNLLLLGATAIE 680
Query: 653 DKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE 712
D+LQ ETI L A +K+WVLTGDK ETA + Y+CRL N L+ L
Sbjct: 681 DRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQNMALILL--------- 731
Query: 713 RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQDSSSN 772
KED L + + + LIIDG TL L S
Sbjct: 732 -KEDSLDATRA--------AITQHCTDLGNLLGKENDVALIIDGHTLKYAL-------SF 775
Query: 773 NYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMILESHV 832
+ FL + + C AV+CCR++PLQK++IV +VK + ITL+IGDGANDV MI +HV
Sbjct: 776 EVRRSFLDLALSCKAVICCRVSPLQKSEIVDVVKK-RVKAITLAIGDGANDVGMIQTAHV 834
Query: 833 GIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFILPQF 892
G+GI G EG QA NSDY++ +F +L+KLLL HG Y R+ + Y FYKN+ + +
Sbjct: 835 GVGISGNEGMQATNNSDYAIAQFSYLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIEL 894
Query: 893 LYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKISGNA 952
+ F GFS Q L++ + +YN+ FT+LP + E+ +++ P+LY
Sbjct: 895 WFAFVNGFSGQILFERWCIGLYNVIFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGE 954
Query: 953 MLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVFTVTL 1012
F A + F+ + ++ +G G IV+T +V TV L
Sbjct: 955 GFNTKVFWGHCINALVHSLILFWFPMKALEHDTVLTSGHATDYLFVGNIVYTYVVVTVCL 1014
Query: 1013 KLALDTRFWTWINHFVIWGS-LAFYVFFSFFWGGIIWPFLK-QQRMYFVFAQMLSSVSTW 1070
K L+T WT +H +WGS L + VFF + IWP + M +LSS W
Sbjct: 1015 KAGLETTAWTKFSHLAVWGSMLTWLVFFGIY--STIWPTIPIAPDMRGQATMVLSSAHFW 1072
Query: 1071 LAIILLIFISLFPEILLIVLKNVRRRS 1097
L + L+ L ++ K+ +++
Sbjct: 1073 LGLFLVPTACLIEDVAWRAAKHTCKKT 1099
>gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens]
Length = 1251
Score = 595 bits (1533), Expect = e-169
Identities = 370/1110 (33%), Positives = 594/1110 (53%), Gaps = 101/1110 (9%)
Query: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100
++ +N I + KY + F+P NLFEQF+R AN YFL + ++Q T T+ +PL
Sbjct: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150
Query: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
V+ VTAIK +D RH+ D E+N T +I++ + + ++I+VGDV+ ++ ++ P
Sbjct: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210
Query: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAE-SIDTLRAAIECEQPQP 219
D++LLSS + CYV TA LDGE+N K ++ T E ++ T IECE+P
Sbjct: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270
Query: 220 DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279
L KF G + + S L + +LL+G ++NT+ +G+ ++ G +TK+ N
Sbjct: 271 RLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325
Query: 280 KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339
KR+ ++ +N +++ +F++L + + + + + WY + + + +
Sbjct: 326 TRFKRTKIDYLMN-YMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR 384
Query: 340 VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399
F F ++++ N ++P+S+YV+VE+ + S FI+WD Y E + A T+ L
Sbjct: 385 G---FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441
Query: 400 NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY----------KGVTQEVDGLSQT-- 447
NE+LGQ+ Y+F+DKTGTLT+N M F +CCI+G Y ++VD T
Sbjct: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYA 501
Query: 448 DGTLTYFD-----KVDKNRE---ELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSP 499
DG L ++D ++ +E F L +CHTV + D DG +L Y ++SP
Sbjct: 502 DGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDG-----QLNYQAASP 553
Query: 500 DEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEG 559
DE ALV A+ +GF FL + + E Y +L L+F++ R+RMS+IV+T EG
Sbjct: 554 DEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMSIIVRTPEG 612
Query: 560 DILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGY-----RTLCVAFKEIAPDDYERI 614
+I L+CKGAD+ ++ R+ H + TK + +A+D + RTLC+ +KEI ++
Sbjct: 613 NIKLYCKGADTVIYERL--HRMNPTKQETQ-DALDIFANETLRTLCLCYKEIEEKEFTEW 669
Query: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674
N++ + A +A +R+E ++KV+++IE ++ L+GATA+EDKLQD ETI L A +K+W
Sbjct: 670 NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729
Query: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKK--LLHE 732
VLTGDK ETA++ +AC L +T TI E LH + R + + +
Sbjct: 730 VLTGDKKETAENIGFACELLTEDT--------TICYGEDINSLLHARMENQRNRGGVYAK 781
Query: 733 F-PKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQ------------------------ 767
F P SF + LII GS L+ IL +
Sbjct: 782 FAPPVQESF---FPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838
Query: 768 ----DSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAND 823
++ + F+ + +C+AV+CCR+ P QKA +V +VK K ITL+IGDGAND
Sbjct: 839 KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYK-KAITLAIGDGAND 897
Query: 824 VSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYK 883
V+MI +H+G+GI G+EG QA +SDYS +F++L++LLL HG Y+R+ ++YFFYK
Sbjct: 898 VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957
Query: 884 NLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPR 943
N F L F Y FF G+S Q Y+ ++T+YN+ +TSLP+L LL+Q ++ P
Sbjct: 958 NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017
Query: 944 LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFF---GTYFLFQTASLEENGKVYGNW-TFG 999
LY+ + + F + FF G Y ++ ++G+ ++ +F
Sbjct: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDYQSFA 1073
Query: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMY 1057
+ + LV TV ++ LDT +WT++N F I+GS+A Y + F F GI F +
Sbjct: 1074 VTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFT 1133
Query: 1058 FVFAQMLSSVSTWLAIILLIFISLFPEILL 1087
+ L WL IIL + + L P + +
Sbjct: 1134 GTASNALRQPYIWLTIILTVAVCLLPVVAI 1163
>gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens]
Length = 1300
Score = 517 bits (1332), Expect = e-146
Identities = 346/1120 (30%), Positives = 568/1120 (50%), Gaps = 110/1120 (9%)
Query: 41 QRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSPVTS-GLPLF 99
+++ N I ++KY ++FLP NL+EQF R++N +FLII ++Q D T P S P+
Sbjct: 131 KKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNLFFLIIIILQSIPDISTLPWFSLSTPMV 190
Query: 100 FVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFP 159
++ + A + +D RH++D +N I+ +K+ + + VGDVV ++ D P
Sbjct: 191 CLLFIRATRDLVDDMGRHKSDRAINNRPCQILMGKSFKQKKWQDLCVGDVVCLRKDNIVP 250
Query: 160 CDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA-LCTAESIDTLRAAIECEQPQ 218
D++LL+S CYV T +DGE+N K A+ T L T + + + + + CE P
Sbjct: 251 ADMLLLASTEPSSLCYVETVDIDGETNLKFRQALMVTHKELATIKKMASFQGTVTCEAPN 310
Query: 219 PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
++ FVG + SL NLLL+G ++NT+ YG+ +Y G +TK+ N
Sbjct: 311 SRMHHFVGCLEWNDKKY-----SLDIGNLLLRGCRIRNTDTCYGLVIYAGFDTKIMKNCG 365
Query: 279 GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
KR+ ++ +N L+V +FI + + + + + D +Y
Sbjct: 366 KIHLKRTKLDLLMNK-LVVVIFISVVLVCLVLAFGFGFSVKEFKDHHYYLSGVHGSSVAA 424
Query: 339 KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
+ F F SF++L + IP+SM++ E S FI WD Y + + A ++
Sbjct: 425 E---SFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWDVQMYYKPQDVPAKARSTS 481
Query: 399 LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT--------DGT 450
LN+ LGQV+Y+F+DKTGTLT+N + F +CCI G Y ++ + DG
Sbjct: 482 LNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEATTRPKENPYLWNKFADGK 541
Query: 451 LTYFDK-----VDKNREEL---FLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEI 502
L + + V N +E F R L +CHTV ++ + +L Y ++SPDE
Sbjct: 542 LLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRESPR----ERPDQLLYQAASPDEG 597
Query: 503 ALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDIL 562
ALV A+ +G+ FL + + +E Y++L ++F++ R+RMSV+V+ EG I
Sbjct: 598 ALVTAARNFGYVFLSRTQDTVTIMELGEE-RVYQVLAIMDFNSTRKRMSVLVRKPEGAIC 656
Query: 563 LFCKGADSAVFPRVQNHEIE--LTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
L+ KGAD+ +F R+ T+ + A + RTLC+A++E+A D YE ++ E
Sbjct: 657 LYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLAYREVAEDIYEDWQQRHQE 716
Query: 621 AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
A + LQ+R + +++ L+GATA+ED+LQD ETI+ L + +K+WVLTGDK
Sbjct: 717 ASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPETIKCLKKSNIKIWVLTGDK 766
Query: 681 METAKSTCYACRLFQTNTELLE------------------LTTKTIEESER----KEDRL 718
ETA + +AC L N +LE LT +++ + + D L
Sbjct: 767 QETAVNIGFACELLSENMLILEEKEISRILETYWENSNNLLTRESLSQVKLALVINGDFL 826
Query: 719 HELLIEYRKK------------LLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSS 766
+LL+ RK+ E +S R F A + L+ L L +
Sbjct: 827 DKLLVSLRKEPRALAQNVNMDEAWQELGQSRRDFLYA----RRLSLLCRRFGLPLAAPPA 882
Query: 767 QDSSSNNYKSI-----FLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGA 821
QDS + + F+ + KC AV+CCR+ P QKA IV +VK +TL+IGDGA
Sbjct: 883 QDSRARRSSEVLQERAFVDLASKCQAVICCRVTPKQKALIVALVKKYH-QVVTLAIGDGA 941
Query: 822 NDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFF 881
ND++MI + VG+G+ G+EG QA +NSD+ + +F L++LLL HG YVRI ++YFF
Sbjct: 942 NDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCFLQRLLLVHGRWSYVRICKFLRYFF 1001
Query: 882 YKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSD 941
YK++ ++ Q + + GF+ QPLY+ +L ++N+ +++LP+L L EQ ++ +
Sbjct: 1002 YKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLLYSTLPVLYIGLFEQDVSAEQSLEK 1061
Query: 942 PRLYMKISGNAMLQLGPFLYWTFLAAF-EGTVFFFGTYFLFQTASLEENG--KVYGNWTF 998
P LY+ + + F YW F+ A G +F+ S + G + +F
Sbjct: 1062 PELYVVGQKDEL-----FNYWVFVQAIAHGVTTSLVNFFMTLWISRDTAGPASFSDHQSF 1116
Query: 999 GTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV--------FFSFFWGGIIWPF 1050
+V + ++T+++ L ++WT + I SL FY F+ F +PF
Sbjct: 1117 AVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYAIMTTTTQSFWLFRVSPTTFPF 1176
Query: 1051 LKQQRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVL 1090
L + ++SS S L ++L + I+ FP + L V+
Sbjct: 1177 L------YADLSVMSSPSILLVVLLSVSINTFPVLALRVI 1210
>gi|65301139 ATPase, class II, type 9A [Homo sapiens]
Length = 1047
Score = 445 bits (1144), Expect = e-124
Identities = 327/1108 (29%), Positives = 528/1108 (47%), Gaps = 126/1108 (11%)
Query: 13 CAGEEKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIAN 72
C G E R RTV++G HP QR+ N I + KY + FLP LF QF+ N
Sbjct: 31 CGGGEAR--PRTVWLG-HPEKRD-----QRYPRNVINNQKYNFFTFLPGVLFNQFKYFFN 82
Query: 73 FYFLIIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYII 131
YFL++ Q + + T +PL FV+ VT I++ E+ + D EVN +
Sbjct: 83 LYFLLLACSQFVPEMRLGALYTYWVPLGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRL 142
Query: 132 ENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHY 191
V+ +S I+VGD++ V+ ++ P D+I L + +G+C++ T LDGE++ K
Sbjct: 143 TARGTVKVKSSNIQVGDLIIVEKNQRVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRL 202
Query: 192 AVRDTIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKG 251
V T L TA + +R+ + E+P D++ FVG +S ++ SL EN L G
Sbjct: 203 PVACTQRLPTAADLLQIRSYVYAEEPNIDIHNFVGTFT-REDSDPPISESLSIENTLWAG 261
Query: 252 ATLKNTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTT 311
T+ + + GV +YTG E + +N K + +N + L+ + V
Sbjct: 262 -TVVASGTVVGVVLYTGRELRSVMNTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMVA 320
Query: 312 LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKF 371
L++ WY Q + F++LF+ IIP+S+ V ++M K
Sbjct: 321 LQHFAGR-------WYLQ-----------------IIRFLLLFSNIIPISLRVNLDMGKI 356
Query: 372 LGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC--- 428
+ S+ I D G +V +S + E+LG++ Y+ TDKTGTLT+N M F
Sbjct: 357 VYSWVIRRDSKI------PGTVVRSSTIPEQLGRISYLLTDKTGTLTQNEMIFKRLHLGT 410
Query: 429 ----------IDGHKYKGVTQEV-DGLSQTDGTLTY-FDKVDKNREELFLRALCLCHTVE 476
+ H + TQ+ D +Q TLT + +R ++A+ LCH V
Sbjct: 411 VAYGLDSMDEVQSHIFSIYTQQSQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVT 470
Query: 477 --IKTNDAVDGAT-----ESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQR 529
++N D A E + Y +SSPDE+ALV+ + G T +G M++
Sbjct: 471 PVYESNGVTDQAEAEKQYEDSCRVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPG 530
Query: 530 KEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNHEIELTKVHV 588
+I + +L F +RM +IV+ + G+I + KGAD + VQ ++ +
Sbjct: 531 DQILNFTILQIFPFTYESKRMGIIVRDESTGEITFYMKGADVVMAGIVQYND--WLEEEC 588
Query: 589 ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGA 648
A +G R L VA K +A + Y+ + ++AK+++ DR K+ V + +E M L+
Sbjct: 589 GNMAREGLRVLVVAKKSLAEEQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCL 648
Query: 649 TAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTI 708
T VED+LQ T+E L AG+KVW+LTGDK+ETA T L N ++ T
Sbjct: 649 TGVEDQLQADVRPTLETLRNAGIKVWMLTGDKLETATCTAKNAHLVTRNQDIHVFRLVT- 707
Query: 709 EESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
H L +R+K + L+I G +L + L
Sbjct: 708 -----NRGEAHLELNAFRRK-------------------HDCALVISGDSLEVCLKY--- 740
Query: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
Y+ F+++ +C AV+CCR AP QKAQIVR+++ G +T ++GDG NDVSMI
Sbjct: 741 -----YEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGK-LTCAVGDGGNDVSMIQ 794
Query: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
ES G+G++GKEG+QA+ +D+S+ +FKHL +LL+ HG Y R A L Q+ +++LC
Sbjct: 795 ESDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIS 854
Query: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
Q ++ F+ PLY + Y+ +T P+ + +L++ + + P LY +
Sbjct: 855 TMQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELYKDL 913
Query: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
L FL W ++ ++G+ +G LF++ + I FT L+
Sbjct: 914 LKGRPLSYKTFLIWVLISIYQGSTIMYGALLLFESEFVH----------IVAISFTSLIL 963
Query: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
T L +AL + W W+ SLA Y+ ++ FL + F+ ++++S
Sbjct: 964 TELLMVALTIQTWHWLMTVAELLSLACYI------ASLV--FLHE----FIDVYFIATLS 1011
Query: 1069 TWLAIILLIFISLFPEILLIVLKNVRRR 1096
+ ++ +S P L VLK +RRR
Sbjct: 1012 FLWKVSVITLVSCLP---LYVLKYLRRR 1036
>gi|41327760 ATPase, class II, type 9B [Homo sapiens]
Length = 1147
Score = 412 bits (1059), Expect = e-115
Identities = 314/1121 (28%), Positives = 526/1121 (46%), Gaps = 135/1121 (12%)
Query: 17 EKRVGTRTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFL 76
+K + RTV++G E ++ N I + KY ++ F+P L+EQF+ N YFL
Sbjct: 110 KKELKARTVWLGCPEKCE------EKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFL 163
Query: 77 IIFLVQVTVDTPTSPV-TSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAK 135
+I Q + T PL FV+ VT ++ +++ R + D EVN +
Sbjct: 164 VISCSQFVPALKIGYLYTYWAPLGFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRG 223
Query: 136 RVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRD 195
+V+ +S I+VGD++ V+ ++ P D++ L + G+C++ T LDGE++ K AV
Sbjct: 224 KVQVKSSDIQVGDLIIVEKNQRIPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSC 283
Query: 196 TIALCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLK 255
T L + ++ A + ++PQ D++ F G +S + SL EN L +T+
Sbjct: 284 TQQLPALGDLFSISAYVYAQKPQMDIHSFEGTFT-REDSDPPIHESLSIENTLW-ASTIV 341
Query: 256 NTEKIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLK-Y 314
+ + GV +YTG ET+ +N K ++ +N L+ + V TL+ +
Sbjct: 342 ASGTVIGVVIYTGKETRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF 401
Query: 315 VWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGS 374
V PWY + F++LF++IIP+S+ V ++M K +
Sbjct: 402 VG--------PWYR-----------------NLFRFLLLFSYIIPISLRVNLDMGKAVYG 436
Query: 375 FFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
+ + D++ G +V TS + EELG++ Y+ TDKTGTLT+N M F + Y
Sbjct: 437 WMMMKDENI------PGTVVRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSY 490
Query: 435 KGVTQEV----------DGLSQTDGTLTYFDKVDK-------------NREELFLRALCL 471
T + SQ G T + K +R ++A+ L
Sbjct: 491 GADTMDEIQSHVRDSYSQMQSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVL 550
Query: 472 CHTVE--IKTNDAVDGATESAEL---------TYISSSPDEIALVKGAKRYGFTFLGNRN 520
CH V ++ V TE AE TY +SSPDE+ALV+ + G T +
Sbjct: 551 CHNVTPVYESRAGVTEETEFAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDL 610
Query: 521 GYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQE-GDILLFCKGADSAVFPRVQNH 579
M+++ ++ + +L F + +RM VIV+ + +I + KGAD A+ P VQ +
Sbjct: 611 TSMQLKTPSGQVLSFCILQLFPFTSESKRMGVIVRDESTAEITFYMKGADVAMSPIVQYN 670
Query: 580 EIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDI 639
+ + A +G RTL VA K + + Y+ + +AK+++ DR K+ V + +
Sbjct: 671 D--WLEEECGNMAREGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESL 728
Query: 640 ETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTE 699
E M L+ T VED+LQ T+E L AG+K+W+LTGDK+ETA + L + T+
Sbjct: 729 EREMELLCLTGVEDQLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLV-SRTQ 787
Query: 700 LLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTL 759
+ + + E H L +R+K + L+I G +L
Sbjct: 788 DIHIFRQVTSRGEA-----HLELNAFRRK-------------------HDCALVISGDSL 823
Query: 760 SLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGD 819
+ L Y+ F+++ +C AV+CCR +P QKA+IV +++ G T +IGD
Sbjct: 824 EVCLKY--------YEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRR-TCAIGD 874
Query: 820 GANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQY 879
G NDVSMI + GIGI+GKEG+QA+ +D+S+ +F+H+ +LL+ HG Y R A L Q+
Sbjct: 875 GGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSAALGQF 934
Query: 880 FFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLT 939
++ L Q ++ F+ PLY + Y +T P+ + +L+Q + +
Sbjct: 935 VMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVKPEMAM 993
Query: 940 SDPRLYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFG 999
P LY ++ L FL W ++ ++G + +G LF++ +
Sbjct: 994 LYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLFESEFVH----------VV 1043
Query: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYV----FFSFFWGGIIWPFLKQQR 1055
I FT L+ T L +AL R W W+ + SL YV F + ++G +
Sbjct: 1044 AISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFG-----IGRVSF 1098
Query: 1056 MYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLKNVRRR 1096
F+ +++V+ + + +S P L VLK +RR+
Sbjct: 1099 GAFLDVAFITTVTFLWKVSAITVVSCLP---LYVLKYLRRK 1136
>gi|149944474 ATPase, class V, type 10B [Homo sapiens]
Length = 1461
Score = 361 bits (926), Expect = 2e-99
Identities = 218/629 (34%), Positives = 333/629 (52%), Gaps = 38/629 (6%)
Query: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
E Y + SPDE ALV A Y FT + + V + + LL TL FD+VR+RM
Sbjct: 714 EFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRM 773
Query: 551 SVIVKTQ-EGDILLFCKGADSAVFPRVQ--------NHEIELTKV------HVERNAMDG 595
SV+V+ G+I+++ KGADS + ++ N E +L K+ H++ A DG
Sbjct: 774 SVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDG 833
Query: 596 YRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKL 655
RTLC+A K ++ +D+ R EA+ +L +R+E + + +E + L+GAT +ED+L
Sbjct: 834 LRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRL 893
Query: 656 QDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESE--- 712
Q+ +TI L AG+++WVLTGDK ETA + ++CRL + + T+ E E
Sbjct: 894 QEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESIL 953
Query: 713 ----RKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQD 768
+ + EL RK P T S E GL+IDG TL+ I +
Sbjct: 954 NCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVV-PEAGLVIDGKTLNAIFQGKLE 1012
Query: 769 SSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSMIL 828
FL++ C +VLCCR PLQK+ IV++V++ K +TLSIGDGANDVSMI
Sbjct: 1013 KK-------FLELTQYCRSVLCCRSTPLQKSMIVKLVRD-KLRVMTLSIGDGANDVSMIQ 1064
Query: 829 ESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLCFI 888
+ +GIGI G+EG QA +SD+++ +FKHLKKLLL HGH Y R+A +V Y+ YKN+C++
Sbjct: 1065 AADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYV 1124
Query: 889 LPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYMKI 948
F YQFFCGFS + D + +N+ FTSLP L + +L++ I+ +TL + P LY
Sbjct: 1125 NLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSG 1184
Query: 949 SGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFTVLVF 1008
+ L F A ++ + FF Y ++ + ++ +TFGT + T+ +
Sbjct: 1185 QNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDV-------FTFGTPINTISLT 1237
Query: 1009 TVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQMLSSVS 1068
T+ L A++ + WT + V+ GS Y S + Y+V LS+ +
Sbjct: 1238 TILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPT 1297
Query: 1069 TWLAIILLIFISLFPEILLIVLKNVRRRS 1097
+L L ++L P + L+ +S
Sbjct: 1298 FYLVCFLTPVVALLPRYFFLSLQGTCGKS 1326
Score = 253 bits (646), Expect = 7e-67
Identities = 148/416 (35%), Positives = 225/416 (54%), Gaps = 10/416 (2%)
Query: 23 RTVFVGNHPVSETEAYIAQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ 82
R VF N + +++R+ NR ++KYTL+ FLP+NLFEQF R AN YFL + ++
Sbjct: 46 RVVFPNNSIFHQDWEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILN 105
Query: 83 --VTVDTPTSPVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKR--VR 138
+++ +T LPL V+ V IK G ED+ RHR D +N S + I E ++ V+
Sbjct: 106 WMPSMEVFHREITM-LPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQ 164
Query: 139 KESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIA 198
K + ++VGD ++++ +E P D++LL S +G C++ TASLDGE+N K V+
Sbjct: 165 KCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQ 224
Query: 199 LCTAESIDTLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTE 258
+ I CE+P L KF G Y + G E+LLL+G T++NTE
Sbjct: 225 QEVQFEPELFHNTIVCEKPNNHLNKFKG----YMEHPDQTRTGFGCESLLLRGCTIRNTE 280
Query: 259 KIYGVAVYTGMETKMALNYQGKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQS 318
G+ +Y G ETK LN G KRS +E+ +N + + IL+ + +W
Sbjct: 281 MAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNG 340
Query: 319 TPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFIS 378
T + + P ++ L F FL+ ++L +IP+S+YV++E+ K FF+S
Sbjct: 341 T-FEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLS 399
Query: 379 WDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
D D YDEE + ++ E+LGQ+ Y+F+DKTGTLTEN M F C I G +Y
Sbjct: 400 NDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEY 455
>gi|222352161 ATPase, class V, type 10D [Homo sapiens]
Length = 1426
Score = 348 bits (893), Expect = 2e-95
Identities = 219/638 (34%), Positives = 336/638 (52%), Gaps = 53/638 (8%)
Query: 481 DAVDGATESAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHT 540
+++ G + L Y + SPDE ALV A+ Y T + V+ ++LLH
Sbjct: 710 ESLPGQPLACNLCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGPLTFQLLHI 769
Query: 541 LNFDAVRRRMSVIVKTQ-EGDILLFCKGADSAVFP-------------RVQNHEIELTKV 586
L FD+VR+RMSV+V+ ++++ KGADS + + Q E T+
Sbjct: 770 LPFDSVRKRMSVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQK 829
Query: 587 HVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLI 646
H++ A G RTLC+A K ++ +Y R A+ ++ +REE + + +E + L+
Sbjct: 830 HLDDYAKQGLRTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLL 889
Query: 647 GATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTK 706
GAT +ED+LQ+ E+IEALH AG+K+W+LTGDK ETA + YAC+L + + +L L T+
Sbjct: 890 GATGIEDRLQEGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPDDKLFILNTQ 949
Query: 707 T-----------IEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLIID 755
+ ++E ++K L E + L P+ + GLII
Sbjct: 950 SKDACGMLMSTILKELQKKTQALPEQVSLSEDLLQPPVPRDSGL---------RAGLIIT 1000
Query: 756 GSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITL 815
G TL L S FL++ C AV+CCR PLQK+++V++V++ +TL
Sbjct: 1001 GKTLEFALQESLQKQ-------FLELTSWCQAVVCCRATPLQKSEVVKLVRSHL-QVMTL 1052
Query: 816 SIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAH 875
+IGDGANDVSMI + +GIG+ G+EG QA SD++V +FKHL KLLL HGH Y R+++
Sbjct: 1053 AIGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSN 1112
Query: 876 LVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINI 935
++ YFFYKN+ ++ F YQFFCGFS + D L +N+ FTS P + Y +LE+ ++
Sbjct: 1113 MILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSA 1172
Query: 936 DTLTSDPRLYMKISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVY 993
+TL P LY SG P +W L A ++ V FF YF +Q G
Sbjct: 1173 ETLMQLPELYR--SGQKSEAYLPHTFWITLLDAFYQSLVCFFVPYFTYQ-------GSDT 1223
Query: 994 GNWTFGTIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQ 1053
+ FG + T +F V L L ++++ TWI+ VI GS+ Y F+ +G +
Sbjct: 1224 DIFAFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPP 1283
Query: 1054 QRMYFVFAQMLSSVSTWLAIILLIFISLFPEILLIVLK 1091
Y++ + + +L IL I+L P + VL+
Sbjct: 1284 SNPYWIMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQ 1321
Score = 248 bits (632), Expect = 3e-65
Identities = 147/431 (34%), Positives = 230/431 (53%), Gaps = 23/431 (5%)
Query: 43 FCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVT--VDTPTSPVTSGLPLFF 100
+ +NRI ++KYTL NF+P+NLFEQF R AN YFL + ++ V+ +T LPL
Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITM-LPLVV 129
Query: 101 VITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADETF 158
V+T+ AIK G ED+ +++ D ++N + VY + K + + + + VGD + + +E
Sbjct: 130 VLTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVI 189
Query: 159 PCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQ 218
P D++LL S DG C++ T+ LDGESN K VR + + + IECE P
Sbjct: 190 PADMVLLFSTDPDGICHIETSGLDGESNLKQRQVVRGYAEQDSEVDPEKFSSRIECESPN 249
Query: 219 PDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQ 278
DL +F G + +SN L ENLLL+G T++NTE + G+ VY G ETK LN
Sbjct: 250 NDLSRFRGFLE-HSNKERV---GLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNS 305
Query: 279 GKSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETL 338
G KRS +E+ N ++ + +L+ +W S Y ++N
Sbjct: 306 GPRYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSR-YEKMHFFNVPEPDGHIIS 364
Query: 339 KVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSD 398
+L F F + ++L +IP+S+YV++E+ K +FI D DFY+E+++ +
Sbjct: 365 PLLAGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALN 424
Query: 399 LNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY-------------KGVTQEVDGLS 445
+ E+LGQ+ Y+F+DKTGTLTEN M F C + G Y + V+++ D +
Sbjct: 425 IAEDLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENARRLESYQEAVSEDEDFID 484
Query: 446 QTDGTLTYFDK 456
G+L+ K
Sbjct: 485 TVSGSLSNMAK 495
>gi|14424433 ATPase, class V, type 10A [Homo sapiens]
Length = 1499
Score = 345 bits (885), Expect = 1e-94
Identities = 211/621 (33%), Positives = 338/621 (54%), Gaps = 46/621 (7%)
Query: 491 ELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRM 550
EL Y + SPDE ALV A+ Y + + + VE +ELLHTL FD+VR+RM
Sbjct: 690 ELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGRLTFELLHTLGFDSVRKRM 749
Query: 551 SVIVKTQEGD-ILLFCKGADSAVFPRVQ---------NHEIEL---TKVHVERNAMDGYR 597
SV+++ D I ++ KGADS V +Q H+ ++ T+ ++ A +G R
Sbjct: 750 SVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLR 809
Query: 598 TLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQD 657
TLC+A + ++ ++Y + +EA+ +L++ EE + + +ETN++L+GAT +ED+LQD
Sbjct: 810 TLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQD 869
Query: 658 QAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDR 717
ETI L AGL++WVLTGDK ETA + YAC+L + E++ L + E D
Sbjct: 870 GVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLD- 928
Query: 718 LHELLIEYRKKLLHEFPKSTRSF-----------KKAWTEHQEYGLIIDGSTLSLILNSS 766
+ L + + L P+ T+ + + L+IDG +L+ L
Sbjct: 929 --QCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDGRSLAYALEK- 985
Query: 767 QDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGANDVSM 826
N + FL + +C +VLCCR PLQK+ +V++V++ K +TL+IGDGANDVSM
Sbjct: 986 ------NLEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRS-KLKAMTLAIGDGANDVSM 1038
Query: 827 ILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYKNLC 886
I + VG+GI G+EG QA SD++VPKF++L++LL+ HGH Y R+A++V YFFYKN
Sbjct: 1039 IQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTM 1098
Query: 887 FILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPRLYM 946
F+ F +QFFCGFS + D YL +N+ F+SLP L +L++ + + L ++P+LY
Sbjct: 1099 FVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYK 1158
Query: 947 KISGNAMLQLGPFLYWTFL--AAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVFT 1004
SG M + P +W + AAF+ V F Y + ++++ +T+GT + T
Sbjct: 1159 --SGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVD-------LFTWGTPIVT 1209
Query: 1005 VLVFTVTLKLALDTRFWTWINHFVIWGSLAFYVFFSFFWGGIIWPFLKQQRMYFVFAQML 1064
+ + T L L ++T+ WTW+N S+ + + + Y+ +L
Sbjct: 1210 IALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALL 1269
Query: 1065 SSVSTWLAIILLIFISLFPEI 1085
+L ++ +L P +
Sbjct: 1270 GDPVFYLTCLMTPVAALLPRL 1290
Score = 264 bits (675), Expect = 3e-70
Identities = 151/401 (37%), Positives = 233/401 (58%), Gaps = 13/401 (3%)
Query: 40 AQRFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQ-VTVDTPTSPVTSGLPL 98
AQ DNR+ ++KYTL +FLPKNLFEQF R AN YF+ I L+ V P + P+
Sbjct: 56 AQHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPV 115
Query: 99 FFVITVTAIKQGYEDWLRHRADNEVNK--STVYIIENAKRVRKESEKIKVGDVVEVQADE 156
F++ +TA + +ED+ RHR+D+++N V+ E K V + ++I VGD V ++ +E
Sbjct: 116 LFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNE 175
Query: 157 TFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQ 216
FP D++LLSS DG C++ TA+LDGE+N K VR L + + T + IECE+
Sbjct: 176 IFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEK 235
Query: 217 PQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALN 276
P DL +F G I I+ N +A L ENLLL+G TL+NT+ + G+ +Y G ETK LN
Sbjct: 236 PNNDLSRFRGCI-IHDNGKKA---GLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLN 291
Query: 277 YQGKSQKRSAVEKSINAFLI--VYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKE 334
G KRS +E+ +N ++ V L + ++ + ++W+ Y ++ + +
Sbjct: 292 NSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWR---YQEKKSLFYVPKSD 348
Query: 335 RETLK-VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGAL 393
+L V FL+ +++ +IP+S+YV++E+ K +FI+ D YDEE +
Sbjct: 349 GSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQ 408
Query: 394 VNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY 434
++ E+LGQ+ Y+F+DKTGTLTEN M F C + G +Y
Sbjct: 409 CRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEY 449
>gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo
sapiens]
Length = 387
Score = 173 bits (439), Expect = 7e-43
Identities = 98/328 (29%), Positives = 169/328 (51%), Gaps = 16/328 (4%)
Query: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPT-SPVTSGLPLFF 100
++ N I +SKY + FLP NLFEQF+ +AN YFL + ++Q+ + S T+ +PL
Sbjct: 28 QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYFLFLLILQLIPQISSLSWFTTIVPLVL 87
Query: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160
V+T+TA+K +D+ RH++DN+VN ++ N +++ + VGD+++++ ++
Sbjct: 88 VLTITAVKDATDDYFRHKSDNQVNNRQSQVLINGILQQEQWMNVCVGDIIKLENNQFVAA 147
Query: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESIDTLRAAIECEQPQPD 220
DL+LLSS G CY+ TA LDGE+N K A+ T L + + CE P
Sbjct: 148 DLLLLSSSEPHGLCYIETAELDGETNMKVRQAIPVTSELGDISKLAKFDGEVICEPPNNK 207
Query: 221 LYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGK 280
L KF G + N L +N+LL+G L+NTE +G+ ++ G +TK+ N
Sbjct: 208 LDKFSGTLYWKENKF-----PLSNQNMLLRGCVLRNTEWCFGLVIFAGPDTKLMQNSGRT 262
Query: 281 SQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTP----YNDEPWYNQKTQKERE 336
KR+++++ +N ++ L+ + +W+ PW E
Sbjct: 263 KFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEHEVGMRFQVYLPW------DEAV 316
Query: 337 TLKVLKMFTDFLSFMVLFNFIIPVSMYV 364
F F S++++ N ++P+S+YV
Sbjct: 317 DSAFFSGFLSFWSYIIILNTVVPISLYV 344
>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
sapiens]
Length = 1170
Score = 85.1 bits (209), Expect = 3e-16
Identities = 136/661 (20%), Positives = 243/661 (36%), Gaps = 118/661 (17%)
Query: 95 GLPLFFVITVTAIKQGYEDW--------LRHRADNEVNKSTVYIIENAKRVRKESEKIKV 146
G + F + + + + DW L+ R + E S II N + ++ +I V
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFS---IIRNGQLIQLPVAEIVV 208
Query: 147 GDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID 206
GD+ +V+ + P D IL+ + +SL GES+ +D + L ++
Sbjct: 209 GDIAQVKYGDLLPADGILIQG----NDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVME 264
Query: 207 ----TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLG-PENLLLKGATLKNTEKIY 261
+ A+ + +G + + G PEN +N K
Sbjct: 265 GSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPEN--------RNKAKTQ 316
Query: 262 -GVAV-YTGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAAVCTT----- 311
GVA+ + ++ ++ + K +K V EKS+ + L + + KA + +
Sbjct: 317 DGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376
Query: 312 ---LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEM 368
L +V + N PW + T ++ + V F FII +++ V
Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPI-------------YIQYFVKF-FIIGITVLVVAVP 422
Query: 369 QKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC 428
+ + IS + + + LV D E +G + +DKTGTLT N M ++
Sbjct: 423 EGLPLAVTISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAY 481
Query: 429 IDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATE 488
I G Y+ + ++FL + I N A
Sbjct: 482 IGGIHYRQIPSP----------------------DVFLPKVLDLIVNGISINSAYTSKIL 519
Query: 489 SAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRR 548
E P ++ GF + Y V N E+ E +L F++VR+
Sbjct: 520 PPEKE--GGLPRQVGNKTECALLGFV-TDLKQDYQAVRN---EVPEEKLYKVYTFNSVRK 573
Query: 549 RMSVIVKTQEGDILLFCKGADSAVF--------------PRVQNHEIELTKVHVERNAMD 594
MS +++ G ++ KGA + P ++ + +E A D
Sbjct: 574 SMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633
Query: 595 GYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDK 654
G RT+C+A+++ DD E D E ++I T + I +ED
Sbjct: 634 GLRTICIAYRDF--DDTE-----------PSWDNE-------NEILTELTCIAVVGIEDP 673
Query: 655 LQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERK 714
++ + + I AG+ V ++TGD + TA++ C + + L L K R
Sbjct: 674 VRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRN 733
Query: 715 E 715
E
Sbjct: 734 E 734
>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
sapiens]
Length = 1205
Score = 85.1 bits (209), Expect = 3e-16
Identities = 136/661 (20%), Positives = 243/661 (36%), Gaps = 118/661 (17%)
Query: 95 GLPLFFVITVTAIKQGYEDW--------LRHRADNEVNKSTVYIIENAKRVRKESEKIKV 146
G + F + + + + DW L+ R + E S II N + ++ +I V
Sbjct: 152 GAAILFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFS---IIRNGQLIQLPVAEIVV 208
Query: 147 GDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID 206
GD+ +V+ + P D IL+ + +SL GES+ +D + L ++
Sbjct: 209 GDIAQVKYGDLLPADGILIQG----NDLKIDESSLTGESDHVKKSLDKDPMLLSGTHVME 264
Query: 207 ----TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLG-PENLLLKGATLKNTEKIY 261
+ A+ + +G + + G PEN +N K
Sbjct: 265 GSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKKGKKQGVPEN--------RNKAKTQ 316
Query: 262 -GVAV-YTGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAAVCTT----- 311
GVA+ + ++ ++ + K +K V EKS+ + L + + KA + +
Sbjct: 317 DGVALEIQPLNSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVF 376
Query: 312 ---LKYVWQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEM 368
L +V + N PW + T ++ + V F FII +++ V
Sbjct: 377 ILILYFVIDNFVINRRPWLPECTPI-------------YIQYFVKF-FIIGITVLVVAVP 422
Query: 369 QKFLGSFFISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECC 428
+ + IS + + + LV D E +G + +DKTGTLT N M ++
Sbjct: 423 EGLPLAVTISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAY 481
Query: 429 IDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATE 488
I G Y+ + ++FL + I N A
Sbjct: 482 IGGIHYRQIPSP----------------------DVFLPKVLDLIVNGISINSAYTSKIL 519
Query: 489 SAELTYISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRR 548
E P ++ GF + Y V N E+ E +L F++VR+
Sbjct: 520 PPEKE--GGLPRQVGNKTECALLGFV-TDLKQDYQAVRN---EVPEEKLYKVYTFNSVRK 573
Query: 549 RMSVIVKTQEGDILLFCKGADSAVF--------------PRVQNHEIELTKVHVERNAMD 594
MS +++ G ++ KGA + P ++ + +E A D
Sbjct: 574 SMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACD 633
Query: 595 GYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDK 654
G RT+C+A+++ DD E D E ++I T + I +ED
Sbjct: 634 GLRTICIAYRDF--DDTE-----------PSWDNE-------NEILTELTCIAVVGIEDP 673
Query: 655 LQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERK 714
++ + + I AG+ V ++TGD + TA++ C + + L L K R
Sbjct: 674 VRPEVPDAIAKCKQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRN 733
Query: 715 E 715
E
Sbjct: 734 E 734
>gi|66932949 ATPase type 13A4 [Homo sapiens]
Length = 1196
Score = 83.2 bits (204), Expect = 1e-15
Identities = 136/673 (20%), Positives = 267/673 (39%), Gaps = 126/673 (18%)
Query: 404 GQVDYVFTDKTGTLTENSMEF---IECCIDGHKYKGVTQEVDGLSQTDGTLTYFDKVDKN 460
GQ++ V DKTGTLT + ++ + C D + ++ V G + G L
Sbjct: 478 GQLNLVCFDKTGTLTRDGLDLWGVVSC--DRNGFQEVHSFASGQALPWGPLC-------- 527
Query: 461 REELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIAL------VKGAKRYGFT 514
A+ CH++ I + + G + +L ++ E+A +KG +
Sbjct: 528 ------AAMASCHSL-ILLDGTIQG--DPLDLKMFEATTWEMAFSGDDFHIKGVPAHAMV 578
Query: 515 FLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGADSAVFP 574
R + +E +LH F + +RM+VIV+ GD L F KGA V
Sbjct: 579 VKPCRTA------SQVPVEGIAILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERVAS 632
Query: 575 RVQNHEIELTKV-HVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKME 633
Q + + V ++ G+R + +A+K++ D + +
Sbjct: 633 FCQPETVPTSFVSELQIYTTQGFRVIALAYKKLENDHHATTLTR---------------- 676
Query: 634 KVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRL 693
+ +E+++ +G +E++L+++ +E L +A ++ ++TGD ++TA + +
Sbjct: 677 ---ETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVARKSGM 733
Query: 694 FQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKAWTEHQEYGLI 753
+ +++ + E + + L+E +K +++ + + + ++
Sbjct: 734 VSESQKVILIEAN--ETTGSSSASISWTLVEEKKHIMYGNQDNYINIRDEVSDKGR---- 787
Query: 754 IDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPI 813
+GS + S S ++ S+ +I + T + RM+P QK+ +V + L
Sbjct: 788 -EGSYHFALTGKSFHVISQHFSSLLPKILINGT--IFARMSPGQKSSLVEEFQKL--DYF 842
Query: 814 TLSIGDGANDVSMILESHVGIGIKGKEGRQAA--RNSDYSVPKFKHLKK-----LLLAHG 866
GDGAND + +HVGI + +E A+ + ++ HL K L+ +
Sbjct: 843 VGMCGDGANDCGALKMAHVGISLSEQEASVASPFTSKTPNIECVPHLIKEGRAALVTSFC 902
Query: 867 HLYYVRIAHLVQY-----FFYKNLCFILPQFLYQ-----FFCGFSQQ---------PLYD 907
Y+ + ++QY +++ QFL+Q G + P
Sbjct: 903 MFKYMALYSMIQYVGVLLLYWETNSLSNYQFLFQDLAITTLIGVTMNLNGAYPKLVPFRP 962
Query: 908 AAYL--------TMYNICFT-SLPILAYSLLE---------------QHINIDTLTSDPR 943
A L ++NI + ++ I + L++ Q+ +I LT P
Sbjct: 963 AGRLISPPLLLSVIFNILLSLAMHIAGFILVQRQPWYSVEIHSACTVQNESISELTMSPT 1022
Query: 944 LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFFGTYFLFQTASLEENGKVYGNWTFGTIVF 1003
K+ N+ TF + TV+F GT A + GK + T+ +F
Sbjct: 1023 APEKMESNS----------TFTSFENTTVWFLGTINCITVALVFSKGKPFRQPTYTNYIF 1072
Query: 1004 TVLVFTVTLKLAL 1016
VLV + L + L
Sbjct: 1073 -VLVLIIQLGVCL 1084
>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo
sapiens]
Length = 1198
Score = 80.1 bits (196), Expect = 1e-14
Identities = 135/659 (20%), Positives = 243/659 (36%), Gaps = 132/659 (20%)
Query: 96 LPLFFVITVTAIKQGYEDWLRHRA----DNEVNKSTVYIIENAKRVRK-ESEKIKVGDVV 150
L + V+ VTA + DW + + + + + + + A +V + +I VGD+
Sbjct: 159 LSVICVVLVTA----FNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214
Query: 151 EVQADETFPCDLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAESID---- 206
+V+ + P D + + + +SL GES+ +D + L ++
Sbjct: 215 QVKYGDLLPADGLFIQG----NDLKIDESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGR 270
Query: 207 TLRAAIECEQPQPDLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVY 266
L A+ ++ +G G E K K + G A
Sbjct: 271 MLVTAVGVNSQTGIIFTLLGA---------------GGEEEEKKDKKAKQQD---GAAAM 312
Query: 267 TGMETKMALNYQGKSQKRSAV---EKSINAFLIVYLFILLTKAA--------VCTTLKYV 315
K A +K++++ EKS+ + L + + KA + L +
Sbjct: 313 EMQPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFT 372
Query: 316 WQSTPYNDEPWYNQKTQKERETLKVLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSF 375
+ N +PW + T ++ + V F FII V++ V + +
Sbjct: 373 VDTFVVNKKPWLPECTPV-------------YVQYFVKF-FIIGVTVLVVAVPEGLPLAV 418
Query: 376 FISWDKDFYDEEINEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYK 435
IS + + + LV D E +G + +DKTGTLT N M ++ + YK
Sbjct: 419 TISLAYSV-KKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYK 477
Query: 436 GVTQEVDGLSQTDGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELT 493
+ ++ EL + A+ + +T +I + +GA
Sbjct: 478 EIPDP--------------SSINTKTMELLINAIAINSAYTTKILPPEK-EGAL------ 516
Query: 494 YISSSPDEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVI 553
P ++ GF L + Y E R ++ E +L F++VR+ MS +
Sbjct: 517 -----PRQVGNKTECGLLGFV-LDLKQDY---EPVRSQMPEEKLYKVYTFNSVRKSMSTV 567
Query: 554 VKTQEGDILLFCKGADSAVF------------PRV--QNHEIELTKVHVERNAMDGYRTL 599
+K + ++ KGA V PRV E+ K +E A DG RT+
Sbjct: 568 IKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTI 627
Query: 600 CVAFKEI--APD-DYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQ 656
CVA+++ +P+ D++ N DI + I +ED ++
Sbjct: 628 CVAYRDFPSSPEPDWDNEN----------------------DILNELTCICVVGIEDPVR 665
Query: 657 DQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
+ E I AG+ V ++TGD + TA++ C + + L L K R E
Sbjct: 666 PEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNE 724
>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
sapiens]
Length = 1176
Score = 79.0 bits (193), Expect = 2e-14
Identities = 80/342 (23%), Positives = 131/342 (38%), Gaps = 60/342 (17%)
Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
+ + LV D E +G + +DKTGTLT N M ++ I+ YK V +
Sbjct: 451 MKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP------- 503
Query: 448 DGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKG 507
+ + N L L +V + + L + E AL+
Sbjct: 504 -------EAIPPN----ILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLG- 551
Query: 508 AKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKG 567
L + Y V N EI E L F++VR+ MS ++K +G +F KG
Sbjct: 552 ------LLLDLKRDYQDVRN---EIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKG 602
Query: 568 ADSAVFPRV-----QNHEI---------ELTKVHVERNAMDGYRTLCVAFKEIAPDDYER 613
A + + N E ++ K +E A +G RT+C+AF++ + E
Sbjct: 603 ASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPE- 661
Query: 614 INRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKV 673
D E +DI T + I +ED ++ + + I+ AG+ V
Sbjct: 662 ----------PEWDNE-------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 674 WVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
++TGD + TA++ C + + L L K R E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNE 746
>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
sapiens]
Length = 1220
Score = 79.0 bits (193), Expect = 2e-14
Identities = 80/342 (23%), Positives = 131/342 (38%), Gaps = 60/342 (17%)
Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
+ + LV D E +G + +DKTGTLT N M ++ I+ YK V +
Sbjct: 451 MKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEP------- 503
Query: 448 DGTLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKG 507
+ + N L L +V + + L + E AL+
Sbjct: 504 -------EAIPPN----ILSYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLG- 551
Query: 508 AKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKG 567
L + Y V N EI E L F++VR+ MS ++K +G +F KG
Sbjct: 552 ------LLLDLKRDYQDVRN---EIPEEALYKVYTFNSVRKSMSTVLKNSDGSYRIFSKG 602
Query: 568 ADSAVFPRV-----QNHEI---------ELTKVHVERNAMDGYRTLCVAFKEIAPDDYER 613
A + + N E ++ K +E A +G RT+C+AF++ + E
Sbjct: 603 ASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPE- 661
Query: 614 INRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKV 673
D E +DI T + I +ED ++ + + I+ AG+ V
Sbjct: 662 ----------PEWDNE-------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITV 704
Query: 674 WVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
++TGD + TA++ C + + L L K R E
Sbjct: 705 RMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNE 746
>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
Length = 1243
Score = 77.8 bits (190), Expect = 5e-14
Identities = 80/347 (23%), Positives = 135/347 (38%), Gaps = 71/347 (20%)
Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
+ + LV D E +G + +DKTGTLT N M ++ + YK +
Sbjct: 475 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDP------- 527
Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
++ EL + A+ + +T +I + +GA P ++
Sbjct: 528 -------SSINTKTMELLINAIAINSAYTTKILPPEK-EGAL-----------PRQVGNK 568
Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
GF L + Y E R ++ E +L F++VR+ MS ++K + ++
Sbjct: 569 TECGLLGFV-LDLKQDY---EPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDESFRMYS 624
Query: 566 KGADSAVF------------PRV--QNHEIELTKVHVERNAMDGYRTLCVAFKEI--APD 609
KGA V PRV E+ K +E A DG RT+CVA+++ +P+
Sbjct: 625 KGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPE 684
Query: 610 -DYERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHA 668
D++ N DI + I +ED ++ + E I
Sbjct: 685 PDWDNEN----------------------DILNELTCICVVGIEDPVRPEVPEAIRKCQR 722
Query: 669 AGLKVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
AG+ V ++TGD + TA++ C + + L L K R E
Sbjct: 723 AGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNE 769
>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
sapiens]
Length = 1220
Score = 74.7 bits (182), Expect = 5e-13
Identities = 76/344 (22%), Positives = 135/344 (39%), Gaps = 65/344 (18%)
Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
+ + LV D E +G + +DKTGTLT N M ++ + YK E+ S
Sbjct: 449 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK----EIPAPSAL 504
Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
+ +L + A+ + +T +I + +GA P ++
Sbjct: 505 TPKIL----------DLLVHAISINSAYTTKILPPEK-EGAL-----------PRQVGNK 542
Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
GF R+ + R++I E +L F++VR+ MS +++ +G LF
Sbjct: 543 TECALLGFVLDLKRD----FQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFS 598
Query: 566 KGADSAVFPRVQN--------------HEIELTKVHVERNAMDGYRTLCVAFKEIAPDDY 611
KGA + + N ++ + +E A DG RT+C+A+++ +
Sbjct: 599 KGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE 658
Query: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
D + + E V D + I +ED ++ + E I AG+
Sbjct: 659 P--------------DWDNENEVVGD-----LTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699
Query: 672 KVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
V ++TGD + TA++ C + Q + L L K R E
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743
>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
sapiens]
Length = 1173
Score = 74.7 bits (182), Expect = 5e-13
Identities = 76/344 (22%), Positives = 135/344 (39%), Gaps = 65/344 (18%)
Query: 388 INEGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQT 447
+ + LV D E +G + +DKTGTLT N M ++ + YK E+ S
Sbjct: 449 MKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYK----EIPAPSAL 504
Query: 448 DGTLTYFDKVDKNREELFLRALCL--CHTVEIKTNDAVDGATESAELTYISSSPDEIALV 505
+ +L + A+ + +T +I + +GA P ++
Sbjct: 505 TPKIL----------DLLVHAISINSAYTTKILPPEK-EGAL-----------PRQVGNK 542
Query: 506 KGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFC 565
GF R+ + R++I E +L F++VR+ MS +++ +G LF
Sbjct: 543 TECALLGFVLDLKRD----FQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMPDGGFRLFS 598
Query: 566 KGADSAVFPRVQN--------------HEIELTKVHVERNAMDGYRTLCVAFKEIAPDDY 611
KGA + + N ++ + +E A DG RT+C+A+++ +
Sbjct: 599 KGASEILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQE 658
Query: 612 ERINRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGL 671
D + + E V D + I +ED ++ + E I AG+
Sbjct: 659 P--------------DWDNENEVVGD-----LTCIAVVGIEDPVRPEVPEAIRKCQRAGI 699
Query: 672 KVWVLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKE 715
V ++TGD + TA++ C + Q + L L K R E
Sbjct: 700 TVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNE 743
>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
Length = 1039
Score = 67.4 bits (163), Expect = 7e-11
Identities = 127/601 (21%), Positives = 219/601 (36%), Gaps = 97/601 (16%)
Query: 390 EGALVNTSDLNEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKGVTQEVDGLSQTDG 449
+ LV + E LG + +DKTGTLT+N M D + T E D
Sbjct: 369 KNCLVKNLEAVETLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSE-------DH 421
Query: 450 TLTYFDKVDKNREELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSPDEIALVKGAK 509
+ FD+ + L + + LC+ E K + A + E AL+K
Sbjct: 422 SNQVFDQSSRTWASLS-KIITLCNRAEFKPGQENVPIMKKA----VIGDASETALLK--- 473
Query: 510 RYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCKGAD 569
+ LG+ M + + +++ E T F M L+ KGA
Sbjct: 474 -FSEVILGD---VMEIRKRNRKVAEIPFNSTNKFQLSIHEMD---DPHGKRFLMVMKGAP 526
Query: 570 SAVFPRVQNHEIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDRE 629
+ + I + ++++ + T A+ E+ + +++ +
Sbjct: 527 ERILEKCSTIMINGEEHPLDKSTAKTFHT---AYMELGG-----LGERVLGFCHLYLPAD 578
Query: 630 EKMEKVFDDIE------TNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMET 683
E E DI+ +N+ +G ++ D + + + +AG+KV ++TGD T
Sbjct: 579 EFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVIMVTGDHPIT 638
Query: 684 AKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSFKKA 743
AK+ + + N+E +E D H L I + + R K A
Sbjct: 639 AKAIAKSVGIISANSETVE-------------DIAHRLNIAVEQV-------NKRDAKAA 678
Query: 744 WTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVR 803
++ G L + + D NY+ I R +P QK IV
Sbjct: 679 ---------VVTGMELKDMSSEQLDEILANYQEIVF-----------ARTSPQQKLIIVE 718
Query: 804 MVKNLKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLL- 862
+ + + GDG ND + ++ +GI + G G AA+N+ V + ++
Sbjct: 719 GCQ--RQDAVVAVTGDGVNDSPALKKADIGIAM-GIAGSDAAKNAADMVLLDDNFASIVT 775
Query: 863 -LAHGHLYYVRIAHLVQYFFYKNLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSL 921
+ G L + + + Y KN+ + P FL G PL ++ T +
Sbjct: 776 GVEEGRLIFDNLKKTIAYSLTKNIAELCP-FLIYIIVGL---PLPIGTITILFIDLGTDI 831
Query: 922 ---PILAYSLLE--------QHINIDTLTSDP-RLYMKISGNAMLQLGPFLYWTFLAAFE 969
LAY E +H N D L + P +Y + M LG FL + + A E
Sbjct: 832 IPSIALAYEKAESDIMNRKPRHKNKDRLVNQPLAVYSYLHIGLMQALGAFLVYFTVYAQE 891
Query: 970 G 970
G
Sbjct: 892 G 892
Score = 42.0 bits (97), Expect = 0.003
Identities = 35/121 (28%), Positives = 57/121 (47%), Gaps = 9/121 (7%)
Query: 70 IANFYFLIIFLVQVTVDTPTS--PVTSGLPLFFVITVTAIKQGYEDWLRHRADNEVNK-- 125
+ F I + +Q + D S V G L V+ +T I Y++ + NK
Sbjct: 121 VGAFLCWIAYGIQYSSDKSASLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMI 180
Query: 126 -STVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSSCTTDGTCYVTTASLDGE 184
+I ++++ SE++ VGD+VEV+ + P D+ +LSS C V +SL GE
Sbjct: 181 PQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQIPADIRVLSS----QGCRVDNSSLTGE 236
Query: 185 S 185
S
Sbjct: 237 S 237
>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
sapiens]
Length = 1029
Score = 67.0 bits (162), Expect = 1e-10
Identities = 166/828 (20%), Positives = 297/828 (35%), Gaps = 210/828 (25%)
Query: 56 WNFLPKNLFEQFRRIANFYFLIIFLV-QVTVDTPTSPVTSGLPLFFVITVTAIKQGYEDW 114
W K LF F + ++ F+ + + P L L V++V I G +
Sbjct: 97 WVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCFSY 156
Query: 115 LRHRADNEVNKS-------TVYIIENAKRVRKESEKIKVGDVVEVQADETFPCDLILLSS 167
+ +++ +S +I ++++ +++ +GD+VE++ + P DL L+S+
Sbjct: 157 YQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLISA 216
Query: 168 CTTDGTCYVTTASLDGESNCK------THYAVRDTIALCTAESIDTLRAAIECEQPQPDL 221
C V +SL GES + TH +T +C +
Sbjct: 217 ----QGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFST----------------- 255
Query: 222 YKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQGKS 281
N + + + G ++ + A+L + G+AV G++
Sbjct: 256 -------NCVEGTARGIVIATGDSTVMGRIASLTS-----GLAV-------------GQT 290
Query: 282 QKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLKVL 341
+ +E I+ +V +F+ +T A+ L Y W
Sbjct: 291 PIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAII-------------------- 330
Query: 342 KMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDLNE 401
FL +++ N +P + TV + L + ++ + LV + E
Sbjct: 331 -----FLIGIIVAN--VPEGLLATVTVCLTLTAKRMA----------RKNCLVKNLEAVE 373
Query: 402 ELGQVDYVFTDKTGTLTENSMEFIECCIDGHKYKG-VTQEVDGLSQTDGTLTYFDKVDKN 460
LG + +DKTGTLT+N M D Y+ T+E G + T + T+F
Sbjct: 374 TLGSTSTICSDKTGTLTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWF------ 427
Query: 461 REELFLRALCLCHTVEIKTNDAV---------DGATESAELTYISSSPDEIALV--KGAK 509
+ R LC+ + K N + A+ESA L +I S +A + K K
Sbjct: 428 ---MLARIAGLCNRADFKANQEILPIAKRATTGDASESALLKFIEQSYSSVAEMREKNPK 484
Query: 510 RYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEGDILLFCK--- 566
F + N Y + R++ + +L ++K IL FC
Sbjct: 485 VAEIPF-NSTNKYQMSIHLREDSSQTHVL--------------MMKGAPERILEFCSTFL 529
Query: 567 ------GADSAVFPRVQNHEIELTKVHVERNAMDGYRTLCVAFKEIAPDDYERINRQLIE 620
+ + QN +EL + ER + L +F + P + + IN +
Sbjct: 530 LNGQEYSMNDEMKEAFQNAYLELGGLG-ERVLGFCFLNLPSSFSKGFPFNTDEINFPM-- 586
Query: 621 AKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDK 680
N+ +G ++ D + + + +AG+KV ++TGD
Sbjct: 587 --------------------DNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDH 626
Query: 681 METAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKKLLHEFPKSTRSF 740
TAK+ + TE E E +L K S
Sbjct: 627 PITAKAIAKGVGIISEGTETAE---------------------EVAARLKIPISKVDASA 665
Query: 741 KKAWTEHQEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQ 800
KA +++ G+ L I + D N+ I + R +P QK
Sbjct: 666 AKA--------IVVHGAELKDIQSKQLDQILQNHPEI-----------VFARTSPQQKLI 706
Query: 801 IVRMVKNLKGSPITLSIGDGANDVSMILESHVGI--GIKGKE-GRQAA 845
IV + L G+ + ++ GDG ND + ++ +GI GI G + +QAA
Sbjct: 707 IVEGCQRL-GAVVAVT-GDGVNDSPALKKADIGIAMGISGSDVSKQAA 752
>gi|148839292 ATPase type 13A3 [Homo sapiens]
Length = 1226
Score = 63.5 bits (153), Expect = 1e-09
Identities = 77/338 (22%), Positives = 138/338 (40%), Gaps = 57/338 (16%)
Query: 530 KEIEEYELLHTLNFDAVRR--------RMSVIVKTQEGDILL--FCKGADSAVFPRVQNH 579
+E+E +EL T VR+ RMSV+ + GD + + KGA A+ +
Sbjct: 607 QEMELFELPATYEIGIVRQFPFSSALQRMSVVARVL-GDRKMDAYMKGAPEAIAGLCKPE 665
Query: 580 EIELTKVHV-ERNAMDGYRTLCVAFKEIAPDDYERINRQLIEAKMALQDREEKMEKVFDD 638
+ + +V E G+R + +A +++ E+K+ K++ + D
Sbjct: 666 TVPVDFQNVLEDFTKQGFRVIALAHRKL-------------ESKLTWH----KVQNISRD 708
Query: 639 -IETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVWVLTGDKMETAKSTCYACRLFQTN 697
IE NM+ +G +++KL+ + +E LH A ++ ++TGD M TA S C +
Sbjct: 709 AIENNMDFMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQ 768
Query: 698 TELLELTTKTIEESERKEDRLHELLIEYRKKLL----------HEFPKSTRSFKKAWTEH 747
+++ E K+ ++ ++ Y L P +
Sbjct: 769 DKVI-----IAEALPPKDGKVAKINWHYADSLTQCSHPSAIDPEAIPVKLVHDSLEDLQM 823
Query: 748 QEYGLIIDGSTLSLILNSSQDSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKN 807
Y ++G + S+IL QD L + + RMAP QK Q++ ++N
Sbjct: 824 TRYHFAMNGKSFSVILEHFQD----------LVPKLMLHGTVFARMAPDQKTQLIEALQN 873
Query: 808 LKGSPITLSIGDGANDVSMILESHVGIGIKGKEGRQAA 845
+ GDGAND + +H GI + E A+
Sbjct: 874 V--DYFVGMCGDGANDCGALKRAHGGISLSELEASVAS 909
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,282,633
Number of Sequences: 37866
Number of extensions: 1577438
Number of successful extensions: 4651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 4291
Number of HSP's gapped (non-prelim): 248
length of query: 1132
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1019
effective length of database: 13,968,660
effective search space: 14234064540
effective search space used: 14234064540
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.