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Search of human proteins with 40255119
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
(740 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40255119 RAS and EF-hand domain containing [Homo sapiens] 1462 0.0
gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo s... 245 9e-65
gi|16933567 mel transforming oncogene [Homo sapiens] 159 7e-39
gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens] 157 4e-38
gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo sa... 149 9e-36
gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo sa... 147 3e-35
gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens] 147 3e-35
gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo sap... 145 2e-34
gi|46361978 RAB26, member RAS oncogene family [Homo sapiens] 143 7e-34
gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens] 142 9e-34
gi|4506363 RAB13, member RAS oncogene family [Homo sapiens] 140 4e-33
gi|50234889 RAB43 protein [Homo sapiens] 140 6e-33
gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene fa... 139 1e-32
gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens] 139 1e-32
gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens] 139 1e-32
gi|21361418 RAB30, member RAS oncogene family [Homo sapiens] 137 5e-32
gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens] 132 1e-30
gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens] 131 2e-30
gi|5803135 RAB35, member RAS oncogene family [Homo sapiens] 130 3e-30
gi|106507164 RAB12, member RAS oncogene family [Homo sapiens] 130 3e-30
gi|21361884 RAB2B protein isoform 1 [Homo sapiens] 130 4e-30
gi|4758984 Ras-related protein Rab-11A [Homo sapiens] 130 4e-30
gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens] 129 7e-30
gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens] 129 1e-29
gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens] 129 1e-29
gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens] 126 8e-29
gi|34485711 Ras-related protein Rab-27A [Homo sapiens] 125 1e-28
gi|34485709 Ras-related protein Rab-27A [Homo sapiens] 125 1e-28
gi|34485706 Ras-related protein Rab-27A [Homo sapiens] 125 1e-28
gi|19923264 Ras-related protein Rab-27A [Homo sapiens] 125 1e-28
>gi|40255119 RAS and EF-hand domain containing [Homo sapiens]
Length = 740
Score = 1462 bits (3784), Expect = 0.0
Identities = 740/740 (100%), Positives = 740/740 (100%)
Query: 1 MEADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG 60
MEADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG
Sbjct: 1 MEADGDGEELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDG 60
Query: 61 AITFQEFARGFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDEGDEDAAAALATSCG 120
AITFQEFARGFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDEGDEDAAAALATSCG
Sbjct: 61 AITFQEFARGFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDEGDEDAAAALATSCG 120
Query: 121 PASPGRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQ 180
PASPGRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQ
Sbjct: 121 PASPGRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQ 180
Query: 181 STEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYE 240
STEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYE
Sbjct: 181 STEMENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYE 240
Query: 241 TEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFL 300
TEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFL
Sbjct: 241 TEVGDLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFL 300
Query: 301 QSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSAL 360
QSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSAL
Sbjct: 301 QSELDALKSDYADQSLNTERDLEIIRAYTEDRNSLERQIEILQTANRKLHDSNDGLRSAL 360
Query: 361 ENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDP 420
ENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDP
Sbjct: 361 ENSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDP 420
Query: 421 LQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDV 480
LQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDV
Sbjct: 421 LQRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDV 480
Query: 481 PDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQK 540
PDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQK
Sbjct: 481 PDIRDEETFGLEDVASVLDWKPQGSVSEGSIVSSSRKPISALSPQTDLVDDNAKSFSSQK 540
Query: 541 AYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQ 600
AYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQ
Sbjct: 541 AYKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQ 600
Query: 601 ERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRD 660
ERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRD
Sbjct: 601 ERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRD 660
Query: 661 TAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSI 720
TAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSI
Sbjct: 661 TAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSI 720
Query: 721 TNLTGTNSKKSPQMKNCCNG 740
TNLTGTNSKKSPQMKNCCNG
Sbjct: 721 TNLTGTNSKKSPQMKNCCNG 740
>gi|222418791 EF-hand calcium binding domain 4B isoform a [Homo
sapiens]
Length = 731
Score = 245 bits (626), Expect = 9e-65
Identities = 206/745 (27%), Positives = 352/745 (47%), Gaps = 82/745 (11%)
Query: 10 LARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAEAVFQRLDADRDGAITFQEFAR 69
L + + F CDA G + R++ + L EL + + E VF LDAD +G +T QEF
Sbjct: 52 LRKAQEFFQTCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTT 111
Query: 70 GFLGSLRGGRRRDWGPLDPAPAVSEAGPETHDSEEDE-----GDEDAAAALATSCGPASP 124
GF P+ +AG + E++ GDED G
Sbjct: 112 GFSHFFFSQNN---------PSQEDAGEQVAQRHEEKVYLSRGDEDLG-----DMGEDEE 157
Query: 125 GRAWQDFQARLGDEAKFIPREEQVSTLYQNINLVEPRLIQPYEHVIKNFIREIRLQSTEM 184
+ ++ RLG + K + E V L+ + EP L+ +E + I +++ E
Sbjct: 158 AQ-FRMLMDRLGAQ-KVLEDESDVKQLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEK 215
Query: 185 ENLAIAVKRAQDKAAMQLSELEEEMDQRIQAAEHKTRKDEKRKAEEALSDLRRQYETEVG 244
L A+KR ++ L EEM+Q+I++ + + + + + +L ++ +
Sbjct: 216 NELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQ 275
Query: 245 DLQVTIKKLRKLEEQSKRVSQKEDVAALKKQIYDLSMENQKVKKDLLEAQTNIAFLQSEL 304
+L+ +K ++LE Q + D K + L + NQ++ ++L + Q +L
Sbjct: 276 ELEQLTQKQKRLEGQCTALHH--DKHETKAENTKLKLTNQELARELERTSWELQDAQQQL 333
Query: 305 DALKSDYADQSLNTERDLEIIR---AYTEDRNSLERQIEILQTANRKLHDSNDGLRSALE 361
++L+ + L+ E+++E+ R + ++ L +Q++ L+ N+ L D D
Sbjct: 334 ESLQQEAC--KLHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDERD------- 384
Query: 362 NSYSKFNRSLHINNISPGNTISRSSPKFIGHSPQPLGYDRSSRSSYVDEDCDSLALCDPL 421
+ K N++ N + + + S IG G RS S +E+ +
Sbjct: 385 ICFQK-NKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQ--SEEEEEVFGIP----- 436
Query: 422 QRTNCEVDSLPESCFDSGLSTLRDPNEYDSEVEYKHQRGFQRSHGVQESFGGDASDTDVP 481
+R++ + P T +P + + R +R V+E +P
Sbjct: 437 RRSSLGLSGYP--------LTEEEPGTGEPGPGGPYPRPLRRIISVEED--------PLP 480
Query: 482 DIRDEETFGLEDVASVLDWKPQGSVS--EGSIVSSSRKPISALSPQTDLVDDNA--KSFS 537
+ D G E S + + S +G I + ++ SP+ V A K S
Sbjct: 481 QLLDG---GFEQPLSKCSEEEEVSDQGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEES 537
Query: 538 SQKA----YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQ 593
S A +KIV G++AVGK+SFL R C++ F ++AT+G+D+++KTL VD + LQ
Sbjct: 538 SPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQ 597
Query: 594 LWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVG 653
LWDTAGQER+R I + +FRKADGV+++YD+T ++SFL++R W+ +E+A + VP++L+G
Sbjct: 598 LWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLG 657
Query: 654 NKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTD 713
NK D E ++ VP GE+LA +F E SA G N E++LHLAR +K++
Sbjct: 658 NKLD------NEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQ-- 709
Query: 714 KDDSRSITNLTGTNSKKSPQMKNCC 738
+D R T G +KK K+CC
Sbjct: 710 EDTVREDTIQVGHPAKK----KSCC 730
>gi|16933567 mel transforming oncogene [Homo sapiens]
Length = 207
Score = 159 bits (403), Expect = 7e-39
Identities = 78/173 (45%), Positives = 114/173 (65%), Gaps = 6/173 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGK+ L R ++ F +T+G+DF+++T+ +DG+R LQ+WDTAGQE
Sbjct: 9 FKLLLIGDSGVGKTCVLFRFSEDAFNSTFISTIGIDFKIRTIELDGKRIKLQIWDTAGQE 68
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFR+I +Y+R A G++L+YD+T EKSF NIR W+ IE+ A V M++GNK D+ D
Sbjct: 69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIRNWIRNIEEHASADVEKMILGNKCDVNDK 128
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDK 714
++ GEKLA+ YG F ETSAK N+ A LAR++K + DK
Sbjct: 129 RQVSKER------GEKLALDYGIKFMETSAKANINVENAFFTLARDIKAKMDK 175
>gi|7706563 RAB8B, member RAS oncogene family [Homo sapiens]
Length = 207
Score = 157 bits (396), Expect = 4e-38
Identities = 81/197 (41%), Positives = 125/197 (63%), Gaps = 13/197 (6%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGK+ L R ++ F +T+G+DF+++T+ +DG++ LQ+WDTAGQE
Sbjct: 9 FKLLLIGDSGVGKTCLLFRFSEDAFNTTFISTIGIDFKIRTIELDGKKIKLQIWDTAGQE 68
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFR+I +Y+R A G++L+YD+T EKSF NI+ W+ IE+ A V M++GNK D+ D
Sbjct: 69 RFRTITTAYYRGAMGIMLVYDITNEKSFDNIKNWIRNIEEHASSDVERMILGNKCDMNDK 128
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDK--DDSRS 719
++ GEKLA+ YG F ETSAK +N+ EA LAR++ + ++ +DS S
Sbjct: 129 RQVSKER------GEKLAIDYGIKFLETSAKSSANVEEAFFTLARDIMTKLNRKMNDSNS 182
Query: 720 I-----TNLTGTNSKKS 731
+T SKK+
Sbjct: 183 AGAGGPVKITENRSKKT 199
>gi|28376635 RAB37, member RAS oncogene family isoform 3 [Homo
sapiens]
Length = 216
Score = 149 bits (376), Expect = 9e-36
Identities = 86/208 (41%), Positives = 123/208 (59%), Gaps = 14/208 (6%)
Query: 536 FSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRE-NISATLGVDFQMKTLIVDGERTVLQL 594
F+ +K +L GD+ VGK+S L++ + +F + SAT+G+ F K + VDG R LQ+
Sbjct: 17 FNDHVLHKTILVGDSGVGKTSLLVQFDQGKFIPGSFSATVGIGFTNKVVTVDGVRVKLQI 76
Query: 595 WDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGN 654
WDTAGQERFRS+ +Y+R A +LLLYD+T + SF NIR W+ I + A V IML+GN
Sbjct: 77 WDTAGQERFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGN 136
Query: 655 KADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTD- 713
KAD+ ++ + GE LA YG F ETSAK G N+ A L +A+E+K R
Sbjct: 137 KADM------SSERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAGH 190
Query: 714 --KDDSRSITNLTGTNSKKSPQMKNCCN 739
+ S I + + K+S +CC+
Sbjct: 191 QADEPSFQIRDYVESQKKRS----SCCS 214
>gi|54859685 RAB37, member RAS oncogene family isoform 2 [Homo
sapiens]
Length = 223
Score = 147 bits (371), Expect = 3e-35
Identities = 85/201 (42%), Positives = 118/201 (58%), Gaps = 14/201 (6%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFREN-ISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
K++L GD VGK+ FL++ F AT+G+DF+ K + VDG R LQ+WDTAGQE
Sbjct: 31 KVMLLGDTGVGKTCFLIQFKDGAFLSGTFIATVGIDFRNKVVTVDGVRVKLQIWDTAGQE 90
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFRS+ +Y+R A +LLLYD+T + SF NIR W+ I + A V IML+GNKAD+
Sbjct: 91 RFRSVTHAYYRDAQALLLLYDITNKSSFDNIRAWLTEIHEYAQRDVVIMLLGNKADM--- 147
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTD---KDDSR 718
++ + GE LA YG F ETSAK G N+ A L +A+E+K R + S
Sbjct: 148 ---SSERVIRSEDGETLAREYGVPFLETSAKTGMNVELAFLAIAKELKYRAGHQADEPSF 204
Query: 719 SITNLTGTNSKKSPQMKNCCN 739
I + + K+S +CC+
Sbjct: 205 QIRDYVESQKKRS----SCCS 221
>gi|13569962 RAB1B, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 147 bits (371), Expect = 3e-35
Identities = 71/170 (41%), Positives = 116/170 (68%), Gaps = 6/170 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGKS L+R + + E+ +T+GVDF+++T+ +DG+ LQ+WDTAGQE
Sbjct: 9 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 68
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFR+I SY+R A G++++YDVT ++S+ N+++W+ I+ A E V +LVGNK+D+
Sbjct: 69 RFRTITSSYYRGAHGIIVVYDVTDQESYANVKQWLQEIDRYASENVNKLLVGNKSDLTT- 127
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
+K V ++ A + G F ETSAK+ +N+ +A + +A E+KKR
Sbjct: 128 -----KKVVDNTTAKEFADSLGIPFLETSAKNATNVEQAFMTMAAEIKKR 172
>gi|4758988 RAB1A, member RAS oncogene family isoform 1 [Homo
sapiens]
Length = 205
Score = 145 bits (365), Expect = 2e-34
Identities = 71/170 (41%), Positives = 115/170 (67%), Gaps = 6/170 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGKS L+R + + E+ +T+GVDF+++T+ +DG+ LQ+WDTAGQE
Sbjct: 12 FKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQE 71
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFR+I SY+R A G++++YDVT ++SF N+++W+ I+ A E V +LVGNK D+
Sbjct: 72 RFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTT- 130
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
+K V ++ A + G F ETSAK+ +N+ ++ + +A E+KKR
Sbjct: 131 -----KKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKR 175
>gi|46361978 RAB26, member RAS oncogene family [Homo sapiens]
Length = 256
Score = 143 bits (360), Expect = 7e-34
Identities = 80/178 (44%), Positives = 111/178 (62%), Gaps = 7/178 (3%)
Query: 541 AYKIVLAGDAAVGKSSFLMRLCKNEFREN-ISATLGVDFQMKTLIVDGERTVLQLWDTAG 599
A+K++L GD+ VGK+ L+R F +T+G+DF+ K L VDG + LQ+WDTAG
Sbjct: 63 AFKVMLVGDSGVGKTCLLVRFKDGAFLAGTFISTVGIDFRNKVLDVDGVKVKLQMWDTAG 122
Query: 600 QERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIR 659
QERFRS+ +Y+R A +LLLYDVT + SF NI+ W+ I + A V +ML+GNK D
Sbjct: 123 QERFRSVTHAYYRDAHALLLLYDVTNKASFDNIQAWLTEIHEYAQHDVALMLLGNKVD-- 180
Query: 660 DTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDS 717
+ ++ V GEKLA YG F ETSAK G N+ A +A+E+K+R+ K S
Sbjct: 181 ----SAHERVVKREDGEKLAKEYGLPFMETSAKTGLNVDLAFTAIAKELKQRSMKAPS 234
>gi|33695095 ras-related GTP-binding protein RAB10 [Homo sapiens]
Length = 200
Score = 142 bits (359), Expect = 9e-34
Identities = 74/178 (41%), Positives = 114/178 (64%), Gaps = 6/178 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGK+ L R + F +T+G+DF++KT+ + G++ LQ+WDTAGQE
Sbjct: 10 FKLLLIGDSGVGKTCVLFRFSDDAFNTTFISTIGIDFKIKTVELQGKKIKLQIWDTAGQE 69
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RF +I SY+R A G++L+YD+T KSF NI +W+ I++ A+E V ML+GNK D+ D
Sbjct: 70 RFHTITTSYYRGAMGIMLVYDITNGKSFENISKWLRNIDEHANEDVERMLLGNKCDMDD- 128
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRS 719
++ VP G ++A +G F ETSAK NI +A L LA ++ ++T + S
Sbjct: 129 -----KRVVPKGKGGQIAREHGIRFFETSAKANINIEKAFLTLAEDILRKTPVKEPNS 181
>gi|4506363 RAB13, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 140 bits (353), Expect = 4e-33
Identities = 68/167 (40%), Positives = 111/167 (66%), Gaps = 6/167 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L GD+ VGK+ ++R ++ F +T+G+DF+++T+ ++G++ LQ+WDTAGQE
Sbjct: 9 FKLLLIGDSGVGKTCLIIRFAEDNFNNTYISTIGIDFKIRTVDIEGKKIKLQVWDTAGQE 68
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RF++I +Y+R A G++L+YD+T EKSF NI+ W+ I++ A V +L+GNK D+
Sbjct: 69 RFKTITTAYYRGAMGIILVYDITDEKSFENIQNWMKSIKENASAGVERLLLGNKCDM--- 125
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREV 708
E ++ V +KLA +G F ETSAK N+ EA LAR++
Sbjct: 126 ---EAKRKVQKEQADKLAREHGIRFFETSAKSSMNVDEAFSSLARDI 169
>gi|50234889 RAB43 protein [Homo sapiens]
Length = 212
Score = 140 bits (352), Expect = 6e-33
Identities = 76/174 (43%), Positives = 107/174 (61%), Gaps = 13/174 (7%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K+VL GDA+VGK+ + R F E +T+GVDF MKTL + G+R LQ+WDTAGQE
Sbjct: 19 FKLVLVGDASVGKTCVVQRFKTGAFSERQGSTIGVDFTMKTLEIQGKRVKLQIWDTAGQE 78
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKAD---I 658
RFR+I +SY+R A+G +L YD+T SFL++ W++ + A + +L+GNK+D +
Sbjct: 79 RFRTITQSYYRSANGAILAYDITKRSSFLSVPHWIEDVRKYAGSNIVQLLIGNKSDLSEL 138
Query: 659 RDTAATEGQKCVPGHFGEKLAMTYGALFC-ETSAKDGSNIVEAVLHLAREVKKR 711
R+ + E Q LA Y L ETSAKD SN+ EA L +A E+ R
Sbjct: 139 REVSLAEAQ---------SLAEHYDILCAIETSAKDSSNVEEAFLRVATELIMR 183
>gi|169204777 PREDICTED: similar to RAB13, member RAS oncogene
family [Homo sapiens]
Length = 327
Score = 139 bits (349), Expect = 1e-32
Identities = 73/197 (37%), Positives = 119/197 (60%), Gaps = 18/197 (9%)
Query: 512 VSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENIS 571
+ S P+SA++ D + +K++L GD+ VGK+ ++R ++ F
Sbjct: 115 IPSPAPPVSAMAKAYDHL------------FKLLLIGDSGVGKTCLIIRFAEDNFNNTYI 162
Query: 572 ATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLN 631
+T+G+DF+++T+ ++G++ LQ+WDTAGQERF++I +Y+R A G++L YD+T EKSF N
Sbjct: 163 STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFEN 222
Query: 632 IREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSA 691
I+ W+ I + A V +L+GNK D+ E ++ V +KLA +G F ETSA
Sbjct: 223 IQNWMKSIMENASAGVEHLLLGNKCDM------EAKRKVQKEQADKLAREHGIRFFETSA 276
Query: 692 KDGSNIVEAVLHLAREV 708
K N+ EA LAR++
Sbjct: 277 KSSMNVDEAFSSLARDI 293
>gi|169205558 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 139 bits (349), Expect = 1e-32
Identities = 73/197 (37%), Positives = 119/197 (60%), Gaps = 18/197 (9%)
Query: 512 VSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENIS 571
+ S P+SA++ D + +K++L GD+ VGK+ ++R ++ F
Sbjct: 115 IPSPAPPVSAMAKAYDHL------------FKLLLIGDSGVGKTCLIIRFAEDNFNNTYI 162
Query: 572 ATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLN 631
+T+G+DF+++T+ ++G++ LQ+WDTAGQERF++I +Y+R A G++L YD+T EKSF N
Sbjct: 163 STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFEN 222
Query: 632 IREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSA 691
I+ W+ I + A V +L+GNK D+ E ++ V +KLA +G F ETSA
Sbjct: 223 IQNWMKSIMENASAGVEHLLLGNKCDM------EAKRKVQKEQADKLAREHGIRFFETSA 276
Query: 692 KDGSNIVEAVLHLAREV 708
K N+ EA LAR++
Sbjct: 277 KSSMNVDEAFSSLARDI 293
>gi|169204174 PREDICTED: similar to hCG24991 [Homo sapiens]
Length = 327
Score = 139 bits (349), Expect = 1e-32
Identities = 73/197 (37%), Positives = 119/197 (60%), Gaps = 18/197 (9%)
Query: 512 VSSSRKPISALSPQTDLVDDNAKSFSSQKAYKIVLAGDAAVGKSSFLMRLCKNEFRENIS 571
+ S P+SA++ D + +K++L GD+ VGK+ ++R ++ F
Sbjct: 115 IPSPAPPVSAMAKAYDHL------------FKLLLIGDSGVGKTCLIIRFAEDNFNNTYI 162
Query: 572 ATLGVDFQMKTLIVDGERTVLQLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLN 631
+T+G+DF+++T+ ++G++ LQ+WDTAGQERF++I +Y+R A G++L YD+T EKSF N
Sbjct: 163 STIGIDFKIRTVDIEGKKIKLQVWDTAGQERFKTITTAYYRGAMGIILAYDITDEKSFEN 222
Query: 632 IREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSA 691
I+ W+ I + A V +L+GNK D+ E ++ V +KLA +G F ETSA
Sbjct: 223 IQNWMKSIMENASAGVEHLLLGNKCDM------EAKRKVQKEQADKLAREHGIRFFETSA 276
Query: 692 KDGSNIVEAVLHLAREV 708
K N+ EA LAR++
Sbjct: 277 KSSMNVDEAFSSLARDI 293
>gi|21361418 RAB30, member RAS oncogene family [Homo sapiens]
Length = 203
Score = 137 bits (344), Expect = 5e-32
Identities = 75/198 (37%), Positives = 111/198 (56%), Gaps = 6/198 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+KIVL G+A VGK+ + R + F AT+GVDF +KT+ ++GE+ LQ+WDTAGQE
Sbjct: 10 FKIVLIGNAGVGKTCLVRRFTQGLFPPGQGATIGVDFMIKTVEINGEKVKLQIWDTAGQE 69
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFRSI +SY+R A+ ++L YD+TCE+SF + EW+ IE A V +LVGNK D+ +
Sbjct: 70 RFRSITQSYYRSANALILTYDITCEESFRCLPEWLREIEQYASNKVITVLVGNKIDLAER 129
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT 721
Q+ E+ + + ETSAK+ N+ + L LA + ++ +
Sbjct: 130 REVSQQR------AEEFSEAQDMYYLETSAKESDNVEKLFLDLACRLISEARQNTLVNNV 183
Query: 722 NLTGTNSKKSPQMKNCCN 739
+ KS CCN
Sbjct: 184 SSPLPGEGKSISYLTCCN 201
>gi|4506365 RAB2A, member RAS oncogene family [Homo sapiens]
Length = 212
Score = 132 bits (332), Expect = 1e-30
Identities = 65/170 (38%), Positives = 105/170 (61%), Gaps = 6/170 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K ++ GD VGKS L++ F+ T+GV+F + + +DG++ LQ+WDTAGQE
Sbjct: 7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
FRSI +SY+R A G LL+YD+T +F ++ W++ ++ + IML+GNK+D+
Sbjct: 67 SFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDL--- 123
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
E ++ V GE A +G +F ETSAK SN+ EA ++ A+E+ ++
Sbjct: 124 ---ESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEK 170
>gi|190358517 RAB11B, member RAS oncogene family [Homo sapiens]
Length = 218
Score = 131 bits (330), Expect = 2e-30
Identities = 72/210 (34%), Positives = 112/210 (53%), Gaps = 19/210 (9%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K+VL GD+ VGKS+ L R +NEF +T+GV+F +++ VDG+ Q+WDTAGQE
Sbjct: 12 FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
R+R+I +Y+R A G LL+YD+ ++ N+ W+ + D A + IMLVGNK+D+R
Sbjct: 72 RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHL 131
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREV-----------KK 710
A VP A F ETSA D +N+ EA ++ E+ +
Sbjct: 132 RA------VPTDEARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRIVSQKQIADRA 185
Query: 711 RTDKDDSRSITNLT--GTNSKKSPQMKNCC 738
D+ ++ +++ T + P CC
Sbjct: 186 AHDESPGNNVVDISVPPTTDGQKPNKLQCC 215
>gi|5803135 RAB35, member RAS oncogene family [Homo sapiens]
Length = 201
Score = 130 bits (328), Expect = 3e-30
Identities = 75/204 (36%), Positives = 112/204 (54%), Gaps = 18/204 (8%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K+++ GD+ VGKSS L+R N F + T+GVDF+++T+ ++GE+ LQ+WDTAGQE
Sbjct: 9 FKLLIIGDSGVGKSSLLLRFADNTFSGSYITTIGVDFKIRTVEINGEKVKLQIWDTAGQE 68
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
RFR+I +Y+R GV+++YDVT +SF+N++ W+ I + I LVGNK D +
Sbjct: 69 RFRTITSTYYRGTHGVIVVYDVTSAESFVNVKRWLHEINQNCDDVCRI-LVGNKNDDPE- 126
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSN-------IVEAVLHLAREVKKRTDK 714
+K V K A G ETSAK+ N I E VL ++ + +
Sbjct: 127 -----RKVVETEDAYKFAGQMGIQLFETSAKENVNVEEMFNCITELVLRAKKDNLAKQQQ 181
Query: 715 DDSRSITNLTGTNSKKSPQMKNCC 738
+ LT K S + K CC
Sbjct: 182 QQQNDVVKLT----KNSKRKKRCC 201
>gi|106507164 RAB12, member RAS oncogene family [Homo sapiens]
Length = 244
Score = 130 bits (328), Expect = 3e-30
Identities = 69/178 (38%), Positives = 108/178 (60%), Gaps = 7/178 (3%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQER 602
++++ G VGK+S + R + F E +T+GVDF++KT+ + G++ LQ+WDTAGQER
Sbjct: 44 QVIIIGSRGVGKTSLMERFTDDTFCEACKSTVGVDFKIKTVELRGKKIRLQIWDTAGQER 103
Query: 603 FRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDTA 662
F SI +Y+R A G++L+YD+T +++F ++ +W+ MI+ A E ++LVGNK D
Sbjct: 104 FNSITSAYYRSAKGIILVYDITKKETFDDLPKWMKMIDKYASEDAELLLVGNKLD----- 158
Query: 663 ATEGQKCVPGHFGEKLAMTY-GALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRS 719
E + + GEK A G FCE SAKD N+ E L L ++ K+ D R+
Sbjct: 159 -CETDREITRQQGEKFAQQITGMRFCEASAKDNFNVDEIFLKLVDDILKKMPLDILRN 215
>gi|21361884 RAB2B protein isoform 1 [Homo sapiens]
Length = 216
Score = 130 bits (327), Expect = 4e-30
Identities = 64/170 (37%), Positives = 104/170 (61%), Gaps = 6/170 (3%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K ++ GD VGKS L++ F+ T+GV+F + + +DG++ LQ+WDTAGQE
Sbjct: 7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMVNIDGKQIKLQIWDTAGQE 66
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
FRSI +SY+R A G LL+YD+T ++F ++ W++ + + IML+GNK+D+
Sbjct: 67 SFRSITRSYYRGAAGALLVYDITRRETFNHLTSWLEDARQHSSSNMVIMLIGNKSDL--- 123
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
E ++ V GE A +G +F ETSAK N+ EA ++ A+E+ ++
Sbjct: 124 ---ESRRDVKREEGEAFAREHGLIFMETSAKTACNVEEAFINTAKEIYRK 170
>gi|4758984 Ras-related protein Rab-11A [Homo sapiens]
Length = 216
Score = 130 bits (327), Expect = 4e-30
Identities = 71/208 (34%), Positives = 110/208 (52%), Gaps = 17/208 (8%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K+VL GD+ VGKS+ L R +NEF +T+GV+F +++ VDG+ Q+WDTAGQE
Sbjct: 12 FKVVLIGDSGVGKSNLLSRFTRNEFNLESKSTIGVEFATRSIQVDGKTIKAQIWDTAGQE 71
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
R+R+I +Y+R A G LL+YD+ ++ N+ W+ + D A + IMLVGNK+D+R
Sbjct: 72 RYRAITSAYYRGAVGALLVYDIAKHLTYENVERWLKELRDHADSNIVIMLVGNKSDLRHL 131
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREV-----------KK 710
A VP A G F ETSA D +N+ A + E+ ++
Sbjct: 132 RA------VPTDEARAFAEKNGLSFIETSALDSTNVEAAFQTILTEIYRIVSQKQMSDRR 185
Query: 711 RTDKDDSRSITNLTGTNSKKSPQMKNCC 738
D S ++ + + ++ CC
Sbjct: 186 ENDMSPSNNVVPIHVPPTTENKPKVQCC 213
>gi|4506367 RAB3A, member RAS oncogene family [Homo sapiens]
Length = 220
Score = 129 bits (325), Expect = 7e-30
Identities = 68/195 (34%), Positives = 116/195 (59%), Gaps = 8/195 (4%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+KI++ G+++VGK+SFL R + F +T+G+DF++KT+ + +R LQ+WDTAGQE
Sbjct: 23 FKILIIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTIYRNDKRIKLQIWDTAGQE 82
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
R+R+I +Y+R A G +L+YD+T E+SF +++W I+ + + ++LVGNK D+ D
Sbjct: 83 RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVLLVGNKCDMED- 141
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT 721
++ V G +LA G F E SAKD N+ + L + ++ +S
Sbjct: 142 -----ERVVSSERGRQLADHLGFEFFEASAKDNINVKQTFERLVDVICEK--MSESLDTA 194
Query: 722 NLTGTNSKKSPQMKN 736
+ T +K+ PQ+ +
Sbjct: 195 DPAVTGAKQGPQLSD 209
>gi|5729997 RAB27B, member RAS oncogene family [Homo sapiens]
Length = 218
Score = 129 bits (324), Expect = 1e-29
Identities = 78/214 (36%), Positives = 122/214 (57%), Gaps = 24/214 (11%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGE----------RTVL 592
K++ GD+ VGK++FL R N+F T+G+DF+ K ++ + + + L
Sbjct: 11 KLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHL 70
Query: 593 QLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH-ETVPIML 651
QLWDTAGQERFRS+ ++FR A G LL++D+T ++SFLN+R W+ ++ A+ E I+L
Sbjct: 71 QLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVL 130
Query: 652 VGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
+GNKAD+ D Q+ V +LA YG + ETSA G N+ +AV L + KR
Sbjct: 131 IGNKADLPD------QREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKR 184
Query: 712 TDK--DDSRSITNLTGTNS-----KKSPQMKNCC 738
++ + ++ + G NS +K P+ K C
Sbjct: 185 MEQCVEKTQIPDTVNGGNSGNLDGEKPPEKKCIC 218
>gi|4759000 RAB3D, member RAS oncogene family [Homo sapiens]
Length = 219
Score = 129 bits (324), Expect = 1e-29
Identities = 69/203 (33%), Positives = 119/203 (58%), Gaps = 15/203 (7%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K++L G+++VGK+SFL R + F +T+G+DF++KT+ +R LQ+WDTAGQE
Sbjct: 23 FKLLLIGNSSVGKTSFLFRYADDSFTPAFVSTVGIDFKVKTVYRHDKRIKLQIWDTAGQE 82
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
R+R+I +Y+R A G LL+YD+ ++SF +++W I+ + + ++LVGNK D+ D
Sbjct: 83 RYRTITTAYYRGAMGFLLMYDIANQESFAAVQDWATQIKTYSWDNAQVILVGNKCDLED- 141
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT 721
++ VP G +LA G F E SAK+ N+ + L + ++ ++S +
Sbjct: 142 -----ERVVPAEDGRRLADDLGFEFFEASAKENINVKQVFERLVDVICEK--MNESLEPS 194
Query: 722 NLTGTNSK-------KSPQMKNC 737
+ +G+N K +PQ +C
Sbjct: 195 SSSGSNGKGPAVGDAPAPQPSSC 217
>gi|19923985 RAB3C, member RAS oncogene family [Homo sapiens]
Length = 227
Score = 126 bits (316), Expect = 8e-29
Identities = 70/194 (36%), Positives = 116/194 (59%), Gaps = 9/194 (4%)
Query: 542 YKIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVDGERTVLQLWDTAGQE 601
+K+++ G+++VGK+SFL R + F +T+G+DF++KT+ + +R LQ+WDTAGQE
Sbjct: 31 FKLLIIGNSSVGKTSFLFRYADDSFTSAFVSTVGIDFKVKTVFKNEKRIKLQIWDTAGQE 90
Query: 602 RFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAHETVPIMLVGNKADIRDT 661
R+R+I +Y+R A G +L+YD+T E+SF +++W I+ + + ++LVGNK D+ D
Sbjct: 91 RYRTITTAYYRGAMGFILMYDITNEESFNAVQDWSTQIKTYSWDNAQVILVGNKCDMEDE 150
Query: 662 AATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSIT 721
++ H GE+L G F ETSAKD N+ + R V DK T
Sbjct: 151 RVISTER--GQHLGEQL----GFEFFETSAKDNINVKQT---FERLVDIICDKMSESLET 201
Query: 722 NLTGTNSKKSPQMK 735
+ T +K++ ++K
Sbjct: 202 DPAITAAKQNTRLK 215
>gi|34485711 Ras-related protein Rab-27A [Homo sapiens]
Length = 221
Score = 125 bits (314), Expect = 1e-28
Identities = 70/183 (38%), Positives = 107/183 (58%), Gaps = 17/183 (9%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVD----------GERTVL 592
K + GD+ VGK+S L + +F T+G+DF+ K ++ G+R L
Sbjct: 11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70
Query: 593 QLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH-ETVPIML 651
QLWDTAGQERFRS+ ++FR A G LLL+D+T E+SFLN+R W+ ++ A+ E I+L
Sbjct: 71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVL 130
Query: 652 VGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
GNK+D+ D + ++ + LA YG + ETSA +G+NI +A+ L + KR
Sbjct: 131 CGNKSDLEDQRVVKEEEAI------ALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKR 184
Query: 712 TDK 714
++
Sbjct: 185 MER 187
>gi|34485709 Ras-related protein Rab-27A [Homo sapiens]
Length = 221
Score = 125 bits (314), Expect = 1e-28
Identities = 70/183 (38%), Positives = 107/183 (58%), Gaps = 17/183 (9%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVD----------GERTVL 592
K + GD+ VGK+S L + +F T+G+DF+ K ++ G+R L
Sbjct: 11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70
Query: 593 QLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH-ETVPIML 651
QLWDTAGQERFRS+ ++FR A G LLL+D+T E+SFLN+R W+ ++ A+ E I+L
Sbjct: 71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVL 130
Query: 652 VGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
GNK+D+ D + ++ + LA YG + ETSA +G+NI +A+ L + KR
Sbjct: 131 CGNKSDLEDQRVVKEEEAI------ALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKR 184
Query: 712 TDK 714
++
Sbjct: 185 MER 187
>gi|34485706 Ras-related protein Rab-27A [Homo sapiens]
Length = 221
Score = 125 bits (314), Expect = 1e-28
Identities = 70/183 (38%), Positives = 107/183 (58%), Gaps = 17/183 (9%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVD----------GERTVL 592
K + GD+ VGK+S L + +F T+G+DF+ K ++ G+R L
Sbjct: 11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70
Query: 593 QLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH-ETVPIML 651
QLWDTAGQERFRS+ ++FR A G LLL+D+T E+SFLN+R W+ ++ A+ E I+L
Sbjct: 71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVL 130
Query: 652 VGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
GNK+D+ D + ++ + LA YG + ETSA +G+NI +A+ L + KR
Sbjct: 131 CGNKSDLEDQRVVKEEEAI------ALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKR 184
Query: 712 TDK 714
++
Sbjct: 185 MER 187
>gi|19923264 Ras-related protein Rab-27A [Homo sapiens]
Length = 221
Score = 125 bits (314), Expect = 1e-28
Identities = 70/183 (38%), Positives = 107/183 (58%), Gaps = 17/183 (9%)
Query: 543 KIVLAGDAAVGKSSFLMRLCKNEFRENISATLGVDFQMKTLIVD----------GERTVL 592
K + GD+ VGK+S L + +F T+G+DF+ K ++ G+R L
Sbjct: 11 KFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKRVVYRASGPDGATGRGQRIHL 70
Query: 593 QLWDTAGQERFRSIAKSYFRKADGVLLLYDVTCEKSFLNIREWVDMIEDAAH-ETVPIML 651
QLWDTAGQERFRS+ ++FR A G LLL+D+T E+SFLN+R W+ ++ A+ E I+L
Sbjct: 71 QLWDTAGQERFRSLTTAFFRDAMGFLLLFDLTNEQSFLNVRNWISQLQMHAYCENPDIVL 130
Query: 652 VGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKR 711
GNK+D+ D + ++ + LA YG + ETSA +G+NI +A+ L + KR
Sbjct: 131 CGNKSDLEDQRVVKEEEAI------ALAEKYGIPYFETSAANGTNISQAIEMLLDLIMKR 184
Query: 712 TDK 714
++
Sbjct: 185 MER 187
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,474,903
Number of Sequences: 37866
Number of extensions: 1210912
Number of successful extensions: 8122
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 286
Number of HSP's successfully gapped in prelim test: 872
Number of HSP's that attempted gapping in prelim test: 5687
Number of HSP's gapped (non-prelim): 2513
length of query: 740
length of database: 18,247,518
effective HSP length: 110
effective length of query: 630
effective length of database: 14,082,258
effective search space: 8871822540
effective search space used: 8871822540
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.